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ONTOLOGY REPORT - ANNOTATIONS


Term:fucoxanthin
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Accession:CHEBI:5186 term browser browse the term
Definition:An epoxycarotenol that is found in brown seaweed and which exhibits anti-cancer, anti-diabetic, anti-oxidative and neuroprotective properties.
Synonyms:exact_synonym: (3S,5R,6S,3'S,5'R,6'R)-3,5'-dihydroxy-8-oxo-6',7'-didehydro-5,6-epoxy-5,6,7,8,5',6'-hexahydro-beta,beta-caroten-3'-yl acetate
 related_synonym: (3'S,5'R,6'R)-3'-acetoxy-5,6-epoxy-3,5'-dihydroxy-6',7'-didehydro-5,6,7,8,5',6'-hexahydro-beta,beta-caroten-8-one;   (3S,3'S,5R,5'R,6S,6'R)-3'-(acetyloxy)-6',7'-didehydro-5,6-epoxy-5,5',6,6',7,8-hexahydro-3,5'-dihydroxy-8-oxo-beta,beta-carotene;   Formula=C42H58O6;   InChI=1S/C42H58O6/c1-29(18-14-19-31(3)22-23-37-38(6,7)26-35(47-33(5)43)27-40(37,10)46)16-12-13-17-30(2)20-15-21-32(4)36(45)28-42-39(8,9)24-34(44)25-41(42,11)48-42/h12-22,34-35,44,46H,24-28H2,1-11H3/b13-12+,18-14+,20-15+,29-16+,30-17+,31-19+,32-21+/t23-,34-,35-,40+,41+,42-/m0/s1;   InChIKey=SJWWTRQNNRNTPU-XJUZQKKNSA-N;   SMILES=[H]C(=C=C1C(C)(C)C[C@@H](C[C@@]1(C)O)OC(C)=O)C(\\C)=C\\C=C\\C(C)=C\\C=C\\C=C(C)\\C=C\\C=C(/C)C(=O)C[C@@]12O[C@]1(C)C[C@@H](O)CC2(C)C
 alt_id: CHEBI:67925
 xref: Beilstein:6580822;   CAS:3351-86-8;   KEGG:C08596;   KNApSAcK:C00003773;   LIPID_MAPS_instance:LMPR01070300
 xref_mesh: MESH:C025164
 xref: PMID:16786166;   PMID:17436581;   PMID:18230364;   PMID:19264501;   PMID:19797858;   PMID:27283644;   PMID:27399729;   PMID:27430384;   PMID:27455130;   PMID:27590588;   PMID:27785684;   PMID:27914891;   PMID:27960297;   PMID:28070550;   PMID:28212270;   PMID:28373414;   PMID:28382818;   PMID:28387741;   PMID:28389351;   PMID:28429775;   PMID:28469544;   PMID:28478680;   PMID:28642129;   PMID:28850007;   PMID:28865626;   PMID:28928905;   Reaxys:6580822


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fucoxanthin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acox1 acyl-CoA oxidase 1 JBrowse link 10 104,724,534 104,748,003 RGD:6480464
G Akt1 AKT serine/threonine kinase 1 JBrowse link 6 137,218,398 137,239,970 RGD:6480464
G Bcl2l1 Bcl2-like 1 JBrowse link 3 148,259,594 148,314,191 RGD:6480464
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:6480464
G Casp7 caspase 7 JBrowse link 1 277,190,557 277,242,779 RGD:6480464
G Cat catalase JBrowse link 3 93,379,872 93,412,058 RGD:6480464
G Drd3 dopamine receptor D3 JBrowse link 11 61,819,102 61,883,223 RGD:6480464
G Drd4 dopamine receptor D4 JBrowse link 1 214,278,296 214,282,818 RGD:6480464
G Flg filaggrin JBrowse link 2 193,565,401 193,574,297 RGD:6480464
G Gja1 gap junction protein, alpha 1 JBrowse link 20 37,876,650 37,889,097 RGD:6480464
G Gjb1 gap junction protein, beta 1 JBrowse link X 71,272,030 71,279,973 RGD:6480464
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase JBrowse link 2 27,480,224 27,500,654 RGD:6480464
G Hmox1 heme oxygenase 1 JBrowse link 19 14,508,634 14,515,455 RGD:6480464
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:6480464
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:6480464
G Maoa monoamine oxidase A JBrowse link X 6,554,698 6,620,722 RGD:6480464
G Maob monoamine oxidase B JBrowse link X 6,430,694 6,533,520 RGD:6480464
G Mapk1 mitogen activated protein kinase 1 JBrowse link 11 88,203,863 88,273,301 RGD:6480464
G Mapk3 mitogen activated protein kinase 3 JBrowse link 1 198,192,773 198,198,975 RGD:6480464
G Nos2 nitric oxide synthase 2 JBrowse link 10 66,188,290 66,221,621 RGD:6480464
G Ppara peroxisome proliferator activated receptor alpha JBrowse link 7 126,618,872 126,687,282 RGD:6480464
G Pparg peroxisome proliferator-activated receptor gamma JBrowse link 4 147,274,055 147,399,383 RGD:6480464
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:6480464
G Retn resistin JBrowse link 12 2,201,909 2,203,649 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19790
    role 19738
      biological role 19737
        inhibitor 18180
          apoptosis inhibitor 6728
            fucoxanthin 25
Path 2
Term Annotations click to browse term
  CHEBI ontology 19790
    subatomic particle 19788
      composite particle 19788
        hadron 19788
          baryon 19788
            nucleon 19788
              atomic nucleus 19788
                atom 19788
                  main group element atom 19674
                    main group molecular entity 19674
                      s-block molecular entity 19416
                        hydrogen molecular entity 19407
                          hydrides 18389
                            organic hydride 17747
                              organic fundamental parent 17747
                                hydrocarbon 17255
                                  terpene 9508
                                    tetraterpene 411
                                      carotene 411
                                        carotenoid 411
                                          xanthophyll 154
                                            epoxycarotenoid 28
                                              epoxycarotenol 28
                                                fucoxanthin 25
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.