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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:friedelin
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Accession:CHEBI:5171 term browser browse the term
Definition:A pentacyclic triterpenoid that is perhydropicene which is substituted by an oxo group at position 3 and by methyl groups at the 4, 4a, 6b, 8a, 11, 11, 12b, and 14a-positions (the 4R,4aS,6aS,6bR,8aR,12aR,12bS,14aS,14bS-enantiomer). It is the major triterpenoid constituent of cork.
Synonyms:exact_synonym: (4R,4aS,6aS,6bR,8aR,12aR,12bS,14aS,14bS)-4,4a,6b,8a,11,11,12b,14a-octamethylicosahydropicen-3(2H)-one
 related_synonym: D:A-friedooleanan-3-one;   Formula=C30H50O;   InChI=1S/C30H50O/c1-20-21(31)9-10-22-27(20,5)12-11-23-28(22,6)16-18-30(8)24-19-25(2,3)13-14-26(24,4)15-17-29(23,30)7/h20,22-24H,9-19H2,1-8H3/t20-,22+,23-,24+,26+,27+,28-,29+,30-/m0/s1;   InChIKey=OFMXGFHWLZPCFL-SVRPQWSVSA-N;   SMILES=[H][C@@]12CCC(=O)[C@H](C)[C@@]1(C)CC[C@@]1([H])[C@@]2(C)CC[C@@]2(C)[C@]3([H])CC(C)(C)CC[C@]3(C)CC[C@]12C;   friedelan-3-one;   friedeline
 xref: CAS:559-74-0;   KEGG:C08626;   KNApSAcK:C00003747
 xref_mesh: MESH:C060796
 xref: MetaCyc:CPD-13047;   PMID:17639555;   PMID:20610397;   PMID:20675291;   PMID:21718291;   Patent:WO2009072916



show annotations for term's descendants           Sort by:
friedelin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 multiple interactions ISO friedelin inhibits the reaction [Ethanol results in increased expression of CASP3 protein] CTD PMID:37939858 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO friedelin inhibits the reaction [Ethanol results in increased expression of PARP1 protein] CTD PMID:37939858 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO friedelin inhibits the reaction [Ethanol results in increased expression of RELA protein] CTD PMID:37939858 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19860
    role 19832
      application 19675
        anti-inflammatory agent 16628
          anti-inflammatory drug 14976
            friedelin 3
              1beta-hydroxyfriedelin 0
              3beta-hydroxyfriedelan-23-oic acid 0
              acetyl aleuritolic acid 0
              friedelin-3,4-lactone 0
              maytenfolone A 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19860
    subatomic particle 19858
      composite particle 19858
        hadron 19858
          baryon 19858
            nucleon 19858
              atomic nucleus 19858
                atom 19858
                  main group element atom 19804
                    p-block element atom 19804
                      carbon group element atom 19745
                        carbon atom 19741
                          organic molecular entity 19741
                            heteroorganic entity 19494
                              organochalcogen compound 19257
                                organooxygen compound 19173
                                  carbonyl compound 18897
                                    ketone 17186
                                      cyclic ketone 15703
                                        alicyclic ketone 1181
                                          cyclic terpene ketone 145
                                            friedelin 3
                                              1beta-hydroxyfriedelin 0
                                              3beta-hydroxyfriedelan-23-oic acid 0
                                              acetyl aleuritolic acid 0
                                              friedelin-3,4-lactone 0
                                              maytenfolone A 0
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