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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:methyl ketone
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Accession:CHEBI:51867 term browser browse the term
Definition:A ketone of formula RC(=O)CH3 (R =/= H).
Synonyms:related_synonym: methyl ketones



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(R)-acetoin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1b1 aldo-keto reductase family 1 member B increases reduction
multiple interactions
ISO AKR1B1 protein results in increased reduction of Acetoin
[AKR1B1 protein results in increased reduction of Acetoin] which results in increased chemical synthesis of 2,3-butylene glycol; [AKR1B1 protein results in increased reduction of Diacetyl] which results in increased chemical synthesis of Acetoin
CTD PMID:23295224 NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157
JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 increases reduction
multiple interactions
ISO AKR1B10 protein results in increased reduction of Acetoin
[AKR1B10 protein results in increased reduction of Acetoin] which results in increased chemical synthesis of 2,3-butylene glycol; [AKR1B10 protein results in increased reduction of Diacetyl] which results in increased chemical synthesis of Acetoin
CTD PMID:23295224 NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852
JBrowse link
G Dcxr dicarbonyl and L-xylulose reductase multiple interactions ISO 1,2-naphthoquinone inhibits the reaction [[[DCXR protein co-treated with NAD] results in increased reduction of Diacetyl] which results in increased chemical synthesis of Acetoin]; 1,4-naphthoquinone inhibits the reaction [[[DCXR protein co-treated with NAD] results in increased reduction of Diacetyl] which results in increased chemical synthesis of Acetoin]; 9,10-phenanthrenequinone inhibits the reaction [[[DCXR protein co-treated with NAD] results in increased reduction of Diacetyl] which results in increased chemical synthesis of Acetoin]; [[DCXR protein co-treated with NAD] results in increased reduction of Diacetyl] which results in increased chemical synthesis of Acetoin; [DCXR protein co-treated with NAD] results in increased chemical synthesis of Acetoin; Vitamin K 3 inhibits the reaction [[[DCXR protein co-treated with NAD] results in increased reduction of Diacetyl] which results in increased chemical synthesis of Acetoin] CTD PMID:28595002 NCBI chr10:106,006,404...106,008,294 JBrowse link
2',4',6'-trihydroxyacetophenone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpt glutamic--pyruvic transaminase multiple interactions ISO 2,4,6-trihydroxyacetophenone inhibits the reaction [Acetaminophen results in increased activity of GPT protein] CTD PMID:30287234 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
2,5-hexanedione term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abi2 abl-interactor 2 increases expression EXP 2,5-hexanedione results in increased expression of ABI2 mRNA CTD PMID:22952946 PMID:27466211 NCBI chr 9:61,856,379...61,904,029
Ensembl chr 9:61,827,139...61,905,699
JBrowse link
G Aco2 aconitase 2 increases expression EXP 2,5-hexanedione results in increased expression of ACO2 protein CTD PMID:19033394 NCBI chr 7:113,385,677...113,428,794
Ensembl chr 7:113,385,646...113,428,261
JBrowse link
G Aif1 allograft inflammatory factor 1 increases expression
multiple interactions
EXP 2,5-hexanedione results in increased expression of AIF1 protein
Glyburide inhibits the reaction [2,5-hexanedione results in increased expression of AIF1 protein]
CTD PMID:32522579 PMID:32860822 NCBI chr20:3,646,784...3,652,670
Ensembl chr20:3,646,777...3,652,668
JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases phosphorylation
increases expression
ISO 2,5-hexanedione results in decreased phosphorylation of AKT1 protein
2,5-hexanedione results in increased expression of AKT1 mRNA
CTD PMID:33197454 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Alox15b arachidonate 15-lipoxygenase, type B decreases expression EXP 2,5-hexanedione results in decreased expression of ALOX15B mRNA CTD PMID:22952946 NCBI chr10:53,892,496...53,901,812
Ensembl chr10:53,892,466...53,901,812
JBrowse link
G Angptl4 angiopoietin-like 4 affects expression EXP 2,5-hexanedione affects the expression of ANGPTL4 mRNA CTD PMID:20616210 NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519
JBrowse link
G Arg1 arginase 1 decreases expression
multiple interactions
EXP 2,5-hexanedione results in decreased expression of ARG1 mRNA
Glyburide inhibits the reaction [2,5-hexanedione results in decreased expression of ARG1 mRNA]
CTD PMID:32522579 PMID:32860822 NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO
EXP
2,5-hexanedione results in increased expression of BAX mRNA; 2,5-hexanedione results in increased expression of BAX protein CTD PMID:17492505 PMID:21901545 PMID:22337490 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression
decreases expression
EXP
ISO
2,5-hexanedione results in increased expression of BCL2 protein
2,5-hexanedione results in decreased expression of BCL2 mRNA
2,5-hexanedione results in decreased expression of BCL2 mRNA; 2,5-hexanedione results in decreased expression of BCL2 protein
CTD PMID:17492505 PMID:21901545 PMID:22337490 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bcl2l14 BCL2 like 14 increases expression EXP 2,5-hexanedione results in increased expression of BCL2L14 mRNA CTD PMID:22952946 NCBI chr 4:167,217,561...167,258,723
Ensembl chr 4:167,219,871...167,258,086
JBrowse link
G Bdnf brain-derived neurotrophic factor decreases expression EXP 2,5-hexanedione results in decreased expression of BDNF protein CTD PMID:31760062 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G Bfar bifunctional apoptosis regulator increases expression EXP 2,5-hexanedione results in increased expression of BFAR mRNA CTD PMID:22952946 NCBI chr10:1,552,019...1,585,040
Ensembl chr10:1,552,072...1,585,038
JBrowse link
G Casp1 caspase 1 increases cleavage
increases expression
multiple interactions
EXP 2,5-hexanedione results in increased cleavage of CASP1 protein
2,5-hexanedione results in increased expression of CASP1 mRNA
Glyburide inhibits the reaction [2,5-hexanedione results in increased cleavage of CASP1 protein]
CTD PMID:32522579 PMID:32860822 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
JBrowse link
G Casp3 caspase 3 increases expression ISO
EXP
2,5-hexanedione results in increased expression of CASP3 mRNA; 2,5-hexanedione results in increased expression of CASP3 protein alternative form CTD PMID:17492505 PMID:21901545 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp8 caspase 8 decreases expression ISO 2,5-hexanedione results in decreased expression of CASP8 protein CTD PMID:33197454 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Ccdc171 coiled-coil domain containing 171 increases expression EXP 2,5-hexanedione results in increased expression of CCDC171 mRNA CTD PMID:22952946 NCBI chr 5:97,919,965...98,403,853 JBrowse link
G Ccdc191 coiled-coil domain containing 191 increases expression EXP 2,5-hexanedione results in increased expression of CCDC191 mRNA CTD PMID:22952946 NCBI chr11:56,735,655...56,806,372
Ensembl chr11:56,735,652...56,806,375
JBrowse link
G Cdin1 CDAN1 interacting nuclease 1 increases expression EXP 2,5-hexanedione results in increased expression of CDIN1 mRNA CTD PMID:22952946 NCBI chr 3:102,441,553...102,646,935
Ensembl chr 3:102,441,704...102,646,682
JBrowse link
G Cep112 centrosomal protein 112 increases expression EXP 2,5-hexanedione results in increased expression of CEP112 mRNA CTD PMID:22952946 NCBI chr10:93,366,059...93,833,133
Ensembl chr10:93,366,136...93,833,131
JBrowse link
G Cfap221 cilia and flagella associated protein 221 increases expression EXP 2,5-hexanedione results in increased expression of CFAP221 mRNA CTD PMID:22952946 NCBI chr13:31,046,550...31,118,141
Ensembl chr13:31,046,535...31,116,899
JBrowse link
G Ckmt1 creatine kinase, mitochondrial 1 increases expression EXP 2,5-hexanedione results in increased expression of CKMT1B protein CTD PMID:19033394 NCBI chr 3:108,329,859...108,335,760
Ensembl chr 3:108,330,705...108,335,758
JBrowse link
G Clca2 chloride channel accessory 2 multiple interactions EXP [carbendazim co-treated with 2,5-hexanedione] results in decreased expression of CLCA2 mRNA CTD PMID:22382377 NCBI chr 2:233,993,619...234,022,691
Ensembl chr 2:233,995,078...234,022,199
JBrowse link
G Clu clusterin decreases expression
increases expression
EXP 2,5-hexanedione results in decreased expression of CLU mRNA
2,5-hexanedione results in increased expression of CLU mRNA
CTD PMID:22952946 PMID:27466211 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315
JBrowse link
G Ctxn1 cortexin 1 increases expression EXP 2,5-hexanedione results in increased expression of CTXN1 mRNA CTD PMID:22952946 NCBI chr12:2,610,465...2,612,076 JBrowse link
G Dcn decorin increases expression EXP 2,5-hexanedione results in increased expression of DCN mRNA CTD PMID:22952946 NCBI chr 7:32,281,252...32,321,291
Ensembl chr 7:32,281,252...32,321,270
JBrowse link
G Dennd1a DENN domain containing 1A increases expression EXP 2,5-hexanedione results in increased expression of DENND1A mRNA CTD PMID:22952946 NCBI chr 3:21,564,749...22,052,057
Ensembl chr 3:21,564,749...22,052,062
JBrowse link
G Dicer1 dicer 1 ribonuclease III increases expression ISO 2,5-hexanedione results in increased expression of DICER1 mRNA CTD PMID:33197454 NCBI chr 6:123,627,529...123,692,278
Ensembl chr 6:123,631,250...123,693,965
JBrowse link
G Dnaaf11 dynein axonemal assembly factor 11 increases expression EXP 2,5-hexanedione results in increased expression of DNAAF11 mRNA CTD PMID:22952946 NCBI chr 7:98,141,525...98,245,906
Ensembl chr 7:98,144,763...98,245,837
JBrowse link
G Dnajb4 DnaJ heat shock protein family (Hsp40) member B4 increases expression EXP 2,5-hexanedione results in increased expression of DNAJB4 mRNA CTD PMID:22952946 NCBI chr 2:241,129,346...241,159,272
Ensembl chr 2:241,130,340...241,159,089
JBrowse link
G Dpp7 dipeptidylpeptidase 7 multiple interactions EXP [carbendazim co-treated with 2,5-hexanedione] results in decreased expression of DPP7 mRNA CTD PMID:22382377 NCBI chr 3:8,165,091...8,169,343
Ensembl chr 3:8,165,091...8,169,355
JBrowse link
G Dpysl2 dihydropyrimidinase-like 2 decreases expression EXP 2,5-hexanedione results in decreased expression of DPYSL2 protein CTD PMID:19033394 NCBI chr15:41,005,551...41,111,724
Ensembl chr15:41,005,551...41,111,829
JBrowse link
G Egfr epidermal growth factor receptor increases expression EXP 2,5-hexanedione results in increased expression of EGFR mRNA CTD PMID:16141653 NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Erc1 ELKS/RAB6-interacting/CAST family member 1 increases expression EXP 2,5-hexanedione results in increased expression of ERC1 mRNA CTD PMID:22952946 NCBI chr 4:152,763,664...153,055,706
Ensembl chr 4:152,767,419...153,055,639
JBrowse link
G Faslg Fas ligand increases expression EXP 2,5-hexanedione results in increased expression of FASLG mRNA CTD PMID:22337490 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
JBrowse link
G Fasn fatty acid synthase decreases expression EXP 2,5-hexanedione results in decreased expression of FASN protein CTD PMID:19033394 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
JBrowse link
G Fcer1g Fc fragment of IgE receptor Ig increases expression EXP 2,5-hexanedione results in increased expression of FCER1G mRNA CTD PMID:22952946 NCBI chr13:83,649,447...83,654,215
Ensembl chr13:83,649,449...83,671,443
JBrowse link
G Foxo3 forkhead box O3 increases phosphorylation
decreases expression
ISO 2,5-hexanedione results in increased phosphorylation of FOXO3 protein
2,5-hexanedione results in decreased expression of FOXO3 mRNA
CTD PMID:33197454 NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression EXP 2,5-hexanedione results in increased expression of GADD45 mRNA CTD PMID:16141653 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
JBrowse link
G Gas2 growth arrest-specific 2 increases expression EXP 2,5-hexanedione results in increased expression of GAS2 mRNA CTD PMID:22952946 NCBI chr 1:101,452,361...101,582,619
Ensembl chr 1:101,482,591...101,582,619
JBrowse link
G Gfap glial fibrillary acidic protein decreases expression
increases expression
EXP 2,5-hexanedione results in decreased expression of GFAP protein
2,5-hexanedione results in increased expression of GFAP protein
CTD PMID:19033394 NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589
JBrowse link
G Ghsr growth hormone secretagogue receptor affects expression EXP 2,5-hexanedione affects the expression of GHSR mRNA CTD PMID:20616210 NCBI chr 2:110,268,489...110,271,865
Ensembl chr 2:110,268,489...110,271,865
JBrowse link
G Glud1 glutamate dehydrogenase 1 increases expression EXP 2,5-hexanedione results in increased expression of GLUD1 protein CTD PMID:19033394 NCBI chr16:9,640,312...9,673,961
Ensembl chr16:9,640,312...9,673,957
JBrowse link
G Gsdmd gasdermin D multiple interactions
increases cleavage
EXP Glyburide inhibits the reaction [2,5-hexanedione results in increased cleavage of GSDMD protein] CTD PMID:32522579 PMID:32860822 NCBI chr 7:107,542,242...107,547,052
Ensembl chr 7:107,542,083...107,547,055
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta decreases expression EXP 2,5-hexanedione results in decreased expression of GSK3B protein CTD PMID:31760062 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Gsn gelsolin decreases expression EXP 2,5-hexanedione results in decreased expression of GSN protein CTD PMID:19033394 NCBI chr 3:18,585,166...18,638,404
Ensembl chr 3:18,585,172...18,638,402
JBrowse link
G Gstm3l glutathione S-transferase mu 3-like decreases expression EXP 2,5-hexanedione results in decreased expression of GSTM5 protein CTD PMID:19033394 NCBI chr 2:195,590,450...195,612,578
Ensembl chr 2:195,607,289...195,612,475
JBrowse link
G Gstp1 glutathione S-transferase pi 1 decreases expression EXP 2,5-hexanedione results in decreased expression of GSTP1 mRNA CTD PMID:16141653 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link
G Hdgfl1 HDGF like 1 decreases expression EXP 2,5-hexanedione results in decreased expression of HDGFL1 mRNA CTD PMID:22952946 NCBI chr17:38,207,906...38,209,902 JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B increases expression EXP 2,5-hexanedione results in increased expression of HSPA1B mRNA CTD PMID:16141653 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
JBrowse link
G Ier3 immediate early response 3 affects expression EXP 2,5-hexanedione affects the expression of IER3 mRNA CTD PMID:20616210 NCBI chr20:2,928,378...2,929,582
Ensembl chr20:2,928,378...2,929,583
JBrowse link
G Ift81 intraflagellar transport 81 increases expression EXP 2,5-hexanedione results in increased expression of IFT81 mRNA CTD PMID:22952946 NCBI chr12:33,957,744...34,037,164
Ensembl chr12:33,957,806...34,037,057
JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 decreases expression EXP 2,5-hexanedione results in decreased expression of IGFBP3 mRNA CTD PMID:16141653 NCBI chr14:82,056,347...82,064,083
Ensembl chr14:82,056,347...82,064,083
JBrowse link
G Il1b interleukin 1 beta increases expression
multiple interactions
EXP 2,5-hexanedione results in increased expression of IL1B mRNA; 2,5-hexanedione results in increased expression of IL1B protein
Glyburide inhibits the reaction [2,5-hexanedione results in increased expression of IL1B protein]
CTD PMID:16141653 PMID:32522579 PMID:32860822 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Ina internexin neuronal intermediate filament protein, alpha decreases expression EXP 2,5-hexanedione results in decreased expression of INA protein CTD PMID:19033394 NCBI chr 1:245,896,775...245,908,330
Ensembl chr 1:245,896,775...245,908,330
JBrowse link
G Itgam integrin subunit alpha M increases expression
multiple interactions
ISO
EXP
2,5-hexanedione results in increased expression of ITGAM protein
Glyburide inhibits the reaction [2,5-hexanedione results in increased expression of ITGAM protein]
CTD PMID:19464574 PMID:32522579 PMID:32860822 NCBI chr 1:182,659,047...182,709,495
Ensembl chr 1:182,659,000...182,709,503
JBrowse link
G Itgb1 integrin subunit beta 1 decreases expression EXP 2,5-hexanedione results in decreased expression of ITGB1 mRNA CTD PMID:16141653 NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195
JBrowse link
G Kif6 kinesin family member 6 increases expression EXP 2,5-hexanedione results in increased expression of KIF6 mRNA CTD PMID:22952946 NCBI chr 9:11,076,203...11,373,205
Ensembl chr 9:11,072,824...11,373,006
JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase decreases expression
multiple interactions
EXP 2,5-hexanedione results in decreased expression of KIT protein
resveratrol inhibits the reaction [2,5-hexanedione results in decreased expression of KIT protein]
CTD PMID:17725299 NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652
JBrowse link
G Loxl1 lysyl oxidase-like 1 increases expression
multiple interactions
EXP 2,5-hexanedione results in increased expression of LOXL1 protein
2,5-hexanedione promotes the reaction [carbendazim results in increased expression of LOXL1 protein]; [carbendazim co-treated with 2,5-hexanedione] results in decreased expression of LOXL1 mRNA
CTD PMID:22382377 NCBI chr 8:58,692,592...58,716,356
Ensembl chr 8:58,692,593...58,716,356
JBrowse link
G Lrrc69 leucine rich repeat containing 69 increases expression EXP 2,5-hexanedione results in increased expression of LRRC69 mRNA CTD PMID:22952946 NCBI chr 5:28,023,591...28,181,963
Ensembl chr 5:28,023,593...28,214,384
JBrowse link
G Lyz2 lysozyme 2 decreases expression
increases expression
EXP 2,5-hexanedione results in decreased expression of LYZ2 mRNA
2,5-hexanedione results in increased expression of LYZ2 mRNA
CTD PMID:22952946 NCBI chr 7:52,906,810...52,912,154
Ensembl chr 7:52,906,811...52,912,106
JBrowse link
G Macrod1 mono-ADP ribosylhydrolase 1 increases expression
multiple interactions
EXP 2,5-hexanedione results in increased expression of MACROD1 mRNA
[carbendazim co-treated with 2,5-hexanedione] results in decreased expression of MACROD1 mRNA
CTD PMID:22382377 NCBI chr 1:204,246,238...204,387,027
Ensembl chr 1:204,246,166...204,389,716
JBrowse link
G Map1a microtubule-associated protein 1A decreases expression EXP 2,5-hexanedione results in decreased expression of MAP1A protein CTD PMID:20554699 NCBI chr 3:108,263,217...108,283,936
Ensembl chr 3:108,263,151...108,282,899
JBrowse link
G Map1b microtubule-associated protein 1B decreases expression EXP 2,5-hexanedione results in decreased expression of MAP1B protein; 2,5-hexanedione results in decreased expression of MAP1B protein modified form CTD PMID:20554699 PMID:31760062 NCBI chr 2:30,817,261...30,910,458
Ensembl chr 2:30,817,261...30,910,317
JBrowse link
G Map2 microtubule-associated protein 2 decreases expression EXP 2,5-hexanedione results in decreased expression of MAP2 protein modified form CTD PMID:20554699 NCBI chr 9:67,723,422...67,981,886
Ensembl chr 9:67,723,371...67,979,809
JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 increases expression EXP 2,5-hexanedione results in increased expression of MAP3K1 protein CTD PMID:31760062 NCBI chr 2:43,348,572...43,414,706
Ensembl chr 2:43,350,098...43,414,463
JBrowse link
G Mapt microtubule-associated protein tau decreases expression EXP 2,5-hexanedione results in decreased expression of MAPT protein modified form CTD PMID:20554699 NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129
JBrowse link
G Mbp myelin basic protein multiple interactions
decreases expression
EXP Glyburide inhibits the reaction [2,5-hexanedione results in decreased expression of MBP protein] CTD PMID:32522579 PMID:32860822 NCBI chr18:75,855,878...75,966,404
Ensembl chr18:75,855,878...75,966,404
JBrowse link
G Mdh1 malate dehydrogenase 1 increases expression EXP 2,5-hexanedione results in increased expression of MDH1 protein CTD PMID:19033394 NCBI chr14:95,630,625...95,645,920
Ensembl chr14:95,630,306...95,645,925
JBrowse link
G Mfap3l microfibril associated protein 3 like increases expression EXP 2,5-hexanedione results in increased expression of MFAP3L mRNA CTD PMID:22952946 NCBI chr16:29,411,643...29,454,665
Ensembl chr16:29,415,849...29,430,863
JBrowse link
G Mir10b microRNA 10b increases expression EXP 2,5-hexanedione results in increased expression of MIR10B mRNA CTD PMID:31760062 NCBI chr 3:59,628,438...59,628,546
Ensembl chr 3:59,628,438...59,628,546
JBrowse link
G Mir1224 microRNA 1224 increases expression EXP 2,5-hexanedione results in increased expression of MIR1224 mRNA CTD PMID:31760062 NCBI chr11:80,306,902...80,306,986
Ensembl chr11:80,306,902...80,306,986
JBrowse link
G Mir125a microRNA 125a increases expression
decreases expression
EXP 2,5-hexanedione results in increased expression of MIR125A mRNA
2,5-hexanedione results in decreased expression of MIR125A mRNA
CTD PMID:31760062 NCBI chr 1:58,677,626...58,677,710
Ensembl chr 1:58,677,626...58,677,710
JBrowse link
G Mir130b microRNA 130b decreases expression EXP 2,5-hexanedione results in decreased expression of MIR130B mRNA CTD PMID:31760062 NCBI chr11:83,880,163...83,880,244
Ensembl chr11:83,880,163...83,880,244
JBrowse link
G Mir134 microRNA 134 decreases expression EXP 2,5-hexanedione results in decreased expression of MIR134 mRNA CTD PMID:31760062 NCBI chr 6:128,748,908...128,748,980 JBrowse link
G Mir155 microRNA 155 decreases expression EXP 2,5-hexanedione results in decreased expression of MIR155 mRNA CTD PMID:31760062 NCBI chr11:23,774,654...23,774,718
Ensembl chr11:23,774,654...23,774,718
JBrowse link
G Mir183 microRNA 183 decreases expression EXP 2,5-hexanedione results in decreased expression of MIR183 mRNA CTD PMID:31760062 NCBI chr 4:58,788,614...58,788,723
Ensembl chr 4:58,788,614...58,788,723
JBrowse link
G Mir193 microRNA 193 increases expression EXP 2,5-hexanedione results in increased expression of MIR193 mRNA CTD PMID:31760062 NCBI chr10:64,672,354...64,672,439 JBrowse link
G Mir193a microRNA 193a decreases expression EXP 2,5-hexanedione results in decreased expression of MIR193A mRNA CTD PMID:31760062 NCBI chr10:64,672,343...64,672,454
Ensembl chr10:64,672,343...64,672,454
JBrowse link
G Mir194-2 microRNA 194-2 decreases expression EXP 2,5-hexanedione results in decreased expression of MIR194-2 mRNA CTD PMID:31760062 NCBI chr 1:203,564,761...203,564,845
Ensembl chr 1:203,564,761...203,564,845
JBrowse link
G Mir196a microRNA 196a increases expression EXP 2,5-hexanedione results in increased expression of MIR196A mRNA CTD PMID:31760062 NCBI chr 7:134,110,400...134,110,509
Ensembl chr 7:134,110,400...134,110,509
JBrowse link
G Mir196c microRNA 196c increases expression EXP 2,5-hexanedione results in increased expression of MIR196C mRNA CTD PMID:31760062 NCBI chr10:81,231,006...81,231,085
Ensembl chr10:81,231,006...81,231,085
JBrowse link
G Mir199a2 microRNA 199a-2 decreases expression EXP 2,5-hexanedione results in decreased expression of MIR199A-2 mRNA; 2,5-hexanedione results in decreased expression of MIR199A2 mRNA CTD PMID:31760062 NCBI chr13:74,582,954...74,583,063
Ensembl chr13:74,582,954...74,583,063
JBrowse link
G Mir200c microRNA 200c decreases expression EXP 2,5-hexanedione results in decreased expression of MIR200C mRNA CTD PMID:31760062 NCBI chr 4:157,523,679...157,523,747 JBrowse link
G Mir202 microRNA 202 decreases expression EXP 2,5-hexanedione results in decreased expression of MIR202 mRNA CTD PMID:31760062 NCBI chr 1:194,754,730...194,754,801
Ensembl chr 1:194,754,730...194,754,801
JBrowse link
G Mir206 microRNA 206 decreases expression EXP 2,5-hexanedione results in decreased expression of MIR206 mRNA CTD PMID:31760062 NCBI chr 9:23,094,249...23,094,332
Ensembl chr 9:23,094,249...23,094,332
JBrowse link
G Mir208a microRNA 208a increases expression EXP 2,5-hexanedione results in increased expression of MIR208A mRNA CTD PMID:31760062 NCBI chr15:28,425,570...28,425,652 JBrowse link
G Mir20a microRNA 20a decreases expression EXP 2,5-hexanedione results in decreased expression of MIR20A mRNA CTD PMID:31760062 NCBI chr15:92,181,084...92,181,168
Ensembl chr15:92,181,084...92,181,168
JBrowse link
G Mir21 microRNA 21 increases expression
decreases expression
EXP 2,5-hexanedione results in increased expression of MIR21 mRNA
2,5-hexanedione results in decreased expression of MIR21 mRNA
CTD PMID:31760062 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348
JBrowse link
G Mir212 microRNA 212 increases expression EXP 2,5-hexanedione results in increased expression of MIR212 mRNA CTD PMID:31760062 NCBI chr10:60,023,403...60,023,513
Ensembl chr10:60,023,403...60,023,513
JBrowse link
G Mir22 microRNA 22 increases expression EXP 2,5-hexanedione results in increased expression of MIR22 mRNA CTD PMID:31760062 NCBI chr10:60,307,039...60,307,133
Ensembl chr10:60,307,039...60,307,133
JBrowse link
G Mir223 microRNA 223 increases expression EXP 2,5-hexanedione results in increased expression of MIR223 mRNA CTD PMID:31760062 NCBI chr  X:61,141,887...61,141,996
Ensembl chr  X:61,141,887...61,141,996
JBrowse link
G Mir224 microRNA 224 increases expression EXP 2,5-hexanedione results in increased expression of MIR224 mRNA CTD PMID:31760062 NCBI chr  X:150,065,088...150,065,169
Ensembl chr  X:150,065,088...150,065,169
JBrowse link
G Mir27a microRNA 27a decreases expression EXP 2,5-hexanedione results in decreased expression of MIR27A mRNA CTD PMID:31760062 NCBI chr19:23,954,831...23,954,917
Ensembl chr19:23,954,831...23,954,917
JBrowse link
G Mir27b microRNA 27b increases expression EXP 2,5-hexanedione results in increased expression of MIR27B mRNA CTD PMID:31760062 NCBI chr17:1,813,427...1,813,523
Ensembl chr17:1,813,426...1,813,529
JBrowse link
G Mir300 microRNA 300 increases expression EXP 2,5-hexanedione results in increased expression of MIR300 mRNA CTD PMID:31760062 NCBI chr 6:128,738,513...128,738,591
Ensembl chr 6:128,738,505...128,738,594
JBrowse link
G Mir30a microRNA 30a increases expression EXP 2,5-hexanedione results in increased expression of MIR30A mRNA CTD PMID:31760062 NCBI chr 9:25,737,600...25,737,670
Ensembl chr 9:25,737,600...25,737,670
JBrowse link
G Mir32 microRNA 32 increases expression EXP 2,5-hexanedione results in increased expression of MIR32 mRNA CTD PMID:31760062 NCBI chr 5:71,596,083...71,596,152
Ensembl chr 5:71,596,083...71,596,152
JBrowse link
G Mir320a microRNA 320a increases expression EXP 2,5-hexanedione results in increased expression of MIR320A mRNA CTD PMID:31760062 NCBI chr15:45,516,392...45,516,473
Ensembl chr15:45,516,392...45,516,473
JBrowse link
G Mir323 microRNA 323 decreases expression EXP 2,5-hexanedione results in decreased expression of MIR323 mRNA CTD PMID:31760062 NCBI chr 6:128,725,539...128,725,624
Ensembl chr 6:128,725,539...128,725,624
JBrowse link
G Mir326 microRNA 326 increases expression EXP 2,5-hexanedione results in increased expression of MIR326 mRNA CTD PMID:31760062 NCBI chr 1:153,854,029...153,854,123
Ensembl chr 1:153,854,029...153,854,123
JBrowse link
G Mir33 microRNA 33 increases expression EXP 2,5-hexanedione results in increased expression of MIR33 mRNA CTD PMID:31760062 NCBI chr 7:113,713,855...113,713,923
Ensembl chr 7:113,713,855...113,713,923
JBrowse link
G Mir330 microRNA 330 increases expression EXP 2,5-hexanedione results in increased expression of MIR330 mRNA CTD PMID:31760062 NCBI chr 1:78,833,178...78,833,274
Ensembl chr 1:78,833,178...78,833,274
JBrowse link
G Mir331 microRNA 331 decreases expression EXP 2,5-hexanedione results in decreased expression of MIR331 mRNA CTD PMID:31760062 NCBI chr 7:28,527,390...28,527,485
Ensembl chr 7:28,527,390...28,527,485
JBrowse link
G Mir339 microRNA 339 increases expression EXP 2,5-hexanedione results in increased expression of MIR339 mRNA CTD PMID:31760062 NCBI chr12:15,277,546...15,277,641
Ensembl chr12:15,277,546...15,277,641
JBrowse link
G Mir344-1 microRNA 344-1 decreases expression EXP 2,5-hexanedione results in decreased expression of MIR344-1 mRNA CTD PMID:31760062 NCBI chr 1:115,306,861...115,306,958 JBrowse link
G Mir345 microRNA 345 increases expression EXP 2,5-hexanedione results in increased expression of MIR345 mRNA CTD PMID:31760062 NCBI chr 6:127,754,027...127,754,122
Ensembl chr 6:127,754,027...127,754,122
JBrowse link
G Mir3556a microRNA 3556a decreases expression EXP 2,5-hexanedione results in decreased expression of MIR3556A mRNA CTD PMID:31760062 NCBI chr 4:59,650,596...59,650,713
Ensembl chr 4:59,650,596...59,650,713
JBrowse link
G Mir3558 microRNA 3558 decreases expression EXP 2,5-hexanedione results in decreased expression of MIR3558 mRNA CTD PMID:31760062 NCBI chr 6:7,181,751...7,181,864
Ensembl chr 6:7,181,751...7,181,864
JBrowse link
G Mir3560 microRNA 3560 decreases expression EXP 2,5-hexanedione results in decreased expression of MIR3560 mRNA CTD PMID:31760062 NCBI chr  X:15,255,308...15,255,419
Ensembl chr  X:15,255,308...15,255,419
JBrowse link
G Mir3573 microRNA 3573 increases expression EXP 2,5-hexanedione results in increased expression of MIR3573 mRNA CTD PMID:31760062 NCBI chr  X:64,259,096...64,259,167
Ensembl chr  X:64,259,096...64,259,167
JBrowse link
G Mir3580 microRNA 3580 decreases expression EXP 2,5-hexanedione results in decreased expression of MIR3580 mRNA CTD PMID:31760062 NCBI chr  X:145,445,018...145,445,098
Ensembl chr  X:145,445,018...145,445,098
JBrowse link
G Mir3593 microRNA 3593 decreases expression EXP 2,5-hexanedione results in decreased expression of MIR3593 mRNA CTD PMID:31760062 NCBI chr 6:73,252,647...73,252,737
Ensembl chr 6:73,252,647...73,252,737
JBrowse link
G Mir370 microRNA 370 decreases expression EXP 2,5-hexanedione results in decreased expression of MIR370 mRNA CTD PMID:31760062 NCBI chr 6:128,572,257...128,572,335
Ensembl chr 6:128,572,257...128,572,335
JBrowse link
G Mir375 microRNA 375 decreases expression EXP 2,5-hexanedione results in decreased expression of MIR375 mRNA CTD PMID:31760062 NCBI chr 9:76,457,911...76,457,985
Ensembl chr 9:76,457,911...76,457,985
JBrowse link
G Mir412 microRNA 412 increases expression EXP 2,5-hexanedione results in increased expression of MIR412 mRNA CTD PMID:31760062 NCBI chr 6:128,757,932...128,758,001
Ensembl chr 6:128,757,926...128,758,005
JBrowse link
G Mir423 microRNA 423 increases expression EXP 2,5-hexanedione results in increased expression of MIR423 mRNA CTD PMID:31760062 NCBI chr10:61,914,142...61,914,220
Ensembl chr10:61,914,133...61,914,226
JBrowse link
G Mir433 microRNA 433 decreases expression EXP 2,5-hexanedione results in decreased expression of MIR433 mRNA CTD PMID:31760062 NCBI chr 6:128,545,119...128,545,211
Ensembl chr 6:128,545,112...128,545,217
JBrowse link
G Mir450a1 microRNA 450a-1 decreases expression EXP 2,5-hexanedione results in decreased expression of MIR450A1 mRNA CTD PMID:31760062 NCBI chr  X:132,801,380...132,801,470 JBrowse link
G Mir487b microRNA 487b increases expression EXP 2,5-hexanedione results in increased expression of MIR487B mRNA CTD PMID:31760062 NCBI chr 6:128,741,485...128,741,566
Ensembl chr 6:128,741,485...128,741,566
JBrowse link
G Mir488 microRNA 488 increases expression EXP 2,5-hexanedione results in increased expression of MIR488 mRNA CTD PMID:31760062 NCBI chr13:70,683,064...70,683,142
Ensembl chr13:70,683,064...70,683,142
JBrowse link
G Mir497 microRNA 497 decreases expression EXP 2,5-hexanedione results in decreased expression of MIR497 mRNA CTD PMID:31760062 NCBI chr10:54,951,514...54,951,582
Ensembl chr10:54,951,505...54,951,584
JBrowse link
G Mir503 microRNA 503 decreases expression EXP 2,5-hexanedione results in decreased expression of MIR503 mRNA CTD PMID:31760062 NCBI chr  X:132,806,303...132,806,373 JBrowse link
G Mir541 microRNA 541 decreases expression EXP 2,5-hexanedione results in decreased expression of MIR541 mRNA CTD PMID:31760062 NCBI chr 6:128,757,016...128,757,105
Ensembl chr 6:128,757,016...128,757,105
JBrowse link
G Mir542 microRNA 542 increases expression EXP 2,5-hexanedione results in increased expression of MIR542 mRNA CTD PMID:31760062 NCBI chr  X:132,802,623...132,802,701 JBrowse link
G Mir551b microRNA 551b decreases expression EXP 2,5-hexanedione results in decreased expression of MIR551B mRNA CTD PMID:31760062 NCBI chr 2:113,989,203...113,989,300
Ensembl chr 2:113,989,203...113,989,300
JBrowse link
G Mir582 microRNA 582 increases expression EXP 2,5-hexanedione results in increased expression of MIR582 mRNA CTD PMID:31760062 NCBI chr 2:40,928,571...40,928,651
Ensembl chr 2:40,928,571...40,928,651
JBrowse link
G Mir652 microRNA 652 decreases expression EXP 2,5-hexanedione results in decreased expression of MIR652 mRNA CTD PMID:31760062 NCBI chr  X:106,343,293...106,343,373
Ensembl chr  X:106,343,293...106,343,373
JBrowse link
G Mir653 microRNA 653 decreases expression EXP 2,5-hexanedione results in decreased expression of MIR653 mRNA CTD PMID:31760062 NCBI chr 4:31,692,714...31,692,810
Ensembl chr 4:31,692,714...31,692,810
JBrowse link
G Mir665 microRNA 665 increases expression EXP 2,5-hexanedione results in increased expression of MIR665 mRNA CTD PMID:31760062 NCBI chr 6:128,539,440...128,539,533
Ensembl chr 6:128,539,440...128,539,533
JBrowse link
G Mir675 microRNA 675 increases expression EXP 2,5-hexanedione results in increased expression of MIR675 mRNA CTD PMID:31760062 NCBI chr 1:197,732,275...197,732,358
Ensembl chr 1:197,732,275...197,732,358
JBrowse link
G Mir743a microRNA 743a increases expression EXP 2,5-hexanedione results in increased expression of MIR743A mRNA CTD PMID:31760062 NCBI chr  X:145,402,692...145,402,767
Ensembl chr  X:145,402,692...145,402,767
JBrowse link
G Mir760 microRNA 760 decreases expression EXP 2,5-hexanedione results in decreased expression of MIR760 mRNA CTD PMID:31760062 NCBI chr 2:210,392,616...210,392,695
Ensembl chr 2:210,392,616...210,392,695
JBrowse link
G Mir770 microRNA 770 increases expression EXP 2,5-hexanedione results in increased expression of MIR770 mRNA CTD PMID:31760062 NCBI chr 6:128,515,843...128,515,918
Ensembl chr 6:128,515,835...128,515,928
JBrowse link
G Mir7a2 microRNA 7a-2 increases expression EXP 2,5-hexanedione results in increased expression of MIR7A2 mRNA CTD PMID:31760062 NCBI chr 1:132,806,420...132,806,514
Ensembl chr 1:132,806,420...132,806,514
JBrowse link
G Mir873 microRNA 873 increases expression EXP 2,5-hexanedione results in increased expression of MIR873 mRNA CTD PMID:31760062 NCBI chr 5:51,356,919...51,356,995
Ensembl chr 5:51,356,919...51,356,995
JBrowse link
G Mir877 microRNA 877 increases expression EXP 2,5-hexanedione results in increased expression of MIR877 mRNA CTD PMID:31760062 NCBI chr20:2,811,476...2,811,560
Ensembl chr20:2,811,476...2,811,560
JBrowse link
G Mir883 microRNA 883 decreases expression EXP 2,5-hexanedione results in decreased expression of MIR883 mRNA CTD PMID:31760062 NCBI chr  X:145,410,566...145,410,642
Ensembl chr  X:145,410,566...145,410,642
JBrowse link
G Mirlet7b microRNA let-7b increases expression EXP 2,5-hexanedione results in increased expression of MIRLET7B mRNA CTD PMID:31760062 NCBI chr 7:116,804,186...116,804,270
Ensembl chr 7:116,804,186...116,804,270
JBrowse link
G Mirlet7i microRNA let-7i increases expression EXP 2,5-hexanedione results in increased expression of MIRLET7I mRNA CTD PMID:31760062 NCBI chr 7:58,642,485...58,642,569
Ensembl chr 7:58,642,480...58,642,571
JBrowse link
G Mrc1 mannose receptor, C type 1 decreases expression
multiple interactions
EXP 2,5-hexanedione results in decreased expression of MRC1 mRNA
Glyburide inhibits the reaction [2,5-hexanedione results in decreased expression of MRC1 mRNA]
CTD PMID:32522579 PMID:32860822 NCBI chr17:77,249,187...77,330,857
Ensembl chr17:77,249,187...77,330,857
JBrowse link
G Mtm1 myotubularin 1 increases expression EXP 2,5-hexanedione results in increased expression of MTM1 mRNA CTD PMID:22952946 NCBI chr 6:488,691...506,964
Ensembl chr 6:488,969...506,860
JBrowse link
G Napa NSF attachment protein alpha decreases expression EXP 2,5-hexanedione results in decreased expression of NAPA protein CTD PMID:19033394 NCBI chr 1:76,787,036...76,805,869
Ensembl chr 1:76,786,932...76,805,869
JBrowse link
G Ndufa10 NADH:ubiquinone oxidoreductase subunit A10 increases expression
decreases expression
EXP 2,5-hexanedione results in increased expression of NDUFA10 protein
2,5-hexanedione results in decreased expression of NDUFA10 protein
CTD PMID:19033394 NCBI chr 9:93,007,034...93,041,825
Ensembl chr 9:93,007,042...93,042,560
JBrowse link
G Nefh neurofilament heavy chain decreases expression EXP 2,5-hexanedione results in decreased expression of NEFH protein CTD PMID:19033394 NCBI chr14:79,830,362...79,840,347
Ensembl chr14:79,830,362...79,840,351
JBrowse link
G Nefl neurofilament light chain decreases expression
multiple interactions
EXP 2,5-hexanedione results in decreased expression of NEFL protein
Glyburide inhibits the reaction [2,5-hexanedione results in decreased expression of NEFL protein]
CTD PMID:19033394 PMID:32522579 PMID:32860822 NCBI chr15:42,301,920...42,305,793
Ensembl chr15:42,301,916...42,305,793
JBrowse link
G Nefm neurofilament medium chain decreases expression EXP 2,5-hexanedione results in decreased expression of NEFM protein CTD PMID:19033394 NCBI chr15:42,360,449...42,365,753
Ensembl chr15:42,360,454...42,365,755
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions
increases expression
EXP Glyburide inhibits the reaction [2,5-hexanedione results in increased expression of NLRP3 protein]
2,5-hexanedione results in increased expression of NLRP3 mRNA; 2,5-hexanedione results in increased expression of NLRP3 protein
CTD PMID:32522579 PMID:32860822 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811
JBrowse link
G Nos2 nitric oxide synthase 2 increases expression
multiple interactions
EXP 2,5-hexanedione results in increased expression of NOS2 mRNA
Glyburide inhibits the reaction [2,5-hexanedione results in increased expression of NOS2 mRNA]
CTD PMID:32522579 PMID:32860822 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nsf N-ethylmaleimide sensitive factor, vesicle fusing ATPase decreases expression EXP 2,5-hexanedione results in decreased expression of NSF protein CTD PMID:19033394 NCBI chr10:88,727,912...88,857,375
Ensembl chr10:88,727,912...88,857,386
JBrowse link
G Nupr2 nuclear protein 2, transcriptional regulator increases expression EXP 2,5-hexanedione results in increased expression of NUPR1L mRNA CTD PMID:22952946 NCBI chr12:26,800,123...26,803,228
Ensembl chr12:26,799,800...26,803,304
JBrowse link
G Pdia3 protein disulfide isomerase family A, member 3 decreases expression EXP 2,5-hexanedione results in decreased expression of PDIA3 protein CTD PMID:19033394 NCBI chr 3:108,388,189...108,412,013
Ensembl chr 3:108,388,245...108,413,236
JBrowse link
G Pdlim3 PDZ and LIM domain 3 decreases expression EXP 2,5-hexanedione results in decreased expression of PDLIM3 protein CTD PMID:19033394 NCBI chr16:46,352,460...46,383,680
Ensembl chr16:46,352,467...46,383,657
JBrowse link
G Pgam1 phosphoglycerate mutase 1 increases expression EXP 2,5-hexanedione results in increased expression of PGAM1 protein CTD PMID:19033394 NCBI chr 1:240,723,832...240,731,443
Ensembl chr 1:240,723,920...240,738,452
JBrowse link
G Phospho1 phosphoethanolamine/phosphocholine phosphatase 1 increases expression EXP 2,5-hexanedione results in increased expression of PHOSPHO1 mRNA CTD PMID:22952946 NCBI chr10:80,762,062...80,769,596
Ensembl chr10:80,760,792...80,770,342
JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha decreases expression ISO 2,5-hexanedione results in decreased expression of PIK3CA mRNA CTD PMID:33197454 NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 decreases expression ISO 2,5-hexanedione results in decreased expression of PIK3R1 protein CTD PMID:33197454 NCBI chr 2:32,878,942...32,963,611
Ensembl chr 2:32,882,032...32,963,631
JBrowse link
G Pim1 Pim-1 proto-oncogene, serine/threonine kinase increases expression EXP 2,5-hexanedione results in increased expression of PIM1 mRNA CTD PMID:22952946 NCBI chr20:7,554,921...7,559,174
Ensembl chr20:7,554,921...7,559,174
JBrowse link
G Pkm pyruvate kinase M1/2 increases expression EXP 2,5-hexanedione results in increased expression of PKM protein CTD PMID:19033394 NCBI chr 8:60,057,629...60,079,600
Ensembl chr 8:60,057,402...60,079,599
JBrowse link
G Pou2f1 POU class 2 homeobox 1 increases expression EXP 2,5-hexanedione results in increased expression of POU2F1 mRNA CTD PMID:22952946 NCBI chr13:78,120,617...78,263,306
Ensembl chr13:78,130,685...78,263,363
JBrowse link
G Prkcsh protein kinase C substrate 80K-H decreases expression EXP 2,5-hexanedione results in decreased expression of PRKCSH protein CTD PMID:19033394 NCBI chr 8:20,534,787...20,546,493
Ensembl chr 8:20,534,880...20,546,492
JBrowse link
G Ptgds prostaglandin D2 synthase increases expression EXP 2,5-hexanedione results in increased expression of PTGDS mRNA CTD PMID:22952946 PMID:27466211 NCBI chr 3:8,281,899...8,284,833
Ensembl chr 3:8,281,899...8,284,833
JBrowse link
G Pycard PYD and CARD domain containing increases expression EXP 2,5-hexanedione results in increased expression of PYCARD mRNA; 2,5-hexanedione results in increased expression of PYCARD protein CTD PMID:32860822 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955
JBrowse link
G Pygb glycogen phosphorylase B decreases expression EXP 2,5-hexanedione results in decreased expression of PYGB protein CTD PMID:19033394 NCBI chr 3:139,611,724...139,658,521
Ensembl chr 3:139,611,749...139,663,553
JBrowse link
G Pygm glycogen phosphorylase, muscle associated decreases expression EXP 2,5-hexanedione results in decreased expression of PYGM protein CTD PMID:19033394 NCBI chr 1:203,690,550...203,705,369
Ensembl chr 1:203,690,533...203,705,368
JBrowse link
G Ralgapa2 Ral GTPase activating protein catalytic subunit alpha 2 increases expression EXP 2,5-hexanedione results in increased expression of RALGAPA2 mRNA CTD PMID:22952946 NCBI chr 3:133,661,955...133,938,821
Ensembl chr 3:133,659,761...133,938,916
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions EXP 2,5-hexanedione results in decreased expression of and affects the localization of RELA protein CTD PMID:22337490 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G RGD1304694 similar to CG9646-PA increases expression EXP 2,5-hexanedione results in increased expression of RGD1304694 mRNA CTD PMID:22952946 NCBI chr 7:116,068,047...116,107,713
Ensembl chr 7:116,071,447...116,107,727
JBrowse link
G RGD1562608 similar to KIAA1328 protein increases expression EXP 2,5-hexanedione results in increased expression of RGD1562608 mRNA CTD PMID:22952946 NCBI chr18:16,488,569...16,776,373
Ensembl chr18:16,489,408...16,775,548
JBrowse link
G Rtkn2 rhotekin 2 increases expression EXP 2,5-hexanedione results in increased expression of RTKN2 mRNA CTD PMID:22952946 NCBI chr20:20,525,256...20,609,951
Ensembl chr20:20,525,256...20,609,951
JBrowse link
G S100z S100 calcium binding protein Z increases expression EXP 2,5-hexanedione results in increased expression of S100Z mRNA CTD PMID:22952946 NCBI chr 2:26,738,780...26,753,611
Ensembl chr 2:26,738,776...26,752,390
JBrowse link
G Sclt1 sodium channel and clathrin linker 1 increases expression EXP 2,5-hexanedione results in increased expression of SCLT1 mRNA CTD PMID:22952946 NCBI chr 2:124,605,445...124,763,964
Ensembl chr 2:124,605,658...124,764,065
JBrowse link
G Septin8 septin 8 decreases expression EXP 2,5-hexanedione results in decreased expression of SEPTIN8 protein CTD PMID:19033394 NCBI chr10:37,684,639...37,713,704
Ensembl chr10:37,684,639...37,713,174
JBrowse link
G Sh2d4a SH2 domain containing 4A decreases expression EXP 2,5-hexanedione results in decreased expression of SH2D4A mRNA CTD PMID:22952946 NCBI chr16:21,339,010...21,409,360
Ensembl chr16:21,340,015...21,409,260
JBrowse link
G Shank3 SH3 and multiple ankyrin repeat domains 3 multiple interactions EXP [carbendazim co-treated with 2,5-hexanedione] affects the expression of SHANK3 mRNA CTD PMID:22382377 NCBI chr 7:120,568,707...120,630,796
Ensembl chr 7:120,570,402...120,630,374
JBrowse link
G Sil1 SIL1 nucleotide exchange factor increases expression EXP 2,5-hexanedione results in increased expression of SIL1 mRNA CTD PMID:22952946 NCBI chr18:26,872,423...27,104,365
Ensembl chr18:26,872,429...27,104,332
JBrowse link
G Slc10a7 solute carrier family 10, member 7 increases expression EXP 2,5-hexanedione results in increased expression of SLC10A7 mRNA CTD PMID:22952946 NCBI chr19:29,183,143...29,407,470
Ensembl chr19:29,183,155...29,407,464
JBrowse link
G Sltm SAFB-like, transcription modulator increases expression EXP 2,5-hexanedione results in increased expression of SLTM mRNA CTD PMID:22952946 NCBI chr 8:71,215,995...71,261,821
Ensembl chr 8:71,216,612...71,261,825
JBrowse link
G Sod3 superoxide dismutase 3 increases expression EXP 2,5-hexanedione results in increased expression of SOD3 mRNA CTD PMID:22952946 PMID:27466211 NCBI chr14:58,610,104...58,615,845
Ensembl chr14:58,609,958...58,615,990
JBrowse link
G Sppl3 signal peptide peptidase like 3 increases expression EXP 2,5-hexanedione results in increased expression of SPPL3 mRNA CTD PMID:22952946 NCBI chr12:41,515,635...41,600,079
Ensembl chr12:41,515,640...41,600,126
JBrowse link
G Sptan1 spectrin, alpha, non-erythrocytic 1 decreases expression EXP 2,5-hexanedione results in decreased expression of SPTAN1 protein CTD PMID:19033394 NCBI chr 3:13,241,164...13,306,047
Ensembl chr 3:13,241,217...13,306,046
JBrowse link
G Stmn1 stathmin 1 decreases expression EXP 2,5-hexanedione results in decreased expression of STMN1 mRNA CTD PMID:22952946 NCBI chr 5:146,680,757...146,687,154
Ensembl chr 5:146,681,436...146,687,154
JBrowse link
G Strbp spermatid perinuclear RNA binding protein increases expression EXP 2,5-hexanedione results in increased expression of STRBP mRNA CTD PMID:22952946 NCBI chr 3:21,328,310...21,467,753
Ensembl chr 3:21,337,855...21,414,949
JBrowse link
G Styxl1 serine/threonine/tyrosine interacting-like 1 increases expression EXP 2,5-hexanedione results in increased expression of STYXL1 mRNA CTD PMID:22952946 NCBI chr12:20,907,410...20,940,232
Ensembl chr12:20,907,435...20,939,752
JBrowse link
G Tax1bp1 Tax1 binding protein 1 increases expression EXP 2,5-hexanedione results in increased expression of TAX1BP1 mRNA CTD PMID:22952946 NCBI chr 4:81,821,991...81,877,906
Ensembl chr 4:81,821,989...81,879,100
JBrowse link
G Tbc1d5 TBC1 domain family, member 5 increases expression EXP 2,5-hexanedione results in increased expression of TBC1D5 mRNA CTD PMID:22952946 NCBI chr 9:3,503,328...4,017,131
Ensembl chr 9:3,513,623...4,016,913
JBrowse link
G Tmem192 transmembrane protein 192 increases expression EXP 2,5-hexanedione results in increased expression of TMEM192 mRNA CTD PMID:22952946 NCBI chr16:24,740,166...24,760,994
Ensembl chr16:24,740,124...24,761,021
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
EXP Glyburide inhibits the reaction [2,5-hexanedione results in increased expression of TNF mRNA] CTD PMID:32522579 PMID:32860822 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tpi1 triosephosphate isomerase 1 increases expression EXP 2,5-hexanedione results in increased expression of TPI1 mRNA; 2,5-hexanedione results in increased expression of TPI1 protein CTD PMID:19033394 PMID:22952946 NCBI chr 4:157,615,283...157,618,813
Ensembl chr 4:157,615,386...157,619,541
JBrowse link
G Uba1 ubiquitin-like modifier activating enzyme 1 increases expression EXP 2,5-hexanedione results in increased expression of UBA1 protein CTD PMID:19033394 NCBI chr  X:1,508,700...1,530,677
Ensembl chr  X:1,508,666...1,530,636
JBrowse link
G Ubn2 ubinuclein 2 increases expression EXP 2,5-hexanedione results in increased expression of UBN2 mRNA CTD PMID:22952946 NCBI chr 4:67,165,278...67,251,562
Ensembl chr 4:67,166,346...67,230,491
JBrowse link
G Uqcrc2 ubiquinol cytochrome c reductase core protein 2 decreases expression EXP 2,5-hexanedione results in decreased expression of UQCRC2 mRNA CTD PMID:22952946 NCBI chr 1:175,167,933...175,198,499
Ensembl chr 1:175,167,894...175,199,453
JBrowse link
G Vim vimentin multiple interactions ISO 2,5-hexanedione promotes the reaction [VIM protein binds to VIM protein] CTD PMID:6361548 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
JBrowse link
G Xiap X-linked inhibitor of apoptosis decreases expression EXP 2,5-hexanedione results in decreased expression of XIAP mRNA CTD PMID:22337490 NCBI chr  X:120,890,537...120,938,413
Ensembl chr  X:120,897,907...120,934,700
JBrowse link
G Zfp169 zinc finger protein 169 decreases expression EXP 2,5-hexanedione results in decreased expression of ZFP169 protein CTD PMID:19033394 NCBI chr17:16,139,204...16,167,242
Ensembl chr17:16,139,253...16,169,914
JBrowse link
G Zfp407 zinc finger protein 407 increases expression EXP 2,5-hexanedione results in increased expression of ZFP407 mRNA CTD PMID:22952946 NCBI chr18:77,571,140...77,970,282
Ensembl chr18:77,571,204...77,974,129
JBrowse link
3',4'-dihydroxyacetophenone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Comt catechol-O-methyltransferase increases methylation ISO COMT protein results in increased methylation of 3,4-dihydroxyacetophenone CTD PMID:11160877 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642
JBrowse link
3,4-dihydroxyacetophenone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Comt catechol-O-methyltransferase increases methylation ISO COMT protein results in increased methylation of 3,4-dihydroxyacetophenone CTD PMID:11160877 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642
JBrowse link
4'-hydroxyacetophenone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adh1 alcohol dehydrogenase 1 (class I) affects binding EXP p-hydroxyacetophenone binds to Adh1 protein RGD PMID:16385241 RGD:1642947 NCBI chr 2:226,797,303...226,808,892
Ensembl chr 2:226,797,303...226,808,892
JBrowse link
G Adk adenosine kinase affects binding EXP 4-hydroxyacetophenone binds to ADK protein CTD PMID:15236443 NCBI chr15:2,863,241...3,246,453
Ensembl chr15:2,863,244...3,246,510
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 affects binding EXP 4-hydroxyacetophenone binds to ALDH1A1 protein CTD PMID:15236443 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
JBrowse link
G Gsta2 glutathione S-transferase alpha 2 affects binding EXP 4-hydroxyacetophenone binds to GSTA2 protein CTD PMID:15236443 NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798
JBrowse link
G Pygl glycogen phosphorylase L affects binding EXP 4-hydroxyacetophenone binds to PYGL protein CTD PMID:15236443 NCBI chr 6:88,697,598...88,740,260
Ensembl chr 6:88,697,593...88,740,310
JBrowse link
4-methoxyacetophenone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmox1 heme oxygenase 1 increases expression ISO 4-acetylanisole results in increased expression of HMOX1 mRNA CTD PMID:26244607 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
4-nitroacetophenone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dhrs3 dehydrogenase/reductase 3 increases metabolic processing ISO DHRS3 protein results in increased metabolism of 4-nitroacetophenone CTD PMID:25451588 NCBI chr 5:156,747,939...156,782,420
Ensembl chr 5:156,747,962...156,782,417
JBrowse link
acenocoumarol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A affects response to substance ISO ABCB1 gene polymorphism affects the susceptibility to Acenocoumarol CTD PMID:18021343 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Apoe apolipoprotein E affects response to substance ISO APOE gene polymorphism affects the susceptibility to Acenocoumarol CTD PMID:15861030 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 affects metabolic processing ISO CYP1A1 protein affects the metabolism of Acenocoumarol CTD PMID:11918509 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 affects metabolic processing ISO CYP1A2 protein affects the metabolism of Acenocoumarol CTD PMID:11918509 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp2c24 cytochrome P450, family 2, subfamily c, polypeptide 24 affects response to substance ISO CYP2C18 gene polymorphism affects the susceptibility to Acenocoumarol CTD PMID:19578179 NCBI chr 1:236,873,967...236,936,238
Ensembl chr 1:236,873,967...236,936,238
JBrowse link
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 affects metabolic processing ISO CYP2C19 protein affects the metabolism of Acenocoumarol CTD PMID:11918509 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
JBrowse link
G F10 coagulation factor X decreases activity EXP Acenocoumarol results in decreased activity of F10 protein CTD PMID:3490277 NCBI chr16:76,468,834...76,488,141
Ensembl chr16:76,468,838...76,488,141
JBrowse link
G F2 coagulation factor II decreases activity EXP Acenocoumarol results in decreased activity of F2 protein CTD PMID:3490277 NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486
JBrowse link
G F5 coagulation factor V decreases activity EXP Acenocoumarol results in decreased activity of F5 protein CTD PMID:3490277 NCBI chr13:76,513,463...76,583,106
Ensembl chr13:76,513,255...76,582,317
JBrowse link
G F7 coagulation factor VII decreases activity EXP Acenocoumarol results in decreased activity of F7 protein CTD PMID:3490277 NCBI chr16:76,489,779...76,500,636
Ensembl chr16:76,489,717...76,500,610
JBrowse link
G F9 coagulation factor IX decreases activity EXP Acenocoumarol results in decreased activity of F9 protein CTD PMID:3490277 NCBI chr  X:138,352,334...138,396,835
Ensembl chr  X:138,352,298...138,396,835
JBrowse link
G Ggcx gamma-glutamyl carboxylase increases activity EXP Acenocoumarol results in increased activity of GGCX protein CTD PMID:3490277 NCBI chr 4:104,469,737...104,485,631
Ensembl chr 4:104,469,765...104,487,063
JBrowse link
G Vkorc1 vitamin K epoxide reductase complex, subunit 1 decreases response to substance
decreases activity
multiple interactions
affects response to substance
increases response to substance
ISO VKORC1 promoter polymorphism results in decreased susceptibility to Acenocoumarol; VKORC1 protein polymorphism results in decreased susceptibility to Acenocoumarol
Acenocoumarol results in decreased activity of VKORC1 protein
Acenocoumarol inhibits the reaction [VKORC1 protein results in increased reduction of Vitamin K 1]
VKORC1 gene polymorphism affects the susceptibility to Acenocoumarol; VKORC1 gene SNP affects the susceptibility to Acenocoumarol; VKORC1 intron SNP affects the susceptibility to Acenocoumarol; VKORC1 polymorphism affects the susceptibility to Acenocoumarol; VKORC1 protein polymorphism affects the susceptibility to Acenocoumarol
VKORC1 protein results in increased susceptibility to Acenocoumarol
CTD PMID:16201835 PMID:16611310 PMID:16869821 PMID:17036862 PMID:18698879 More... NCBI chr 1:182,502,491...182,505,012
Ensembl chr 1:182,500,844...182,505,008
JBrowse link
G Vkorc1l1 vitamin K epoxide reductase complex, subunit 1-like 1 multiple interactions
decreases activity
ISO Acenocoumarol inhibits the reaction [VKORC1L1 protein results in increased reduction of Vitamin K 1]
Acenocoumarol results in decreased activity of VKORC1L1 protein
CTD PMID:29581108 NCBI chr12:26,717,959...26,768,193 JBrowse link
acepromazine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase increases activity ISO Acepromazine results in increased activity of ACHE protein CTD PMID:29614332 NCBI chr12:19,407,359...19,413,713
Ensembl chr12:19,407,360...19,413,651
JBrowse link
acetohexamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alb albumin affects binding ISO Acetohexamide binds to ALB protein; Acetohexamide binds to ALB protein modified form CTD PMID:20435530 PMID:20829128 PMID:20956006 PMID:20974553 PMID:21612784 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Dhrs3 dehydrogenase/reductase 3 increases metabolic processing ISO DHRS3 protein results in increased metabolism of Acetohexamide CTD PMID:25451588 NCBI chr 5:156,747,939...156,782,420
Ensembl chr 5:156,747,962...156,782,417
JBrowse link
acetoin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1b1 aldo-keto reductase family 1 member B increases reduction
multiple interactions
ISO AKR1B1 protein results in increased reduction of Acetoin
[AKR1B1 protein results in increased reduction of Acetoin] which results in increased chemical synthesis of 2,3-butylene glycol; [AKR1B1 protein results in increased reduction of Diacetyl] which results in increased chemical synthesis of Acetoin
CTD PMID:23295224 NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157
JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 increases reduction
multiple interactions
ISO AKR1B10 protein results in increased reduction of Acetoin
[AKR1B10 protein results in increased reduction of Acetoin] which results in increased chemical synthesis of 2,3-butylene glycol; [AKR1B10 protein results in increased reduction of Diacetyl] which results in increased chemical synthesis of Acetoin
CTD PMID:23295224 NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852
JBrowse link
G Dcxr dicarbonyl and L-xylulose reductase multiple interactions ISO 1,2-naphthoquinone inhibits the reaction [[[DCXR protein co-treated with NAD] results in increased reduction of Diacetyl] which results in increased chemical synthesis of Acetoin]; 1,4-naphthoquinone inhibits the reaction [[[DCXR protein co-treated with NAD] results in increased reduction of Diacetyl] which results in increased chemical synthesis of Acetoin]; 9,10-phenanthrenequinone inhibits the reaction [[[DCXR protein co-treated with NAD] results in increased reduction of Diacetyl] which results in increased chemical synthesis of Acetoin]; [[DCXR protein co-treated with NAD] results in increased reduction of Diacetyl] which results in increased chemical synthesis of Acetoin; [DCXR protein co-treated with NAD] results in increased chemical synthesis of Acetoin; Vitamin K 3 inhibits the reaction [[[DCXR protein co-treated with NAD] results in increased reduction of Diacetyl] which results in increased chemical synthesis of Acetoin] CTD PMID:28595002 NCBI chr10:106,006,404...106,008,294 JBrowse link
acetone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adh1 alcohol dehydrogenase 1 (class I) multiple interactions ISO [ADH1 protein results in increased oxidation of allyl alcohol] which results in increased abundance of Acetone CTD PMID:11981770 NCBI chr 2:226,797,303...226,808,892
Ensembl chr 2:226,797,303...226,808,892
JBrowse link
G Cat catalase decreases activity ISO
EXP
Acetone results in decreased activity of CAT protein CTD PMID:16169704 PMID:20127315 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ccnd1 cyclin D1 increases expression ISO Acetone results in increased expression of CCND1 mRNA CTD PMID:12720008 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions EXP Acetone promotes the reaction [Toluene results in increased expression of CYP1A1 protein] CTD PMID:8996725 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions EXP Acetone promotes the reaction [Toluene results in increased expression of CYP1A2 protein] CTD PMID:8996725 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 decreases expression EXP Acetone results in decreased expression of CYP2B1 protein CTD PMID:8267643 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions
increases expression
increases activity
increases metabolic processing
ISO
EXP
[Acetone results in increased activity of CYP2E1 protein] which results in increased oxidation of Benzene; [Acetone results in increased expression of CYP2E1 protein] which results in increased susceptibility to allyl cyanide; Acetone results in increased expression of and results in increased activity of CYP2E1 protein
Acetone results in increased expression of CYP2E1 mRNA; Acetone results in increased expression of CYP2E1 protein
1,2-dichloroethylene inhibits the reaction [Acetone results in increased activity of CYP2E1 protein]; [Acetone co-treated with ciprofibrate] results in increased expression of CYP2E1 protein; [Acetone co-treated with Methylcholanthrene] results in decreased expression of CYP2E1 mRNA; [Acetone co-treated with Methylcholanthrene] results in decreased expression of CYP2E1 protein; [Acetone co-treated with Methylcholanthrene] results in increased activity of CYP2E1 protein; [Acetone co-treated with Methylcholanthrene] results in increased expression of CYP2E1 protein; Acetone promotes the reaction [2-xylene results in increased expression of CYP2E1 protein]; Acetone promotes the reaction [CYP2E1 protein results in increased hydroxylation of 4-nitrophenol]; Acetone promotes the reaction [Toluene results in increased expression of CYP2E1 protein]; Trichloroethylene inhibits the reaction [Acetone results in increased activity of CYP2E1 protein]
CYP2E1 protein results in increased metabolism of Acetone
CTD PMID:1968335 PMID:2241968 PMID:3416296 PMID:3782137 PMID:7587954 More... NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 increases expression ISO Acetone results in increased expression of FGFR2 mRNA CTD PMID:12720008 NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626
JBrowse link
G Fn1 fibronectin 1 increases expression ISO Acetone results in increased expression of FN1 mRNA CTD PMID:33064461 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
JBrowse link
G Il13 interleukin 13 multiple interactions ISO [Acetone co-treated with Olive Oil] results in increased expression of IL13 mRNA CTD PMID:21252390 NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737
JBrowse link
G Il4 interleukin 4 multiple interactions ISO [Acetone co-treated with Olive Oil] results in increased expression of IL4 mRNA CTD PMID:21252390 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Il5 interleukin 5 multiple interactions ISO [Acetone co-treated with Olive Oil] results in increased expression of IL5 mRNA CTD PMID:21252390 NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213
JBrowse link
G Itga5 integrin subunit alpha 5 increases expression ISO Acetone results in increased expression of ITGA5 mRNA CTD PMID:12720008 NCBI chr 7:134,478,963...134,502,837
Ensembl chr 7:134,478,968...134,502,837
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO Acetone results in increased expression of NQO1 mRNA CTD PMID:9496914 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO [Acetone co-treated with Olive Oil] results in increased expression of TNF mRNA CTD PMID:21252390 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Trpm8 transient receptor potential cation channel, subfamily M, member 8 increases response to substance ISO TRPM8 protein results in increased susceptibility to Acetone CTD PMID:17481392 NCBI chr 9:88,897,039...88,990,167
Ensembl chr 9:88,903,880...88,988,552
JBrowse link
acetophenone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh2 aldehyde dehydrogenase 2 family member multiple interactions ISO acetophenone inhibits the reaction [4-dimethylaminocinnamaldehyde binds to ALDH2 protein] CTD PMID:10609638 NCBI chr12:34,949,549...34,982,527 JBrowse link
G Alpp alkaline phosphatase, placental increases chemical synthesis ISO ALPP protein results in increased chemical synthesis of acetophenone CTD PMID:1495895 NCBI chr 9:87,765,846...87,768,606
Ensembl chr 9:87,765,860...87,768,606
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions ISO acetophenone binds to and results in decreased activity of ESR2 protein CTD PMID:27633901 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO acetophenone binds to and results in decreased activity of PPARG protein CTD PMID:27633901 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 increases activity ISO acetophenone results in increased activity of TRPA1 protein CTD PMID:27545873 NCBI chr 5:4,379,999...4,433,243
Ensembl chr 5:4,379,999...4,433,570
JBrowse link
acetophenones term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2a1 cytochrome P450, family 2, subfamily a, polypeptide 1 increases metabolic processing
multiple interactions
ISO CYP2A13 protein results in increased metabolism of Acetophenones
CYP2A13 gene polymorphism inhibits the reaction [CYP2A13 protein results in increased metabolism of Acetophenones]
CTD PMID:18669584 NCBI chr 1:82,231,611...82,244,887
Ensembl chr 1:82,231,611...82,244,887
JBrowse link
alpha-ionone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gna15 G protein subunit alpha 15 increases response to substance
multiple interactions
ISO GNA15 protein results in increased susceptibility to alpha-ionone
[GNA15 protein results in increased susceptibility to alpha-ionone] which results in increased activity of OLFR43 protein
CTD PMID:15598656 NCBI chr 7:8,184,632...8,205,508
Ensembl chr 7:8,184,861...8,205,508
JBrowse link
G Olr1513 olfactory receptor 1513 multiple interactions ISO [GNA15 protein results in increased susceptibility to alpha-ionone] which results in increased activity of OLFR43 protein CTD PMID:15598656 NCBI chr10:59,058,941...59,059,879
Ensembl chr10:59,052,828...59,060,676
JBrowse link
G Olr59 olfactory receptor 59 decreases activity ISO alpha-ionone results in decreased activity of OR51E2 protein CTD PMID:27226631 NCBI chr 1:157,193,051...157,227,707
Ensembl chr 1:157,193,080...157,211,179
JBrowse link
aminoacetone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cat catalase multiple interactions EXP CAT protein results in decreased susceptibility to [aminoacetone co-treated with Copper] CTD PMID:18729331 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions EXP [aminoacetone co-treated with Copper] results in increased expression of GSR mRNA CTD PMID:18729331 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions EXP [aminoacetone co-treated with Copper] results in increased expression of SOD1 mRNA CTD PMID:18729331 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions EXP [aminoacetone co-treated with Copper] results in increased expression of SOD2 mRNA CTD PMID:18729331 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
apocynin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions EXP acetovanillone inhibits the reaction [Particulate Matter results in increased expression of and results in increased activity of ABCB1 protein]; acetovanillone inhibits the reaction [Vehicle Emissions results in increased expression of and results in increased activity of ABCB1 protein] CTD PMID:18474546 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions EXP acetovanillone inhibits the reaction [Mitogens results in increased expression of ACTA2 protein] CTD PMID:29760339 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
JBrowse link
G Agt angiotensinogen multiple interactions
decreases activity
ISO
EXP
[acetovanillone co-treated with AGT protein] results in increased expression of and affects the localization of NFE2L2 protein; acetovanillone inhibits the reaction [Glucose promotes the reaction [AGT protein results in increased phosphorylation of JAK2 protein]]
acetovanillone results in decreased activity of AGT protein
acetovanillone inhibits the reaction [AGT protein results in decreased export of Sodium]; acetovanillone inhibits the reaction [AGT protein results in increased abundance of Oxygen]; acetovanillone inhibits the reaction [AGT protein results in increased abundance of Reactive Oxygen Species]; acetovanillone inhibits the reaction [AGT protein results in increased abundance of Superoxides]; acetovanillone inhibits the reaction [AGT protein results in increased expression of COL1A2 mRNA]; acetovanillone inhibits the reaction [AGT protein results in increased expression of COL1A2 protein]; acetovanillone inhibits the reaction [AGT protein results in increased expression of COL3A1 mRNA]; acetovanillone inhibits the reaction [AGT protein results in increased expression of COL3A1 protein]; acetovanillone inhibits the reaction [AGT protein results in increased expression of PTGS2 protein]
acetovanillone inhibits the reaction [AGT protein results in increased abundance of Superoxides]; acetovanillone inhibits the reaction [AGT protein results in increased activity of PARP1 protein]; acetovanillone inhibits the reaction [AGT protein results in increased expression of EDN1 mRNA]
CTD PMID:14597645 PMID:15502880 PMID:15677497 PMID:16531806 PMID:17224469 More... NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
JBrowse link
G Aif1 allograft inflammatory factor 1 multiple interactions ISO acetovanillone inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin results in increased expression of AIF1 protein]; acetovanillone inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of AIF1 protein] CTD PMID:28202386 PMID:30366073 NCBI chr20:3,646,784...3,652,670
Ensembl chr20:3,646,777...3,652,668
JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B multiple interactions ISO acetovanillone inhibits the reaction [Uric Acid results in increased expression of AKR1B3 mRNA] CTD PMID:30651350 NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO acetovanillone inhibits the reaction [Cadmium results in increased phosphorylation of AKT1 protein] CTD PMID:26514923 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Alb albumin multiple interactions EXP acetovanillone inhibits the reaction [Mitogens results in decreased expression of ALB protein] CTD PMID:29760339 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Alpl alkaline phosphatase, biomineralization associated multiple interactions EXP acetovanillone inhibits the reaction [Palmitic Acid results in increased expression of ALPL mRNA] CTD PMID:24080574 NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446
JBrowse link
G Atf2 activating transcription factor 2 multiple interactions ISO acetovanillone inhibits the reaction [2-aminodiphenyl results in increased phosphorylation of ATF2 protein] CTD PMID:22288910 NCBI chr 3:58,718,323...58,795,280
Ensembl chr 3:58,718,332...58,795,236
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions EXP
ISO
acetovanillone analog inhibits the reaction [Chlorpyrifos results in increased expression of BAX protein]; acetovanillone inhibits the reaction [[Desoxycorticosterone co-treated with Sodium Chloride] results in increased expression of BAX protein]
acetovanillone inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin results in increased expression of BAX protein]
CTD PMID:22431579 PMID:29859868 PMID:30366073 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions EXP
ISO
acetovanillone analog inhibits the reaction [Chlorpyrifos results in decreased expression of BCL2 protein]; acetovanillone inhibits the reaction [[Desoxycorticosterone co-treated with Sodium Chloride] results in decreased expression of BCL2 protein]
acetovanillone inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin results in decreased expression of BCL2 protein]
CTD PMID:22431579 PMID:29859868 PMID:30366073 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions ISO acetovanillone inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin results in decreased expression of BCL2L1 protein] CTD PMID:30366073 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Becn1 beclin 1 multiple interactions EXP acetovanillone analog inhibits the reaction [Chlorpyrifos results in increased expression of BECN1 protein] CTD PMID:29859868 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
JBrowse link
G Bglap bone gamma-carboxyglutamate protein multiple interactions EXP acetovanillone inhibits the reaction [Palmitic Acid results in increased expression of BGLAP mRNA] CTD PMID:24080574 NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495
JBrowse link
G Casp1 caspase 1 multiple interactions ISO acetovanillone inhibits the reaction [Ethanol results in increased expression of CASP1 protein modified form]; acetovanillone inhibits the reaction [tetrachlorobenzoquinone results in increased secretion of CASP1 protein modified form] CTD PMID:26079697 PMID:26901245 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
JBrowse link
G Casp3 caspase 3 multiple interactions EXP
ISO
acetovanillone analog inhibits the reaction [Chlorpyrifos results in increased cleavage of CASP3 protein]; acetovanillone inhibits the reaction [Cisplatin results in increased activity of CASP3 protein]; acetovanillone inhibits the reaction [Ethanol results in increased cleavage of and results in increased activity of CASP3 protein]; acetovanillone inhibits the reaction [Ethanol results in increased expression of CASP3 protein]
acetovanillone inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin results in increased cleavage of CASP3 protein]; acetovanillone inhibits the reaction [Cisplatin results in increased activity of CASP3 protein]
[tempol co-treated with UCF 101 co-treated with acetovanillone] inhibits the reaction [S-Nitrosoglutathione results in increased activity of CASP3 protein]
CTD PMID:20153346 PMID:22147442 PMID:22497828 PMID:24291008 PMID:26522475 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Cat catalase multiple interactions EXP [acetovanillone co-treated with CAT protein] inhibits the reaction [Cyclosporine results in increased expression of NOX4 mRNA]; [acetovanillone results in increased susceptibility to Thioctic Acid] inhibits the reaction [Mitogens results in decreased activity of CAT protein]; acetovanillone inhibits the reaction [Cisplatin results in decreased activity of CAT protein]; acetovanillone inhibits the reaction [Formaldehyde results in increased expression of CAT mRNA]; acetovanillone inhibits the reaction [Mitogens results in decreased activity of CAT protein]; Thioctic Acid promotes the reaction [acetovanillone inhibits the reaction [Mitogens results in decreased activity of CAT protein]] CTD PMID:21983654 PMID:24291008 PMID:29760339 PMID:32298299 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ccl11 C-C motif chemokine ligand 11 multiple interactions ISO acetovanillone inhibits the reaction [TNF protein results in increased expression of CCL11 mRNA] CTD PMID:22414048 NCBI chr10:67,028,328...67,032,929
Ensembl chr10:67,028,328...67,032,926
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO acetovanillone inhibits the reaction [Fructose results in increased secretion of CCL2 protein]; acetovanillone inhibits the reaction [Homocysteine results in increased expression of CCL2 mRNA]; acetovanillone inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]; acetovanillone inhibits the reaction [TNF protein results in increased expression of CCL2 protein] CTD PMID:16845898 PMID:19158351 PMID:22414048 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 multiple interactions ISO acetovanillone inhibits the reaction [TNF protein results in increased expression of CCL5 protein]
acetovanillone inhibits the reaction [TNF protein results in increased expression of CCL5 mRNA]
CTD PMID:10495789 PMID:22414048 NCBI chr10:68,322,826...68,327,365
Ensembl chr10:68,322,829...68,327,377
JBrowse link
G Ccl7 C-C motif chemokine ligand 7 multiple interactions ISO acetovanillone inhibits the reaction [TNF protein results in increased expression of CCL7 mRNA] CTD PMID:22414048 NCBI chr10:67,016,446...67,018,296
Ensembl chr10:67,016,446...67,018,303
JBrowse link
G Cd36 CD36 molecule multiple interactions ISO acetovanillone inhibits the reaction [[Oxygen deficiency results in increased abundance of Reactive Oxygen Species] which results in increased expression of CD36 mRNA] CTD PMID:19640849 NCBI chr 4:17,317,343...17,410,084 JBrowse link
G Cdh3 cadherin 3 multiple interactions ISO acetovanillone inhibits the reaction [Homocysteine results in decreased expression of CDH3 protein] CTD PMID:21647593 NCBI chr19:34,393,596...34,444,084
Ensembl chr19:34,393,727...34,444,084
JBrowse link
G Col1a2 collagen type I alpha 2 chain multiple interactions EXP acetovanillone inhibits the reaction [AGT protein results in increased expression of COL1A2 mRNA]; acetovanillone inhibits the reaction [AGT protein results in increased expression of COL1A2 protein] CTD PMID:16531806 NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867
JBrowse link
G Col3a1 collagen type III alpha 1 chain multiple interactions EXP acetovanillone inhibits the reaction [AGT protein results in increased expression of COL3A1 mRNA]; acetovanillone inhibits the reaction [AGT protein results in increased expression of COL3A1 protein] CTD PMID:16531806 NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions ISO acetovanillone inhibits the reaction [Antimycin A results in decreased phosphorylation of CREB1 protein] CTD PMID:21538410 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Csf2 colony stimulating factor 2 multiple interactions ISO acetovanillone inhibits the reaction [TNF protein results in increased expression of CSF2 mRNA] CTD PMID:22414048 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
JBrowse link
G Ctf1 cardiotrophin 1 multiple interactions ISO acetovanillone inhibits the reaction [cobaltous chloride results in increased expression of CTF1 protein]; acetovanillone inhibits the reaction [Vitamin K 3 results in increased expression of CTF1 protein] CTD PMID:16507596 NCBI chr 1:182,328,035...182,336,346
Ensembl chr 1:182,328,090...182,333,335
JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 multiple interactions ISO acetovanillone inhibits the reaction [TNF protein results in increased expression of CXCL1 mRNA]; acetovanillone inhibits the reaction [TNF protein results in increased expression of CXCL1 protein] CTD PMID:22414048 NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 multiple interactions ISO acetovanillone inhibits the reaction [TNF protein results in increased expression of CXCL10 mRNA]; acetovanillone inhibits the reaction [vanadium pentoxide results in increased expression of CXCL10 mRNA] CTD PMID:18322232 PMID:22414048 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 multiple interactions ISO acetovanillone inhibits the reaction [TNF protein results in increased expression of CXCL1 mRNA]; acetovanillone inhibits the reaction [TNF protein results in increased expression of CXCL1 protein] CTD PMID:22414048 NCBI chr14:17,270,146...17,289,458
Ensembl chr14:17,270,146...17,289,511
JBrowse link
G Cyba cytochrome b-245 alpha chain multiple interactions EXP
ISO
acetovanillone inhibits the reaction [Hydrogen Peroxide results in increased expression of CYBA mRNA]; acetovanillone inhibits the reaction [Hydrogen Peroxide results in increased expression of CYBA protein]
acetovanillone inhibits the reaction [GPX1 protein affects the reaction [Phencyclidine results in increased activity of CYBA protein]]
CTD PMID:23270704 PMID:29037473 NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721
JBrowse link
G Cybb cytochrome b-245 beta chain multiple interactions ISO
EXP
acetovanillone inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of NOX2 mRNA]; acetovanillone inhibits the reaction [Glucose results in increased expression of and results in increased activity of CYBB protein]
acetovanillone inhibits the reaction [Hydrogen Peroxide results in increased expression of CYBB mRNA]; acetovanillone inhibits the reaction [Hydrogen Peroxide results in increased expression of CYBB protein]; acetovanillone inhibits the reaction [Palmitic Acid results in increased expression of CYBB mRNA]
CTD PMID:19878672 PMID:23270704 PMID:24080574 PMID:30797899 NCBI chr  X:13,360,583...13,392,517
Ensembl chr  X:13,359,430...13,392,586
JBrowse link
G Des desmin multiple interactions ISO acetovanillone inhibits the reaction [Homocysteine results in increased expression of DES mRNA]; acetovanillone inhibits the reaction [Homocysteine results in increased expression of DES protein] CTD PMID:20036696 NCBI chr 9:76,850,979...76,858,695
Ensembl chr 9:76,850,982...76,858,699
JBrowse link
G Dmd dystrophin multiple interactions ISO acetovanillone inhibits the reaction [DMD gene mutant form results in increased expression of RELA protein modified form]; acetovanillone inhibits the reaction [DMD gene mutant form results in increased expression of SIRT1 mRNA] CTD PMID:26930420 NCBI chr  X:47,272,324...49,504,219
Ensembl chr  X:47,272,331...49,504,207
JBrowse link
G Edn1 endothelin 1 multiple interactions EXP
ISO
[polyethylene glycol-superoxide dismutase co-treated with acetovanillone] inhibits the reaction [EDN1 protein results in increased expression of and results in increased cleavage of PARP1 protein]; acetovanillone inhibits the reaction [EDN1 protein results in decreased susceptibility to Acetylcholine]; acetovanillone inhibits the reaction [EDN1 protein results in increased abundance of Reactive Oxygen Species]
acetovanillone inhibits the reaction [AGT protein results in increased expression of EDN1 mRNA]
CTD PMID:17391658 PMID:20977430 PMID:22431579 PMID:24932781 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Ednra endothelin receptor type A multiple interactions EXP acetovanillone inhibits the reaction [Oxygen deficiency results in increased expression of EDNRA mRNA]; acetovanillone inhibits the reaction [Oxygen deficiency results in increased expression of EDNRA protein] CTD PMID:23270704 NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049
JBrowse link
G Egfr epidermal growth factor receptor multiple interactions ISO acetovanillone inhibits the reaction [Cadmium results in increased phosphorylation of EGFR protein] CTD PMID:26514923 NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 multiple interactions EXP acetovanillone inhibits the reaction [Oxygen deficiency results in increased expression of EIF2AK3 mRNA]; acetovanillone inhibits the reaction [Oxygen deficiency results in increased expression of EIF2AK3 protein] CTD PMID:23270704 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
JBrowse link
G Ep300 E1A binding protein p300 multiple interactions ISO acetovanillone inhibits the reaction [IL1B promotes the reaction [EP300 protein binds to RELA protein]] CTD PMID:19281832 NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
JBrowse link
G Fn1 fibronectin 1 multiple interactions ISO
EXP
acetovanillone inhibits the reaction [Glucose results in increased secretion of FN1 protein]; acetovanillone inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of FN1 protein]; acetovanillone inhibits the reaction [TNF protein results in increased expression of FN1 mRNA]
acetovanillone inhibits the reaction [Glucose results in increased expression of FN1 protein]
CTD PMID:15086456 PMID:16632126 PMID:22245600 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
JBrowse link
G Fshb follicle stimulating hormone subunit beta multiple interactions EXP acetovanillone inhibits the reaction [Oxygen deficiency results in increased expression of FSHB protein] CTD PMID:23270704 NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370
JBrowse link
G Gad1 glutamate decarboxylase 1 multiple interactions ISO acetovanillone inhibits the reaction [Ketamine results in decreased expression of GAD1 protein] CTD PMID:18063801 NCBI chr 3:55,369,704...55,410,335
Ensembl chr 3:55,369,704...55,410,333
JBrowse link
G Gfap glial fibrillary acidic protein multiple interactions ISO acetovanillone inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of GFAP protein] CTD PMID:30797899 NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589
JBrowse link
G Gja1 gap junction protein, alpha 1 multiple interactions EXP acetovanillone inhibits the reaction [Oxygen deficiency results in decreased expression of GJA1 mRNA]; acetovanillone inhibits the reaction [Oxygen deficiency results in decreased expression of GJA1 protein] CTD PMID:23270704 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
JBrowse link
G Glo1 glyoxalase 1 multiple interactions ISO acetovanillone inhibits the reaction [Pyruvaldehyde results in decreased activity of GLO1 protein] CTD PMID:25042521 NCBI chr20:8,663,617...8,681,661
Ensembl chr20:8,662,801...8,681,649
JBrowse link
G Gna11 G protein subunit alpha 11 multiple interactions EXP acetovanillone inhibits the reaction [Glucose results in increased expression of GNA11 protein]; acetovanillone inhibits the reaction [Streptozocin results in increased expression of GNA11 protein] CTD PMID:20691780 NCBI chr 7:8,163,752...8,177,636
Ensembl chr 7:8,162,750...8,179,812
JBrowse link
G Gnaq G protein subunit alpha q multiple interactions EXP acetovanillone inhibits the reaction [Glucose results in increased expression of GNAQ protein]; acetovanillone inhibits the reaction [Streptozocin results in increased expression of GNAQ protein] CTD PMID:20691780 NCBI chr 1:213,425,631...213,671,947
Ensembl chr 1:213,424,465...213,667,672
JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions EXP
ISO
acetovanillone inhibits the reaction [[Desoxycorticosterone co-treated with Sodium Chloride] results in decreased expression of GPX1 protein]
acetovanillone inhibits the reaction [GPX1 protein affects the reaction [Phencyclidine affects the localization of NCF1 protein]]; acetovanillone inhibits the reaction [GPX1 protein affects the reaction [Phencyclidine results in decreased activity of SOD2 protein]]; acetovanillone inhibits the reaction [GPX1 protein affects the reaction [Phencyclidine results in increased activity of CYBA protein]]; acetovanillone inhibits the reaction [GPX1 protein affects the reaction [Phencyclidine results in increased activity of SOD1 protein]]
CTD PMID:22431579 PMID:29037473 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Gpx3 glutathione peroxidase 3 multiple interactions EXP acetovanillone inhibits the reaction [Formaldehyde results in increased expression of GPX3 mRNA] CTD PMID:21983654 NCBI chr10:39,028,624...39,036,695
Ensembl chr10:39,028,570...39,037,035
JBrowse link
G Gpx4 glutathione peroxidase 4 multiple interactions ISO acetovanillone inhibits the reaction [[Paraquat co-treated with Maneb] results in decreased expression of GPX4 protein] CTD PMID:30797899 NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982
JBrowse link
G Gsdmd gasdermin D multiple interactions ISO acetovanillone inhibits the reaction [tetrachlorobenzoquinone results in increased cleavage of GSDMD protein] CTD PMID:30378427 NCBI chr 7:107,542,242...107,547,052
Ensembl chr 7:107,542,083...107,547,055
JBrowse link
G Gucy1a1 guanylate cyclase 1 soluble subunit alpha 1 increases expression EXP acetovanillone results in increased expression of GUCY1A1 protein CTD PMID:25217652 NCBI chr 2:167,418,615...167,482,293
Ensembl chr 2:167,418,640...167,481,671
JBrowse link
G Gucy1b1 guanylate cyclase 1 soluble subunit beta 1 increases expression EXP acetovanillone results in increased expression of GUCY1B1 protein CTD PMID:25217652 NCBI chr 2:167,348,824...167,398,983
Ensembl chr 2:167,348,825...167,398,916
JBrowse link
G Gypa glycophorin A multiple interactions ISO acetovanillone inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of GYPA protein] CTD PMID:20523355 NCBI chr19:27,450,311...27,465,940 JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha increases expression
multiple interactions
EXP
ISO
acetovanillone results in increased expression of HIF1A protein
acetovanillone inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]
CTD PMID:12595275 PMID:23144690 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Hmgb1 high mobility group box 1 multiple interactions ISO acetovanillone inhibits the reaction [Ethanol results in increased secretion of HMGB1 protein] CTD PMID:26079697 NCBI chr12:5,973,062...5,978,565 JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
decreases expression
ISO
EXP
acetovanillone inhibits the reaction [Cadmium Chloride results in increased activity of HMOX1 protein]; acetovanillone inhibits the reaction [Cadmium Chloride results in increased expression of HMOX1 mRNA]; acetovanillone inhibits the reaction [Cadmium Chloride results in increased expression of HMOX1 protein]; acetovanillone inhibits the reaction [phenethyl isothiocyanate results in increased expression of HMOX1 protein]; acetovanillone inhibits the reaction [sodium arsenite results in increased expression of HMOX1 protein]
acetovanillone inhibits the reaction [Cisplatin results in increased expression of HMOX1 mRNA]
acetovanillone results in decreased expression of HMOX1 mRNA
CTD PMID:19414066 PMID:20934533 PMID:21690482 PMID:24291008 PMID:26945724 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A multiple interactions ISO acetovanillone inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin promotes the reaction [NCF1 protein binds to HTR1A protein]]; acetovanillone inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin promotes the reaction [PRKCD protein binds to HTR1A protein]]; acetovanillone inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin results in increased expression of HTR1A mRNA]; acetovanillone inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin results in increased expression of HTR1A protein] CTD PMID:30366073 NCBI chr 2:36,694,174...36,695,442
Ensembl chr 2:36,694,174...36,695,442
JBrowse link
G Htra2 HtrA serine peptidase 2 multiple interactions ISO [tempol co-treated with UCF 101 co-treated with acetovanillone] inhibits the reaction [S-Nitrosoglutathione affects the localization of HTRA2 protein] CTD PMID:20153346 NCBI chr 4:115,556,914...115,560,202
Ensembl chr 4:115,556,916...115,560,095
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions
decreases expression
ISO acetovanillone inhibits the reaction [2,4,5,2',4',5'-hexachlorobiphenyl results in increased expression of ICAM1 protein]; acetovanillone inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 mRNA]; acetovanillone inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 protein]; acetovanillone inhibits the reaction [tetrachlorobenzoquinone results in increased expression of ICAM1 protein]; acetovanillone inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]
acetovanillone inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]
acetovanillone results in decreased expression of ICAM1 protein
CTD PMID:10495789 PMID:19417757 PMID:19632255 PMID:20920494 PMID:22414048 More... NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Ifnb1 interferon beta 1 multiple interactions ISO acetovanillone inhibits the reaction [vanadium pentoxide results in increased expression of IFNB1 mRNA] CTD PMID:18322232 NCBI chr 5:103,020,969...103,021,523
Ensembl chr 5:103,020,969...103,021,523
JBrowse link
G Ifng interferon gamma multiple interactions EXP
ISO
acetovanillone results in decreased susceptibility to [IFNG protein co-treated with Lipopolysaccharides]
acetovanillone inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin results in increased expression of IFNG protein]
CTD PMID:16307444 PMID:30366073 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Il18 interleukin 18 multiple interactions ISO acetovanillone analog inhibits the reaction [manganese chloride results in increased expression of IL18 mRNA] CTD PMID:28539244 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
JBrowse link
G Il1b interleukin 1 beta multiple interactions
decreases response to substance
ISO
EXP
acetovanillone analog inhibits the reaction [manganese chloride results in increased expression of IL1B mRNA]; acetovanillone inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]
acetovanillone inhibits the reaction [Asbestos, Crocidolite results in increased secretion of IL1B protein]; acetovanillone inhibits the reaction [IL1B promotes the reaction [EP300 protein binds to RELA protein]]; acetovanillone inhibits the reaction [IL1B protein affects the localization of NCF1 protein]; acetovanillone inhibits the reaction [IL1B protein results in increased abundance of Reactive Oxygen Species]; acetovanillone inhibits the reaction [IL1B protein results in increased expression of CXCL8 mRNA]; acetovanillone inhibits the reaction [IL1B protein results in increased expression of MMP13 protein]; acetovanillone inhibits the reaction [IL1B protein results in increased expression of RELA protein modified form]; acetovanillone inhibits the reaction [IL1B protein results in increased expression of VCAM1 mRNA]; acetovanillone inhibits the reaction [IL1B protein results in increased expression of VCAM1 protein]; acetovanillone inhibits the reaction [tetrachlorobenzoquinone results in increased expression of IL1B protein]; acetovanillone inhibits the reaction [tetrachlorobenzoquinone results in increased secretion of IL1B protein modified form]
acetovanillone results in decreased susceptibility to IL1B protein
acetovanillone inhibits the reaction [Ethanol results in increased expression of IL1B protein]; acetovanillone inhibits the reaction [Formaldehyde results in increased expression of IL1B protein]
CTD PMID:18403674 PMID:19005069 PMID:19281832 PMID:21211511 PMID:21983654 More... NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 multiple interactions ISO
EXP
acetovanillone inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin results in increased expression of IL6 protein]; acetovanillone inhibits the reaction [cobaltous chloride results in increased expression of IL6 protein]; acetovanillone inhibits the reaction [di-n-butyltin results in increased expression of IL6 mRNA]; acetovanillone inhibits the reaction [di-n-butyltin results in increased expression of IL6 protein]; acetovanillone inhibits the reaction [Pyruvaldehyde results in increased expression of IL6 protein]
acetovanillone inhibits the reaction [TNF protein results in increased expression of IL6 mRNA]; acetovanillone inhibits the reaction [TNF protein results in increased expression of IL6 protein]
acetovanillone inhibits the reaction [Formaldehyde results in increased expression of IL6 protein]; acetovanillone inhibits the reaction [Mitogens results in increased expression of IL6 protein]; acetovanillone promotes the reaction [Thioctic Acid inhibits the reaction [Mitogens results in increased expression of IL6 protein]]; Thioctic Acid promotes the reaction [acetovanillone inhibits the reaction [Mitogens results in increased expression of IL6 protein]]
CTD PMID:21983654 PMID:22414048 PMID:22472292 PMID:24631921 PMID:25042521 More... NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Itga2b integrin subunit alpha 2b multiple interactions ISO acetovanillone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGA2B protein] CTD PMID:20523355 NCBI chr10:87,408,532...87,426,055
Ensembl chr10:87,408,536...87,426,168
JBrowse link
G Itgam integrin subunit alpha M multiple interactions ISO acetovanillone inhibits the reaction [Fatty Acids, Nonesterified results in increased expression of ITGAM mRNA]
acetovanillone inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of ITGAM protein]; acetovanillone inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of ITGAM protein]
CTD PMID:16357311 PMID:28202386 PMID:30797899 NCBI chr 1:182,659,047...182,709,495
Ensembl chr 1:182,659,000...182,709,503
JBrowse link
G Itgb3 integrin subunit beta 3 multiple interactions ISO acetovanillone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGB3 protein] CTD PMID:20523355 NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679
JBrowse link
G Jak2 Janus kinase 2 multiple interactions ISO acetovanillone inhibits the reaction [Glucose promotes the reaction [AGT protein results in increased phosphorylation of JAK2 protein]] CTD PMID:15677497 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO acetovanillone inhibits the reaction [2-aminodiphenyl results in increased phosphorylation of and results in increased expression of JUN protein] CTD PMID:22288910 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Lep leptin multiple interactions ISO acetovanillone inhibits the reaction [LEP protein affects the abundance of Calcium]; acetovanillone inhibits the reaction [LEP protein results in increased abundance of Superoxides]; acetovanillone inhibits the reaction [LEP protein results in increased expression of NCF1 protein]; acetovanillone inhibits the reaction [LEP protein results in increased expression of NCF2 protein] CTD PMID:16380530 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link
G Lepr leptin receptor multiple interactions ISO acetovanillone inhibits the reaction [LEPR gene mutant form results in decreased susceptibility to Acetylcholine]; acetovanillone inhibits the reaction [LEPR gene mutant form results in increased abundance of Superoxides] CTD PMID:19478208 NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908
JBrowse link
G Lhb luteinizing hormone subunit beta multiple interactions EXP acetovanillone inhibits the reaction [Oxygen deficiency results in increased expression of LHB protein] CTD PMID:23270704 NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972
Ensembl chr 1:95,900,984...95,901,972
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta multiple interactions EXP acetovanillone analog inhibits the reaction [Chlorpyrifos results in increased lipidation of MAP1LC3B protein] CTD PMID:29859868 NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO
EXP
acetovanillone inhibits the reaction [[Paraquat co-treated with Maneb] results in increased phosphorylation of MAPK1 protein]; acetovanillone inhibits the reaction [Cocaine results in increased phosphorylation of and results in increased activity of MAPK1 protein]
acetovanillone inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK1 protein]; acetovanillone inhibits the reaction [TNF protein results in increased phosphorylation of MAPK1 protein]
acetovanillone inhibits the reaction [2-aminodiphenyl results in increased phosphorylation of MAPK1 protein]; acetovanillone inhibits the reaction [[Lipopolysaccharides results in increased abundance of Reactive Oxygen Species] which results in increased phosphorylation of MAPK1 protein]; acetovanillone inhibits the reaction [Cadmium results in increased phosphorylation of MAPK1 protein]; acetovanillone inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; acetovanillone inhibits the reaction [TNF protein results in increased phosphorylation of MAPK1 protein]
CTD PMID:16632126 PMID:20354174 PMID:21391979 PMID:22288910 PMID:23774252 More... NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO
EXP
acetovanillone inhibits the reaction [[Paraquat co-treated with Maneb] results in increased phosphorylation of MAPK3 protein]; acetovanillone inhibits the reaction [Cocaine results in increased phosphorylation of and results in increased activity of MAPK3 protein]
acetovanillone inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK3 protein]; acetovanillone inhibits the reaction [TNF protein results in increased phosphorylation of MAPK3 protein]
acetovanillone inhibits the reaction [2-aminodiphenyl results in increased phosphorylation of MAPK3 protein]; acetovanillone inhibits the reaction [[Lipopolysaccharides results in increased abundance of Reactive Oxygen Species] which results in increased phosphorylation of MAPK3 protein]; acetovanillone inhibits the reaction [Cadmium results in increased phosphorylation of MAPK3 protein]; acetovanillone inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein]; acetovanillone inhibits the reaction [TNF protein results in increased phosphorylation of MAPK3 protein]
CTD PMID:16632126 PMID:20354174 PMID:21391979 PMID:22288910 PMID:23774252 More... NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO acetovanillone inhibits the reaction [Cocaine results in increased phosphorylation of and results in increased activity of MAPK8 protein]
acetovanillone inhibits the reaction [[Lipopolysaccharides results in increased abundance of Reactive Oxygen Species] which results in increased phosphorylation of MAPK8 protein]; acetovanillone inhibits the reaction [Cadmium results in increased phosphorylation of MAPK8 protein]; acetovanillone inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]
CTD PMID:20354174 PMID:21391979 PMID:24967690 PMID:26514923 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions ISO acetovanillone inhibits the reaction [[Lipopolysaccharides results in increased abundance of Reactive Oxygen Species] which results in increased phosphorylation of MAPK9 protein]; acetovanillone inhibits the reaction [Cadmium results in increased phosphorylation of MAPK9 protein]; acetovanillone inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK9 protein] CTD PMID:21391979 PMID:24967690 PMID:26514923 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178
JBrowse link
G Mif macrophage migration inhibitory factor multiple interactions ISO acetovanillone inhibits the reaction [TNF protein results in increased expression of MIF mRNA] CTD PMID:22414048 NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504
JBrowse link
G Mlkl mixed lineage kinase domain like pseudokinase multiple interactions ISO acetovanillone inhibits the reaction [tetrachlorobenzoquinone results in increased expression of MLKL protein] CTD PMID:30378427 NCBI chr19:39,278,123...39,304,555
Ensembl chr19:39,276,785...39,304,502
JBrowse link
G Mmp13 matrix metallopeptidase 13 multiple interactions ISO acetovanillone inhibits the reaction [IL1B protein results in increased expression of MMP13 protein]; acetovanillone inhibits the reaction [TNF protein results in increased expression of MMP13 protein] CTD PMID:21211511 NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions EXP
ISO
acetovanillone inhibits the reaction [Oxygen deficiency results in increased expression of MMP9 mRNA]; acetovanillone inhibits the reaction [Oxygen deficiency results in increased expression of MMP9 protein]; acetovanillone inhibits the reaction [RELA protein binds to MMP9 promoter]; acetovanillone inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of MMP9 protein]; acetovanillone inhibits the reaction [TNF protein results in increased expression of MMP9 mRNA]
acetovanillone inhibits the reaction [Hydrogen Peroxide results in increased expression of MMP9 mRNA]
CTD PMID:23270704 PMID:23774252 PMID:26514923 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Mpo myeloperoxidase decreases expression
multiple interactions
ISO
EXP
acetovanillone results in decreased expression of MPO protein
acetovanillone inhibits the reaction [Cisplatin results in increased activity of MPO protein]
CTD PMID:19417757 PMID:24291008 NCBI chr10:72,594,458...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Msr1 macrophage scavenger receptor 1 multiple interactions ISO acetovanillone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA] CTD PMID:9614211 NCBI chr16:52,717,775...52,802,890
Ensembl chr16:52,717,732...52,799,676
JBrowse link
G Ncf1 neutrophil cytosolic factor 1 multiple interactions ISO
EXP
acetovanillone inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin promotes the reaction [NCF1 protein binds to HTR1A protein]]; acetovanillone inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin promotes the reaction [NCF1 protein binds to PRKCD protein]]; acetovanillone inhibits the reaction [GPX1 protein affects the reaction [Phencyclidine affects the localization of NCF1 protein]]; acetovanillone inhibits the reaction [LEP protein results in increased expression of NCF1 protein]
acetovanillone inhibits the reaction [2,2',4,6,6'-pentachlorobiphenyl results in increased phosphorylation of NCF1 protein]; acetovanillone inhibits the reaction [2,3',4,4',5-pentachlorobiphenyl results in increased phosphorylation of NCF1 protein]; acetovanillone inhibits the reaction [2,4,5,2',4',5'-hexachlorobiphenyl results in increased phosphorylation of NCF1 protein]; acetovanillone inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased phosphorylation of NCF1 protein]; acetovanillone inhibits the reaction [arsenic trioxide affects the localization of NCF1 protein]; acetovanillone inhibits the reaction [Glucose results in increased expression of and results in increased activity of NCF1 protein]; acetovanillone inhibits the reaction [IL1B protein affects the localization of NCF1 protein]; acetovanillone inhibits the reaction [Lipopolysaccharides affects the localization of NCF1 protein]
acetovanillone inhibits the reaction [Hydrogen Peroxide results in increased expression of NCF1 mRNA]; acetovanillone inhibits the reaction [Hydrogen Peroxide results in increased expression of NCF1 protein]; acetovanillone inhibits the reaction [Palmitic Acid results in increased expression of NCF1 mRNA]
CTD PMID:16380530 PMID:18424721 PMID:19281832 PMID:19878672 PMID:20299304 More... NCBI chr12:22,485,382...22,494,647
Ensembl chr12:22,485,451...22,494,646
JBrowse link
G Ncf2 neutrophil cytosolic factor 2 multiple interactions ISO
EXP
acetovanillone inhibits the reaction [LEP protein results in increased expression of NCF2 protein]
acetovanillone inhibits the reaction [Palmitic Acid results in increased expression of NCF2 mRNA]
CTD PMID:16380530 PMID:24080574 NCBI chr13:64,955,502...64,986,289
Ensembl chr13:64,955,503...64,986,277
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions EXP
ISO
acetovanillone inhibits the reaction [Cisplatin results in increased expression of NFE2L2 mRNA]
[acetovanillone co-treated with AGT protein] results in increased expression of and affects the localization of NFE2L2 protein
CTD PMID:24291008 PMID:27983965 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO acetovanillone inhibits the reaction [Homocysteine results in increased phosphorylation of and results in increased activity of NFKBIA protein]
acetovanillone inhibits the reaction [[Maneb co-treated with Paraquat] results in increased phosphorylation of and results in decreased expression of NFKBIA protein]; acetovanillone inhibits the reaction [Glucose results in increased phosphorylation of NFKBIA protein]
CTD PMID:16845898 PMID:17065336 PMID:28202386 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions ISO acetovanillone inhibits the reaction [tetrachlorobenzoquinone results in increased expression of and results in decreased ubiquitination of NLRP3 protein] CTD PMID:26901245 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions EXP
ISO
acetovanillone inhibits the reaction [Ethanol results in increased expression of NOS2 protein]; acetovanillone inhibits the reaction [Formaldehyde results in increased expression of NOS2 mRNA]
acetovanillone inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of NOS2 mRNA]; acetovanillone inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of NOS2 mRNA]
CTD PMID:21983654 PMID:26522475 PMID:28202386 PMID:30797899 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nos3 nitric oxide synthase 3 multiple interactions
increases expression
ISO
EXP
acetovanillone inhibits the reaction [Glucose results in decreased expression of NOS3 protein]
[Cadmium co-treated with acetovanillone] results in increased expression of NOS3 protein; acetovanillone inhibits the reaction [Formaldehyde results in increased expression of NOS3 mRNA]
acetovanillone results in increased expression of NOS3 protein
CTD PMID:19878672 PMID:21983654 PMID:23703608 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
JBrowse link
G Nox1 NADPH oxidase 1 multiple interactions EXP
ISO
acetovanillone inhibits the reaction [Ethanol results in increased expression of NOX1 protein]; acetovanillone inhibits the reaction [Mitogens results in increased expression of NOX1 mRNA]; acetovanillone promotes the reaction [Thioctic Acid inhibits the reaction [Mitogens results in increased expression of NOX1 mRNA]]; Thioctic Acid promotes the reaction [acetovanillone inhibits the reaction [Mitogens results in increased expression of NOX1 mRNA]]
acetovanillone inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of NOX1 mRNA]
CTD PMID:26522475 PMID:29760339 PMID:30797899 NCBI chr  X:97,279,058...97,332,291
Ensembl chr  X:97,279,056...97,302,236
JBrowse link
G Nox4 NADPH oxidase 4 multiple interactions EXP [acetovanillone co-treated with CAT protein] inhibits the reaction [Cyclosporine results in increased expression of NOX4 mRNA]; acetovanillone inhibits the reaction [Cyclosporine results in increased expression of NOX4 mRNA]; acetovanillone inhibits the reaction [Ethanol results in increased expression of NOX4 protein]; acetovanillone inhibits the reaction [Mitogens results in increased expression of NOX4 mRNA]; acetovanillone promotes the reaction [Thioctic Acid inhibits the reaction [Mitogens results in increased expression of NOX4 mRNA]]; Thioctic Acid promotes the reaction [acetovanillone inhibits the reaction [Mitogens results in increased expression of NOX4 mRNA]] CTD PMID:26522475 PMID:29760339 PMID:32298299 NCBI chr 1:140,900,886...141,078,844
Ensembl chr 1:140,901,097...141,077,406
JBrowse link
G Noxa1 NADPH oxidase activator 1 multiple interactions EXP acetovanillone inhibits the reaction [Palmitic Acid results in increased expression of NOXA1 mRNA] CTD PMID:24080574 NCBI chr 3:7,895,488...7,907,011
Ensembl chr 3:7,895,488...7,905,967
JBrowse link
G Noxo1 NADPH oxidase organizer 1 multiple interactions EXP acetovanillone inhibits the reaction [Palmitic Acid results in increased expression of NOXO1 mRNA] CTD PMID:24080574 NCBI chr10:13,721,473...13,726,061
Ensembl chr10:13,721,473...13,726,061
JBrowse link
G Nphs2 NPHS2 stomatin family member, podocin multiple interactions ISO acetovanillone inhibits the reaction [Homocysteine results in decreased expression of NPHS2 mRNA]; acetovanillone inhibits the reaction [Homocysteine results in decreased expression of NPHS2 protein] CTD PMID:20036696 NCBI chr13:68,448,720...68,461,312
Ensembl chr13:68,448,926...68,461,313
JBrowse link
G Olr1 oxidized low density lipoprotein receptor 1 multiple interactions ISO acetovanillone inhibits the reaction [Glucose results in increased expression of OLR1 mRNA] CTD PMID:19878672 NCBI chr 4:162,926,436...162,949,057
Ensembl chr 4:162,926,439...162,948,523
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO
EXP
acetovanillone inhibits the reaction [AGT protein results in increased activity of PARP1 protein]; acetovanillone inhibits the reaction [zinc chloride results in increased activity of PARP1 protein]
[polyethylene glycol-superoxide dismutase co-treated with acetovanillone] inhibits the reaction [EDN1 protein results in increased expression of and results in increased cleavage of PARP1 protein]
acetovanillone inhibits the reaction [tert-Butylhydroperoxide results in increased cleavage of PARP1 protein]
CTD PMID:15502880 PMID:18509044 PMID:24932781 PMID:29111459 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions EXP acetovanillone inhibits the reaction [Ozone results in increased expression of PCNA protein] CTD PMID:9517619 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
JBrowse link
G Plcb1 phospholipase C beta 1 multiple interactions EXP acetovanillone inhibits the reaction [Glucose results in increased expression of PLCB1 protein]; acetovanillone inhibits the reaction [Streptozocin results in increased expression of PLCB1 protein] CTD PMID:20691780 NCBI chr 3:122,059,968...122,772,896
Ensembl chr 3:122,060,031...122,772,869
JBrowse link
G Plcb2 phospholipase C, beta 2 multiple interactions EXP acetovanillone inhibits the reaction [Glucose results in increased expression of PLCB2 protein]; acetovanillone inhibits the reaction [Streptozocin results in increased expression of PLCB2 protein] CTD PMID:20691780 NCBI chr 3:105,683,676...105,704,384
Ensembl chr 3:105,684,815...105,704,302
JBrowse link
G Pomc proopiomelanocortin multiple interactions EXP acetovanillone inhibits the reaction [POMC protein affects the abundance of F2-Isoprostanes] CTD PMID:16053986 NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664
JBrowse link
G Prkcd protein kinase C, delta multiple interactions ISO
EXP
acetovanillone inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin promotes the reaction [NCF1 protein binds to PRKCD protein]]; acetovanillone inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin promotes the reaction [PRKCD protein binds to HTR1A protein]]
acetovanillone analog inhibits the reaction [Chlorpyrifos results in increased cleavage of PRKCD protein]
CTD PMID:29859868 PMID:30366073 NCBI chr16:5,769,226...5,807,214
Ensembl chr16:5,769,215...5,799,352
JBrowse link
G Prkg1 protein kinase cGMP-dependent 1 multiple interactions EXP acetovanillone inhibits the reaction [Glucose results in decreased expression of PRKG1 protein] CTD PMID:17320767 NCBI chr 1:228,409,883...229,638,794 JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 multiple interactions EXP acetovanillone inhibits the reaction [Formaldehyde results in increased expression of PTGS1 mRNA]; acetovanillone inhibits the reaction [Streptozocin results in increased expression of PTGS1 protein] CTD PMID:18414395 PMID:21983654 NCBI chr 3:19,584,015...19,605,589
Ensembl chr 3:19,584,015...19,605,586
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
decreases expression
EXP
ISO
acetovanillone inhibits the reaction [AGT protein results in increased expression of PTGS2 protein]; acetovanillone inhibits the reaction [Ethanol results in increased expression of PTGS2 protein]; acetovanillone inhibits the reaction [Mercuric Chloride results in increased expression of PTGS2 mRNA]; acetovanillone inhibits the reaction [Streptozocin results in increased expression of PTGS2 protein]
acetovanillone inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin results in increased expression of PTGS2 protein]; acetovanillone inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of PTGS2 protein]; acetovanillone inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]
acetovanillone inhibits the reaction [2-aminodiphenyl results in increased expression of PTGS2 protein]; acetovanillone inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]; acetovanillone inhibits the reaction [Particulate Matter results in increased expression of PTGS2 mRNA]; acetovanillone inhibits the reaction [Particulate Matter results in increased expression of PTGS2 protein]
acetovanillone results in decreased expression of PTGS2 mRNA
CTD PMID:17244722 PMID:18414395 PMID:21983654 PMID:22288910 PMID:23415682 More... NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Ptk2b protein tyrosine kinase 2 beta multiple interactions EXP acetovanillone inhibits the reaction [TNF protein results in decreased phosphorylation of PTK2B protein] CTD PMID:23774252 NCBI chr15:40,360,722...40,481,235
Ensembl chr15:40,360,723...40,481,282
JBrowse link
G Pvalb parvalbumin multiple interactions ISO acetovanillone inhibits the reaction [Ketamine results in decreased expression of PVALB protein] CTD PMID:18063801 NCBI chr 7:109,772,939...109,787,954
Ensembl chr 7:109,772,593...109,784,561
JBrowse link
G Pycard PYD and CARD domain containing multiple interactions ISO acetovanillone inhibits the reaction [Ethanol results in increased expression of PYCARD protein] CTD PMID:26079697 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO
EXP
acetovanillone inhibits the reaction [[Maneb co-treated with Paraquat] results in increased phosphorylation of RELA protein]; acetovanillone inhibits the reaction [Cocaine results in increased phosphorylation of and results in increased activity of RELA protein]; acetovanillone inhibits the reaction [DMD gene mutant form results in increased expression of RELA protein modified form]; acetovanillone inhibits the reaction [TNF protein results in increased phosphorylation of RELA protein]
acetovanillone inhibits the reaction [IL1B promotes the reaction [EP300 protein binds to RELA protein]]; acetovanillone inhibits the reaction [IL1B protein results in increased expression of RELA protein modified form]
acetovanillone inhibits the reaction [RELA protein binds to MMP9 promoter]; acetovanillone inhibits the reaction [TNF protein affects the localization of RELA protein]
CTD PMID:19281832 PMID:19608869 PMID:20354174 PMID:23774252 PMID:26930420 More... NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Runx2 RUNX family transcription factor 2 multiple interactions EXP acetovanillone inhibits the reaction [Palmitic Acid results in increased expression of RUNX2 mRNA] CTD PMID:24080574 NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167
JBrowse link
G S100a4 S100 calcium-binding protein A4 multiple interactions ISO acetovanillone inhibits the reaction [Homocysteine results in increased expression of S100A4 protein] CTD PMID:21647593 NCBI chr 2:176,090,951...176,093,258
Ensembl chr 2:176,091,804...176,093,254
JBrowse link
G Sele selectin E multiple interactions ISO acetovanillone inhibits the reaction [tetrachlorobenzoquinone results in increased expression of SELE protein] CTD PMID:26901245 NCBI chr13:76,402,841...76,412,741
Ensembl chr13:76,403,304...76,412,741
JBrowse link
G Serpine1 serpin family E member 1 multiple interactions ISO acetovanillone inhibits the reaction [TNF protein results in increased expression of SERPINE1 mRNA] CTD PMID:22414048 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
JBrowse link
G Shc1 SHC adaptor protein 1 multiple interactions EXP acetovanillone inhibits the reaction [Oxygen deficiency results in increased expression of SHC1 mRNA]; acetovanillone inhibits the reaction [Oxygen deficiency results in increased expression of SHC1 protein] CTD PMID:23270704 NCBI chr 2:174,837,937...174,849,538
Ensembl chr 2:174,837,930...174,849,536
JBrowse link
G Sirt1 sirtuin 1 multiple interactions ISO acetovanillone inhibits the reaction [DMD gene mutant form results in increased expression of SIRT1 mRNA] CTD PMID:26930420 NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Slc40a1 solute carrier family 40 member 1 multiple interactions ISO acetovanillone inhibits the reaction [[Paraquat co-treated with Maneb] results in decreased expression of SLC40A1 protein] CTD PMID:30797899 NCBI chr 9:48,033,526...48,053,876
Ensembl chr 9:48,033,526...48,051,481
JBrowse link
G Snca synuclein alpha multiple interactions EXP acetovanillone analog inhibits the reaction [Chlorpyrifos results in increased phosphorylation of SNCA protein] CTD PMID:29859868 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions EXP
ISO
acetovanillone inhibits the reaction [[Desoxycorticosterone co-treated with Sodium Chloride] results in decreased expression of SOD1 protein]; acetovanillone inhibits the reaction [Formaldehyde results in increased expression of SOD1 mRNA]
acetovanillone inhibits the reaction [GPX1 protein affects the reaction [Phencyclidine results in increased activity of SOD1 protein]]
CTD PMID:21983654 PMID:22431579 PMID:29037473 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions EXP
ISO
acetovanillone inhibits the reaction [[Desoxycorticosterone co-treated with Sodium Chloride] results in decreased expression of SOD2 protein]; acetovanillone inhibits the reaction [Formaldehyde results in increased expression of SOD2 mRNA]
acetovanillone inhibits the reaction [GPX1 protein affects the reaction [Phencyclidine results in decreased activity of SOD2 protein]]
CTD PMID:21983654 PMID:22431579 PMID:29037473 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Star steroidogenic acute regulatory protein multiple interactions EXP acetovanillone inhibits the reaction [Hydrogen Peroxide deficiency results in decreased expression of STAR protein]; acetovanillone inhibits the reaction [Oxygen deficiency results in decreased expression of STAR mRNA]; acetovanillone inhibits the reaction [Oxygen deficiency results in decreased expression of STAR protein] CTD PMID:23270704 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672
JBrowse link
G Stat1 signal transducer and activator of transcription 1 multiple interactions ISO
EXP
acetovanillone inhibits the reaction [vanadium pentoxide results in increased phosphorylation of STAT1 protein]
acetovanillone analog inhibits the reaction [Chlorpyrifos results in increased expression of and results in increased phosphorylation of STAT1 protein]
CTD PMID:18322232 PMID:29859868 NCBI chr 9:49,419,561...49,459,969 JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP acetovanillone inhibits the reaction [Mitogens results in increased expression of TGFB1 protein] CTD PMID:29760339 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Th tyrosine hydroxylase decreases expression
multiple interactions
EXP acetovanillone results in decreased expression of TH mRNA
acetovanillone analog inhibits the reaction [Chlorpyrifos results in decreased expression of TH protein]
CTD PMID:25217652 PMID:29859868 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767
JBrowse link
G Tjp1 tight junction protein 1 multiple interactions ISO acetovanillone inhibits the reaction [2,2',4,6,6'-pentachlorobiphenyl results in decreased expression of TJP1 protein]; acetovanillone inhibits the reaction [2,3',4,4',5-pentachlorobiphenyl results in decreased expression of TJP1 protein]; acetovanillone inhibits the reaction [2,4,5,2',4',5'-hexachlorobiphenyl results in decreased expression of TJP1 protein]; acetovanillone inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TJP1 protein]
acetovanillone inhibits the reaction [Homocysteine results in decreased expression of TJP1 protein]
CTD PMID:20299304 PMID:21647593 NCBI chr 1:118,849,838...119,094,492
Ensembl chr 1:118,849,838...119,094,432
JBrowse link
G Tnf tumor necrosis factor multiple interactions
decreases response to substance
ISO
EXP
acetovanillone inhibits the reaction [tert-Butylhydroperoxide results in increased secretion of TNF protein]; acetovanillone inhibits the reaction [TNF protein results in increased abundance of Hydrogen Peroxide]; acetovanillone inhibits the reaction [TNF protein results in increased abundance of Superoxides]; acetovanillone inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of FN1 protein]; acetovanillone inhibits the reaction [TNF protein results in increased expression of CCL11 mRNA]; acetovanillone inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]; acetovanillone inhibits the reaction [TNF protein results in increased expression of CCL2 protein]; acetovanillone inhibits the reaction [TNF protein results in increased expression of CCL5 protein]; acetovanillone inhibits the reaction [TNF protein results in increased expression of CCL7 mRNA]; acetovanillone inhibits the reaction [TNF protein results in increased expression of CSF2 mRNA]; acetovanillone inhibits the reaction [TNF protein results in increased expression of CXCL1 mRNA]; acetovanillone inhibits the reaction [TNF protein results in increased expression of CXCL1 protein]; acetovanillone inhibits the reaction [TNF protein results in increased expression of CXCL10 mRNA]; acetovanillone inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA]; acetovanillone inhibits the reaction [TNF protein results in increased expression of CXCL8 protein]; acetovanillone inhibits the reaction [TNF protein results in increased expression of FN1 mRNA]; acetovanillone inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]; acetovanillone inhibits the reaction [TNF protein results in increased expression of IL6 mRNA]; acetovanillone inhibits the reaction [TNF protein results in increased expression of IL6 protein]; acetovanillone inhibits the reaction [TNF protein results in increased expression of MIF mRNA]; acetovanillone inhibits the reaction [TNF protein results in increased expression of MMP13 protein]; acetovanillone inhibits the reaction [TNF protein results in increased expression of SERPINE1 mRNA]; acetovanillone inhibits the reaction [TNF protein results in increased phosphorylation of MAPK1 protein]; acetovanillone inhibits the reaction [TNF protein results in increased phosphorylation of MAPK3 protein]
acetovanillone inhibits the reaction [Cisplatin results in increased expression of TNF protein]; acetovanillone inhibits the reaction [Ethanol results in increased expression of TNF protein]; acetovanillone inhibits the reaction [Mitogens results in increased expression of TNF protein]; acetovanillone inhibits the reaction [TNF protein affects the localization of RELA protein]; acetovanillone inhibits the reaction [TNF protein results in decreased phosphorylation of PTK2B protein]; acetovanillone inhibits the reaction [TNF protein results in increased abundance of Reactive Oxygen Species]; acetovanillone inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of MMP9 protein]; acetovanillone inhibits the reaction [TNF protein results in increased expression of MMP9 mRNA]; acetovanillone inhibits the reaction [TNF protein results in increased phosphorylation of MAPK1 protein]; acetovanillone inhibits the reaction [TNF protein results in increased phosphorylation of MAPK3 protein]; acetovanillone promotes the reaction [Thioctic Acid inhibits the reaction [Mitogens results in increased expression of TNF protein]]; Thioctic Acid promotes the reaction [acetovanillone inhibits the reaction [Mitogens results in increased expression of TNF protein]]
acetovanillone results in decreased susceptibility to TNF protein
acetovanillone inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of TNF mRNA]; acetovanillone inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of TNF mRNA]; acetovanillone inhibits the reaction [cobaltous chloride results in increased expression of TNF protein]; acetovanillone inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; acetovanillone inhibits the reaction [Pyruvaldehyde results in increased expression of TNF protein]; acetovanillone inhibits the reaction [TNF protein results in increased expression of CCL5 mRNA]; acetovanillone inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; acetovanillone inhibits the reaction [TNF protein results in increased phosphorylation of RELA protein]
CTD PMID:10495789 PMID:15795323 PMID:16632126 PMID:19608869 PMID:21211511 More... NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tp53 tumor protein p53 multiple interactions EXP acetovanillone inhibits the reaction [[Desoxycorticosterone co-treated with Sodium Chloride] results in increased expression of TP53 protein] CTD PMID:22431579 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions ISO acetovanillone inhibits the reaction [2,4,5,2',4',5'-hexachlorobiphenyl results in increased expression of VCAM1 protein]; acetovanillone inhibits the reaction [IL1B protein results in increased expression of VCAM1 mRNA]; acetovanillone inhibits the reaction [IL1B protein results in increased expression of VCAM1 protein]; acetovanillone inhibits the reaction [tetrachlorobenzoquinone results in increased expression of VCAM1 protein] CTD PMID:19281832 PMID:19632255 PMID:26901245 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
JBrowse link
G Xdh xanthine dehydrogenase multiple interactions EXP acetovanillone inhibits the reaction [Cocaine results in increased activity of XDH protein] CTD PMID:17217956 NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268
JBrowse link
butan-2-one term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacng6 calcium voltage-gated channel auxiliary subunit gamma 6 decreases expression ISO methylethyl ketone results in decreased expression of CACNG6 mRNA CTD PMID:33064461 NCBI chr 1:65,732,910...65,747,377
Ensembl chr 1:65,732,632...65,747,341
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 affects response to substance ISO CYP2E1 gene mutant form affects the susceptibility to methylethyl ketone CTD PMID:21352904 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Glud1 glutamate dehydrogenase 1 multiple interactions ISO
EXP
methylethyl ketone promotes the reaction [2-dichlorobenzene results in increased activity of GLUD1 protein] CTD PMID:2554539 NCBI chr16:9,640,312...9,673,961
Ensembl chr16:9,640,312...9,673,957
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha increases expression ISO methylethyl ketone results in increased expression of PPARGC1A mRNA CTD PMID:33064461 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
JBrowse link
G Srsf2 serine and arginine rich splicing factor 2 decreases expression ISO methylethyl ketone results in decreased expression of SRSF2 mRNA CTD PMID:33064461 NCBI chr10:102,052,158...102,055,365
Ensembl chr10:102,052,314...102,055,338
JBrowse link
buten-2-one term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G App amyloid beta precursor protein multiple interactions ISO [3-buten-2-one results in increased metabolism of APP protein] which results in increased secretion of APP protein modified form CTD PMID:29618714 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase multiple interactions ISO 3-buten-2-one binds to and results in decreased activity of GAPDH protein CTD PMID:22084934 NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235
JBrowse link
G Ptgr1 prostaglandin reductase 1 multiple interactions EXP [PTGR1 protein co-treated with NADP] affects the reduction of 3-buten-2-one CTD PMID:11524419 NCBI chr 5:73,784,000...73,802,624
Ensembl chr 5:73,784,009...73,802,666
JBrowse link
heptan-2-one term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gna15 G protein subunit alpha 15 increases response to substance
multiple interactions
ISO GNA15 protein results in increased susceptibility to 2-heptanone
[GNA15 protein results in increased susceptibility to 2-heptanone] which results in decreased activity of OLFR154 protein
CTD PMID:15598656 NCBI chr 7:8,184,632...8,205,508
Ensembl chr 7:8,184,861...8,205,508
JBrowse link
G Gnal G protein subunit alpha L multiple interactions
increases response to substance
ISO [GNAL protein results in increased susceptibility to 2-heptanone] which results in increased activity of OLFR154 protein CTD PMID:15598656 NCBI chr18:60,622,311...60,762,599
Ensembl chr18:60,622,311...60,762,599
JBrowse link
G Gstp1 glutathione S-transferase pi 1 decreases activity ISO 2-heptanone results in decreased activity of GSTP1 protein CTD PMID:18409811 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link
iloperidone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 decreases activity ISO iloperidone results in decreased activity of ABCB11 protein CTD PMID:23956101 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 decreases activity
decreases expression
ISO iloperidone results in decreased activity of CYP3A4 protein
iloperidone results in decreased expression of CYP3A4 mRNA
CTD PMID:32941854 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
mono(2-ethyl-5-oxohexyl) phthalate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam33 ADAM metallopeptidase domain 33 multiple interactions ISO [[Endocrine Disruptors results in increased abundance of mono(2-ethyl-5-oxohexyl)phthalate] which results in increased methylation of ADAM33 intron] which results in increased expression of ADAM33 mRNA CTD PMID:30226539 NCBI chr 3:118,262,395...118,283,461
Ensembl chr 3:118,271,029...118,283,461
JBrowse link
G Crp C-reactive protein decreases expression ISO mono(2-ethyl-5-oxohexyl)phthalate results in decreased expression of CRP protein CTD PMID:21349512 NCBI chr13:85,131,635...85,175,179
Ensembl chr13:85,124,977...85,175,178
JBrowse link
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 multiple interactions ISO
EXP
[CYP2C19 protein results in increased metabolism of mono-(2-ethylhexyl)phthalate] which results in increased chemical synthesis of mono(2-ethyl-5-oxohexyl)phthalate
[CYP2C6V1 protein results in increased metabolism of mono-(2-ethylhexyl)phthalate] which results in increased chemical synthesis of mono(2-ethyl-5-oxohexyl)phthalate
CTD PMID:22186153 PMID:23545481 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions EXP
ISO
[CYP3A2 protein results in increased metabolism of mono-(2-ethylhexyl)phthalate] which results in increased chemical synthesis of mono(2-ethyl-5-oxohexyl)phthalate
[CYP3A4 protein results in increased metabolism of mono-(2-ethylhexyl)phthalate] which results in increased chemical synthesis of mono(2-ethyl-5-oxohexyl)phthalate
CTD PMID:23545481 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Flg filaggrin multiple interactions ISO [FLG gene polymorphism affects the susceptibility to Diethylhexyl Phthalate] which affects the abundance of mono(2-ethyl-5-oxohexyl)phthalate CTD PMID:24380925 NCBI chr 2:178,888,688...178,912,731 JBrowse link
G Mirlet7c1 microRNA let-7c-1 multiple interactions ISO [Diethylhexyl Phthalate results in increased abundance of mono(2-ethyl-5-oxohexyl)phthalate] which affects the expression of MIRLET7C CTD PMID:30481674 NCBI chr11:16,201,163...16,201,256
Ensembl chr11:16,201,158...16,201,265
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha increases activity ISO mono(2-ethyl-5-oxohexyl)phthalate results in increased activity of PPARA protein CTD PMID:28571686 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO mono(2-ethyl-5-oxohexyl)phthalate binds to and affects the folding of and results in increased activity of PPARG protein CTD PMID:30085373 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Shbg sex hormone binding globulin decreases secretion ISO mono(2-ethyl-5-oxohexyl)phthalate results in decreased secretion of SHBG protein CTD PMID:24945889 NCBI chr10:54,332,939...54,350,409
Ensembl chr10:54,332,941...54,351,057
JBrowse link
nabumetone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl2 BCL2, apoptosis regulator decreases expression ISO nabumetone results in decreased expression of BCL2 protein CTD PMID:16019514 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression ISO nabumetone results in increased expression of FOS mRNA CTD PMID:12730611 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity ISO nabumetone results in increased activity of NR1I2 protein CTD PMID:25455453 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 decreases activity EXP nabumetone metabolite results in decreased activity of PTGS1 protein CTD PMID:9258749 NCBI chr 3:19,584,015...19,605,589
Ensembl chr 3:19,584,015...19,605,586
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases activity EXP nabumetone metabolite results in decreased activity of PTGS2 protein CTD PMID:9258749 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Sell selectin L affects expression ISO nabumetone affects the expression of SELL protein CTD PMID:12147693 NCBI chr13:76,416,969...76,436,444
Ensembl chr13:76,416,915...76,436,456
JBrowse link
G Utrn utrophin increases expression ISO nabumetone results in increased expression of UTRN mRNA; nabumetone results in increased expression of UTRN protein CTD PMID:22028826 NCBI chr 1:6,720,854...7,224,313
Ensembl chr 1:6,722,594...7,224,313
JBrowse link
pentane-2,3-dione term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam10 ADAM metallopeptidase domain 10 increases expression EXP 2,3-pentanedione results in increased expression of ADAM10 mRNA CTD PMID:25710175 NCBI chr 8:71,346,008...71,477,889
Ensembl chr 8:71,345,837...71,477,889
JBrowse link
G Adam19 ADAM metallopeptidase domain 19 increases expression EXP 2,3-pentanedione results in increased expression of ADAM19 mRNA CTD PMID:25710175 NCBI chr10:30,491,362...30,583,115
Ensembl chr10:30,491,405...30,583,105
JBrowse link
G Adam8 ADAM metallopeptidase domain 8 decreases expression EXP 2,3-pentanedione results in decreased expression of ADAM8 mRNA CTD PMID:25710175 NCBI chr 1:194,776,559...194,789,330
Ensembl chr 1:194,770,060...194,788,801
JBrowse link
G Akap5 A-kinase anchoring protein 5 increases expression EXP 2,3-pentanedione results in increased expression of AKAP5 mRNA CTD PMID:25710175 NCBI chr 6:95,051,527...95,061,075
Ensembl chr 6:95,051,537...95,061,578
JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B increases reduction
multiple interactions
ISO AKR1B1 protein results in increased reduction of 2,3-pentanedione
[AKR1B1 protein results in increased reduction of 2,3-pentanedione] which results in increased chemical synthesis of Pentanones
CTD PMID:23295224 NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157
JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 increases reduction
multiple interactions
ISO AKR1B10 protein results in increased reduction of 2,3-pentanedione
[AKR1B10 protein results in increased reduction of 2,3-pentanedione] which results in increased chemical synthesis of Pentanones
CTD PMID:23295224 NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852
JBrowse link
G Akr1b8 aldo-keto reductase family 1, member B8 multiple interactions EXP [AKR1B8 protein co-treated with NADP] affects the reduction of 2,3-pentanedione CTD PMID:18845131 NCBI chr 4:62,997,241...63,009,815 JBrowse link
G Aldh1a3 aldehyde dehydrogenase 1 family, member A3 increases expression ISO 2,3-pentanedione results in increased expression of ALDH1A3 mRNA CTD PMID:30710127 NCBI chr 1:119,982,272...120,017,416
Ensembl chr 1:119,982,277...120,017,436
JBrowse link
G Angptl4 angiopoietin-like 4 increases expression EXP 2,3-pentanedione results in increased expression of ANGPTL4 mRNA CTD PMID:25710175 NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519
JBrowse link
G Apln apelin increases expression EXP 2,3-pentanedione results in increased expression of APLN mRNA CTD PMID:25710175 NCBI chr  X:127,180,801...127,213,567
Ensembl chr  X:127,203,823...127,213,391
JBrowse link
G Arhgap17 Rho GTPase activating protein 17 increases expression EXP 2,3-pentanedione results in increased expression of ARHGAP17 mRNA CTD PMID:25710175 NCBI chr 1:177,807,579...177,897,027
Ensembl chr 1:177,807,583...177,896,854
JBrowse link
G Bcat1 branched chain amino acid transaminase 1 increases expression EXP 2,3-pentanedione results in increased expression of BCAT1 mRNA CTD PMID:25710175 NCBI chr 4:177,964,834...178,046,573
Ensembl chr 4:177,964,834...178,046,597
JBrowse link
G Bmp3 bone morphogenetic protein 3 decreases expression EXP 2,3-pentanedione results in decreased expression of BMP3 mRNA CTD PMID:25710175 NCBI chr14:10,712,489...10,737,153
Ensembl chr14:10,712,489...10,737,153
JBrowse link
G C9 complement C9 decreases expression EXP 2,3-pentanedione results in decreased expression of C9 mRNA CTD PMID:25710175 NCBI chr 2:55,573,094...55,621,345
Ensembl chr 2:55,572,992...55,621,338
JBrowse link
G Cc2d2a coiled-coil and C2 domain containing 2A decreases expression ISO 2,3-pentanedione results in decreased expression of CC2D2A mRNA CTD PMID:30710127 NCBI chr14:67,349,004...67,435,883
Ensembl chr14:67,351,353...67,435,949
JBrowse link
G Ccn2 cellular communication network factor 2 increases expression EXP 2,3-pentanedione results in increased expression of CCN2 mRNA CTD PMID:25710175 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734
JBrowse link
G Ccn4 cellular communication network factor 4 increases expression EXP 2,3-pentanedione results in increased expression of CCN4 mRNA CTD PMID:25710175 NCBI chr 7:98,645,238...98,677,253
Ensembl chr 7:98,645,182...98,677,248
JBrowse link
G Cd36 CD36 molecule increases expression EXP 2,3-pentanedione results in increased expression of CD36 mRNA CTD PMID:25710175 NCBI chr 4:17,317,343...17,410,084 JBrowse link
G Cdc20b cell division cycle 20B decreases expression ISO 2,3-pentanedione results in decreased expression of CDC20B mRNA CTD PMID:30710127 NCBI chr 2:44,688,349...44,738,056 JBrowse link
G Cdhr4 cadherin-related family member 4 decreases expression EXP 2,3-pentanedione results in decreased expression of CDHR4 mRNA CTD PMID:25710175 NCBI chr 8:108,682,594...108,690,358 JBrowse link
G Ces1d carboxylesterase 1D decreases expression EXP 2,3-pentanedione results in decreased expression of CES1D mRNA CTD PMID:25710175 NCBI chr19:13,873,490...13,912,035 JBrowse link
G Cfap221 cilia and flagella associated protein 221 decreases expression ISO 2,3-pentanedione results in decreased expression of CFAP221 mRNA CTD PMID:30710127 NCBI chr13:31,046,550...31,118,141
Ensembl chr13:31,046,535...31,116,899
JBrowse link
G Cfap70 cilia and flagella associated protein 70 decreases expression ISO 2,3-pentanedione results in decreased expression of CFAP70 mRNA CTD PMID:30710127 NCBI chr15:3,852,381...3,918,036
Ensembl chr15:3,852,509...3,918,014
JBrowse link
G Cldn18 claudin 18 increases expression EXP 2,3-pentanedione results in increased expression of CLDN18 mRNA CTD PMID:25710175 NCBI chr 8:100,246,499...100,265,797
Ensembl chr 8:100,247,633...100,273,351
JBrowse link
G Clic5 chloride intracellular channel 5 increases expression EXP 2,3-pentanedione results in increased expression of CLIC5 mRNA CTD PMID:25710175 NCBI chr 9:16,710,980...16,813,427
Ensembl chr 9:16,710,980...16,813,427
JBrowse link
G Cma1 chymase 1 increases expression EXP 2,3-pentanedione results in increased expression of CMA1 mRNA CTD PMID:25710175 NCBI chr15:29,417,451...29,420,233
Ensembl chr15:29,417,451...29,420,233
JBrowse link
G Col12a1 collagen type XII alpha 1 chain increases expression EXP 2,3-pentanedione results in increased expression of COL12A1 mRNA CTD PMID:25710175 NCBI chr 8:80,547,592...80,665,665
Ensembl chr 8:80,547,593...80,665,686
JBrowse link
G Col13a1 collagen type XIII alpha 1 chain decreases expression EXP 2,3-pentanedione results in decreased expression of COL13A1 mRNA CTD PMID:25710175 NCBI chr20:29,783,965...29,924,116
Ensembl chr20:29,783,965...29,924,032
JBrowse link
G Col14a1 collagen type XIV alpha 1 chain increases expression EXP 2,3-pentanedione results in increased expression of COL14A1 mRNA CTD PMID:25710175 NCBI chr 7:86,722,093...86,937,215
Ensembl chr 7:86,722,094...86,937,214
JBrowse link
G Col18a1 collagen type XVIII alpha 1 chain increases expression EXP 2,3-pentanedione results in increased expression of COL18A1 mRNA CTD PMID:25710175 NCBI chr20:11,474,104...11,582,593
Ensembl chr20:11,474,104...11,582,593
JBrowse link
G Col1a2 collagen type I alpha 2 chain increases expression EXP 2,3-pentanedione results in increased expression of COL1A2 mRNA CTD PMID:25710175 NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867
JBrowse link
G Col4a1 collagen type IV alpha 1 chain increases expression EXP 2,3-pentanedione results in increased expression of COL4A1 mRNA CTD PMID:25710175 NCBI chr16:78,183,533...78,294,412
Ensembl chr16:78,183,533...78,294,412
JBrowse link
G Col5a1 collagen type V alpha 1 chain increases expression EXP 2,3-pentanedione results in increased expression of COL5A1 mRNA CTD PMID:25710175 NCBI chr 3:11,208,429...11,356,715
Ensembl chr 3:11,208,512...11,354,588
JBrowse link
G Col5a2 collagen type V alpha 2 chain increases expression EXP 2,3-pentanedione results in increased expression of COL5A2 mRNA CTD PMID:25710175 NCBI chr 9:47,448,736...47,598,396
Ensembl chr 9:47,448,736...47,598,154
JBrowse link
G Col5a3 collagen type V alpha 3 chain increases expression EXP 2,3-pentanedione results in increased expression of COL5A3 mRNA CTD PMID:25710175 NCBI chr 8:19,304,564...19,349,809
Ensembl chr 8:19,304,571...19,349,853
JBrowse link
G Col6a2 collagen type VI alpha 2 chain increases expression EXP 2,3-pentanedione results in increased expression of COL6A2 mRNA CTD PMID:25710175 NCBI chr20:12,021,676...12,049,425
Ensembl chr20:12,021,767...12,057,564
JBrowse link
G Cpxm2 carboxypeptidase X (M14 family), member 2 decreases expression ISO 2,3-pentanedione results in decreased expression of CPXM2 mRNA CTD PMID:30710127 NCBI chr 1:186,836,797...186,947,222
Ensembl chr 1:186,836,797...186,947,220
JBrowse link
G Crabp2 cellular retinoic acid binding protein 2 increases expression EXP 2,3-pentanedione results in increased expression of CRABP2 mRNA CTD PMID:25710175 NCBI chr 2:173,417,004...173,421,352
Ensembl chr 2:173,416,857...173,421,379
JBrowse link
G Csf3 colony stimulating factor 3 decreases expression ISO 2,3-pentanedione results in decreased expression of CSF3 mRNA CTD PMID:30710127 NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603
JBrowse link
G Cthrc1 collagen triple helix repeat containing 1 increases expression EXP 2,3-pentanedione results in increased expression of CTHRC1 mRNA CTD PMID:25710175 NCBI chr 7:70,122,474...70,132,756
Ensembl chr 7:70,122,474...70,132,756
JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 increases expression EXP 2,3-pentanedione results in increased expression of CX3CR1 mRNA CTD PMID:25710175 NCBI chr 8:119,785,726...119,799,431
Ensembl chr 8:119,782,595...119,800,014
JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 decreases expression EXP 2,3-pentanedione results in decreased expression of CXCL1 mRNA CTD PMID:25710175 NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 decreases expression EXP 2,3-pentanedione results in decreased expression of CXCL3 mRNA CTD PMID:25710175 NCBI chr14:17,270,146...17,289,458
Ensembl chr14:17,270,146...17,289,511
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 decreases expression
increases expression
EXP 2,3-pentanedione results in decreased expression of CXCR4 mRNA
2,3-pentanedione results in increased expression of CXCR4 mRNA
CTD PMID:25710175 NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
JBrowse link
G Cyp2a3 cytochrome P450, family 2, subfamily a, polypeptide 3 decreases expression EXP 2,3-pentanedione results in decreased expression of CYP2A3 mRNA CTD PMID:25710175 NCBI chr 1:82,171,914...82,179,980
Ensembl chr 1:82,169,949...82,179,979
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 decreases expression EXP 2,3-pentanedione results in decreased expression of CYP2B1 mRNA CTD PMID:25710175 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
JBrowse link
G Cyp2f4 cytochrome P450, family 2, subfamily f, polypeptide 4 decreases expression EXP 2,3-pentanedione results in decreased expression of CYP2F4 mRNA CTD PMID:25710175 NCBI chr 1:82,416,108...82,429,897
Ensembl chr 1:82,416,130...82,429,896
JBrowse link
G Cyp4b1 cytochrome P450, family 4, subfamily b, polypeptide 1 decreases expression EXP 2,3-pentanedione results in decreased expression of CYP4B1 mRNA CTD PMID:25710175 NCBI chr 5:129,139,019...129,176,860
Ensembl chr 5:129,139,038...129,156,348
JBrowse link
G Dhrs9 dehydrogenase/reductase 9 increases expression ISO 2,3-pentanedione results in increased expression of DHRS9 mRNA CTD PMID:30710127 NCBI chr 3:54,147,834...54,170,052
Ensembl chr 3:54,147,803...54,220,241
JBrowse link
G Dmrt2 doublesex and mab-3 related transcription factor 2 decreases expression EXP 2,3-pentanedione results in decreased expression of DMRT2 mRNA CTD PMID:25710175 NCBI chr 1:223,317,543...223,324,131
Ensembl chr 1:223,317,642...223,324,131
JBrowse link
G Dnaaf1 dynein, axonemal, assembly factor 1 decreases expression ISO 2,3-pentanedione results in decreased expression of DNAAF1 mRNA CTD PMID:30710127 NCBI chr19:47,624,534...47,652,314
Ensembl chr19:47,624,181...47,652,313
JBrowse link
G Dnah12 dynein, axonemal, heavy chain 12 decreases expression ISO 2,3-pentanedione results in decreased expression of DNAH12 mRNA CTD PMID:30710127 NCBI chr16:1,936,354...2,092,663
Ensembl chr16:1,937,817...2,092,664
JBrowse link
G Dnah3 dynein, axonemal, heavy chain 3 decreases expression ISO 2,3-pentanedione results in decreased expression of DNAH3 mRNA CTD PMID:30710127 NCBI chr 1:174,305,929...174,479,490 JBrowse link
G Dnah6 dynein, axonemal, heavy chain 6 decreases expression ISO 2,3-pentanedione results in decreased expression of DNAH6 mRNA CTD PMID:30710127 NCBI chr 4:105,064,123...105,284,361
Ensembl chr 4:105,064,125...105,284,376
JBrowse link
G Dnai1 dynein, axonemal, intermediate chain 1 decreases expression ISO 2,3-pentanedione results in decreased expression of DNAI1 mRNA CTD PMID:30710127 NCBI chr 5:56,730,179...56,800,926
Ensembl chr 5:56,730,179...56,800,925
JBrowse link
G Egfr epidermal growth factor receptor increases expression EXP 2,3-pentanedione results in increased expression of EGFR mRNA CTD PMID:25710175 NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Egr2 early growth response 2 increases expression EXP 2,3-pentanedione results in increased expression of EGR2 mRNA CTD PMID:25710175 NCBI chr20:21,051,270...21,056,322
Ensembl chr20:21,051,277...21,055,562
JBrowse link
G Fbln1 fibulin 1 decreases expression EXP 2,3-pentanedione results in decreased expression of FBLN1 mRNA CTD PMID:25710175 NCBI chr 7:116,310,582...116,390,075
Ensembl chr 7:116,310,582...116,390,075
JBrowse link
G Fbn1 fibrillin 1 increases expression EXP 2,3-pentanedione results in increased expression of FBN1 mRNA CTD PMID:25710175 NCBI chr 3:112,554,257...112,750,835
Ensembl chr 3:112,554,925...112,750,889
JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 decreases expression EXP 2,3-pentanedione results in decreased expression of FGFR2 mRNA CTD PMID:25710175 NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626
JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 decreases expression EXP 2,3-pentanedione results in decreased expression of FGFR3 mRNA CTD PMID:25710175 NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341
JBrowse link
G Fmo2 flavin containing dimethylaniline monoxygenase 2 decreases expression EXP 2,3-pentanedione results in decreased expression of FMO2 mRNA CTD PMID:25710175 NCBI chr13:75,221,149...75,244,377
Ensembl chr13:75,224,402...75,244,308
JBrowse link
G Fn1 fibronectin 1 increases expression EXP 2,3-pentanedione results in increased expression of FN1 mRNA CTD PMID:25710175 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
JBrowse link
G Fndc3b fibronectin type III domain containing 3B decreases expression EXP 2,3-pentanedione results in decreased expression of FNDC3B mRNA CTD PMID:25710175 NCBI chr 2:110,311,439...110,617,504
Ensembl chr 2:110,312,694...110,547,830
JBrowse link
G Gad1 glutamate decarboxylase 1 decreases expression EXP 2,3-pentanedione results in decreased expression of GAD1 mRNA CTD PMID:25710175 NCBI chr 3:55,369,704...55,410,335
Ensembl chr 3:55,369,704...55,410,333
JBrowse link
G Gas6 growth arrest specific 6 increases expression EXP 2,3-pentanedione results in increased expression of GAS6 mRNA CTD PMID:25710175 NCBI chr16:76,045,430...76,075,904
Ensembl chr16:76,045,426...76,075,904
JBrowse link
G Ghitm growth hormone inducible transmembrane protein decreases expression EXP 2,3-pentanedione results in decreased expression of GHITM mRNA CTD PMID:25710175 NCBI chr16:12,885,551...12,897,887
Ensembl chr16:12,885,553...12,897,879
JBrowse link
G Gpr155 G protein-coupled receptor 155 decreases expression EXP 2,3-pentanedione results in decreased expression of GPR155 mRNA CTD PMID:25710175 NCBI chr 3:58,216,422...58,270,350
Ensembl chr 3:58,216,423...58,270,275
JBrowse link
G Gpx2 glutathione peroxidase 2 increases expression ISO 2,3-pentanedione results in increased expression of GPX2 mRNA CTD PMID:30710127 NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877
JBrowse link
G Grb10 growth factor receptor bound protein 10 increases expression EXP 2,3-pentanedione results in increased expression of GRB10 mRNA CTD PMID:25710175 NCBI chr14:86,495,054...86,602,815
Ensembl chr14:86,495,054...86,602,806
JBrowse link
G Gsta5 glutathione S-transferase alpha 5 decreases expression EXP 2,3-pentanedione results in decreased expression of GSTA5 mRNA CTD PMID:25710175 NCBI chr 8:79,105,561...79,117,472
Ensembl chr 8:79,105,661...79,117,472
JBrowse link
G Hap1 huntingtin-associated protein 1 decreases expression EXP 2,3-pentanedione results in decreased expression of HAP1 mRNA CTD PMID:25710175 NCBI chr10:85,277,890...85,286,126
Ensembl chr10:85,277,890...85,286,126
JBrowse link
G Has2 hyaluronan synthase 2 increases expression EXP 2,3-pentanedione results in increased expression of HAS2 mRNA CTD PMID:25710175 NCBI chr 7:88,113,326...88,139,337
Ensembl chr 7:88,113,326...88,128,933
JBrowse link
G Hbegf heparin-binding EGF-like growth factor increases expression EXP 2,3-pentanedione results in increased expression of HBEGF mRNA CTD PMID:25710175 NCBI chr18:28,106,284...28,116,167
Ensembl chr18:28,105,760...28,116,441
JBrowse link
G Hdac10 histone deacetylase 10 increases expression EXP 2,3-pentanedione results in increased expression of HDAC10 mRNA CTD PMID:25710175 NCBI chr 7:120,199,126...120,205,850
Ensembl chr 7:120,199,129...120,204,228
JBrowse link
G Igf1 insulin-like growth factor 1 increases expression EXP 2,3-pentanedione results in increased expression of IGF1 mRNA CTD PMID:25710175 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Igf2bp2 insulin-like growth factor 2 mRNA binding protein 2 increases expression EXP 2,3-pentanedione results in increased expression of IGF2BP2 mRNA CTD PMID:25710175 NCBI chr11:78,874,402...78,974,392
Ensembl chr11:78,874,414...78,974,377
JBrowse link
G Igfbp4 insulin-like growth factor binding protein 4 increases expression EXP 2,3-pentanedione results in increased expression of IGFBP4 mRNA CTD PMID:25710175 NCBI chr10:83,995,253...84,007,272
Ensembl chr10:83,989,591...84,007,225
JBrowse link
G Igfbp5 insulin-like growth factor binding protein 5 decreases expression EXP 2,3-pentanedione results in decreased expression of IGFBP5 mRNA CTD PMID:25710175 NCBI chr 9:74,452,371...74,464,953
Ensembl chr 9:74,448,382...74,465,156
JBrowse link
G Il18 interleukin 18 increases expression EXP 2,3-pentanedione results in increased expression of IL18 mRNA CTD PMID:25710175 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
JBrowse link
G Il1a interleukin 1 alpha increases expression EXP 2,3-pentanedione results in increased expression of IL1A mRNA CTD PMID:25710175 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Il1rn interleukin 1 receptor antagonist increases expression EXP 2,3-pentanedione results in increased expression of IL1RN mRNA CTD PMID:25710175 NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445
JBrowse link
G Il24 interleukin 24 increases expression EXP 2,3-pentanedione results in increased expression of IL24 mRNA CTD PMID:25710175 NCBI chr13:42,353,089...42,358,487
Ensembl chr13:42,353,090...42,358,487
JBrowse link
G Il33 interleukin 33 increases expression
decreases expression
EXP
ISO
2,3-pentanedione results in increased expression of IL33 mRNA
2,3-pentanedione results in decreased expression of IL33 mRNA
CTD PMID:25710175 PMID:30710127 NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373
JBrowse link
G Inhba inhibin subunit beta A increases expression EXP 2,3-pentanedione results in increased expression of INHBA mRNA CTD PMID:25710175 NCBI chr17:49,091,635...49,111,573
Ensembl chr17:49,095,920...49,108,982
JBrowse link
G Irak1bp1 interleukin-1 receptor-associated kinase 1 binding protein 1 decreases expression EXP 2,3-pentanedione results in decreased expression of IRAK1BP1 mRNA CTD PMID:25710175 NCBI chr 8:83,731,512...83,748,289
Ensembl chr 8:83,731,507...83,748,289
JBrowse link
G Itga5 integrin subunit alpha 5 increases expression EXP 2,3-pentanedione results in increased expression of ITGA5 mRNA CTD PMID:25710175 NCBI chr 7:134,478,963...134,502,837
Ensembl chr 7:134,478,968...134,502,837
JBrowse link
G Itga6 integrin subunit alpha 6 increases expression EXP 2,3-pentanedione results in increased expression of ITGA6 mRNA CTD PMID:25710175 NCBI chr 3:56,604,512...56,689,428
Ensembl chr 3:56,617,268...56,689,428
JBrowse link
G Itgb1 integrin subunit beta 1 increases expression EXP 2,3-pentanedione results in increased expression of ITGB1 mRNA CTD PMID:25710175 NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195
JBrowse link
G Itgb3 integrin subunit beta 3 increases expression EXP 2,3-pentanedione results in increased expression of ITGB3 mRNA CTD PMID:25710175 NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679
JBrowse link
G Klhl38 kelch-like family member 38 decreases expression EXP 2,3-pentanedione results in decreased expression of KLHL38 mRNA CTD PMID:25710175 NCBI chr 7:89,854,015...89,864,352
Ensembl chr 7:89,855,148...89,864,276
JBrowse link
G Krt13 keratin 13 increases expression ISO 2,3-pentanedione results in increased expression of KRT13 mRNA CTD PMID:30710127 NCBI chr10:85,052,122...85,056,032
Ensembl chr10:85,051,889...85,056,084
JBrowse link
G Krt14 keratin 14 increases expression ISO 2,3-pentanedione results in increased expression of KRT14 mRNA CTD PMID:30710127 NCBI chr10:85,137,932...85,141,990
Ensembl chr10:85,066,802...85,171,799
JBrowse link
G Krt16 keratin 16 increases expression ISO 2,3-pentanedione results in increased expression of KRT16 mRNA CTD PMID:30710127 NCBI chr10:85,168,357...85,171,744 JBrowse link
G Krt4 keratin 4 increases expression ISO 2,3-pentanedione results in increased expression of KRT4 mRNA CTD PMID:30710127 NCBI chr 7:133,046,067...133,052,027
Ensembl chr 7:133,046,515...133,052,019
JBrowse link
G Lamb3 laminin subunit beta 3 increases expression EXP 2,3-pentanedione results in increased expression of LAMB3 mRNA CTD PMID:25710175 NCBI chr13:104,833,810...104,875,405
Ensembl chr13:104,833,873...104,875,405
JBrowse link
G Lamc2 laminin subunit gamma 2 increases expression EXP 2,3-pentanedione results in increased expression of LAMC2 mRNA CTD PMID:25710175 NCBI chr13:65,284,664...65,344,200
Ensembl chr13:65,284,664...65,344,200
JBrowse link
G Lamc3 laminin subunit gamma 3 decreases expression EXP 2,3-pentanedione results in decreased expression of LAMC3 mRNA CTD PMID:25710175 NCBI chr 3:15,165,220...15,226,697
Ensembl chr 3:15,165,220...15,226,697
JBrowse link
G Lgi1 leucine-rich, glioma inactivated 1 decreases expression EXP 2,3-pentanedione results in decreased expression of LGI1 mRNA CTD PMID:25710175 NCBI chr 1:236,043,376...236,084,270
Ensembl chr 1:236,042,954...236,084,616
JBrowse link
G Lox lysyl oxidase increases expression EXP 2,3-pentanedione results in increased expression of LOX mRNA CTD PMID:25710175 NCBI chr18:45,964,311...46,041,477
Ensembl chr18:45,967,343...46,041,477
JBrowse link
G Loxl2 lysyl oxidase-like 2 increases expression EXP 2,3-pentanedione results in increased expression of LOXL2 mRNA CTD PMID:25710175 NCBI chr15:44,683,449...44,773,067
Ensembl chr15:44,683,880...44,773,067
JBrowse link
G Lrp10 LDL receptor related protein 10 increases expression EXP 2,3-pentanedione results in increased expression of LRP10 mRNA CTD PMID:25710175 NCBI chr15:27,921,105...27,927,507
Ensembl chr15:27,920,259...27,927,505
JBrowse link
G Mmp14 matrix metallopeptidase 14 increases expression EXP 2,3-pentanedione results in increased expression of MMP14 mRNA CTD PMID:25710175 NCBI chr15:27,887,795...27,897,020
Ensembl chr15:27,887,727...27,899,864
JBrowse link
G Mmp2 matrix metallopeptidase 2 increases expression EXP 2,3-pentanedione results in increased expression of MMP2 mRNA CTD PMID:25710175 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Mmp24 matrix metallopeptidase 24 decreases expression EXP 2,3-pentanedione results in decreased expression of MMP24 mRNA CTD PMID:25710175 NCBI chr 3:144,279,096...144,323,572
Ensembl chr 3:144,279,096...144,323,572
JBrowse link
G Ngf nerve growth factor increases expression EXP 2,3-pentanedione results in increased expression of NGF mRNA CTD PMID:25710175 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452
JBrowse link
G Nkain1 Sodium/potassium transporting ATPase interacting 1 increases expression EXP 2,3-pentanedione results in increased expression of NKAIN1 mRNA CTD PMID:25710175 NCBI chr 5:142,747,702...142,792,665
Ensembl chr 5:142,747,505...142,791,863
JBrowse link
G Nog noggin increases expression EXP 2,3-pentanedione results in increased expression of NOG mRNA CTD PMID:25710175 NCBI chr10:74,128,712...74,130,339
Ensembl chr10:74,128,712...74,130,339
JBrowse link
G Nrg1 neuregulin 1 increases expression EXP 2,3-pentanedione results in increased expression of NRG1 mRNA CTD PMID:25710175 NCBI chr16:59,250,658...60,303,024
Ensembl chr16:59,250,854...60,296,884
JBrowse link
G Papss2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 decreases expression ISO 2,3-pentanedione results in decreased expression of PAPSS2 mRNA CTD PMID:30710127 NCBI chr 1:230,454,314...230,539,332
Ensembl chr 1:230,454,426...230,539,331
JBrowse link
G Pdgfrb platelet derived growth factor receptor beta increases expression EXP 2,3-pentanedione results in increased expression of PDGFRB mRNA CTD PMID:25710175 NCBI chr18:54,500,002...54,538,843
Ensembl chr18:54,499,964...54,538,843
JBrowse link
G Plat plasminogen activator, tissue type increases expression EXP 2,3-pentanedione results in increased expression of PLAT mRNA CTD PMID:25710175 NCBI chr16:69,240,582...69,265,177
Ensembl chr16:69,240,585...69,268,223
JBrowse link
G Plau plasminogen activator, urokinase increases expression EXP 2,3-pentanedione results in increased expression of PLAU mRNA CTD PMID:25710175 NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775
JBrowse link
G Plaur plasminogen activator, urokinase receptor increases expression EXP 2,3-pentanedione results in increased expression of PLAUR mRNA CTD PMID:25710175 NCBI chr 1:80,053,441...80,068,384
Ensembl chr 1:80,050,324...80,068,595
JBrowse link
G Plod2 procollagen lysine, 2-oxoglutarate 5-dioxygenase 2 increases expression EXP 2,3-pentanedione results in increased expression of PLOD2 mRNA CTD PMID:25710175 NCBI chr 8:93,084,548...93,167,255
Ensembl chr 8:93,084,513...93,167,255
JBrowse link
G Pon1 paraoxonase 1 decreases expression EXP 2,3-pentanedione results in decreased expression of PON1 mRNA CTD PMID:25710175 NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha decreases expression EXP 2,3-pentanedione results in decreased expression of PPARA mRNA CTD PMID:25710175 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Prom1 prominin 1 decreases expression ISO 2,3-pentanedione results in decreased expression of PROM1 mRNA CTD PMID:30710127 NCBI chr14:66,989,545...67,094,534
Ensembl chr14:66,990,160...67,094,527
JBrowse link
G Prss22 serine protease 22 increases expression EXP 2,3-pentanedione results in increased expression of PRSS22 mRNA CTD PMID:25710175 NCBI chr10:13,029,153...13,033,863
Ensembl chr10:13,029,153...13,033,863
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression ISO 2,3-pentanedione results in decreased expression of PTGS2 mRNA CTD PMID:30710127 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Pthlh parathyroid hormone-like hormone decreases expression ISO 2,3-pentanedione results in decreased expression of PTHLH mRNA CTD PMID:30710127 NCBI chr 4:180,188,792...180,199,847
Ensembl chr 4:180,188,792...180,199,847
JBrowse link
G Rasgrp1 RAS guanyl releasing protein 1 decreases expression EXP 2,3-pentanedione results in decreased expression of RASGRP1 mRNA CTD PMID:25710175 NCBI chr 3:104,168,549...104,230,107
Ensembl chr 3:104,170,013...104,230,056
JBrowse link
G S100a1 S100 calcium binding protein A1 decreases expression EXP 2,3-pentanedione results in decreased expression of S100A1 mRNA CTD PMID:25710175 NCBI chr 2:175,993,922...175,998,765
Ensembl chr 2:175,993,922...175,999,544
JBrowse link
G S1pr1 sphingosine-1-phosphate receptor 1 decreases expression EXP 2,3-pentanedione results in decreased expression of S1PR1 mRNA CTD PMID:25710175 NCBI chr 2:203,624,752...203,629,110
Ensembl chr 2:203,621,587...203,629,681
JBrowse link
G Sbp spermine binding protein decreases expression EXP 2,3-pentanedione results in decreased expression of SBP mRNA CTD PMID:25710175 NCBI chr10:12,946,036...12,968,439
Ensembl chr10:12,946,036...12,968,439
JBrowse link
G Scgb1a1 secretoglobin family 1A member 1 increases expression ISO 2,3-pentanedione results in increased expression of SCGB1A1 mRNA CTD PMID:30710127 NCBI chr 1:205,977,060...205,980,610
Ensembl chr 1:205,977,060...205,980,610
JBrowse link
G Sec14l3 SEC14-like lipid binding 3 decreases expression EXP 2,3-pentanedione results in decreased expression of SEC14L3 mRNA CTD PMID:25710175 NCBI chr14:78,944,568...78,955,608 JBrowse link
G Serpinb5 serpin family B member 5 decreases expression EXP 2,3-pentanedione results in decreased expression of SERPINB5 mRNA CTD PMID:25710175 NCBI chr13:22,985,557...23,005,756
Ensembl chr13:22,985,557...23,005,756
JBrowse link
G Serpine1 serpin family E member 1 increases expression EXP 2,3-pentanedione results in increased expression of SERPINE1 mRNA CTD PMID:25710175 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
JBrowse link
G Serpinf1 serpin family F member 1 increases expression EXP 2,3-pentanedione results in increased expression of SERPINF1 mRNA CTD PMID:25710175 NCBI chr10:60,250,198...60,262,593
Ensembl chr10:60,249,708...60,262,646
JBrowse link
G Serping1 serpin family G member 1 increases expression EXP 2,3-pentanedione results in increased expression of SERPING1 mRNA CTD PMID:25710175 NCBI chr 3:69,842,726...69,852,583
Ensembl chr 3:69,842,739...69,852,034
JBrowse link
G Serpinh1 serpin family H member 1 increases expression EXP 2,3-pentanedione results in increased expression of SERPINH1 mRNA CTD PMID:25710175 NCBI chr 1:153,643,500...153,650,853
Ensembl chr 1:153,643,510...153,650,801
JBrowse link
G Slc15a1 solute carrier family 15 member 1 increases expression EXP 2,3-pentanedione results in increased expression of SLC15A1 mRNA CTD PMID:25710175 NCBI chr15:98,537,641...98,582,544
Ensembl chr15:98,537,641...98,582,545
JBrowse link
G Slc15a2 solute carrier family 15 member 2 decreases expression EXP 2,3-pentanedione results in decreased expression of SLC15A2 mRNA CTD PMID:25710175 NCBI chr11:64,014,182...64,043,228
Ensembl chr11:64,014,182...64,043,225
JBrowse link
G Slc23a1 solute carrier family 23 member 1 decreases expression EXP 2,3-pentanedione results in decreased expression of SLC23A1 mRNA CTD PMID:25710175 NCBI chr18:27,214,940...27,230,564
Ensembl chr18:27,216,281...27,230,697
JBrowse link
G Sorcs2 sortilin-related VPS10 domain containing receptor 2 decreases expression ISO 2,3-pentanedione results in decreased expression of SORCS2 mRNA CTD PMID:30710127 NCBI chr14:74,371,089...74,735,943
Ensembl chr14:74,371,415...74,735,943
JBrowse link
G Sorl1 sortilin related receptor 1 decreases expression EXP 2,3-pentanedione results in decreased expression of SORL1 mRNA CTD PMID:25710175 NCBI chr 8:42,341,704...42,504,435
Ensembl chr 8:42,341,704...42,504,513
JBrowse link
G Spag17 sperm associated antigen 17 decreases expression ISO 2,3-pentanedione results in decreased expression of SPAG17 mRNA CTD PMID:30710127 NCBI chr 2:187,264,004...187,511,061
Ensembl chr 2:187,264,009...187,510,501
JBrowse link
G Spon1 spondin 1 increases expression EXP 2,3-pentanedione results in increased expression of SPON1 mRNA CTD PMID:25710175 NCBI chr 1:167,929,049...168,228,239
Ensembl chr 1:167,928,972...168,228,226
JBrowse link
G Spp1 secreted phosphoprotein 1 increases expression EXP 2,3-pentanedione results in increased expression of SPP1 mRNA CTD PMID:25710175 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162
JBrowse link
G Spr sepiapterin reductase decreases expression EXP 2,3-pentanedione results in decreased expression of SPR mRNA CTD PMID:25710175 NCBI chr 4:117,671,948...117,676,292
Ensembl chr 4:117,671,949...117,675,678
JBrowse link
G Stra6 signaling receptor and transporter of retinol STRA6 decreases expression EXP 2,3-pentanedione results in decreased expression of STRA6 mRNA CTD PMID:25710175 NCBI chr 8:58,549,743...58,568,861
Ensembl chr 8:58,549,736...58,568,860
JBrowse link
G Tekt1 tektin 1 decreases expression ISO 2,3-pentanedione results in decreased expression of TEKT1 mRNA CTD PMID:30710127 NCBI chr10:56,952,164...56,980,572
Ensembl chr10:56,952,167...56,980,572
JBrowse link
G Tgfb2 transforming growth factor, beta 2 increases expression EXP 2,3-pentanedione results in increased expression of TGFB2 mRNA CTD PMID:25710175 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405
JBrowse link
G Tgfbi transforming growth factor, beta induced increases expression EXP 2,3-pentanedione results in increased expression of TGFBI mRNA CTD PMID:25710175 NCBI chr17:7,955,603...7,984,903
Ensembl chr17:7,955,603...7,985,240
JBrowse link
G Tgm1 transglutaminase 1 increases expression EXP 2,3-pentanedione results in increased expression of TGM1 mRNA CTD PMID:25710175 NCBI chr15:29,191,039...29,206,000
Ensembl chr15:29,191,041...29,204,523
JBrowse link
G Thbs2 thrombospondin 2 increases expression EXP 2,3-pentanedione results in increased expression of THBS2 mRNA CTD PMID:25710175 NCBI chr 1:55,670,394...55,699,789
Ensembl chr 1:55,670,394...55,699,789
JBrowse link
G Thbs4 thrombospondin 4 decreases expression EXP 2,3-pentanedione results in decreased expression of THBS4 mRNA CTD PMID:25710175 NCBI chr 2:23,983,158...24,025,289
Ensembl chr 2:23,983,158...24,026,313
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 increases expression EXP 2,3-pentanedione results in increased expression of TIMP1 mRNA CTD PMID:25710175 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664
JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 increases expression EXP 2,3-pentanedione results in increased expression of TIMP2 mRNA CTD PMID:25710175 NCBI chr10:103,541,199...103,590,611 JBrowse link
G Timp4 TIMP metallopeptidase inhibitor 4 decreases expression EXP 2,3-pentanedione results in decreased expression of TIMP4 mRNA CTD PMID:25710175 NCBI chr 4:148,306,021...148,312,558
Ensembl chr 4:148,304,490...148,312,558
JBrowse link
G Tlr2 toll-like receptor 2 decreases expression EXP 2,3-pentanedione results in decreased expression of TLR2 mRNA CTD PMID:25710175 NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630
JBrowse link
G Tmem178a transmembrane protein 178A increases expression EXP 2,3-pentanedione results in increased expression of TMEM178 mRNA CTD PMID:25710175 NCBI chr 6:14,004,629...14,063,677
Ensembl chr 6:14,004,630...14,063,549
JBrowse link
G Tnc tenascin C increases expression EXP 2,3-pentanedione results in increased expression of TNC mRNA CTD PMID:25710175 NCBI chr 5:77,375,851...77,460,712
Ensembl chr 5:77,375,851...77,460,624
JBrowse link
G Tnfaip6 TNF alpha induced protein 6 increases expression EXP 2,3-pentanedione results in increased expression of TNFAIP6 mRNA CTD PMID:25710175 NCBI chr 3:36,502,250...36,521,652
Ensembl chr 3:36,502,188...36,521,649
JBrowse link
G Tnfrsf12a TNF receptor superfamily member 12A increases expression EXP 2,3-pentanedione results in increased expression of TNFRSF12A mRNA CTD PMID:25710175 NCBI chr10:12,707,077...12,709,071
Ensembl chr10:12,689,890...12,709,045
JBrowse link
G Tnn tenascin N increases expression EXP 2,3-pentanedione results in increased expression of TNN mRNA CTD PMID:25710175 NCBI chr13:72,319,160...72,386,362
Ensembl chr13:72,319,155...72,408,156
JBrowse link
G Ubr2 ubiquitin protein ligase E3 component n-recognin 2 increases expression EXP 2,3-pentanedione results in increased expression of UBR2 mRNA CTD PMID:25710175 NCBI chr 9:13,982,427...14,062,315
Ensembl chr 9:13,982,329...14,062,139
JBrowse link
G Zfp318 zinc finger protein 318 increases expression EXP 2,3-pentanedione results in increased expression of ZFP318 mRNA CTD PMID:25710175 NCBI chr 9:14,562,958...14,601,557
Ensembl chr 9:14,563,313...14,601,409
JBrowse link
G Zfp853 zinc finger protein 853 decreases expression EXP 2,3-pentanedione results in decreased expression of ZFP853 mRNA CTD PMID:25710175 NCBI chr12:11,266,124...11,276,492
Ensembl chr12:11,269,414...11,275,731
JBrowse link
phenacyl bromide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh2 aldehyde dehydrogenase 2 family member multiple interactions ISO phenacyl bromide inhibits the reaction [4-dimethylaminocinnamaldehyde binds to ALDH2 protein] CTD PMID:10609638 NCBI chr12:34,949,549...34,982,527 JBrowse link
raspberry ketone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor multiple interactions ISO raspberry ketone binds to and results in decreased activity of AR protein CTD PMID:20226658 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression
multiple interactions
ISO raspberry ketone results in increased expression of DDIT3 mRNA
Acetylcysteine inhibits the reaction [raspberry ketone results in increased expression of DDIT3 mRNA]
CTD PMID:26867644 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression
multiple interactions
ISO raspberry ketone results in increased expression of GADD45A mRNA
Acetylcysteine inhibits the reaction [raspberry ketone results in increased expression of GADD45A mRNA]
CTD PMID:26867644 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions
decreases expression
ISO Acetylcysteine inhibits the reaction [raspberry ketone results in decreased expression of GPX1 protein] CTD PMID:26867644 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G LOC686683 similar to olfactory receptor 73 multiple interactions ISO raspberry ketone binds to and results in increased activity of OLFR73 protein CTD PMID:21142015 NCBI chr 3:73,516,522...73,517,463 JBrowse link
rottlerin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase multiple interactions ISO rottlerin inhibits the reaction [[ABL1 protein results in increased phosphorylation of and results in decreased activity of PPARG protein] which results in increased expression of COL1A1 protein] CTD PMID:17030193 NCBI chr 3:14,979,853...15,083,065
Ensembl chr 3:14,979,853...15,083,065
JBrowse link
G Acat1 acetyl-CoA acetyltransferase 1 multiple interactions ISO rottlerin inhibits the reaction [Serotonin results in increased expression of ACAT1 protein] CTD PMID:16157345 NCBI chr 8:53,979,813...54,008,861
Ensembl chr 8:53,979,813...54,008,855
JBrowse link
G Agt angiotensinogen multiple interactions EXP rottlerin inhibits the reaction [AGT protein affects the localization of ELAVL1 protein] CTD PMID:19246637 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
JBrowse link
G Aif1 allograft inflammatory factor 1 multiple interactions ISO rottlerin inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin results in increased expression of AIF1 protein] CTD PMID:30366073 NCBI chr20:3,646,784...3,652,670
Ensembl chr20:3,646,777...3,652,668
JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases phosphorylation
multiple interactions
ISO rottlerin results in decreased phosphorylation of AKT1 protein
rottlerin inhibits the reaction [NTS protein results in increased phosphorylation of and results in increased activity of AKT1 protein]
CTD PMID:15177934 PMID:19393235 PMID:22902833 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G App amyloid beta precursor protein multiple interactions EXP rottlerin inhibits the reaction [PRKCD protein promotes the reaction [Lead results in increased localization of APP protein]] CTD PMID:20488202 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Atg7 autophagy related 7 multiple interactions
increases expression
ISO 3-methyladenine inhibits the reaction [rottlerin results in increased expression of ATG7 protein] CTD PMID:22902833 NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593
JBrowse link
G Bad BCL2-associated agonist of cell death multiple interactions ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [rottlerin inhibits the reaction [trimethyltin results in decreased expression of BAD protein modified form]]; rottlerin inhibits the reaction [trimethyltin results in decreased expression of BAD protein modified form] CTD PMID:25895139 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
JBrowse link
G Bak1 BCL2-antagonist/killer 1 multiple interactions ISO rottlerin inhibits the reaction [Doxorubicin results in increased activity of BAK1 protein] CTD PMID:15917298 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
increases expression
ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [rottlerin inhibits the reaction [trimethyltin results in increased expression of BAX protein]]; rottlerin inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin results in increased expression of BAX protein]; rottlerin inhibits the reaction [Cisplatin affects the localization of BAX protein]; rottlerin inhibits the reaction [trimethyltin results in increased expression of BAX protein]
rottlerin results in increased expression of BAX protein
CTD PMID:21633170 PMID:22902833 PMID:25895139 PMID:30366073 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
multiple interactions
ISO rottlerin results in decreased expression of BCL2 protein
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [rottlerin inhibits the reaction [trimethyltin results in decreased expression of BCL2 protein]]; rottlerin inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin results in decreased expression of BCL2 protein]; rottlerin inhibits the reaction [Cocaine results in decreased expression of BCL2 protein]; rottlerin inhibits the reaction [trimethyltin results in decreased expression of BCL2 protein]
CTD PMID:22902833 PMID:25895139 PMID:30366073 PMID:30393195 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression
multiple interactions
ISO rottlerin results in decreased expression of BCL2L1 protein
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [rottlerin inhibits the reaction [trimethyltin results in decreased expression of BCL2L1 protein]]; rottlerin inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin results in decreased expression of BCL2L1 protein]; rottlerin inhibits the reaction [Cocaine results in decreased expression of BCL2L1 protein]; rottlerin inhibits the reaction [trimethyltin results in decreased expression of BCL2L1 protein]
CTD PMID:22902833 PMID:25895139 PMID:30366073 PMID:30393195 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Becn1 beclin 1 multiple interactions
increases expression
ISO 3-methyladenine inhibits the reaction [rottlerin results in increased expression of BECN1 protein] CTD PMID:22902833 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 multiple interactions ISO rottlerin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BIRC3 mRNA] CTD PMID:14527959 NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802
JBrowse link
G Casp3 caspase 3 decreases activity
multiple interactions
increases cleavage
increases activity
EXP
ISO
rottlerin results in decreased activity of CASP3 protein
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [rottlerin inhibits the reaction [trimethyltin results in increased expression of CASP3 protein modified form]]; rottlerin inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin results in increased cleavage of CASP3 protein]; rottlerin inhibits the reaction [Cocaine results in increased cleavage of CASP3 protein]; rottlerin inhibits the reaction [trimethyltin results in increased expression of CASP3 protein modified form]
rottlerin results in increased cleavage of CASP3 protein
rottlerin inhibits the reaction [NSC606985 results in increased activity of CASP3 protein]; rottlerin inhibits the reaction [Ursodeoxycholic Acid results in increased cleavage of CASP3 protein]
rottlerin results in increased activity of CASP3 protein
rottlerin inhibits the reaction [2-methylcyclopentadienyl manganese tricarbonyl results in increased activity of CASP3 protein]; rottlerin inhibits the reaction [Dieldrin results in increased activity of CASP3 protein]; rottlerin inhibits the reaction [naringin inhibits the reaction [[Oxygen deficiency co-treated with Oxygen] results in increased cleavage of and results in increased activity of CASP3 protein]]
CTD PMID:11880503 PMID:12831855 PMID:19662097 PMID:21362627 PMID:22410117 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp6 caspase 6 multiple interactions ISO rottlerin inhibits the reaction [Ursodeoxycholic Acid results in increased cleavage of CASP6 protein] CTD PMID:21362627 NCBI chr 2:218,466,063...218,478,503
Ensembl chr 2:218,466,076...218,478,502
JBrowse link
G Casp9 caspase 9 multiple interactions
increases cleavage
ISO rottlerin inhibits the reaction [Asbestos, Crocidolite results in increased cleavage of CASP9 protein]; rottlerin inhibits the reaction [Phorbol 12,13-Dibutyrate results in increased cleavage of CASP9 protein]
rottlerin results in increased cleavage of CASP9 protein
CTD PMID:12626342 PMID:22902833 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Ccnd1 cyclin D1 multiple interactions ISO [sorafenib co-treated with rottlerin] results in decreased expression of CCND1 protein CTD PMID:16959960 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccnd3 cyclin D3 multiple interactions ISO [sorafenib co-treated with rottlerin] results in decreased expression of CCND3 protein CTD PMID:16959960 NCBI chr 9:13,394,161...13,400,341
Ensembl chr 9:13,394,169...13,489,371
JBrowse link
G Cd38 CD38 molecule multiple interactions ISO rottlerin inhibits the reaction [Tretinoin results in increased expression of CD38 mRNA]; rottlerin inhibits the reaction [Tretinoin results in increased expression of CD38 protein] CTD PMID:21393419 NCBI chr14:67,172,062...67,212,328
Ensembl chr14:67,172,063...67,211,986
JBrowse link
G Cdk4 cyclin-dependent kinase 4 multiple interactions ISO [sorafenib co-treated with rottlerin] results in decreased expression of CDK4 protein CTD PMID:16959960 NCBI chr 7:62,885,647...62,889,562
Ensembl chr 7:62,883,105...62,942,403
JBrowse link
G Cdk6 cyclin-dependent kinase 6 multiple interactions ISO [sorafenib co-treated with rottlerin] results in decreased expression of CDK6 protein CTD PMID:16959960 NCBI chr 4:30,637,650...30,829,688
Ensembl chr 4:30,646,460...30,829,634
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions ISO rottlerin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CDKN1A protein] CTD PMID:15976015 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha multiple interactions ISO rottlerin inhibits the reaction [NSC606985 results in decreased expression of CEBPA protein]; rottlerin inhibits the reaction [NSC606985 results in increased ubiquitination of CEBPA protein] CTD PMID:19662097 NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412
JBrowse link
G Cldn1 claudin 1 affects localization ISO rottlerin affects the localization of CLDN1 protein CTD PMID:19297429 NCBI chr11:74,421,569...74,436,728
Ensembl chr11:74,421,569...74,436,724
JBrowse link
G Cldn4 claudin 4 multiple interactions ISO rottlerin results in increased expression of and affects the localization of CLDN4 protein CTD PMID:19297429 NCBI chr12:21,751,638...21,753,436
Ensembl chr12:21,751,331...21,753,436
JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions ISO rottlerin inhibits the reaction [[ABL1 protein results in increased phosphorylation of and results in decreased activity of PPARG protein] which results in increased expression of COL1A1 protein]; rottlerin inhibits the reaction [Acetaldehyde results in increased expression of COL1A1 mRNA]; rottlerin inhibits the reaction [Acetaldehyde results in increased expression of COL1A1 protein] CTD PMID:17030193 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 decreases activity ISO rottlerin results in decreased activity of CYP19A1 protein CTD PMID:15955695 NCBI chr 8:54,553,165...54,580,758
Ensembl chr 8:54,553,165...54,580,758
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions
increases expression
ISO
EXP
rottlerin inhibits the reaction [Curcumin results in increased expression of DDIT3 mRNA]
rottlerin inhibits the reaction [Cadmium results in increased expression of DDIT3 protein]
rottlerin results in increased expression of DDIT3 protein
CTD PMID:17171638 PMID:22410117 PMID:27658547 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Eef2 eukaryotic translation elongation factor 2 decreases phosphorylation EXP rottlerin results in decreased phosphorylation of EEF2 protein CTD PMID:12720544 NCBI chr 7:8,533,248...8,538,518
Ensembl chr 7:8,533,116...8,559,183
JBrowse link
G Egfr epidermal growth factor receptor multiple interactions ISO rottlerin inhibits the reaction [irinotecan metabolite results in increased phosphorylation of EGFR protein]; rottlerin inhibits the reaction [irinotecan results in increased phosphorylation of EGFR protein]; rottlerin inhibits the reaction [NTS protein results in increased phosphorylation of and results in increased activity of EGFR protein] CTD PMID:15177934 PMID:15723263 NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Eif4e eukaryotic translation initiation factor 4E multiple interactions ISO rottlerin promotes the reaction [EIF4E protein binds to EIF4EBP1 protein] CTD PMID:19771169 NCBI chr 2:227,066,519...227,099,261
Ensembl chr 2:227,066,673...227,098,683
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 multiple interactions ISO
EXP
rottlerin inhibits the reaction [MTOR protein results in increased phosphorylation of EIF4EBP1 protein]; rottlerin promotes the reaction [EIF4E protein binds to EIF4EBP1 protein]
rottlerin inhibits the reaction [Phenylephrine results in increased phosphorylation of EIF4EBP1 protein]
CTD PMID:12720544 PMID:19771169 NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984
JBrowse link
G Elavl1 ELAV like RNA binding protein 1 multiple interactions EXP rottlerin inhibits the reaction [AGT protein affects the localization of ELAVL1 protein] CTD PMID:19246637 NCBI chr12:2,640,936...2,684,787
Ensembl chr12:2,645,061...2,684,784
JBrowse link
G Fgf1 fibroblast growth factor 1 multiple interactions ISO rottlerin inhibits the reaction [PRKCD protein results in increased phosphorylation of FGF1 protein] CTD PMID:15574884 NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,686,581...30,772,357
JBrowse link
G Fgf2 fibroblast growth factor 2 multiple interactions ISO rottlerin inhibits the reaction [FGF2 protein results in increased activity of RUNX2 protein]; rottlerin inhibits the reaction [FGF2 protein results in increased expression of RUNX2 mRNA] CTD PMID:12403780 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221
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G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO rottlerin inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of FOS protein] CTD PMID:20599481 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
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G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions ISO
EXP
rottlerin inhibits the reaction [[3-methylquercetin results in increased activity of NFE2L2 protein] which results in increased expression of GCLC protein]; rottlerin inhibits the reaction [Plant Extracts results in increased expression of GCLC protein]
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [rottlerin promotes the reaction [trimethyltin results in increased expression of GCLC mRNA]]; rottlerin inhibits the reaction [Exenatide results in increased expression of GCLC protein]; rottlerin promotes the reaction [Cocaine results in increased expression of GCLC mRNA]; rottlerin promotes the reaction [trimethyltin results in increased expression of GCLC mRNA]
rottlerin inhibits the reaction [naringin results in increased expression of GCLC protein]
CTD PMID:24211276 PMID:25773745 PMID:25895139 PMID:27939242 PMID:30393195 More... NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
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G Gclm glutamate cysteine ligase, modifier subunit multiple interactions ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [rottlerin promotes the reaction [trimethyltin results in increased expression of GCLM mRNA]]; rottlerin promotes the reaction [Cocaine results in increased expression of GCLM mRNA]; rottlerin promotes the reaction [trimethyltin results in increased expression of GCLM mRNA] CTD PMID:25895139 PMID:30393195 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
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G Gdf15 growth differentiation factor 15 multiple interactions
affects response to substance
increases expression
ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [rottlerin results in increased expression of GDF15 protein]; SB 203580 inhibits the reaction [rottlerin results in increased expression of GDF15 protein]
GDF15 affects the susceptibility to rottlerin
rottlerin results in increased expression of GDF15 mRNA; rottlerin results in increased expression of GDF15 protein
CTD PMID:22410117 NCBI chr16:18,805,312...18,807,893
Ensembl chr16:18,805,239...18,808,055
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G Gpt glutamic--pyruvic transaminase multiple interactions EXP
ISO
rottlerin inhibits the reaction [Acrolein results in increased secretion of GPT protein]; rottlerin inhibits the reaction [allyl alcohol results in increased secretion of GPT protein]
rottlerin inhibits the reaction [Cocaine results in increased activity of GPT protein]
CTD PMID:12755590 PMID:30393195 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
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G Grp gastrin releasing peptide multiple interactions ISO rottlerin promotes the reaction [GRP protein modified form results in increased chemical synthesis of Inositol Phosphates] CTD PMID:18313772 NCBI chr18:59,388,679...59,402,061
Ensembl chr18:59,388,274...59,402,061
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G Gsk3a glycogen synthase kinase 3 alpha decreases expression
multiple interactions
EXP rottlerin results in decreased expression of GSK3A protein
[Cadmium co-treated with rottlerin] results in decreased expression of GSK3A protein
CTD PMID:27658547 NCBI chr 1:80,815,843...80,825,732
Ensembl chr 1:80,815,850...80,825,802
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G Gsk3b glycogen synthase kinase 3 beta multiple interactions
decreases expression
EXP [Cadmium co-treated with rottlerin] results in decreased expression of GSK3B protein; rottlerin inhibits the reaction [Cadmium results in increased phosphorylation of GSK3B protein]
rottlerin results in decreased expression of GSK3B protein
CTD PMID:27658547 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
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G Hamp hepcidin antimicrobial peptide decreases expression ISO rottlerin results in decreased expression of HAMP mRNA CTD PMID:25633564 NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891
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G Hmox1 heme oxygenase 1 multiple interactions ISO
EXP
rottlerin inhibits the reaction [2-butenal results in increased expression of HMOX1 mRNA]; rottlerin inhibits the reaction [2-butenal results in increased expression of HMOX1 protein]; rottlerin inhibits the reaction [[3-methylquercetin results in increased activity of NFE2L2 protein] which results in increased expression of HMOX1 protein]; rottlerin inhibits the reaction [Acrolein results in increased expression of HMOX1 mRNA]; rottlerin inhibits the reaction [Curcumin r