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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:quinolinium ion
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Accession:CHEBI:52837 term browser browse the term
Synonyms:related_synonym: quinolinium ions



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dequalinium term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase decreases activity ISO Dequalinium results in decreased activity of ACHE protein CTD PMID:33400519 NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases expression ISO Dequalinium results in decreased expression of CCL2 protein CTD PMID:20116850 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 decreases expression ISO Dequalinium results in decreased expression of CCL3 protein CTD PMID:20116850 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
JBrowse link
G Ccl4 C-C motif chemokine ligand 4 decreases expression ISO Dequalinium results in decreased expression of CCL4 protein CTD PMID:20116850 NCBI chr10:68,466,394...68,468,229
Ensembl chr10:68,452,052...68,468,231
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 decreases expression ISO Dequalinium results in decreased expression of CCL5 protein CTD PMID:20116850 NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377
JBrowse link
G Il6r interleukin 6 receptor decreases expression ISO Dequalinium results in decreased expression of IL6R protein modified form CTD PMID:20116850 NCBI chr 2:175,289,157...175,347,719
Ensembl chr 2:175,298,686...175,347,536
JBrowse link
G Kcnn1 potassium calcium-activated channel subfamily N member 1 decreases activity ISO Dequalinium results in decreased activity of KCNN1 protein CTD PMID:10696100 NCBI chr16:18,574,858...18,598,585
Ensembl chr16:18,585,992...18,597,482
JBrowse link
G Kcnn2 potassium calcium-activated channel subfamily N member 2 decreases activity EXP Dequalinium results in decreased activity of KCNN2 protein CTD PMID:10696100 NCBI chr18:37,817,966...38,258,347
Ensembl chr18:37,817,957...38,258,347
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Dequalinium inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268
JBrowse link
G Tp53 tumor protein p53 increases expression ISO Dequalinium results in increased expression of TP53 protein CTD PMID:21548882 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Vegfa vascular endothelial growth factor A decreases expression ISO Dequalinium results in decreased expression of VEGFA protein CTD PMID:20116850 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
pyrvinium term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta2 actin alpha 2, smooth muscle multiple interactions EXP pyrvinium inhibits the reaction [Glyburide promotes the reaction [Isoproterenol results in increased expression of ACTA2 protein]]; pyrvinium inhibits the reaction [Isoproterenol results in increased expression of ACTA2 protein] CTD PMID:35305975 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases phosphorylation ISO pyrvinium results in decreased phosphorylation of AKT1 protein CTD PMID:27542212 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Axin2 axin 2 decreases expression ISO pyrvinium results in decreased expression of AXIN2 mRNA CTD PMID:21170416 NCBI chr10:93,893,830...93,927,042
Ensembl chr10:93,899,245...93,926,231
JBrowse link
G Casp3 caspase 3 multiple interactions EXP pyrvinium inhibits the reaction [Glyburide promotes the reaction [Isoproterenol results in increased activity of CASP3 protein]]; pyrvinium inhibits the reaction [Isoproterenol results in increased activity of CASP3 protein] CTD PMID:35305975 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Cat catalase multiple interactions EXP pyrvinium inhibits the reaction [Glyburide promotes the reaction [Isoproterenol results in decreased activity of CAT protein]]; pyrvinium inhibits the reaction [Isoproterenol results in decreased activity of CAT protein] CTD PMID:35305975 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases expression ISO pyrvinium results in decreased expression of CCL2 protein CTD PMID:20116850 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccne2 cyclin E2 multiple interactions ISO pyrvinium inhibits the reaction [PIK3CA protein modified form results in increased expression of CCNE2 mRNA] CTD PMID:27542212 NCBI chr 5:24,285,078...24,298,258
Ensembl chr 5:24,284,922...24,297,632
JBrowse link
G Ccng2 cyclin G2 multiple interactions ISO pyrvinium inhibits the reaction [PIK3CA protein modified form results in decreased expression of CCNG2 mRNA] CTD PMID:27542212 NCBI chr14:14,804,321...14,812,819
Ensembl chr14:14,804,322...14,812,830
JBrowse link
G Csgalnact1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 multiple interactions ISO pyrvinium inhibits the reaction [PIK3CA protein modified form results in decreased expression of CSGALNACT1 mRNA] CTD PMID:27542212 NCBI chr16:20,995,210...21,330,586
Ensembl chr16:21,235,784...21,330,319
JBrowse link
G Csnk1a1 casein kinase 1, alpha 1 decreases activity ISO pyrvinium results in decreased activity of CSNK1A1 protein CTD PMID:21170416 NCBI chr18:55,017,049...55,050,184
Ensembl chr18:55,017,055...55,049,271
JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions EXP pyrvinium inhibits the reaction [[Glyburide co-treated with Isoproterenol] results in increased expression of CTNNB1 mRNA]; pyrvinium inhibits the reaction [Glyburide promotes the reaction [Isoproterenol results in increased expression of CTNNB1 protein]]; pyrvinium inhibits the reaction [Isoproterenol results in increased expression of CTNNB1 mRNA]; pyrvinium inhibits the reaction [Isoproterenol results in increased expression of CTNNB1 protein] CTD PMID:35305975 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 decreases expression ISO pyrvinium results in decreased expression of DKK1 mRNA CTD PMID:21170416 NCBI chr 1:228,381,521...228,385,202
Ensembl chr 1:228,381,521...228,385,202
JBrowse link
G Dscc1 DNA replication and sister chromatid cohesion 1 multiple interactions ISO pyrvinium inhibits the reaction [PIK3CA protein modified form results in increased expression of DSCC1 mRNA] CTD PMID:27542212 NCBI chr 7:86,482,588...86,498,212
Ensembl chr 7:86,482,588...86,498,212
JBrowse link
G Endod1 endonuclease domain containing 1 multiple interactions ISO pyrvinium inhibits the reaction [PIK3CA protein modified form results in increased expression of ENDOD1 mRNA] CTD PMID:27542212 NCBI chr 8:11,209,113...11,238,507
Ensembl chr 8:11,211,110...11,238,892
JBrowse link
G Fn1 fibronectin 1 multiple interactions EXP pyrvinium inhibits the reaction [Glyburide promotes the reaction [Isoproterenol results in increased expression of FN1 protein]]; pyrvinium inhibits the reaction [Isoproterenol results in increased expression of FN1 protein] CTD PMID:35305975 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
JBrowse link
G Gpr35 G protein-coupled receptor 35 multiple interactions ISO pyrvinium binds to and results in increased activity of GPR35 protein CTD PMID:20919992 NCBI chr 9:93,527,165...93,539,573
Ensembl chr 9:93,527,127...93,539,299
JBrowse link
G Hbp1 HMG-box transcription factor 1 multiple interactions ISO pyrvinium inhibits the reaction [PIK3CA protein modified form results in decreased expression of HBP1 mRNA] CTD PMID:27542212 NCBI chr 6:48,529,633...48,555,775
Ensembl chr 6:48,529,372...48,555,787
JBrowse link
G Hey1 hes-related family bHLH transcription factor with YRPW motif 1 multiple interactions ISO pyrvinium inhibits the reaction [PIK3CA protein modified form results in decreased expression of HEY1 mRNA] CTD PMID:27542212 NCBI chr 2:93,096,605...93,100,316
Ensembl chr 2:93,095,498...93,100,312
JBrowse link
G Il17a interleukin 17A multiple interactions EXP pyrvinium inhibits the reaction [Glyburide promotes the reaction [Isoproterenol results in increased expression of IL17A protein]]; pyrvinium inhibits the reaction [Isoproterenol results in increased expression of IL17A protein] CTD PMID:35305975 NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP pyrvinium inhibits the reaction [Glyburide promotes the reaction [Isoproterenol results in increased expression of IL1B protein]]; pyrvinium inhibits the reaction [Isoproterenol results in increased expression of IL1B protein] CTD PMID:35305975 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6r interleukin 6 receptor decreases expression ISO pyrvinium results in decreased expression of IL6R protein modified form CTD PMID:20116850 NCBI chr 2:175,289,157...175,347,719
Ensembl chr 2:175,298,686...175,347,536
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO pyrvinium results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008
JBrowse link
G Kmt2a lysine methyltransferase 2A multiple interactions ISO pyrvinium inhibits the reaction [KMT2A protein results in decreased susceptibility to molibresib] CTD PMID:26367796 NCBI chr 8:45,116,763...45,193,320
Ensembl chr 8:45,118,814...45,193,181
JBrowse link
G Mpo myeloperoxidase multiple interactions EXP pyrvinium inhibits the reaction [Isoproterenol results in increased activity of MPO protein] CTD PMID:35305975 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases expression ISO pyrvinium results in decreased expression of MYC mRNA CTD PMID:21170416 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha multiple interactions ISO pyrvinium inhibits the reaction [PIK3CA protein modified form results in decreased expression of CCNG2 mRNA]; pyrvinium inhibits the reaction [PIK3CA protein modified form results in decreased expression of CSGALNACT1 mRNA]; pyrvinium inhibits the reaction [PIK3CA protein modified form results in decreased expression of CXCL8 mRNA]; pyrvinium inhibits the reaction [PIK3CA protein modified form results in decreased expression of HBP1 mRNA]; pyrvinium inhibits the reaction [PIK3CA protein modified form results in decreased expression of HEY1 mRNA]; pyrvinium inhibits the reaction [PIK3CA protein modified form results in decreased expression of TGFA mRNA]; pyrvinium inhibits the reaction [PIK3CA protein modified form results in increased expression of CCNE2 mRNA]; pyrvinium inhibits the reaction [PIK3CA protein modified form results in increased expression of DSCC1 mRNA]; pyrvinium inhibits the reaction [PIK3CA protein modified form results in increased expression of ENDOD1 mRNA]; pyrvinium inhibits the reaction [PIK3CA protein modified form results in increased expression of PPP2R1B mRNA] CTD PMID:27542212 NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032
JBrowse link
G Ppp2r1b protein phosphatase 2 scaffold subunit A beta multiple interactions ISO pyrvinium inhibits the reaction [PIK3CA protein modified form results in increased expression of PPP2R1B mRNA] CTD PMID:27542212 NCBI chr 8:51,195,860...51,228,442
Ensembl chr 8:51,186,717...51,228,485
JBrowse link
G Rps6 ribosomal protein S6 decreases phosphorylation
affects phosphorylation
ISO pyrvinium results in decreased phosphorylation of RPS6 protein
pyrvinium affects the phosphorylation of RPS6 protein
CTD PMID:27542212 NCBI chr 5:101,371,716...101,374,576
Ensembl chr 5:101,371,136...101,374,602
Ensembl chr 5:101,371,136...101,374,602
JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 decreases phosphorylation ISO pyrvinium results in decreased phosphorylation of RPS6KB1 protein CTD PMID:27542212 NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908
JBrowse link
G Tgfa transforming growth factor alpha multiple interactions ISO pyrvinium inhibits the reaction [PIK3CA protein modified form results in decreased expression of TGFA mRNA] CTD PMID:27542212 NCBI chr 4:118,618,043...118,700,897
Ensembl chr 4:118,618,269...118,700,894
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP pyrvinium inhibits the reaction [Glyburide promotes the reaction [Isoproterenol results in increased expression of TGFB1 protein]]; pyrvinium inhibits the reaction [Isoproterenol results in increased expression of TGFB1 protein] CTD PMID:35305975 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP pyrvinium inhibits the reaction [Glyburide promotes the reaction [Isoproterenol results in increased expression of TNF protein]]; pyrvinium inhibits the reaction [Isoproterenol results in increased expression of TNF protein] CTD PMID:35305975 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnni3 troponin I3, cardiac type multiple interactions EXP pyrvinium inhibits the reaction [Glyburide promotes the reaction [Isoproterenol results in increased expression of TNNI3 protein]]; pyrvinium inhibits the reaction [Isoproterenol results in increased expression of TNNI3 protein] CTD PMID:35305975 NCBI chr 1:69,299,900...69,303,582
Ensembl chr 1:69,299,900...69,303,580
JBrowse link
G Vegfa vascular endothelial growth factor A decreases expression ISO pyrvinium results in decreased expression of VEGFA protein CTD PMID:20116850 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
G Vim vimentin multiple interactions ISO pyrvinium inhibits the reaction [belinostat results in increased expression of VIM protein] CTD PMID:23671600 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
JBrowse link
G Wnt7a Wnt family member 7A decreases activity ISO pyrvinium results in decreased activity of WNT7A protein CTD PMID:25174399 NCBI chr 4:123,863,108...123,908,981
Ensembl chr 4:123,863,108...123,908,981
JBrowse link
G Wwtr1 WW domain containing transcription regulator 1 multiple interactions ISO pyrvinium inhibits the reaction [belinostat results in increased expression of WWTR1 protein] CTD PMID:23671600 NCBI chr 2:141,651,159...141,766,919
Ensembl chr 2:141,648,108...141,766,968
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19918
    chemical entity 19916
      molecular entity 19916
        ion 16729
          organic ion 9870
            organic cation 8917
              quinolinium ion 45
                1,1'-[1,9-bis(dimethylammonio)nonane-1,9-diyl]bis\ 0
                4-[(3-carboxy-2-hydroxy-1-naphthalenyl)methyl]-3-hydroxy-2-naphthalenecarboxylic acid 2-[2-(2,5-dimethyl-1-phenyl-3-pyrrolyl)ethyl]-N,N,1-trimethyl-6-quinolin-1-iumamine 0
                LDS 751(1+) + 0
                LSM-36456 0
                To-Pro-1(2+) + 0
                To-Pro-3(2+) + 0
                ToTo-1(4+) + 0
                ToTo-3(4+) + 0
                UCL 1684 0
                Yo-Pro-1(2+) + 0
                Yo-Pro-3(2+) + 0
                YoYo-1(4+) + 0
                YoYo-3(4+) + 0
                chloroquine(2+) 0
                cryptocyanin cation + 0
                dequalinium + 11
                hydroxychloroquine(2+) 0
                lenvatinib(1+) + 0
                pinacyanol cation + 0
                pyrvinium 37
                thiazole orange cation + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19918
    subatomic particle 19916
      composite particle 19916
        hadron 19916
          baryon 19916
            nucleon 19916
              atomic nucleus 19916
                atom 19916
                  main group element atom 19866
                    main group molecular entity 19866
                      p-block molecular entity 19866
                        carbon group molecular entity 19811
                          organic molecular entity 19806
                            organic ion 9870
                              organic cation 8917
                                quinolinium ion 45
                                  1,1'-[1,9-bis(dimethylammonio)nonane-1,9-diyl]bis\ 0
                                  4-[(3-carboxy-2-hydroxy-1-naphthalenyl)methyl]-3-hydroxy-2-naphthalenecarboxylic acid 2-[2-(2,5-dimethyl-1-phenyl-3-pyrrolyl)ethyl]-N,N,1-trimethyl-6-quinolin-1-iumamine 0
                                  LDS 751(1+) + 0
                                  LSM-36456 0
                                  To-Pro-1(2+) + 0
                                  To-Pro-3(2+) + 0
                                  ToTo-1(4+) + 0
                                  ToTo-3(4+) + 0
                                  UCL 1684 0
                                  Yo-Pro-1(2+) + 0
                                  Yo-Pro-3(2+) + 0
                                  YoYo-1(4+) + 0
                                  YoYo-3(4+) + 0
                                  chloroquine(2+) 0
                                  cryptocyanin cation + 0
                                  dequalinium + 11
                                  hydroxychloroquine(2+) 0
                                  lenvatinib(1+) + 0
                                  pinacyanol cation + 0
                                  pyrvinium 37
                                  thiazole orange cation + 0
paths to the root