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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:52449 term browser browse the term
Definition:An oxoicosatetraenoic acid having a 5-oxo group; and (6E)-, (8Z), (11Z)- and (14Z)-double bonds.
Synonyms:related_synonym: (6E,8Z,11Z,14Z)-5-Oxoicosa-6,8,11,14-tetraenoic acid;   5-KETE;   5-Oxo-icosa-6,8,11,14-tetraenoic acid;   5-OxoETE;   5-Oxoeicosatetraenoic acid;   5-Oxoicosatetraenoic acid;   5-keto-ETE;   5-ketoeicosatetraenoic acid;   5-oxo, 6t,8c,11c,14c-20:4;   5-oxo-6(E),8(Z),11(Z),14(Z)-eicosatetraenoic acid;   5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid;   Formula=C20H30O3;   InChI=1S/C20H30O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-16-19(21)17-15-18-20(22)23/h6-7,9-10,12-14,16H,2-5,8,11,15,17-18H2,1H3,(H,22,23)/b7-6-,10-9-,13-12-,16-14+;   InChIKey=MEASLHGILYBXFO-XTDASVJISA-N;   SMILES=CCCCC\\C=C/C\\C=C/C\\C=C/C=C/C(=O)CCCC(O)=O;   eicosa-5,8,12,14-tetraenoic acid
 alt_id: CHEBI:120616;   CHEBI:34460;   CHEBI:52287;   CHEBI:60950
 xref: HMDB:HMDB0010217;   KEGG:C14732;   LIPID_MAPS_instance:LMFA03060011
 xref_mesh: MESH:C080828
 xref: PMID:15893379;   PMID:16159627;   PMID:19450703;   PMID:3599023;   PMID:8906847;   Reaxys:6213921
 cyclic_relationship: is_conjugate_acid_of CHEBI:65342

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5-oxo-ETE term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Csf2 colony stimulating factor 2 increases secretion ISO 5-oxo-6,8,11,14-eicosatetraenoic acid results in increased secretion of CSF2 protein CTD PMID:15136573 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
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Term Annotations click to browse term
  CHEBI ontology 19800
    role 19751
      biological role 19751
        immunomodulator 14908
          5-oxo-ETE 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19800
    subatomic particle 19799
      composite particle 19799
        hadron 19799
          baryon 19799
            nucleon 19799
              atomic nucleus 19799
                atom 19799
                  main group element atom 19698
                    p-block element atom 19698
                      carbon group element atom 19619
                        carbon atom 19609
                          organic molecular entity 19609
                            organic group 18718
                              organic divalent group 18702
                                organodiyl group 18702
                                  carbonyl group 18651
                                    carbonyl compound 18651
                                      carboxylic acid 18346
                                        monocarboxylic acid 17622
                                          fatty acid 16011
                                            unsaturated fatty acid 957
                                              polyunsaturated fatty acid 692
                                                fatty acid 20:4 331
                                                  icosatetraenoic acid 331
                                                    icosa-6,8,11,14-tetraenoic acid 1
                                                      5-oxo-ETE 1
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