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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:nilotinib
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Accession:CHEBI:52172 term browser browse the term
Definition:A carboxamide that has formula C28H22F3N7O.
Synonyms:exact_synonym: 4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]benzamide
 related_synonym: AMN 107;   AMN107;   Formula=C28H22F3N7O;   InChI=1S/C28H22F3N7O/c1-17-5-6-19(10-25(17)37-27-33-9-7-24(36-27)20-4-3-8-32-14-20)26(39)35-22-11-21(28(29,30)31)12-23(13-22)38-15-18(2)34-16-38/h3-16H,1-2H3,(H,35,39)(H,33,36,37);   InChIKey=HHZIURLSWUIHRB-UHFFFAOYSA-N;   SMILES=Cc1cn(cn1)-c1cc(NC(=O)c2ccc(C)c(Nc3nccc(n3)-c3cccnc3)c2)cc(c1)C(F)(F)F;   nilotinibum
 alt_id: MESH:C498826
 xref: CAS:641571-10-0;   DrugBank:DB04868;   Drug_Central:1932;   KEGG:D08953;   LINCS:LSM-1099
 xref_mesh: MESH:C498826
 xref: Wikipedia:Nilotinib



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nilotinib term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A affects response to substance ISO ABCB1 protein affects the susceptibility to nilotinib CTD PMID:28623111 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcc10 ATP binding cassette subfamily C member 10 multiple interactions ISO nilotinib inhibits the reaction [ABCC10 protein results in decreased abundance of and results in increased secretion of Paclitaxel]; nilotinib inhibits the reaction [ABCC10 protein results in decreased susceptibility to Paclitaxel]; nilotinib inhibits the reaction [ABCC10 protein results in decreased susceptibility to Vincristine] CTD PMID:19841739 NCBI chr 9:14,657,242...14,677,178
Ensembl chr 9:14,657,264...14,677,178
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 affects response to substance ISO ABCG2 protein affects the susceptibility to nilotinib CTD PMID:24954033 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409
JBrowse link
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase multiple interactions
decreases phosphorylation
ISO [nilotinib co-treated with Arsenic Trioxide] results in decreased phosphorylation of ABL1 protein; nilotinib inhibits the reaction [[BCR protein mutant form binds to ABL1 protein mutant form] which results in increased chemical synthesis of Histamine]; nilotinib inhibits the reaction [[BCR protein mutant form binds to ABL1 protein mutant form] which results in increased expression of HDC mRNA]; nilotinib inhibits the reaction [ABL1 protein mutant form results in increased phosphorylation of CRKL protein]; nilotinib inhibits the reaction [ABL1 protein results in increased phosphorylation of ABL1 protein]
nilotinib results in decreased phosphorylation of ABL1 protein; nilotinib results in decreased phosphorylation of ABL1 protein mutant form
CTD PMID:16849647 PMID:19878872 PMID:23883479 NCBI chr 3:14,979,853...15,083,065
Ensembl chr 3:14,979,853...15,083,065
JBrowse link
G Acaca acetyl-CoA carboxylase alpha increases phosphorylation ISO nilotinib results in increased phosphorylation of ACACA protein CTD PMID:23707608 NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457
JBrowse link
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 decreases expression ISO nilotinib results in decreased expression of ALDH1A2 mRNA CTD PMID:31711903 NCBI chr 8:71,877,850...71,957,107
Ensembl chr 8:71,877,850...71,957,107
JBrowse link
G Ap2m1 adaptor related protein complex 2 subunit mu 1 multiple interactions ISO [Arsenic Trioxide co-treated with nilotinib] affects the expression of AP2M1 mRNA CTD PMID:28786057 NCBI chr11:80,355,307...80,364,218
Ensembl chr11:80,328,041...80,364,140
JBrowse link
G Atf6 activating transcription factor 6 multiple interactions
decreases expression
ISO Arsenic Trioxide promotes the reaction [nilotinib results in decreased expression of ATF6 protein] CTD PMID:23883479 NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO
EXP
nilotinib inhibits the reaction [Folic Acid results in increased expression of BAX protein]
nilotinib inhibits the reaction [Cyclosporine results in increased expression of BAX mRNA]; nilotinib inhibits the reaction [Cyclosporine results in increased expression of BAX protein]
CTD PMID:31593741 PMID:33710703 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO nilotinib results in decreased expression of BCL2 protein CTD PMID:26549707 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Bcr BCR activator of RhoGEF and GTPase multiple interactions
decreases phosphorylation
ISO nilotinib inhibits the reaction [[BCR protein mutant form binds to ABL1 protein mutant form] which results in increased chemical synthesis of Histamine]; nilotinib inhibits the reaction [[BCR protein mutant form binds to ABL1 protein mutant form] which results in increased expression of HDC mRNA]
nilotinib results in decreased phosphorylation of BCR protein mutant form
CTD PMID:16849647 PMID:19878872 NCBI chr20:13,471,679...13,596,497
Ensembl chr20:13,471,668...13,597,016
JBrowse link
G C3 complement C3 decreases expression ISO nilotinib results in decreased expression of C3 mRNA CTD PMID:32771489 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429
JBrowse link
G Casp3 caspase 3 increases cleavage
multiple interactions
increases expression
increases activity
ISO
EXP
nilotinib results in increased cleavage of CASP3 protein
nilotinib inhibits the reaction [Cyclosporine results in increased expression of CASP3 mRNA]; nilotinib inhibits the reaction [Cyclosporine results in increased expression of CASP3 protein]
nilotinib results in increased expression of CASP3 protein
nilotinib inhibits the reaction [Folic Acid results in increased expression of CASP3 protein]
benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [nilotinib results in increased cleavage of CASP3 protein]; benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [nilotinib results in increased cleavage of CASP3 protein]
nilotinib results in increased activity of CASP3 protein
CTD PMID:23707608 PMID:23883479 PMID:26549707 PMID:31593741 PMID:32771489 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp7 caspase 7 increases activity
increases cleavage
ISO nilotinib results in increased activity of CASP7 protein
nilotinib results in increased cleavage of CASP7 protein
CTD PMID:23707608 PMID:23883479 NCBI chr 1:255,437,195...255,476,737
Ensembl chr 1:255,437,172...255,476,729
JBrowse link
G Casp9 caspase 9 increases cleavage ISO nilotinib results in increased cleavage of CASP9 protein CTD PMID:26549707 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cltc clathrin heavy chain multiple interactions ISO [Arsenic Trioxide co-treated with nilotinib] affects the expression of CLTC mRNA CTD PMID:28786057 NCBI chr10:71,517,661...71,574,591
Ensembl chr10:71,517,663...71,573,737
JBrowse link
G Crkl CRK like proto-oncogene, adaptor protein decreases phosphorylation
multiple interactions
ISO nilotinib results in decreased phosphorylation of CRKL protein
[nilotinib co-treated with Arsenic Trioxide] results in decreased phosphorylation of CRKL protein; nilotinib inhibits the reaction [ABL1 protein mutant form results in increased phosphorylation of CRKL protein]
CTD PMID:19878872 PMID:23883479 NCBI chr11:83,528,788...83,563,214
Ensembl chr11:83,526,530...83,563,238
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression
multiple interactions
ISO nilotinib results in increased expression of DDIT3 mRNA
Arsenic Trioxide promotes the reaction [nilotinib results in increased expression of DDIT3 mRNA]
CTD PMID:23883479 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Ddr1 discoidin domain receptor tyrosine kinase 1 affects phosphorylation
decreases expression
ISO nilotinib decreased expression of Ddr1 in 3T3 and GD25 cells
nilotinib inhibits collagen mediated DDR1 tyrosine phosphorylation in human cancer cell lines
nilotinib decreases expression of DDR1 mRNA and protein in human pituitary adenoma cells
RGD PMID:28199848 PMID:29438985 PMID:26286316 RGD:151347403, RGD:151347685, RGD:11065574 NCBI chr20:3,042,494...3,064,442
Ensembl chr20:3,044,320...3,064,468
JBrowse link
G Dnm2 dynamin 2 multiple interactions ISO [Arsenic Trioxide co-treated with nilotinib] affects the expression of DNM2 mRNA CTD PMID:28786057 NCBI chr 8:19,978,313...20,060,162
Ensembl chr 8:19,978,400...20,060,157
JBrowse link
G Edem1 ER degradation enhancing alpha-mannosidase like protein 1 increases expression
multiple interactions
ISO nilotinib results in increased expression of EDEM1 mRNA
Arsenic Trioxide promotes the reaction [nilotinib results in increased expression of EDEM1 mRNA]
CTD PMID:23883479 NCBI chr 4:141,797,631...141,829,717
Ensembl chr 4:141,797,701...141,829,717
JBrowse link
G Esr1 estrogen receptor 1 decreases expression ISO nilotinib results in decreased expression of ESR1 protein CTD PMID:32771489 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Eya1 EYA transcriptional coactivator and phosphatase 1 decreases expression ISO nilotinib results in decreased expression of EYA1 mRNA CTD PMID:31711903 NCBI chr 5:4,863,501...5,101,483
Ensembl chr 5:4,955,543...5,101,483
JBrowse link
G Fcer1g Fc epsilon receptor Ig multiple interactions ISO [Arsenic Trioxide co-treated with nilotinib] affects the expression of FCER1G mRNA CTD PMID:28786057 NCBI chr13:83,649,447...83,654,215
Ensembl chr13:83,649,449...83,671,443
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions
ISO nilotinib results in increased expression of FOS mRNA; nilotinib results in increased expression of FOS protein
Arsenic Trioxide promotes the reaction [nilotinib results in increased expression of FOS mRNA]; Arsenic Trioxide promotes the reaction [nilotinib results in increased expression of FOS protein]
CTD PMID:23883479 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Foxc2 forkhead box C2 decreases expression ISO nilotinib results in decreased expression of FOXC2 mRNA CTD PMID:31711903 NCBI chr19:49,186,034...49,188,736
Ensembl chr19:49,185,662...49,188,737
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit multiple interactions
increases expression
ISO Arsenic Trioxide promotes the reaction [nilotinib results in increased expression of GCLM mRNA] CTD PMID:23883479 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
JBrowse link
G Gpt glutamic--pyruvic transaminase increases secretion
multiple interactions
ISO
EXP
nilotinib results in increased secretion of GPT protein
nilotinib inhibits the reaction [Cyclosporine results in increased activity of GPT protein]
CTD PMID:29655783 PMID:33710703 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions EXP nilotinib inhibits the reaction [Cyclosporine results in decreased activity of GSR protein] CTD PMID:33710703 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Hdc histidine decarboxylase decreases expression
multiple interactions
ISO nilotinib results in decreased expression of HDC mRNA
nilotinib inhibits the reaction [[BCR protein mutant form binds to ABL1 protein mutant form] which results in increased expression of HDC mRNA]
CTD PMID:16849647 NCBI chr 3:113,847,256...113,865,334
Ensembl chr 3:113,847,260...113,865,341
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions EXP nilotinib inhibits the reaction [Cyclosporine results in decreased expression of HMOX1 mRNA] CTD PMID:33710703 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hoxb7 homeo box B7 increases expression ISO nilotinib results in increased expression of HOXB7 mRNA CTD PMID:31711903 NCBI chr10:81,252,616...81,256,034
Ensembl chr10:81,252,553...81,256,034
JBrowse link
G Hoxb9 homeo box B9 increases expression ISO nilotinib results in increased expression of HOXB9 mRNA CTD PMID:31711903 NCBI chr10:81,237,312...81,240,818
Ensembl chr10:81,237,312...81,240,818
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression
multiple interactions
ISO nilotinib results in increased expression of HSPA5 mRNA
Arsenic Trioxide promotes the reaction [nilotinib results in increased expression of HSPA5 mRNA]
CTD PMID:23883479 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
JBrowse link
G Il18 interleukin 18 multiple interactions ISO nilotinib inhibits the reaction [Folic Acid results in increased expression of IL18 protein] CTD PMID:31593741 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO
EXP
nilotinib inhibits the reaction [[Galactosamine co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of IL1B protein]; nilotinib inhibits the reaction [Folic Acid results in increased expression of IL1B protein]
nilotinib inhibits the reaction [Cyclosporine results in increased expression of IL1B protein]
CTD PMID:28125915 PMID:31593741 PMID:33710703 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il2 interleukin 2 multiple interactions EXP nilotinib inhibits the reaction [Cyclosporine results in decreased expression of IL2 protein] CTD PMID:33710703 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
JBrowse link
G Il6 interleukin 6 multiple interactions EXP nilotinib inhibits the reaction [Cyclosporine results in increased expression of IL6 protein] CTD PMID:33710703 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
ISO Arsenic Trioxide promotes the reaction [nilotinib results in increased expression of JUN mRNA]; Arsenic Trioxide promotes the reaction [nilotinib results in increased expression of JUN protein]; nilotinib results in increased expression of and results in increased phosphorylation of JUN protein
nilotinib results in increased expression of JUN mRNA; nilotinib results in increased expression of JUN protein
CTD PMID:23883479 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions
ISO nilotinib results in increased expression of JUNB mRNA; nilotinib results in increased expression of JUNB protein
Arsenic Trioxide promotes the reaction [nilotinib results in increased expression of JUNB mRNA]; Arsenic Trioxide promotes the reaction [nilotinib results in increased expression of JUNB protein]
CTD PMID:23883479 NCBI chr19:23,176,265...23,178,049
Ensembl chr19:23,176,294...23,178,035
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO nilotinib results in decreased activity of KCNH2 protein CTD PMID:23707608 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008
JBrowse link
G Meox1 mesenchyme homeobox 1 decreases expression ISO nilotinib results in decreased expression of MEOX1 mRNA CTD PMID:31711903 NCBI chr10:86,818,450...86,837,563
Ensembl chr10:86,818,478...86,837,660
JBrowse link
G Mesp2 mesoderm posterior bHLH transcription factor 2 decreases expression ISO nilotinib results in decreased expression of MESP2 mRNA CTD PMID:31711903 NCBI chr 1:133,756,601...133,759,207
Ensembl chr 1:133,756,601...133,759,198
JBrowse link
G Neurog2 neurogenin 2 increases expression ISO nilotinib results in increased expression of NEUROG2 mRNA CTD PMID:31711903 NCBI chr 2:216,092,641...216,095,276
Ensembl chr 2:216,093,363...216,094,154
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions EXP nilotinib inhibits the reaction [Cyclosporine results in decreased expression of NFE2L2 protein] CTD PMID:33710703 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions EXP nilotinib inhibits the reaction [Cyclosporine results in decreased expression of NFKBIA mRNA] CTD PMID:33710703 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions EXP nilotinib inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of NOS2 mRNA] CTD PMID:21473879 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Olig3 oligodendrocyte transcription factor 3 increases expression ISO nilotinib results in increased expression of OLIG3 mRNA CTD PMID:31711903 NCBI chr 1:14,081,259...14,083,336
Ensembl chr 1:14,081,328...14,082,149
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage
multiple interactions
ISO nilotinib results in increased cleavage of PARP1 protein
benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [nilotinib results in increased cleavage of PARP1 protein]; benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [nilotinib results in increased cleavage of PARP1 protein]
CTD PMID:26549707 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pax3 paired box 3 decreases expression ISO nilotinib results in decreased expression of PAX3 mRNA CTD PMID:31711903 NCBI chr 9:79,567,455...79,664,042
Ensembl chr 9:79,568,634...79,664,042
JBrowse link
G Pax6 paired box 6 increases expression ISO nilotinib results in increased expression of PAX6 mRNA CTD PMID:31711903 NCBI chr 3:92,128,772...92,157,022
Ensembl chr 3:92,135,637...92,157,014
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO nilotinib inhibits the reaction [Folic Acid results in increased expression of RELA protein] CTD PMID:31593741 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Sacs sacsin molecular chaperone increases expression ISO nilotinib results in increased expression of SACS mRNA CTD PMID:29901742 NCBI chr15:35,285,783...35,370,335
Ensembl chr15:35,285,782...35,370,335
JBrowse link
G Sec24b SEC24 homolog B, COPII coat complex component multiple interactions ISO [Arsenic Trioxide co-treated with nilotinib] affects the expression of SEC24B mRNA CTD PMID:28786057 NCBI chr 2:218,562,670...218,632,753
Ensembl chr 2:218,562,676...218,632,699
JBrowse link
G Tcf15 transcription factor 15 decreases expression ISO nilotinib results in decreased expression of TCF15 mRNA CTD PMID:31711903 NCBI chr 3:140,638,984...140,644,766
Ensembl chr 3:140,638,984...140,644,766
JBrowse link
G Tff1 trefoil factor 1 decreases expression ISO nilotinib results in decreased expression of TFF1 mRNA CTD PMID:32771489 NCBI chr20:9,235,736...9,239,597
Ensembl chr20:9,235,736...9,239,597
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP nilotinib inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TGFB1 mRNA] CTD PMID:21473879 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP
ISO
nilotinib inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TNF mRNA]
nilotinib inhibits the reaction [[Galactosamine co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of TNF protein]; nilotinib inhibits the reaction [Folic Acid results in increased expression of TNF protein]
CTD PMID:21473879 PMID:28125915 PMID:31593741 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfsf12 TNF superfamily member 12 multiple interactions ISO nilotinib inhibits the reaction [Folic Acid results in increased expression of TNFSF12 protein] CTD PMID:31593741 NCBI chr10:54,403,870...54,413,213
Ensembl chr10:54,403,870...54,413,213
JBrowse link
G Tp53 tumor protein p53 increases secretion ISO nilotinib results in increased secretion of TP53 protein CTD PMID:29370077 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 decreases activity ISO nilotinib results in decreased activity of UGT1A1 protein CTD PMID:26875642 NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465
JBrowse link
G Uncx UNC homeobox decreases expression ISO nilotinib results in decreased expression of UNCX mRNA CTD PMID:31711903 NCBI chr12:15,092,779...15,097,300
Ensembl chr12:15,092,784...15,097,300
JBrowse link
G Xbp1 X-box binding protein 1 increases expression ISO nilotinib results in increased expression of XBP1 mRNA alternative form CTD PMID:23883479 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693
JBrowse link

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  CHEBI ontology 19659
    role 19634
      biological role 19633
        antimicrobial agent 17784
          antiviral agent 10531
            anticoronaviral agent 9065
              nilotinib 63
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  CHEBI ontology 19659
    subatomic particle 19658
      composite particle 19658
        hadron 19658
          baryon 19658
            nucleon 19658
              atomic nucleus 19700
                atom 19658
                  main group element atom 19607
                    p-block element atom 19607
                      carbon group element atom 19550
                        carbon atom 19547
                          organic molecular entity 19588
                            organic group 18752
                              organic divalent group 18771
                                organodiyl group 18737
                                  carbonyl group 18704
                                    carbonyl compound 18738
                                      carboxylic acid 18409
                                        carboacyl group 17570
                                          univalent carboacyl group 17599
                                            carbamoyl group 17407
                                              carboxamide 17407
                                                secondary carboxamide 581
                                                  nilotinib 63
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