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ONTOLOGY REPORT - ANNOTATIONS


Term:2-arachidonoylglycerol
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Accession:CHEBI:52392 term browser browse the term
Definition:An endocannabinoid and an endogenous agonist of the cannabinoid receptors (CB1 and CB2). It is an ester formed from omega-6-arachidonic acid and glycerol.
Synonyms:exact_synonym: 1,3-dihydroxypropan-2-yl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate
 related_synonym: 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol;   2-AG;   2-Ara-Gl;   2-Arachidonoyl-glycerol;   2-Arachidonyl-glycerol;   Formula=C23H38O4;   InChI=1S/C23H38O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-23(26)27-22(20-24)21-25/h6-7,9-10,12-13,15-16,22,24-25H,2-5,8,11,14,17-21H2,1H3/b7-6-,10-9-,13-12-,16-15-;   InChIKey=RCRCTBLIHCHWDZ-DOFZRALJSA-N;   SMILES=[H]C(CO)(CO)OC(=O)CCC\\C=C/C\\C=C/C\\C=C/C\\C=C/CCCCC
 alt_id: CHEBI:34261;   CHEBI:52365
 xref: CAS:53847-30-6 "ChemIDplus";   CAS:53847-30-6 "KEGG COMPOUND";   HMDB:HMDB0004666;   KEGG:C13856;   LIPID_MAPS_instance:LMGL01010023 "LIPID MAPS"
 xref_mesh: MESH:C094503
 xref: MetaCyc:CPD-12600;   PMID:12878451 "Europe PMC";   PMID:15543349 "Europe PMC";   PMID:18771906 "Europe PMC";   Reaxys:8167264 "Reaxys";   Wikipedia:2-Arachidonoylglycerol


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2-arachidonoylglycerol term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abhd12 abhydrolase domain containing 12 JBrowse link 3 146,630,298 146,690,375 RGD:6480464
G Abhd6 abhydrolase domain containing 6 JBrowse link 15 18,647,903 18,695,133 RGD:6480464
G Acta2 actin alpha 2, smooth muscle JBrowse link 1 252,537,614 252,550,394 RGD:6480464
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:6480464
G Ces1d carboxylesterase 1D JBrowse link 19 15,195,514 15,239,827 RGD:6480464
G Ces2h carboxylesterase 2H JBrowse link 19 37,052,555 37,067,176 RGD:6480464
G Cnr1 cannabinoid receptor 1 JBrowse link 5 49,307,584 49,333,064 RGD:6480464
G Cnr2 cannabinoid receptor 2 JBrowse link 5 154,242,010 154,268,126 RGD:6480464
G Creb3l3 cAMP responsive element binding protein 3-like 3 JBrowse link 7 11,490,852 11,499,287 RGD:6480464
G Crh corticotropin releasing hormone JBrowse link 2 104,459,999 104,461,863 RGD:6480464
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 JBrowse link 9 81,968,285 81,998,213 RGD:6480464
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 JBrowse link 5 19,358,734 19,368,431 RGD:6480464
G Cyp7b1 cytochrome P450 family 7 subfamily B member 1 JBrowse link 2 102,701,903 102,871,257 RGD:6480464
G Cyp8b1 cytochrome P450 family 8 subfamily B member 1 JBrowse link 8 130,548,418 130,550,388 RGD:6480464
G Fmr1 fragile X mental retardation 1 JBrowse link X 154,684,924 154,722,369 RGD:6480464
G Fyn FYN proto-oncogene, Src family tyrosine kinase JBrowse link 20 44,436,354 44,630,316 RGD:6480464
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:6480464
G Il2 interleukin 2 JBrowse link 2 123,847,150 123,851,854 RGD:6480464
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:6480464
G Ins2 insulin 2 JBrowse link 1 215,856,967 215,858,034 RGD:6480464
G Map2k1 mitogen activated protein kinase kinase 1 JBrowse link 8 69,134,218 69,722,573 RGD:6480464
G Map2k2 mitogen activated protein kinase kinase 2 JBrowse link 7 11,458,971 11,478,520 RGD:6480464
G Mapk1 mitogen activated protein kinase 1 JBrowse link 11 88,203,863 88,273,301 RGD:6480464
G Mapk3 mitogen activated protein kinase 3 JBrowse link 1 198,192,773 198,198,975 RGD:6480464
G Mgll monoglyceride lipase JBrowse link 4 120,671,436 120,773,458 RGD:6480464
G Pparg peroxisome proliferator-activated receptor gamma JBrowse link 4 147,274,055 147,399,383 RGD:6480464
G Ptgs1 prostaglandin-endoperoxide synthase 1 JBrowse link 3 15,560,685 15,582,339 RGD:6480464
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:6480464
G Rela RELA proto-oncogene, NF-kB subunit JBrowse link 1 220,992,770 221,003,249 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 JBrowse link 10 59,799,123 59,824,208 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19617
    role 19560
      biological role 19553
        biochemical role 19059
          metabolite 19039
            endocannabinoid 53
              2-arachidonoylglycerol 31
Path 2
Term Annotations click to browse term
  CHEBI ontology 19617
    subatomic particle 19613
      composite particle 19613
        hadron 19613
          baryon 19613
            nucleon 19613
              atomic nucleus 19613
                atom 19613
                  main group element atom 19491
                    p-block element atom 19491
                      carbon group element atom 19363
                        carbon atom 19355
                          organic molecular entity 19355
                            organic group 18311
                              organic divalent group 18301
                                organodiyl group 18301
                                  carbonyl group 18186
                                    carbonyl compound 18186
                                      carboxylic acid 17852
                                        monocarboxylic acid 17178
                                          fatty acid 15580
                                            unsaturated fatty acid 887
                                              polyunsaturated fatty acid 644
                                                fatty acid 20:4 308
                                                  icosatetraenoic acid 308
                                                    icosa-5,8,11,14-tetraenoic acid 259
                                                      arachidonic acid 259
                                                        2-arachidonoylglycerol 31
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.