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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:rhodamine 123(1+)
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Accession:CHEBI:52894 term browser browse the term
Definition:A cationic fluorescent dye derived from 9-phenylxanthene.
Synonyms:exact_synonym: 6-amino-9-[2-(methoxycarbonyl)phenyl]-3H-xanthen-3-iminium
 related_synonym: Formula=C21H17N2O3;   InChI=1S/C21H16N2O3/c1-25-21(24)15-5-3-2-4-14(15)20-16-8-6-12(22)10-18(16)26-19-11-13(23)7-9-17(19)20/h2-11,22H,23H2,1H3/p+1;   InChIKey=FCGVBHISQBBIQF-UHFFFAOYSA-O;   SMILES=COC(=O)c1ccccc1-c1c2ccc(N)cc2oc2cc(=[NH2+])ccc12;   rhodamine 123 cation



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rhodamine 123 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions
increases export
ISO
EXP
5-oxo-hexahydroquinoline analog inhibits the reaction [ABCB1 protein results in increased export of Rhodamine 123]; abemaciclib inhibits the reaction [ABCB1 protein results in increased export of Rhodamine 123]; betulin inhibits the reaction [ABCB1 protein results in increased export of Rhodamine 123]; CEP 33779 inhibits the reaction [ABCB1 protein results in increased export of Rhodamine 123]; Verapamil inhibits the reaction [ABCB1 protein results in increased export of Rhodamine 123]
[P-glycoprotein inducer and activator TX5 results in increased activity of ABCB1 protein] which results in increased export of Rhodamine 123; [Verapamil results in decreased activity of ABCB1 protein] inhibits the reaction [P-glycoprotein inducer and activator TX5 results in increased export of Rhodamine 123]
CTD PMID:25058526 PMID:27816545 PMID:30391378 PMID:31756430 PMID:33321149 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
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G Abcg2 ATP binding cassette subfamily G member 2 multiple interactions
increases export
ISO abemaciclib inhibits the reaction [ABCG2 protein results in increased export of Rhodamine 123] CTD PMID:27816545 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19800
    role 19751
      application 19498
        dye 1363
          xanthene dye 80
            rhodamine 123(1+) 2
              rhodamine 123 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19800
    subatomic particle 19799
      composite particle 19799
        hadron 19799
          baryon 19799
            nucleon 19799
              atomic nucleus 19799
                atom 19799
                  main group element atom 19698
                    p-block element atom 19698
                      carbon group element atom 19619
                        carbon atom 19609
                          organic molecular entity 19609
                            organic molecule 19549
                              organic cyclic compound 19343
                                organic heterocyclic compound 18584
                                  oxacycle 17609
                                    dibenzopyran 242
                                      xanthenes 236
                                        xanthene dye 80
                                          rhodamine 123(1+) 2
                                            rhodamine 123 2
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