CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: pentane-2,3-dione
Accession: CHEBI:52774
browse the term
Definition: An alpha-diketone that is pentane substituted at the 2- and 3-positions by oxo groups.
Synonyms: related_synonym: 2,3-Pentanedione; Acetyl propionyl; Acetylpropionyl; Formula=C5H8O2; InChI=1S/C5H8O2/c1-3-5(7)4(2)6/h3H2,1-2H3; InChIKey=TZMFJUDUGYTVRY-UHFFFAOYSA-N; SMILES=CCC(=O)C(C)=O; ethyl methyl diketone
xref: Beilstein:1699638; CAS:600-14-6; HMDB:HMDB0031598
xref_mesh: MESH:C013186
xref: PMID:23677441; PMID:24007741; PMID:24635357; Reaxys:1699638
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Adam10
ADAM metallopeptidase domain 10
increases expression
EXP
2,3-pentanedione results in increased expression of ADAM10 mRNA
CTD
PMID:25710175
NCBI chr 8:71,346,008...71,477,889
Ensembl chr 8:71,345,837...71,477,889
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Adam19
ADAM metallopeptidase domain 19
increases expression
EXP
2,3-pentanedione results in increased expression of ADAM19 mRNA
CTD
PMID:25710175
NCBI chr10:30,491,362...30,583,115
Ensembl chr10:30,491,405...30,583,105
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Adam8
ADAM metallopeptidase domain 8
decreases expression
EXP
2,3-pentanedione results in decreased expression of ADAM8 mRNA
CTD
PMID:25710175
NCBI chr 1:194,776,559...194,789,330
Ensembl chr 1:194,770,060...194,788,801
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Akap5
A-kinase anchoring protein 5
increases expression
EXP
2,3-pentanedione results in increased expression of AKAP5 mRNA
CTD
PMID:25710175
NCBI chr 6:95,051,527...95,061,075
Ensembl chr 6:95,051,537...95,061,578
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Akr1b1
aldo-keto reductase family 1 member B1
increases reduction multiple interactions
ISO
AKR1B1 protein results in increased reduction of 2,3-pentanedione [AKR1B1 protein results in increased reduction of 2,3-pentanedione] which results in increased chemical synthesis of Pentanones
CTD
PMID:23295224
NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157
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Akr1b10
aldo-keto reductase family 1 member B10
increases reduction multiple interactions
ISO
AKR1B10 protein results in increased reduction of 2,3-pentanedione [AKR1B10 protein results in increased reduction of 2,3-pentanedione] which results in increased chemical synthesis of Pentanones
CTD
PMID:23295224
NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852
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Aldh1a3
aldehyde dehydrogenase 1 family, member A3
increases expression
ISO
2,3-pentanedione results in increased expression of ALDH1A3 mRNA
CTD
PMID:30710127
NCBI chr 1:119,982,272...120,017,416
Ensembl chr 1:119,982,277...120,017,436
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Angptl4
angiopoietin-like 4
increases expression
EXP
2,3-pentanedione results in increased expression of ANGPTL4 mRNA
CTD
PMID:25710175
NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519
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Apln
apelin
increases expression
EXP
2,3-pentanedione results in increased expression of APLN mRNA
CTD
PMID:25710175
NCBI chr X:127,180,801...127,213,567
Ensembl chr X:127,203,823...127,213,391
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Arhgap17
Rho GTPase activating protein 17
increases expression
EXP
2,3-pentanedione results in increased expression of ARHGAP17 mRNA
CTD
PMID:25710175
NCBI chr 1:177,807,579...177,897,027
Ensembl chr 1:177,807,583...177,896,854
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Bcat1
branched chain amino acid transaminase 1
increases expression
EXP
2,3-pentanedione results in increased expression of BCAT1 mRNA
CTD
PMID:25710175
NCBI chr 4:177,964,834...178,046,573
Ensembl chr 4:177,964,834...178,046,597
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Bmp3
bone morphogenetic protein 3
decreases expression
EXP
2,3-pentanedione results in decreased expression of BMP3 mRNA
CTD
PMID:25710175
NCBI chr14:10,712,489...10,737,153
Ensembl chr14:10,712,489...10,737,153
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C9
complement C9
decreases expression
EXP
2,3-pentanedione results in decreased expression of C9 mRNA
CTD
PMID:25710175
NCBI chr 2:55,573,094...55,621,345
Ensembl chr 2:55,572,992...55,621,338
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Cc2d2a
coiled-coil and C2 domain containing 2A
decreases expression
ISO
2,3-pentanedione results in decreased expression of CC2D2A mRNA
CTD
PMID:30710127
NCBI chr14:67,349,004...67,435,883
Ensembl chr14:67,351,353...67,435,949
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Ccn2
cellular communication network factor 2
increases expression
EXP
2,3-pentanedione results in increased expression of CCN2 mRNA
CTD
PMID:25710175
NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734
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Ccn4
cellular communication network factor 4
increases expression
EXP
2,3-pentanedione results in increased expression of CCN4 mRNA
CTD
PMID:25710175
NCBI chr 7:98,645,238...98,677,253
Ensembl chr 7:98,645,182...98,677,248
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Cd36
CD36 molecule
increases expression
EXP
2,3-pentanedione results in increased expression of CD36 mRNA
CTD
PMID:25710175
NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
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Cdc20b
cell division cycle 20B
decreases expression
ISO
2,3-pentanedione results in decreased expression of CDC20B mRNA
CTD
PMID:30710127
NCBI chr 2:44,688,349...44,738,056
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Cdhr4
cadherin-related family member 4
decreases expression
EXP
2,3-pentanedione results in decreased expression of CDHR4 mRNA
CTD
PMID:25710175
NCBI chr 8:108,682,594...108,690,358
Ensembl chr 8:108,682,613...108,690,367
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Ces1d
carboxylesterase 1D
decreases expression
EXP
2,3-pentanedione results in decreased expression of CES1D mRNA
CTD
PMID:25710175
NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035
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Cfap221
cilia and flagella associated protein 221
decreases expression
ISO
2,3-pentanedione results in decreased expression of CFAP221 mRNA
CTD
PMID:30710127
NCBI chr13:31,046,550...31,118,141
Ensembl chr13:31,046,535...31,116,899
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Cfap70
cilia and flagella associated protein 70
decreases expression
ISO
2,3-pentanedione results in decreased expression of CFAP70 mRNA
CTD
PMID:30710127
NCBI chr15:3,852,381...3,918,036
Ensembl chr15:3,852,509...3,918,014
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Cldn18
claudin 18
increases expression
EXP
2,3-pentanedione results in increased expression of CLDN18 mRNA
CTD
PMID:25710175
NCBI chr 8:100,246,499...100,265,797
Ensembl chr 8:100,247,633...100,273,351
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Clic5
chloride intracellular channel 5
increases expression
EXP
2,3-pentanedione results in increased expression of CLIC5 mRNA
CTD
PMID:25710175
NCBI chr 9:16,710,980...16,813,502
Ensembl chr 9:16,710,980...16,813,427
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Cma1
chymase 1
increases expression
EXP
2,3-pentanedione results in increased expression of CMA1 mRNA
CTD
PMID:25710175
NCBI chr15:29,417,451...29,420,233
Ensembl chr15:29,417,451...29,420,233
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Col12a1
collagen type XII alpha 1 chain
increases expression
EXP
2,3-pentanedione results in increased expression of COL12A1 mRNA
CTD
PMID:25710175
NCBI chr 8:80,547,592...80,665,665
Ensembl chr 8:80,547,593...80,665,686
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Col13a1
collagen type XIII alpha 1 chain
decreases expression
EXP
2,3-pentanedione results in decreased expression of COL13A1 mRNA
CTD
PMID:25710175
NCBI chr20:29,783,965...29,924,116
Ensembl chr20:29,783,965...29,924,032
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Col14a1
collagen type XIV alpha 1 chain
increases expression
EXP
2,3-pentanedione results in increased expression of COL14A1 mRNA
CTD
PMID:25710175
NCBI chr 7:86,722,093...86,937,215
Ensembl chr 7:86,722,094...86,937,214
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Col18a1
collagen type XVIII alpha 1 chain
increases expression
EXP
2,3-pentanedione results in increased expression of COL18A1 mRNA
CTD
PMID:25710175
NCBI chr20:11,474,104...11,582,593
Ensembl chr20:11,474,104...11,582,593
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Col1a2
collagen type I alpha 2 chain
increases expression
EXP
2,3-pentanedione results in increased expression of COL1A2 mRNA
CTD
PMID:25710175
NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867
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Col4a1
collagen type IV alpha 1 chain
increases expression
EXP
2,3-pentanedione results in increased expression of COL4A1 mRNA
CTD
PMID:25710175
NCBI chr16:78,183,533...78,294,412
Ensembl chr16:78,183,533...78,294,412
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Col5a1
collagen type V alpha 1 chain
increases expression
EXP
2,3-pentanedione results in increased expression of COL5A1 mRNA
CTD
PMID:25710175
NCBI chr 3:11,208,429...11,356,715
Ensembl chr 3:11,208,512...11,354,588
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Col5a2
collagen type V alpha 2 chain
increases expression
EXP
2,3-pentanedione results in increased expression of COL5A2 mRNA
CTD
PMID:25710175
NCBI chr 9:47,448,741...47,598,134
Ensembl chr 9:47,448,736...47,598,154
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Col5a3
collagen type V alpha 3 chain
increases expression
EXP
2,3-pentanedione results in increased expression of COL5A3 mRNA
CTD
PMID:25710175
NCBI chr 8:19,304,564...19,349,809
Ensembl chr 8:19,304,571...19,349,853
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Col6a2
collagen type VI alpha 2 chain
increases expression
EXP
2,3-pentanedione results in increased expression of COL6A2 mRNA
CTD
PMID:25710175
NCBI chr20:12,021,676...12,049,425
Ensembl chr20:12,021,767...12,057,564
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Cpxm2
carboxypeptidase X (M14 family), member 2
decreases expression
ISO
2,3-pentanedione results in decreased expression of CPXM2 mRNA
CTD
PMID:30710127
NCBI chr 1:186,836,797...186,947,222
Ensembl chr 1:186,836,797...186,947,220
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Crabp2
cellular retinoic acid binding protein 2
increases expression
EXP
2,3-pentanedione results in increased expression of CRABP2 mRNA
CTD
PMID:25710175
NCBI chr 2:173,417,004...173,421,352
Ensembl chr 2:173,416,857...173,421,379
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Csf3
colony stimulating factor 3
decreases expression
ISO
2,3-pentanedione results in decreased expression of CSF3 mRNA
CTD
PMID:30710127
NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603
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Cthrc1
collagen triple helix repeat containing 1
increases expression
EXP
2,3-pentanedione results in increased expression of CTHRC1 mRNA
CTD
PMID:25710175
NCBI chr 7:70,122,474...70,132,756
Ensembl chr 7:70,122,474...70,132,756
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Cx3cr1
C-X3-C motif chemokine receptor 1
increases expression
EXP
2,3-pentanedione results in increased expression of CX3CR1 mRNA
CTD
PMID:25710175
NCBI chr 8:119,785,726...119,799,431
Ensembl chr 8:119,782,595...119,800,014
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Cxcl1
C-X-C motif chemokine ligand 1
decreases expression
EXP
2,3-pentanedione results in decreased expression of CXCL1 mRNA
CTD
PMID:25710175
NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215
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Cxcl3
C-X-C motif chemokine ligand 3
decreases expression
EXP
2,3-pentanedione results in decreased expression of CXCL3 mRNA
CTD
PMID:25710175
NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511
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Cxcr4
C-X-C motif chemokine receptor 4
decreases expression increases expression
EXP
2,3-pentanedione results in decreased expression of CXCR4 mRNA 2,3-pentanedione results in increased expression of CXCR4 mRNA
CTD
PMID:25710175
NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
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Cyp2a3
cytochrome P450, family 2, subfamily a, polypeptide 3
decreases expression
EXP
2,3-pentanedione results in decreased expression of CYP2A3 mRNA
CTD
PMID:25710175
NCBI chr 1:82,171,914...82,179,980
Ensembl chr 1:82,169,949...82,179,979
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Cyp2b1
cytochrome P450, family 2, subfamily b, polypeptide 1
decreases expression
EXP
2,3-pentanedione results in decreased expression of CYP2B1 mRNA
CTD
PMID:25710175
NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
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Cyp2f4
cytochrome P450, family 2, subfamily f, polypeptide 4
decreases expression
EXP
2,3-pentanedione results in decreased expression of CYP2F4 mRNA
CTD
PMID:25710175
NCBI chr 1:82,416,107...82,429,897
Ensembl chr 1:82,416,130...82,429,896
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Cyp4b1
cytochrome P450, family 4, subfamily b, polypeptide 1
decreases expression
EXP
2,3-pentanedione results in decreased expression of CYP4B1 mRNA
CTD
PMID:25710175
NCBI chr 5:129,139,019...129,176,860
Ensembl chr 5:129,139,038...129,156,348
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Dhrs9
dehydrogenase/reductase 9
increases expression
ISO
2,3-pentanedione results in increased expression of DHRS9 mRNA
CTD
PMID:30710127
NCBI chr 3:54,147,834...54,170,052
Ensembl chr 3:54,147,803...54,220,241
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Dmrt2
doublesex and mab-3 related transcription factor 2
decreases expression
EXP
2,3-pentanedione results in decreased expression of DMRT2 mRNA
CTD
PMID:25710175
NCBI chr 1:223,317,543...223,324,131
Ensembl chr 1:223,317,642...223,324,131
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Dnaaf1
dynein, axonemal, assembly factor 1
decreases expression
ISO
2,3-pentanedione results in decreased expression of DNAAF1 mRNA
CTD
PMID:30710127
NCBI chr19:47,624,534...47,652,314
Ensembl chr19:47,624,181...47,652,313
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Dnah12
dynein, axonemal, heavy chain 12
decreases expression
ISO
2,3-pentanedione results in decreased expression of DNAH12 mRNA
CTD
PMID:30710127
NCBI chr16:1,936,354...2,092,663
Ensembl chr16:1,937,817...2,092,664
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Dnah3
dynein, axonemal, heavy chain 3
decreases expression
ISO
2,3-pentanedione results in decreased expression of DNAH3 mRNA
CTD
PMID:30710127
NCBI chr 1:174,305,929...174,479,490
Ensembl chr 1:174,306,644...174,479,474
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Dnah6
dynein, axonemal, heavy chain 6
decreases expression
ISO
2,3-pentanedione results in decreased expression of DNAH6 mRNA
CTD
PMID:30710127
NCBI chr 4:105,064,123...105,284,361
Ensembl chr 4:105,064,125...105,284,376
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Dnai1
dynein, axonemal, intermediate chain 1
decreases expression
ISO
2,3-pentanedione results in decreased expression of DNAI1 mRNA
CTD
PMID:30710127
NCBI chr 5:56,730,179...56,800,926
Ensembl chr 5:56,730,179...56,800,925
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Egfr
epidermal growth factor receptor
increases expression
EXP
2,3-pentanedione results in increased expression of EGFR mRNA
CTD
PMID:25710175
NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
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Egr2
early growth response 2
increases expression
EXP
2,3-pentanedione results in increased expression of EGR2 mRNA
CTD
PMID:25710175
NCBI chr20:21,051,270...21,056,322
Ensembl chr20:21,051,277...21,055,562
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Fbln1
fibulin 1
decreases expression
EXP
2,3-pentanedione results in decreased expression of FBLN1 mRNA
CTD
PMID:25710175
NCBI chr 7:116,310,582...116,390,075
Ensembl chr 7:116,310,582...116,390,075
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Fbn1
fibrillin 1
increases expression
EXP
2,3-pentanedione results in increased expression of FBN1 mRNA
CTD
PMID:25710175
NCBI chr 3:112,554,257...112,750,835
Ensembl chr 3:112,554,925...112,750,889
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Fgfr2
fibroblast growth factor receptor 2
decreases expression
EXP
2,3-pentanedione results in decreased expression of FGFR2 mRNA
CTD
PMID:25710175
NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626
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Fgfr3
fibroblast growth factor receptor 3
decreases expression
EXP
2,3-pentanedione results in decreased expression of FGFR3 mRNA
CTD
PMID:25710175
NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341
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Fmo2
flavin containing dimethylaniline monoxygenase 2
decreases expression
EXP
2,3-pentanedione results in decreased expression of FMO2 mRNA
CTD
PMID:25710175
NCBI chr13:75,221,149...75,244,377
Ensembl chr13:75,224,402...75,244,308
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Fn1
fibronectin 1
increases expression
EXP
2,3-pentanedione results in increased expression of FN1 mRNA
CTD
PMID:25710175
NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
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Fndc3b
fibronectin type III domain containing 3B
decreases expression
EXP
2,3-pentanedione results in decreased expression of FNDC3B mRNA
CTD
PMID:25710175
NCBI chr 2:110,311,439...110,617,504
Ensembl chr 2:110,312,694...110,547,830
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Gad1
glutamate decarboxylase 1
decreases expression
EXP
2,3-pentanedione results in decreased expression of GAD1 mRNA
CTD
PMID:25710175
NCBI chr 3:55,369,704...55,410,335
Ensembl chr 3:55,369,704...55,410,333
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Gas6
growth arrest specific 6
increases expression
EXP
2,3-pentanedione results in increased expression of GAS6 mRNA
CTD
PMID:25710175
NCBI chr16:76,045,430...76,075,904
Ensembl chr16:76,045,426...76,075,904
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Ghitm
growth hormone inducible transmembrane protein
decreases expression
EXP
2,3-pentanedione results in decreased expression of GHITM mRNA
CTD
PMID:25710175
NCBI chr16:12,885,551...12,897,887
Ensembl chr16:12,885,553...12,897,879
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Gpr155
G protein-coupled receptor 155
decreases expression
EXP
2,3-pentanedione results in decreased expression of GPR155 mRNA
CTD
PMID:25710175
NCBI chr 3:58,216,422...58,270,350
Ensembl chr 3:58,216,423...58,270,275
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Gpx2
glutathione peroxidase 2
increases expression
ISO
2,3-pentanedione results in increased expression of GPX2 mRNA
CTD
PMID:30710127
NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877
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Grb10
growth factor receptor bound protein 10
increases expression
EXP
2,3-pentanedione results in increased expression of GRB10 mRNA
CTD
PMID:25710175
NCBI chr14:86,495,051...86,602,800
Ensembl chr14:86,495,054...86,602,806
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Gsta5
glutathione S-transferase alpha 5
decreases expression
EXP
2,3-pentanedione results in decreased expression of GSTA5 mRNA
CTD
PMID:25710175
NCBI chr 8:79,105,561...79,117,472
Ensembl chr 8:79,105,661...79,117,472
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Hap1
huntingtin-associated protein 1
decreases expression
EXP
2,3-pentanedione results in decreased expression of HAP1 mRNA
CTD
PMID:25710175
NCBI chr10:85,277,890...85,286,126
Ensembl chr10:85,277,890...85,286,126
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Has2
hyaluronan synthase 2
increases expression
EXP
2,3-pentanedione results in increased expression of HAS2 mRNA
CTD
PMID:25710175
NCBI chr 7:88,113,326...88,139,337
Ensembl chr 7:88,113,326...88,128,933
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Hbegf
heparin-binding EGF-like growth factor
increases expression
EXP
2,3-pentanedione results in increased expression of HBEGF mRNA
CTD
PMID:25710175
NCBI chr18:28,106,284...28,116,167
Ensembl chr18:28,105,760...28,116,441
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Hdac10
histone deacetylase 10
increases expression
EXP
2,3-pentanedione results in increased expression of HDAC10 mRNA
CTD
PMID:25710175
NCBI chr 7:120,199,126...120,205,850
Ensembl chr 7:120,199,129...120,204,228
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Igf1
insulin-like growth factor 1
increases expression
EXP
2,3-pentanedione results in increased expression of IGF1 mRNA
CTD
PMID:25710175
NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
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Igf2bp2
insulin-like growth factor 2 mRNA binding protein 2
increases expression
EXP
2,3-pentanedione results in increased expression of IGF2BP2 mRNA
CTD
PMID:25710175
NCBI chr11:78,874,402...78,974,392
Ensembl chr11:78,874,414...78,974,377
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Igfbp4
insulin-like growth factor binding protein 4
increases expression
EXP
2,3-pentanedione results in increased expression of IGFBP4 mRNA
CTD
PMID:25710175
NCBI chr10:83,995,253...84,007,272
Ensembl chr10:83,989,591...84,007,225
G
Igfbp5
insulin-like growth factor binding protein 5
decreases expression
EXP
2,3-pentanedione results in decreased expression of IGFBP5 mRNA
CTD
PMID:25710175
NCBI chr 9:74,452,371...74,464,953
Ensembl chr 9:74,448,382...74,465,156
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Il18
interleukin 18
increases expression
EXP
2,3-pentanedione results in increased expression of IL18 mRNA
CTD
PMID:25710175
NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
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Il1a
interleukin 1 alpha
increases expression
EXP
2,3-pentanedione results in increased expression of IL1A mRNA
CTD
PMID:25710175
NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
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Il1rn
interleukin 1 receptor antagonist
increases expression
EXP
2,3-pentanedione results in increased expression of IL1RN mRNA
CTD
PMID:25710175
NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445
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Il24
interleukin 24
increases expression
EXP
2,3-pentanedione results in increased expression of IL24 mRNA
CTD
PMID:25710175
NCBI chr13:42,353,089...42,358,487
Ensembl chr13:42,353,090...42,358,487
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Il33
interleukin 33
increases expression decreases expression
EXP ISO
2,3-pentanedione results in increased expression of IL33 mRNA 2,3-pentanedione results in decreased expression of IL33 mRNA
CTD
PMID:25710175 PMID:30710127
NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373
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Inhba
inhibin subunit beta A
increases expression
EXP
2,3-pentanedione results in increased expression of INHBA mRNA
CTD
PMID:25710175
NCBI chr17:49,091,635...49,111,573
Ensembl chr17:49,095,920...49,108,982
G
Irak1bp1
interleukin-1 receptor-associated kinase 1 binding protein 1
decreases expression
EXP
2,3-pentanedione results in decreased expression of IRAK1BP1 mRNA
CTD
PMID:25710175
NCBI chr 8:83,731,512...83,748,289
Ensembl chr 8:83,731,507...83,748,289
G
Itga5
integrin subunit alpha 5
increases expression
EXP
2,3-pentanedione results in increased expression of ITGA5 mRNA
CTD
PMID:25710175
NCBI chr 7:134,478,963...134,502,837
Ensembl chr 7:134,478,968...134,502,837
G
Itga6
integrin subunit alpha 6
increases expression
EXP
2,3-pentanedione results in increased expression of ITGA6 mRNA
CTD
PMID:25710175
NCBI chr 3:56,604,512...56,689,428
Ensembl chr 3:56,617,268...56,689,428
G
Itgb1
integrin subunit beta 1
increases expression
EXP
2,3-pentanedione results in increased expression of ITGB1 mRNA
CTD
PMID:25710175
NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195
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Itgb3
integrin subunit beta 3
increases expression
EXP
2,3-pentanedione results in increased expression of ITGB3 mRNA
CTD
PMID:25710175
NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679
G
Klhl38
kelch-like family member 38
decreases expression
EXP
2,3-pentanedione results in decreased expression of KLHL38 mRNA
CTD
PMID:25710175
NCBI chr 7:89,854,015...89,864,352
Ensembl chr 7:89,855,148...89,864,276
G
Krt13
keratin 13
increases expression
ISO
2,3-pentanedione results in increased expression of KRT13 mRNA
CTD
PMID:30710127
NCBI chr10:85,051,887...85,056,099
Ensembl chr10:85,051,889...85,056,084
G
Krt14
keratin 14
increases expression
ISO
2,3-pentanedione results in increased expression of KRT14 mRNA
CTD
PMID:30710127
NCBI chr10:85,137,786...85,142,054
Ensembl chr10:85,066,802...85,171,799
G
Krt16
keratin 16
increases expression
ISO
2,3-pentanedione results in increased expression of KRT16 mRNA
CTD
PMID:30710127
NCBI chr10:85,168,357...85,171,816
Ensembl chr10:85,066,802...85,171,799
G
Krt4
keratin 4
increases expression
ISO
2,3-pentanedione results in increased expression of KRT4 mRNA
CTD
PMID:30710127
NCBI chr 7:133,046,067...133,052,027
Ensembl chr 7:133,046,515...133,052,019
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Lamb3
laminin subunit beta 3
increases expression
EXP
2,3-pentanedione results in increased expression of LAMB3 mRNA
CTD
PMID:25710175
NCBI chr13:104,833,810...104,875,405
Ensembl chr13:104,833,873...104,875,405
G
Lamc2
laminin subunit gamma 2
increases expression
EXP
2,3-pentanedione results in increased expression of LAMC2 mRNA
CTD
PMID:25710175
NCBI chr13:65,284,664...65,344,164
Ensembl chr13:65,284,664...65,344,200
G
Lamc3
laminin subunit gamma 3
decreases expression
EXP
2,3-pentanedione results in decreased expression of LAMC3 mRNA
CTD
PMID:25710175
NCBI chr 3:15,165,220...15,226,697
Ensembl chr 3:15,165,220...15,226,697
G
Lgi1
leucine-rich, glioma inactivated 1
decreases expression
EXP
2,3-pentanedione results in decreased expression of LGI1 mRNA
CTD
PMID:25710175
NCBI chr 1:236,043,269...236,084,617
Ensembl chr 1:236,042,954...236,084,616
G
Lox
lysyl oxidase
increases expression
EXP
2,3-pentanedione results in increased expression of LOX mRNA
CTD
PMID:25710175
NCBI chr18:45,964,544...45,977,431
Ensembl chr18:45,967,343...46,041,477
G
Loxl2
lysyl oxidase-like 2
increases expression
EXP
2,3-pentanedione results in increased expression of LOXL2 mRNA
CTD
PMID:25710175
NCBI chr15:44,683,449...44,773,067
Ensembl chr15:44,683,880...44,773,067
G
Lrp10
LDL receptor related protein 10
increases expression
EXP
2,3-pentanedione results in increased expression of LRP10 mRNA
CTD
PMID:25710175
NCBI chr15:27,921,335...27,927,507
Ensembl chr15:27,920,259...27,927,505
G
Mmp14
matrix metallopeptidase 14
increases expression
EXP
2,3-pentanedione results in increased expression of MMP14 mRNA
CTD
PMID:25710175
NCBI chr15:27,887,795...27,897,020
Ensembl chr15:27,887,727...27,899,864
G
Mmp2
matrix metallopeptidase 2
increases expression
EXP
2,3-pentanedione results in increased expression of MMP2 mRNA
CTD
PMID:25710175
NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
G
Mmp24
matrix metallopeptidase 24
decreases expression
EXP
2,3-pentanedione results in decreased expression of MMP24 mRNA
CTD
PMID:25710175
NCBI chr 3:144,279,096...144,323,572
Ensembl chr 3:144,279,096...144,323,572
G
Ngf
nerve growth factor
increases expression
EXP
2,3-pentanedione results in increased expression of NGF mRNA
CTD
PMID:25710175
NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452
G
Nkain1
Sodium/potassium transporting ATPase interacting 1
increases expression
EXP
2,3-pentanedione results in increased expression of NKAIN1 mRNA
CTD
PMID:25710175
NCBI chr 5:142,747,702...142,792,665
Ensembl chr 5:142,747,505...142,791,863
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Nog
noggin
increases expression
EXP
2,3-pentanedione results in increased expression of NOG mRNA
CTD
PMID:25710175
NCBI chr10:74,128,712...74,130,339
Ensembl chr10:74,128,712...74,130,339
G
Nrg1
neuregulin 1
increases expression
EXP
2,3-pentanedione results in increased expression of NRG1 mRNA
CTD
PMID:25710175
NCBI chr16:59,250,658...60,304,519
Ensembl chr16:59,250,854...60,296,884
G
Papss2
3'-phosphoadenosine 5'-phosphosulfate synthase 2
decreases expression
ISO
2,3-pentanedione results in decreased expression of PAPSS2 mRNA
CTD
PMID:30710127
NCBI chr 1:230,454,314...230,539,332
Ensembl chr 1:230,454,426...230,539,331
G
Pdgfrb
platelet derived growth factor receptor beta
increases expression
EXP
2,3-pentanedione results in increased expression of PDGFRB mRNA
CTD
PMID:25710175
NCBI chr18:54,499,962...54,538,840
Ensembl chr18:54,499,964...54,538,843
G
Plat
plasminogen activator, tissue type
increases expression
EXP
2,3-pentanedione results in increased expression of PLAT mRNA
CTD
PMID:25710175
NCBI chr16:69,240,582...69,265,177
Ensembl chr16:69,240,585...69,268,223
G
Plau
plasminogen activator, urokinase
increases expression
EXP
2,3-pentanedione results in increased expression of PLAU mRNA
CTD
PMID:25710175
NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775
G
Plaur
plasminogen activator, urokinase receptor
increases expression
EXP
2,3-pentanedione results in increased expression of PLAUR mRNA
CTD
PMID:25710175
NCBI chr 1:80,053,440...80,068,384
Ensembl chr 1:80,050,324...80,068,595
G
Plod2
procollagen lysine, 2-oxoglutarate 5-dioxygenase 2
increases expression
EXP
2,3-pentanedione results in increased expression of PLOD2 mRNA
CTD
PMID:25710175
NCBI chr 8:93,084,548...93,167,255
Ensembl chr 8:93,084,513...93,167,255
G
Pon1
paraoxonase 1
decreases expression
EXP
2,3-pentanedione results in decreased expression of PON1 mRNA
CTD
PMID:25710175
NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360
G
Ppara
peroxisome proliferator activated receptor alpha
decreases expression
EXP
2,3-pentanedione results in decreased expression of PPARA mRNA
CTD
PMID:25710175
NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
G
Prom1
prominin 1
decreases expression
ISO
2,3-pentanedione results in decreased expression of PROM1 mRNA
CTD
PMID:30710127
NCBI chr14:66,989,545...67,094,534
Ensembl chr14:66,990,160...67,094,527
G
Prss22
serine protease 22
increases expression
EXP
2,3-pentanedione results in increased expression of PRSS22 mRNA
CTD
PMID:25710175
NCBI chr10:13,029,153...13,033,863
Ensembl chr10:13,029,153...13,033,863
G
Ptgs2
prostaglandin-endoperoxide synthase 2
decreases expression
ISO
2,3-pentanedione results in decreased expression of PTGS2 mRNA
CTD
PMID:30710127
NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
G
Pthlh
parathyroid hormone-like hormone
decreases expression
ISO
2,3-pentanedione results in decreased expression of PTHLH mRNA
CTD
PMID:30710127
NCBI chr 4:180,188,792...180,199,847
Ensembl chr 4:180,188,792...180,199,847
G
Rasgrp1
RAS guanyl releasing protein 1
decreases expression
EXP
2,3-pentanedione results in decreased expression of RASGRP1 mRNA
CTD
PMID:25710175
NCBI chr 3:104,168,549...104,230,107
Ensembl chr 3:104,170,013...104,230,056
G
S100a1
S100 calcium binding protein A1
decreases expression
EXP
2,3-pentanedione results in decreased expression of S100A1 mRNA
CTD
PMID:25710175
NCBI chr 2:175,993,922...175,998,765
Ensembl chr 2:175,993,922...175,999,544
G
S1pr1
sphingosine-1-phosphate receptor 1
decreases expression
EXP
2,3-pentanedione results in decreased expression of S1PR1 mRNA
CTD
PMID:25710175
NCBI chr 2:203,624,752...203,629,110
Ensembl chr 2:203,621,587...203,629,681
G
Sbp
spermine binding protein
decreases expression
EXP
2,3-pentanedione results in decreased expression of SBP mRNA
CTD
PMID:25710175
NCBI chr10:12,946,036...12,968,439
Ensembl chr10:12,946,036...12,968,439
G
Scgb1a1
secretoglobin family 1A member 1
increases expression
ISO
2,3-pentanedione results in increased expression of SCGB1A1 mRNA
CTD
PMID:30710127
NCBI chr 1:205,977,060...205,980,610
Ensembl chr 1:205,977,060...205,980,610
G
Sec14l3
SEC14-like lipid binding 3
decreases expression
EXP
2,3-pentanedione results in decreased expression of SEC14L3 mRNA
CTD
PMID:25710175
NCBI chr14:78,944,568...78,955,608
Ensembl chr14:78,912,750...78,956,099
G
Serpinb5
serpin family B member 5
decreases expression
EXP
2,3-pentanedione results in decreased expression of SERPINB5 mRNA
CTD
PMID:25710175
NCBI chr13:22,985,557...23,005,756
Ensembl chr13:22,985,557...23,005,756
G
Serpine1
serpin family E member 1
increases expression
EXP
2,3-pentanedione results in increased expression of SERPINE1 mRNA
CTD
PMID:25710175
NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
G
Serpinf1
serpin family F member 1
increases expression
EXP
2,3-pentanedione results in increased expression of SERPINF1 mRNA
CTD
PMID:25710175
NCBI chr10:60,250,198...60,262,593
Ensembl chr10:60,249,708...60,262,646
G
Serping1
serpin family G member 1
increases expression
EXP
2,3-pentanedione results in increased expression of SERPING1 mRNA
CTD
PMID:25710175
NCBI chr 3:69,842,726...69,852,583
Ensembl chr 3:69,842,739...69,852,034
G
Serpinh1
serpin family H member 1
increases expression
EXP
2,3-pentanedione results in increased expression of SERPINH1 mRNA
CTD
PMID:25710175
NCBI chr 1:153,643,500...153,650,853
Ensembl chr 1:153,643,510...153,650,801
G
Slc15a1
solute carrier family 15 member 1
increases expression
EXP
2,3-pentanedione results in increased expression of SLC15A1 mRNA
CTD
PMID:25710175
NCBI chr15:98,537,641...98,582,544
Ensembl chr15:98,537,641...98,582,545
G
Slc15a2
solute carrier family 15 member 2
decreases expression
EXP
2,3-pentanedione results in decreased expression of SLC15A2 mRNA
CTD
PMID:25710175
NCBI chr11:64,014,182...64,043,228
Ensembl chr11:64,014,182...64,043,225
G
Slc23a1
solute carrier family 23 member 1
decreases expression
EXP
2,3-pentanedione results in decreased expression of SLC23A1 mRNA
CTD
PMID:25710175
NCBI chr18:27,214,940...27,230,564
Ensembl chr18:27,216,281...27,230,697
G
Sorcs2
sortilin-related VPS10 domain containing receptor 2
decreases expression
ISO
2,3-pentanedione results in decreased expression of SORCS2 mRNA
CTD
PMID:30710127
NCBI chr14:74,371,089...74,735,943
Ensembl chr14:74,371,415...74,735,943
G
Sorl1
sortilin related receptor 1
decreases expression
EXP
2,3-pentanedione results in decreased expression of SORL1 mRNA
CTD
PMID:25710175
NCBI chr 8:42,341,704...42,504,435
Ensembl chr 8:42,341,704...42,504,513
G
Spag17
sperm associated antigen 17
decreases expression
ISO
2,3-pentanedione results in decreased expression of SPAG17 mRNA
CTD
PMID:30710127
NCBI chr 2:187,264,004...187,511,061
Ensembl chr 2:187,264,009...187,510,501
G
Spon1
spondin 1
increases expression
EXP
2,3-pentanedione results in increased expression of SPON1 mRNA
CTD
PMID:25710175
NCBI chr 1:167,929,049...168,228,239
Ensembl chr 1:167,928,972...168,228,226
G
Spp1
secreted phosphoprotein 1
increases expression
EXP
2,3-pentanedione results in increased expression of SPP1 mRNA
CTD
PMID:25710175
NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162
G
Spr
sepiapterin reductase
decreases expression
EXP
2,3-pentanedione results in decreased expression of SPR mRNA
CTD
PMID:25710175
NCBI chr 4:117,671,948...117,676,292
Ensembl chr 4:117,671,949...117,675,678
G
Stra6
signaling receptor and transporter of retinol STRA6
decreases expression
EXP
2,3-pentanedione results in decreased expression of STRA6 mRNA
CTD
PMID:25710175
NCBI chr 8:58,548,899...58,568,861
Ensembl chr 8:58,549,736...58,568,860
G
Tekt1
tektin 1
decreases expression
ISO
2,3-pentanedione results in decreased expression of TEKT1 mRNA
CTD
PMID:30710127
NCBI chr10:56,952,164...56,980,572
Ensembl chr10:56,952,167...56,980,572
G
Tgfb2
transforming growth factor, beta 2
increases expression
EXP
2,3-pentanedione results in increased expression of TGFB2 mRNA
CTD
PMID:25710175
NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405
G
Tgfbi
transforming growth factor, beta induced
increases expression
EXP
2,3-pentanedione results in increased expression of TGFBI mRNA
CTD
PMID:25710175
NCBI chr17:7,955,603...7,984,903
Ensembl chr17:7,955,603...7,985,240
G
Tgm1
transglutaminase 1
increases expression
EXP
2,3-pentanedione results in increased expression of TGM1 mRNA
CTD
PMID:25710175
NCBI chr15:29,191,039...29,206,000
Ensembl chr15:29,191,041...29,204,523
G
Thbs2
thrombospondin 2
increases expression
EXP
2,3-pentanedione results in increased expression of THBS2 mRNA
CTD
PMID:25710175
NCBI chr 1:55,670,394...55,699,789
Ensembl chr 1:55,670,394...55,699,789
G
Thbs4
thrombospondin 4
decreases expression
EXP
2,3-pentanedione results in decreased expression of THBS4 mRNA
CTD
PMID:25710175
NCBI chr 2:23,983,158...24,025,289
Ensembl chr 2:23,983,158...24,026,313
G
Timp1
TIMP metallopeptidase inhibitor 1
increases expression
EXP
2,3-pentanedione results in increased expression of TIMP1 mRNA
CTD
PMID:25710175
NCBI chr X:1,212,969...1,217,714
Ensembl chr X:1,212,972...1,217,664
G
Timp2
TIMP metallopeptidase inhibitor 2
increases expression
EXP
2,3-pentanedione results in increased expression of TIMP2 mRNA
CTD
PMID:25710175
NCBI chr10:103,541,199...103,590,611
Ensembl chr10:103,531,505...103,590,611
G
Timp4
TIMP metallopeptidase inhibitor 4
decreases expression
EXP
2,3-pentanedione results in decreased expression of TIMP4 mRNA
CTD
PMID:25710175
NCBI chr 4:148,306,021...148,312,558
Ensembl chr 4:148,304,490...148,312,558
G
Tlr2
toll-like receptor 2
decreases expression
EXP
2,3-pentanedione results in decreased expression of TLR2 mRNA
CTD
PMID:25710175
NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630
G
Tmem178a
transmembrane protein 178A
increases expression
EXP
2,3-pentanedione results in increased expression of TMEM178 mRNA
CTD
PMID:25710175
NCBI chr 6:14,004,629...14,063,677
Ensembl chr 6:14,004,630...14,063,549
G
Tnc
tenascin C
increases expression
EXP
2,3-pentanedione results in increased expression of TNC mRNA
CTD
PMID:25710175
NCBI chr 5:77,375,851...77,460,712
Ensembl chr 5:77,375,851...77,460,624
G
Tnfaip6
TNF alpha induced protein 6
increases expression
EXP
2,3-pentanedione results in increased expression of TNFAIP6 mRNA
CTD
PMID:25710175
NCBI chr 3:36,502,250...36,521,652
Ensembl chr 3:36,502,188...36,521,649
G
Tnfrsf12a
TNF receptor superfamily member 12A
increases expression
EXP
2,3-pentanedione results in increased expression of TNFRSF12A mRNA
CTD
PMID:25710175
NCBI chr10:12,707,077...12,709,071
Ensembl chr10:12,689,890...12,709,045
G
Tnn
tenascin N
increases expression
EXP
2,3-pentanedione results in increased expression of TNN mRNA
CTD
PMID:25710175
NCBI chr13:72,319,160...72,386,362
Ensembl chr13:72,319,155...72,408,156
G
Ubr2
ubiquitin protein ligase E3 component n-recognin 2
increases expression
EXP
2,3-pentanedione results in increased expression of UBR2 mRNA
CTD
PMID:25710175
NCBI chr 9:13,982,427...14,062,315
Ensembl chr 9:13,982,329...14,062,139
G
Zfp318
zinc finger protein 318
increases expression
EXP
2,3-pentanedione results in increased expression of ZFP318 mRNA
CTD
PMID:25710175
NCBI chr 9:14,562,958...14,601,557
Ensembl chr 9:14,563,313...14,601,409
G
Zfp853
zinc finger protein 853
decreases expression
EXP
2,3-pentanedione results in decreased expression of ZFP853 mRNA
CTD
PMID:25710175
NCBI chr12:11,266,124...11,276,492
Ensembl chr12:11,269,414...11,275,731
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