Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:alpha-oxyketone
go back to main search page
Accession:CHEBI:52396 term browser browse the term
Definition:An oxyketone with the general formula R2C(=O) (R=/=H) where one or more of the R groups contains an oxy (-O-) group and the oxy and carbonyl groups are bonded to the same carbon atom.
Synonyms:related_synonym: alpha-oxyketones


show annotations for term's descendants           Sort by:
 
aldosterone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGT angiotensinogen multiple interactions
increases secretion
EXP 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer inhibits the reaction [AGT protein results in increased secretion of Aldosterone]; Enkephalin, D-Penicillamine (2,5)- inhibits the reaction [AGT protein results in increased secretion of Aldosterone] CTD PMID:22100847 NCBI chr14:59,643,030...59,656,835
Ensembl chr14:59,643,292...59,672,428
JBrowse link
G ATP1A1 ATPase Na+/K+ transporting subunit alpha 1 increases expression EXP Aldosterone results in increased expression of ATP1A1 protein CTD PMID:28438630 NCBI chr 4:104,353,506...104,384,321
Ensembl chr 4:104,353,506...104,384,606
JBrowse link
G GCLC glutamate-cysteine ligase catalytic subunit increases expression EXP Aldosterone results in increased expression of GCLC protein CTD PMID:24512358 NCBI chr 7:27,209,565...27,253,535
Ensembl chr 7:27,209,564...27,253,535
JBrowse link
G HMOX1 heme oxygenase 1 increases expression EXP Aldosterone results in increased expression of HMOX1 protein CTD PMID:24512358
G NFE2L2 nuclear factor, erythroid 2 like 2 multiple interactions EXP 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Aldosterone results in increased activity of NFE2L2 protein]; 3-benzyl-7-(2-benzoxazolyl)thio-1,2,3-triazolo(4,5-d)pyrimidine inhibits the reaction [Aldosterone results in increased activity of NFE2L2 protein]; acetovanillone inhibits the reaction [Aldosterone results in increased activity of NFE2L2 protein]; Acetylcysteine inhibits the reaction [Aldosterone results in increased activity of NFE2L2 protein]; Aldosterone results in increased expression of and results in increased activity of NFE2L2 protein; diphenyleneiodonium inhibits the reaction [Aldosterone results in increased activity of NFE2L2 protein]; Eplerenone inhibits the reaction [Aldosterone results in increased activity of NFE2L2 protein]; Ro 32-0432 inhibits the reaction [Aldosterone results in increased activity of NFE2L2 protein]; tempol inhibits the reaction [Aldosterone results in increased activity of NFE2L2 protein]; Thioctic Acid inhibits the reaction [Aldosterone results in increased activity of NFE2L2 protein]; W 7 inhibits the reaction [Aldosterone results in increased activity of NFE2L2 protein] CTD PMID:24512358 NCBI chr15:82,967,485...83,146,185
Ensembl chr15:82,973,648...83,146,183
JBrowse link
G SOD1 superoxide dismutase 1 increases expression EXP Aldosterone results in increased expression of SOD1 protein CTD PMID:24512358 NCBI chr13:195,326,573...195,335,273
Ensembl chr13:195,326,649...195,337,749
JBrowse link
G TXNRD1 thioredoxin reductase 1 increases expression EXP Aldosterone results in increased expression of TXNRD1 protein CTD PMID:24512358 NCBI chr 5:80,170,334...80,213,889
Ensembl chr 5:80,168,523...80,288,075
JBrowse link
betamethasone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HMOX2 heme oxygenase 2 increases expression EXP Betamethasone results in increased expression of HMOX2 protein CTD PMID:11698254 NCBI chr 3:37,829,044...37,868,163
Ensembl chr 3:37,831,434...37,868,128
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 decreases expression EXP Betamethasone results in decreased expression of PTGS2 protein CTD PMID:11698254 NCBI chr 9:127,850,164...127,858,866
Ensembl chr 9:127,850,013...127,858,884
JBrowse link
chlortetracycline term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLCO1A2 solute carrier organic anion transporter family member 1A2 multiple interactions
increases uptake
EXP Chlortetracycline inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; daidzein inhibits the reaction [SLCO1A2 protein results in increased uptake of Chlortetracycline]; epigallocatechin gallate inhibits the reaction [SLCO1A2 protein results in increased uptake of Chlortetracycline]; Genistein inhibits the reaction [SLCO1A2 protein results in increased uptake of Chlortetracycline]; naringin inhibits the reaction [SLCO1A2 protein results in increased uptake of Chlortetracycline]; Oxytetracycline inhibits the reaction [SLCO1A2 protein results in increased uptake of Chlortetracycline] CTD PMID:31287969 NCBI chr 5:52,020,303...52,133,132
Ensembl chr 5:52,037,218...52,131,789
JBrowse link
cortisol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGT angiotensinogen multiple interactions
increases secretion
EXP D-Ala(2),MePhe(4),Met(0)-ol-enkephalin promotes the reaction [AGT protein results in increased secretion of Hydrocortisone] CTD PMID:22100847 NCBI chr14:59,643,030...59,656,835
Ensembl chr14:59,643,292...59,672,428
JBrowse link
G POMC proopiomelanocortin multiple interactions
increases abundance
increases secretion
EXP Ditiocarb promotes the reaction [Sodium Selenite inhibits the reaction [POMC protein results in increased secretion of Hydrocortisone]]; Sodium Selenite inhibits the reaction [POMC protein results in increased secretion of Hydrocortisone]
POMC protein alternative form results in increased abundance of Hydrocortisone
CTD PMID:1666317, PMID:21466817, PMID:22100847 NCBI chr 3:113,661,712...113,668,558 JBrowse link
deoxynivalenol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTB actin beta increases expression EXP deoxynivalenol results in increased expression of ACTB mRNA CTD PMID:26417708 NCBI chr 3:4,084,275...4,090,383
Ensembl chr 3:4,082,216...4,090,356
JBrowse link
G AKT1 AKT serine/threonine kinase 1 decreases expression
decreases phosphorylation
EXP deoxynivalenol results in decreased expression of AKT1 mRNA; deoxynivalenol results in decreased expression of AKT1 protein
deoxynivalenol results in decreased phosphorylation of AKT1 protein
CTD PMID:16099139, PMID:32229166
G ALB albumin decreases expression EXP deoxynivalenol results in decreased expression of ALB protein CTD PMID:19477247 NCBI chr 8:69,643,427...69,663,152
Ensembl chr 8:69,531,487...69,718,304
JBrowse link
G AXIN2 axin 2 increases expression EXP deoxynivalenol results in increased expression of AXIN2 protein CTD PMID:30690062 NCBI chr12:12,311,293...12,343,207
Ensembl chr12:12,311,293...12,343,200
JBrowse link
G BCL2 BCL2 apoptosis regulator decreases expression
multiple interactions
EXP deoxynivalenol results in decreased expression of BCL2 mRNA; deoxynivalenol results in decreased expression of BCL2 protein
[Acetylcysteine co-treated with fumonisin B1 co-treated with deoxynivalenol] results in increased expression of BCL2 protein; [Acetylcysteine co-treated with Zearalenone co-treated with deoxynivalenol] results in increased expression of BCL2 protein; [fumonisin B1 co-treated with deoxynivalenol] results in decreased expression of BCL2 mRNA; [fumonisin B1 co-treated with Zearalenone co-treated with deoxynivalenol] results in decreased expression of BCL2 protein; Acetylcysteine inhibits the reaction [[fumonisin B1 co-treated with deoxynivalenol] results in decreased expression of BCL2 mRNA]; Acetylcysteine inhibits the reaction [deoxynivalenol results in decreased expression of BCL2 protein]; fumonisin B1 inhibits the reaction [deoxynivalenol results in decreased expression of BCL2 protein]; fumonisin B1 inhibits the reaction [Zearalenone inhibits the reaction [deoxynivalenol results in decreased expression of BCL2 mRNA]]; Zearalenone inhibits the reaction [deoxynivalenol results in decreased expression of BCL2 mRNA]; Zearalenone inhibits the reaction [fumonisin B1 inhibits the reaction [deoxynivalenol results in decreased expression of BCL2 protein]]
CTD PMID:25701311, PMID:29109043 NCBI chr 1:158,337,403...158,518,214
Ensembl chr 1:158,288,544...158,518,879
JBrowse link
G BMI1 BMI1 proto-oncogene, polycomb ring finger decreases expression EXP deoxynivalenol results in decreased expression of BMI1 protein CTD PMID:30690062 NCBI chr10:52,586,089...52,596,154 JBrowse link
G CASP3 caspase 3 multiple interactions
increases expression
increases activity
EXP [fumonisin B1 co-treated with deoxynivalenol] results in increased expression of CASP3 mRNA; [fumonisin B1 co-treated with deoxynivalenol] results in increased expression of CASP3 protein; [fumonisin B1 co-treated with Zearalenone] promotes the reaction [deoxynivalenol results in increased expression of CASP3 protein]; Acetylcysteine inhibits the reaction [[fumonisin B1 co-treated with Zearalenone] promotes the reaction [deoxynivalenol results in increased expression of CASP3 protein]]; Acetylcysteine inhibits the reaction [deoxynivalenol promotes the reaction [[fumonisin B1 co-treated with Zearalenone] results in increased expression of CASP3 mRNA]]; Acetylcysteine inhibits the reaction [deoxynivalenol promotes the reaction [Zearalenone results in increased expression of CASP3 mRNA]]; Acetylcysteine inhibits the reaction [deoxynivalenol results in increased expression of CASP3 protein]; Acetylcysteine inhibits the reaction [Zearalenone promotes the reaction [[fumonisin B1 co-treated with deoxynivalenol] results in increased expression of CASP3 mRNA]]; Acetylcysteine inhibits the reaction [Zearalenone promotes the reaction [deoxynivalenol results in increased expression of CASP3 mRNA]]; Acetylcysteine inhibits the reaction [Zearalenone promotes the reaction [deoxynivalenol results in increased expression of CASP3 protein]]; deoxynivalenol promotes the reaction [[fumonisin B1 co-treated with Zearalenone] results in increased expression of CASP3 mRNA]; deoxynivalenol promotes the reaction [Zearalenone results in increased expression of CASP3 mRNA]; fumonisin B1 promotes the reaction [deoxynivalenol promotes the reaction [Zearalenone results in increased expression of CASP3 mRNA]]; fumonisin B1 promotes the reaction [Zearalenone promotes the reaction [deoxynivalenol results in increased expression of CASP3 mRNA]]; Zearalenone promotes the reaction [[fumonisin B1 co-treated with deoxynivalenol] results in increased expression of CASP3 mRNA]; Zearalenone promotes the reaction [deoxynivalenol results in increased expression of CASP3 mRNA]; Zearalenone promotes the reaction [deoxynivalenol results in increased expression of CASP3 protein]
deoxynivalenol results in increased expression of CASP3 mRNA; deoxynivalenol results in increased expression of CASP3 protein
deoxynivalenol results in increased activity of CASP3 protein
CTD PMID:20937367, PMID:24394488, PMID:29109043 NCBI chr15:45,744,320...45,753,252
Ensembl chr15:45,742,749...45,763,773
JBrowse link
G CCL2 chemokine (C-C motif) ligand 2 increases expression
multiple interactions
decreases expression
EXP deoxynivalenol results in increased expression of CCL2 mRNA
[deoxynivalenol co-treated with fumonisin B1] results in increased expression of CCL2 mRNA; [deoxynivalenol co-treated with Lipopolysaccharides] results in increased expression of CCL2 mRNA; [deoxynivalenol co-treated with nivalenol co-treated with fumonisin B1] results in increased expression of CCL2 mRNA; [deoxynivalenol co-treated with nivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of CCL2 mRNA; [deoxynivalenol co-treated with nivalenol co-treated with Zearalenone] results in increased expression of CCL2 mRNA; [deoxynivalenol co-treated with nivalenol] results in increased expression of CCL2 mRNA; [deoxynivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of CCL2 mRNA; [deoxynivalenol co-treated with Zearalenone] results in increased expression of CCL2 mRNA; fumonisin B1 metabolite inhibits the reaction [[deoxynivalenol co-treated with Lipopolysaccharides] results in increased expression of CCL2 mRNA]; fumonisin B1 promotes the reaction [[deoxynivalenol co-treated with Lipopolysaccharides] results in increased expression of CCL2 mRNA]
deoxynivalenol results in decreased expression of CCL2 mRNA
CTD PMID:23688591, PMID:30708112 NCBI chr12:40,798,109...40,800,013
Ensembl chr12:40,798,109...40,800,028
JBrowse link
G CCL20 C-C motif chemokine ligand 20 multiple interactions
increases expression
EXP [deoxynivalenol co-treated with Lipopolysaccharides] results in increased expression of CCL20 mRNA; fumonisin B1 metabolite inhibits the reaction [[deoxynivalenol co-treated with Lipopolysaccharides] results in increased expression of CCL20 mRNA]; fumonisin B1 promotes the reaction [[deoxynivalenol co-treated with Lipopolysaccharides] results in increased expression of CCL20 mRNA]
deoxynivalenol results in increased expression of CCL20 mRNA
CTD PMID:23326479, PMID:30708112 NCBI chr15:129,172,743...129,176,069 JBrowse link
G CCND1 cyclin D1 decreases expression EXP deoxynivalenol results in decreased expression of CCND1 protein CTD PMID:30690062 NCBI chr 2:3,621,242...3,633,380
Ensembl chr 2:3,621,246...3,633,296
JBrowse link
G CCR6 C-C motif chemokine receptor 6 increases expression EXP deoxynivalenol results in increased expression of CCR6 mRNA CTD PMID:23326479 NCBI chr 1:2,016,600...2,034,172
Ensembl chr 1:2,018,608...2,019,821
JBrowse link
G CLDN3 claudin 3 decreases expression EXP deoxynivalenol analog results in decreased expression of CLDN3 protein; deoxynivalenol results in decreased expression of CLDN3 protein CTD PMID:19289138, PMID:22859312 NCBI chr 3:11,019,073...11,020,102
Ensembl chr 3:11,019,295...11,019,960
JBrowse link
G CLDN4 claudin 4 decreases expression EXP deoxynivalenol analog results in decreased expression of CLDN4 protein; deoxynivalenol results in decreased expression of CLDN4 protein CTD PMID:19289138, PMID:22859312 NCBI chr 3:11,039,711...11,053,930
Ensembl chr 3:11,039,706...11,053,925
JBrowse link
G CRP C-reactive protein, pentraxin-related decreases expression EXP deoxynivalenol results in decreased expression of CRP protein CTD PMID:25701311 NCBI chr 4:90,793,361...90,801,020
Ensembl chr 4:90,722,352...90,805,236
JBrowse link
G CTNNB1 catenin beta 1 decreases expression EXP deoxynivalenol results in decreased expression of CTNNB1 protein CTD PMID:30690062 NCBI chr13:25,163,550...25,208,314
Ensembl chr13:25,137,173...25,208,311
JBrowse link
G CX3CL1 C-X3-C motif chemokine ligand 1 increases expression EXP deoxynivalenol results in increased expression of CX3CL1 mRNA CTD PMID:23326479 NCBI chr 6:19,312,351...19,324,439 JBrowse link
G CXCL10 C-X-C motif chemokine ligand 10 increases expression EXP deoxynivalenol results in increased expression of CXCL10 mRNA CTD PMID:25701311 NCBI chr 8:71,693,641...71,695,948
Ensembl chr 8:71,693,339...71,695,948
JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 increases expression
decreases expression
multiple interactions
EXP deoxynivalenol results in increased expression of CXCL8 mRNA; deoxynivalenol results in increased expression of CXCL8 protein
deoxynivalenol results in decreased expression of CXCL8 protein
[deoxynivalenol co-treated with fumonisin B1] results in increased expression of CXCL8 mRNA; [deoxynivalenol co-treated with Lipopolysaccharides] results in increased expression of CXCL8 mRNA; [deoxynivalenol co-treated with nivalenol co-treated with fumonisin B1] results in increased expression of CXCL8 mRNA; [deoxynivalenol co-treated with nivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of CXCL8 mRNA; [deoxynivalenol co-treated with nivalenol co-treated with Zearalenone] results in increased expression of CXCL8 mRNA; [deoxynivalenol co-treated with nivalenol] results in increased expression of CXCL8 mRNA; [deoxynivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of CXCL8 mRNA; [deoxynivalenol co-treated with Zearalenone] results in increased expression of CXCL8 mRNA; deoxynivalenol promotes the reaction [nivalenol results in increased expression of CXCL8 mRNA]; fumonisin B1 metabolite inhibits the reaction [[deoxynivalenol co-treated with Lipopolysaccharides] results in increased expression of CXCL8 mRNA]; fumonisin B1 promotes the reaction [[deoxynivalenol co-treated with Lipopolysaccharides] results in increased expression of CXCL8 mRNA]
CTD PMID:23326479, PMID:23688591, PMID:25701311, PMID:26417708, PMID:27915442, PMID:30708112 NCBI chr 8:69,932,646...69,935,861
Ensembl chr 8:69,932,643...69,935,861
JBrowse link
G CYCS cytochrome c, somatic multiple interactions EXP [deoxynivalenol co-treated with fumonisin B1] results in increased expression of CYCS mRNA; Acetylcysteine inhibits the reaction [deoxynivalenol promotes the reaction [[Zearalenone co-treated with fumonisin B1] results in increased expression of CYCS mRNA]]; Acetylcysteine inhibits the reaction [deoxynivalenol promotes the reaction [Zearalenone results in increased expression of CYCS mRNA]]; Acetylcysteine inhibits the reaction [fumonisin B1 promotes the reaction [deoxynivalenol promotes the reaction [Zearalenone results in increased expression of CYCS mRNA]]]; Acetylcysteine inhibits the reaction [Zearalenone promotes the reaction [[deoxynivalenol co-treated with fumonisin B1] results in increased expression of CYCS mRNA]]; deoxynivalenol promotes the reaction [[Zearalenone co-treated with fumonisin B1] results in increased expression of CYCS mRNA]; deoxynivalenol promotes the reaction [Zearalenone results in increased expression of CYCS mRNA]; fumonisin B1 promotes the reaction [deoxynivalenol promotes the reaction [Zearalenone results in increased expression of CYCS mRNA]]; Zearalenone promotes the reaction [[deoxynivalenol co-treated with fumonisin B1] results in increased expression of CYCS mRNA] CTD PMID:29109043 NCBI chr18:47,169,921...47,172,212
Ensembl chr18:47,169,866...47,173,866
JBrowse link
G CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1 multiple interactions EXP deoxynivalenol inhibits the reaction [[FSHB protein co-treated with IGF1 protein] results in increased expression of CYP11A1 mRNA] CTD PMID:17656051 NCBI chr 7:59,172,829...59,188,479
Ensembl chr 7:59,175,758...59,188,478
JBrowse link
G CYP19A2 cytochrome P450 19A2 multiple interactions EXP deoxynivalenol inhibits the reaction [[FSHB protein co-treated with IGF1 protein] results in increased expression of CYP19A1 mRNA] CTD PMID:17656051 NCBI chr 1:120,652,172...120,695,899
Ensembl chr 1:120,367,667...120,695,899
JBrowse link
G DEFB1 defensin beta 1 decreases expression EXP deoxynivalenol results in decreased expression of DEFB1 mRNA CTD PMID:25701311
G DNMT3A DNA methyltransferase 3 alpha increases expression EXP deoxynivalenol results in increased expression of DNMT3A mRNA CTD PMID:26988607 NCBI chr 3:113,501,972...113,609,148
Ensembl chr 3:113,528,926...113,609,139
JBrowse link
G EIF4E eukaryotic translation initiation factor 4E decreases phosphorylation EXP deoxynivalenol results in decreased phosphorylation of EIF4E protein CTD PMID:16099139 NCBI chr 8:121,409,633...121,464,467
Ensembl chr 8:121,409,731...121,466,899
JBrowse link
G EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 decreases expression EXP deoxynivalenol results in decreased expression of EIF4EBP1 protein modified form CTD PMID:16099139 NCBI chr15:48,423,001...48,443,373
Ensembl chr15:48,422,816...48,443,399
JBrowse link
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit increases expression EXP deoxynivalenol results in increased expression of EZH2 mRNA CTD PMID:26988607 NCBI chr 9:109,384,976...109,450,943
Ensembl chr 9:109,384,995...109,450,941
JBrowse link
G FSHB follicle stimulating hormone subunit beta multiple interactions EXP deoxynivalenol affects the reaction [[FSHB protein co-treated with IGF1 protein] results in increased abundance of Estradiol]; deoxynivalenol inhibits the reaction [[FSHB protein co-treated with IGF1 protein] results in increased abundance of Progesterone]; deoxynivalenol inhibits the reaction [[FSHB protein co-treated with IGF1 protein] results in increased expression of CYP11A1 mRNA]; deoxynivalenol inhibits the reaction [[FSHB protein co-treated with IGF1 protein] results in increased expression of CYP19A1 mRNA] CTD PMID:17656051 NCBI chr 2:30,395,769...30,399,282
Ensembl chr 2:30,395,018...30,399,274
JBrowse link
G GPX2 glutathione peroxidase 2 increases expression EXP deoxynivalenol results in increased expression of GPX2 mRNA CTD PMID:25701311 NCBI chr 7:89,007,636...89,011,620
Ensembl chr 7:89,007,369...89,011,620
JBrowse link
G GPX3 glutathione peroxidase 3 decreases expression EXP deoxynivalenol results in decreased expression of GPX3 mRNA CTD PMID:25701311 NCBI chr16:71,980,467...71,989,011
Ensembl chr16:71,980,475...71,989,026
JBrowse link
G GPX4 glutathione peroxidase 4 decreases expression EXP deoxynivalenol results in decreased expression of GPX4 mRNA CTD PMID:25701311 NCBI chr 2:77,321,568...77,323,931
Ensembl chr 2:77,320,464...77,323,886
JBrowse link
G GSK3B glycogen synthase kinase 3 beta increases expression EXP deoxynivalenol results in increased expression of GSK3B protein CTD PMID:30690062 NCBI chr13:140,136,109...140,370,197
Ensembl chr13:140,136,158...140,369,574
JBrowse link
G GSR glutathione-disulfide reductase decreases activity
multiple interactions
EXP deoxynivalenol results in decreased activity of GSR protein
Acetylcysteine inhibits the reaction [fumonisin B1 promotes the reaction [deoxynivalenol results in decreased activity of GSR protein]]; Acetylcysteine inhibits the reaction [fumonisin B1 promotes the reaction [Zearalenone promotes the reaction [deoxynivalenol results in decreased activity of GSR protein]]]; Acetylcysteine inhibits the reaction [Zearalenone promotes the reaction [fumonisin B1 promotes the reaction [deoxynivalenol results in decreased activity of GSR protein]]]; fumonisin B1 promotes the reaction [deoxynivalenol results in decreased activity of GSR protein]; fumonisin B1 promotes the reaction [Zearalenone promotes the reaction [deoxynivalenol results in decreased activity of GSR protein]]; Zearalenone promotes the reaction [deoxynivalenol results in decreased activity of GSR protein]; Zearalenone promotes the reaction [fumonisin B1 promotes the reaction [deoxynivalenol results in decreased activity of GSR protein]]
CTD PMID:29109043 NCBI chr15:54,382,564...54,433,989
Ensembl chr15:54,382,567...54,433,989
JBrowse link
G IFNB1 interferon beta 1 increases expression EXP deoxynivalenol results in increased expression of IFNB1 mRNA CTD PMID:24394488 NCBI chr 1:201,850,935...201,851,495
Ensembl chr 1:201,850,935...201,851,495
JBrowse link
G IFNG interferon gamma increases expression
decreases expression
multiple interactions
EXP deoxynivalenol results in increased expression of IFNG mRNA
deoxynivalenol results in decreased expression of IFNG mRNA
[Zearalenone co-treated with deoxynivalenol] results in decreased expression of IFNG mRNA
CTD PMID:18296887, PMID:18329193, PMID:25701311 NCBI chr 5:32,477,906...32,482,670
Ensembl chr 5:32,477,848...32,482,752
JBrowse link
G IGF1 insulin like growth factor 1 multiple interactions EXP deoxynivalenol affects the reaction [[FSHB protein co-treated with IGF1 protein] results in increased abundance of Estradiol]; deoxynivalenol affects the reaction [IGF1 protein results in increased abundance of Estradiol]; deoxynivalenol inhibits the reaction [[FSHB protein co-treated with IGF1 protein] results in increased abundance of Progesterone]; deoxynivalenol inhibits the reaction [[FSHB protein co-treated with IGF1 protein] results in increased expression of CYP11A1 mRNA]; deoxynivalenol inhibits the reaction [[FSHB protein co-treated with IGF1 protein] results in increased expression of CYP19A1 mRNA] CTD PMID:17656051 NCBI chr 5:81,762,027...81,909,253
Ensembl chr 5:81,775,970...81,848,037
JBrowse link
G IL10 interleukin 10 increases expression
multiple interactions
EXP deoxynivalenol results in increased expression of IL10 mRNA
deoxynivalenol promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL10 mRNA]
CTD PMID:19027837, PMID:19607891 NCBI chr 9:67,400,727...67,405,941
Ensembl chr 9:67,400,727...67,405,711
JBrowse link
G IL17A interleukin 17A multiple interactions
increases expression
EXP [deoxynivalenol co-treated with Lipopolysaccharides] results in increased expression of IL17A protein; deoxynivalenol promotes the reaction [nivalenol results in increased expression of IL17A mRNA]; fumonisin B1 inhibits the reaction [[deoxynivalenol co-treated with Lipopolysaccharides] results in increased expression of IL17A protein]; fumonisin B1 metabolite inhibits the reaction [[deoxynivalenol co-treated with Lipopolysaccharides] results in increased expression of IL17A protein]
deoxynivalenol results in increased expression of IL17A mRNA; deoxynivalenol results in increased expression of IL17A protein
CTD PMID:23326479, PMID:27915442, PMID:30708112 NCBI chr 7:46,013,584...46,017,161
Ensembl chr 7:46,013,584...46,017,153
JBrowse link
G IL1A interleukin 1 alpha increases expression
multiple interactions
decreases expression
EXP deoxynivalenol results in increased expression of IL1A mRNA; deoxynivalenol results in increased expression of IL1A protein
[deoxynivalenol co-treated with fumonisin B1] results in decreased expression of IL1A mRNA; [deoxynivalenol co-treated with nivalenol co-treated with fumonisin B1] results in increased expression of IL1A mRNA; [deoxynivalenol co-treated with nivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of IL1A mRNA; [deoxynivalenol co-treated with nivalenol co-treated with Zearalenone] results in increased expression of IL1A mRNA; [deoxynivalenol co-treated with nivalenol] results in increased expression of IL1A mRNA; [deoxynivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of IL1A mRNA; [deoxynivalenol co-treated with Zearalenone] results in decreased expression of IL1A mRNA; [deoxynivalenol co-treated with Zearalenone] results in increased expression of IL1A mRNA; deoxynivalenol promotes the reaction [nivalenol results in increased expression of IL1A mRNA]; nivalenol promotes the reaction [deoxynivalenol results in increased expression of IL1A mRNA]
deoxynivalenol results in decreased expression of IL1A mRNA
CTD PMID:23326479, PMID:23688591, PMID:27915442 NCBI chr 3:43,718,320...43,731,668
Ensembl chr 3:43,718,368...43,731,119
JBrowse link
G IL1B2 interleukin 1, beta 2 increases expression
multiple interactions
EXP deoxynivalenol results in increased expression of IL1B2 mRNA
deoxynivalenol promotes the reaction [nivalenol results in increased expression of IL1B2 mRNA]; nivalenol promotes the reaction [deoxynivalenol results in increased expression of IL1B2 mRNA]
CTD PMID:27915442
G IL2 interleukin 2 multiple interactions EXP [Zearalenone co-treated with deoxynivalenol] results in decreased expression of IL2 mRNA CTD PMID:18296887 NCBI chr 8:101,640,938...101,645,683
Ensembl chr 8:101,640,944...101,645,609
JBrowse link
G IL21 interleukin 21 increases expression EXP deoxynivalenol results in increased expression of IL21 mRNA CTD PMID:23326479 NCBI chr 8:101,532,742...101,540,712
Ensembl chr 8:101,530,949...101,540,738
JBrowse link
G IL22 interleukin 22 multiple interactions
increases expression
EXP deoxynivalenol promotes the reaction [nivalenol results in increased expression of IL22 mRNA]
deoxynivalenol results in increased expression of IL22 mRNA
CTD PMID:23326479, PMID:27915442 NCBI chr 5:32,599,522...32,604,507
Ensembl chr 5:32,599,301...32,604,736
JBrowse link
G IL23A interleukin 23 subunit alpha increases expression EXP deoxynivalenol results in increased expression of IL23A mRNA CTD PMID:23326479 NCBI chr 5:21,732,416...21,733,981
Ensembl chr 5:21,732,165...21,734,267
JBrowse link
G IL4 interleukin 4 increases expression EXP deoxynivalenol results in increased expression of IL4 mRNA CTD PMID:25701311 NCBI chr 2:134,986,817...134,994,365
Ensembl chr 2:134,986,817...134,994,365
JBrowse link
G IL6 interleukin 6 multiple interactions
increases expression
EXP [deoxynivalenol co-treated with fumonisin B1] results in increased expression of IL6 mRNA; [deoxynivalenol co-treated with nivalenol co-treated with fumonisin B1] results in increased expression of IL6 mRNA; [deoxynivalenol co-treated with nivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of IL6 mRNA; [deoxynivalenol co-treated with nivalenol co-treated with Zearalenone] results in increased expression of IL6 mRNA; [deoxynivalenol co-treated with nivalenol] results in decreased expression of IL6 mRNA; [deoxynivalenol co-treated with nivalenol] results in increased expression of IL6 mRNA; [deoxynivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of IL6 mRNA; [deoxynivalenol co-treated with Zearalenone] results in increased expression of IL6 mRNA; deoxynivalenol affects the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL6 mRNA]; deoxynivalenol affects the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL6 protein]
deoxynivalenol results in increased expression of IL6 mRNA; deoxynivalenol results in increased expression of IL6 protein
CTD PMID:19027837, PMID:19607891, PMID:23326479, PMID:23688591, PMID:24394488 NCBI chr 9:91,506,421...91,510,830
Ensembl chr 9:91,506,340...91,511,263
JBrowse link
G LAMP2 lysosomal associated membrane protein 2 increases expression EXP deoxynivalenol results in increased expression of LAMP2 mRNA CTD PMID:26988607 NCBI chr  X:98,586,718...98,623,939
Ensembl chr  X:98,582,059...98,623,908
JBrowse link
G LOC110258578 interleukin-1 beta-like multiple interactions
increases expression
EXP [deoxynivalenol co-treated with fumonisin B1] results in increased expression of IL1B mRNA; [deoxynivalenol co-treated with nivalenol co-treated with fumonisin B1] results in increased expression of IL1B mRNA; [deoxynivalenol co-treated with nivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of IL1B mRNA; [deoxynivalenol co-treated with nivalenol co-treated with Zearalenone] results in increased expression of IL1B mRNA; [deoxynivalenol co-treated with nivalenol] results in increased expression of IL1B mRNA; [deoxynivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of IL1B mRNA; [deoxynivalenol co-treated with Zearalenone] results in increased expression of IL1B mRNA; deoxynivalenol promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL1B mRNA]
deoxynivalenol results in increased expression of IL1B mRNA
CTD PMID:19027837, PMID:23326479, PMID:23688591
G MAP1LC3A microtubule associated protein 1 light chain 3 alpha increases expression EXP deoxynivalenol results in increased expression of MAP1LC3A mRNA CTD PMID:32229166, PMID:32302720 NCBI chr17:37,957,830...37,959,505
Ensembl chr17:37,957,507...37,959,505
JBrowse link
G MAP1LC3B microtubule associated protein 1 light chain 3 beta increases expression EXP deoxynivalenol results in increased expression of MAP1LC3B mRNA CTD PMID:26988607 NCBI chr 6:1,919,879...1,941,069
Ensembl chr 6:1,915,387...1,941,077
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 increases phosphorylation
decreases expression
increases activity
EXP deoxynivalenol analog results in increased phosphorylation of MAPK1 protein; deoxynivalenol results in increased phosphorylation of MAPK1 protein
deoxynivalenol results in decreased expression of MAPK1 protein modified form
deoxynivalenol results in increased activity of MAPK1 protein
CTD PMID:19674540, PMID:22859312, PMID:26988607 NCBI chr14:50,083,079...50,165,528
Ensembl chr14:50,082,896...50,165,523
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 decreases expression
increases activity
increases phosphorylation
EXP deoxynivalenol results in decreased expression of MAPK3 protein modified form
deoxynivalenol results in increased activity of MAPK3 protein
deoxynivalenol analog results in increased phosphorylation of MAPK3 protein; deoxynivalenol results in increased phosphorylation of MAPK3 protein
CTD PMID:19674540, PMID:22859312, PMID:26988607 NCBI chr 3:18,291,444...18,299,410
Ensembl chr 3:18,291,445...18,299,567
JBrowse link
G MFN1 mitofusin 1 decreases expression EXP deoxynivalenol results in decreased expression of MFN1 protein CTD PMID:32302720 NCBI chr13:117,404,637...117,441,750
Ensembl chr13:117,404,699...117,442,481
JBrowse link
G MFN2 mitofusin 2 decreases expression EXP deoxynivalenol results in decreased expression of MFN2 protein CTD PMID:32302720 NCBI chr 6:72,026,512...72,056,439
Ensembl chr 6:72,026,722...72,056,439
JBrowse link
G MTOR mechanistic target of rapamycin kinase decreases expression
decreases phosphorylation
EXP deoxynivalenol results in decreased expression of MTOR mRNA
deoxynivalenol results in decreased phosphorylation of MTOR protein
CTD PMID:26988607, PMID:32229166 NCBI chr 6:71,286,989...71,412,913
Ensembl chr 6:71,286,989...71,412,888
JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor decreases expression EXP deoxynivalenol results in decreased expression of MYC protein CTD PMID:30690062 NCBI chr 4:12,455,141...12,460,360
Ensembl chr 4:12,455,119...12,461,078
JBrowse link
G NOS2 nitric oxide synthase 2 increases expression EXP deoxynivalenol results in increased expression of NOS2 mRNA CTD PMID:25701311 NCBI chr12:44,174,944...44,219,875
Ensembl chr12:44,174,944...44,327,111
JBrowse link
G OCLN occludin decreases expression EXP deoxynivalenol results in decreased expression of OCLN mRNA CTD PMID:25701311 NCBI chr16:47,600,175...47,652,435
Ensembl chr16:47,600,498...47,654,033
JBrowse link
G OPA1 OPA1 mitochondrial dynamin like GTPase decreases expression EXP deoxynivalenol results in decreased expression of OPA1 protein CTD PMID:32302720 NCBI chr13:130,624,771...130,718,345
Ensembl chr13:130,624,823...130,719,083
JBrowse link
G PCNA proliferating cell nuclear antigen decreases expression EXP deoxynivalenol results in decreased expression of PCNA protein CTD PMID:30690062 NCBI chr17:14,137,746...14,142,584
Ensembl chr17:14,125,814...14,185,276
JBrowse link
G PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma decreases expression EXP deoxynivalenol results in decreased expression of PIK3CG mRNA CTD PMID:32229166 NCBI chr 9:106,698,200...106,748,217
Ensembl chr 9:106,698,207...106,745,099
JBrowse link
G RPS6KB1 ribosomal protein S6 kinase B1 decreases expression
decreases phosphorylation
EXP deoxynivalenol results in decreased expression of RPS6KB1 mRNA
deoxynivalenol results in decreased phosphorylation of RPS6KB1 protein
CTD PMID:32229166 NCBI chr12:36,111,584...36,159,287 JBrowse link
G SETDB1 SET domain bifurcated histone lysine methyltransferase 1 increases expression EXP deoxynivalenol results in increased expression of SETDB1 mRNA CTD PMID:26988607 NCBI chr 4:98,259,801...98,293,238
Ensembl chr 4:98,260,373...98,293,096
JBrowse link
G SQSTM1 sequestosome 1 increases expression EXP deoxynivalenol results in increased expression of SQSTM1 mRNA CTD PMID:32302720 NCBI chr 2:78,752,768...78,763,998
Ensembl chr 2:78,752,768...78,784,256
JBrowse link
G STAT3 signal transducer and activator of transcription 3 increases expression EXP deoxynivalenol results in increased expression of STAT3 mRNA CTD PMID:23326479 NCBI chr12:20,407,316...20,471,091
Ensembl chr12:20,407,233...20,472,993
JBrowse link
G SUV39H2 suppressor of variegation 3-9 homolog 2 increases expression EXP deoxynivalenol results in increased expression of SUV39H2 mRNA CTD PMID:26988607 NCBI chr10:46,874,606...46,900,058
Ensembl chr10:46,862,584...46,900,040
JBrowse link
G TFF1 trefoil factor 1 affects expression EXP deoxynivalenol affects the expression of TFF1 mRNA CTD PMID:30854615 NCBI chr13:205,687,558...205,691,512 JBrowse link
G TFF2 trefoil factor 2 decreases expression EXP deoxynivalenol results in decreased expression of TFF2 mRNA CTD PMID:30854615 NCBI chr13:205,669,014...205,672,319
Ensembl chr13:205,669,014...205,672,324
JBrowse link
G TFF3 trefoil factor 3 decreases expression EXP deoxynivalenol results in decreased expression of TFF3 mRNA CTD PMID:30854615 NCBI chr13:205,641,038...205,644,333
Ensembl chr13:205,642,374...205,644,334
JBrowse link
G TGFB1 transforming growth factor beta 1 decreases expression
increases expression
EXP deoxynivalenol results in decreased expression of TGFB1 mRNA
deoxynivalenol results in increased expression of TGFB1 mRNA
CTD PMID:18329193, PMID:23326479 NCBI chr 6:49,332,169...49,348,642
Ensembl chr 6:49,332,169...49,349,048
JBrowse link
G TJP1 tight junction protein 1 increases expression
decreases expression
EXP deoxynivalenol results in increased expression of TJP1 mRNA
deoxynivalenol results in decreased expression of TJP1 protein
CTD PMID:20937367, PMID:26417708 NCBI chr 1:144,930,387...145,195,857
Ensembl chr 1:144,930,368...145,195,836
JBrowse link
G TNF tumor necrosis factor multiple interactions
increases expression
EXP [deoxynivalenol co-treated with fumonisin B1] results in increased expression of TNF mRNA; [deoxynivalenol co-treated with Lipopolysaccharides co-treated with fumonisin B1] results in increased expression of TNF mRNA; [deoxynivalenol co-treated with Lipopolysaccharides co-treated with fumonisin B1] results in increased expression of TNF protein; [deoxynivalenol co-treated with nivalenol co-treated with fumonisin B1] results in increased expression of TNF mRNA; [deoxynivalenol co-treated with nivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of TNF mRNA; [deoxynivalenol co-treated with nivalenol co-treated with Zearalenone] results in increased expression of TNF mRNA; [deoxynivalenol co-treated with nivalenol] results in increased expression of TNF mRNA; [deoxynivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of TNF mRNA; [deoxynivalenol co-treated with Zearalenone] results in increased expression of TNF mRNA; [Zearalenone co-treated with deoxynivalenol] results in decreased expression of TNF mRNA; deoxynivalenol promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TNF mRNA]; deoxynivalenol promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TNF protein]; lipopolysaccharide, Escherichia coli O111 B4 promotes the reaction [deoxynivalenol results in increased expression of TNF mRNA] CTD PMID:18296887, PMID:19027837, PMID:19607891, PMID:23326479, PMID:23688591, PMID:24394488, PMID:30708112 NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,636...23,703,655
JBrowse link
G TP53 tumor protein p53 multiple interactions EXP [deoxynivalenol co-treated with fumonisin B1] results in increased expression of TP53 mRNA; Acetylcysteine promotes the reaction [deoxynivalenol inhibits the reaction [Zearalenone results in increased expression of TP53 mRNA]]; deoxynivalenol inhibits the reaction [Zearalenone results in increased expression of TP53 mRNA]; fumonisin B1 inhibits the reaction [deoxynivalenol inhibits the reaction [Zearalenone results in increased expression of TP53 mRNA]]; Zearalenone promotes the reaction [[deoxynivalenol co-treated with fumonisin B1] results in increased expression of TP53 mRNA] CTD PMID:29109043 NCBI chr12:52,939,643...52,953,786
Ensembl chr12:52,939,643...52,953,819
JBrowse link
G VIM vimentin decreases expression EXP deoxynivalenol results in decreased expression of VIM mRNA CTD PMID:25701311 NCBI chr10:43,516,441...43,526,172
Ensembl chr10:43,517,307...43,526,172
JBrowse link
G XCR1 X-C motif chemokine receptor 1 increases expression EXP deoxynivalenol results in increased expression of XCR1 mRNA CTD PMID:23326479 NCBI chr13:29,150,376...29,233,802
Ensembl chr13:29,150,379...29,159,637
JBrowse link
doxorubicin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HSPA1L heat shock protein family A (Hsp70) member 1 like increases expression EXP Doxorubicin results in increased expression of HSPA1A protein CTD PMID:15810080 NCBI chr 7:23,909,960...23,938,678
Ensembl chr 7:23,909,960...23,921,723
JBrowse link
G MMP1 matrix metallopeptidase 1 increases activity
increases expression
EXP Doxorubicin results in increased activity of MMP1 protein
Doxorubicin results in increased expression of MMP1 mRNA
CTD PMID:19782292 NCBI chr 9:33,411,738...33,420,205
Ensembl chr 9:33,411,065...33,454,000
JBrowse link
G MMP14 matrix metallopeptidase 14 increases expression
increases activity
EXP Doxorubicin results in increased expression of MMP14 mRNA
Doxorubicin results in increased activity of MMP14 protein
CTD PMID:19782292 NCBI chr 7:76,174,502...76,185,931
Ensembl chr 7:76,174,500...76,185,923
JBrowse link
G MMP2 matrix metallopeptidase 2 increases expression
increases activity
EXP Doxorubicin results in increased expression of MMP2 mRNA
Doxorubicin results in increased activity of MMP2 protein
CTD PMID:19782292 NCBI chr 6:30,059,247...30,087,031
Ensembl chr 6:30,058,594...30,086,982
JBrowse link
G MMP9 matrix metallopeptidase 9 increases expression
increases activity
EXP Doxorubicin results in increased expression of MMP9 mRNA
Doxorubicin results in increased activity of MMP9 protein
CTD PMID:19782292 NCBI chr17:48,179,690...48,186,782
Ensembl chr17:48,175,056...48,188,264
JBrowse link
G TNF tumor necrosis factor decreases expression EXP Doxorubicin results in decreased expression of TNF mRNA CTD PMID:15810080 NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,636...23,703,655
JBrowse link
phorbol 13-acetate 12-myristate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CXCL8 C-X-C motif chemokine ligand 8 multiple interactions EXP [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased secretion of CXCL8 protein CTD PMID:15912099 NCBI chr 8:69,932,646...69,935,861
Ensembl chr 8:69,932,643...69,935,861
JBrowse link
G EDN1 endothelin 1 multiple interactions
increases expression
EXP Clofibrate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of EDN1 protein] CTD PMID:17105827 NCBI chr 7:8,752,018...8,758,354
Ensembl chr 7:8,751,695...8,758,348
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 increases phosphorylation EXP Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein CTD PMID:11325585 NCBI chr14:50,083,079...50,165,528
Ensembl chr14:50,082,896...50,165,523
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 increases phosphorylation EXP Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein CTD PMID:11325585 NCBI chr 3:18,291,444...18,299,410
Ensembl chr 3:18,291,445...18,299,567
JBrowse link
G MAPK9 mitogen-activated protein kinase 9 increases phosphorylation EXP Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK9 protein CTD PMID:11325585 NCBI chr 2:78,338,466...78,399,108
Ensembl chr 2:78,338,369...78,399,105
JBrowse link
G PPARA peroxisome proliferator activated receptor alpha decreases expression
multiple interactions
EXP Tetradecanoylphorbol Acetate results in decreased expression of PPARA; Tetradecanoylphorbol Acetate results in decreased expression of PPARA protein
calphostin C promotes the reaction [Tetradecanoylphorbol Acetate results in decreased expression of PPARA]; Tetradecanoylphorbol Acetate inhibits the reaction [Clofibrate results in increased expression of PPARA]
CTD PMID:17105827, PMID:20568414 NCBI chr 5:3,302,755...3,321,091
Ensembl chr 5:3,300,708...3,366,361
JBrowse link
G PRKCB protein kinase C beta decreases phosphorylation EXP Tetradecanoylphorbol Acetate results in decreased phosphorylation of PRKCB protein CTD PMID:15089098 NCBI chr 3:21,995,227...22,383,628
Ensembl chr 3:21,995,231...22,383,264
JBrowse link
G PRKCD protein kinase C delta increases phosphorylation EXP Tetradecanoylphorbol Acetate results in increased phosphorylation of PRKCD protein CTD PMID:15089098 NCBI chr13:35,290,835...35,323,245
Ensembl chr13:35,290,264...35,323,356
JBrowse link
G SELE selectin E increases expression EXP Tetradecanoylphorbol Acetate results in increased expression of SELE protein CTD PMID:16797888 NCBI chr 4:81,289,061...81,299,657 JBrowse link
G SELP selectin P increases expression EXP Tetradecanoylphorbol Acetate results in increased expression of SELP protein CTD PMID:16797888 NCBI chr 4:81,376,804...81,401,240
Ensembl chr 4:81,365,740...81,406,203
JBrowse link
G VCAM1 vascular cell adhesion molecule 1 increases expression EXP Tetradecanoylphorbol Acetate results in increased expression of VCAM1 protein CTD PMID:16797888 NCBI chr 4:117,496,914...117,511,211
Ensembl chr 4:117,496,908...117,511,226
JBrowse link
tetracycline term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLCO1A2 solute carrier organic anion transporter family member 1A2 increases uptake
multiple interactions
EXP SLCO1A2 protein results in increased uptake of Tetracycline
Tetracycline inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; Tetracycline inhibits the reaction [SLCO1A2 protein results in increased uptake of Taurocholic Acid]
CTD PMID:31287969 NCBI chr 5:52,020,303...52,133,132
Ensembl chr 5:52,037,218...52,131,789
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 880
    chemical entity 880
      group 843
        inorganic group 698
          oxo group 388
            organic oxo compound 388
              carbonyl compound 388
                ketone 177
                  oxyketone 98
                    alpha-oxyketone 98
                      2-methoxyacetophenone 0
                      alpha-hydroxy ketone + 98
Path 2
Term Annotations click to browse term
  CHEBI ontology 880
    subatomic particle 865
      composite particle 865
        hadron 865
          baryon 865
            nucleon 865
              atomic nucleus 865
                atom 865
                  main group element atom 855
                    p-block element atom 852
                      carbon group element atom 827
                        carbon atom 826
                          organic molecular entity 826
                            organic group 391
                              organic divalent group 389
                                organodiyl group 389
                                  carbonyl group 388
                                    carbonyl compound 388
                                      ketone 177
                                        oxyketone 98
                                          alpha-oxyketone 98
                                            2-methoxyacetophenone 0
                                            alpha-hydroxy ketone + 98
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.