|
G |
Abl1 |
ABL proto-oncogene 1, non-receptor tyrosine kinase |
multiple interactions increases phosphorylation |
ISO |
EGF protein inhibits the reaction [Cytochalasin D results in increased phosphorylation of ABL1 protein] |
CTD |
PMID:21900236 |
|
NCBI chr 3:35,377,587...35,480,843
|
|
G |
Acta2 |
actin alpha 2, smooth muscle |
multiple interactions increases expression |
ISO EXP |
Cytochalasin D inhibits the reaction [Oxygen results in increased expression of ACTA2 mRNA]; Cytochalasin D inhibits the reaction [Oxygen results in increased expression of ACTA2 protein] Cytochalasin D results in increased expression of ACTA2 mRNA |
CTD |
PMID:11035001 PMID:23517783 |
|
NCBI chr 1:241,159,723...241,172,503
|
|
G |
Actg1 |
actin, gamma 1 |
multiple interactions |
ISO |
Cytochalasin D inhibits the reaction [UPF1 protein binds to ACTG1 protein]; Cytochalasin D inhibits the reaction [UPF2 protein binds to ACTG1 protein]; Cytochalasin D inhibits the reaction [UPF3B protein binds to ACTG1 protein] |
CTD |
PMID:28743738 |
|
NCBI chr10:106,118,106...106,120,951
|
|
G |
Cdh1 |
cadherin 1 |
multiple interactions increases expression |
ISO |
[Cytochalasin D results in increased expression of CDH1 protein] which results in decreased activity of RHOA protein; RHOA protein mutant form affects the reaction [Cytochalasin D results in increased expression of CDH1 protein] Cytochalasin D results in increased expression of CDH1 mRNA; Cytochalasin D results in increased expression of CDH1 protein |
CTD |
PMID:25756282 |
|
NCBI chr19:51,402,178...51,471,572
|
|
G |
Col1a1 |
collagen type I alpha 1 chain |
multiple interactions |
ISO |
Cytochalasin D inhibits the reaction [Oxygen results in increased expression of COL1A1 mRNA] |
CTD |
PMID:23517783 |
|
NCBI chr10:80,380,458...80,397,461
|
|
G |
Col1a2 |
collagen type I alpha 2 chain |
multiple interactions |
ISO |
Cytochalasin D inhibits the reaction [Oxygen results in increased expression of COL1A2 mRNA] |
CTD |
PMID:23517783 |
|
NCBI chr 4:33,518,557...33,553,484
|
|
G |
Csf2 |
colony stimulating factor 2 |
multiple interactions |
ISO |
Cytochalasin D inhibits the reaction [Particulate Matter results in increased secretion of CSF2 protein]; Cytochalasin D inhibits the reaction [Vehicle Emissions results in increased secretion of CSF2 protein] |
CTD |
PMID:10645887 |
|
NCBI chr10:38,887,692...38,889,673
|
|
G |
Cxcr1 |
C-X-C motif chemokine receptor 1 |
multiple interactions |
ISO |
Cytochalasin D promotes the reaction [CXCL8 protein results in decreased expression of CXCR1 protein] |
CTD |
PMID:11145710 |
|
NCBI chr 9:83,216,040...83,220,225
|
|
G |
Cxcr2 |
C-X-C motif chemokine receptor 2 |
multiple interactions |
ISO |
Cytochalasin D promotes the reaction [CXCL8 protein results in decreased expression of CXCR2 protein] |
CTD |
PMID:11145710 |
|
NCBI chr 9:75,729,493...75,735,868
|
|
G |
Egf |
epidermal growth factor |
multiple interactions |
ISO |
EGF protein inhibits the reaction [Cytochalasin D results in increased phosphorylation of ABL1 protein] |
CTD |
PMID:21900236 |
|
NCBI chr 2:220,893,660...220,976,331
|
|
G |
Egfr |
epidermal growth factor receptor |
multiple interactions |
ISO |
Cytochalasin D inhibits the reaction [Asbestos, Crocidolite results in decreased phosphorylation of EGFR protein] |
CTD |
PMID:15626777 |
|
NCBI chr14:95,378,626...95,551,358
|
|
G |
F3 |
coagulation factor III, tissue factor |
multiple interactions |
ISO |
Cytochalasin D inhibits the reaction [Particulate Matter results in increased expression of F3 mRNA] |
CTD |
PMID:25858758 |
|
NCBI chr 2:212,511,675...212,523,375
|
|
G |
Gpx1 |
glutathione peroxidase 1 |
affects localization |
ISO |
Cytochalasin D affects the localization of GPX1 mRNA mutant form |
CTD |
PMID:28743738 |
|
NCBI chr 8:117,905,462...117,906,588
|
|
G |
Icam1 |
intercellular adhesion molecule 1 |
multiple interactions |
ISO |
Cytochalasin D inhibits the reaction [TNF protein affects the localization of ICAM1 protein] |
CTD |
PMID:15034928 |
|
NCBI chr 8:27,829,688...27,841,618
|
|
G |
Ifng |
interferon gamma |
multiple interactions |
ISO |
Cytochalasin D promotes the reaction [[IFNG protein co-treated with IL1B protein co-treated with TNF protein] results in increased expression of NOS2 mRNA] |
CTD |
PMID:12799187 |
|
NCBI chr 7:55,789,180...55,793,216
|
|
G |
Ikbkb |
inhibitor of nuclear factor kappa B kinase subunit beta |
increases phosphorylation multiple interactions |
ISO |
Cytochalasin D results in increased phosphorylation of IKBKB protein Cytochalasin D results in decreased localization of [IKBKB protein binds to NFKBIA protein] |
CTD |
PMID:17029595 |
|
NCBI chr16:76,021,968...76,075,717
|
|
G |
Il1a |
interleukin 1 alpha |
multiple interactions |
ISO |
Cytochalasin D inhibits the reaction [Quartz results in increased import of IL1A protein]; Cytochalasin D promotes the reaction [Quartz results in increased secretion of IL1A protein] |
CTD |
PMID:36840754 |
|
NCBI chr 3:136,979,804...136,990,236
|
|
G |
Il1b |
interleukin 1 beta |
multiple interactions |
ISO |
Cytochalasin D inhibits the reaction [[Lipopolysaccharides co-treated with Silicon Dioxide] results in increased cleavage of and results in increased secretion of IL1B protein]; Cytochalasin D inhibits the reaction [[Lipopolysaccharides co-treated with Uric Acid] results in increased cleavage of and results in increased secretion of IL1B protein]; Cytochalasin D inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with aluminum sulfate] results in increased secretion of IL1B protein]; Cytochalasin D inhibits the reaction [Asbestos, Crocidolite results in increased secretion of IL1B protein]; Cytochalasin D inhibits the reaction [Nanotubes, Carbon results in increased secretion of IL1B protein]; Cytochalasin D inhibits the reaction [titanium dioxide results in increased secretion of IL1B protein]; Cytochalasin D inhibits the reaction [Uric Acid results in increased secretion of IL1B protein]; Cytochalasin D promotes the reaction [[IFNG protein co-treated with IL1B protein co-treated with TNF protein] results in increased expression of NOS2 mRNA] Cytochalasin D inhibits the reaction [[Air Pollutants results in increased abundance of Particulate Matter] which results in increased expression of IL1B mRNA]; Cytochalasin D inhibits the reaction [[Lipopolysaccharides co-treated with Silicon Dioxide] results in increased cleavage of and results in increased secretion of IL1B protein]; Cytochalasin D inhibits the reaction [[Lipopolysaccharides co-treated with Uric Acid] results in increased cleavage of and results in increased secretion of IL1B protein] |
CTD |
PMID:12799187 PMID:18403674 PMID:18604214 PMID:24158569 PMID:24760326 PMID:30320338 PMID:37062408 More...
|
|
NCBI chr 3:137,030,200...137,036,581
|
|
G |
Il6 |
interleukin 6 |
decreases chemical synthesis increases stability |
ISO |
Cytochalasin D results in decreased chemical synthesis of IL6 protein Cytochalasin D results in increased stability of IL6 mRNA |
CTD |
PMID:16499908 |
|
NCBI chr 4:5,889,999...5,894,575
|
|
G |
Ivns1abp |
influenza virus NS1A binding protein |
increases response to substance |
ISO |
IVNS1ABP gene mutant form results in increased susceptibility to Cytochalasin D |
CTD |
PMID:15485691 |
|
NCBI chr13:65,977,069...65,996,685
|
|
G |
Ldha |
lactate dehydrogenase A |
multiple interactions |
ISO |
Cytochalasin D inhibits the reaction [Quartz results in increased activity of and results in increased secretion of LDHA protein] |
CTD |
PMID:36840754 |
|
NCBI chr 1:97,371,823...97,381,247
|
|
G |
Mmp9 |
matrix metallopeptidase 9 |
multiple interactions |
ISO |
Cytochalasin D promotes the reaction [TNF results in increased expression of MMP9 mRNA] |
CTD |
PMID:17560598 |
|
NCBI chr 3:174,103,474...174,111,434
|
|
G |
Mrtfa |
myocardin related transcription factor A |
multiple interactions |
ISO |
Cytochalasin D inhibits the reaction [Oxygen affects the localization of MRTFA protein] |
CTD |
PMID:23517783 |
|
NCBI chr 7:112,544,305...112,714,418
|
|
G |
Nfatc4 |
nuclear factor of activated T-cells 4 |
decreases localization |
ISO |
Cytochalasin D results in decreased localization of NFATC4 protein |
CTD |
PMID:17044076 |
|
NCBI chr15:33,256,912...33,284,522
|
|
G |
Nfkbia |
NFKB inhibitor alpha |
increases phosphorylation multiple interactions |
ISO |
Cytochalasin D results in increased phosphorylation of NFKBIA protein Cytochalasin D results in decreased localization of [IKBKB protein binds to NFKBIA protein] |
CTD |
PMID:17029595 |
|
NCBI chr 6:78,593,844...78,597,307
|
|
G |
Nlrp3 |
NLR family, pyrin domain containing 3 |
decreases expression multiple interactions |
ISO |
Cytochalasin D results in decreased expression of NLRP3 mRNA Cytochalasin D inhibits the reaction [[Air Pollutants results in increased abundance of Particulate Matter] which results in increased expression of NLRP3 mRNA] |
CTD |
PMID:37062408 |
|
NCBI chr10:44,826,299...44,853,373
|
|
G |
Nos2 |
nitric oxide synthase 2 |
multiple interactions |
ISO |
Cytochalasin D promotes the reaction [[IFNG protein co-treated with IL1B protein co-treated with TNF protein] results in increased expression of NOS2 mRNA] |
CTD |
PMID:12799187 |
|
NCBI chr10:64,313,335...64,349,221
|
|
G |
P2rx1 |
purinergic receptor P2X 1 |
decreases activity |
ISO |
Cytochalasin D results in decreased activity of P2RX1 protein |
CTD |
PMID:21757694 |
|
NCBI chr10:57,618,586...57,633,648
|
|
G |
Pdx1 |
pancreatic and duodenal homeobox 1 |
decreases uptake |
ISO |
Cytochalasin D results in decreased uptake of PDX1 protein |
CTD |
PMID:16405074 |
|
NCBI chr12:12,793,957...12,799,156
|
|
G |
Plat |
plasminogen activator, tissue type |
increases expression |
ISO |
Cytochalasin D results in increased expression of PLAT |
CTD |
PMID:12371961 |
|
NCBI chr16:75,943,061...76,022,037
|
|
G |
Rhoa |
ras homolog family member A |
multiple interactions |
ISO |
[Cytochalasin D results in increased expression of CDH1 protein] which results in decreased activity of RHOA protein; RHOA protein mutant form affects the reaction [Cytochalasin D results in increased expression of CDH1 protein] |
CTD |
PMID:25756282 |
|
NCBI chr 8:117,870,548...117,904,303
|
|
G |
Rs1 |
retinoschisin 1 |
decreases secretion |
ISO |
Cytochalasin D results in decreased secretion of RS1 protein |
CTD |
PMID:21738583 |
|
NCBI chr X:37,771,135...37,800,894
|
|
G |
Slc31a1 |
solute carrier family 31 member 1 |
multiple interactions |
ISO |
Cytochalasin D inhibits the reaction [Cisplatin results in increased degradation of SLC31A1 protein] |
CTD |
PMID:17108132 |
|
NCBI chr 5:75,814,744...75,844,241
|
|
G |
Smad1 |
SMAD family member 1 |
affects localization |
ISO |
Cytochalasin D affects the localization of SMAD1 protein |
CTD |
PMID:25756282 |
|
NCBI chr19:45,417,430...45,477,962
|
|
G |
Smad2 |
SMAD family member 2 |
affects localization |
ISO |
Cytochalasin D affects the localization of SMAD2 protein |
CTD |
PMID:25756282 |
|
NCBI chr18:72,124,792...72,193,345
|
|
G |
Smad3 |
SMAD family member 3 |
affects localization |
ISO |
Cytochalasin D affects the localization of SMAD3 protein |
CTD |
PMID:25756282 |
|
NCBI chr 8:64,126,829...64,236,960
|
|
G |
Snai1 |
snail family transcriptional repressor 1 |
affects localization |
ISO |
Cytochalasin D affects the localization of SNAI1 protein |
CTD |
PMID:25756282 |
|
NCBI chr 3:176,667,476...176,671,965
|
|
G |
Stat1 |
signal transducer and activator of transcription 1 |
multiple interactions |
ISO |
Cytochalasin D deficiency results in decreased activity of and affects the localization of STAT1 protein |
CTD |
PMID:28086195 |
|
NCBI chr 9:56,911,522...56,951,926
|
|
G |
Stat3 |
signal transducer and activator of transcription 3 |
multiple interactions |
ISO |
Cytochalasin D deficiency results in decreased activity of and affects the localization of STAT3 protein |
CTD |
PMID:28086195 |
|
NCBI chr10:86,311,528...86,363,513
|
|
G |
Tagln |
transgelin |
increases expression |
EXP |
Cytochalasin D results in increased expression of TAGLN mRNA |
CTD |
PMID:11035001 |
|
NCBI chr 8:55,121,647...55,127,121
|
|
G |
Tnf |
tumor necrosis factor |
multiple interactions |
ISO |
Cytochalasin D inhibits the reaction [TNF protein affects the localization of ICAM1 protein]; Cytochalasin D inhibits the reaction [TNF protein affects the localization of VCAM1 protein]; Cytochalasin D inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]; Cytochalasin D promotes the reaction [[IFNG protein co-treated with IL1B protein co-treated with TNF protein] results in increased expression of NOS2 mRNA]; Cytochalasin D promotes the reaction [TNF results in increased expression of MMP9 mRNA] Cytochalasin D inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; Cytochalasin D inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein] |
CTD |
PMID:8409756 PMID:12799187 PMID:15034928 PMID:17560598 |
|
NCBI chr20:3,626,685...3,629,303
|
|
G |
Txn1 |
thioredoxin 1 |
multiple interactions |
ISO |
Cytochalasin D inhibits the reaction [Cadmium Chloride affects the localization of TXN protein] |
CTD |
PMID:22961094 |
|
NCBI chr 5:77,507,455...77,519,685
|
|
G |
Upf1 |
UPF1, RNA helicase and ATPase |
affects localization multiple interactions |
ISO |
Cytochalasin D affects the localization of UPF1 protein Cytochalasin D inhibits the reaction [UPF1 protein binds to ACTG1 protein] |
CTD |
PMID:28743738 |
|
NCBI chr16:19,076,594...19,097,365
|
|
G |
Upf2 |
UPF2, regulator of nonsense mediated mRNA decay |
multiple interactions |
ISO |
Cytochalasin D inhibits the reaction [UPF2 protein binds to ACTG1 protein] |
CTD |
PMID:28743738 |
|
NCBI chr17:72,224,575...72,335,896
|
|
G |
Upf3b |
UPF3B, regulator of nonsense mediated mRNA decay |
multiple interactions |
ISO |
Cytochalasin D inhibits the reaction [UPF3B protein binds to ACTG1 protein] |
CTD |
PMID:28743738 |
|
NCBI chr X:116,335,308...116,353,332
|
|
G |
Vcam1 |
vascular cell adhesion molecule 1 |
multiple interactions |
ISO |
Cytochalasin D inhibits the reaction [TNF protein affects the localization of VCAM1 protein]; Cytochalasin D inhibits the reaction [TNF protein results in increased expression of VCAM1 protein] |
CTD |
PMID:15034928 |
|
NCBI chr 2:206,723,050...206,742,783
|
|