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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:5-carboxyfluorescein
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Accession:CHEBI:51617 term browser browse the term
Definition:A monocarboxylic acid that has formula C21H12O7.
Synonyms:exact_synonym: 3',6'-dihydroxy-3-oxo-3H-spiro[2-benzofuran-1,9'-xanthene]-5-carboxylic acid
 related_synonym: 4(5)-Carboxyfluorescein;   4-Carboxyfluorescein;   5-FAM;   Formula=C21H12O7;   InChI=1S/C21H12O7/c22-11-2-5-15-17(8-11)27-18-9-12(23)3-6-16(18)21(15)14-4-1-10(19(24)25)7-13(14)20(26)28-21/h1-9,22-23H,(H,24,25);   InChIKey=NJYVEMPWNAYQQN-UHFFFAOYSA-N;   SMILES=OC(=O)c1ccc2c(c1)C(=O)OC21c2ccc(O)cc2Oc2cc(O)ccc12;   Spiro(isobenzofuran-1(3H),9'-(9H)xanthene)-5-carboxylic acid, 3',6-dihydroxy-3-oxo-
 xref: Beilstein:57037;   CAS:76823-03-5
 xref_mesh: MESH:C045132


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5-carboxyfluorescein term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc22a8 solute carrier family 22 member 8 increases transport
multiple interactions		 ISO SLC22A8 protein results in increased transport of 4-carboxyfluorescein
quercetin 3'-sulfate inhibits the reaction [SLC22A8 protein results in increased transport of 4-carboxyfluorescein]; quercetin 3-O-glucuronide analog inhibits the reaction [SLC22A8 protein results in increased transport of 4-carboxyfluorescein]; quercetin 3-O-glucuronide inhibits the reaction [SLC22A8 protein results in increased transport of 4-carboxyfluorescein]		 CTD PMID:21244849 NCBI chr 1:205,496,331...205,516,378
Ensembl chr 1:205,498,084...205,517,450 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19751
    role 19724
      application 19557
        dye 2950
          xanthene dye 86
            fluorescein (lactone form) 66
              5-carboxyfluorescein 1
                5(6)-carboxyfluorescein 0
                fluorescein-5-carbonyl group + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19751
    subatomic particle 19749
      composite particle 19749
        hadron 19749
          baryon 19749
            nucleon 19749
              atomic nucleus 19749
                atom 19749
                  main group element atom 19698
                    p-block element atom 19698
                      carbon group element atom 19644
                        carbon atom 19640
                          organic molecular entity 19640
                            organic group 18846
                              organic divalent group 18832
                                organodiyl group 18832
                                  carbonyl group 18799
                                    carbonyl compound 18799
                                      carboxylic acid 18515
                                        aromatic carboxylic acid 11797
                                          benzoic acids 11771
                                            fluorescein (acid form) 67
                                              fluorescein (lactone form) 66
                                                5-carboxyfluorescein 1
                                                  5(6)-carboxyfluorescein 0
                                                  fluorescein-5-carbonyl group + 0
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