Send us a Message

Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   


The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

go back to main search page
Accession:CHEBI:52449 term browser browse the term
Definition:An oxoicosatetraenoic acid having a 5-oxo group; and (6E)-, (8Z), (11Z)- and (14Z)-double bonds.
Synonyms:related_synonym: (6E,8Z,11Z,14Z)-5-Oxoicosa-6,8,11,14-tetraenoic acid;   5-KETE;   5-Oxo-icosa-6,8,11,14-tetraenoic acid;   5-OxoETE;   5-Oxoeicosatetraenoic acid;   5-Oxoicosatetraenoic acid;   5-keto-ETE;   5-ketoeicosatetraenoic acid;   5-oxo, 6t,8c,11c,14c-20:4;   5-oxo-6(E),8(Z),11(Z),14(Z)-eicosatetraenoic acid;   5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid;   Formula=C20H30O3;   InChI=1S/C20H30O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-16-19(21)17-15-18-20(22)23/h6-7,9-10,12-14,16H,2-5,8,11,15,17-18H2,1H3,(H,22,23)/b7-6-,10-9-,13-12-,16-14+;   InChIKey=MEASLHGILYBXFO-XTDASVJISA-N;   SMILES=CCCCC\\C=C/C\\C=C/C\\C=C/C=C/C(=O)CCCC(O)=O;   eicosa-5,8,12,14-tetraenoic acid
 alt_id: CHEBI:120616;   CHEBI:34460;   CHEBI:52287;   CHEBI:60950
 xref: HMDB:HMDB0010217;   KEGG:C14732;   LIPID_MAPS_instance:LMFA03060011
 xref_mesh: MESH:C080828
 xref: PMID:15893379;   PMID:16159627;   PMID:19450703;   PMID:3599023;   PMID:8906847;   Reaxys:6213921
 cyclic_relationship: is_conjugate_acid_of CHEBI:65342

show annotations for term's descendants           Sort by:
5-oxo-ETE term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Csf2 colony stimulating factor 2 increases secretion ISO 5-oxo-6,8,11,14-eicosatetraenoic acid results in increased secretion of CSF2 protein CTD PMID:15136573 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19838
    role 19810
      biological role 19808
        immunomodulator 15057
          5-oxo-ETE 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19838
    subatomic particle 19836
      composite particle 19836
        hadron 19836
          baryon 19836
            nucleon 19836
              atomic nucleus 19836
                atom 19836
                  main group element atom 19782
                    p-block element atom 19782
                      carbon group element atom 19722
                        carbon atom 19719
                          organic molecular entity 19719
                            heteroorganic entity 19474
                              organochalcogen compound 19262
                                organooxygen compound 19153
                                  carbon oxoacid 18647
                                    carboxylic acid 18620
                                      monocarboxylic acid 17994
                                        fatty acid 16843
                                          unsaturated fatty acid 1666
                                            polyunsaturated fatty acid 839
                                              fatty acid 20:4 361
                                                icosatetraenoic acid 361
                                                  icosa-6,8,11,14-tetraenoic acid 1
                                                    5-oxo-ETE 1
paths to the root