CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: coumarin 460
Accession: CHEBI:51938
browse the term
Definition: A 7-aminocoumarin that has formula C14H17NO2.
Synonyms: exact_synonym: 7-(diethylamino)-4-methyl-2H-chromen-2-one
related_synonym: 4-Methyl-7-(diethylamino)coumarin; Coumarin 1; Coumarin 47; Formula=C14H17NO2; InChI=1S/C14H17NO2/c1-4-15(5-2)11-6-7-12-10(3)8-14(16)17-13(12)9-11/h6-9H,4-5H2,1-3H3; InChIKey=AFYCEAFSNDLKSX-UHFFFAOYSA-N; SMILES=CCN(CC)c1ccc2c(C)cc(=O)oc2c1
xref: Beilstein:193303; CAS:91-44-1
xref_mesh: MESH:C002166
G
Akap9
A-kinase anchoring protein 9
increases expression
ISO
4-methyl-7-diethylaminocoumarin results in increased expression of AKAP9 mRNA
CTD
PMID:19502547
NCBI chr 4:30,056,738...30,192,716
Ensembl chr 4:30,056,738...30,192,606
G
Ankrd37
ankyrin repeat domain 37
increases expression
ISO
4-methyl-7-diethylaminocoumarin results in increased expression of ANKRD37 mRNA
CTD
PMID:19502547
NCBI chr16:46,269,025...46,271,971
Ensembl chr16:46,268,443...46,271,963
G
Ar
androgen receptor
multiple interactions affects localization
ISO
4-methyl-7-diethylaminocoumarin binds to and results in increased activity of AR protein 4-methyl-7-diethylaminocoumarin affects the localization of AR protein
CTD
PMID:28478275
NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925
G
Hif1a
hypoxia inducible factor 1 subunit alpha
increases activity
ISO
4-methyl-7-diethylaminocoumarin results in increased activity of HIF1A protein
CTD
PMID:19502547
NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
G
Pfkm
phosphofructokinase, muscle
increases expression
ISO
4-methyl-7-diethylaminocoumarin results in increased expression of PFKM mRNA
CTD
PMID:19502547
NCBI chr 7:129,221,679...129,259,192
Ensembl chr 7:129,221,653...129,259,192
G
Psph
phosphoserine phosphatase
increases expression
ISO
4-methyl-7-diethylaminocoumarin results in increased expression of PSPH mRNA
CTD
PMID:19502547
NCBI chr12:26,882,524...26,905,084
Ensembl chr12:26,883,133...26,905,074
G
Vegfa
vascular endothelial growth factor A
increases expression
ISO
4-methyl-7-diethylaminocoumarin results in increased expression of VEGFA protein
CTD
PMID:19502547
NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
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