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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:fucoidan
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Accession:CHEBI:5181 term browser browse the term
Definition:A type of fucose-rich sulfated polysaccharide found in various species of brown algae, seaweed and sea-cucumbers.
Synonyms:related_synonym: Fucan sulfate;   Fucoidin;   Laminaria japonica extract;   Sulfated fucans
 xref: CAS:9072-19-9;   KEGG:C08253
 xref_mesh: MESH:C007789
 xref: MetaCyc:Fucoidans;   PMID:25141794;   PMID:25407449;   PMID:25439948;   PMID:25445688;   PMID:25451746;   PMID:25453283;   PMID:25546518;   PMID:25572360;   PMID:25605994;   PMID:25606812;   PMID:25672488;   PMID:25690093;   PMID:25692870;   PMID:25693733;   PMID:25706632;   PMID:25766803;   Reaxys:8189694;   Wikipedia:Fucoidan


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fucoidan term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Birc2 baculoviral IAP repeat-containing 2 decreases expression ISO fucoidan results in decreased expression of BIRC2 protein CTD PMID:16201850 NCBI chr 8:6,014,014...6,036,668
Ensembl chr 8:6,013,207...6,034,142
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases expression ISO fucoidan results in decreased expression of BIRC5 protein CTD PMID:16201850 NCBI chr10:106,856,097...106,864,419
Ensembl chr10:106,856,097...106,864,413
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 decreases expression ISO fucoidan results in decreased expression of CCL5 protein CTD PMID:16201850 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315
JBrowse link
G Ccnd2 cyclin D2 decreases expression ISO fucoidan results in decreased expression of CCND2 protein CTD PMID:16201850 NCBI chr 4:159,674,885...159,697,207
Ensembl chr 4:159,674,885...159,697,207
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO fucoidan results in increased expression of CDKN1A CTD PMID:24333868 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Gast gastrin multiple interactions EXP fucoidan analog inhibits the reaction [Cisplatin results in decreased expression of GAST protein] CTD PMID:23022014 NCBI chr10:88,245,532...88,248,485
Ensembl chr10:88,245,532...88,248,484
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions EXP fucoidan inhibits the reaction [Aspirin results in increased expression of GPT protein] CTD PMID:19788892 NCBI chr 7:117,759,083...117,761,932
Ensembl chr 7:117,759,083...117,761,931
JBrowse link
G Ifng interferon gamma multiple interactions EXP fucoidan promotes the reaction [Aspirin results in increased expression of IFNG protein] CTD PMID:19788892 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Il10 interleukin 10 multiple interactions EXP fucoidan promotes the reaction [Aspirin results in increased expression of IL10 protein] CTD PMID:19788892 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO fucoidan inhibits the reaction [IL1B protein results in increased secretion of MMP3 protein] CTD PMID:16364234 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il6 interleukin 6 multiple interactions EXP fucoidan inhibits the reaction [Aspirin results in increased expression of IL6 protein] CTD PMID:19788892 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Jund JunD proto-oncogene, AP-1 transcription factor subunit decreases activity ISO fucoidan results in decreased activity of JUND protein CTD PMID:16201850 NCBI chr16:20,485,028...20,486,707
Ensembl chr16:20,485,029...20,486,707
JBrowse link
G Mmp2 matrix metallopeptidase 2 decreases secretion ISO fucoidan results in decreased secretion of MMP2 protein CTD PMID:16364234 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Mmp3 matrix metallopeptidase 3 multiple interactions ISO fucoidan inhibits the reaction [IL1B protein results in increased secretion of MMP3 protein] CTD PMID:16364234 NCBI chr 8:5,676,608...5,698,579
Ensembl chr 8:5,676,665...5,698,579
JBrowse link
G Mmp9 matrix metallopeptidase 9 decreases expression
multiple interactions
ISO fucoidan results in decreased expression of MMP9
wortmannin inhibits the reaction [fucoidan results in decreased expression of MMP9]
CTD PMID:24333868 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mpo myeloperoxidase multiple interactions EXP
ISO
fucoidan inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:15138204, PMID:18209962 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases expression ISO fucoidan results in decreased expression of MYC protein CTD PMID:16201850 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 decreases activity ISO fucoidan results in decreased activity of NFKB1 protein CTD PMID:16201850 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO fucoidan inhibits the reaction [Nanotubes, Carbon inhibits the reaction [endotoxin, Escherichia coli results in increased expression of PTGS2 protein]] CTD PMID:17709331 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Rb1 RB transcriptional corepressor 1 decreases expression ISO fucoidan results in decreased expression of RB1 protein CTD PMID:16201850 NCBI chr15:55,081,582...55,209,060
Ensembl chr15:55,083,140...55,209,342
JBrowse link
G Rel REL proto-oncogene, NF-kB subunit decreases activity ISO fucoidan results in decreased activity of REL protein CTD PMID:16201850 NCBI chr14:108,490,794...108,517,582
Ensembl chr14:108,491,069...108,509,892
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit decreases activity ISO fucoidan results in decreased activity of RELA protein CTD PMID:16201850 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 decreases secretion ISO fucoidan results in decreased secretion of TIMP1 protein CTD PMID:16364234 NCBI chr  X:1,364,771...1,369,451
Ensembl chr  X:1,364,786...1,369,384
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19770
    role 19718
      chemical role 19247
        antioxidant 14202
          fucoidan 23
Path 2
Term Annotations click to browse term
  CHEBI ontology 19770
    subatomic particle 19768
      composite particle 19768
        hadron 19768
          baryon 19768
            nucleon 19768
              atomic nucleus 19768
                atom 19768
                  main group element atom 19655
                    p-block element atom 19655
                      chalcogen 19359
                        oxygen atom 19320
                          oxygen molecular entity 19320
                            hydroxides 19064
                              oxoacid 18185
                                chalcogen oxoacid 11464
                                  sulfur oxoacid 11063
                                    sulfuric acid 8006
                                      sulfuric acid derivative 8006
                                        sulfates 8003
                                          organic sulfate 1932
                                            carbohydrate sulfate 1408
                                              polysaccharide sulfate 1300
                                                fucoidan 23
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