CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: Genipin
Accession: CHEBI:5298
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Definition: An iridoid monoterpenoid that has formula C11H14O5.
Synonyms: related_synonym: Formula=C11H14O5; InChI=1S/C11H14O5/c1-15-10(13)8-5-16-11(14)9-6(4-12)2-3-7(8)9/h2,5,7,9,11-12,14H,3-4H2,1H3/t7-,9-,11-/m1/s1; InChIKey=AZKVWQKMDGGDSV-BCMRRPTOSA-N; SMILES=COC(=O)C1=CO[C@@H](O)[C@H]2[C@@H]1CC=C2CO
xref: AGR:IND606358367; AGR:IND606366595; CAS:6902-77-8; KEGG:C09780; KNApSAcK:C00000321
xref_mesh: MESH:C007834
xref: PMID:31351462; PMID:31466050; PMID:31571857; PMID:31605673; PMID:31614580; PMID:31615330; PMID:31646411; PMID:31665713; PMID:31671698; PMID:31682429; PMID:31706565; PMID:31720526; PMID:31724991; PPR:PPR99870
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Akt1
AKT serine/threonine kinase 1
multiple interactions
ISO
genipin inhibits the reaction [Oxygen deficiency results in increased phosphorylation of AKT1 protein]
CTD
PMID:29630948
NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
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Angptl4
angiopoietin-like 4
multiple interactions
ISO
genipin inhibits the reaction [Lipopolysaccharides results in increased expression of ANGPTL4 mRNA]
CTD
PMID:22687549
NCBI chr 7:18,627,814...18,634,043
Ensembl chr 7:18,627,808...18,634,079
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Bax
BCL2 associated X, apoptosis regulator
increases expression
ISO
genipin results in increased expression of BAX mRNA
CTD
PMID:22245672
NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
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Bcas2
BCAS2, pre-mRNA processing factor
multiple interactions
ISO
genipin inhibits the reaction [Lipopolysaccharides results in increased expression of BCAS2 mRNA]
CTD
PMID:22687549
NCBI chr 2:205,662,633...205,670,514
Ensembl chr 2:205,662,588...205,670,511
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Bcl2
BCL2, apoptosis regulator
decreases expression
ISO
genipin results in decreased expression of BCL2 mRNA
CTD
PMID:22245672
NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
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Birc3
baculoviral IAP repeat-containing 3
multiple interactions
ISO
genipin inhibits the reaction [Lipopolysaccharides results in increased expression of BIRC3 mRNA]
CTD
PMID:22687549
NCBI chr 8:6,048,590...6,076,828
Ensembl chr 8:6,048,969...6,076,598
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Bst2
bone marrow stromal cell antigen 2
multiple interactions
ISO
genipin inhibits the reaction [Lipopolysaccharides results in increased expression of BST2 mRNA]
CTD
PMID:22687549
NCBI chr16:19,938,781...19,942,353
Ensembl chr16:19,938,784...19,942,353
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Ca9
carbonic anhydrase 9
multiple interactions
ISO
genipin inhibits the reaction [Oxygen deficiency results in increased expression of CA9 mRNA]
CTD
PMID:29630948
NCBI chr 5:59,008,277...59,015,535
Ensembl chr 5:59,008,933...59,015,528
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Calhm6
calcium homeostasis modulator family member 6
multiple interactions
ISO
genipin inhibits the reaction [Lipopolysaccharides results in increased expression of CALHM6 mRNA]
CTD
PMID:22687549
NCBI chr20:27,681,138...27,683,580
Ensembl chr20:27,681,036...27,682,861
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Casp3
caspase 3
increases activity
ISO
genipin results in increased activity of CASP3 protein
CTD
PMID:22245672
NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
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Ccr7
C-C motif chemokine receptor 7
multiple interactions
ISO
genipin inhibits the reaction [Lipopolysaccharides results in increased expression of CCR7 mRNA]
CTD
PMID:22687549
NCBI chr10:87,057,335...87,067,444
Ensembl chr10:87,057,136...87,067,456
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Ccrl2
C-C motif chemokine receptor like 2
multiple interactions
ISO
genipin inhibits the reaction [Lipopolysaccharides results in increased expression of CCRL2 mRNA]
CTD
PMID:22687549
NCBI chr 8:119,324,298...119,326,954
Ensembl chr 8:119,324,613...119,326,938
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Cd14
CD14 molecule
multiple interactions
ISO
genipin inhibits the reaction [Lipopolysaccharides results in increased expression of CD14 mRNA]
CTD
PMID:22687549
NCBI chr18:29,560,341...29,562,290
Ensembl chr18:29,560,365...29,562,153
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Cd40
CD40 molecule
multiple interactions
ISO
genipin inhibits the reaction [Lipopolysaccharides results in increased expression of CD40 mRNA]
CTD
PMID:22687549
NCBI chr 3:161,519,789...161,534,943
Ensembl chr 3:161,519,743...161,534,704
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Cebpd
CCAAT/enhancer binding protein delta
multiple interactions
ISO
genipin inhibits the reaction [Lipopolysaccharides results in increased expression of CEBPD mRNA]
CTD
PMID:22687549
NCBI chr11:89,008,008...89,009,146
Ensembl chr11:89,008,008...89,009,146
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Csf3
colony stimulating factor 3
multiple interactions
ISO
genipin inhibits the reaction [Lipopolysaccharides results in increased expression of CSF3 mRNA]
CTD
PMID:22687549
NCBI chr10:86,616,785...86,619,160
Ensembl chr10:86,616,785...86,619,157
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Cxcl10
C-X-C motif chemokine ligand 10
multiple interactions
ISO
genipin inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL10 mRNA]
CTD
PMID:22687549
NCBI chr14:17,210,733...17,212,930
Ensembl chr14:17,210,733...17,212,930
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Cxcl6
C-X-C motif chemokine ligand 6
multiple interactions
ISO
genipin inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL5 mRNA]
CTD
PMID:22687549
NCBI chr14:18,860,201...18,920,839
Ensembl chr14:18,860,264...18,862,407
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Cxcl9
C-X-C motif chemokine ligand 9
multiple interactions
ISO
genipin inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL9 mRNA]
CTD
PMID:22687549
NCBI chr14:17,228,832...17,233,743
Ensembl chr14:17,228,856...17,234,712
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Dnm1l
dynamin 1-like
multiple interactions
ISO
genipin inhibits the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of DNM1L protein]
CTD
PMID:28477916
NCBI chr11:88,830,968...88,882,271
Ensembl chr11:88,830,957...88,880,198
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Hif1a
hypoxia inducible factor 1 subunit alpha
multiple interactions
ISO
genipin affects the reaction [[Oxygen deficiency co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] affects the expression of HIF1A protein]; genipin affects the reaction [[Oxygen deficiency co-treated with Cycloheximide] affects the expression of HIF1A protein]; genipin inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]
CTD
PMID:29630948
NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
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Hmox1
heme oxygenase 1
increases expression
ISO
genipin results in increased expression of HMOX1 protein
CTD
PMID:24413982
NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
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Ifi35
interferon-induced protein 35
multiple interactions
ISO
genipin inhibits the reaction [Lipopolysaccharides results in increased expression of IFI35 mRNA]
CTD
PMID:22687549
NCBI chr10:89,358,376...89,366,628
Ensembl chr10:89,358,376...89,366,626
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Ifi44
interferon-induced protein 44
multiple interactions
ISO
genipin inhibits the reaction [Lipopolysaccharides results in increased expression of IFI44 mRNA]
CTD
PMID:22687549
NCBI chr 2:256,897,765...256,915,591
Ensembl chr 2:256,897,772...256,915,569
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Ifih1
interferon induced with helicase C domain 1
multiple interactions
ISO
genipin inhibits the reaction [Lipopolysaccharides results in increased expression of IFIH1 mRNA]
CTD
PMID:22687549
NCBI chr 3:48,557,696...48,604,097
Ensembl chr 3:48,557,696...48,604,097
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Ifit3
interferon-induced protein with tetratricopeptide repeats 3
multiple interactions
ISO
genipin inhibits the reaction [Lipopolysaccharides results in increased expression of IFIT3 mRNA]
CTD
PMID:22687549
NCBI chr 1:252,906,234...252,911,377
Ensembl chr 1:252,906,234...252,911,382
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Il1b
interleukin 1 beta
multiple interactions
ISO
genipin inhibits the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of IL1B protein]; genipin inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein]
CTD
PMID:22687549 PMID:28477916
NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
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Il1rn
interleukin 1 receptor antagonist
multiple interactions
ISO
genipin inhibits the reaction [Lipopolysaccharides results in increased expression of IL1RN mRNA]
CTD
PMID:22687549
NCBI chr 3:1,449,778...1,468,624
Ensembl chr 3:1,452,644...1,468,614
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Il6
interleukin 6
multiple interactions
ISO
genipin inhibits the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of IL6 protein]
CTD
PMID:28477916
NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
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Isg15
ISG15 ubiquitin-like modifier
multiple interactions
ISO
genipin inhibits the reaction [Lipopolysaccharides results in increased expression of ISG15 mRNA]
CTD
PMID:22687549
NCBI chr 5:173,624,862...173,629,124
Ensembl chr 5:173,624,310...173,626,248
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Klf2
Kruppel-like factor 2
multiple interactions
ISO
genipin inhibits the reaction [Lipopolysaccharides results in increased expression of KLF2 mRNA]
CTD
PMID:22687549
NCBI chr16:19,223,087...19,225,037
Ensembl chr16:19,223,087...19,225,037
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Laptm5
lysosomal protein transmembrane 5
multiple interactions
ISO
genipin inhibits the reaction [Lipopolysaccharides results in decreased expression of LAPTM5 mRNA]
CTD
PMID:22687549
NCBI chr 5:149,015,793...149,069,719
Ensembl chr 5:149,047,681...149,069,719
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Map3k8
mitogen-activated protein kinase kinase kinase 8
multiple interactions
ISO
genipin inhibits the reaction [Lipopolysaccharides results in increased expression of MAP3K8 mRNA]
CTD
PMID:22687549
NCBI chr17:56,109,403...56,129,925
Ensembl chr17:56,109,549...56,129,919
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Mapk1
mitogen activated protein kinase 1
multiple interactions decreases phosphorylation
ISO
genipin inhibits the reaction [Oxygen deficiency results in increased phosphorylation of MAPK1 protein] genipin results in decreased phosphorylation of MAPK1 protein
CTD
PMID:29630948
NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
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Mapk3
mitogen activated protein kinase 3
decreases phosphorylation multiple interactions
ISO
genipin results in decreased phosphorylation of MAPK3 protein genipin inhibits the reaction [Oxygen deficiency results in increased phosphorylation of MAPK3 protein]
CTD
PMID:29630948
NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
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Megf11
multiple EGF-like-domains 11
multiple interactions
ISO
genipin inhibits the reaction [Lipopolysaccharides results in increased expression of MEGF11 mRNA]
CTD
PMID:22687549
NCBI chr 8:69,859,256...70,191,070
Ensembl chr 8:69,971,778...70,184,742
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Mfn2
mitofusin 2
multiple interactions
ISO
genipin inhibits the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in decreased expression of MFN2 protein]
CTD
PMID:28477916
NCBI chr 5:164,684,244...164,715,414
Ensembl chr 5:164,684,509...164,714,145
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Mmp13
matrix metallopeptidase 13
multiple interactions
ISO
genipin inhibits the reaction [Lipopolysaccharides results in increased expression of MMP13 mRNA]
CTD
PMID:22687549
NCBI chr 8:5,522,739...5,533,018
Ensembl chr 8:5,522,739...5,533,018
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Mmp2
matrix metallopeptidase 2
multiple interactions
ISO
genipin inhibits the reaction [Oxygen deficiency results in increased expression of MMP2 protein]
CTD
PMID:29630948
NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
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Mmp9
matrix metallopeptidase 9
multiple interactions
ISO
genipin inhibits the reaction [Oxygen deficiency results in increased expression of MMP9 protein]
CTD
PMID:29630948
NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
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Mx2
MX dynamin like GTPase 2
multiple interactions
ISO
genipin inhibits the reaction [Lipopolysaccharides results in increased expression of MX1 mRNA]
CTD
PMID:22687549
NCBI chr11:38,035,306...38,066,185
Ensembl chr11:38,035,450...38,059,950
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Myd88
MYD88, innate immune signal transduction adaptor
multiple interactions
ISO
genipin inhibits the reaction [Lipopolysaccharides results in increased expression of MYD88 mRNA]
CTD
PMID:22687549
NCBI chr 8:128,022,512...128,027,462
Ensembl chr 8:128,022,473...128,026,841
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Nfe2l2
nuclear factor, erythroid 2-like 2
multiple interactions
ISO
[Lipopolysaccharides co-treated with genipin] results in increased activity of NFE2L2 protein
CTD
PMID:30114225 PMID:30203046
NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
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Nqo1
NAD(P)H quinone dehydrogenase 1
increases expression
ISO
genipin results in increased expression of NQO1 protein
CTD
PMID:24413982
NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
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Nrarp
Notch-regulated ankyrin repeat protein
multiple interactions
ISO
genipin inhibits the reaction [Lipopolysaccharides results in decreased expression of NRARP mRNA]
CTD
PMID:22687549
NCBI chr 3:2,396,143...2,398,697
Ensembl chr 3:2,396,143...2,398,689
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Nrf1
nuclear respiratory factor 1
multiple interactions
ISO
genipin inhibits the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in decreased expression of NRF1 protein]
CTD
PMID:28477916
NCBI chr 4:57,335,732...57,445,317
Ensembl chr 4:57,378,069...57,445,341
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Oas2
2'-5' oligoadenylate synthetase 2
multiple interactions
ISO
genipin inhibits the reaction [Lipopolysaccharides results in increased expression of OAS2 mRNA]
CTD
PMID:22687549
NCBI chr12:41,341,417...41,363,124
Ensembl chr12:41,340,815...41,363,161
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Oasl
2'-5'-oligoadenylate synthetase-like
multiple interactions
ISO
genipin inhibits the reaction [Lipopolysaccharides results in increased expression of OASL mRNA]
CTD
PMID:22687549
NCBI chr12:47,444,138...47,456,680
Ensembl chr12:47,444,104...47,456,894
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Osmr
oncostatin M receptor
multiple interactions
ISO
genipin inhibits the reaction [Lipopolysaccharides results in increased expression of OSMR mRNA]
CTD
PMID:22687549
NCBI chr 2:56,107,491...56,163,522
Ensembl chr 2:56,110,777...56,151,531
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Pde4b
phosphodiesterase 4B
multiple interactions
ISO
genipin inhibits the reaction [Lipopolysaccharides results in increased expression of PDE4B mRNA]
CTD
PMID:22687549
NCBI chr 5:121,759,236...122,136,814
Ensembl chr 5:121,952,977...122,136,814
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Phf11
PHD finger protein 11
multiple interactions
ISO
genipin inhibits the reaction [Lipopolysaccharides results in increased expression of PHF11D mRNA]
CTD
PMID:22687549
NCBI chr15:38,692,817...39,683,417
Ensembl chr15:38,647,779...38,709,984
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Pink1
PTEN induced kinase 1
multiple interactions
ISO
genipin inhibits the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of PINK1 protein]
CTD
PMID:28477916
NCBI chr 5:156,677,146...156,689,258
Ensembl chr 5:156,677,146...156,689,415
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Plau
plasminogen activator, urokinase
multiple interactions
ISO
genipin inhibits the reaction [Oxygen deficiency results in increased expression of PLAU protein]
CTD
PMID:29630948
NCBI chr15:3,644,296...3,650,765
Ensembl chr15:3,644,769...3,650,819
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Ppargc1a
PPARG coactivator 1 alpha
multiple interactions
ISO
genipin inhibits the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in decreased expression of PPARGC1A protein]; sirtinol inhibits the reaction [genipin inhibits the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in decreased expression of PPARGC1A protein]]
CTD
PMID:28477916
NCBI chr14:63,095,291...63,190,688
Ensembl chr14:63,095,720...63,187,009
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Prkn
parkin RBR E3 ubiquitin protein ligase
multiple interactions
ISO
genipin inhibits the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in decreased expression of PRKN protein]; sirtinol inhibits the reaction [genipin inhibits the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in decreased expression of PRKN protein]]
CTD
PMID:28477916
NCBI chr 1:48,880,015...50,069,998
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Psmb8
proteasome 20S subunit beta 8
multiple interactions
ISO
genipin inhibits the reaction [Lipopolysaccharides results in increased expression of PSMB8 mRNA]
CTD
PMID:22687549
NCBI chr20:3,990,809...3,993,772
Ensembl chr20:3,990,613...3,993,769
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Rnase3
ribonuclease A family member 3
multiple interactions
ISO
genipin inhibits the reaction [Lipopolysaccharides results in increased expression of EAR1 mRNA]
CTD
PMID:22687549
NCBI chr15:28,216,744...28,217,614
Ensembl chr15:28,216,744...28,217,614
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Rsad2
radical S-adenosyl methionine domain containing 2
multiple interactions
ISO
genipin inhibits the reaction [Lipopolysaccharides results in increased expression of RSAD2 mRNA]
CTD
PMID:22687549
NCBI chr 6:45,655,947...45,669,083
Ensembl chr 6:45,655,954...45,669,148
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Samhd1
SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1
multiple interactions
ISO
genipin inhibits the reaction [Lipopolysaccharides results in increased expression of SAMHD1 mRNA]
CTD
PMID:22687549
NCBI chr 3:153,210,829...153,250,705
Ensembl chr 3:153,210,829...153,250,641
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Sbk1
SH3 domain binding kinase 1
multiple interactions
ISO
genipin inhibits the reaction [Lipopolysaccharides results in decreased expression of SBK1 mRNA]
CTD
PMID:22687549
NCBI chr 1:197,636,230...197,681,031
Ensembl chr 1:67,368,384...67,390,141 Ensembl chr 1:67,368,384...67,390,141
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Sirt1
sirtuin 1
multiple interactions
ISO
genipin inhibits the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in decreased expression of SIRT1 protein]; sirtinol inhibits the reaction [genipin inhibits the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in decreased expression of SIRT1 protein]]
CTD
PMID:28477916
NCBI chr20:26,831,971...26,851,587
Ensembl chr20:26,833,357...26,852,199
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Slc10a6
solute carrier family 10 member 6
multiple interactions
ISO
genipin inhibits the reaction [Lipopolysaccharides results in increased expression of SLC10A6 mRNA]
CTD
PMID:22687549
NCBI chr14:7,618,022...7,682,377
Ensembl chr14:7,618,022...7,682,377
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Slc16a11
solute carrier family 16, member 11
multiple interactions
ISO
genipin inhibits the reaction [Lipopolysaccharides results in increased expression of SLC16A11 mRNA]
CTD
PMID:22687549
NCBI chr10:56,822,697...56,826,480
Ensembl chr10:56,822,756...56,826,479
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Slc2a1
solute carrier family 2 member 1
multiple interactions
ISO
genipin inhibits the reaction [Oxygen deficiency results in increased expression of SLC2A1 mRNA]
CTD
PMID:29630948
NCBI chr 5:138,154,677...138,182,897
Ensembl chr 5:138,154,673...138,182,897
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Snrk
SNF related kinase
multiple interactions
ISO
genipin inhibits the reaction [Lipopolysaccharides results in decreased expression of SNRK mRNA]
CTD
PMID:22687549
NCBI chr 8:130,749,806...130,805,225
Ensembl chr 8:130,749,838...130,803,597
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Sqstm1
sequestosome 1
multiple interactions
ISO
genipin inhibits the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of SQSTM1 protein]
CTD
PMID:28477916
NCBI chr10:35,704,728...35,716,316
Ensembl chr10:35,704,730...35,716,294
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Tap2
transporter 2, ATP binding cassette subfamily B member
multiple interactions
ISO
genipin inhibits the reaction [Lipopolysaccharides results in increased expression of TAP2 mRNA]
CTD
PMID:22687549
NCBI chr20:3,995,544...4,009,587
Ensembl chr20:3,995,544...4,009,587
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Tek
TEK receptor tyrosine kinase
multiple interactions
ISO
genipin inhibits the reaction [Lipopolysaccharides results in decreased expression of TEK mRNA]
CTD
PMID:22687549
NCBI chr 5:113,725,717...113,852,799
Ensembl chr 5:113,725,717...113,852,799
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Tfam
transcription factor A, mitochondrial
multiple interactions
ISO
genipin inhibits the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in decreased expression of TFAM protein]
CTD
PMID:28477916
NCBI chr20:18,594,057...18,606,106
Ensembl chr20:18,594,037...18,606,151
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Tnf
tumor necrosis factor
multiple interactions
ISO
genipin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]
CTD
PMID:22687549
NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
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Tor3a
torsin family 3, member A
multiple interactions
ISO
genipin inhibits the reaction [Lipopolysaccharides results in increased expression of TOR3A mRNA]
CTD
PMID:22687549
NCBI chr13:74,246,504...74,277,694
Ensembl chr13:74,252,405...74,276,964
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Trex1
three prime repair exonuclease 1
multiple interactions
ISO
genipin inhibits the reaction [Lipopolysaccharides results in increased expression of TREX1 mRNA]
CTD
PMID:22687549
NCBI chr 8:117,796,127...117,797,427
Ensembl chr 8:117,796,128...117,797,427
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Ubd
ubiquitin D
multiple interactions
ISO
genipin inhibits the reaction [Lipopolysaccharides results in increased expression of UBD mRNA]
CTD
PMID:22687549
NCBI chr20:1,876,175...1,878,126
Ensembl chr20:1,876,173...1,897,814
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Usp18
ubiquitin specific peptidase 18
multiple interactions
ISO
genipin inhibits the reaction [Lipopolysaccharides results in increased expression of USP18 mRNA]
CTD
PMID:22687549
NCBI chr 4:153,812,312...153,834,374
Ensembl chr 4:153,805,993...153,834,430
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Vegfa
vascular endothelial growth factor A
multiple interactions decreases expression
ISO
genipin inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA mRNA]; genipin inhibits the reaction [Oxygen deficiency results in increased secretion of VEGFA protein] genipin results in decreased expression of VEGFA mRNA
CTD
PMID:29630948
NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
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