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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:inorganic hydroxy compound
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Accession:CHEBI:52625 term browser browse the term
Synonyms:related_synonym: inorganic hydroxides


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ammonium hydroxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression EXP Ammonium Hydroxide results in increased expression of FOS protein CTD PMID:14750966 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression		 ISO Ammonium Hydroxide results in increased expression of and results in increased activity of HMOX1 protein
Ammonium Hydroxide results in increased expression of HMOX1 mRNA		 CTD PMID:27867098 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
calcium dihydroxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alpl alkaline phosphatase, biomineralization associated increases expression ISO Calcium Hydroxide results in increased expression of ALPL mRNA CTD PMID:22083529 NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446 		JBrowse link
G Col1a1 collagen type I alpha 1 chain increases expression ISO Calcium Hydroxide results in increased expression of COL1A1 mRNA CTD PMID:22083529 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624 		JBrowse link
G Esr1 estrogen receptor 1 increases expression ISO Calcium Hydroxide results in increased expression of ESR1 mRNA CTD PMID:22083529 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Polg DNA polymerase gamma, catalytic subunit affects expression ISO Calcium Hydroxide affects the expression of POLG mRNA CTD PMID:30615914 NCBI chr 1:133,382,764...133,399,578
Ensembl chr 1:133,382,766...133,398,567 		JBrowse link
G Polg2 DNA polymerase gamma 2, accessory subunit affects expression ISO Calcium Hydroxide affects the expression of POLG2 mRNA CTD PMID:30615914 NCBI chr10:91,712,586...91,723,008
Ensembl chr10:91,712,586...91,723,008 		JBrowse link
G Tfam transcription factor A, mitochondrial affects expression ISO Calcium Hydroxide affects the expression of TFAM mRNA CTD PMID:30615914 NCBI chr20:17,356,243...17,368,293
Ensembl chr20:17,356,197...17,368,292 		JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 increases expression ISO Calcium Hydroxide results in increased expression of TRPV1 mRNA CTD PMID:22083529 NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513 		JBrowse link
carbidopa term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO [sarpogrelate co-treated with Carbidopa] inhibits the reaction [Cisplatin results in increased expression of BAX protein]; Carbidopa inhibits the reaction [Cisplatin results in increased expression of BAX protein] CTD PMID:34560070 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO [sarpogrelate co-treated with Carbidopa] inhibits the reaction [Cisplatin results in decreased expression of BCL2 protein]
[sarpogrelate co-treated with Carbidopa] inhibits the reaction [Cisplatin results in decreased expression of BCL2 protein]; Carbidopa inhibits the reaction [Cisplatin results in decreased expression of BCL2 protein]		 CTD PMID:34560070 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Casp3 caspase 3 multiple interactions ISO [sarpogrelate co-treated with Carbidopa] inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]
[sarpogrelate co-treated with Carbidopa] inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]; Carbidopa inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]		 CTD PMID:34560070 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp9 caspase 9 multiple interactions ISO [sarpogrelate co-treated with Carbidopa] inhibits the reaction [Cisplatin results in increased cleavage of CASP9 protein]
[sarpogrelate co-treated with Carbidopa] inhibits the reaction [Cisplatin results in increased cleavage of CASP9 protein]; Carbidopa inhibits the reaction [Cisplatin results in increased cleavage of CASP9 protein]		 CTD PMID:34560070 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Comt catechol-O-methyltransferase increases methylation ISO
EXP		 COMT protein results in increased methylation of Carbidopa CTD PMID:11160877 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642 		JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO [sarpogrelate co-treated with Carbidopa] inhibits the reaction [Cisplatin results in increased expression of IL1B protein]
[sarpogrelate co-treated with Carbidopa] inhibits the reaction [Cisplatin results in increased secretion of IL1B protein]; Carbidopa inhibits the reaction [Cisplatin results in increased secretion of IL1B protein]		 CTD PMID:34560070 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Maoa monoamine oxidase A multiple interactions ISO [sarpogrelate co-treated with Carbidopa] inhibits the reaction [Cisplatin results in increased expression of MAOA protein]; Carbidopa inhibits the reaction [Cisplatin results in increased expression of MAOA protein] CTD PMID:34560070 NCBI chr  X:6,032,172...6,098,308
Ensembl chr  X:6,030,795...6,099,593 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO [sarpogrelate co-treated with Carbidopa] inhibits the reaction [Cisplatin results in increased phosphorylation of RELA protein]; Carbidopa inhibits the reaction [Cisplatin results in increased phosphorylation of RELA protein] CTD PMID:34560070 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO [sarpogrelate co-treated with Carbidopa] inhibits the reaction [Cisplatin results in increased phosphorylation of STAT3 protein]; Carbidopa inhibits the reaction [Cisplatin results in increased phosphorylation of STAT3 protein] CTD PMID:34560070 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO [sarpogrelate co-treated with Carbidopa] inhibits the reaction [Cisplatin results in increased expression of TNF protein]
[sarpogrelate co-treated with Carbidopa] inhibits the reaction [Cisplatin results in increased secretion of TNF protein]; Carbidopa inhibits the reaction [Cisplatin results in increased secretion of TNF protein]		 CTD PMID:34560070 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
ceftazidime pentahydrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc4 ATP binding cassette subfamily C member 4 increases transport ISO ABCC4 protein results in increased transport of Ceftazidime CTD PMID:17939016 NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283 		JBrowse link
G Dhfr dihydrofolate reductase decreases activity ISO Ceftazidime results in decreased activity of DHFR protein CTD PMID:25418905 NCBI chr 2:23,585,876...23,611,199
Ensembl chr 2:23,586,031...23,613,713 		JBrowse link
G Hsf1 heat shock transcription factor 1 decreases activity ISO Ceftazidime results in decreased activity of HSF1 protein CTD PMID:34170685 NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011 		JBrowse link
G Il10 interleukin 10 multiple interactions ISO Ceftazidime inhibits the reaction [Lipopolysaccharides results in increased secretion of IL10 protein] CTD PMID:16939481 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
cilazapril monohydrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme affects response to substance ISO ACE gene polymorphism affects the susceptibility to Cilazapril CTD PMID:15498266 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing increases expression ISO Cilazapril results in increased expression of ADIPOQ protein CTD PMID:19789415 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564 		JBrowse link
G Agtr1a angiotensin II receptor, type 1a multiple interactions EXP [Cilazapril co-treated with Losartan] promotes the reaction [Doxorubicin results in increased expression of AGTR1 mRNA]; Cilazapril promotes the reaction [Doxorubicin results in increased expression of AGTR1 mRNA] CTD PMID:15331931 NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946 		JBrowse link
G Agtr2 angiotensin II receptor, type 2 multiple interactions EXP [Losartan co-treated with Cilazapril] inhibits the reaction [Doxorubicin results in decreased expression of AGTR2 mRNA]; Cilazapril inhibits the reaction [Doxorubicin results in decreased expression of AGTR2 mRNA] CTD PMID:15331931 NCBI chr  X:112,119,673...112,124,060
Ensembl chr  X:112,120,228...112,124,057 		JBrowse link
G Fgf2 fibroblast growth factor 2 decreases expression EXP Cilazapril results in decreased expression of FGF2 mRNA; Cilazapril results in decreased expression of FGF2 protein CTD PMID:9640960 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221 		JBrowse link
G Nppa natriuretic peptide A multiple interactions
affects secretion		 ISO [Cilazapril co-treated with Verapamil] affects the secretion of NPPA protein
Cilazapril affects the secretion of NPPA protein		 CTD PMID:1457087 NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351 		JBrowse link
G Ren renin increases activity EXP Cilazapril results in increased activity of REN protein CTD PMID:2425185 NCBI chr13:44,796,260...44,807,491
Ensembl chr13:44,796,091...44,807,489 		JBrowse link
G Slc15a1 solute carrier family 15 member 1 multiple interactions ISO Cilazapril inhibits the reaction [SLC15A1 protein results in increased uptake of glycylsarcosine] CTD PMID:18713951 NCBI chr15:98,537,641...98,582,544
Ensembl chr15:98,537,641...98,582,545 		JBrowse link
G Slc15a2 solute carrier family 15 member 2 multiple interactions EXP Cilazapril inhibits the reaction [SLC15A2 protein results in increased uptake of glycylsarcosine] CTD PMID:18713951 NCBI chr11:64,014,182...64,043,228
Ensembl chr11:64,014,182...64,043,225 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP [Losartan co-treated with Cilazapril] inhibits the reaction [Doxorubicin results in increased expression of TGFB1 protein]; Cilazapril inhibits the reaction [Doxorubicin results in increased expression of TGFB1 protein] CTD PMID:15331931 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin decreases expression ISO Antimony Potassium Tartrate results in decreased expression of A2M mRNA CTD PMID:17547211 NCBI chr 4:154,897,770...154,947,787
Ensembl chr 4:154,897,877...154,947,786 		JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 affects response to substance
decreases response to substance
increases secretion
multiple interactions		 ISO ABCC1 protein affects the susceptibility to Antimony Potassium Tartrate
ABCC1 protein results in decreased susceptibility to Antimony Potassium Tartrate
ABCC1 protein results in increased secretion of Antimony Potassium Tartrate
[MYCN protein affects the expression of ABCC1 mRNA] which affects the susceptibility to Antimony Potassium Tartrate; Glutathione affects the reaction [ABCC1 protein results in increased secretion of Antimony Potassium Tartrate]; verlukast inhibits the reaction [ABCC1 protein results in decreased susceptibility to Antimony Potassium Tartrate]; verlukast inhibits the reaction [ABCC1 protein results in increased secretion of Antimony Potassium Tartrate]		 CTD PMID:10025956 PMID:10348353 PMID:11278867 PMID:12018890 PMID:12731862 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114 		JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 increases expression
multiple interactions		 EXP
ISO		 Antimony Potassium Tartrate results in increased expression of ABCC2 mRNA; Antimony Potassium Tartrate results in increased expression of ABCC2 protein
[Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of ABCC2 mRNA		 CTD PMID:11408547 PMID:32076005 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238 		JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of ABCC3 mRNA CTD PMID:32076005 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595 		JBrowse link
G Acp2 acid phosphatase 2, lysosomal decreases expression ISO Antimony Potassium Tartrate results in decreased expression of ACP2 mRNA CTD PMID:17547211 NCBI chr 3:77,175,022...77,185,180
Ensembl chr 3:77,175,895...77,185,680 		JBrowse link
G Acsl1 acyl-CoA synthetase long-chain family member 1 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of ACSL1 mRNA CTD PMID:17547211 NCBI chr16:45,755,246...45,821,541
Ensembl chr16:45,755,254...45,821,541 		JBrowse link
G Adm adrenomedullin increases expression ISO Antimony Potassium Tartrate results in increased expression of ADM mRNA CTD PMID:17547211 NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654 		JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B1 decreases expression
increases expression		 ISO Antimony Potassium Tartrate results in decreased expression of AKR1B1 mRNA
Antimony Potassium Tartrate results in increased expression of AKR1B1 mRNA		 CTD PMID:17547211 PMID:28713220 NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157 		JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 increases expression
multiple interactions		 ISO Antimony Potassium Tartrate results in increased expression of AKR1B10 mRNA
[Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of AKR1B10 mRNA		 CTD PMID:28713220 PMID:32076005 NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852 		JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 increases expression ISO Antimony Potassium Tartrate results in increased expression of AKR1C2 protein CTD PMID:28713220 NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764 		JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 increases expression
multiple interactions		 ISO Antimony Potassium Tartrate results in increased expression of AKR1C3 mRNA; Antimony Potassium Tartrate results in increased expression of AKR1C3 protein
[Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of AKR1C3 mRNA		 CTD PMID:28713220 PMID:32076005 NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873 		JBrowse link
G Aldh3a2 aldehyde dehydrogenase 3 family, member A2 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of ALDH3A2 mRNA CTD PMID:32076005 NCBI chr10:45,928,313...45,949,366
Ensembl chr10:45,908,524...45,949,281 		JBrowse link
G Aldh3b2 aldehyde dehydrogenase 3 family, member B2 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of ALDH3B2 mRNA CTD PMID:32076005 NCBI chr 1:201,250,260...201,264,699
Ensembl chr 1:201,253,157...201,264,705 		JBrowse link
G Aldh6a1 aldehyde dehydrogenase 6 family, member A1 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of ALDH6A1 mRNA CTD PMID:17547211 NCBI chr 6:104,077,975...104,098,636
Ensembl chr 6:104,077,979...104,098,656 		JBrowse link
G Aldoa aldolase, fructose-bisphosphate A increases expression ISO Antimony Potassium Tartrate results in increased expression of ALDOA mRNA CTD PMID:28713220 NCBI chr 1:181,402,275...181,407,476
Ensembl chr 1:181,402,275...181,406,182 		JBrowse link
G Aldoc aldolase, fructose-bisphosphate C increases expression ISO Antimony Potassium Tartrate results in increased expression of ALDOC mRNA CTD PMID:28713220 NCBI chr10:63,217,477...63,221,066
Ensembl chr10:63,217,451...63,221,066 		JBrowse link
G Ar androgen receptor increases phosphorylation ISO Antimony Potassium Tartrate results in increased phosphorylation of AR protein CTD PMID:29462692 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Atp2b1 ATPase plasma membrane Ca2+ transporting 1 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of ATP2B1 mRNA CTD PMID:17547211 NCBI chr 7:33,735,595...33,845,226
Ensembl chr 7:33,735,871...33,843,295 		JBrowse link
G Azgp1 alpha-2-glycoprotein 1, zinc-binding decreases expression ISO Antimony Potassium Tartrate results in decreased expression of AZGP1 mRNA CTD PMID:17547211 NCBI chr12:16,930,990...16,939,333
Ensembl chr12:16,931,024...16,939,091 		JBrowse link
G Barx2 BARX homeobox 2 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of BARX2 mRNA CTD PMID:32076005 NCBI chr 8:30,251,132...30,319,105
Ensembl chr 8:30,251,132...30,319,013 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of Antimony] which results in increased expression of BAX protein CTD PMID:32920012 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions EXP
ISO		 666-15 compound promotes the reaction [[Antimony Potassium Tartrate results in increased abundance of Antimony] which results in decreased expression of BCL2 protein]; [Antimony Potassium Tartrate results in increased abundance of Antimony] which results in decreased expression of BCL2 protein CTD PMID:32920012 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bmp6 bone morphogenetic protein 6 multiple interactions ISO Antimony Potassium Tartrate inhibits the reaction [BMP6 protein results in increased expression of DUSP12 mRNA]; Antimony Potassium Tartrate inhibits the reaction [BMP6 protein results in increased expression of DUSP2 mRNA] CTD PMID:28713220 NCBI chr17:26,318,121...26,469,034
Ensembl chr17:26,318,569...26,470,365 		JBrowse link
G Btf3 basic transcription factor 3 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of BTF3 mRNA CTD PMID:32076005 NCBI chr 2:29,659,764...29,666,898
Ensembl chr 2:29,659,231...29,666,879 		JBrowse link
G Btg2 BTG anti-proliferation factor 2 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of BTG2 mRNA CTD PMID:32076005 NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628 		JBrowse link
G Calml5 calmodulin-like 5 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of CALML5 mRNA CTD PMID:28713220 NCBI chr17:66,394,433...66,395,390 JBrowse link
G Calr calreticulin multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of CALR mRNA CTD PMID:32076005 NCBI chr19:23,308,525...23,313,420
Ensembl chr19:23,308,351...23,313,414 		JBrowse link
G Casp3 caspase 3 multiple interactions EXP
ISO		 [Antimony Potassium Tartrate results in increased abundance of Antimony] which results in increased cleavage of CASP3 protein CTD PMID:32920012 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Ccnb2 cyclin B2 increases expression ISO Antimony Potassium Tartrate results in increased expression of CCNB2 mRNA CTD PMID:17547211 NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874 		JBrowse link
G Ccnd1 cyclin D1 multiple interactions EXP 666-15 compound inhibits the reaction [[Antimony Potassium Tartrate results in increased abundance of Antimony] which results in increased expression of CCND1 protein]; [Antimony Potassium Tartrate results in increased abundance of Antimony] which results in increased expression of CCND1 protein; SB 203580 inhibits the reaction [[Antimony Potassium Tartrate results in increased abundance of Antimony] which results in increased expression of CCND1 protein]; U 0126 inhibits the reaction [[Antimony Potassium Tartrate results in increased abundance of Antimony] which results in increased expression of CCND1 protein] CTD PMID:34571074 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO Antimony Potassium Tartrate results in increased expression of CDKN1A mRNA CTD PMID:17547211 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cdkn2b cyclin-dependent kinase inhibitor 2B multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of CDKN2B mRNA CTD PMID:32076005 NCBI chr 5:104,009,839...104,019,082
Ensembl chr 5:104,010,680...104,019,050 		JBrowse link
G Cdkn3 cyclin-dependent kinase inhibitor 3 increases expression ISO Antimony Potassium Tartrate results in increased expression of CDKN3 mRNA CTD PMID:17547211 NCBI chr15:20,022,522...20,033,948
Ensembl chr15:20,022,664...20,033,945 		JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of CEBPA mRNA CTD PMID:32076005 NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412 		JBrowse link
G Cfb complement factor B decreases expression ISO Antimony Potassium Tartrate results in decreased expression of CFB mRNA CTD PMID:17547211 NCBI chr20:3,970,643...3,976,510
Ensembl chr20:3,951,474...3,976,505 		JBrowse link
G Cks2 CDC28 protein kinase regulatory subunit 2 increases expression ISO Antimony Potassium Tartrate results in increased expression of CKS2 mRNA CTD PMID:17547211 NCBI chr17:13,570,611...13,575,770 JBrowse link
G Clgn calmegin decreases expression ISO Antimony Potassium Tartrate results in decreased expression of CLGN mRNA CTD PMID:17547211 NCBI chr19:24,695,140...24,728,542
Ensembl chr19:24,696,875...24,728,758 		JBrowse link
G Clptm1 CLPTM1 regulator of GABA type A receptor forward trafficking decreases expression ISO Antimony Potassium Tartrate results in decreased expression of CLPTM1 mRNA CTD PMID:17547211 NCBI chr 1:79,289,478...79,321,079
Ensembl chr 1:79,289,477...79,321,092 		JBrowse link
G Cnbp CCHC-type zinc finger, nucleic acid binding protein multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of CNBP mRNA CTD PMID:32076005 NCBI chr 4:120,302,768...120,311,694
Ensembl chr 4:120,302,771...120,311,637 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions ISO
EXP		 [Antimony Potassium Tartrate results in increased abundance of Antimony] which results in increased phosphorylation of CREB1 protein
[Antimony Potassium Tartrate results in increased abundance of Antimony] which results in increased phosphorylation of CREB1 protein; pyrazolanthrone inhibits the reaction [[Antimony Potassium Tartrate results in increased abundance of Antimony] which results in increased phosphorylation of CREB1 protein]; SB 203580 inhibits the reaction [[Antimony Potassium Tartrate results in increased abundance of Antimony] which results in increased phosphorylation of CREB1 protein]; U 0126 inhibits the reaction [[Antimony Potassium Tartrate results in increased abundance of Antimony] which results in increased phosphorylation of CREB1 protein]		 CTD PMID:32920012 PMID:34571074 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of CYP1B1 mRNA CTD PMID:32076005 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917 		JBrowse link
G Dazap1 DAZ associated protein 1 increases expression ISO Antimony Potassium Tartrate results in increased expression of DAZAP1 mRNA CTD PMID:17547211 NCBI chr 7:9,423,673...9,448,116
Ensembl chr 7:9,424,178...9,538,818 		JBrowse link
G Dcp1a decapping mRNA 1A increases expression ISO Antimony Potassium Tartrate results in increased expression of DCP1A mRNA CTD PMID:17547211 NCBI chr16:5,656,788...5,702,151
Ensembl chr16:5,656,773...5,702,140 		JBrowse link
G Dhrs9 dehydrogenase/reductase 9 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of DHRS9 mRNA CTD PMID:32076005 NCBI chr 3:54,147,834...54,170,052
Ensembl chr 3:54,147,803...54,220,241 		JBrowse link
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of DNAJB1 mRNA CTD PMID:32076005 NCBI chr19:24,522,717...24,526,458
Ensembl chr19:24,522,717...24,526,458 		JBrowse link
G Dnajb4 DnaJ heat shock protein family (Hsp40) member B4 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of DNAJB4 mRNA CTD PMID:32076005 NCBI chr 2:241,129,346...241,159,272
Ensembl chr 2:241,130,340...241,159,089 		JBrowse link
G Dsc1 desmocollin 1 decreases expression
multiple interactions		 ISO Antimony Potassium Tartrate results in decreased expression of DSC1 mRNA
[Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of DSC1 mRNA; U 0126 inhibits the reaction [[Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of DSC1 mRNA]		 CTD PMID:28713220 PMID:32076005 NCBI chr18:11,499,936...11,556,801
Ensembl chr18:11,502,003...11,528,494 		JBrowse link
G Dsg1 desmoglein 1 multiple interactions ISO 2-tert-butyl-9-fluoro-3,6-dihydro-7H-benz(h)imidazo(4,5-f)isoquinoline-7-one promotes the reaction [[Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of DSG1 mRNA]; [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of DSG1 mRNA; Hydrocortisone inhibits the reaction [[Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of DSG1 mRNA]; U 0126 inhibits the reaction [[Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of DSG1 mRNA] CTD PMID:32076005 NCBI chr18:11,674,687...11,705,383
Ensembl chr18:11,674,402...11,703,443 		JBrowse link
G Dst dystonin decreases expression ISO Antimony Potassium Tartrate results in decreased expression of DST protein CTD PMID:28713220 NCBI chr 9:36,135,657...36,529,617
Ensembl chr 9:36,135,284...36,529,615 		JBrowse link
G Duox1 dual oxidase 1 multiple interactions
decreases expression		 ISO Antimony Potassium Tartrate inhibits the reaction [IL4 protein results in increased expression of DUOX1 mRNA]
Antimony Potassium Tartrate results in decreased expression of DUOX1 mRNA		 CTD PMID:29031483 NCBI chr 3:109,260,526...109,295,588
Ensembl chr 3:109,262,397...109,295,563 		JBrowse link
G Duoxa1 dual oxidase maturation factor 1 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of DUOXA1 mRNA CTD PMID:29031483 NCBI chr 3:109,249,815...109,260,511
Ensembl chr 3:109,249,923...109,260,499 		JBrowse link
G Dusp1 dual specificity phosphatase 1 increases expression ISO Antimony Potassium Tartrate results in increased expression of DUSP1 mRNA CTD PMID:17547211 NCBI chr10:16,680,489...16,683,276 JBrowse link
G Dusp12 dual specificity phosphatase 12 multiple interactions ISO Antimony Potassium Tartrate inhibits the reaction [BMP6 protein results in increased expression of DUSP12 mRNA] CTD PMID:28713220 NCBI chr13:83,122,192...83,131,800
Ensembl chr13:83,122,193...83,131,285 		JBrowse link
G Dusp2 dual specificity phosphatase 2 multiple interactions ISO Antimony Potassium Tartrate inhibits the reaction [BMP6 protein results in increased expression of DUSP2 mRNA] CTD PMID:28713220 NCBI chr 3:114,556,325...114,558,510
Ensembl chr 3:114,556,325...114,558,499 		JBrowse link
G Egr3 early growth response 3 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of EGR3 mRNA CTD PMID:32076005 NCBI chr15:45,150,335...45,156,052
Ensembl chr15:45,150,567...45,154,627 		JBrowse link
G Ehf ets homologous factor multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of EHF mRNA CTD PMID:32076005 NCBI chr 3:89,639,845...89,680,061
Ensembl chr 3:89,641,833...89,679,997 		JBrowse link
G Elf3 E74 like ETS transcription factor 3 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of ELF3 mRNA CTD PMID:32076005 NCBI chr13:46,690,460...46,695,394
Ensembl chr13:46,690,466...46,695,481 		JBrowse link
G Epha1 Eph receptor A1 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of EPHA1 protein CTD PMID:32076005 NCBI chr 4:71,246,409...71,260,920
Ensembl chr 4:71,246,409...71,260,846 		JBrowse link
G Epha2 Eph receptor A2 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of EPHA2 protein CTD PMID:32076005 NCBI chr 5:153,605,644...153,634,115
Ensembl chr 5:153,605,644...153,634,117 		JBrowse link
G Ephx1 epoxide hydrolase 1 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of EPHX1 mRNA CTD PMID:32076005 NCBI chr13:92,714,315...92,744,124
Ensembl chr13:92,714,315...92,790,235 		JBrowse link
G F5 coagulation factor V decreases expression ISO Antimony Potassium Tartrate results in decreased expression of F5 mRNA CTD PMID:17547211 NCBI chr13:76,513,463...76,583,106
Ensembl chr13:76,513,255...76,582,317 		JBrowse link
G Fabp5 fatty acid binding protein 5 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of FABP5 mRNA CTD PMID:28713220 NCBI chr 2:91,765,056...91,768,716
Ensembl chr 2:91,765,056...91,853,773 		JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of FDFT1 mRNA CTD PMID:17547211 NCBI chr15:37,412,143...37,440,198
Ensembl chr15:37,412,146...37,440,287 		JBrowse link
G Fdps farnesyl diphosphate synthase decreases expression ISO Antimony Potassium Tartrate results in decreased expression of FDPS mRNA CTD PMID:17547211 NCBI chr 2:174,497,402...174,507,031
Ensembl chr 2:174,486,665...174,507,776 		JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of FGFR3 mRNA CTD PMID:32076005 NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341 		JBrowse link
G Flg filaggrin decreases expression
multiple interactions		 ISO Antimony Potassium Tartrate results in decreased expression of FLG mRNA
2-tert-butyl-9-fluoro-3,6-dihydro-7H-benz(h)imidazo(4,5-f)isoquinoline-7-one promotes the reaction [[Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of FLG mRNA]; [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of FLG mRNA; Hydrocortisone inhibits the reaction [[Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of FLG mRNA]; U 0126 inhibits the reaction [[Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of FLG mRNA]		 CTD PMID:28713220 PMID:32076005 NCBI chr 2:178,888,688...178,912,731 JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of FOS mRNA CTD PMID:32076005 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit increases expression ISO Antimony Potassium Tartrate results in increased expression of FOSL1 mRNA CTD PMID:17547211 NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930 		JBrowse link
G Foxq1 forkhead box Q1 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of FOXQ1 mRNA CTD PMID:32076005 NCBI chr17:32,912,744...32,915,377
Ensembl chr17:32,912,744...32,915,377
Ensembl chr17:32,912,744...32,915,377 		JBrowse link
G Fth1 ferritin heavy chain 1 increases expression
multiple interactions		 ISO Antimony Potassium Tartrate results in increased expression of FTH1 mRNA; Antimony Potassium Tartrate results in increased expression of FTH1 protein
[Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of FTH1 mRNA		 CTD PMID:28713220 PMID:32076005 NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424 		JBrowse link
G Ftl1 ferritin light chain 1 increases expression
multiple interactions		 ISO Antimony Potassium Tartrate results in increased expression of FTL mRNA
[Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of FTL mRNA		 CTD PMID:28713220 PMID:32076005 NCBI chr 1:95,936,390...95,938,234
Ensembl chr 1:95,936,387...95,939,725 		JBrowse link
G G6pd glucose-6-phosphate dehydrogenase increases expression ISO Antimony Potassium Tartrate results in increased expression of G6PD mRNA; Antimony Potassium Tartrate results in increased expression of G6PD protein CTD PMID:28713220 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801 		JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase increases expression ISO Antimony Potassium Tartrate results in increased expression of GAPDH mRNA CTD PMID:28713220 NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression
multiple interactions		 ISO Antimony Potassium Tartrate results in increased expression of GCLC mRNA; Antimony Potassium Tartrate results in increased expression of GCLC protein
[Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of GCLC mRNA		 CTD PMID:28713220 PMID:32076005 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544 		JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression
multiple interactions		 ISO Antimony Potassium Tartrate results in increased expression of GCLM mRNA
[Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of GCLM mRNA		 CTD PMID:28713220 PMID:32076005 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535 		JBrowse link
G Gcnt3 glucosaminyl (N-acetyl) transferase 3, mucin type increases expression ISO Antimony Potassium Tartrate results in increased expression of GCNT3 mRNA CTD PMID:17547211 NCBI chr 8:70,689,173...70,696,476
Ensembl chr 8:70,686,844...70,699,562 		JBrowse link
G Gfap glial fibrillary acidic protein multiple interactions EXP
ISO		 666-15 compound inhibits the reaction [[Antimony Potassium Tartrate results in increased abundance of Antimony] which results in increased expression of GFAP protein]; [Antimony Potassium Tartrate results in increased abundance of Antimony] which results in increased expression of GFAP mRNA; [Antimony Potassium Tartrate results in increased abundance of Antimony] which results in increased expression of GFAP protein; SB 203580 inhibits the reaction [[Antimony Potassium Tartrate results in increased abundance of Antimony] which results in increased expression of GFAP mRNA]; SB 203580 inhibits the reaction [[Antimony Potassium Tartrate results in increased abundance of Antimony] which results in increased expression of GFAP protein]; U 0126 inhibits the reaction [[Antimony Potassium Tartrate results in increased abundance of Antimony] which results in increased expression of GFAP mRNA] CTD PMID:34571074 NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589 		JBrowse link
G Ggt1 gamma-glutamyltransferase 1 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of GGT1 mRNA CTD PMID:32076005 NCBI chr20:13,074,695...13,104,095
Ensembl chr20:13,074,700...13,108,442 		JBrowse link
G Ghitm growth hormone inducible transmembrane protein decreases expression ISO Antimony Potassium Tartrate results in decreased expression of GHITM mRNA CTD PMID:17547211 NCBI chr16:12,885,551...12,897,887
Ensembl chr16:12,885,553...12,897,879 		JBrowse link
G Gla galactosidase, alpha increases expression ISO Antimony Potassium Tartrate results in increased expression of GLA mRNA CTD PMID:17547211 NCBI chr  X:97,769,227...97,780,646
Ensembl chr  X:97,768,996...97,780,664 		JBrowse link
G Glrx glutaredoxin multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of GLRX mRNA CTD PMID:32076005 NCBI chr 2:5,341,873...5,351,686
Ensembl chr 2:5,341,885...5,351,680 		JBrowse link
G Gpx2 glutathione peroxidase 2 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of GPX2 mRNA CTD PMID:32076005 NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877 		JBrowse link
G Grhl1 grainyhead-like transcription factor 1 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of GRHL1 mRNA CTD PMID:32076005 NCBI chr 6:41,207,325...41,257,516
Ensembl chr 6:41,207,348...41,254,301 		JBrowse link
G Gsto1 glutathione S-transferase omega 1 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of GSTO1 mRNA CTD PMID:32076005 NCBI chr 1:246,721,089...246,731,228
Ensembl chr 1:246,721,221...246,731,468 		JBrowse link
G Gtpbp6 GTP binding protein 6 (putative) increases expression ISO Antimony Potassium Tartrate results in increased expression of GTPBP6 mRNA CTD PMID:17547211 NCBI chr12:46,574,913...46,578,873
Ensembl chr12:46,574,435...46,578,873 		JBrowse link
G H4c3 H4 clustered histone 3 increases expression ISO Antimony Potassium Tartrate results in increased expression of H4C3 mRNA CTD PMID:17547211
G Hltf helicase-like transcription factor multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of HLTF mRNA CTD PMID:32076005 NCBI chr 2:102,549,724...102,609,492
Ensembl chr 2:102,549,724...102,609,327 		JBrowse link
G Hmga1 high mobility group AT-hook 1 increases expression ISO Antimony Potassium Tartrate results in increased expression of HMGA1 mRNA CTD PMID:17547211 NCBI chr20:5,611,088...5,618,755
Ensembl chr20:5,611,694...5,618,752 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions		 ISO Antimony Potassium Tartrate results in increased expression of HMOX1 mRNA; Antimony Potassium Tartrate results in increased expression of HMOX1 protein
[Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of HMOX1 mRNA		 CTD PMID:17547211 PMID:28713220 PMID:32076005 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hopx HOP homeobox multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of HOPX mRNA CTD PMID:32076005 NCBI chr14:31,055,912...31,082,909
Ensembl chr14:31,075,148...31,082,909 		JBrowse link
G Hsd17b2 hydroxysteroid (17-beta) dehydrogenase 2 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of HSD17B2 mRNA CTD PMID:17547211 NCBI chr19:45,753,576...45,825,203
Ensembl chr19:45,753,574...45,825,202 		JBrowse link
G Hsd17b7 hydroxysteroid (17-beta) dehydrogenase 7 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of HSD17B7 mRNA CTD PMID:17547211 NCBI chr13:82,170,079...82,190,018
Ensembl chr13:82,173,179...82,190,017 		JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of HSPA1A mRNA CTD PMID:32076005
G Hspa8 heat shock protein family A (Hsp70) member 8 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of HSPA8 mRNA CTD PMID:32076005 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259 		JBrowse link
G Hspb8 heat shock protein family B (small) member 8 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of HSPB8 mRNA CTD PMID:32076005 NCBI chr12:40,176,405...40,205,002
Ensembl chr12:40,176,532...40,191,185 		JBrowse link
G Htatip2 HIV-1 Tat interactive protein 2 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of HTATIP2 mRNA CTD PMID:32076005 NCBI chr 1:99,473,411...99,488,632
Ensembl chr 1:99,469,245...99,488,629 		JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of ID1 mRNA CTD PMID:32076005 NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419 		JBrowse link
G Ier2 immediate early response 2 increases expression ISO Antimony Potassium Tartrate results in increased expression of IER2 mRNA CTD PMID:17547211 NCBI chr19:23,494,551...23,496,075
Ensembl chr19:23,494,184...23,499,211 		JBrowse link
G Ifrd1 interferon-related developmental regulator 1 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of IFRD1 mRNA CTD PMID:17547211 NCBI chr 6:57,269,395...57,317,833
Ensembl chr 6:57,269,384...57,288,990 		JBrowse link
G Ikzf2 IKAROS family zinc finger 2 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of IKZF2 mRNA CTD PMID:32076005 NCBI chr 9:71,042,440...71,191,296
Ensembl chr 9:71,042,440...71,190,867 		JBrowse link
G Il1rn interleukin 1 receptor antagonist multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of IL1RN mRNA CTD PMID:32076005 NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445 		JBrowse link
G Il4 interleukin 4 multiple interactions ISO Antimony Potassium Tartrate inhibits the reaction [IL4 protein results in increased expression of DUOX1 mRNA] CTD PMID:29031483 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Ing3 inhibitor of growth family, member 3 increases expression ISO Antimony Potassium Tartrate results in increased expression of ING3 mRNA CTD PMID:17547211 NCBI chr 4:50,477,954...50,505,168
Ensembl chr 4:50,477,962...50,503,715 		JBrowse link
G Itgb3bp integrin subunit beta 3 binding protein increases expression ISO Antimony Potassium Tartrate results in increased expression of ITGB3BP mRNA CTD PMID:17547211 NCBI chr 5:114,460,217...114,525,538
Ensembl chr 5:114,460,221...114,525,704 		JBrowse link
G Itih3 inter-alpha trypsin inhibitor, heavy chain 3 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of ITIH3 mRNA CTD PMID:17547211 NCBI chr16:6,101,922...6,117,154
Ensembl chr16:6,101,930...6,116,924 		JBrowse link
G Ivl involucrin decreases expression
multiple interactions		 ISO Antimony Potassium Tartrate results in decreased expression of IVL mRNA; Antimony Potassium Tartrate results in decreased expression of IVL protein
[Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of IVL mRNA		 CTD PMID:28713220 PMID:32076005 NCBI chr 2:178,146,694...178,160,807
Ensembl chr 2:178,147,061...178,149,100 		JBrowse link
G Klf5 Kruppel-like factor 5 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of KLF5 mRNA CTD PMID:32076005 NCBI chr15:76,060,320...76,079,445
Ensembl chr15:76,064,258...76,079,445 		JBrowse link
G Klf6 Kruppel-like factor 6 increases expression ISO Antimony Potassium Tartrate results in increased expression of KLF6 mRNA CTD PMID:17547211 NCBI chr17:64,539,456...64,548,451
Ensembl chr17:64,531,463...64,588,570 		JBrowse link
G Krt1 keratin 1 multiple interactions ISO 2-tert-butyl-9-fluoro-3,6-dihydro-7H-benz(h)imidazo(4,5-f)isoquinoline-7-one promotes the reaction [[Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of KRT1 mRNA]; [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of KRT1 mRNA; Hydrocortisone inhibits the reaction [[Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of KRT1 mRNA]; U 0126 inhibits the reaction [[Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of KRT1 mRNA] CTD PMID:32076005 NCBI chr 7:132,976,618...132,981,844
Ensembl chr 7:132,976,620...132,981,844 		JBrowse link
G Krt10 keratin 10 decreases expression
multiple interactions		 ISO Antimony Potassium Tartrate results in decreased expression of KRT10 mRNA; Antimony Potassium Tartrate results in decreased expression of KRT10 protein
2-tert-butyl-9-fluoro-3,6-dihydro-7H-benz(h)imidazo(4,5-f)isoquinoline-7-one promotes the reaction [[Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of KRT10 mRNA]; [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of KRT10 mRNA; Hydrocortisone inhibits the reaction [[Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of KRT10 mRNA]; U 0126 inhibits the reaction [[Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of KRT10 mRNA]		 CTD PMID:28713220 PMID:32076005 NCBI chr10:84,338,695...84,343,279
Ensembl chr10:84,338,706...84,343,701 		JBrowse link
G Krtdap keratinocyte differentiation associated protein decreases expression ISO Antimony Potassium Tartrate results in decreased expression of KRTDAP mRNA CTD PMID:28713220 NCBI chr 1:86,038,296...86,041,594
Ensembl chr 1:86,038,437...86,041,455 		JBrowse link
G Lipa lipase A, lysosomal acid type decreases expression ISO Antimony Potassium Tartrate results in decreased expression of LIPA mRNA CTD PMID:17547211 NCBI chr 1:232,024,351...232,167,329
Ensembl chr 1:232,024,356...232,057,633 		JBrowse link
G LOC102556347 carbonyl reductase [NADPH] 1-like multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of CBR1 mRNA CTD PMID:32076005 NCBI chr11:32,892,640...32,895,277
Ensembl chr11:32,857,991...32,895,275 		JBrowse link
G Loricrin loricrin cornified envelope precursor protein multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of LORICRIN mRNA CTD PMID:32076005 NCBI chr 2:177,558,062...177,559,980
Ensembl chr 2:177,558,252...177,559,807 		JBrowse link
G Lrig1 leucine-rich repeats and immunoglobulin-like domains 1 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of LRIG1 mRNA CTD PMID:28713220 NCBI chr 4:127,130,899...127,230,956
Ensembl chr 4:127,130,898...127,231,513 		JBrowse link
G Lss lanosterol synthase decreases expression ISO Antimony Potassium Tartrate results in decreased expression of LSS mRNA CTD PMID:17547211 NCBI chr20:12,091,138...12,118,858
Ensembl chr20:12,092,774...12,118,762 		JBrowse link
G Maff MAF bZIP transcription factor F increases expression ISO Antimony Potassium Tartrate results in increased expression of MAFF mRNA CTD PMID:17547211 NCBI chr 7:110,912,499...110,923,851
Ensembl chr 7:110,912,499...110,923,851 		JBrowse link
G Man1a2 mannosidase, alpha, class 1A, member 2 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of MAN1A2 mRNA CTD PMID:17547211 NCBI chr 2:187,947,484...188,096,332
Ensembl chr 2:187,951,617...188,096,332 		JBrowse link
G Maoa monoamine oxidase A multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of MAOA mRNA CTD PMID:32076005 NCBI chr  X:6,032,172...6,098,308
Ensembl chr  X:6,030,795...6,099,593 		JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of MAP2K1 mRNA CTD PMID:32076005 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions EXP
ISO		 [Antimony Potassium Tartrate results in increased abundance of Antimony] which results in increased phosphorylation of MAPK1 protein
[Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased phosphorylation of MAPK1 protein		 CTD PMID:32076005 PMID:32920012 PMID:34571074 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions EXP
ISO		 [Antimony Potassium Tartrate results in increased abundance of Antimony] which results in increased phosphorylation of MAPK3 protein
[Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased phosphorylation of MAPK3 protein		 CTD PMID:32076005 PMID:32920012 PMID:34571074 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mcm2 minichromosome maintenance complex component 2 increases expression ISO Antimony Potassium Tartrate results in increased expression of MCM2 mRNA CTD PMID:17547211 NCBI chr 4:121,346,434...121,360,962
Ensembl chr 4:121,346,434...121,360,847 		JBrowse link
G Me1 malic enzyme 1 increases expression ISO Antimony Potassium Tartrate results in increased expression of ME1 mRNA CTD PMID:28713220 NCBI chr 8:87,549,043...87,660,251
Ensembl chr 8:87,549,043...87,660,304 		JBrowse link
G Mgat2 alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase decreases expression ISO Antimony Potassium Tartrate results in decreased expression of MGAT2 mRNA CTD PMID:17547211 NCBI chr 6:87,656,360...87,658,849
Ensembl chr 6:87,656,349...87,658,177 		JBrowse link
G Mgst1 microsomal glutathione S-transferase 1 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of MGST1 mRNA CTD PMID:32076005 NCBI chr 4:171,029,666...171,044,893
Ensembl chr 4:171,029,630...171,044,892 		JBrowse link
G Mt2A metallothionein 2A increases expression ISO Antimony Potassium Tartrate results in increased expression of MT2A mRNA CTD PMID:28713220 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784 		JBrowse link
G Mycn MYCN proto-oncogene, bHLH transcription factor multiple interactions
decreases response to substance		 ISO [MYCN protein affects the expression of ABCC1 mRNA] which affects the susceptibility to Antimony Potassium Tartrate
MYCN protein results in decreased susceptibility to Antimony Potassium Tartrate		 CTD PMID:10348353 NCBI chr 6:35,717,764...35,723,590
Ensembl chr 6:35,717,764...35,723,590 		JBrowse link
G Ndrg2 NDRG family member 2 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of NDRG2 mRNA CTD PMID:17547211 NCBI chr15:24,600,981...24,609,621
Ensembl chr15:24,600,982...24,609,626 		JBrowse link
G Nfkb2 nuclear factor kappa B subunit 2 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of NFKB2 mRNA CTD PMID:32076005 NCBI chr 1:245,164,586...245,173,225
Ensembl chr 1:245,165,950...245,173,213 		JBrowse link
G Nfkbia NFKB inhibitor alpha decreases expression ISO Antimony Potassium Tartrate results in decreased expression of NFKBIA mRNA CTD PMID:17547211 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Nkx3-1 NK3 homeobox 1 increases expression
multiple interactions		 ISO Antimony Potassium Tartrate results in increased expression of NKX3-1 mRNA; Antimony Potassium Tartrate results in increased expression of NKX3-1 protein
bicalutamide inhibits the reaction [Antimony Potassium Tartrate results in increased expression of NKX3-1 mRNA]		 CTD PMID:29462692 NCBI chr15:44,473,851...44,476,443
Ensembl chr15:44,473,851...44,476,441 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions EXP
ISO		 666-15 compound inhibits the reaction [[Antimony Potassium Tartrate results in increased abundance of Antimony] which results in increased expression of NOS2 protein]; [Antimony Potassium Tartrate results in increased abundance of Antimony] which results in increased expression of NOS2 mRNA; [Antimony Potassium Tartrate results in increased abundance of Antimony] which results in increased expression of NOS2 protein; SB 203580 inhibits the reaction [[Antimony Potassium Tartrate results in increased abundance of Antimony] which results in increased expression of NOS2 mRNA]; SB 203580 inhibits the reaction [[Antimony Potassium Tartrate results in increased abundance of Antimony] which results in increased expression of NOS2 protein] CTD PMID:34571074 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression
multiple interactions		 ISO Antimony Potassium Tartrate results in increased expression of NQO1 mRNA; Antimony Potassium Tartrate results in increased expression of NQO1 protein
[Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of NQO1 mRNA		 CTD PMID:28713220 PMID:32076005 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Nqo2 N-ribosyldihydronicotinamide:quinone reductase 2 increases expression ISO Antimony Potassium Tartrate results in increased expression of NQO2 mRNA CTD PMID:28713220 NCBI chr17:30,909,482...30,938,725
Ensembl chr17:30,909,187...30,938,320 		JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of NR0B2 mRNA CTD PMID:17547211 NCBI chr 5:145,779,294...145,782,609
Ensembl chr 5:145,779,294...145,782,609 		JBrowse link
G Os9 OS9, endoplasmic reticulum lectin decreases expression ISO Antimony Potassium Tartrate results in decreased expression of OS9 mRNA CTD PMID:17547211 NCBI chr 7:62,915,498...62,957,591
Ensembl chr 7:62,915,515...62,943,745 		JBrowse link
G Osm oncostatin M multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] inhibits the reaction [OSM protein results in increased phosphorylation of STAT1 protein] CTD PMID:32076005 NCBI chr14:79,103,638...79,108,500
Ensembl chr14:79,104,344...79,108,313 		JBrowse link
G Pbx1 PBX homeobox 1 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of PBX1 mRNA CTD PMID:32076005 NCBI chr13:80,278,766...80,588,563
Ensembl chr13:80,278,770...80,588,594 		JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions EXP [Antimony Potassium Tartrate results in increased abundance of Antimony] which results in increased expression of PCNA protein CTD PMID:34571074 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995 		JBrowse link
G Pdia4 protein disulfide isomerase family A, member 4 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of PDIA4 mRNA CTD PMID:17547211 NCBI chr 4:76,803,198...76,822,245
Ensembl chr 4:76,803,198...76,822,107 		JBrowse link
G Pgc progastricsin decreases expression ISO Antimony Potassium Tartrate results in decreased expression of PGC mRNA CTD PMID:17547211 NCBI chr 9:13,257,462...13,265,682
Ensembl chr 9:13,257,462...13,265,682 		JBrowse link
G Pgd phosphogluconate dehydrogenase increases expression ISO Antimony Potassium Tartrate results in increased expression of PGD protein CTD PMID:28713220 NCBI chr 5:159,582,746...159,598,945
Ensembl chr 5:159,561,271...159,742,778 		JBrowse link
G Pgm1 phosphoglucomutase 1 increases expression ISO Antimony Potassium Tartrate results in increased expression of PGM1 mRNA CTD PMID:28713220 NCBI chr 5:114,595,298...114,654,728
Ensembl chr 5:114,595,293...114,654,728 		JBrowse link
G Pgm3 phosphoglucomutase 3 increases expression ISO Antimony Potassium Tartrate results in increased expression of PGM3 mRNA CTD PMID:28713220 NCBI chr 8:87,517,931...87,536,034
Ensembl chr 8:87,517,701...87,536,022 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of PIK3R1 mRNA CTD PMID:32076005 NCBI chr 2:32,878,942...32,963,611
Ensembl chr 2:32,882,032...32,963,631 		JBrowse link
G Pik3r2 phosphoinositide-3-kinase regulatory subunit 2 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of PIK3R2 mRNA CTD PMID:32076005 NCBI chr16:18,665,517...18,674,067
Ensembl chr16:18,665,457...18,674,065 		JBrowse link
G Pir pirin multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of PIR mRNA CTD PMID:32076005 NCBI chr  X:30,108,536...30,219,269
Ensembl chr  X:30,108,538...30,219,218 		JBrowse link
G Pitx1 paired-like homeodomain 1 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of PITX1 mRNA CTD PMID:32076005 NCBI chr17:8,794,134...8,800,292
Ensembl chr17:8,794,134...8,800,291 		JBrowse link
G Pml PML nuclear body scaffold affects localization
multiple interactions
increases degradation		 ISO Antimony Potassium Tartrate affects the localization of PML protein
Antimony Potassium Tartrate promotes the reaction [SUMO1 protein binds to PML protein]
Antimony Potassium Tartrate results in increased degradation of PML protein mutant form		 CTD PMID:9834237 NCBI chr 8:58,627,347...58,661,927
Ensembl chr 8:58,628,837...58,658,971 		JBrowse link
G Ppih peptidylprolyl isomerase H increases expression ISO Antimony Potassium Tartrate results in increased expression of PPIH mRNA CTD PMID:17547211 NCBI chr 5:132,906,324...132,924,341
Ensembl chr 5:132,906,328...132,924,267 		JBrowse link
G Prdx1 peroxiredoxin 1 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of PRDX1 mRNA CTD PMID:32076005 NCBI chr 5:130,147,276...130,162,850
Ensembl chr 5:130,147,204...130,162,856 		JBrowse link
G Psph phosphoserine phosphatase decreases expression ISO Antimony Potassium Tartrate results in decreased expression of PSPH mRNA CTD PMID:17547211 NCBI chr12:26,882,524...26,905,084
Ensembl chr12:26,883,133...26,905,074 		JBrowse link
G Pttg1 PTTG1 regulator of sister chromatid separation, securin increases expression ISO Antimony Potassium Tartrate results in increased expression of PTTG1 mRNA CTD PMID:17547211 NCBI chr10:27,893,466...27,904,965
Ensembl chr10:27,893,689...27,904,837 		JBrowse link
G Rara retinoic acid receptor, alpha increases degradation ISO Antimony Potassium Tartrate results in increased degradation of RARA protein mutant form CTD PMID:9834237 NCBI chr10:83,883,490...83,928,932
Ensembl chr10:83,893,384...83,928,142 		JBrowse link
G Rbpms RNA binding protein, mRNA processing factor increases expression ISO Antimony Potassium Tartrate results in increased expression of RBPMS mRNA CTD PMID:17547211 NCBI chr16:58,239,370...58,395,424
Ensembl chr16:58,239,474...58,395,426 		JBrowse link
G Rfc2 replication factor C subunit 2 increases expression ISO Antimony Potassium Tartrate results in increased expression of RFC2 mRNA CTD PMID:17547211 NCBI chr12:22,120,449...22,133,576
Ensembl chr12:22,120,010...22,133,557 		JBrowse link
G Rnaseh2a ribonuclease H2, subunit A increases expression ISO Antimony Potassium Tartrate results in increased expression of RNASEH2A mRNA CTD PMID:17547211 NCBI chr19:23,186,325...23,196,045
Ensembl chr19:23,186,383...23,196,041 		JBrowse link
G Rnh1 ribonuclease/angiogenin inhibitor 1 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of RNH1 protein CTD PMID:28713220 NCBI chr 1:196,269,293...196,281,763
Ensembl chr 1:196,269,293...196,281,910 		JBrowse link
G Rptn repetin decreases expression ISO Antimony Potassium Tartrate results in decreased expression of RPTN mRNA CTD PMID:28713220 NCBI chr 2:179,061,768...179,066,056
Ensembl chr 2:179,060,017...179,065,910 		JBrowse link
G Ryr1 ryanodine receptor 1 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of RYR1 mRNA CTD PMID:28713220 NCBI chr 1:84,292,578...84,423,799
Ensembl chr 1:84,292,578...84,423,812 		JBrowse link
G S100a2 S100 calcium binding protein A2 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of S100A2 mRNA CTD PMID:28713220 NCBI chr 2:176,075,060...176,078,782 JBrowse link
G S100a8 S100 calcium binding protein A8 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of S100A8 mRNA; Antimony Potassium Tartrate results in decreased expression of S100A8 protein CTD PMID:28713220 NCBI chr 2:176,166,517...176,167,645
Ensembl chr 2:176,167,124...176,167,643 		JBrowse link
G S100a9 S100 calcium binding protein A9 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of S100A9 mRNA; Antimony Potassium Tartrate results in decreased expression of S100A9 protein CTD PMID:28713220 NCBI chr 2:176,190,361...176,193,182
Ensembl chr 2:176,190,361...176,193,230 		JBrowse link
G Scd stearoyl-CoA desaturase decreases expression ISO Antimony Potassium Tartrate results in decreased expression of SCD mRNA CTD PMID:17547211 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562 		JBrowse link
G Sephs2 selenophosphate synthetase 2 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of SEPHS2 mRNA CTD PMID:17547211 NCBI chr 1:181,893,146...181,895,464
Ensembl chr 1:181,892,599...181,895,497 		JBrowse link
G Serpinb1a serpin family B member 1A decreases expression ISO Antimony Potassium Tartrate results in decreased expression of SERPINB1 mRNA CTD PMID:17547211 NCBI chr17:31,590,695...31,599,102
Ensembl chr17:31,590,677...31,599,102 		JBrowse link
G Serpinc1 serpin family C member 1 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of SERPINC1 mRNA CTD PMID:17547211 NCBI chr13:73,257,208...73,271,476
Ensembl chr13:73,257,179...73,284,293 		JBrowse link
G Serpine1 serpin family E member 1 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of SERPINE1 mRNA CTD PMID:32076005 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657 		JBrowse link
G Sik1 salt-inducible kinase 1 increases expression ISO Antimony Potassium Tartrate results in increased expression of SIK1 mRNA CTD PMID:17547211 NCBI chr20:9,949,407...9,959,036
Ensembl chr20:9,947,396...9,958,991 		JBrowse link
G Slc2a3 solute carrier family 2 member 3 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of SLC2A3 mRNA CTD PMID:32076005 NCBI chr 4:155,960,944...156,026,000
Ensembl chr 4:155,960,946...156,025,472 		JBrowse link
G Snrpa small nuclear ribonucleoprotein polypeptide A increases expression ISO Antimony Potassium Tartrate results in increased expression of SNRPA mRNA CTD PMID:17547211 NCBI chr 1:82,481,770...82,490,540
Ensembl chr 1:82,481,770...82,490,538 		JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of SOD1 mRNA CTD PMID:32076005 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Sprr1a small proline-rich protein 1A decreases expression ISO Antimony Potassium Tartrate results in decreased expression of SPRR1A mRNA; Antimony Potassium Tartrate results in decreased expression of SPRR1A protein CTD PMID:28713220 NCBI chr 2:178,055,096...178,057,012
Ensembl chr 2:178,055,096...178,057,063 		JBrowse link
G Sprr1b small proline-rich protein 1B decreases expression ISO Antimony Potassium Tartrate results in decreased expression of SPRR1B mRNA; Antimony Potassium Tartrate results in decreased expression of SPRR1B protein CTD PMID:28713220 NCBI chr 2:178,009,130...178,009,567
Ensembl chr 2:178,009,130...178,009,567 		JBrowse link
G Sprr3 small proline-rich protein 3 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of SPRR3 mRNA; Antimony Potassium Tartrate results in decreased expression of SPRR3 protein CTD PMID:28713220 NCBI chr 2:178,027,743...178,028,501
Ensembl chr 2:178,027,425...178,029,891 		JBrowse link
G Sqle squalene epoxidase decreases expression ISO Antimony Potassium Tartrate results in decreased expression of SQLE mRNA CTD PMID:17547211 NCBI chr 7:90,867,973...90,883,623
Ensembl chr 7:90,868,011...90,883,618 		JBrowse link
G Sqstm1 sequestosome 1 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of SQSTM1 mRNA CTD PMID:32076005 NCBI chr10:34,525,517...34,536,685
Ensembl chr10:34,525,519...34,536,673 		JBrowse link
G Srsf1 serine and arginine rich splicing factor 1 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of SRSF1 mRNA CTD PMID:17547211 NCBI chr10:72,838,926...72,859,066
Ensembl chr10:72,839,274...72,845,336 		JBrowse link
G Srsf5 serine and arginine rich splicing factor 5 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of SRSF5 mRNA CTD PMID:17547211 NCBI chr 6:100,605,165...100,610,192
Ensembl chr 6:100,605,456...100,610,177 		JBrowse link
G Srxn1 sulfiredoxin 1 increases expression ISO Antimony Potassium Tartrate results in increased expression of SRXN1 mRNA CTD PMID:28713220 NCBI chr 3:140,604,490...140,610,050
Ensembl chr 3:140,599,608...140,628,448 		JBrowse link
G St6galnac4 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of ST6GALNAC4 mRNA CTD PMID:17547211 NCBI chr 3:15,872,230...15,885,250
Ensembl chr 3:15,872,532...15,885,243 		JBrowse link
G Stat1 signal transducer and activator of transcription 1 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] inhibits the reaction [OSM protein results in increased phosphorylation of STAT1 protein]; [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of STAT1 mRNA CTD PMID:32076005 NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540 		JBrowse link
G Sult1c3 sulfotransferase family 1C member 3 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of SULT1C3 mRNA CTD PMID:32076005 NCBI chr 9:7,221,580...7,266,991
Ensembl chr 9:7,221,578...7,267,030 		JBrowse link
G Sult1e1 sulfotransferase family 1E member 1 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of SULT1E1 mRNA CTD PMID:32076005 NCBI chr14:20,422,324...20,439,562
Ensembl chr14:20,422,324...20,439,275 		JBrowse link
G Sult2b1 sulfotransferase family 2B member 1 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of SULT2B1 mRNA CTD PMID:32076005 NCBI chr 1:96,200,155...96,261,295
Ensembl chr 1:96,200,156...96,261,295 		JBrowse link
G Sumo1 small ubiquitin-like modifier 1 affects localization
multiple interactions		 ISO Antimony Potassium Tartrate affects the localization of SUMO1 protein
Antimony Potassium Tartrate promotes the reaction [SUMO1 protein binds to PML protein]		 CTD PMID:9834237 NCBI chr 9:61,078,790...61,108,697
Ensembl chr 9:61,077,435...61,108,761 		JBrowse link
G Tardbp TAR DNA binding protein decreases expression ISO Antimony Potassium Tartrate results in decreased expression of TARDBP mRNA CTD PMID:17547211 NCBI chr 5:159,050,518...159,062,218
Ensembl chr 5:159,051,799...159,062,055 		JBrowse link
G Tgm1 transglutaminase 1 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of TGM1 mRNA CTD PMID:32076005 NCBI chr15:29,191,039...29,206,000
Ensembl chr15:29,191,041...29,204,523 		JBrowse link
G Tnfaip3 TNF alpha induced protein 3 increases expression ISO Antimony Potassium Tartrate results in increased expression of TNFAIP3 mRNA CTD PMID:17547211 NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282 		JBrowse link
G Tnfsf10 TNF superfamily member 10 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of TNFSF10 mRNA CTD PMID:17547211 NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135 		JBrowse link
G Tob1 transducer of ErbB-2.1 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of TOB1 mRNA CTD PMID:17547211 NCBI chr10:79,163,093...79,165,131
Ensembl chr10:79,160,154...79,165,215 		JBrowse link
G Tp63 tumor protein p63 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of TP63 mRNA CTD PMID:32076005 NCBI chr11:74,838,858...75,049,764
Ensembl chr11:74,838,859...75,049,398 		JBrowse link
G Tpi1 triosephosphate isomerase 1 increases expression ISO Antimony Potassium Tartrate results in increased expression of TPI1 mRNA CTD PMID:28713220 NCBI chr 4:157,615,283...157,618,813
Ensembl chr 4:157,615,386...157,619,541 		JBrowse link
G Tsc22d3 TSC22 domain family, member 3 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of TSC22D3 mRNA CTD PMID:32076005 NCBI chr  X:104,217,898...104,277,935
Ensembl chr  X:104,217,925...104,276,861 		JBrowse link
G Tspan7 tetraspanin 7 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of TSPAN7 mRNA CTD PMID:17547211 NCBI chr  X:12,208,783...12,306,160
Ensembl chr  X:12,208,783...12,306,131 		JBrowse link
G Tuft1 tuftelin 1 increases expression ISO Antimony Potassium Tartrate results in increased expression of TUFT1 mRNA CTD PMID:17547211 NCBI chr 2:182,259,457...182,306,296
Ensembl chr 2:182,260,398...182,306,192 		JBrowse link
G Txn1 thioredoxin 1 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of TXN mRNA CTD PMID:32076005 NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629 		JBrowse link
G Txnrd1 thioredoxin reductase 1 increases expression
multiple interactions		 ISO Antimony Potassium Tartrate results in increased expression of TXNRD1 mRNA
[Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of TXNRD1 mRNA		 CTD PMID:17547211 PMID:28713220 PMID:32076005 NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863 		JBrowse link
G Tyms thymidylate synthetase increases expression ISO Antimony Potassium Tartrate results in increased expression of TYMS mRNA CTD PMID:17547211 NCBI chr 9:113,313,454...113,329,551
Ensembl chr 9:113,313,452...113,329,536 		JBrowse link
G Ube2c ubiquitin-conjugating enzyme E2C increases expression ISO Antimony Potassium Tartrate results in increased expression of UBE2C mRNA CTD PMID:17547211 NCBI chr 3:153,506,636...153,509,036
Ensembl chr 3:153,506,636...153,513,339 		JBrowse link
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 multiple interactions
increases expression		 ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of UGT1A6 mRNA
Antimony Potassium Tartrate results in increased expression of UGT1A6 mRNA		 CTD PMID:28713220 PMID:32076005 NCBI chr 9:88,747,229...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Zwint ZW10 interacting kinetochore protein increases expression ISO Antimony Potassium Tartrate results in increased expression of ZWINT mRNA CTD PMID:17547211 NCBI chr20:15,938,157...15,953,997
Ensembl chr20:15,938,157...15,953,957 		JBrowse link
diprotium oxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agrp agouti related neuropeptide multiple interactions EXP [Water deficiency co-treated with Sodium Chloride, Dietary deficiency] results in increased expression of AGRP mRNA; AM 251 promotes the reaction [[Water deficiency co-treated with Sodium Chloride, Dietary deficiency] results in increased expression of AGRP mRNA] CTD PMID:26468265 NCBI chr19:33,447,992...33,523,068
Ensembl chr19:33,447,992...33,449,584 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO [[Particulate Matter co-treated with Water] results in increased abundance of Metals] which results in increased expression of AKT1 mRNA CTD PMID:29335169 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Aqp1 aquaporin 1 increases transport
multiple interactions		 ISO
EXP		 AQP1 protein results in increased transport of Water
Mercuric Chloride inhibits the reaction [AQP1 protein results in increased transport of Water]; Mercury inhibits the reaction [AQP1 protein results in increased transport of Water]		 CTD PMID:7528928 PMID:8457558 PMID:10559675 PMID:11035042 PMID:11078688 More... NCBI chr 4:84,482,512...84,494,690
Ensembl chr 4:84,482,512...84,494,690 		JBrowse link
G Aqp11 aquaporin 11 multiple interactions
increases transport		 ISO Mercaptoethanol inhibits the reaction [Mercuric Chloride inhibits the reaction [AQP11 protein results in increased transport of Water]]; Mercuric Chloride inhibits the reaction [AQP11 protein results in increased transport of Water] CTD PMID:21251984 NCBI chr 1:152,046,515...152,056,675
Ensembl chr 1:152,046,517...152,056,725 		JBrowse link
G Aqp2 aquaporin 2 increases expression EXP Water deficiency results in increased expression of AQP2 mRNA CTD PMID:15462210 NCBI chr 7:130,711,433...130,716,468
Ensembl chr 7:130,711,413...130,716,468 		JBrowse link
G Aqp3 aquaporin 3 (Gill blood group) multiple interactions
increases expression
increases transport		 ISO
EXP		 Dexamethasone promotes the reaction [AQP3 protein results in increased transport of Water]; Mercaptoethanol inhibits the reaction [Mercuric Chloride inhibits the reaction [AQP3 protein results in increased transport of Water]]; Mercuric Chloride inhibits the reaction [AQP3 protein results in increased transport of Water]; Mercuric Chloride inhibits the reaction [Dexamethasone promotes the reaction [AQP3 protein results in increased transport of Water]]
Water deficiency results in increased expression of AQP3 mRNA; Water deficiency results in increased expression of AQP3 protein
Copper Sulfate inhibits the reaction [AQP3 protein results in increased transport of Water]; Mercuric Chloride inhibits the reaction [AQP3 protein results in increased transport of Water]		 CTD PMID:9124401 PMID:9374739 PMID:15462210 PMID:22687538 NCBI chr 5:56,239,200...56,244,718
Ensembl chr 5:56,239,201...56,244,720 		JBrowse link
G Aqp4 aquaporin 4 increases transport
increases response to substance
increases expression
affects transport		 EXP
ISO		 AQP4 protein results in increased transport of Water
AQP4 protein results in increased susceptibility to Water
Water deficiency results in increased expression of AQP4 mRNA
AQP4 protein affects the transport of Water		 CTD PMID:7528931 PMID:15462210 PMID:20815926 PMID:21251984 NCBI chr18:6,507,903...6,524,558
Ensembl chr18:6,507,903...6,524,856 		JBrowse link
G Aqp7 aquaporin 7 affects transport
increases transport		 EXP AQP7 protein affects the transport of Water
AQP7 protein results in increased transport of Water		 CTD PMID:9252401 PMID:18059526 NCBI chr 5:56,171,649...56,186,642
Ensembl chr 5:56,172,519...56,186,642 		JBrowse link
G Aqp8 aquaporin 8 multiple interactions
increases transport
affects transport		 EXP
ISO		 Copper affects the reaction [AQP8 protein affects the transport of Water]; Mercury affects the reaction [AQP8 protein affects the transport of Water]
AQP8 protein results in increased transport of Water
Mercuric Chloride inhibits the reaction [AQP8 protein results in increased transport of Water]		 CTD PMID:18059526 PMID:19840149 NCBI chr 1:177,993,313...177,999,158
Ensembl chr 1:177,993,305...177,999,158 		JBrowse link
G Aqp9 aquaporin 9 multiple interactions
increases transport
affects transport		 EXP
ISO		 CFTR protein promotes the reaction [AQP9 protein affects the transport of Water]; lonidamine inhibits the reaction [CFTR protein promotes the reaction [AQP9 protein affects the transport of Water]]; Mercuric Chloride inhibits the reaction [AQP9 protein results in increased transport of Water]; Mercury inhibits the reaction [AQP9 protein results in increased transport of Water]; Phloretin inhibits the reaction [AQP9 protein results in increased transport of Water]; Phloretin inhibits the reaction [CFTR protein promotes the reaction [AQP9 protein affects the transport of Water]] CTD PMID:9514918 PMID:9733774 PMID:10205677 PMID:12606488 PMID:21259319 More... NCBI chr 8:71,797,231...71,837,485
Ensembl chr 8:71,797,234...71,837,395 		JBrowse link
G Avp arginine vasopressin multiple interactions EXP [Water deficiency co-treated with Sodium Chloride, Dietary deficiency] results in increased expression of AVP mRNA; [Water deficiency co-treated with Sodium Chloride, Dietary deficiency] results in increased secretion of AVP protein; AM 251 promotes the reaction [[Water deficiency co-treated with Sodium Chloride, Dietary deficiency] results in increased expression of AVP mRNA]; arachidonyl-2-chloroethylamide inhibits the reaction [[Water deficiency co-treated with Sodium Chloride, Dietary deficiency] results in increased expression of AVP mRNA] CTD PMID:26468265 NCBI chr 3:117,793,447...117,805,091
Ensembl chr 3:117,793,457...117,795,425 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO [[Particulate Matter co-treated with Water] results in increased abundance of Metals] which results in increased expression of BCL2 mRNA CTD PMID:29335169 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Cartpt CART prepropeptide multiple interactions EXP [AM 251 co-treated with Water deficiency co-treated with Sodium Chloride, Dietary deficiency] results in increased expression of CARTPT mRNA; [arachidonyl-2-chloroethylamide co-treated with Water deficiency co-treated with Sodium Chloride, Dietary deficiency] results in increased expression of CARTPT mRNA CTD PMID:26468265 NCBI chr 2:31,255,098...31,257,452
Ensembl chr 2:31,255,098...31,290,713 		JBrowse link
G Casp1 caspase 1 multiple interactions ISO [[Particulate Matter co-treated with Water] results in increased abundance of Metals] which affects the expression of CASP1 mRNA CTD PMID:29335169 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383 		JBrowse link
G Casp3 caspase 3 multiple interactions EXP [Water deficiency co-treated with Diclofenac] results in increased expression of CASP3 protein; Gum Arabic inhibits the reaction [[Water deficiency co-treated with Diclofenac] results in increased expression of CASP3 protein] CTD PMID:31042592 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Cat catalase multiple interactions EXP
ISO		 [Water deficiency co-treated with Diclofenac] results in decreased activity of CAT protein; Gum Arabic inhibits the reaction [[Water deficiency co-treated with Diclofenac] results in decreased activity of CAT protein]
[[Particulate Matter co-treated with Water] results in increased abundance of Metals] which results in increased expression of CAT mRNA		 CTD PMID:29335169 PMID:31042592 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions EXP [Water deficiency co-treated with Diclofenac] results in increased expression of CCL2 protein; Gum Arabic inhibits the reaction [[Water deficiency co-treated with Diclofenac] results in increased expression of CCL2 protein] CTD PMID:31042592 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Cftr CF transmembrane conductance regulator multiple interactions EXP 1-Methyl-3-isobutylxanthine promotes the reaction [CFTR protein affects the transport of Water]; CFTR protein promotes the reaction [AQP9 protein affects the transport of Water]; lonidamine inhibits the reaction [CFTR protein promotes the reaction [AQP9 protein affects the transport of Water]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [CFTR protein affects the transport of Water]; Phloretin inhibits the reaction [CFTR protein promotes the reaction [AQP9 protein affects the transport of Water]] CTD PMID:12606488 NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756 		JBrowse link
G Cnr1 cannabinoid receptor 1 multiple interactions EXP [Water deficiency co-treated with Sodium Chloride, Dietary deficiency] results in increased expression of CNR1 mRNA; [Water deficiency co-treated with Sodium Chloride, Dietary deficiency] results in increased expression of CNR1 protein CTD PMID:26468265 NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099 		JBrowse link
G Col3a1 collagen type III alpha 1 chain multiple interactions EXP [Water deficiency co-treated with Diclofenac] results in increased expression of COL3A1 protein; Gum Arabic inhibits the reaction [[Water deficiency co-treated with Diclofenac] results in increased expression of COL3A1 protein] CTD PMID:31042592 NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547 		JBrowse link
G Cr1l complement C3b/C4b receptor 1 like multiple interactions EXP [Water deficiency co-treated with Diclofenac] results in decreased expression of CR1L protein; Gum Arabic inhibits the reaction [[Water deficiency co-treated with Diclofenac] results in decreased expression of CR1L protein] CTD PMID:31042592 NCBI chr13:106,606,952...106,660,442
Ensembl chr13:106,574,858...106,660,445 		JBrowse link
G Crh corticotropin releasing hormone multiple interactions EXP [AM 251 co-treated with Water deficiency co-treated with Sodium Chloride, Dietary deficiency] results in increased expression of CRH mRNA CTD PMID:26468265 NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO [[Particulate Matter co-treated with Water] results in increased abundance of Metals] which results in decreased expression of CYP1A1 mRNA CTD PMID:29335169 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions ISO [[Particulate Matter co-treated with Water] results in increased abundance of Metals] which results in decreased expression of CYP2E1 mRNA CTD PMID:29335169 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Edn1 endothelin 1 affects export ISO EDN1 protein affects the export of Water CTD PMID:16340664 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Fgf2 fibroblast growth factor 2 increases expression ISO Water results in increased expression of FGF2 mRNA CTD PMID:26800359 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions ISO [[Particulate Matter co-treated with Water] results in increased abundance of Metals] which results in increased expression of GCLC mRNA CTD PMID:29335169 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544 		JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions ISO [[Particulate Matter co-treated with Water] results in increased abundance of Metals] which results in increased expression of GPX1 mRNA CTD PMID:29335169 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions ISO [[Particulate Matter co-treated with Water] results in increased abundance of Metals] which results in increased expression of GSR mRNA CTD PMID:29335169 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661 		JBrowse link
G Hbegf heparin-binding EGF-like growth factor decreases expression ISO Water results in decreased expression of HBEGF mRNA CTD PMID:26800359 NCBI chr18:28,106,284...28,116,167
Ensembl chr18:28,105,760...28,116,441 		JBrowse link
G Hcrt hypocretin neuropeptide precursor multiple interactions EXP [Water deficiency co-treated with Sodium Chloride, Dietary deficiency] results in increased expression of HCRT mRNA; AM 251 inhibits the reaction [[Water deficiency co-treated with Sodium Chloride, Dietary deficiency] results in increased expression of HCRT mRNA] CTD PMID:26468265 NCBI chr10:85,689,992...85,691,206
Ensembl chr10:85,689,465...85,691,210 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions		 EXP
ISO		 Water deficiency results in increased expression of HMOX1 protein
[[Particulate Matter co-treated with Water] results in increased abundance of Metals] which results in increased expression of HMOX1 mRNA		 CTD PMID:22060896 PMID:29335169 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hpgds hematopoietic prostaglandin D synthase multiple interactions ISO Water affects the reaction [Isoquinolines analog binds to and results in decreased activity of HPGDS protein] CTD PMID:22546671 NCBI chr 4:94,368,426...94,397,931
Ensembl chr 4:94,373,342...94,397,883 		JBrowse link
G Il10 interleukin 10 multiple interactions EXP [Gum Arabic co-treated with Water deficiency co-treated with Diclofenac] results in increased expression of IL10 protein CTD PMID:31042592 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP
ISO		 [Water deficiency co-treated with Diclofenac] results in increased expression of IL1B protein; Gum Arabic inhibits the reaction [[Water deficiency co-treated with Diclofenac] results in increased expression of IL1B protein]
[[Particulate Matter co-treated with Water] results in increased abundance of Metals] which results in increased expression of IL1B mRNA		 CTD PMID:29335169 PMID:31042592 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Mt2A metallothionein 2A multiple interactions ISO [[Particulate Matter co-treated with Water] results in increased abundance of Metals] which affects the expression of MT2 mRNA CTD PMID:29335169 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions ISO [[Particulate Matter co-treated with Water] results in increased abundance of Metals] which results in increased expression of NFE2L2 mRNA CTD PMID:29335169 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO [[Particulate Matter co-treated with Water] results in increased abundance of Metals] which results in increased expression of NOS2 mRNA CTD PMID:29335169 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Npy neuropeptide Y multiple interactions EXP [AM 251 co-treated with Water deficiency co-treated with Sodium Chloride, Dietary deficiency] results in increased expression of NPY mRNA CTD PMID:26468265 NCBI chr 4:78,881,294...78,888,495
Ensembl chr 4:78,881,264...78,888,495 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions ISO [[Particulate Matter co-treated with Water] results in increased abundance of Metals] which results in increased expression of NQO1 mRNA CTD PMID:29335169 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Oxt oxytocin/neurophysin I prepropeptide multiple interactions EXP [Water deficiency co-treated with Sodium Chloride, Dietary deficiency] results in increased expression of OXT mRNA; [Water deficiency co-treated with Sodium Chloride, Dietary deficiency] results in increased secretion of OXT protein; AM 251 promotes the reaction [[Water deficiency co-treated with Sodium Chloride, Dietary deficiency] results in increased expression of OXT mRNA]; arachidonyl-2-chloroethylamide inhibits the reaction [[Water deficiency co-treated with Sodium Chloride, Dietary deficiency] results in increased expression of OXT mRNA]; arachidonyl-2-chloroethylamide inhibits the reaction [[Water deficiency co-treated with Sodium Chloride, Dietary deficiency] results in increased secretion of OXT protein] CTD PMID:26468265 NCBI chr 3:117,782,650...117,783,490
Ensembl chr 3:117,782,650...117,783,490 		JBrowse link
G Pmch pro-melanin-concentrating hormone multiple interactions EXP [Water deficiency co-treated with Sodium Chloride, Dietary deficiency] results in increased expression of PMCH mRNA; arachidonyl-2-chloroethylamide promotes the reaction [[Water deficiency co-treated with Sodium Chloride, Dietary deficiency] results in increased expression of PMCH mRNA] CTD PMID:26468265 NCBI chr 7:22,511,934...22,513,250
Ensembl chr 7:22,511,934...22,513,250 		JBrowse link
G Pomc proopiomelanocortin multiple interactions EXP [Water deficiency co-treated with Sodium Chloride, Dietary deficiency] results in increased expression of POMC mRNA; AM 251 promotes the reaction [[Water deficiency co-treated with Sodium Chloride, Dietary deficiency] results in increased expression of POMC mRNA]; arachidonyl-2-chloroethylamide inhibits the reaction [[Water deficiency co-treated with Sodium Chloride, Dietary deficiency] results in increased expression of POMC mRNA] CTD PMID:26468265 NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664 		JBrowse link
G Slc12a1 solute carrier family 12 member 1 multiple interactions
increases import		 EXP [Glucose results in increased activity of SLC12A1 protein] which results in increased import of Water; [Mannitol results in increased activity of SLC12A1 protein] which results in increased import of Water
SLC12A1 protein results in increased import of Water		 CTD PMID:12433675 NCBI chr 3:112,406,140...112,482,913
Ensembl chr 3:112,406,140...112,482,899 		JBrowse link
G Slc5a3 solute carrier family 5 member 3 increases expression ISO Water deficiency results in increased expression of SLC5A3 mRNA CTD PMID:21219332 NCBI chr11:31,313,847...31,316,293
Ensembl chr11:31,295,476...31,318,883 		JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions ISO [[Particulate Matter co-treated with Water] results in increased abundance of Metals] which results in increased expression of SOD1 mRNA CTD PMID:29335169 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Sod2 superoxide dismutase 2 increases expression
multiple interactions		 ISO Water deficiency results in increased expression of SOD2 protein
[[Particulate Matter co-treated with Water] results in increased abundance of Metals] which results in increased expression of SOD2 mRNA		 CTD PMID:22718889 PMID:29335169 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Tac1 tachykinin, precursor 1 multiple interactions EXP TAC1 protein alternative form inhibits the reaction [Cholera Toxin results in increased secretion of Water]; TAC1 protein inhibits the reaction [Cholera Toxin results in increased secretion of Water] CTD PMID:11040190 NCBI chr 4:35,679,183...35,687,180
Ensembl chr 4:35,679,704...35,687,178 		JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP [Water deficiency co-treated with Diclofenac] results in increased expression of TNF protein; Gum Arabic inhibits the reaction [[Water deficiency co-treated with Diclofenac] results in increased expression of TNF protein] CTD PMID:31042592 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
enalaprilat dihydrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme multiple interactions ISO Enalaprilat inhibits the reaction [Glucose results in increased expression of ACE protein] CTD PMID:16452552 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131 		JBrowse link
G Adrb1 adrenoceptor beta 1 affects expression EXP Enalaprilat affects the expression of ADRB1 protein CTD PMID:9260993 NCBI chr 1:255,772,217...255,773,617
Ensembl chr 1:255,771,597...255,807,259 		JBrowse link
G Adrb2 adrenoceptor beta 2 affects expression EXP Enalaprilat affects the expression of ADRB2 protein CTD PMID:9260993 NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512 		JBrowse link
G Agt angiotensinogen decreases expression
multiple interactions		 EXP
ISO		 Enalaprilat results in decreased expression of AGT protein modified form
Enalaprilat inhibits the reaction [Glucose results in increased expression of AGT protein]		 CTD PMID:16452552 PMID:21795644 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977 		JBrowse link
G Agtr1a angiotensin II receptor, type 1a multiple interactions ISO Enalaprilat inhibits the reaction [Glucose results in increased expression of AGTR1 protein] CTD PMID:16452552 NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946 		JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression ISO Enalaprilat results in increased expression of BCL2 mRNA CTD PMID:17342403 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bdkrb1 bradykinin receptor B1 multiple interactions
increases activity		 ISO bradykinin, Lys-Leu(8)-desArg(9)- inhibits the reaction [Enalaprilat results in increased activity of BDKRB1 protein]; Zinc affects the reaction [Enalaprilat results in increased activity of BDKRB1 protein] CTD PMID:11880373 NCBI chr 6:124,510,827...124,514,475
Ensembl chr 6:124,510,870...124,513,747 		JBrowse link
G Edn1 endothelin 1 decreases secretion ISO Enalaprilat results in decreased secretion of EDN1 protein CTD PMID:19079593 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Fn1 fibronectin 1 decreases expression
multiple interactions		 EXP
ISO		 Enalaprilat results in decreased expression of FN1 mRNA; Enalaprilat results in decreased expression of FN1 protein
Enalaprilat inhibits the reaction [Glucose results in increased expression of FN1 mRNA]		 CTD PMID:14520012 PMID:21795644 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678 		JBrowse link
G Glud1 glutamate dehydrogenase 1 multiple interactions EXP Enalaprilat inhibits the reaction [Dexamethasone results in decreased expression of GLUD1 mRNA] CTD PMID:32494933 NCBI chr16:9,640,312...9,673,961
Ensembl chr16:9,640,312...9,673,957 		JBrowse link
G Grm1 glutamate metabotropic receptor 1 multiple interactions EXP Enalaprilat inhibits the reaction [Dexamethasone results in increased expression of GRM1 mRNA] CTD PMID:32494933 NCBI chr 1:5,058,285...5,453,170
Ensembl chr 1:5,058,292...5,453,170 		JBrowse link
G Hmgb1 high mobility group box 1 multiple interactions EXP Enalaprilat inhibits the reaction [Dexamethasone results in increased expression of HMGB1 mRNA]; Enalaprilat inhibits the reaction [Dexamethasone results in increased expression of HMGB1 protein] CTD PMID:32494933 NCBI chr12:5,973,062...5,978,565
Ensembl chr12:5,901,586...5,978,565 		JBrowse link
G Ins2 insulin 2 multiple interactions ISO Enalaprilat inhibits the reaction [Glucose results in decreased secretion of INS protein] CTD PMID:16452552 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775 		JBrowse link
G Ppard peroxisome proliferator-activated receptor delta multiple interactions EXP [Enalaprilat co-treated with Daunorubicin] results in increased expression of PPARD mRNA CTD PMID:23834779 NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968 		JBrowse link
G Ren renin increases expression EXP Enalaprilat results in increased expression of REN mRNA CTD PMID:21795644 NCBI chr13:44,796,260...44,807,491
Ensembl chr13:44,796,091...44,807,489 		JBrowse link
G Serpine1 serpin family E member 1 decreases expression EXP Enalaprilat results in decreased expression of SERPINE1 mRNA CTD PMID:21795644 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 decreases expression EXP Enalaprilat results in decreased expression of TGFB1 mRNA; Enalaprilat results in decreased expression of TGFB1 protein CTD PMID:21795644 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions EXP Enalaprilat inhibits the reaction [Dexamethasone results in increased expression of TLR4 mRNA] CTD PMID:32494933 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tnf tumor necrosis factor decreases expression ISO Enalaprilat results in decreased expression of TNF mRNA CTD PMID:17342403 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
gadodiamide hydrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 increases phosphorylation
multiple interactions		 ISO gadodiamide results in increased phosphorylation of AKT1 protein
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [gadodiamide results in increased phosphorylation of AKT1 protein]		 CTD PMID:19561517 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 increases expression ISO gadodiamide results in increased expression of ALDH1A1 mRNA CTD PMID:20959327 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961 		JBrowse link
G Ankrd22 ankyrin repeat domain 22 increases expression ISO gadodiamide results in increased expression of ANKRD22 mRNA CTD PMID:20959327 NCBI chr 1:231,639,035...231,670,537
Ensembl chr 1:231,639,314...231,670,381 		JBrowse link
G Atm ATM serine/threonine kinase increases expression ISO gadodiamide results in increased expression of ATM mRNA CTD PMID:20959327 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437 		JBrowse link
G Atp8b1 ATPase phospholipid transporting 8B1 increases expression ISO gadodiamide results in increased expression of ATP8B1 mRNA CTD PMID:20959327 NCBI chr18:58,016,382...58,157,213
Ensembl chr18:58,018,268...58,157,396 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression
increases secretion		 ISO
EXP		 gadodiamide results in increased expression of CCL2 mRNA
gadodiamide results in increased expression of CCL2 mRNA; gadodiamide results in increased expression of CCL2 protein
gadodiamide results in increased secretion of CCL2 protein		 CTD PMID:20938346 PMID:20959327 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccl4 C-C motif chemokine ligand 4 increases expression EXP gadodiamide results in increased expression of CCL4 protein CTD PMID:20938346 NCBI chr10:68,466,469...68,467,941
Ensembl chr10:68,452,052...68,468,231 		JBrowse link
G Ccl7 C-C motif chemokine ligand 7 increases expression EXP gadodiamide results in increased expression of CCL7 protein CTD PMID:20938346 NCBI chr10:67,016,446...67,018,296
Ensembl chr10:67,016,446...67,018,303 		JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 increases expression
increases secretion		 ISO
EXP		 gadodiamide results in increased expression of CXCL10 mRNA
gadodiamide results in increased expression of CXCL10 protein
gadodiamide results in increased secretion of CXCL10 protein		 CTD PMID:20938346 PMID:20959327 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975 		JBrowse link
G Cxcl11 C-X-C motif chemokine ligand 11 increases secretion
increases expression		 ISO gadodiamide results in increased secretion of CXCL11 protein
gadodiamide results in increased expression of CXCL11 mRNA		 CTD PMID:20959327 NCBI chr14:15,689,432...15,692,207
Ensembl chr14:15,689,424...15,692,271 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 increases expression ISO gadodiamide results in increased expression of CXCL12 mRNA CTD PMID:20959327 NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168 		JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 increases expression ISO gadodiamide results in increased expression of CXCL9 mRNA CTD PMID:20959327 NCBI chr14:15,722,868...15,727,779
Ensembl chr14:15,722,908...15,728,435 		JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 increases expression ISO gadodiamide results in increased expression of IDO1 mRNA CTD PMID:20959327 NCBI chr16:67,430,684...67,442,459
Ensembl chr16:67,430,578...67,442,730 		JBrowse link
G Ifi44l interferon-induced protein 44-like increases expression ISO gadodiamide results in increased expression of IFI44L mRNA CTD PMID:20959327 NCBI chr 2:240,668,742...240,706,425
Ensembl chr 2:240,668,713...240,706,359 		JBrowse link
G Ifit3 interferon-induced protein with tetratricopeptide repeats 3 increases expression ISO gadodiamide results in increased expression of IFIT3 mRNA CTD PMID:20959327 NCBI chr 1:232,114,166...232,119,311
Ensembl chr 1:232,114,166...232,119,307 		JBrowse link
G Ifng interferon gamma increases expression ISO gadodiamide results in increased expression of IFNG mRNA; gadodiamide results in increased expression of IFNG protein CTD PMID:19404939 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Il13 interleukin 13 increases expression ISO gadodiamide results in increased expression of IL13 mRNA; gadodiamide results in increased expression of IL13 protein CTD PMID:19404939 NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737 		JBrowse link
G Il1a interleukin 1 alpha increases expression EXP gadodiamide results in increased expression of IL1A protein CTD PMID:20938346 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Il4 interleukin 4 increases expression
affects expression		 ISO gadodiamide results in increased expression of IL4 protein
gadodiamide affects the expression of IL4 mRNA		 CTD PMID:19404939 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Il4i1 interleukin 4 induced 1 increases expression ISO gadodiamide results in increased expression of IL4I1 mRNA CTD PMID:20959327 NCBI chr 1:95,299,457...95,324,564
Ensembl chr 1:95,295,601...95,324,562 		JBrowse link
G Il6 interleukin 6 affects expression
increases expression		 ISO gadodiamide affects the expression of IL6 protein
gadodiamide results in increased expression of IL6 mRNA		 CTD PMID:19404939 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Kitlg KIT ligand increases expression EXP gadodiamide results in increased expression of KITLG protein CTD PMID:20938346 NCBI chr 7:34,896,075...34,977,215
Ensembl chr 7:34,896,053...34,977,214 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation		 ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [gadodiamide results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [gadodiamide results in increased phosphorylation of MAPK1 protein] CTD PMID:19561517 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation		 ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [gadodiamide results in increased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [gadodiamide results in increased phosphorylation of MAPK3 protein] CTD PMID:19561517 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mmp1 matrix metallopeptidase 1 multiple interactions
increases expression		 ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [gadodiamide results in increased expression of MMP1 protein]; U 0126 inhibits the reaction [gadodiamide results in increased expression of MMP1 protein]
gadodiamide results in increased expression of MMP1 mRNA; gadodiamide results in increased expression of MMP1 protein		 CTD PMID:19561517 NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097 		JBrowse link
G Nos2 nitric oxide synthase 2 increases expression ISO gadodiamide results in increased expression of NOS2 protein CTD PMID:20959327 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Nxpe3 neurexophilin and PC-esterase domain family, member 3 increases expression ISO gadodiamide results in increased expression of NXPE3 mRNA CTD PMID:20959327 NCBI chr11:44,726,905...44,777,694
Ensembl chr11:44,727,069...44,777,694 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit increases localization ISO gadodiamide results in increased localization of RELA protein CTD PMID:20959327 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G RGD1306063 similar to HT021 increases expression ISO gadodiamide results in increased expression of C3ORF14 mRNA CTD PMID:20959327 NCBI chr15:12,815,159...12,835,115
Ensembl chr15:12,818,385...12,833,838 		JBrowse link
G Rhoq ras homolog family member Q increases expression ISO gadodiamide results in increased expression of RHOQ mRNA CTD PMID:20959327 NCBI chr 6:7,613,632...7,652,047 JBrowse link
G Rit1 Ras-like without CAAX 1 increases expression ISO gadodiamide results in increased expression of RIT1 mRNA CTD PMID:20959327 NCBI chr 2:174,180,742...174,195,455
Ensembl chr 2:174,180,848...174,195,455 		JBrowse link
G Rnf125 ring finger protein 125 increases expression ISO gadodiamide results in increased expression of RNF125 mRNA CTD PMID:20959327 NCBI chr18:12,254,066...12,275,719
Ensembl chr18:12,253,852...12,275,983 		JBrowse link
G Rsad2 radical S-adenosyl methionine domain containing 2 increases expression ISO gadodiamide results in increased expression of RSAD2 mRNA CTD PMID:20959327 NCBI chr 6:43,046,514...43,059,737
Ensembl chr 6:43,047,658...43,059,699 		JBrowse link
G Slc39a10 solute carrier family 39 member 10 increases expression ISO gadodiamide results in increased expression of SLC39A10 mRNA CTD PMID:20959327 NCBI chr 9:54,836,841...54,960,325
Ensembl chr 9:54,876,141...54,960,325 		JBrowse link
G Spn sialophorin increases expression ISO gadodiamide results in increased expression of SPN mRNA CTD PMID:20959327 NCBI chr 1:181,746,937...181,759,564
Ensembl chr 1:181,746,429...181,759,628 		JBrowse link
G Spp1 secreted phosphoprotein 1 increases expression EXP gadodiamide results in increased expression of SPP1 protein CTD PMID:20938346 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 increases expression ISO
EXP		 gadodiamide results in increased expression of TGFB1 mRNA; gadodiamide results in increased expression of TGFB1 protein CTD PMID:19404939 PMID:20938346 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 increases expression
multiple interactions		 ISO
EXP		 gadodiamide results in increased expression of TIMP1 mRNA; gadodiamide results in increased expression of TIMP1 protein
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [gadodiamide results in increased expression of TIMP1 protein]; U 0126 inhibits the reaction [gadodiamide results in increased expression of TIMP1 protein]		 CTD PMID:19561517 PMID:20938346 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664 		JBrowse link
G Ubd ubiquitin D increases expression ISO gadodiamide results in increased expression of UBD mRNA CTD PMID:20959327 NCBI chr20:1,385,487...1,387,438
Ensembl chr20:1,385,864...1,408,639
Ensembl chr20:1,385,864...1,408,639 		JBrowse link
G Vegfa vascular endothelial growth factor A increases expression ISO
EXP		 gadodiamide results in increased expression of VEGFA mRNA; gadodiamide results in increased expression of VEGFA protein CTD PMID:19404939 PMID:20938346 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
G Wdr5 WD repeat domain 5 increases expression ISO gadodiamide results in increased expression of WDR5 mRNA CTD PMID:20959327 NCBI chr 3:10,836,964...10,856,682
Ensembl chr 3:10,837,025...10,856,671 		JBrowse link
G Xiap X-linked inhibitor of apoptosis increases expression ISO gadodiamide results in increased expression of XIAP mRNA CTD PMID:20959327 NCBI chr  X:120,890,537...120,938,413
Ensembl chr  X:120,897,907...120,934,700 		JBrowse link
G Zfp652 zinc finger protein 652 increases expression ISO gadodiamide results in increased expression of ZNF652 mRNA CTD PMID:20959327 NCBI chr10:80,626,555...80,706,397
Ensembl chr10:80,649,400...80,698,674 		JBrowse link
lisinopril dihydrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme decreases activity ISO Lisinopril analog results in decreased activity of ACE protein CTD PMID:22200082 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131 		JBrowse link
G Ace2 angiotensin I converting enzyme 2 increases expression
multiple interactions
increases activity		 EXP
ISO		 Lisinopril results in increased expression of ACE2 mRNA
ACE2 protein affects the reaction [[[Lisinopril co-treated with Thiorphan co-treated with N-benzyloxycarbonylprolylprolinal] affects the metabolism of AGT protein] which results in decreased abundance of angiotensin I (1-7)]
Lisinopril results in increased activity of ACE2 protein		 CTD PMID:15897343 PMID:16221218 PMID:27649628 NCBI chr  X:30,293,597...30,340,961
Ensembl chr  X:30,293,589...30,340,977 		JBrowse link
G Ache acetylcholinesterase multiple interactions ISO
EXP		 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [Lisinopril inhibits the reaction [Streptozocin results in increased activity of ACHE protein]]; Lisinopril inhibits the reaction [Streptozocin results in increased activity of ACHE protein]
Lisinopril inhibits the reaction [Sodium Fluoride results in decreased activity of ACHE protein]		 CTD PMID:23060470 PMID:31710167 NCBI chr12:19,407,359...19,413,713
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
G Agt angiotensinogen decreases expression
multiple interactions
affects metabolic processing
decreases secretion
increases secretion
affects response to substance
increases expression		 ISO
EXP		 Lisinopril results in decreased expression of AGT protein
[[Lisinopril co-treated with Thiorphan co-treated with N-benzyloxycarbonylprolylprolinal] affects the metabolism of AGT protein] which results in decreased abundance of angiotensin I (1-7); [[Lisinopril co-treated with Thiorphan] affects the metabolism of AGT protein] which results in decreased abundance of angiotensin I (1-7); [Lisinopril affects the metabolism of AGT protein] which results in decreased abundance of Angiotensin II; [Lisinopril affects the metabolism of AGT protein] which results in increased abundance of angiotensin I (1-7); [Lisinopril co-treated with Thiorphan co-treated with N-benzyloxycarbonylprolylprolinal] affects the metabolism of AGT protein; [Lisinopril co-treated with Thiorphan] affects the metabolism of AGT protein; ACE2 protein affects the reaction [[[Lisinopril co-treated with Thiorphan co-treated with N-benzyloxycarbonylprolylprolinal] affects the metabolism of AGT protein] which results in decreased abundance of angiotensin I (1-7)]; Thiorphan inhibits the reaction [[Lisinopril affects the metabolism of AGT protein] which results in increased abundance of angiotensin I (1-7)]
[[Lisinopril co-treated with chymostatin] affects the metabolism of AGT protein] which results in decreased abundance of Angiotensin II; [[Lisinopril co-treated with Thiorphan co-treated with N-benzyloxycarbonylprolylprolinal] affects the metabolism of AGT protein] which results in decreased abundance of angiotensin I (1-7); [[Lisinopril co-treated with Thiorphan] affects the metabolism of AGT protein] which results in decreased abundance of angiotensin I (1-7); [Lisinopril affects the metabolism of AGT protein] which results in decreased abundance of Angiotensin II; [Lisinopril co-treated with chymostatin] affects the metabolism of AGT protein; [Lisinopril co-treated with Thiorphan co-treated with N-benzyloxycarbonylprolylprolinal] affects the metabolism of AGT protein; [Lisinopril co-treated with Thiorphan] affects the metabolism of AGT protein
[Lisinopril co-treated with Losartan] results in increased expression of AGT mRNA
Lisinopril results in decreased secretion of AGT protein
Lisinopril results in increased secretion of AGT protein alternative form
AGT gene alternative form affects the susceptibility to Lisinopril
Lisinopril results in increased expression of AGT mRNA		 CTD PMID:8393685 PMID:8915971 PMID:15897343 PMID:16221218 PMID:16685205 More... NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO Lisinopril results in decreased expression of BCL2 CTD PMID:10075388 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Cd2ap CD2-associated protein multiple interactions EXP Lisinopril inhibits the reaction [Doxorubicin results in increased expression of CD2AP protein] CTD PMID:16636307 NCBI chr 9:18,086,744...18,182,744
Ensembl chr 9:18,086,984...18,182,199 		JBrowse link
G Edn1 endothelin 1 decreases secretion ISO Lisinopril results in decreased secretion of EDN1 protein CTD PMID:19079593 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Gh1 growth hormone 1 multiple interactions EXP [Lisinopril co-treated with GH1 protein] inhibits the reaction [Doxorubicin results in decreased expression of TIMP1 protein]; [Lisinopril co-treated with GH1 protein] inhibits the reaction [Doxorubicin results in increased expression of MMP2 protein]; [Lisinopril co-treated with GH1 protein] inhibits the reaction [Doxorubicin results in increased expression of NOS2 mRNA] CTD PMID:20051877 NCBI chr10:91,228,102...91,230,079
Ensembl chr10:91,228,103...91,230,078 		JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 multiple interactions EXP Lisinopril inhibits the reaction [Doxorubicin results in increased expression of HAVCR1 mRNA]; Lisinopril inhibits the reaction [Doxorubicin results in increased expression of HAVCR1 protein] CTD PMID:19225054 NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698 		JBrowse link
G Hpse heparanase multiple interactions EXP [Spironolactone co-treated with Lisinopril] inhibits the reaction [Doxorubicin results in increased expression of HPSE protein]; Lisinopril inhibits the reaction [Doxorubicin results in increased expression of HPSE protein] CTD PMID:19429930 NCBI chr14:8,896,593...8,937,011
Ensembl chr14:8,896,593...8,937,010 		JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 increases expression ISO Lisinopril results in increased expression of IGFBP1 protein CTD PMID:9663927 NCBI chr14:82,047,415...82,052,482
Ensembl chr14:82,047,415...82,052,482 		JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions EXP [Lisinopril co-treated with GH1 protein] inhibits the reaction [Doxorubicin results in increased expression of MMP2 protein]; Lisinopril inhibits the reaction [Doxorubicin results in increased expression of MMP2 protein] CTD PMID:20051877 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Mpo myeloperoxidase multiple interactions ISO 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [Lisinopril inhibits the reaction [Streptozocin results in increased activity of MPO protein]]; Lisinopril inhibits the reaction [Streptozocin results in increased activity of MPO protein] CTD PMID:23060470 NCBI chr10:72,594,458...72,608,862
Ensembl chr10:72,594,661...72,604,819 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions EXP [Lisinopril co-treated with GH1 protein] inhibits the reaction [Doxorubicin results in increased expression of NOS2 mRNA]; Lisinopril inhibits the reaction [Doxorubicin results in increased expression of NOS2 mRNA] CTD PMID:20051877 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Nphs1 NPHS1 adhesion molecule, nephrin multiple interactions EXP Lisinopril inhibits the reaction [Doxorubicin results in decreased phosphorylation of NPHS1 protein]; Lisinopril inhibits the reaction [Doxorubicin results in increased expression of NPHS1 protein] CTD PMID:16636307 PMID:19293598 NCBI chr 1:85,720,812...85,749,079
Ensembl chr 1:85,720,812...85,749,078 		JBrowse link
G Nphs2 NPHS2 stomatin family member, podocin multiple interactions EXP Lisinopril affects the reaction [Doxorubicin results in increased expression of NPHS2 mRNA]; Lisinopril affects the reaction [Doxorubicin results in increased expression of NPHS2 protein] CTD PMID:16636307 NCBI chr13:68,448,720...68,461,312
Ensembl chr13:68,448,926...68,461,313 		JBrowse link
G Nppa natriuretic peptide A decreases expression ISO Lisinopril results in decreased expression of NPPA protein CTD PMID:8393685 NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351 		JBrowse link
G Ren renin increases expression
multiple interactions		 ISO
EXP		 Lisinopril results in increased expression of REN protein
[Lisinopril co-treated with Losartan] results in increased expression of REN mRNA
Lisinopril results in increased expression of REN mRNA		 CTD PMID:2550029 PMID:8915971 PMID:16221218 NCBI chr13:44,796,260...44,807,491
Ensembl chr13:44,796,091...44,807,489 		JBrowse link
G RT1-M3-1 RT1 class Ib, locus M3, gene 1 affects expression ISO Lisinopril affects the expression of HLA-G mRNA CTD PMID:25811541 NCBI chr20:1,323,976...1,328,126
Ensembl chr20:1,287,521...1,328,117 		JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 multiple interactions EXP [Lisinopril co-treated with GH1 protein] inhibits the reaction [Doxorubicin results in decreased expression of TIMP1 protein]; Lisinopril inhibits the reaction [Doxorubicin results in decreased expression of TIMP1 protein] CTD PMID:20051877 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664 		JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions EXP Lisinopril inhibits the reaction [Doxorubicin results in decreased expression of VEGFA protein] CTD PMID:19293598 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
magnesium dihydroxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp1 caspase 1 multiple interactions ISO [Aluminum Hydroxide co-treated with Magnesium Hydroxide] promotes the reaction [N-t-butyl-n'-tetradecyl-3-tetradecylaminopropionamidine results in increased activity of CASP1 protein]; [Aluminum Hydroxide co-treated with Magnesium Hydroxide] promotes the reaction [N-t-butyl-n'-tetradecyl-3-tetradecylaminopropionamidine results in increased expression of and results in increased secretion of CASP1 protein modified form]; CASP1 protein affects the reaction [[Lipopolysaccharides co-treated with [Aluminum Hydroxide co-treated with Magnesium Hydroxide]] results in increased cleavage of and results in increased secretion of IL1B protein] CTD PMID:18604214 PMID:22075093 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383 		JBrowse link
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit multiple interactions ISO Magnesium Hydroxide inhibits the reaction [Acetylcholine results in increased activity of [CHRNA4 protein co-treated with CHRNB2 protein]] CTD PMID:22750351 NCBI chr 3:168,136,246...168,157,839
Ensembl chr 3:168,136,266...168,156,957 		JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit multiple interactions ISO Magnesium Hydroxide inhibits the reaction [Acetylcholine results in increased activity of [CHRNA4 protein co-treated with CHRNB2 protein]] CTD PMID:22750351 NCBI chr 2:175,181,402...175,189,619
Ensembl chr 2:175,181,402...175,189,619 		JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 multiple interactions ISO [Aluminum Hydroxide co-treated with Magnesium Hydroxide] inhibits the reaction [K-12 lipopolysaccharide results in increased secretion of CXCL10 protein] CTD PMID:17404311 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975 		JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO [[Aluminum Hydroxide co-treated with Magnesium Hydroxide] co-treated with K-12 lipopolysaccharide] results in increased secretion of IL1B protein modified form; [Aluminum Hydroxide co-treated with Magnesium Hydroxide] results in increased secretion of IL1B protein; [Lipopolysaccharides co-treated with [Aluminum Hydroxide co-treated with Magnesium Hydroxide]] results in increased cleavage of and results in increased secretion of IL1B protein; CASP1 protein affects the reaction [[Lipopolysaccharides co-treated with [Aluminum Hydroxide co-treated with Magnesium Hydroxide]] results in increased cleavage of and results in increased secretion of IL1B protein]; N-t-butyl-n'-tetradecyl-3-tetradecylaminopropionamidine promotes the reaction [[Aluminum Hydroxide co-treated with Magnesium Hydroxide] results in increased secretion of IL1B protein]
[[Aluminum Hydroxide co-treated with Magnesium Hydroxide] co-treated with N-t-butyl-n'-tetradecyl-3-tetradecylaminopropionamidine] results in increased secretion of IL1B protein; [Lipopolysaccharides co-treated with [Aluminum Hydroxide co-treated with Magnesium Hydroxide]] results in increased cleavage of and results in increased secretion of IL1B protein; IL1R1 protein affects the reaction [[Lipopolysaccharides co-treated with [Aluminum Hydroxide co-treated with Magnesium Hydroxide]] results in increased cleavage of and results in increased secretion of IL1B protein]; NLRP3 protein affects the reaction [[Lipopolysaccharides co-treated with [Aluminum Hydroxide co-treated with Magnesium Hydroxide]] results in increased cleavage of and results in increased secretion of IL1B protein]; PYCARD protein affects the reaction [[Lipopolysaccharides co-treated with [Aluminum Hydroxide co-treated with Magnesium Hydroxide]] results in increased cleavage of and results in increased secretion of IL1B protein]		 CTD PMID:17404311 PMID:18604214 PMID:22075093 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il1r1 interleukin 1 receptor type 1 multiple interactions ISO IL1R1 protein affects the reaction [[Lipopolysaccharides co-treated with [Aluminum Hydroxide co-treated with Magnesium Hydroxide]] results in increased cleavage of and results in increased secretion of IL1B protein] CTD PMID:18604214 NCBI chr 9:42,504,917...42,580,958
Ensembl chr 9:42,504,735...42,579,937 		JBrowse link
G Il2 interleukin 2 multiple interactions ISO [Aluminum Hydroxide co-treated with Magnesium Hydroxide] results in increased secretion of IL2 protein; N-t-butyl-n'-tetradecyl-3-tetradecylaminopropionamidine promotes the reaction [[Aluminum Hydroxide co-treated with Magnesium Hydroxide] results in increased secretion of IL2 protein]; TLR4 protein affects the reaction [N-t-butyl-n'-tetradecyl-3-tetradecylaminopropionamidine promotes the reaction [[Aluminum Hydroxide co-treated with Magnesium Hydroxide] results in increased secretion of IL2 protein]] CTD PMID:22075093 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566 		JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions ISO NLRP3 protein affects the reaction [[Lipopolysaccharides co-treated with [Aluminum Hydroxide co-treated with Magnesium Hydroxide]] results in increased cleavage of and results in increased secretion of IL1B protein] CTD PMID:18604214 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811 		JBrowse link
G Pycard PYD and CARD domain containing multiple interactions ISO PYCARD protein affects the reaction [[Lipopolysaccharides co-treated with [Aluminum Hydroxide co-treated with Magnesium Hydroxide]] results in increased cleavage of and results in increased secretion of IL1B protein] CTD PMID:18604214 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955 		JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions ISO TLR4 protein affects the reaction [N-t-butyl-n'-tetradecyl-3-tetradecylaminopropionamidine promotes the reaction [[Aluminum Hydroxide co-treated with Magnesium Hydroxide] results in increased secretion of IL2 protein]]; TLR4 protein affects the susceptibility to [[Aluminum Hydroxide co-treated with Magnesium Hydroxide] co-treated with N-t-butyl-n'-tetradecyl-3-tetradecylaminopropionamidine]; TLR4 protein affects the susceptibility to [Aluminum Hydroxide co-treated with Magnesium Hydroxide] CTD PMID:22075093 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
mosapride citrate dihydrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO mosapride inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268 		JBrowse link
potassium citrate monohydrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nefh neurofilament heavy chain affects expression EXP Potassium Citrate affects the expression of NEFH mRNA CTD PMID:22954530 NCBI chr14:79,830,362...79,840,347
Ensembl chr14:79,830,362...79,840,351 		JBrowse link
potassium hydroxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cfl1 cofilin 1 increases expression ISO potassium hydroxide results in increased expression of CFL1 mRNA; potassium hydroxide results in increased expression of CFL1 protein CTD PMID:21469165 NCBI chr 1:202,796,012...202,801,337
Ensembl chr 1:202,786,627...202,817,587 		JBrowse link
G Hspb1 heat shock protein family B (small) member 1 multiple interactions
increases expression		 ISO potassium hydroxide results in decreased expression of and affects the localization of HSPB1 protein
potassium hydroxide results in increased expression of HSPB1 mRNA		 CTD PMID:21469165 NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743 		JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO potassium hydroxide results in increased expression of and results in increased secretion of IL1A protein CTD PMID:21469165 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Sod1 superoxide dismutase 1 increases expression
decreases expression		 ISO potassium hydroxide results in increased expression of SOD1 mRNA
potassium hydroxide results in decreased expression of SOD1 protein		 CTD PMID:21469165 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
royal jelly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO royal jelly inhibits the reaction [Nicotine results in decreased expression of BCL2 mRNA] CTD PMID:30896085 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Casp3 caspase 3 multiple interactions ISO royal jelly inhibits the reaction [Nicotine results in increased expression of CASP3 mRNA] CTD PMID:30896085 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Cat catalase multiple interactions EXP
ISO		 royal jelly inhibits the reaction [Cisplatin results in decreased activity of CAT protein]
royal jelly inhibits the reaction [Nicotine results in decreased activity of CAT protein]		 CTD PMID:20369241 PMID:30896085 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Esr1 estrogen receptor 1 multiple interactions
increases activity
affects binding		 ISO Estradiol inhibits the reaction [royal jelly binds to ESR1 protein]; royal jelly binds to and results in increased activity of ESR1 protein; royal jelly inhibits the reaction [Estradiol binds to ESR1 protein]
royal jelly results in increased activity of ESR1 protein		 CTD PMID:15946813 PMID:17287592 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Esr2 estrogen receptor 2 multiple interactions
affects binding		 ISO Estradiol inhibits the reaction [royal jelly binds to ESR2 protein]; royal jelly binds to and results in increased activity of ESR2 protein; royal jelly inhibits the reaction [Estradiol binds to ESR2 protein] CTD PMID:15946813 PMID:17287592 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919 		JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions ISO royal jelly inhibits the reaction [Nicotine results in decreased expression of PCNA protein] CTD PMID:30896085 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995 		JBrowse link
G Tff1 trefoil factor 1 increases expression ISO royal jelly results in increased expression of TFF1 mRNA CTD PMID:15946813 NCBI chr20:9,235,736...9,239,597
Ensembl chr20:9,235,736...9,239,597 		JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO royal jelly inhibits the reaction [Nicotine results in increased expression of TRP53 mRNA] CTD PMID:30896085 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Vegfa vascular endothelial growth factor A increases expression ISO
EXP		 royal jelly results in increased expression of VEGFA mRNA CTD PMID:15946813 PMID:17287592 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
sodium acetate trihydrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase multiple interactions EXP Sodium Acetate inhibits the reaction [Nicotine results in increased activity of ADA protein] CTD PMID:31857090 NCBI chr 3:152,398,745...152,422,854
Ensembl chr 3:152,398,747...152,447,088 		JBrowse link
G Apob apolipoprotein B multiple interactions ISO [Sodium Acetate co-treated with acetic anhydride] results in increased acetylation of APOB protein CTD PMID:11304478 NCBI chr 6:30,844,386...30,883,983
Ensembl chr 6:30,844,368...30,892,497 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO Sodium Acetate promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]
Sodium Acetate promotes the reaction [biochanin A results in increased expression of CYP1A1 mRNA]; Sodium Acetate promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]		 CTD PMID:31621310 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions ISO Sodium Acetate promotes the reaction [biochanin A results in increased expression of CYP1B1 mRNA]; Sodium Acetate promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] CTD PMID:31621310 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917 		JBrowse link
G Ggt1 gamma-glutamyltransferase 1 multiple interactions EXP Sodium Acetate inhibits the reaction [Nicotine results in increased activity of GGT1 protein] CTD PMID:31857090 NCBI chr20:13,074,695...13,104,095
Ensembl chr20:13,074,700...13,108,442 		JBrowse link
G Il2 interleukin 2 multiple interactions ISO Sodium Acetate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of IL2 protein] CTD PMID:17615583 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566 		JBrowse link
G Kpnb1 karyopherin subunit beta 1 multiple interactions ISO Sodium Acetate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] promotes the reaction [NFATC2 protein binds to KPNB1 protein]] CTD PMID:17615583 NCBI chr10:82,145,662...82,174,437
Ensembl chr10:82,145,420...82,174,605 		JBrowse link
G Nfatc2 nuclear factor of activated T-cells 2 multiple interactions ISO Sodium Acetate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] affects the localization of NFATC2 protein]; Sodium Acetate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] promotes the reaction [NFATC2 protein binds to KPNB1 protein]]; Sodium Acetate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of NFATC2 protein] CTD PMID:17615583 NCBI chr 3:157,195,970...157,328,640
Ensembl chr 3:157,198,872...157,328,325 		JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 multiple interactions ISO Sodium Acetate promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of UGT1A1 mRNA] CTD PMID:31621310 NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Xdh xanthine dehydrogenase multiple interactions EXP Sodium Acetate inhibits the reaction [Nicotine results in increased activity of XDH protein] CTD PMID:31857090 NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268 		JBrowse link
sodium hydroxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Egfr epidermal growth factor receptor affects response to substance ISO EGFR SNP affects the susceptibility to Sodium Hydroxide CTD PMID:27206134 NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Ezr ezrin increases expression ISO Sodium Hydroxide results in increased expression of EZR mRNA CTD PMID:29893927 NCBI chr 1:46,967,961...47,011,505
Ensembl chr 1:46,967,658...47,011,505 		JBrowse link
G Ier3 immediate early response 3 affects response to substance ISO IER3 SNP affects the susceptibility to Sodium Hydroxide CTD PMID:27258892 NCBI chr20:2,928,378...2,929,582
Ensembl chr20:2,928,378...2,929,583 		JBrowse link
G Il1b interleukin 1 beta increases expression ISO Sodium Hydroxide results in increased expression of IL1B protein CTD PMID:29953848 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il22 interleukin 22 affects response to substance ISO IL22 SNP affects the susceptibility to Sodium Hydroxide CTD PMID:27206134 NCBI chr 7:53,801,206...53,805,673
Ensembl chr 7:53,801,206...53,806,186 		JBrowse link
G Kcnk3 potassium two pore domain channel subfamily K member 3 increases activity
decreases response to substance		 ISO Sodium Hydroxide results in increased activity of KCNK3 protein
KCNK3 protein mutant form results in decreased susceptibility to Sodium Hydroxide		 CTD PMID:30365877 NCBI chr 6:25,761,487...25,799,153
Ensembl chr 6:25,763,228...25,799,153 		JBrowse link
G Plau plasminogen activator, urokinase affects response to substance ISO PLAU SNP affects the susceptibility to Sodium Hydroxide CTD PMID:27206134 NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775 		JBrowse link
G RT1-M3-1 RT1 class Ib, locus M3, gene 1 affects response to substance ISO HLA-G SNP affects the susceptibility to Sodium Hydroxide CTD PMID:27258892 NCBI chr20:1,323,976...1,328,126
Ensembl chr20:1,287,521...1,328,117 		JBrowse link
G Trim10 tripartite motif-containing 10 affects response to substance ISO TRIM10 SNP affects the susceptibility to Sodium Hydroxide CTD PMID:27258892 NCBI chr20:1,689,554...1,698,948
Ensembl chr20:1,689,562...1,698,252 		JBrowse link
G Trim31 tripartite motif-containing 31 affects response to substance ISO TRIM31 SNP affects the susceptibility to Sodium Hydroxide CTD PMID:27258892 NCBI chr20:1,653,165...1,666,494
Ensembl chr20:1,653,165...1,666,494 		JBrowse link
G Trim40 tripartite motif-containing 40 affects response to substance ISO TRIM40 SNP affects the susceptibility to Sodium Hydroxide CTD PMID:27258892 NCBI chr20:1,676,188...1,685,906
Ensembl chr20:1,676,270...1,685,214 		JBrowse link
sodium thiosulfate pentahydrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 multiple interactions EXP sodium thiosulfate inhibits the reaction [Isoproterenol results in increased activity of CASP3 protein] CTD PMID:32865837 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp9 caspase 9 multiple interactions EXP sodium thiosulfate inhibits the reaction [Isoproterenol results in increased activity of CASP9 protein] CTD PMID:32865837 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Mpo myeloperoxidase multiple interactions EXP sodium thiosulfate inhibits the reaction [Isoproterenol results in increased activity of MPO protein] CTD PMID:32865837 NCBI chr10:72,594,458...72,608,862
Ensembl chr10:72,594,661...72,604,819 		JBrowse link
tacrolimus hydrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin increases expression EXP Tacrolimus results in increased expression of A2M mRNA CTD PMID:21865292 NCBI chr 4:154,897,770...154,947,787
Ensembl chr 4:154,897,877...154,947,786 		JBrowse link
G Abca1 ATP binding cassette subfamily A member 1 multiple interactions
increases expression		 ISO
EXP		 [Sirolimus co-treated with Tacrolimus] results in increased expression of ABCA1 protein
Tacrolimus results in increased expression of ABCA1 mRNA		 CTD PMID:17016853 PMID:21865292 NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170 		JBrowse link
G Abcb11 ATP binding cassette subfamily B member 11 decreases activity ISO Tacrolimus results in decreased activity of ABCB11 protein CTD PMID:23956101 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730 		JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A affects export
decreases activity
multiple interactions
increases response to substance
increases export
affects response to substance		 ISO ABCB1 protein affects the export of Tacrolimus
Tacrolimus results in decreased activity of ABCB1 protein
[Tacrolimus binds to ABCB1 protein] inhibits the reaction [azidoprazosin binds to ABCB1 protein]; [Tacrolimus results in decreased activity of ABCB1 protein] which results in decreased export of Dexamethasone; Verapamil affects the reaction [ABCB1 protein results in increased export of Tacrolimus]
ABCB1 gene SNP results in increased susceptibility to Tacrolimus
ABCB1 protein affects the susceptibility to Tacrolimus		 CTD PMID:1381629 PMID:11920757 PMID:12352921 PMID:15919446 PMID:15964336 More... NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Acaa1b acetyl-Coenzyme A acyltransferase 1B decreases expression ISO Tacrolimus results in decreased expression of ACAA1B mRNA CTD PMID:25270620 NCBI chr 8:118,872,996...118,881,852
Ensembl chr 8:118,872,997...118,881,825 		JBrowse link
G Acadl acyl-CoA dehydrogenase, long chain decreases expression ISO Tacrolimus results in decreased expression of ACADL mRNA CTD PMID:25270620 NCBI chr 9:68,333,981...68,372,149
Ensembl chr 9:68,333,980...68,372,220 		JBrowse link
G Ace2 angiotensin I converting enzyme 2 decreases expression EXP Tacrolimus results in decreased expression of ACE2 mRNA CTD PMID:21865292 NCBI chr  X:30,293,597...30,340,961
Ensembl chr  X:30,293,589...30,340,977 		JBrowse link
G Acp5 acid phosphatase 5, tartrate resistant multiple interactions ISO Tacrolimus inhibits the reaction [TNFSF11 protein results in increased expression of ACP5 protein] CTD PMID:15207740 NCBI chr 8:20,663,984...20,670,604
Ensembl chr 8:20,663,985...20,667,929 		JBrowse link
G Acta2 actin alpha 2, smooth muscle increases expression ISO Tacrolimus results in increased expression of ACTA2 protein CTD PMID:29362864 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554 		JBrowse link
G Acvr1b activin A receptor type 1B multiple interactions ISO [Tacrolimus inhibits the reaction [FKBP1A protein binds to ACVR1B protein]] which results in decreased ubiquitination of ACVR1B protein; Tacrolimus inhibits the reaction [FKBP1A protein binds to and results in decreased activity of ACVR1B protein]; Tacrolimus inhibits the reaction [FKBP1A protein promotes the reaction [SMURF1 protein binds to SMAD7 protein binds to ACVR1B protein]] CTD PMID:16720724 NCBI chr 7:132,286,266...132,329,679
Ensembl chr 7:132,286,275...132,329,673 		JBrowse link
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 increases expression EXP Tacrolimus results in increased expression of ADAMTS1 mRNA CTD PMID:21865292 NCBI chr11:24,932,227...24,941,068
Ensembl chr11:24,931,761...24,941,103 		JBrowse link
G Adamts2 ADAM metallopeptidase with thrombospondin type 1 motif, 2 increases expression ISO Tacrolimus results in increased expression of ADAMTS2 mRNA CTD PMID:29362864 NCBI chr10:34,920,996...35,126,465
Ensembl chr10:34,921,049...35,123,821 		JBrowse link
G Adcy9 adenylate cyclase 9 multiple interactions ISO Tacrolimus inhibits the reaction [Calcium inhibits the reaction [Miconazole results in increased activity of ADCY9 protein]] CTD PMID:30607468 NCBI chr10:11,138,966...11,262,067
Ensembl chr10:11,139,446...11,262,066 		JBrowse link
G Adra1d adrenoceptor alpha 1D increases expression EXP Tacrolimus results in increased expression of ADRA1D mRNA CTD PMID:21865292 NCBI chr 3:118,793,356...118,809,354
Ensembl chr 3:118,793,346...118,809,354 		JBrowse link
G Aif1 allograft inflammatory factor 1 increases expression ISO Tacrolimus results in increased expression of AIF1 mRNA CTD PMID:29362864 NCBI chr20:3,646,784...3,652,670
Ensembl chr20:3,646,777...3,652,668 		JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 decreases expression ISO Tacrolimus results in decreased expression of ALDH1A1 mRNA CTD PMID:25270620 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961 		JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member decreases expression ISO Tacrolimus results in decreased expression of ALDH2 mRNA CTD PMID:25270620 NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521 		JBrowse link
G Aldh9a1 aldehyde dehydrogenase 9 family, member A1 decreases expression ISO Tacrolimus results in decreased expression of ALDH9A1 mRNA CTD PMID:25270620 NCBI chr13:79,505,738...79,522,539
Ensembl chr13:79,505,695...79,540,568 		JBrowse link
G Alg3 ALG3, alpha-1,3- mannosyltransferase decreases expression ISO Tacrolimus results in decreased expression of ALG3 mRNA CTD PMID:25270620 NCBI chr11:80,300,487...80,306,014
Ensembl chr11:80,300,498...80,307,912 		JBrowse link
G Angptl6 angiopoietin-like 6 increases expression EXP Tacrolimus results in increased expression of ANGPTL6 mRNA CTD PMID:21865292 NCBI chr 8:19,413,617...19,419,925
Ensembl chr 8:19,413,619...19,419,925 		JBrowse link
G Ankrd1 ankyrin repeat domain 1 increases expression ISO Tacrolimus results in increased expression of ANKRD1 mRNA CTD PMID:29362864 NCBI chr 1:233,815,851...233,834,891
Ensembl chr 1:233,815,851...233,834,919 		JBrowse link
G Ankrd34a ankyrin repeat domain 34A decreases expression ISO Tacrolimus results in decreased expression of ANKRD34A mRNA CTD PMID:25270620 NCBI chr 2:184,129,830...184,135,075
Ensembl chr 2:184,129,238...184,135,116 		JBrowse link
G Anos1 anosmin 1 increases expression ISO Tacrolimus results in increased expression of WFDC17 mRNA CTD PMID:29362864 NCBI chr10:68,561,954...68,562,801
Ensembl chr10:68,561,954...68,562,801 		JBrowse link
G Anpep alanyl aminopeptidase, membrane increases secretion EXP Tacrolimus results in increased secretion of ANPEP protein CTD PMID:7514309 NCBI chr 1:133,767,332...133,810,137
Ensembl chr 1:133,767,332...133,785,789 		JBrowse link
G Anxa1 annexin A1 increases expression EXP Tacrolimus results in increased expression of ANXA1 CTD PMID:20484890 NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343 		JBrowse link
G Aoc1 amine oxidase, copper containing 1 increases expression ISO Tacrolimus results in increased expression of AOC1 mRNA CTD PMID:29362864 NCBI chr 4:77,812,260...77,831,846
Ensembl chr 4:77,812,260...77,831,840 		JBrowse link
G Areg amphiregulin increases expression EXP Tacrolimus results in increased expression of AREG mRNA CTD PMID:21865292 NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535 		JBrowse link
G Arfrp1 ADP-ribosylation factor related protein 1 increases expression ISO Tacrolimus results in increased expression of ARFRP1 mRNA CTD PMID:25270620 NCBI chr 3:168,466,351...168,473,960
Ensembl chr 3:168,466,496...168,473,914 		JBrowse link
G Arhgap45 Rho GTPase activating protein 45 increases expression ISO Tacrolimus results in increased expression of ARHGAP45 mRNA CTD PMID:21621594 NCBI chr 7:9,674,873...9,690,286
Ensembl chr 7:9,674,897...9,690,268 		JBrowse link
G Arhgef11 Rho guanine nucleotide exchange factor 11 increases expression ISO Tacrolimus results in increased expression of ARHGEF11 mRNA CTD PMID:29380240 NCBI chr 2:173,074,383...173,195,962
Ensembl chr 2:173,074,368...173,196,010 		JBrowse link
G Arpc5 actin related protein 2/3 complex, subunit 5 increases expression ISO Tacrolimus results in increased expression of ARPC5 mRNA CTD PMID:29380240 NCBI chr13:64,904,504...64,913,413
Ensembl chr13:64,887,136...64,913,410 		JBrowse link
G Arv1 ARV1 homolog, fatty acid homeostasis modulator increases expression ISO Tacrolimus results in increased expression of ARV1 mRNA CTD PMID:25270620 NCBI chr19:52,692,337...52,704,156
Ensembl chr19:52,692,337...52,704,156 		JBrowse link
G Asxl3 ASXL transcriptional regulator 3 decreases expression ISO Tacrolimus results in decreased expression of ASXL3 mRNA CTD PMID:29362864 NCBI chr18:13,593,529...13,766,324
Ensembl chr18:13,593,985...13,762,427 		JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO Tacrolimus results in increased expression of ATF3 mRNA CTD PMID:23958496 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631 		JBrowse link
G Atf4 activating transcription factor 4 increases expression ISO Tacrolimus results in increased expression of ATF4 mRNA CTD PMID:23958496 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446 		JBrowse link
G Atf6 activating transcription factor 6 increases expression ISO Tacrolimus results in increased expression of ATF6 mRNA CTD PMID:23958496 NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177 		JBrowse link
G Atp1b1 ATPase Na+/K+ transporting subunit beta 1 decreases expression ISO Tacrolimus results in decreased expression of ATP1B1 mRNA CTD PMID:25270620 NCBI chr13:76,786,580...76,807,096
Ensembl chr13:76,786,578...76,807,459 		JBrowse link
G Atp1b3 ATPase Na+/K+ transporting subunit beta 3 decreases expression ISO Tacrolimus results in decreased expression of ATP1B3 mRNA CTD PMID:25270620 NCBI chr 8:96,910,265...96,941,592
Ensembl chr 8:96,910,309...96,941,598 		JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 increases expression ISO Tacrolimus results in increased expression of ATP2A2 mRNA CTD PMID:25270620 NCBI chr12:34,072,710...34,122,142
Ensembl chr12:34,072,683...34,122,101 		JBrowse link
G B2m beta-2 microglobulin increases expression ISO Tacrolimus results in increased expression of B2M mRNA CTD PMID:29362864 NCBI chr 3:109,095,740...109,101,764
Ensembl chr 3:109,095,729...109,101,766 		JBrowse link
G Bad BCL2-associated agonist of cell death multiple interactions EXP
ISO		 Tacrolimus inhibits the reaction [Ammonium Chloride results in decreased phosphorylation of BAD protein]
Tacrolimus inhibits the reaction [Rotenone results in decreased phosphorylation of BAD protein]		 CTD PMID:15036616 PMID:15280438 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823 		JBrowse link
G Batf3 basic leucine zipper ATF-like transcription factor 3 increases expression ISO Tacrolimus results in increased expression of BATF3 mRNA CTD PMID:29362864 NCBI chr13:102,689,657...102,701,241
Ensembl chr13:102,689,657...102,701,139 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
increases expression		 ISO
EXP		 Tacrolimus inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of BAX protein]
Tacrolimus results in increased expression of BAX protein
[Tacrolimus co-treated with 3-nitropropionic acid] affects the localization of BAX protein		 CTD PMID:10205001 PMID:15571979 PMID:27606422 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases expression
increases expression		 ISO
EXP		 Tacrolimus inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in decreased expression of BCL2 protein]
Tacrolimus results in decreased expression of BCL2 protein
[Tacrolimus co-treated with 3-nitropropionic acid] affects the localization of BCL2 protein
Tacrolimus results in increased expression of BCL2 protein		 CTD PMID:10205001 PMID:15571979 PMID:27606422 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions ISO Tacrolimus inhibits the reaction [Superantigens results in increased expression of BCL2L1 protein] CTD PMID:10532544 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479 		JBrowse link
G Bcl3 BCL3, transcription coactivator increases expression ISO Tacrolimus results in increased expression of BCL3 mRNA CTD PMID:23958496 NCBI chr 1:79,471,368...79,485,908
Ensembl chr 1:79,471,369...79,485,607 		JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions EXP Tacrolimus inhibits the reaction [decamethrin results in increased expression of BDNF exon]; Tacrolimus promotes the reaction [U 0126 inhibits the reaction [decamethrin results in increased expression of BDNF exon]]; U 0126 promotes the reaction [Tacrolimus inhibits the reaction [decamethrin results in increased expression of BDNF exon]] CTD PMID:22079160 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 increases expression EXP Tacrolimus results in increased expression of BIRC3 mRNA CTD PMID:21865292 NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases expression ISO Tacrolimus results in decreased expression of BIRC5 mRNA CTD PMID:16574167 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380 		JBrowse link
G Bmp7 bone morphogenetic protein 7 multiple interactions
decreases expression		 EXP Ramipril inhibits the reaction [Tacrolimus results in decreased expression of BMP7 protein]; valsartan inhibits the reaction [Tacrolimus results in decreased expression of BMP7 protein] CTD PMID:17703430 NCBI chr 3:161,639,915...161,716,938
Ensembl chr 3:161,516,462...161,716,788 		JBrowse link
G Btg2 BTG anti-proliferation factor 2 increases expression EXP Tacrolimus results in increased expression of BTG2 mRNA CTD PMID:21865292 NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628 		JBrowse link
G Btnl9 butyrophilin-like 9 decreases expression ISO Tacrolimus results in decreased expression of BTNL9 mRNA CTD PMID:29362864 NCBI chr10:33,466,059...33,489,229
Ensembl chr10:33,470,536...33,489,025 		JBrowse link
G C1qa complement C1q A chain increases expression ISO Tacrolimus results in increased expression of C1QA mRNA CTD PMID:29362864 NCBI chr 5:149,133,635...149,136,482
Ensembl chr 5:149,133,636...149,136,534 		JBrowse link
G C1qb complement C1q B chain increases expression ISO Tacrolimus results in increased expression of C1QB mRNA CTD PMID:29362864 NCBI chr 5:149,118,843...149,124,394
Ensembl chr 5:149,118,846...149,124,407 		JBrowse link
G C1qc complement C1q C chain increases expression ISO Tacrolimus results in increased expression of C1QC mRNA CTD PMID:29362864 NCBI chr 5:149,127,424...149,130,732
Ensembl chr 5:149,127,415...149,131,017 		JBrowse link
G C2 complement C2 increases expression EXP Tacrolimus results in increased expression of C2 mRNA CTD PMID:21865292 NCBI chr20:3,951,474...3,970,376
Ensembl chr20:3,951,474...3,976,505 		JBrowse link
G C3 complement C3 increases expression EXP
ISO		 Tacrolimus results in increased expression of C3 mRNA CTD PMID:21865292 PMID:29362864 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429 		JBrowse link
G C4b complement C4B (Chido blood group) increases expression EXP Tacrolimus results in increased expression of C4B mRNA CTD PMID:21865292 NCBI chr20:4,197,371...4,211,684
Ensembl chr20:4,197,366...4,211,681 		JBrowse link
G Calb1 calbindin 1 decreases expression EXP Tacrolimus results in decreased expression of CALB1 mRNA; Tacrolimus results in decreased expression of CALB1 protein CTD PMID:14978156 PMID:21865292 NCBI chr 5:29,375,624...29,402,532
Ensembl chr 5:29,375,642...29,402,431 		JBrowse link
G Calcr calcitonin receptor multiple interactions ISO Tacrolimus inhibits the reaction [TNFSF11 protein results in increased expression of CALCR mRNA] CTD PMID:21869564 NCBI chr 4:31,661,270...31,736,392
Ensembl chr 4:31,661,273...31,736,392 		JBrowse link
G Calr calreticulin increases expression ISO Tacrolimus results in increased expression of CALR mRNA CTD PMID:25270620 NCBI chr19:23,308,525...23,313,420
Ensembl chr19:23,308,351...23,313,414 		JBrowse link
G Camk1d calcium/calmodulin-dependent protein kinase ID increases expression ISO Tacrolimus results in increased expression of CAMK1D mRNA CTD PMID:23958496 NCBI chr17:72,581,899...72,982,704
Ensembl chr17:72,581,979...72,980,556 		JBrowse link
G Capg capping actin protein, gelsolin like increases expression EXP Tacrolimus results in increased expression of CAPG mRNA CTD PMID:21865292 NCBI chr 4:104,594,743...104,611,856
Ensembl chr 4:104,594,753...104,611,856 		JBrowse link
G Casp3 caspase 3 multiple interactions
increases cleavage
increases activity		 ISO
EXP		 Tacrolimus inhibits the reaction [FAS protein results in increased activity of CASP3 protein]; Tacrolimus inhibits the reaction [Thapsigargin results in increased activity of CASP3 protein]
Tacrolimus results in increased cleavage of CASP3 protein
Tacrolimus results in increased activity of CASP3 protein
MK0626 inhibits the reaction [Tacrolimus results in increased activity of CASP3 protein]; NGF protein inhibits the reaction [Tacrolimus results in increased activity of CASP3 protein]; Tacrolimus inhibits the reaction [3-nitropropionic acid results in increased activity of CASP3 protein]; Tacrolimus inhibits the reaction [[Lithium co-treated with Pilocarpine] results in increased activity of CASP3 protein]; Tacrolimus inhibits the reaction [Hydrogen Peroxide results in increased activity of CASP3 protein]; Tacrolimus inhibits the reaction [Oxygen deficiency results in increased activity of CASP3 protein]
Tacrolimus inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased activity of CASP3 protein]; Tacrolimus inhibits the reaction [S-Nitrosoglutathione results in increased activity of CASP3 protein]		 CTD PMID:10205001 PMID:12642403 PMID:12871656 PMID:12892836 PMID:15207740 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp8 caspase 8 multiple interactions
increases expression		 ISO Tacrolimus inhibits the reaction [FAS protein results in increased activity of CASP8 protein]
Tacrolimus results in increased expression of CASP8 protein		 CTD PMID:15548389 PMID:27606422 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Casp9 caspase 9 multiple interactions
increases expression		 ISO Tacrolimus inhibits the reaction [FAS protein results in increased activity of CASP9 protein]
Tacrolimus results in increased expression of CASP9 protein		 CTD PMID:15548389 PMID:27606422 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Cat catalase increases expression
decreases response to substance		 EXP
ISO		 Tacrolimus results in increased expression of CAT protein
CAT protein results in decreased susceptibility to Tacrolimus		 CTD PMID:14675044 PMID:18766458 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Cbll1 Cbl proto-oncogene like 1 increases expression ISO Tacrolimus results in increased expression of CBLL1 mRNA CTD PMID:21621594 NCBI chr 6:48,071,190...48,086,174
Ensembl chr 6:48,071,190...48,086,444 		JBrowse link
G Ccdc88b coiled-coil domain containing 88B increases expression ISO Tacrolimus results in increased expression of CCDC88B mRNA CTD PMID:29362864 NCBI chr 1:204,036,913...204,052,878
Ensembl chr 1:204,036,918...204,052,970 		JBrowse link
G Ccl11 C-C motif chemokine ligand 11 decreases expression ISO Tacrolimus results in decreased expression of CCL11 mRNA CTD PMID:15948978 NCBI chr10:67,028,328...67,032,929
Ensembl chr10:67,028,328...67,032,926 		JBrowse link
G Ccl17 C-C motif chemokine ligand 17 increases expression ISO Tacrolimus results in increased expression of CCL17 mRNA CTD PMID:29362864 NCBI chr19:10,202,317...10,203,768
Ensembl chr19:10,202,128...10,203,819 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions
increases expression		 EXP
ISO		 pyrrolidine dithiocarbamic acid inhibits the reaction [Tacrolimus results in increased expression of CCL2 mRNA]
7-oxozeanol inhibits the reaction [Tacrolimus results in increased expression of CCL2 mRNA]; 7-oxozeanol inhibits the reaction [Tacrolimus results in increased expression of CCL2 protein]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [Tacrolimus results in increased expression of CCL2 mRNA]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [Tacrolimus results in increased expression of CCL2 protein]; ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate inhibits the reaction [Tacrolimus results in increased expression of CCL2 mRNA]; parthenolide inhibits the reaction [Tacrolimus results in increased expression of CCL2 mRNA]; pyrazolanthrone inhibits the reaction [Tacrolimus results in increased expression of CCL2 mRNA]; pyrazolanthrone inhibits the reaction [Tacrolimus results in increased expression of CCL2 protein]; salubrinal inhibits the reaction [Tacrolimus results in increased expression of CCL2 mRNA]; sulforaphane inhibits the reaction [Tacrolimus results in increased expression of CCL2 mRNA]		 CTD PMID:12472797 PMID:23958496 PMID:29362864 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccl20 C-C motif chemokine ligand 20 increases expression ISO Tacrolimus results in increased expression of CCL20 mRNA CTD PMID:23958496 NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 decreases expression
increases expression
multiple interactions		 ISO Tacrolimus results in decreased expression of CCL5 mRNA
Tacrolimus results in increased expression of CCL5 mRNA
7-oxozeanol inhibits the reaction [Tacrolimus results in increased expression of CCL5 mRNA]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [Tacrolimus results in increased expression of CCL5 mRNA]; ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate inhibits the reaction [Tacrolimus results in increased expression of CCL5 mRNA]; parthenolide inhibits the reaction [Tacrolimus results in increased expression of CCL5 mRNA]; pyrazolanthrone inhibits the reaction [Tacrolimus results in increased expression of CCL5 mRNA]; salubrinal inhibits the reaction [Tacrolimus results in increased expression of CCL5 mRNA]; sulforaphane inhibits the reaction [Tacrolimus results in increased expression of CCL5 mRNA]		 CTD PMID:15948978 PMID:23958496 PMID:25270620 NCBI chr10:68,322,826...68,327,365
Ensembl chr10:68,322,829...68,327,377 		JBrowse link
G Ccl6 C-C motif chemokine ligand 6 increases expression EXP
ISO		 Tacrolimus results in increased expression of CCL6 mRNA CTD PMID:21865292 PMID:29362864 NCBI chr10:68,381,179...68,385,811
Ensembl chr10:68,380,188...68,384,001 		JBrowse link
G Ccl7 C-C motif chemokine ligand 7 increases expression ISO Tacrolimus results in increased expression of CCL7 mRNA CTD PMID:23958496 PMID:29362864 NCBI chr10:67,016,446...67,018,296
Ensembl chr10:67,016,446...67,018,303 		JBrowse link
G Ccn2 cellular communication network factor 2 multiple interactions EXP Tacrolimus inhibits the reaction [Paraquat results in increased expression of CCN2 mRNA]; Tacrolimus inhibits the reaction [Paraquat results in increased secretion of CCN2 protein] CTD PMID:33000210 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734 		JBrowse link
G Ccna2 cyclin A2 increases expression ISO Tacrolimus results in increased expression of CCNA2 mRNA CTD PMID:29362864 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577 		JBrowse link
G Ccnb2 cyclin B2 decreases expression
increases expression		 ISO Tacrolimus results in decreased expression of CCNB2 mRNA
Tacrolimus results in increased expression of CCNB2 mRNA		 CTD PMID:16574167 PMID:29362864 NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874 		JBrowse link
G Ccr2 C-C motif chemokine receptor 2 increases expression ISO Tacrolimus results in increased expression of CCR2 mRNA CTD PMID:29362864 NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100 		JBrowse link
G Ccr3 C-C motif chemokine receptor 3 decreases expression ISO Tacrolimus results in decreased expression of CCR3 mRNA CTD PMID:15948978 NCBI chr 8:123,586,100...123,634,178
Ensembl chr 8:123,616,236...123,634,990 		JBrowse link
G Ccrl2 C-C motif chemokine receptor like 2 increases expression ISO Tacrolimus results in increased expression of CCRL2 mRNA CTD PMID:23958496 NCBI chr 8:111,034,279...111,036,914
Ensembl chr 8:111,034,279...111,036,664 		JBrowse link
G Cd2 Cd2 molecule multiple interactions ISO Tacrolimus inhibits the reaction [CD2 protein results in increased expression of IL2 protein] CTD PMID:1705513 NCBI chr 2:188,710,895...188,724,044
Ensembl chr 2:188,710,900...188,724,026 		JBrowse link
G Cd44 CD44 molecule (Indian blood group) increases expression EXP Tacrolimus results in increased expression of CD44 mRNA CTD PMID:21865292 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620 		JBrowse link
G Cd68 Cd68 molecule increases expression EXP Tacrolimus results in increased expression of CD68 mRNA CTD PMID:21865292 NCBI chr10:54,381,814...54,383,693
Ensembl chr10:54,381,815...54,383,697 		JBrowse link
G Cd74 CD74 molecule increases expression ISO Tacrolimus results in increased expression of CD74 mRNA CTD PMID:23958496 NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003 		JBrowse link
G Cd80 Cd80 molecule decreases expression ISO Tacrolimus results in decreased expression of CD80 protein CTD PMID:15241357 NCBI chr11:62,254,543...62,293,414
Ensembl chr11:62,254,624...62,292,030 		JBrowse link
G Cd83 CD83 molecule increases expression ISO Tacrolimus results in increased expression of CD83 mRNA CTD PMID:29362864 NCBI chr17:20,887,309...20,907,009
Ensembl chr17:20,887,309...20,907,083 		JBrowse link
G Cd86 CD86 molecule decreases expression ISO Tacrolimus results in decreased expression of CD86 protein CTD PMID:15241357 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818 		JBrowse link
G Cdca3 cell division cycle associated 3 increases expression ISO Tacrolimus results in increased expression of CDCA3 mRNA CTD PMID:29362864 NCBI chr 4:157,634,775...157,638,799
Ensembl chr 4:157,634,928...157,638,799 		JBrowse link
G Cdca5 cell division cycle associated 5 increases expression ISO Tacrolimus results in increased expression of CDCA5 mRNA CTD PMID:29362864 NCBI chr 1:203,378,550...203,392,027
Ensembl chr 1:203,378,577...203,392,023 		JBrowse link
G Cdca8 cell division cycle associated 8 increases expression ISO Tacrolimus results in increased expression of CDCA8 mRNA CTD PMID:29362864 NCBI chr 5:137,176,414...137,198,686
Ensembl chr 5:137,176,417...137,198,629 		JBrowse link
G Cdh1 cadherin 1 decreases expression ISO Tacrolimus results in decreased expression of CDH1 protein CTD PMID:22416070 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775 		JBrowse link
G Cdh11 cadherin 11 increases expression ISO Tacrolimus results in increased expression of CDH11 mRNA CTD PMID:29362864 NCBI chr19:2,148,447...2,305,754
Ensembl chr19:2,148,458...2,304,272 		JBrowse link
G Cdh16 cadherin 16 decreases expression ISO Tacrolimus results in decreased expression of CDH16 mRNA CTD PMID:22416070 NCBI chr19:360,824...371,008
Ensembl chr19:360,824...371,007 		JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases expression EXP Tacrolimus results in increased expression of CDKN1B mRNA CTD PMID:21865292 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982 		JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha increases expression ISO Tacrolimus results in increased expression of CEBPA mRNA CTD PMID:29362864 NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412 		JBrowse link
G Cenpw centromere protein W increases expression ISO Tacrolimus results in increased expression of CENPW mRNA CTD PMID:29362864 NCBI chr 1:27,525,324...27,530,464
Ensembl chr 1:27,525,324...27,530,464 		JBrowse link
G Cfi complement factor I increases expression EXP Tacrolimus results in increased expression of CFI mRNA CTD PMID:21865292 NCBI chr 2:218,389,079...218,430,565
Ensembl chr 2:218,387,990...218,430,561 		JBrowse link
G Ckap2 cytoskeleton associated protein 2 increases expression ISO Tacrolimus results in increased expression of CKAP2 mRNA CTD PMID:29362864 NCBI chr16:69,839,668...69,864,852
Ensembl chr16:69,839,630...69,864,913 		JBrowse link
G Ckap4 cytoskeleton-associated protein 4 increases expression EXP Tacrolimus results in increased expression of CKAP4 mRNA CTD PMID:21865292 NCBI chr 7:19,230,814...19,238,914
Ensembl chr 7:19,230,203...19,238,914 		JBrowse link
G Cldn1 claudin 1 decreases expression ISO Tacrolimus results in decreased expression of CLDN1 mRNA CTD PMID:22416070 NCBI chr11:74,421,569...74,436,728
Ensembl chr11:74,421,569...74,436,724 		JBrowse link
G Cldn4 claudin 4 increases expression EXP Tacrolimus results in increased expression of CLDN4 mRNA CTD PMID:21865292 NCBI chr12:21,751,638...21,753,436
Ensembl chr12:21,751,331...21,753,436 		JBrowse link
G Cldn7 claudin 7 increases expression EXP Tacrolimus results in increased expression of CLDN7 mRNA CTD PMID:21865292 NCBI chr10:54,689,684...54,692,177
Ensembl chr10:54,689,987...54,692,171 		JBrowse link
G Clec7a C-type lectin domain containing 7A increases expression ISO Tacrolimus results in increased expression of CLEC7A mRNA CTD PMID:29362864 NCBI chr 4:162,902,731...162,913,931
Ensembl chr 4:162,902,732...162,913,897 		JBrowse link
G Clk3 CDC-like kinase 3 increases expression ISO Tacrolimus results in increased expression of CLK3 mRNA CTD PMID:25270620 NCBI chr 8:58,152,155...58,167,196
Ensembl chr 8:58,152,155...58,168,181 		JBrowse link
G Clu clusterin increases expression EXP Tacrolimus results in increased expression of CLU mRNA CTD PMID:21865292 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315 		JBrowse link
G Coch cochlin increases expression ISO Tacrolimus results in increased expression of COCH mRNA CTD PMID:25270620 NCBI chr 6:69,031,139...69,045,124
Ensembl chr 6:69,031,167...69,045,109 		JBrowse link
G Col1a1 collagen type I alpha 1 chain increases expression ISO Tacrolimus results in increased expression of COL1A1 mRNA CTD PMID:29362864 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624 		JBrowse link
G Col1a2 collagen type I alpha 2 chain increases expression ISO Tacrolimus results in increased expression of COL1A2 mRNA CTD PMID:29362864 NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867 		JBrowse link
G Col3a1 collagen type III alpha 1 chain increases expression ISO Tacrolimus results in increased expression of COL3A1 mRNA CTD PMID:29362864 NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547 		JBrowse link
G Cops8 COP9 signalosome subunit 8 increases expression ISO Tacrolimus results in increased expression of COPS8 mRNA CTD PMID:25270620 NCBI chr 9:91,207,427...91,217,258
Ensembl chr 9:91,207,395...91,217,258 		JBrowse link
G Cp ceruloplasmin increases expression EXP Tacrolimus results in increased expression of CP mRNA CTD PMID:21865292 NCBI chr 2:102,439,433...102,498,075
Ensembl chr 2:102,439,624...102,498,075 		JBrowse link
G Creb3l3 cAMP responsive element binding protein 3-like 3 decreases expression ISO Tacrolimus results in decreased expression of CREB3L3 mRNA CTD PMID:25270620 NCBI chr 7:8,622,614...8,631,053
Ensembl chr 7:8,622,614...8,631,048 		JBrowse link
G Creld2 cysteine-rich with EGF-like domains 2 increases expression ISO Tacrolimus results in increased expression of CRELD2 mRNA CTD PMID:25270620 NCBI chr 7:119,909,626...119,916,556
Ensembl chr 7:119,909,633...119,916,543 		JBrowse link
G Csf1 colony stimulating factor 1 increases expression ISO Tacrolimus results in increased expression of CSF1 mRNA CTD PMID:23958496 NCBI chr 2:195,377,215...195,396,608
Ensembl chr 2:195,377,215...195,411,704 		JBrowse link
G Csf2 colony stimulating factor 2 decreases expression
increases expression
multiple interactions		 ISO Tacrolimus results in decreased expression of CSF2 protein
Tacrolimus results in increased expression of CSF2 mRNA
Sirolimus inhibits the reaction [Tacrolimus inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of CSF2 protein]]; Tacrolimus inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CSF2 protein]		 CTD PMID:1376361 PMID:11407316 PMID:23958496 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199 		JBrowse link
G Csf2rb colony stimulating factor 2 receptor subunit beta increases expression ISO Tacrolimus results in increased expression of CSF2RB2 mRNA CTD PMID:29362864 NCBI chr 7:109,876,919...109,901,589
Ensembl chr 7:109,886,425...109,904,157 		JBrowse link
G Ctsl cathepsin L multiple interactions
increases expression		 ISO
EXP		 Tacrolimus inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CTSL protein]
Tacrolimus results in increased expression of CTSL mRNA		 CTD PMID:18172886 PMID:21865292 PMID:25270620 NCBI chr17:764,370...770,533
Ensembl chr17:764,309...770,548 		JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 increases expression EXP
ISO		 Tacrolimus results in increased expression of CXCL10 mRNA CTD PMID:21865292 PMID:23958496 PMID:25270620 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975 		JBrowse link
G Cxcl11 C-X-C motif chemokine ligand 11 increases expression ISO Tacrolimus results in increased expression of CXCL11 mRNA CTD PMID:23958496 NCBI chr14:15,689,432...15,692,207
Ensembl chr14:15,689,424...15,692,271 		JBrowse link
G Cyba cytochrome b-245 alpha chain multiple interactions
increases expression		 ISO Ramipril inhibits the reaction [Tacrolimus results in increased expression of CYBA mRNA] CTD PMID:12352326 NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721 		JBrowse link
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 increases expression EXP Tacrolimus results in increased expression of CYP27B1 mRNA CTD PMID:21865292 NCBI chr 7:62,869,340...62,876,242
Ensembl chr 7:62,871,297...62,876,241 		JBrowse link
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 multiple interactions ISO CYP2C19 affects the reaction [Lansoprazole affects the susceptibility to Tacrolimus]; CYP2C19 affects the susceptibility to [Tacrolimus co-treated with Lansoprazole]; CYP2C19 affects the susceptibility to [Tacrolimus co-treated with Rabeprazole]; CYP2C19 gene mutant form affects the susceptibility to [Lansoprazole co-treated with Tacrolimus] CTD PMID:15010519 PMID:15285851 PMID:17377957 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases metabolic processing
affects metabolic processing
decreases methylation
multiple interactions		 ISO CYP3A4 protein results in increased metabolism of Tacrolimus
CYP3A4 protein affects the metabolism of Tacrolimus
CYP3A4 protein results in decreased methylation of Tacrolimus
Metronidazole inhibits the reaction [CYP3A4 protein results in increased metabolism of Tacrolimus]		 CTD PMID:15010519 PMID:15855244 PMID:15919446 PMID:15951320 PMID:15964336 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 multiple interactions
decreases methylation
affects metabolic processing
affects response to substance		 ISO CYP3A5 affects the susceptibility to [Tacrolimus co-treated with Lansoprazole]; CYP3A5 affects the susceptibility to [Tacrolimus co-treated with Rabeprazole]; CYP3A5 gene polymorphism affects the reaction [Ketoconazole results in decreased metabolism of Tacrolimus]
CYP3A5 protein results in decreased methylation of Tacrolimus
CYP3A5 gene polymorphism affects the metabolism of Tacrolimus; CYP3A5 gene SNP affects the metabolism of Tacrolimus; CYP3A5 protein affects the metabolism of Tacrolimus; CYP3A5 protein polymorphism affects the metabolism of Tacrolimus
CYP3A5 gene affects the susceptibility to Tacrolimus		 CTD PMID:15502717 PMID:15723604 PMID:15729180 PMID:15808586 PMID:15919447 More... NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422 		JBrowse link
G Dcn decorin increases expression ISO Tacrolimus results in increased expression of DCN mRNA CTD PMID:29362864 NCBI chr 7:32,281,252...32,321,291
Ensembl chr 7:32,281,252...32,321,270 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions
increases expression		 ISO salubrinal promotes the reaction [Tacrolimus results in increased expression of DDIT3 protein]
Tacrolimus results in increased expression of DDIT3 mRNA		 CTD PMID:23958496 PMID:25270620 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201 		JBrowse link
G Ddit4l DNA-damage-inducible transcript 4-like decreases expression EXP Tacrolimus results in decreased expression of DDIT4L mRNA CTD PMID:21865292 NCBI chr 2:226,128,273...226,131,044
Ensembl chr 2:226,128,276...226,131,375 		JBrowse link
G Dhcr24 24-dehydrocholesterol reductase decreases expression ISO Tacrolimus results in decreased expression of DHCR24 mRNA CTD PMID:25270620 NCBI chr 5:121,344,637...121,368,853
Ensembl chr 5:121,344,575...121,371,137 		JBrowse link
G Dnajc30 DnaJ heat shock protein family (Hsp40) member C30 decreases expression ISO Tacrolimus results in decreased expression of DNAJC30 mRNA CTD PMID:25270620 NCBI chr12:21,628,323...21,629,389
Ensembl chr12:21,626,450...21,629,408 		JBrowse link
G Dnm1l dynamin 1-like multiple interactions ISO PINK1 protein affects the reaction [Tacrolimus results in increased phosphorylation of DNM1L protein]
Tacrolimus inhibits the reaction [ferric ammonium citrate results in decreased phosphorylation of DNM1L protein]		 CTD PMID:19492085 PMID:26318285 NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482 		JBrowse link
G Doc2a double C2 domain alpha decreases expression ISO Tacrolimus results in decreased expression of DOC2A mRNA CTD PMID:25270620 NCBI chr 1:181,457,415...181,462,528
Ensembl chr 1:181,458,390...181,462,030 		JBrowse link
G Dock10 dedicator of cytokinesis 10 increases expression ISO Tacrolimus results in increased expression of DOCK10 mRNA CTD PMID:29362864 NCBI chr 9:81,843,599...82,101,540
Ensembl chr 9:81,843,604...82,101,525 		JBrowse link
G Dpp4 dipeptidylpeptidase 4 increases activity
multiple interactions		 EXP Tacrolimus results in increased activity of DPP4 protein
MK0626 inhibits the reaction [Tacrolimus results in increased activity of DPP4 protein]		 CTD PMID:24959755 NCBI chr 3:46,962,243...47,043,870
Ensembl chr 3:46,962,243...47,043,901 		JBrowse link
G Drd2 dopamine receptor D2 affects activity
multiple interactions		 EXP Tacrolimus affects the activity of DRD2 protein
Sulpiride inhibits the reaction [Tacrolimus affects the activity of DRD2 protein]		 CTD PMID:15332494 NCBI chr 8:49,708,903...49,772,888
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Ech1 enoyl-CoA hydratase 1 decreases expression ISO Tacrolimus results in decreased expression of ECH1 mRNA CTD PMID:25270620 NCBI chr 1:84,114,494...84,120,788
Ensembl chr 1:84,112,751...84,120,795 		JBrowse link
G Edem1 ER degradation enhancing alpha-mannosidase like protein 1 increases expression ISO Tacrolimus results in increased expression of EDEM1 mRNA CTD PMID:25270620 NCBI chr 4:141,797,631...141,829,717
Ensembl chr 4:141,797,701...141,829,717 		JBrowse link
G Edn1 endothelin 1 increases expression EXP Tacrolimus results in increased expression of EDN1 mRNA; Tacrolimus results in increased expression of EDN1 protein CTD PMID:9517403 PMID:9931093 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Ednra endothelin receptor type A increases activity
increases expression		 EXP Tacrolimus results in increased activity of EDNRA protein
Tacrolimus results in increased expression of EDNRA mRNA		 CTD PMID:8587392 PMID:15964565 NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049 		JBrowse link
G Efemp2 EGF containing fibulin extracellular matrix protein 2 increases expression ISO Tacrolimus results in increased expression of EFEMP2 mRNA CTD PMID:29362864 NCBI chr 1:202,781,692...202,789,784
Ensembl chr 1:202,781,665...202,789,414 		JBrowse link
G Egr1 early growth response 1 increases expression EXP Tacrolimus results in increased expression of EGR1 mRNA CTD PMID:21865292 NCBI chr18:26,463,333...26,465,531
Ensembl chr18:26,462,981...26,466,766 		JBrowse link
G Egr2 early growth response 2 increases expression EXP Tacrolimus results in increased expression of EGR2 mRNA CTD PMID:21865292 NCBI chr20:21,051,270...21,056,322
Ensembl chr20:21,051,277...21,055,562 		JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 multiple interactions ISO Tacrolimus inhibits the reaction [Sirolimus results in decreased phosphorylation of and results in increased activity of EIF4EBP1 protein] CTD PMID:8599949 NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984 		JBrowse link
G Elac2 elaC ribonuclease Z 2 decreases expression ISO Tacrolimus results in decreased expression of ELAC2 mRNA CTD PMID:25270620 NCBI chr10:49,632,308...49,655,614
Ensembl chr10:49,632,378...49,655,614 		JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 increases phosphorylation ISO Tacrolimus results in increased phosphorylation of ERN1 protein CTD PMID:23958496 NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029 		JBrowse link
G Ero1a endoplasmic reticulum oxidoreductase 1 alpha increases expression ISO Tacrolimus results in increased expression of ERO1A mRNA CTD PMID:23958496 NCBI chr15:18,495,037...18,530,440
Ensembl chr15:18,492,945...18,530,478 		JBrowse link
G Exosc4 exosome component 4 decreases expression ISO Tacrolimus results in decreased expression of EXOSC4 mRNA CTD PMID:25270620 NCBI chr 7:108,047,831...108,050,573
Ensembl chr 7:108,047,831...108,050,573 		JBrowse link
G F2r coagulation factor II (thrombin) receptor decreases expression ISO Tacrolimus results in decreased expression of F2R mRNA CTD PMID:25270620 NCBI chr 2:26,869,343...26,885,856
Ensembl chr 2:26,868,404...26,885,870 		JBrowse link
G Fabp2 fatty acid binding protein 2 decreases expression ISO Tacrolimus results in decreased expression of FABP2 mRNA CTD PMID:25270620 NCBI chr 2:211,040,032...211,044,089
Ensembl chr 2:211,040,032...211,044,089 		JBrowse link
G Fas Fas cell surface death receptor multiple interactions ISO Tacrolimus inhibits the reaction [FAS protein results in increased activity of CASP3 protein]; Tacrolimus inhibits the reaction [FAS protein results in increased activity of CASP8 protein]; Tacrolimus inhibits the reaction [FAS protein results in increased activity of CASP9 protein] CTD PMID:15548389 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Faslg Fas ligand decreases secretion ISO Tacrolimus results in decreased secretion of FASLG protein CTD PMID:11692113 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215 		JBrowse link
G Fbln1 fibulin 1 increases expression EXP Tacrolimus results in increased expression of FBLN1 mRNA CTD PMID:21865292 NCBI chr 7:116,310,582...116,390,075
Ensembl chr 7:116,310,582...116,390,075 		JBrowse link
G Fga fibrinogen alpha chain increases expression EXP Tacrolimus results in increased expression of FGA mRNA CTD PMID:21865292 NCBI chr 2:168,365,364...168,381,533
Ensembl chr 2:168,374,120...168,381,528 		JBrowse link
G Fgb fibrinogen beta chain increases expression EXP Tacrolimus results in increased expression of FGB mRNA CTD PMID:21865292 NCBI chr 2:168,394,901...168,402,863
Ensembl chr 2:168,394,916...168,405,979 		JBrowse link
G Fgd2 FYVE, RhoGEF and PH domain containing 2 increases expression ISO Tacrolimus results in increased expression of FGD2 mRNA CTD PMID:29362864 NCBI chr20:7,424,795...7,441,603
Ensembl chr20:7,424,790...7,441,603 		JBrowse link
G Fgf21 fibroblast growth factor 21 decreases expression ISO Tacrolimus results in decreased expression of FGF21 mRNA CTD PMID:25270620 NCBI chr 1:96,083,495...96,084,738
Ensembl chr 1:96,083,441...96,090,454 		JBrowse link
G Fgl2 fibrinogen-like 2 increases expression EXP
ISO		 Tacrolimus results in increased expression of FGL2 mRNA CTD PMID:21865292 PMID:29362864 NCBI chr 4:13,710,566...13,716,207
Ensembl chr 4:13,710,575...13,716,207 		JBrowse link
G Fhl2 four and a half LIM domains 2 increases expression ISO Tacrolimus results in increased expression of FHL2 mRNA CTD PMID:29362864 NCBI chr 9:45,388,979...45,462,530
Ensembl chr 9:45,388,981...45,431,192 		JBrowse link
G Fkbp1a FKBP prolyl isomerase 1A multiple interactions
increases expression		 ISO
EXP		 [Tacrolimus binds to FKBP1A protein] inhibits the reaction [Sirolimus binds to FKBP1A protein]; [Tacrolimus inhibits the reaction [FKBP1A protein binds to ACVR1B protein]] which results in decreased ubiquitination of ACVR1B protein; Tacrolimus inhibits the reaction [FKBP1A protein binds to and results in decreased activity of ACVR1B protein]; Tacrolimus inhibits the reaction [FKBP1A protein promotes the reaction [SMURF1 protein binds to SMAD7 protein binds to ACVR1B protein]]
Tacrolimus results in increased expression of FKBP1A protein		 CTD PMID:10361256 PMID:11041285 PMID:16720724 NCBI chr 3:140,040,359...140,060,107
Ensembl chr 3:140,040,278...140,060,743 		JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 multiple interactions ISO Tacrolimus inhibits the reaction [NR3C1 protein binds to FKBP5 protein] CTD PMID:15697228 NCBI chr20:6,457,207...6,575,404
Ensembl chr20:6,457,216...6,541,674 		JBrowse link
G Flt3 Fms related receptor tyrosine kinase 3 increases expression ISO Tacrolimus results in increased expression of FLT3 mRNA CTD PMID:29362864 NCBI chr12:7,623,658...7,699,474
Ensembl chr12:7,623,930...7,699,474 		JBrowse link
G Fmo2 flavin containing dimethylaniline monoxygenase 2 increases expression ISO Tacrolimus results in increased expression of FMO2 mRNA CTD PMID:21621594 NCBI chr13:75,221,149...75,244,377
Ensembl chr13:75,224,402...75,244,308 		JBrowse link
G Fn1 fibronectin 1 multiple interactions
increases expression		 ISO Tacrolimus inhibits the reaction [NPR1 protein affects the expression of FN1 mRNA]
Tacrolimus results in increased expression of FN1 mRNA		 CTD PMID:15939815 PMID:29362864 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678 		JBrowse link
G Fndc3a fibronectin type III domain containing 3a increases expression ISO Tacrolimus results in increased expression of FNDC3A mRNA CTD PMID:25270620 NCBI chr15:47,689,909...47,867,354
Ensembl chr15:47,689,919...47,866,784 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression ISO Tacrolimus results in increased expression of FOS mRNA CTD PMID:23958496 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit increases expression ISO Tacrolimus results in increased expression of FOSL1 mRNA CTD PMID:23958496 NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930 		JBrowse link
G Gbp1 guanylate binding protein 1 decreases expression ISO Tacrolimus results in decreased expression of GBP1 mRNA CTD PMID:21621594 NCBI chr 2:231,398,136...231,432,773
Ensembl chr 2:231,398,163...231,432,131 		JBrowse link
G Gc GC, vitamin D binding protein decreases expression
increases expression		 EXP
ISO		 Tacrolimus results in decreased expression of GC mRNA
Tacrolimus results in increased expression of GC mRNA		 CTD PMID:21865292 PMID:29362864 NCBI chr14:18,632,146...18,667,563
Ensembl chr14:18,632,135...18,667,567 		JBrowse link
G Gcg glucagon multiple interactions
decreases secretion		 EXP MK0626 inhibits the reaction [Tacrolimus results in decreased secretion of GCG protein modified form] CTD PMID:24959755 NCBI chr 3:47,113,914...47,122,929
Ensembl chr 3:47,113,914...47,122,929 		JBrowse link
G Gins2 GINS complex subunit 2 increases expression ISO Tacrolimus results in increased expression of GINS2 mRNA CTD PMID:29362864 NCBI chr19:48,626,770...48,639,523
Ensembl chr19:48,626,770...48,639,339 		JBrowse link
G Gjb1 gap junction protein, beta 1 increases expression ISO Tacrolimus results in increased expression of GJB1 mRNA CTD PMID:21621594 NCBI chr  X:66,501,848...66,509,783
Ensembl chr  X:66,501,820...66,509,925 		JBrowse link
G Gldc glycine decarboxylase decreases expression ISO Tacrolimus results in decreased expression of GLDC mRNA CTD PMID:25270620 NCBI chr 1:227,883,247...227,962,119
Ensembl chr 1:227,883,249...227,962,097 		JBrowse link
G Glp1r glucagon-like peptide 1 receptor decreases expression
multiple interactions		 EXP Tacrolimus results in decreased expression of GLP1R protein
MK0626 inhibits the reaction [Tacrolimus results in decreased expression of GLP1R protein]		 CTD PMID:24959755 NCBI chr20:8,972,004...9,010,241
Ensembl chr20:8,972,004...9,010,241 		JBrowse link
G Gpihbp1 glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1 decreases expression ISO Tacrolimus results in decreased expression of GPIHBP1 mRNA CTD PMID:29362864 NCBI chr 7:107,285,584...107,288,702
Ensembl chr 7:107,285,654...107,288,702 		JBrowse link
G Gpn2 GPN-loop GTPase 2 increases expression ISO Tacrolimus results in increased expression of GPN2 mRNA CTD PMID:25270620 NCBI chr 5:145,809,455...145,817,252
Ensembl chr 5:145,809,651...145,817,252 		JBrowse link
G Gpnmb glycoprotein nmb increases expression EXP Tacrolimus results in increased expression of GPNMB mRNA CTD PMID:21865292 NCBI chr 4:78,010,247...78,031,491
Ensembl chr 4:78,010,197...78,049,367 		JBrowse link
G Grn granulin precursor increases expression ISO Tacrolimus results in increased expression of GRN mRNA CTD PMID:25270620 NCBI chr10:87,387,672...87,393,777
Ensembl chr10:87,387,638...87,393,775 		JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha multiple interactions
increases phosphorylation		 ISO [GSK3A protein co-treated with GSK3B protein] affects the reaction [Tacrolimus results in increased expression of SNAI1 protein]
Tacrolimus results in increased phosphorylation of GSK3A protein		 CTD PMID:22416070 NCBI chr 1:80,815,843...80,825,732
Ensembl chr 1:80,815,850...80,825,802 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions
increases phosphorylation		 ISO [GSK3A protein co-treated with GSK3B protein] affects the reaction [Tacrolimus results in increased expression of SNAI1 protein]
Tacrolimus results in increased phosphorylation of GSK3B protein		 CTD PMID:22416070 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Gtpbp4 GTP binding protein 4 decreases expression EXP Tacrolimus results in decreased expression of GTPBP4 mRNA CTD PMID:21865292 NCBI chr17:61,308,033...61,328,184
Ensembl chr17:61,308,014...61,418,009 		JBrowse link
G Guca2a guanylate cyclase activator 2A increases expression EXP Tacrolimus results in increased expression of GUCA2A mRNA CTD PMID:21865292 NCBI chr 5:133,237,177...133,239,019
Ensembl chr 5:133,237,177...133,239,018 		JBrowse link
G Hadhb hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta decreases expression ISO Tacrolimus results in decreased expression of HADHB mRNA CTD PMID:25270620 NCBI chr 6:26,153,572...26,187,668
Ensembl chr 6:26,153,578...26,184,869 		JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 increases expression EXP Tacrolimus results in increased expression of HAVCR1 mRNA CTD PMID:21865292 NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698 		JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 increases expression ISO Tacrolimus results in increased expression of HERPUD1 mRNA CTD PMID:23958496 PMID:25270620 NCBI chr19:10,598,411...10,609,002
Ensembl chr19:10,598,417...10,618,424 		JBrowse link
G Hexa hexosaminidase subunit alpha increases expression ISO Tacrolimus results in increased expression of HEXA mRNA CTD PMID:25270620 NCBI chr 8:59,936,526...59,961,654
Ensembl chr 8:59,936,660...59,962,013 		JBrowse link
G Hgs hepatocyte growth factor-regulated tyrosine kinase substrate increases expression ISO Tacrolimus results in increased expression of HGS mRNA CTD PMID:29380240 NCBI chr10:105,739,617...105,757,838
Ensembl chr10:105,739,296...105,757,835 		JBrowse link
G Hk2 hexokinase 2 increases expression ISO Tacrolimus results in increased expression of HK2 mRNA CTD PMID:29362864 NCBI chr 4:115,234,509...115,283,530
Ensembl chr 4:115,234,509...115,283,530 		JBrowse link
G Hk3 hexokinase 3 increases expression ISO Tacrolimus results in increased expression of HK3 mRNA CTD PMID:29362864 NCBI chr17:9,596,950...9,614,847
Ensembl chr17:9,599,865...9,614,863 		JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 decreases expression ISO Tacrolimus results in decreased expression of HMGCS2 mRNA CTD PMID:25270620 NCBI chr 2:185,875,609...185,903,505
Ensembl chr 2:185,875,616...185,902,130 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression
decreases expression
multiple interactions		 ISO
EXP		 Tacrolimus results in increased expression of HMOX1 mRNA; Tacrolimus results in increased expression of HMOX1 protein
Tacrolimus results in decreased expression of HMOX1 protein
MK0626 inhibits the reaction [Tacrolimus results in decreased expression of HMOX1 protein]		 CTD PMID:23958496 PMID:24959755 PMID:26260164 PMID:29362864 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hnf1b HNF1 homeobox B decreases expression ISO Tacrolimus results in decreased expression of HNF1B mRNA CTD PMID:22416070 NCBI chr10:68,735,894...68,789,888
Ensembl chr10:68,735,894...68,789,888 		JBrowse link
G Hsdl2 hydroxysteroid dehydrogenase like 2 decreases expression ISO Tacrolimus results in decreased expression of HSDL2 mRNA CTD PMID:25270620 NCBI chr 5:74,443,933...74,479,104
Ensembl chr 5:74,443,872...74,479,839 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression ISO Tacrolimus results in increased expression of HSPA5 mRNA CTD PMID:25270620 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891 		JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 multiple interactions
increases expression		 EXP Tacrolimus inhibits the reaction [Acrylamide results in decreased expression of HSPA8 protein]
Tacrolimus results in increased expression of HSPA8 protein		 CTD PMID:15081597 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259 		JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A decreases expression ISO Tacrolimus results in decreased expression of HTR1A protein CTD PMID:27606422 NCBI chr 2:36,694,174...36,695,442
Ensembl chr 2:36,694,174...36,695,442 		JBrowse link
G Htr1b 5-hydroxytryptamine receptor 1B decreases expression ISO Tacrolimus results in decreased expression of HTR1B protein CTD PMID:27606422 NCBI chr 8:82,513,572...82,534,892
Ensembl chr 8:82,517,360...82,534,549 		JBrowse link
G Icam1 intercellular adhesion molecule 1 decreases expression
increases expression		 EXP
ISO		 Tacrolimus results in decreased expression of ICAM1; Tacrolimus results in decreased expression of ICAM1 protein
Tacrolimus results in increased expression of ICAM1 mRNA		 CTD PMID:9794552 PMID:10385251 PMID:23958496 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein increases expression ISO Tacrolimus results in increased expression of ID1 mRNA CTD PMID:25270620 PMID:29362864 NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419 		JBrowse link
G Id2 inhibitor of DNA binding 2 increases expression ISO Tacrolimus results in increased expression of ID2 mRNA CTD PMID:25270620 NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400 		JBrowse link
G Id3 inhibitor of DNA binding 3, HLH protein increases expression ISO Tacrolimus results in increased expression of ID3 mRNA CTD PMID:29362864 NCBI chr 5:148,372,784...148,374,353
Ensembl chr 5:148,372,762...148,374,349 		JBrowse link
G Id4 inhibitor of DNA binding 4, HLH protein increases expression ISO Tacrolimus results in increased expression of ID4 mRNA CTD PMID:25270620 NCBI chr17:16,389,387...16,391,956
Ensembl chr17:16,389,387...16,392,470 		JBrowse link
G Idi1 isopentenyl-diphosphate delta isomerase 1 decreases expression ISO Tacrolimus results in decreased expression of IDI1 mRNA CTD PMID:25270620 NCBI chr17:61,629,592...61,637,357
Ensembl chr17:61,629,594...61,637,357 		JBrowse link
G Ifi27l2b interferon, alpha-inducible protein 27 like 2B increases expression ISO Tacrolimus results in increased expression of IFI27L2A mRNA CTD PMID:29362864 NCBI chr 6:122,598,872...122,600,358
Ensembl chr 6:122,598,872...122,600,360 		JBrowse link
G Ifng interferon gamma multiple interactions
decreases expression
decreases secretion		 ISO
EXP		 [Tacrolimus co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; Tacrolimus inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IFNG protein]; Tacrolimus inhibits the reaction [enterotoxin A, Staphylococcal results in increased expression of IFNG protein]; Tacrolimus inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IFNG mRNA]
Tacrolimus results in decreased expression of IFNG protein
Tacrolimus results in decreased expression of IFNG mRNA; Tacrolimus results in decreased expression of IFNG protein
[Tacrolimus co-treated with TAK 779] results in decreased expression of IFNG protein
Tacrolimus inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in decreased expression of BCL2 protein]; Tacrolimus inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased activity of CASP3 protein]; Tacrolimus inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of BAX protein]; Tacrolimus inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of TRP53 protein]
Tacrolimus results in decreased secretion of IFNG protein		 CTD PMID:1371491 PMID:8986461 PMID:10205001 PMID:11407316 PMID:11692113 More... NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Igf1 insulin-like growth factor 1 increases response to substance EXP IGF1 protein results in increased susceptibility to Tacrolimus CTD PMID:12826230 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 decreases expression
increases expression		 EXP Tacrolimus results in decreased expression of IGFBP1 mRNA
Tacrolimus results in increased expression of IGFBP1 mRNA		 CTD PMID:21865292 NCBI chr14:82,047,415...82,052,482
Ensembl chr14:82,047,415...82,052,482 		JBrowse link
G Igfbp5 insulin-like growth factor binding protein 5 increases expression EXP Tacrolimus results in increased expression of IGFBP5 mRNA CTD PMID:21865292 NCBI chr 9:74,452,371...74,464,953
Ensembl chr 9:74,448,382...74,465,156 		JBrowse link
G Il15ra interleukin 15 receptor subunit alpha increases expression ISO Tacrolimus results in increased expression of IL15RA mRNA CTD PMID:23958496 NCBI chr17:66,802,300...66,831,973
Ensembl chr17:66,802,334...66,832,278 		JBrowse link
G Il17ra interleukin 17 receptor A increases expression ISO Tacrolimus results in increased expression of IL17RA mRNA CTD PMID:23958496 NCBI chr 4:153,667,534...153,690,174
Ensembl chr 4:153,667,534...153,690,174 		JBrowse link
G Il1b interleukin 1 beta increases expression ISO Tacrolimus results in increased expression of IL1B mRNA CTD PMID:29594315 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il1rn interleukin 1 receptor antagonist increases expression ISO Tacrolimus results in increased expression of IL1RN mRNA CTD PMID:23958496 NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445 		JBrowse link
G Il2 interleukin 2 multiple interactions
decreases expression		 ISO
EXP		 [Tacrolimus co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; Tacrolimus inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL2 protein]; Tacrolimus inhibits the reaction [CD2 protein results in increased expression of IL2 protein]; Tacrolimus inhibits the reaction [enterotoxin A, Staphylococcal results in increased expression of IL2 protein]; Tacrolimus inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL2 mRNA]; Tacrolimus inhibits the reaction [Zinc Sulfate inhibits the reaction [Mitogens results in increased expression of IL2 mRNA]]
Tacrolimus results in decreased expression of IL2 mRNA; Tacrolimus results in decreased expression of IL2 protein
Tacrolimus affects the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] affects the expression of IL2 protein]; Tacrolimus inhibits the reaction [Sirolimus inhibits the reaction [IL2 protein results in increased phosphorylation of RPS6 protein]]		 CTD PMID:1371491 PMID:1614535 PMID:1701765 PMID:1705513 PMID:8986461 More... NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566 		JBrowse link
G Il23a interleukin 23 subunit alpha increases expression ISO Tacrolimus results in increased expression of IL23A mRNA CTD PMID:25270620 NCBI chr 7:721,809...723,923
Ensembl chr 7:721,809...723,923 		JBrowse link
G Il2ra interleukin 2 receptor subunit alpha decreases expression ISO Tacrolimus results in decreased expression of IL2RA protein CTD PMID:1701765 NCBI chr17:66,849,974...66,898,665
Ensembl chr17:66,849,974...66,898,697 		JBrowse link
G Il3 interleukin 3 decreases expression
multiple interactions		 ISO Tacrolimus results in decreased expression of IL3 protein
Sirolimus inhibits the reaction [Tacrolimus inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL3 protein]]; Tacrolimus inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL3 protein]		 CTD PMID:1376361 PMID:11407316 NCBI chr10:38,405,716...38,408,066
Ensembl chr10:38,405,716...38,408,066 		JBrowse link
G Il4 interleukin 4 multiple interactions
decreases expression		 ISO
EXP		 Tacrolimus inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL4 protein]
Tacrolimus results in decreased expression of IL4 mRNA; Tacrolimus results in decreased expression of IL4 protein
Tacrolimus inhibits the reaction [bisphenol A promotes the reaction [NFATC3 protein binds to IL4 promoter]]; Tacrolimus inhibits the reaction [bisphenol A results in increased expression of IL4 protein]; Tacrolimus inhibits the reaction [nonylphenol promotes the reaction [NFATC3 protein binds to IL4 promoter]]; Tacrolimus inhibits the reaction [nonylphenol results in increased expression of IL4 protein]		 CTD PMID:1371491 PMID:10685002 PMID:11407316 PMID:12709020 PMID:16368244 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Il5 interleukin 5 multiple interactions
decreases expression		 ISO Tacrolimus inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL5 protein]
Tacrolimus results in decreased expression of IL5 mRNA; Tacrolimus results in decreased expression of IL5 protein		 CTD PMID:1371491 PMID:7540862 PMID:11407316 PMID:15948978 NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213 		JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression
decreases expression		 EXP
ISO		 [Tacrolimus co-treated with quinapril] results in decreased expression of IL6 protein; [Tacrolimus co-treated with quinapril] results in increased expression of IL6 protein; [Tacrolimus co-treated with Valsartan] results in decreased expression of IL6 protein; [Tacrolimus co-treated with Valsartan] results in increased expression of IL6 protein
Tacrolimus results in increased expression of IL6 mRNA
parthenolide inhibits the reaction [Tacrolimus results in increased expression of IL6 mRNA]; sulforaphane inhibits the reaction [Tacrolimus results in increased expression of IL6 mRNA]
Tacrolimus results in increased expression of IL6 protein
Tacrolimus results in decreased expression of IL6 protein		 CTD PMID:16549154 PMID:23958496 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Imp4 IMP U3 small nucleolar ribonucleoprotein 4 decreases expression ISO Tacrolimus results in decreased expression of IMP4 mRNA CTD PMID:25270620 NCBI chr 9:36,654,127...36,659,265
Ensembl chr 9:36,654,401...36,660,075 		JBrowse link
G Ino80e INO80 complex subunit E decreases expression ISO Tacrolimus results in decreased expression of INO80E mRNA CTD PMID:25270620 NCBI chr 1:181,461,406...181,472,059
Ensembl chr 1:181,461,408...181,472,469 		JBrowse link
G Ins2 insulin 2 decreases expression ISO Tacrolimus results in decreased expression of INS protein CTD PMID:17391142 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775 		JBrowse link
G Irak1 interleukin-1 receptor-associated kinase 1 increases phosphorylation ISO Tacrolimus results in increased phosphorylation of IRAK1 protein CTD PMID:23958496 NCBI chr  X:151,768,621...151,778,521
Ensembl chr  X:151,768,777...151,778,521 		JBrowse link
G Itgal integrin subunit alpha L decreases expression EXP Tacrolimus results in decreased expression of ITGAL CTD PMID:9794552 NCBI chr 1:181,918,183...181,955,735
Ensembl chr 1:181,918,183...181,955,732 		JBrowse link
G Jak2 Janus kinase 2 increases phosphorylation ISO Tacrolimus results in increased phosphorylation of JAK2 protein CTD PMID:23958496 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit decreases expression EXP Tacrolimus results in decreased expression of JUN protein CTD PMID:9674596 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit increases expression ISO Tacrolimus results in increased expression of JUNB mRNA CTD PMID:23958496 NCBI chr19:23,176,265...23,178,049
E