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G |
ABCB1 |
ATP binding cassette subfamily B member 1 |
multiple interactions increases secretion increases export |
EXP ISO |
[carvedilol results in decreased activity of ABCB1 protein] which results in increased uptake of fluorexon; [Verapamil results in decreased activity of ABCB1 protein] which results in increased uptake of fluorexon; Beclomethasone inhibits the reaction [ABCB1 protein results in increased export of fluorexon]; Clotrimazole inhibits the reaction [ABCB1 protein results in increased secretion of fluorexon]; Cyclosporine inhibits the reaction [ABCB1 protein results in increased secretion of fluorexon]; desisobutyrylciclesonide inhibits the reaction [ABCB1 protein results in increased export of fluorexon]; Ketoconazole inhibits the reaction [ABCB1 protein results in increased secretion of fluorexon]; Miconazole inhibits the reaction [ABCB1 protein results in increased secretion of fluorexon]; Mometasone Furoate inhibits the reaction [ABCB1 protein results in increased export of fluorexon]; Reserpine inhibits the reaction [ABCB1 protein results in increased secretion of fluorexon]; Troleandomycin inhibits the reaction [ABCB1 protein results in increased secretion of fluorexon]; Verapamil inhibits the reaction [ABCB1 protein results in increased export of fluorexon] Amiodarone inhibits the reaction [ABCB1A protein results in increased secretion of fluorexon]; Clotrimazole inhibits the reaction [ABCB1A protein results in increased secretion of fluorexon]; Cyclosporine inhibits the reaction [ABCB1A protein results in increased secretion of fluorexon]; Ketoconazole inhibits the reaction [ABCB1A protein results in increased secretion of fluorexon]; Miconazole inhibits the reaction [ABCB1A protein results in increased secretion of fluorexon]; Reserpine inhibits the reaction [ABCB1A protein results in increased secretion of fluorexon]; Troleandomycin inhibits the reaction [ABCB1A protein results in increased secretion of fluorexon] |
CTD |
PMID:10571255 PMID:12235267 PMID:16442095 |
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NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323
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G |
ABCC1 |
ATP binding cassette subfamily C member 1 (ABCC1 blood group) |
affects export increases export multiple interactions affects transport increases import |
EXP ISO |
ABCC1 protein affects the export of fluorexon ABCC1 protein results in increased export of fluorexon [Glycyrrhetinic Acid affects the activity of ABCC1 protein] which results in increased abundance of fluorexon; [Indomethacin affects the activity of ABCC1 protein] which results in increased abundance of fluorexon; [matairesinol affects the activity of ABCC1 protein] which results in increased abundance of fluorexon; [verlukast affects the activity of ABCC1 protein] which results in increased abundance of fluorexon; Mefloquine inhibits the reaction [ABCC1 protein affects the export of fluorexon]; nobiletin promotes the reaction [ABCC1 protein results in increased import of fluorexon]; Quercetin inhibits the reaction [ABCC1 protein results in increased export of fluorexon]; robinetin inhibits the reaction [ABCC1 protein affects the export of fluorexon]; Silymarin inhibits the reaction [ABCC1 protein results in increased export of fluorexon]; verlukast inhibits the reaction [ABCC1 protein affects the export of fluorexon]; verlukast inhibits the reaction [ABCC1 protein results in increased export of fluorexon]; Vincristine inhibits the reaction [ABCC1 protein affects the transport of fluorexon] |
CTD |
PMID:10685512 PMID:15670588 PMID:16004972 PMID:16156793 PMID:18204840 PMID:18955043 PMID:26454883 More...
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NCBI chr16:15,949,143...16,143,053
Ensembl chr16:15,949,138...16,143,257
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G |
ABCC2 |
ATP binding cassette subfamily C member 2 |
affects export increases abundance multiple interactions affects transport |
EXP |
ABCC2 protein affects the export of fluorexon ABCC2 protein alternative form results in increased abundance of fluorexon robinetin inhibits the reaction [ABCC2 protein affects the export of fluorexon] ABCC2 protein affects the transport of fluorexon |
CTD |
PMID:15670588 PMID:15848949 PMID:22027652 |
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NCBI chr10:99,782,640...99,852,594
Ensembl chr10:99,782,640...99,852,594
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G |
ABCC6 |
ATP binding cassette subfamily C member 6 |
affects transport |
EXP |
ABCC6 affects the transport of fluorexon |
CTD |
PMID:14667841 |
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NCBI chr16:16,149,565...16,223,494
Ensembl chr16:16,149,565...16,223,522
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G |
ABCB1 |
ATP binding cassette subfamily B member 1 |
multiple interactions increases export increases activity affects export increases secretion increases transport |
EXP ISO |
2-methoxy-N-(3-(4-((3-methyl-4-((6-methyl-3-pyridinyl)oxy)phenyl)amino)-6-quinazolinyl)-2-propenyl)acetamide inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]; [Endosulfan co-treated with Verapamil] inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]; [phosalone co-treated with Verapamil] inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]; [pinostrobin results in decreased activity of ABCB1 protein] which results in decreased export of calcein AM; [tectochrysin results in decreased activity of ABCB1 protein] which results in decreased export of calcein AM; [Verapamil binds to and results in decreased activity of ABCB1 protein] inhibits the reaction [sodium arsenite promotes the reaction [ABCB1 protein results in increased secretion of calcein AM]]; [Verapamil results in decreased activity of ABCB1 protein] which results in decreased export of calcein AM; ABCB1 protein affects the reaction [Mifepristone results in decreased transport of calcein AM]; ABCB1 protein affects the reaction [zosuquidar trihydrochloride results in decreased transport of calcein AM]; Atorvastatin analog inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]; chlorpyrifos-methyl affects the reaction [ABCB1 protein results in increased transport of calcein AM]; Cyclosporine inhibits the reaction [ABCB1 protein affects the export of calcein AM]; deoxynivalenol inhibits the reaction [valspodar inhibits the reaction [ABCB1 protein results in increased export of calcein AM]]; Diazinon inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]; Diazinon promotes the reaction [Endosulfan inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]; Diazinon promotes the reaction [phosalone inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]; Diazinon promotes the reaction [propiconazole inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]; Diazinon promotes the reaction [Verapamil inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]; Endosulfan inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]; Endosulfan inhibits the reaction [phosalone inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]; Endosulfan promotes the reaction [propiconazole inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]; fenoxycarb inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]; fenvalerate inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]; Lovastatin analog inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]; phosalone inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]; phosalone inhibits the reaction [Endosulfan inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]; phosalone inhibits the reaction [propiconazole inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]; propiconazole inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]; propiconazole inhibits the reaction [phosalone inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]; propiconazole promotes the reaction [Endosulfan inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]; propiconazole promotes the reaction [Verapamil inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]; Reserpine inhibits the reaction [ABCB1 protein affects the export of calcein AM]; Simvastatin analog inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]; sodium arsenite promotes the reaction [ABCB1 protein results in increased secretion of calcein AM]; spinosad inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]; valspodar inhibits the reaction [ABCB1 protein results in increased export of calcein AM]; Verapamil inhibits the reaction [ABCB1 protein results in increased export of calcein AM]; Verapamil inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]; Verapamil promotes the reaction [propiconazole inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]] ABCB1A protein promotes the reaction [Emodin results in increased export of calcein AM] calcein AM results in increased activity of ABCB1 protein mutant form |
CTD |
PMID:10617675 PMID:12711602 PMID:15616150 PMID:16121039 PMID:19223659 PMID:19549930 PMID:21321059 PMID:21783720 PMID:29174985 PMID:30217652 PMID:37259354 More...
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NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323
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ABCB11 |
ATP binding cassette subfamily B member 11 |
affects export multiple interactions |
ISO |
ABCB11 protein affects the export of calcein AM ditekiren inhibits the reaction [ABCB11 protein affects the export of calcein AM] |
CTD |
PMID:10617675 |
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NCBI chr 2:168,915,390...169,031,324
Ensembl chr 2:168,915,498...169,031,324
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G |
ABCC1 |
ATP binding cassette subfamily C member 1 (ABCC1 blood group) |
increases transport multiple interactions |
EXP |
ABCC1 protein results in increased transport of calcein AM [ABCC1 protein results in increased susceptibility to Silver Nitrate] which results in decreased export of calcein AM; [ABCC1 protein results in increased susceptibility to Silver] which results in decreased export of calcein AM; [MLN 8237 results in decreased activity of ABCC1 protein] which results in decreased export of calcein AM; [MYC protein results in increased expression of ABCC1 protein] which results in increased export of calcein AM; [verlukast results in decreased activity of ABCC1 protein] which results in decreased export of calcein AM; verlukast inhibits the reaction [ABCC1 protein results in increased transport of calcein AM]; zearalenol metabolite inhibits the reaction [ABCC1 protein results in increased transport of calcein AM]; Zearalenone inhibits the reaction [ABCC1 protein results in increased transport of calcein AM] |
CTD |
PMID:19239227 PMID:19647055 PMID:27376922 PMID:34896433 |
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NCBI chr16:15,949,143...16,143,053
Ensembl chr16:15,949,138...16,143,257
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G |
ABCC2 |
ATP binding cassette subfamily C member 2 |
affects transport multiple interactions increases transport increases export |
EXP ISO |
ABCC2 protein affects the transport of calcein AM Atorvastatin analog inhibits the reaction [ABCC2 protein results in increased transport of calcein AM]; Lovastatin analog inhibits the reaction [ABCC2 protein results in increased transport of calcein AM]; Simvastatin analog inhibits the reaction [ABCC2 protein results in increased transport of calcein AM] [MYC protein results in increased expression of ABCC2 protein] which results in increased export of calcein AM; Atorvastatin analog inhibits the reaction [ABCC2 protein results in increased transport of calcein AM]; Lovastatin analog inhibits the reaction [ABCC2 protein results in increased transport of calcein AM]; montelukast inhibits the reaction [ABCC2 protein results in increased export of calcein AM]; Simvastatin analog inhibits the reaction [ABCC2 protein results in increased transport of calcein AM]; verlukast inhibits the reaction [ABCC2 protein results in increased export of calcein AM]; verlukast inhibits the reaction [ABCC2 protein results in increased transport of calcein AM]; zearalenol inhibits the reaction [ABCC2 protein results in increased transport of calcein AM]; Zearalenone inhibits the reaction [ABCC2 protein results in increased transport of calcein AM] |
CTD |
PMID:15210835 PMID:15616150 PMID:19239227 PMID:19647055 PMID:19952419 |
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NCBI chr10:99,782,640...99,852,594
Ensembl chr10:99,782,640...99,852,594
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ABCC3 |
ATP binding cassette subfamily C member 3 |
affects transport multiple interactions increases transport |
EXP |
ABCC3 protein affects the transport of calcein AM Dexamethasone promotes the reaction [ABCC3 protein affects the transport of calcein AM]; Glutathione promotes the reaction [ABCC3 protein affects the transport of calcein AM]; Hydrocortisone promotes the reaction [ABCC3 protein affects the transport of calcein AM]; Prednisone promotes the reaction [ABCC3 protein affects the transport of calcein AM]; verlukast inhibits the reaction [ABCC3 protein results in increased transport of calcein AM]; zearalenol inhibits the reaction [ABCC3 protein results in increased transport of calcein AM]; Zearalenone inhibits the reaction [ABCC3 protein results in increased transport of calcein AM] |
CTD |
PMID:15210835 PMID:15979871 PMID:19647055 |
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NCBI chr17:50,634,881...50,692,253
Ensembl chr17:50,634,777...50,692,253
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ABCC4 |
ATP binding cassette subfamily C member 4 (PEL blood group) |
multiple interactions |
EXP |
Glutathione promotes the reaction [ABCC4 protein affects the transport of calcein AM] |
CTD |
PMID:15210835 |
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NCBI chr13:95,019,835...95,301,451
Ensembl chr13:95,019,835...95,301,475
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G |
ABCC6 |
ATP binding cassette subfamily C member 6 |
multiple interactions |
EXP |
Glutathione promotes the reaction [ABCC6 protein affects the transport of calcein AM] |
CTD |
PMID:15210835 |
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NCBI chr16:16,149,565...16,223,494
Ensembl chr16:16,149,565...16,223,522
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MYC |
MYC proto-oncogene, bHLH transcription factor |
multiple interactions |
EXP |
[MYC protein results in increased expression of ABCC1 protein] which results in increased export of calcein AM; [MYC protein results in increased expression of ABCC2 protein] which results in increased export of calcein AM |
CTD |
PMID:19239227 |
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NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951
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