|
G
|
Ache
|
acetylcholinesterase
|
decreases expression multiple interactions
|
EXP
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Fusaric Acid results in decreased expression of ACHE protein Glycyrrhizic Acid inhibits the reaction [Fusaric Acid results in decreased expression of ACHE protein]
|
CTD |
PMID:31150628 |
|
NCBI chr12:25,042,882...25,050,608
Ensembl chr12:25,043,461...25,050,410
|
|
G
|
Akt1
|
AKT serine/threonine kinase 1
|
affects phosphorylation
|
ISO
|
Fusaric Acid affects the phosphorylation of AKT1 protein
|
CTD |
PMID:32156565 |
|
NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610
|
|
G
|
Atg5
|
autophagy related 5
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increases expression
|
ISO
|
Fusaric Acid results in increased expression of ATG5 mRNA
|
CTD |
PMID:30582969 |
|
NCBI chr20:49,380,835...49,471,826
Ensembl chr20:49,380,813...49,471,821
|
|
G
|
Atg7
|
autophagy related 7
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increases expression
|
ISO
|
Fusaric Acid results in increased expression of ATG7 mRNA
|
CTD |
PMID:30582969 |
|
NCBI chr 4:149,390,000...149,597,534
Ensembl chr 4:149,391,390...149,598,319
|
|
G
|
Bdnf
|
brain-derived neurotrophic factor
|
multiple interactions decreases expression
|
EXP
|
Glycyrrhizic Acid inhibits the reaction [Fusaric Acid results in decreased expression of BDNF protein]
|
CTD |
PMID:31150628 |
|
NCBI chr 3:116,619,633...116,670,212
Ensembl chr 3:116,619,633...116,670,657
|
|
G
|
Casp1
|
caspase 1
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decreases expression affects activity
|
ISO
|
Fusaric Acid results in decreased expression of CASP1 mRNA Fusaric Acid affects the activity of CASP1 protein
|
CTD |
PMID:30582969 |
|
NCBI chr 8:10,746,338...10,882,295
Ensembl chr 8:10,746,333...10,882,275
|
|
G
|
Casp3
|
caspase 3
|
multiple interactions decreases expression
|
EXP
|
Glycyrrhizic Acid inhibits the reaction [Fusaric Acid results in decreased expression of CASP3 protein]
|
CTD |
PMID:31150628 |
|
NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
|
|
G
|
Dbh
|
dopamine beta-hydroxylase
|
decreases activity
|
EXP
|
Fusaric Acid results in decreased activity of DBH protein
|
CTD |
PMID:2724147 |
|
NCBI chr 3:30,886,313...30,903,313
Ensembl chr 3:30,886,328...30,903,316
|
|
G
|
Gsk3a
|
glycogen synthase kinase 3 alpha
|
decreases phosphorylation increases phosphorylation
|
ISO
|
Fusaric Acid results in decreased phosphorylation of GSK3A protein Fusaric Acid results in increased phosphorylation of GSK3A protein
|
CTD |
PMID:32156565 |
|
NCBI chr 1:89,943,669...89,953,514
Ensembl chr 1:89,943,669...89,953,593
|
|
G
|
Gsk3b
|
glycogen synthase kinase 3 beta
|
increases phosphorylation
|
ISO
|
Fusaric Acid results in increased phosphorylation of GSK3B protein
|
CTD |
PMID:32156565 |
|
NCBI chr11:76,004,502...76,154,665
Ensembl chr11:76,009,507...76,153,249
|
|
G
|
Hif1a
|
hypoxia inducible factor 1 subunit alpha
|
increases expression multiple interactions affects expression
|
ISO
|
Fusaric Acid results in increased expression of HIF1A mRNA Galactose affects the reaction [Fusaric Acid affects the expression of HIF1A protein]; Glucose affects the reaction [Fusaric Acid affects the expression of HIF1A protein]
|
CTD |
PMID:31654802 |
|
NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:98,359,910...98,405,323
|
|
G
|
Hspd1
|
heat shock protein family D (Hsp60) member 1
|
increases expression
|
ISO
|
Fusaric Acid results in increased expression of HSPD1 protein
|
CTD |
PMID:30582969 |
|
NCBI chr 9:64,073,610...64,084,332
Ensembl chr 9:64,073,611...64,084,037
|
|
G
|
Ikbkb
|
inhibitor of nuclear factor kappa B kinase subunit beta
|
decreases phosphorylation
|
ISO
|
Fusaric Acid results in decreased phosphorylation of IKBKB protein
|
CTD |
PMID:30582969 |
|
NCBI chr16:76,021,968...76,075,717
Ensembl chr16:76,022,008...76,081,911
|
|
G
|
Il1b
|
interleukin 1 beta
|
decreases expression decreases secretion
|
ISO
|
Fusaric Acid results in decreased expression of IL1B mRNA Fusaric Acid results in decreased secretion of IL1B protein
|
CTD |
PMID:30582969 |
|
NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
|
|
G
|
Irak1
|
interleukin-1 receptor-associated kinase 1
|
decreases expression
|
ISO
|
Fusaric Acid results in decreased expression of IRAK1 protein
|
CTD |
PMID:30582969 |
|
NCBI chr X:156,919,927...156,929,825
Ensembl chr X:156,920,081...156,929,825
|
|
G
|
Irak4
|
interleukin-1 receptor-associated kinase 4
|
decreases expression
|
ISO
|
Fusaric Acid results in decreased expression of IRAK4 protein
|
CTD |
PMID:30582969 |
|
NCBI chr 7:127,561,777...127,588,762
Ensembl chr 7:127,561,717...127,597,109
|
|
G
|
Ldha
|
lactate dehydrogenase A
|
multiple interactions increases expression
|
ISO
|
Glucose affects the reaction [Fusaric Acid results in increased expression of LDHA mRNA]
|
CTD |
PMID:31654802 |
|
NCBI chr 1:106,508,092...106,517,512
Ensembl chr 1:106,502,182...106,517,521
|
|
G
|
Mtor
|
mechanistic target of rapamycin kinase
|
affects phosphorylation
|
ISO
|
Fusaric Acid affects the phosphorylation of MTOR protein
|
CTD |
PMID:32156565 |
|
NCBI chr 5:164,167,985...164,277,438
Ensembl chr 5:164,167,928...164,277,435
|
|
G
|
Nfe2l2
|
NFE2 like bZIP transcription factor 2
|
increases phosphorylation
|
ISO
|
Fusaric Acid results in increased phosphorylation of NFE2L2 protein
|
CTD |
PMID:30582969 |
|
NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090
|
|
G
|
Nlrp3
|
NLR family, pyrin domain containing 3
|
decreases expression
|
ISO
|
Fusaric Acid results in decreased expression of NLRP3 mRNA
|
CTD |
PMID:30582969 |
|
NCBI chr10:44,826,299...44,853,373
Ensembl chr10:44,828,014...44,853,394
|
|
G
|
Pdha1
|
pyruvate dehydrogenase E1 subunit alpha 1
|
increases phosphorylation decreases phosphorylation
|
ISO
|
Fusaric Acid results in increased phosphorylation of PDHA1 protein Fusaric Acid results in decreased phosphorylation of PDHA1 protein
|
CTD |
PMID:31654802 PMID:32156565 |
|
NCBI chr X:38,509,158...38,522,986
Ensembl chr X:38,509,084...38,522,536
|
|
G
|
Pdk1
|
pyruvate dehydrogenase kinase 1
|
multiple interactions increases expression affects expression
|
ISO
|
Galactose affects the reaction [Fusaric Acid results in increased expression of PDK1 protein]; Glucose affects the reaction [Fusaric Acid results in increased expression of PDK1 mRNA]; Glucose affects the reaction [Fusaric Acid results in increased expression of PDK1 protein] Fusaric Acid results in increased expression of PDK1 mRNA; Fusaric Acid results in increased expression of PDK1 protein Fusaric Acid affects the expression of PDK1 protein
|
CTD |
PMID:31654802 PMID:32156565 |
|
NCBI chr 3:77,113,464...77,144,145
Ensembl chr 3:77,113,473...77,144,145
|
|
G
|
Pink1
|
PTEN induced kinase 1
|
increases expression
|
ISO
|
Fusaric Acid results in increased expression of PINK1 protein
|
CTD |
PMID:30582969 |
|
NCBI chr 5:155,813,838...155,825,950
Ensembl chr 5:155,813,838...155,825,950
|
|
G
|
Pkm
|
pyruvate kinase M1/2
|
multiple interactions increases expression
|
ISO
|
Galactose affects the reaction [Fusaric Acid results in increased expression of PKM mRNA]; Glucose affects the reaction [Fusaric Acid results in increased expression of PKM mRNA]; Glucose affects the reaction [Fusaric Acid results in increased expression of PKM protein] Fusaric Acid results in increased expression of PKM mRNA; Fusaric Acid results in increased expression of PKM protein
|
CTD |
PMID:31654802 |
|
NCBI chr 8:68,949,731...68,975,394
Ensembl chr 8:68,948,815...68,975,396
|
|
G
|
Rela
|
RELA proto-oncogene, NF-kB subunit
|
increases expression
|
ISO
|
Fusaric Acid results in increased expression of RELA mRNA
|
CTD |
PMID:30582969 |
|
NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817
|
|
G
|
Rps6kb1
|
ribosomal protein S6 kinase B1
|
increases phosphorylation
|
ISO
|
Fusaric Acid results in increased phosphorylation of RPS6KB1 protein
|
CTD |
PMID:32156565 |
|
NCBI chr10:71,817,794...71,865,211
Ensembl chr10:71,815,614...71,865,238
|
|
G
|
Slc2a1
|
solute carrier family 2 member 1
|
affects expression
|
ISO
|
Fusaric Acid affects the expression of SLC2A1 mRNA
|
CTD |
PMID:32156565 |
|
NCBI chr 5:138,002,522...138,030,742
Ensembl chr 5:138,002,522...138,030,742
|
|
G
|
Slc2a4
|
solute carrier family 2 member 4
|
increases expression affects expression
|
ISO
|
Fusaric Acid results in increased expression of SLC2A4 mRNA Fusaric Acid affects the expression of SLC2A4 protein
|
CTD |
PMID:32156565 |
|
NCBI chr10:55,164,721...55,170,289
Ensembl chr10:55,164,721...55,170,270
|
|
G
|
Sod2
|
superoxide dismutase 2
|
increases expression
|
ISO
|
Fusaric Acid results in increased expression of SOD2 mRNA; Fusaric Acid results in increased expression of SOD2 protein
|
CTD |
PMID:30582969 |
|
NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:50,043,325...50,050,168
|
|
G
|
Sqstm1
|
sequestosome 1
|
decreases expression
|
ISO
|
Fusaric Acid results in decreased expression of SQSTM1 protein
|
CTD |
PMID:30582969 |
|
NCBI chr10:35,026,598...35,037,750
Ensembl chr10:35,026,598...35,037,750
|
|
G
|
Tfam
|
transcription factor A, mitochondrial
|
increases expression
|
ISO
|
Fusaric Acid results in increased expression of TFAM protein
|
CTD |
PMID:30582969 |
|
NCBI chr20:17,355,373...17,367,422
Ensembl chr20:17,355,363...17,369,877
|
|
G
|
Tp53
|
tumor protein p53
|
affects phosphorylation
|
ISO
|
Fusaric Acid affects the phosphorylation of TRP53 protein
|
CTD |
PMID:32156565 |
|
NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299
|
|
G
|
Traf6
|
TNF receptor associated factor 6
|
decreases expression
|
ISO
|
Fusaric Acid results in decreased expression of TRAF6 protein
|
CTD |
PMID:30582969 |
|
NCBI chr 3:108,418,537...108,443,330
Ensembl chr 3:108,418,513...108,443,328
|
|
G
|
Ucp2
|
uncoupling protein 2
|
decreases expression
|
ISO
|
Fusaric Acid results in decreased expression of UCP2 protein
|
CTD |
PMID:30582969 |
|
NCBI chr 1:164,251,373...164,257,742
Ensembl chr 1:164,251,373...164,257,743
|
|