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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:52449 term browser browse the term
Definition:An oxoicosatetraenoic acid having a 5-oxo group; and (6E)-, (8Z), (11Z)- and (14Z)-double bonds.
Synonyms:related_synonym: (6E,8Z,11Z,14Z)-5-Oxoicosa-6,8,11,14-tetraenoic acid;   5-KETE;   5-Oxo-icosa-6,8,11,14-tetraenoic acid;   5-OxoETE;   5-Oxoeicosatetraenoic acid;   5-Oxoicosatetraenoic acid;   5-keto-ETE;   5-ketoeicosatetraenoic acid;   5-oxo, 6t,8c,11c,14c-20:4;   5-oxo-6(E),8(Z),11(Z),14(Z)-eicosatetraenoic acid;   5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid;   Formula=C20H30O3;   InChI=1S/C20H30O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-16-19(21)17-15-18-20(22)23/h6-7,9-10,12-14,16H,2-5,8,11,15,17-18H2,1H3,(H,22,23)/b7-6-,10-9-,13-12-,16-14+;   InChIKey=MEASLHGILYBXFO-XTDASVJISA-N;   SMILES=CCCCC\\C=C/C\\C=C/C\\C=C/C=C/C(=O)CCCC(O)=O;   eicosa-5,8,12,14-tetraenoic acid
 alt_id: CHEBI:120616;   CHEBI:34460;   CHEBI:52287;   CHEBI:60950
 xref: HMDB:HMDB0010217;   KEGG:C14732;   LIPID_MAPS_instance:LMFA03060011
 xref_mesh: MESH:C080828
 xref: PMID:15893379;   PMID:16159627;   PMID:19450703;   PMID:3599023;   PMID:8906847;   Reaxys:6213921
 cyclic_relationship: is_conjugate_acid_of CHEBI:65342

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5-oxo-ETE term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Csf2 colony stimulating factor 2 increases secretion ISO 5-oxo-6,8,11,14-eicosatetraenoic acid results in increased secretion of CSF2 protein CTD PMID:15136573 NCBI chr10:39,602,089...39,604,070
Ensembl chr10:39,602,089...39,604,070
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Term Annotations click to browse term
  CHEBI ontology 19841
    role 19792
      biological role 19792
        immunomodulator 13740
          5-oxo-ETE 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19841
    subatomic particle 19839
      composite particle 19839
        hadron 19839
          baryon 19839
            nucleon 19839
              atomic nucleus 19839
                atom 19839
                  main group element atom 19732
                    p-block element atom 19732
                      carbon group element atom 19636
                        carbon atom 19625
                          organic molecular entity 19625
                            organic group 18537
                              organic divalent group 18528
                                organodiyl group 18528
                                  carbonyl group 18436
                                    carbonyl compound 18436
                                      carboxylic acid 18113
                                        monocarboxylic acid 17483
                                          fatty acid 16001
                                            unsaturated fatty acid 937
                                              polyunsaturated fatty acid 674
                                                fatty acid 20:4 327
                                                  icosatetraenoic acid 327
                                                    icosa-6,8,11,14-tetraenoic acid 1
                                                      5-oxo-ETE 1
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