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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:haloindole
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Accession:CHEBI:52507 term browser browse the term
Definition:A compound based on an indole skeleton, containing one or more halogen atoms
Synonyms:related_synonym: haloindoles



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680C91 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO TDO inhibitor LM10 inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of CYP1A1 mRNA] CTD PMID:24930766 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G H2ax H2A.X variant histone decreases expression ISO TDO inhibitor LM10 results in decreased expression of H2AX protein modified form CTD PMID:26651356 NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239
JBrowse link
G Polk DNA polymerase kappa decreases expression ISO TDO inhibitor LM10 results in decreased expression of POLK protein CTD PMID:26651356 NCBI chr 2:27,822,228...27,882,331
Ensembl chr 2:27,822,679...27,882,313
JBrowse link
G Tdo2 tryptophan 2,3-dioxygenase decreases activity ISO TDO inhibitor LM10 results in decreased activity of TDO2 protein CTD PMID:21726069 NCBI chr 2:167,269,581...167,287,511
Ensembl chr 2:167,269,579...167,287,511
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19918
    chemical entity 19916
      atom 19916
        nonmetal atom 19852
          nitrogen atom 19013
            nitrogen molecular entity 19013
              organonitrogen compound 18856
                organonitrogen heterocyclic compound 18192
                  benzopyrrole 9742
                    indoles 9430
                      haloindole 4
                        bromoindole + 0
                        chloroindole + 0
                        fluoroindole + 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 19918
    subatomic particle 19916
      composite particle 19916
        hadron 19916
          baryon 19916
            nucleon 19916
              atomic nucleus 19916
                atom 19916
                  main group element atom 19866
                    p-block element atom 19866
                      carbon group element atom 19811
                        carbon atom 19806
                          organic molecular entity 19806
                            organic molecule 19758
                              organic cyclic compound 19565
                                organic heterocyclic compound 18906
                                  organic heteropolycyclic compound 18334
                                    organic heterobicyclic compound 17279
                                      benzopyrrole 9742
                                        indoles 9430
                                          haloindole 4
                                            bromoindole + 0
                                            chloroindole + 0
                                            fluoroindole + 4
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