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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:fucoidan
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Accession:CHEBI:5181 term browser browse the term
Definition:A type of fucose-rich sulfated polysaccharide found in various species of brown algae, seaweed and sea-cucumbers.
Synonyms:related_synonym: Fucan sulfate;   Fucoidin;   Laminaria japonica extract;   Sulfated fucans
 xref: CAS:9072-19-9;   KEGG:C08253
 xref_mesh: MESH:C007789
 xref: MetaCyc:Fucoidans;   PMID:25141794;   PMID:25407449;   PMID:25439948;   PMID:25445688;   PMID:25451746;   PMID:25453283;   PMID:25546518;   PMID:25572360;   PMID:25605994;   PMID:25606812;   PMID:25672488;   PMID:25690093;   PMID:25692870;   PMID:25693733;   PMID:25706632;   PMID:25766803;   Reaxys:8189694;   Wikipedia:Fucoidan


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fucoidan term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Birc2 baculoviral IAP repeat-containing 2 decreases expression ISO fucoidan results in decreased expression of BIRC2 protein CTD PMID:16201850 NCBI chr 8:4,968,856...4,989,325
Ensembl chr 8:4,968,842...4,988,732 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases expression ISO fucoidan results in decreased expression of BIRC5 protein CTD PMID:16201850 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 decreases expression ISO fucoidan results in decreased expression of CCL5 protein CTD PMID:16201850 NCBI chr10:68,322,826...68,327,365
Ensembl chr10:68,322,829...68,327,377 		JBrowse link
G Ccnd2 cyclin D2 decreases expression ISO fucoidan results in decreased expression of CCND2 protein CTD PMID:16201850 NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO fucoidan results in increased expression of CDKN1A CTD PMID:24333868 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Gast gastrin multiple interactions EXP fucoidan analog inhibits the reaction [Cisplatin results in decreased expression of GAST protein] CTD PMID:23022014 NCBI chr10:85,264,832...85,269,393
Ensembl chr10:85,264,832...85,267,496 		JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions EXP fucoidan inhibits the reaction [Aspirin results in increased expression of GPT protein] CTD PMID:19788892 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494 		JBrowse link
G Ifng interferon gamma multiple interactions EXP fucoidan promotes the reaction [Aspirin results in increased expression of IFNG protein] CTD PMID:19788892 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Il10 interleukin 10 multiple interactions EXP fucoidan promotes the reaction [Aspirin results in increased expression of IL10 protein] CTD PMID:19788892 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO fucoidan inhibits the reaction [IL1B protein results in increased secretion of MMP3 protein] CTD PMID:16364234 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il6 interleukin 6 multiple interactions EXP fucoidan inhibits the reaction [Aspirin results in increased expression of IL6 protein] CTD PMID:19788892 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Jund JunD proto-oncogene, AP-1 transcription factor subunit decreases activity ISO fucoidan results in decreased activity of JUND protein CTD PMID:16201850 NCBI chr16:18,734,121...18,735,799
Ensembl chr16:18,734,122...18,735,799 		JBrowse link
G Mmp2 matrix metallopeptidase 2 decreases secretion ISO fucoidan results in decreased secretion of MMP2 protein CTD PMID:16364234 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Mmp3 matrix metallopeptidase 3 multiple interactions ISO fucoidan inhibits the reaction [IL1B protein results in increased secretion of MMP3 protein] CTD PMID:16364234 NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961 		JBrowse link
G Mmp9 matrix metallopeptidase 9 decreases expression
multiple interactions		 ISO fucoidan results in decreased expression of MMP9
wortmannin inhibits the reaction [fucoidan results in decreased expression of MMP9]		 CTD PMID:24333868 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Mpo myeloperoxidase multiple interactions EXP
ISO		 fucoidan inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:15138204 PMID:18209962 NCBI chr10:72,594,458...72,608,862
Ensembl chr10:72,594,661...72,604,819 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases expression ISO fucoidan results in decreased expression of MYC protein CTD PMID:16201850 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 decreases activity ISO fucoidan results in decreased activity of NFKB1 protein CTD PMID:16201850 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO fucoidan inhibits the reaction [Nanotubes, Carbon inhibits the reaction [endotoxin, Escherichia coli results in increased expression of PTGS2 protein]] CTD PMID:17709331 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Rb1 RB transcriptional corepressor 1 decreases expression ISO fucoidan results in decreased expression of RB1 protein CTD PMID:16201850 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302 		JBrowse link
G Rel REL proto-oncogene, NF-kB subunit decreases activity ISO fucoidan results in decreased activity of REL protein CTD PMID:16201850 NCBI chr14:97,690,105...97,721,194
Ensembl chr14:97,695,161...97,720,892 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit decreases activity ISO fucoidan results in decreased activity of RELA protein CTD PMID:16201850 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 decreases secretion ISO fucoidan results in decreased secretion of TIMP1 protein CTD PMID:16364234 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19818
    role 19790
      chemical role 19421
        antioxidant 15726
          fucoidan 23
Path 2
Term Annotations click to browse term
  CHEBI ontology 19818
    subatomic particle 19816
      composite particle 19816
        hadron 19816
          baryon 19816
            nucleon 19816
              atomic nucleus 19816
                atom 19816
                  main group element atom 19761
                    p-block element atom 19761
                      chalcogen 19548
                        oxygen atom 19524
                          oxygen molecular entity 19524
                            hydroxides 19312
                              oxoacid 18688
                                chalcogen oxoacid 12916
                                  sulfur oxoacid 12654
                                    sulfuric acid 8222
                                      sulfuric acid derivative 8222
                                        sulfates 8217
                                          organic sulfate 2249
                                            carbohydrate sulfate 1736
                                              polysaccharide sulfate 1635
                                                fucoidan 23
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