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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:galactolipid
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Accession:CHEBI:5254 term browser browse the term
Definition:A glycolipid and which the glyco component is specified as galactosyl.



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1-O-(alpha-D-galactosyl)-N-hexacosanoylphytosphingosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CXCL10 C-X-C motif chemokine ligand 10 increases expression EXP KRN 7000 results in increased expression of CXCL10 protein CTD PMID:15867097 NCBI chr 4:76,021,118...76,023,497
Ensembl chr 4:76,021,118...76,023,497
JBrowse link
G IL12B interleukin 12B increases expression EXP KRN 7000 results in increased expression of IL12B protein CTD PMID:15867097 NCBI chr 5:159,314,780...159,330,487
Ensembl chr 5:159,314,780...159,330,487
JBrowse link
alpha-galactosylceramide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GATA3 GATA binding protein 3 multiple interactions ISO [Ovalbumin co-treated with alpha-galactosylceramide] results in decreased expression of GATA3 mRNA CTD PMID:30803854 NCBI chr10:8,045,420...8,075,198
Ensembl chr10:8,045,378...8,075,198
JBrowse link
G GPT glutamic--pyruvic transaminase multiple interactions ISO [Floxacillin co-treated with alpha-galactosylceramide] results in increased expression of GPT protein CTD PMID:30993380 NCBI chr 8:144,503,068...144,507,172
Ensembl chr 8:144,502,973...144,507,174
JBrowse link
G IFNG interferon gamma multiple interactions
increases secretion
ISO [Alcohols co-treated with alpha-galactosylceramide] results in increased expression of IFNG protein; [Ovalbumin co-treated with alpha-galactosylceramide] results in increased secretion of IFNG protein
alpha-galactosylceramide results in increased secretion of IFNG protein
CTD PMID:12482940 PMID:25499027 PMID:30803854 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740
JBrowse link
G IL10 interleukin 10 multiple interactions ISO [Ovalbumin co-treated with alpha-galactosylceramide] results in decreased secretion of IL10 protein CTD PMID:30803854 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541
JBrowse link
G IL13 interleukin 13 multiple interactions ISO [Ovalbumin co-treated with alpha-galactosylceramide] results in decreased secretion of IL13 protein CTD PMID:30803854 NCBI chr 5:132,656,522...132,661,110
Ensembl chr 5:132,656,263...132,661,110
JBrowse link
G IL17A interleukin 17A multiple interactions ISO [Ovalbumin co-treated with alpha-galactosylceramide] results in decreased secretion of IL17A protein CTD PMID:30803854 NCBI chr 6:52,186,375...52,190,638
Ensembl chr 6:52,186,375...52,190,638
JBrowse link
G IL4 interleukin 4 increases secretion
multiple interactions
ISO alpha-galactosylceramide results in increased secretion of IL4 protein
[Ovalbumin co-treated with alpha-galactosylceramide] results in decreased secretion of IL4 protein
CTD PMID:12482940 PMID:30803854 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678
JBrowse link
G IL5 interleukin 5 multiple interactions ISO [Ovalbumin co-treated with alpha-galactosylceramide] results in decreased secretion of IL5 protein CTD PMID:30803854 NCBI chr 5:132,539,194...132,556,864
Ensembl chr 5:132,541,445...132,556,838
JBrowse link
G KLRF2 killer cell lectin like receptor F2 decreases expression ISO alpha-galactosylceramide results in decreased expression of KLRB1C protein CTD PMID:30993380 NCBI chr12:9,881,489...9,895,833
Ensembl chr12:9,881,489...9,895,833
JBrowse link
G RORC RAR related orphan receptor C multiple interactions ISO [Ovalbumin co-treated with alpha-galactosylceramide] results in decreased expression of RORC mRNA alternative form CTD PMID:30803854 NCBI chr 1:151,806,071...151,832,451
Ensembl chr 1:151,806,071...151,831,845
JBrowse link
G TBX21 T-box transcription factor 21 multiple interactions ISO [Ovalbumin co-treated with alpha-galactosylceramide] results in increased expression of TBX21 mRNA CTD PMID:30803854 NCBI chr17:47,733,236...47,746,122
Ensembl chr17:47,733,236...47,746,122
JBrowse link
phytosphingosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AIFM1 apoptosis inducing factor mitochondria associated 1 affects localization
multiple interactions
EXP phytosphingosine affects the localization of AIFM1 protein
3,4-dihydro-5-(4-(1-piperidinyl)butoxy)-1(2H)-isoquinolinone inhibits the reaction [phytosphingosine affects the localization of AIFM1 protein]
CTD PMID:15486061 NCBI chr  X:130,129,362...130,165,841
Ensembl chr  X:130,124,666...130,165,879
JBrowse link
G BAX BCL2 associated X, apoptosis regulator multiple interactions
affects localization
EXP 3,4-dihydro-5-(4-(1-piperidinyl)butoxy)-1(2H)-isoquinolinone inhibits the reaction [[arsenic trioxide co-treated with phytosphingosine] results in increased localization of BAX protein]; [arsenic trioxide co-treated with phytosphingosine] results in increased localization of BAX protein; Acetylcysteine inhibits the reaction [[arsenic trioxide co-treated with phytosphingosine] results in increased localization of BAX protein]; SB 203580 inhibits the reaction [[arsenic trioxide co-treated with phytosphingosine] results in increased localization of BAX protein]
phytosphingosine affects the localization of BAX protein
CTD PMID:15486061 PMID:17237268 NCBI chr19:48,954,825...48,961,798
Ensembl chr19:48,954,815...48,961,798
JBrowse link
G CASP3 caspase 3 multiple interactions EXP 3,4-dihydro-5-(4-(1-piperidinyl)butoxy)-1(2H)-isoquinolinone inhibits the reaction [[arsenic trioxide co-treated with phytosphingosine] results in increased activity of CASP3 protein]; [arsenic trioxide co-treated with phytosphingosine] results in increased activity of CASP3 protein; SB 203580 inhibits the reaction [[arsenic trioxide co-treated with phytosphingosine] results in increased activity of CASP3 protein] CTD PMID:17237268 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,649,509
JBrowse link
G CASP9 caspase 9 multiple interactions EXP 3,4-dihydro-5-(4-(1-piperidinyl)butoxy)-1(2H)-isoquinolinone inhibits the reaction [[arsenic trioxide co-treated with phytosphingosine] results in increased activity of CASP9 protein]; [arsenic trioxide co-treated with phytosphingosine] results in increased activity of CASP9 protein; SB 203580 inhibits the reaction [[arsenic trioxide co-treated with phytosphingosine] results in increased activity of CASP9 protein] CTD PMID:17237268 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 multiple interactions EXP [arsenic trioxide co-treated with phytosphingosine] results in decreased phosphorylation of MAPK1 protein CTD PMID:17237268 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680
JBrowse link
G MAPK14 mitogen-activated protein kinase 14 multiple interactions EXP 3,4-dihydro-5-(4-(1-piperidinyl)butoxy)-1(2H)-isoquinolinone inhibits the reaction [[arsenic trioxide co-treated with phytosphingosine] results in increased phosphorylation of MAPK14 protein]; [arsenic trioxide co-treated with phytosphingosine] results in increased phosphorylation of MAPK14 protein; Acetylcysteine inhibits the reaction [[arsenic trioxide co-treated with phytosphingosine] results in increased phosphorylation of MAPK14 protein] CTD PMID:17237268 NCBI chr 6:36,027,711...36,122,964
Ensembl chr 6:36,027,677...36,111,236
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions EXP [arsenic trioxide co-treated with phytosphingosine] results in decreased phosphorylation of MAPK3 protein CTD PMID:17237268 NCBI chr16:30,114,105...30,123,309
Ensembl chr16:30,114,105...30,123,506
JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 multiple interactions
increases activity
EXP 3,4-dihydro-5-(4-(1-piperidinyl)butoxy)-1(2H)-isoquinolinone inhibits the reaction [[Arsenic Trioxide co-treated with phytosphingosine] results in increased activity of PARP1 protein]; [Arsenic Trioxide co-treated with phytosphingosine] results in increased activity of PARP1 protein; [Arsenic Trioxide co-treated with phytosphingosine] results in increased cleavage of PARP1 protein; Acetylcysteine inhibits the reaction [[Arsenic Trioxide co-treated with phytosphingosine] results in increased activity of PARP1 protein]
phytosphingosine results in increased activity of PARP1 protein
CTD PMID:15486061 PMID:17237268 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 25189
    chemical entity 25160
      atom 25151
        nonmetal atom 24676
          carbon atom 24571
            organic molecular entity 24571
              lipid 20153
                liposaccharide 2089
                  glycolipid 54
                    galactolipid 21
                      N-(docosanoyl)-1-(2',3',4',6'-tetraacetylbeta-D-galactosyl)-3-acetylsphingosine 0
                      alpha-D-galactosyl-N-(hexacosanoyl)-11,12-methylene-C22-sphinganine 0
                      alpha-galactosylsphingamide + 0
                      galactosylceramide + 21
Path 2
Term Annotations click to browse term
  CHEBI ontology 25189
    subatomic particle 25151
      composite particle 25151
        hadron 25151
          baryon 25151
            nucleon 25151
              atomic nucleus 25151
                atom 25151
                  main group element atom 25031
                    p-block element atom 25031
                      carbon group element atom 24607
                        carbon atom 24571
                          organic molecular entity 24571
                            heteroorganic entity 23992
                              organochalcogen compound 23570
                                organooxygen compound 23371
                                  carbohydrates and carbohydrate derivatives 13172
                                    carbohydrate 13172
                                      carbohydrate derivative 12770
                                        liposaccharide 2089
                                          glycolipid 54
                                            galactolipid 21
                                              N-(docosanoyl)-1-(2',3',4',6'-tetraacetylbeta-D-galactosyl)-3-acetylsphingosine 0
                                              alpha-D-galactosyl-N-(hexacosanoyl)-11,12-methylene-C22-sphinganine 0
                                              alpha-galactosylsphingamide + 0
                                              galactosylceramide + 21
paths to the root