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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:cyclopropanes
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Accession:CHEBI:51454 term browser browse the term
Definition:Cyclopropane and its derivatives formed by substitution.


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(+)-trans-(S)-allethrin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme decreases activity ISO bioallethrin results in decreased activity of ACE protein CTD PMID:32097678 NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822
JBrowse link
G Cat catalase decreases activity ISO bioallethrin results in decreased activity of CAT protein CTD PMID:32097678 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Ces1d carboxylesterase 1D increases metabolic processing ISO CES1 protein results in increased metabolism of bioallethrin CTD PMID:19249324 NCBI chr19:15,195,514...15,239,827
Ensembl chr19:15,033,108...15,239,821
JBrowse link
G Chrm4 cholinergic receptor, muscarinic 4 multiple interactions ISO [DDT co-treated with bioallethrin] results in increased expression of CHRM4 mRNA CTD PMID:10192214 NCBI chr 3:80,833,272...80,841,165
Ensembl chr 3:80,833,272...80,841,006
JBrowse link
G Glo1 glyoxalase 1 increases activity ISO bioallethrin results in increased activity of GLO1 protein CTD PMID:32097678 NCBI chr20:9,273,589...9,291,608
Ensembl chr20:9,273,594...9,291,610
JBrowse link
G Gsr glutathione-disulfide reductase decreases activity ISO bioallethrin results in decreased activity of GSR protein CTD PMID:32097678 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Ifng interferon gamma multiple interactions
decreases expression
affects expression
ISO [bioallethrin co-treated with Piperonyl Butoxide] results in increased expression of IFNG protein
bioallethrin results in decreased expression of IFNG mRNA
bioallethrin affects the expression of IFNG protein
CTD PMID:9860237, PMID:10414782, PMID:12755381 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Il4 interleukin 4 multiple interactions
affects expression
ISO [bioallethrin co-treated with Piperonyl Butoxide] results in increased expression of IL4 protein
bioallethrin affects the expression of IL4 protein
CTD PMID:9860237, PMID:10414782 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity ISO
EXP
bioallethrin results in increased activity of NR1I2 protein CTD PMID:19249324 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Scn10a sodium voltage-gated channel alpha subunit 10 affects activity EXP bioallethrin affects the activity of SCN10A protein CTD PMID:19766671 NCBI chr 8:128,298,593...128,416,896
Ensembl chr 8:128,298,594...128,416,650
JBrowse link
G Scn1b sodium voltage-gated channel beta subunit 1 multiple interactions EXP bioallethrin affects the reaction [[SCN2B protein co-treated with SCN1B protein co-treated with SCN8A protein mutant form] results in increased transport of Sodium] CTD PMID:22465659 NCBI chr 1:89,550,738...89,560,469
Ensembl chr 1:89,550,738...89,560,719
JBrowse link
G Scn2b sodium voltage-gated channel beta subunit 2 multiple interactions EXP bioallethrin affects the reaction [[SCN2B protein co-treated with SCN1B protein co-treated with SCN8A protein mutant form] results in increased transport of Sodium] CTD PMID:22465659 NCBI chr 8:49,419,003...49,431,110
Ensembl chr 8:49,418,965...49,427,689
JBrowse link
G Scn8a sodium voltage-gated channel alpha subunit 8 multiple interactions EXP bioallethrin affects the reaction [[SCN2B protein co-treated with SCN1B protein co-treated with SCN8A protein mutant form] results in increased transport of Sodium] CTD PMID:22465659 NCBI chr 7:142,575,629...142,683,659
Ensembl chr 7:142,575,672...142,684,114
JBrowse link
3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Esr1 estrogen receptor 1 decreases activity EXP 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropane carboxylic acid results in decreased activity of ESR1 protein CTD PMID:20410157 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Serpine1 serpin family E member 1 affects binding ISO 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropane carboxylic acid binds to SERPINE1 protein CTD PMID:32278787 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482
JBrowse link
G Tshb thyroid stimulating hormone subunit beta multiple interactions ISO [Insecticides results in increased abundance of 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropane carboxylic acid] which results in increased expression of TSHB protein CTD PMID:31284115 NCBI chr 2:205,207,799...205,215,199
Ensembl chr 2:205,207,799...205,212,681
JBrowse link
allethrin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator increases expression ISO Allethrins results in increased expression of BAX protein CTD PMID:24055895 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO
EXP
Allethrins results in decreased expression of BCL2 protein CTD PMID:24055895, PMID:25072698 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bglap bone gamma-carboxyglutamate protein multiple interactions ISO Allethrins inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA] CTD PMID:32473317 NCBI chr 2:187,741,770...187,748,445
Ensembl chr 2:187,741,770...187,742,747
JBrowse link
G Brdt bromodomain testis associated decreases expression EXP Allethrins results in decreased expression of BRDT mRNA CTD PMID:28181402 NCBI chr14:3,437,876...3,462,613
Ensembl chr14:3,405,995...3,462,629
JBrowse link
G Cacna1a calcium voltage-gated channel subunit alpha1 A multiple interactions EXP Allethrins inhibits the reaction [CACNA1A protein results in increased transport of Calcium] CTD PMID:14634047 NCBI chr19:25,453,236...25,749,550
Ensembl chr19:25,526,751...25,749,550
JBrowse link
G Cacna1c calcium voltage-gated channel subunit alpha1 C multiple interactions EXP Allethrins inhibits the reaction [CACNA1C protein results in increased transport of Calcium] CTD PMID:14634047 NCBI chr 4:150,635,808...151,270,790
Ensembl chr 4:150,641,066...150,829,913
JBrowse link
G Cacna1g calcium voltage-gated channel subunit alpha1 G multiple interactions EXP Allethrins inhibits the reaction [CACNA1G protein results in increased transport of Calcium] CTD PMID:14634047 NCBI chr10:82,129,071...82,197,828
Ensembl chr10:82,129,506...82,197,848
JBrowse link
G Casp3 caspase 3 increases activity
decreases expression
ISO
EXP
Allethrins results in increased activity of CASP3 protein
Allethrins results in decreased expression of CASP3 protein
CTD PMID:24055895, PMID:25072698 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Cat catalase affects activity EXP Allethrins affects the activity of CAT protein CTD PMID:23595975, PMID:25072698 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions EXP Allethrins results in increased expression of and results in increased activity of CYP2E1 protein CTD PMID:22080754 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions EXP Allethrins results in increased expression of and results in increased activity of CYP3A2 protein CTD PMID:22080754 NCBI chr12:11,641,500...11,677,818
Ensembl chr12:11,655,402...11,733,136
JBrowse link
G Ddx25 DEAD-box helicase 25 decreases expression EXP Allethrins results in decreased expression of DDX25 mRNA CTD PMID:28181402 NCBI chr 8:36,744,686...36,760,720
Ensembl chr 8:36,744,667...36,760,742
JBrowse link
G Defb22 defensin beta 22 decreases expression EXP Allethrins results in decreased expression of DEFB22 mRNA CTD PMID:23595975 NCBI chr 3:147,961,818...147,966,097
Ensembl chr 3:147,961,818...147,966,097
JBrowse link
G Hsf2 heat shock transcription factor 2 decreases expression EXP Allethrins results in decreased expression of HSF2 mRNA CTD PMID:28181402 NCBI chr20:38,935,820...38,963,444
Ensembl chr20:38,935,820...38,963,309
JBrowse link
G Il1b interleukin 1 beta increases expression ISO Allethrins results in increased expression of IL1B mRNA CTD PMID:24055895 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Ins2 insulin 2 multiple interactions ISO Allethrins inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; Allethrins inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA] CTD PMID:32473317 NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034
JBrowse link
G Kdm3a lysine demethylase 3A decreases expression EXP Allethrins results in decreased expression of KDM3A mRNA CTD PMID:28181402 NCBI chr 4:99,503,160...99,547,315
Ensembl chr 4:99,503,176...99,546,905
JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase decreases expression EXP Allethrins results in decreased expression of KIT mRNA CTD PMID:28181402 NCBI chr14:35,072,131...35,149,638
Ensembl chr14:35,072,108...35,149,610
JBrowse link
G Kitlg KIT ligand decreases expression EXP Allethrins results in decreased expression of KITLG mRNA CTD PMID:28181402 NCBI chr 7:42,269,784...42,351,054
Ensembl chr 7:42,269,784...42,351,054
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases expression EXP Allethrins results in increased expression of MAPK1 protein modified form CTD PMID:23595975 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases expression EXP Allethrins results in increased expression of MAPK3 protein modified form CTD PMID:23595975 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mmp9 matrix metallopeptidase 9 increases expression ISO Allethrins results in increased expression of MMP9 protein CTD PMID:24055895 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mtf1 metal-regulatory transcription factor 1 increases activity ISO Allethrins results in increased activity of MTF1 protein CTD PMID:20143881 NCBI chr 5:142,797,340...142,843,896
Ensembl chr 5:142,797,366...142,842,122
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor increases activity ISO Allethrins results in increased activity of MYC protein CTD PMID:20143881 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions EXP Allethrins binds to and results in increased activity of NR1I2 protein CTD PMID:31538121 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases activity ISO Allethrins results in increased activity of NR1I3 protein CTD PMID:28927721 NCBI chr13:89,585,072...89,591,278
Ensembl chr13:89,586,283...89,591,277
JBrowse link
G Ovol1 ovo like transcriptional repressor 1 decreases expression EXP Allethrins results in decreased expression of OVOL1 mRNA CTD PMID:28181402 NCBI chr 1:220,927,309...220,938,814
Ensembl chr 1:220,925,605...220,938,814
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions EXP Allethrins results in decreased expression of and results in increased cleavage of PARP1 protein CTD PMID:25072698 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases activity
increases expression
ISO Allethrins results in increased activity of PPARG protein
Allethrins results in increased expression of PPARG mRNA
CTD PMID:20143881, PMID:32473317 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Rara retinoic acid receptor, alpha increases activity ISO Allethrins results in increased activity of RARA protein CTD PMID:20143881 NCBI chr10:86,838,819...86,884,224
Ensembl chr10:86,860,685...86,884,210
JBrowse link
G Scn10a sodium voltage-gated channel alpha subunit 10 multiple interactions EXP Allethrins affects the reaction [SCN10A protein results in increased transport of Sodium] CTD PMID:16051293 NCBI chr 8:128,298,593...128,416,896
Ensembl chr 8:128,298,594...128,416,650
JBrowse link
G Sp1 Sp1 transcription factor increases activity ISO Allethrins results in increased activity of SP1 protein CTD PMID:20143881 NCBI chr 7:144,014,173...144,044,635
Ensembl chr 7:144,014,173...144,044,629
JBrowse link
G Sp7 Sp7 transcription factor multiple interactions ISO Allethrins inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA] CTD PMID:32473317 NCBI chr 7:143,957,316...143,967,488
Ensembl chr 7:143,958,858...143,967,484
JBrowse link
G Spag11bl sperm associated antigen 11b-like decreases expression EXP Allethrins results in decreased expression of SPAG11A mRNA CTD PMID:23595975 NCBI chr16:75,145,234...75,148,750
Ensembl chr16:75,145,401...75,147,415
JBrowse link
G Star steroidogenic acute regulatory protein decreases expression EXP Allethrins results in decreased expression of STAR mRNA CTD PMID:28181402 NCBI chr16:71,036,204...71,040,847
Ensembl chr16:71,036,204...71,040,847
JBrowse link
G Tgfb1 transforming growth factor, beta 1 decreases expression EXP Allethrins results in decreased expression of TGFB1 mRNA CTD PMID:23595975 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tnf tumor necrosis factor increases expression ISO Allethrins results in increased expression of TNF mRNA CTD PMID:24055895 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tp53 tumor protein p53 affects expression
decreases expression
increases expression
EXP Allethrins affects the expression of TP53 protein
Allethrins results in decreased expression of TP53 mRNA
Allethrins results in increased expression of TP53 mRNA
CTD PMID:22356257, PMID:23595975, PMID:25072698 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Wnt10b Wnt family member 10B increases expression ISO Allethrins results in increased expression of WNT10B mRNA CTD PMID:12437293 NCBI chr 7:140,448,284...140,466,159
Ensembl chr 7:140,448,465...140,454,268
JBrowse link
G Ybx2 Y box binding protein 2 decreases expression EXP Allethrins results in decreased expression of YBX2 mRNA CTD PMID:28181402 NCBI chr10:56,546,689...56,552,339
Ensembl chr10:56,546,710...56,551,863
JBrowse link
BAY 60-6583 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora2b adenosine A2B receptor multiple interactions EXP BAY 60-6583 binds to and results in increased activity of ADORA2B protein CTD PMID:19749167 NCBI chr10:48,569,563...48,586,366
Ensembl chr10:48,569,555...48,586,365
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 multiple interactions
increases expression
ISO 1-propyl-8-(4-sulfophenyl)xanthine inhibits the reaction [[BAY 60-6583 co-treated with cobaltous chloride] results in increased expression of CXCL12 protein]; 1-propyl-8-(4-sulfophenyl)xanthine inhibits the reaction [BAY 60-6583 results in increased expression of CXCL12 protein]; [BAY 60-6583 co-treated with cobaltous chloride] results in increased expression of CXCL12 protein CTD PMID:27590504 NCBI chr 4:149,261,044...149,273,891
Ensembl chr 4:149,261,044...149,273,891
JBrowse link
G Fgf2 fibroblast growth factor 2 multiple interactions
increases expression
ISO 1-propyl-8-(4-sulfophenyl)xanthine inhibits the reaction [BAY 60-6583 results in increased expression of FGF2 protein]; [BAY 60-6583 co-treated with cobaltous chloride] results in increased expression of FGF2 protein CTD PMID:27590504 NCBI chr 2:124,081,072...124,134,133
Ensembl chr 2:124,081,072...124,134,681
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation ISO BAY 60-6583 results in increased phosphorylation of MAPK1 protein CTD PMID:27590504 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation ISO BAY 60-6583 results in increased phosphorylation of MAPK3 protein CTD PMID:27590504 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
bifenthrin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1b ATP-binding cassette, subfamily B (MDR/TAP), member 1B increases expression ISO bifenthrin results in increased expression of ABCB1B mRNA CTD PMID:26071804 NCBI chr 4:22,225,123...22,307,577
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Ache acetylcholinesterase multiple interactions
decreases expression
EXP bifenthrin results in decreased expression of and results in decreased activity of ACHE protein
bifenthrin results in decreased expression of ACHE mRNA
CTD PMID:29775722 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
JBrowse link
G Adh1 alcohol dehydrogenase 1 (class I) increases expression ISO bifenthrin results in increased expression of ADH1 mRNA CTD PMID:26071804 NCBI chr 2:243,550,655...243,562,243
Ensembl chr 2:243,550,627...243,687,857
JBrowse link
G Adh5 alcohol dehydrogenase 5 (class III), chi polypeptide increases expression ISO bifenthrin results in increased expression of ADH5 mRNA CTD PMID:26071804 NCBI chr 2:243,728,500...243,740,907
Ensembl chr 2:243,700,784...243,740,899
JBrowse link
G Ahr aryl hydrocarbon receptor increases expression ISO bifenthrin results in increased expression of AHR mRNA CTD PMID:26071804 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 increases expression ISO bifenthrin results in increased expression of ALDH1A1 mRNA CTD PMID:26071804 NCBI chr 1:238,222,689...238,264,381
Ensembl chr 1:238,222,521...238,264,330
JBrowse link
G Alox12 arachidonate 12-lipoxygenase, 12S type decreases expression ISO bifenthrin results in decreased expression of ALOX12 mRNA CTD PMID:26071804 NCBI chr10:56,851,734...56,864,049
Ensembl chr10:56,851,734...56,864,005
JBrowse link
G Alox15 arachidonate 15-lipoxygenase increases expression ISO bifenthrin results in increased expression of ALOX15 mRNA CTD PMID:26071804 NCBI chr10:56,953,692...56,962,145
Ensembl chr10:56,953,691...56,962,161
JBrowse link
G Alpl alkaline phosphatase, biomineralization associated multiple interactions ISO bifenthrin inhibits the reaction [Aldosterone results in increased expression of ALPL mRNA] CTD PMID:29149346 NCBI chr 5:156,086,496...156,141,513
Ensembl chr 5:156,086,497...156,141,537
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 increases expression ISO bifenthrin results in increased expression of APAF1 mRNA CTD PMID:26071804, PMID:32408700 NCBI chr 7:31,699,309...31,784,192
Ensembl chr 7:31,699,885...31,784,192
JBrowse link
G Apoe apolipoprotein E increases expression ISO bifenthrin results in increased expression of APOE mRNA CTD PMID:26071804 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
JBrowse link
G Areg amphiregulin multiple interactions EXP bifenthrin inhibits the reaction [CGA protein results in increased expression of AREG mRNA] CTD PMID:21251947 NCBI chr14:18,521,921...18,531,179
Ensembl chr14:18,521,930...18,531,179
JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator increases expression ISO bifenthrin results in increased expression of ARNT mRNA CTD PMID:26071804 NCBI chr 2:196,594,178...196,651,486
Ensembl chr 2:196,594,303...196,651,179
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO bifenthrin results in increased expression of BAX mRNA CTD PMID:32408700 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO bifenthrin results in decreased expression of BCL2 mRNA CTD PMID:26071804, PMID:27916261, PMID:32408700 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bid BH3 interacting domain death agonist increases expression ISO bifenthrin results in increased expression of BID mRNA CTD PMID:26071804, PMID:32408700 NCBI chr 4:153,439,812...153,465,247
Ensembl chr 4:153,442,218...153,465,203
JBrowse link
G Brca1 BRCA1, DNA repair associated affects binding ISO bifenthrin binds to BRCA1 protein CTD PMID:32278787 NCBI chr10:89,394,821...89,455,093
Ensembl chr10:89,394,803...89,454,681
JBrowse link
G Casp3 caspase 3 increases activity
increases expression
ISO bifenthrin results in increased activity of CASP3 protein
bifenthrin results in increased expression of CASP3 mRNA
CTD PMID:26071804, PMID:27916261, PMID:32408700 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp8 caspase 8 increases activity
decreases expression
ISO bifenthrin results in increased activity of CASP8 protein
bifenthrin results in decreased expression of CASP8 mRNA
CTD PMID:26071804 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 increases expression ISO bifenthrin results in increased expression of CASP9 mRNA CTD PMID:32408700 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cat catalase multiple interactions
decreases activity
decreases expression
increases expression
affects activity
ISO
EXP
Quercetin inhibits the reaction [bifenthrin results in decreased activity of CAT protein]; Rutin inhibits the reaction [bifenthrin results in decreased activity of CAT protein]
bifenthrin results in decreased expression of CAT protein
bifenthrin analog results in increased expression of CAT mRNA; bifenthrin results in increased expression of CAT mRNA
bifenthrin affects the activity of CAT protein; bifenthrin analog affects the activity of CAT protein
CTD PMID:19833193, PMID:23172818, PMID:25149237, PMID:27916261, PMID:29775722, PMID:29793499, PMID:30102949, PMID:32061760, PMID:32408700 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Ccne1 cyclin E1 multiple interactions EXP bifenthrin inhibits the reaction [CGA protein results in increased expression of CCNE1 mRNA] CTD PMID:21251947 NCBI chr 1:94,485,830...94,495,112
Ensembl chr 1:94,485,832...94,494,980
JBrowse link
G Cd36 CD36 molecule increases expression ISO bifenthrin results in increased expression of CD36 mRNA CTD PMID:29554630 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions EXP bifenthrin inhibits the reaction [CGA protein results in increased expression of CDKN1A mRNA] CTD PMID:21251947 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta multiple interactions EXP bifenthrin inhibits the reaction [CGA protein results in increased expression of CEBPB mRNA] CTD PMID:21251947 NCBI chr 3:164,424,502...164,425,933
Ensembl chr 3:164,424,515...164,425,910
JBrowse link
G Ces2h carboxylesterase 2H increases metabolic processing ISO CES2 protein results in increased metabolism of bifenthrin CTD PMID:19249324 NCBI chr19:37,052,555...37,067,176
Ensembl chr19:37,052,556...37,067,156
JBrowse link
G Cga glycoprotein hormones, alpha polypeptide multiple interactions
increases secretion
EXP
ISO
bifenthrin analog inhibits the reaction [CGA protein results in increased abundance of Progesterone]; bifenthrin analog inhibits the reaction [CGA protein results in increased secretion of Dinoprostone]; bifenthrin analog inhibits the reaction [CGA results in increased expression of CYP11A1 mRNA]; bifenthrin analog inhibits the reaction [CGA results in increased expression of DBI mRNA]; bifenthrin analog inhibits the reaction [CGA results in increased expression of PTGS2 mRNA]; bifenthrin analog inhibits the reaction [CGA results in increased expression of STAR mRNA]; bifenthrin analog inhibits the reaction [CGA results in increased expression of TSPO mRNA]; bifenthrin inhibits the reaction [CGA protein results in increased expression of AREG mRNA]; bifenthrin inhibits the reaction [CGA protein results in increased expression of CCNE1 mRNA]; bifenthrin inhibits the reaction [CGA protein results in increased expression of CDKN1A mRNA]; bifenthrin inhibits the reaction [CGA protein results in increased expression of CEBPB mRNA]; bifenthrin inhibits the reaction [CGA protein results in increased expression of CYP11A1 mRNA]; bifenthrin inhibits the reaction [CGA protein results in increased expression of CYP19A1 mRNA]; bifenthrin inhibits the reaction [CGA protein results in increased expression of EREG mRNA]; bifenthrin inhibits the reaction [CGA protein results in increased expression of PGR mRNA]; bifenthrin inhibits the reaction [CGA protein results in increased expression of PTGS2 mRNA]; bifenthrin inhibits the reaction [CGA protein results in increased expression of RUNX1 mRNA]; bifenthrin inhibits the reaction [CGA protein results in increased expression of STAR mRNA]; bifenthrin inhibits the reaction [CGA protein results in increased expression of SULT1E1 mRNA]; bifenthrin inhibits the reaction [CGA protein results in increased expression of TGFB1 mRNA]; bifenthrin inhibits the reaction [CGA protein results in increased secretion of Dinoprostone]
fulvestrant inhibits the reaction [bifenthrin results in increased secretion of CGA protein]
CTD PMID:21251947, PMID:21871944, PMID:24938463 NCBI chr 5:50,362,491...50,393,368
Ensembl chr 5:50,381,244...50,393,367
JBrowse link
G Chat choline O-acetyltransferase decreases expression EXP bifenthrin results in decreased expression of CHAT mRNA CTD PMID:29775722 NCBI chr16:8,576,858...8,686,131
Ensembl chr16:8,577,840...8,686,131
JBrowse link
G Chrm1 cholinergic receptor, muscarinic 1 decreases expression EXP bifenthrin results in decreased expression of CHRM1 mRNA CTD PMID:29775722 NCBI chr 1:224,869,087...224,885,101
Ensembl chr 1:224,882,439...224,884,205
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A decreases expression ISO bifenthrin results in decreased expression of CPT1A mRNA CTD PMID:29554630 NCBI chr 1:218,568,157...218,629,679
Ensembl chr 1:218,569,510...218,629,678
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 decreases expression ISO bifenthrin results in decreased expression of CXCL1 mRNA CTD PMID:28251819 NCBI chr14:18,820,168...18,839,659
Ensembl chr14:18,820,168...18,839,595
JBrowse link
G Cyb5r3 cytochrome b5 reductase 3 increases expression ISO bifenthrin results in increased expression of CYB5R3 mRNA CTD PMID:26071804 NCBI chr 7:124,024,003...124,041,564
Ensembl chr 7:124,023,995...124,041,594
JBrowse link
G Cycs cytochrome c, somatic increases expression ISO bifenthrin results in increased expression of CYCS mRNA CTD PMID:32408700 NCBI chr 4:80,331,226...80,333,326
Ensembl chr 4:80,331,227...80,333,326
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 multiple interactions
decreases expression
EXP
ISO
bifenthrin analog inhibits the reaction [CGA results in increased expression of CYP11A1 mRNA]; bifenthrin inhibits the reaction [CGA protein results in increased expression of CYP11A1 mRNA]
bifenthrin results in decreased expression of CYP11A1 mRNA
CTD PMID:21251947, PMID:21871944, PMID:23994515, PMID:24449165, PMID:32408700 NCBI chr 8:62,798,317...62,809,848
Ensembl chr 8:62,779,875...62,809,893
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 increases expression
decreases expression
ISO bifenthrin results in increased expression of CYP17A1 mRNA
bifenthrin results in decreased expression of CYP17A1 mRNA
CTD PMID:23994515, PMID:24449165, PMID:24938463, PMID:26071804, PMID:32408700 NCBI chr 1:266,422,127...266,429,947
Ensembl chr 1:266,422,132...266,428,239
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 multiple interactions
increases expression
EXP
ISO
bifenthrin inhibits the reaction [CGA protein results in increased expression of CYP19A1 mRNA]
bifenthrin results in increased expression of CYP19A1 mRNA
CTD PMID:21251947, PMID:24938463 NCBI chr 8:58,744,849...58,772,408
Ensembl chr 8:58,744,849...58,772,408
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases activity
decreases expression
EXP
ISO
bifenthrin results in increased activity of CYP1A1 protein
bifenthrin results in decreased expression of CYP1A1 mRNA
CTD PMID:20009351, PMID:26071804 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 increases expression ISO bifenthrin results in increased expression of CYP2C29 mRNA CTD PMID:26071804 NCBI chr 1:147,236,480...147,307,988 JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases expression ISO bifenthrin results in increased expression of CYP2E1 mRNA CTD PMID:26071804 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Cyp4b1 cytochrome P450, family 4, subfamily b, polypeptide 1 decreases expression ISO bifenthrin results in decreased expression of CYP4B1 mRNA CTD PMID:26071804 NCBI chr 5:134,508,728...134,526,103
Ensembl chr 5:134,508,730...134,526,089
JBrowse link
G Dbi diazepam binding inhibitor, acyl-CoA binding protein multiple interactions EXP bifenthrin analog inhibits the reaction [CGA results in increased expression of DBI mRNA] CTD PMID:21871944 NCBI chr13:36,147,667...36,156,076
Ensembl chr13:36,117,119...36,174,908
JBrowse link
G Ephx1 epoxide hydrolase 1 increases expression ISO bifenthrin results in increased expression of EPHX1 mRNA CTD PMID:26071804 NCBI chr13:99,271,390...99,300,580
Ensembl chr13:99,271,366...99,300,579
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 affects binding ISO bifenthrin binds to ERBB2 protein CTD PMID:32278787 NCBI chr10:86,367,596...86,391,728
Ensembl chr10:86,367,596...86,391,728
JBrowse link
G Ereg epiregulin multiple interactions EXP bifenthrin inhibits the reaction [CGA protein results in increased expression of EREG mRNA] CTD PMID:21251947 NCBI chr14:18,577,620...18,591,395
Ensembl chr14:18,576,355...18,591,394
JBrowse link
G Esr1 estrogen receptor 1 decreases expression
affects binding
ISO bifenthrin results in decreased expression of ESR1 mRNA
bifenthrin binds to ESR1 protein
CTD PMID:20097460, PMID:32278787 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Faim Fas apoptotic inhibitory molecule decreases expression ISO bifenthrin results in decreased expression of FAIM mRNA CTD PMID:26071804 NCBI chr 8:107,225,119...107,247,228
Ensembl chr 8:107,225,212...107,241,224
Ensembl chr 8:107,225,212...107,241,224
JBrowse link
G Faslg Fas ligand decreases expression ISO bifenthrin results in decreased expression of FASL mRNA CTD PMID:26071804 NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705
JBrowse link
G Fasn fatty acid synthase increases expression
decreases expression
ISO bifenthrin results in increased expression of FASN mRNA
bifenthrin results in decreased expression of FASN mRNA
CTD PMID:29554630, PMID:32408700 NCBI chr10:109,987,735...110,005,901
Ensembl chr10:109,987,735...110,005,901
JBrowse link
G Fbp1 fructose-bisphosphatase 1 increases expression ISO bifenthrin results in increased expression of FBP1 mRNA CTD PMID:26071804 NCBI chr17:396,175...417,480
Ensembl chr17:396,180...417,480
JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 affects binding ISO bifenthrin binds to FGFR2 protein CTD PMID:32278787 NCBI chr 1:200,590,951...200,696,946
Ensembl chr 1:200,590,953...200,696,928
JBrowse link
G Ggt1 gamma-glutamyltransferase 1 increases expression ISO bifenthrin results in increased expression of GGT1 mRNA CTD PMID:26071804 NCBI chr20:14,019,723...14,045,781
Ensembl chr20:14,019,723...14,025,068
JBrowse link
G Gnrh1 gonadotropin releasing hormone 1 increases expression ISO bifenthrin results in increased expression of GNRH1 mRNA CTD PMID:24938463 NCBI chr15:44,441,856...44,446,064
Ensembl chr15:44,442,555...44,442,875
Ensembl chr15:44,442,555...44,442,875
JBrowse link
G Gnrhr gonadotropin releasing hormone receptor increases expression ISO bifenthrin results in increased expression of GNRHR mRNA CTD PMID:24938463 NCBI chr14:23,480,462...23,498,450
Ensembl chr14:23,480,462...23,498,450
JBrowse link
G Gpi glucose-6-phosphate isomerase increases expression ISO bifenthrin results in increased expression of GPI1 mRNA CTD PMID:26071804 NCBI chr 1:90,063,411...90,091,287
Ensembl chr 1:90,063,411...90,091,287
JBrowse link
G Gpx1 glutathione peroxidase 1 increases expression
decreases expression
ISO bifenthrin results in increased expression of GPX1 mRNA
bifenthrin results in decreased expression of GPX1 mRNA
CTD PMID:26071804, PMID:27916261 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G Gpx2 glutathione peroxidase 2 increases expression
decreases expression
ISO bifenthrin results in increased expression of GPX2 mRNA
bifenthrin results in decreased expression of GPX2 mRNA
CTD PMID:26071804, PMID:27916261 NCBI chr 6:99,839,960...99,843,245
Ensembl chr 6:99,839,960...99,843,245
JBrowse link
G Gpx3 glutathione peroxidase 3 increases expression ISO bifenthrin results in increased expression of GPX3 mRNA CTD PMID:26071804 NCBI chr10:40,247,436...40,255,423
Ensembl chr10:40,247,436...40,255,422
JBrowse link
G Gsta2 glutathione S-transferase alpha 2 increases expression ISO bifenthrin results in increased expression of GSTA1 mRNA CTD PMID:26071804, PMID:27916261 NCBI chr 8:85,640,081...85,645,621 JBrowse link
G Gsta3 glutathione S-transferase alpha 3 increases expression ISO bifenthrin results in increased expression of GSTA3 mRNA CTD PMID:26071804 NCBI chr 9:27,357,490...27,417,023
Ensembl chr 9:27,402,381...27,417,023
JBrowse link
G Gsta6 glutathione S-transferase alpha 6 increases expression ISO bifenthrin results in increased expression of GSTA1 mRNA CTD PMID:26071804, PMID:27916261 NCBI chr 9:27,475,273...27,533,939
Ensembl chr 9:27,475,273...27,511,176
JBrowse link
G Gstm1 glutathione S-transferase mu 1 increases expression ISO bifenthrin results in increased expression of GSTM1 mRNA CTD PMID:26071804 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G Gstm2 glutathione S-transferase mu 2 increases expression ISO bifenthrin results in increased expression of GSTM2 mRNA CTD PMID:26071804 NCBI chr 2:210,778,041...210,782,807
Ensembl chr 2:210,720,704...210,782,856
JBrowse link
G Gstm5 glutathione S-transferase, mu 5 increases expression ISO bifenthrin results in increased expression of GSTM5 mRNA CTD PMID:26071804 NCBI chr 2:210,685,338...210,688,133
Ensembl chr 2:210,685,197...210,688,272
JBrowse link
G Gstp1 glutathione S-transferase pi 1 increases expression ISO bifenthrin results in increased expression of GSTP1 mRNA CTD PMID:26071804 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Hk2 hexokinase 2 increases expression ISO bifenthrin results in increased expression of HK2 mRNA CTD PMID:26071804 NCBI chr 4:113,559,396...113,609,897
Ensembl chr 4:113,559,427...113,610,243
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO bifenthrin analog results in increased expression of HMOX1 mRNA; bifenthrin results in increased expression of HMOX1 mRNA CTD PMID:25149237, PMID:27916261 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hsd17b1 hydroxysteroid (17-beta) dehydrogenase 1 decreases expression ISO bifenthrin results in decreased expression of HSD17B1 mRNA CTD PMID:24938463 NCBI chr10:88,987,558...88,989,758
Ensembl chr10:88,987,558...88,989,757
JBrowse link
G Hsd17b3 hydroxysteroid (17-beta) dehydrogenase 3 decreases expression ISO bifenthrin results in decreased expression of HSD17B3 mRNA CTD PMID:26071804 NCBI chr17:1,579,319...1,610,745
Ensembl chr17:1,579,319...1,610,745
JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 decreases expression ISO bifenthrin results in decreased expression of HSD3B1 mRNA CTD PMID:32408700
G Hsd3b2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 increases expression ISO bifenthrin results in increased expression of HSD3B2 mRNA CTD PMID:24938463 NCBI chr 2:200,712,895...200,722,429
Ensembl chr 2:202,341,422...202,350,929
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A decreases expression ISO bifenthrin results in decreased expression of HSPA1A protein CTD PMID:16271832 NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression ISO bifenthrin results in increased expression of HSPA5 protein CTD PMID:16271832 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 decreases expression ISO bifenthrin results in decreased expression of HSPA8 protein CTD PMID:16271832 NCBI chr 8:44,989,401...44,993,261
Ensembl chr 8:44,990,014...44,993,179
JBrowse link
G Hspb2 heat shock protein family B (small) member 2 decreases expression ISO bifenthrin results in decreased expression of HSPB2 protein CTD PMID:16271832 NCBI chr 8:55,176,648...55,178,227
Ensembl chr 8:55,176,847...55,177,818
JBrowse link
G Il1b interleukin 1 beta decreases expression
increases expression
multiple interactions
ISO
EXP
bifenthrin results in decreased expression of IL1B mRNA
bifenthrin results in increased expression of IL1B mRNA
bifenthrin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL1B mRNA]
CTD PMID:27916261, PMID:28251819, PMID:30102949 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il2 interleukin 2 increases expression ISO bifenthrin results in increased expression of IL2 mRNA CTD PMID:23172818 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
JBrowse link
G Il4 interleukin 4 increases expression ISO bifenthrin results in increased expression of IL4 mRNA CTD PMID:23172818 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Il6 interleukin 6 decreases expression
increases expression
multiple interactions
ISO
EXP
bifenthrin results in decreased expression of IL6 mRNA
bifenthrin results in increased expression of IL6 protein
bifenthrin results in increased expression of IL6 mRNA
bifenthrin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL6 mRNA]
CTD PMID:27916261, PMID:28251819, PMID:29793499, PMID:30102949, PMID:32061760 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Ldlr low density lipoprotein receptor decreases expression ISO bifenthrin results in decreased expression of LDLR mRNA CTD PMID:24449165, PMID:32408700 NCBI chr 8:22,750,425...22,773,305
Ensembl chr 8:22,750,336...22,774,903
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation ISO bifenthrin analog results in increased phosphorylation of MAPK1 protein CTD PMID:19442700 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation ISO bifenthrin analog results in increased phosphorylation of MAPK3 protein CTD PMID:19442700 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mgst2 microsomal glutathione S-transferase 2 decreases expression ISO bifenthrin results in decreased expression of MGST2 mRNA CTD PMID:26071804 NCBI chr 2:140,708,396...140,727,381
Ensembl chr 2:140,708,397...140,727,281
JBrowse link
G Mgst3 microsomal glutathione S-transferase 3 increases expression ISO bifenthrin results in increased expression of MGST3 mRNA CTD PMID:26071804 NCBI chr13:85,601,499...85,622,392
Ensembl chr13:85,601,499...85,622,314
JBrowse link
G Mir122 microRNA 122 increases expression ISO bifenthrin results in increased expression of MIR122 mRNA CTD PMID:32408700 NCBI chr18:60,755,285...60,755,369 JBrowse link
G Mir17 microRNA 17 decreases expression ISO bifenthrin results in decreased expression of MIR17 mRNA CTD PMID:32408700 NCBI chr15:100,179,879...100,179,962
Ensembl chr15:100,179,879...100,179,962
JBrowse link
G Mir34b microRNA 34b decreases expression ISO bifenthrin results in decreased expression of MIR34B mRNA CTD PMID:32408700 NCBI chr 8:55,492,542...55,492,625
Ensembl chr 8:55,492,542...55,492,625
JBrowse link
G Mir34c microRNA 34c decreases expression ISO bifenthrin results in decreased expression of MIR34C mRNA CTD PMID:32408700 NCBI chr 8:55,492,024...55,492,100
Ensembl chr 8:55,492,024...55,492,100
JBrowse link
G Mir449a microRNA 449a decreases expression ISO bifenthrin results in decreased expression of MIR449A mRNA CTD PMID:32408700 NCBI chr 2:44,897,601...44,897,691
Ensembl chr 2:44,897,601...44,897,691
JBrowse link
G Mir449c microRNA 449c decreases expression ISO bifenthrin results in decreased expression of MIR449C mRNA CTD PMID:32408700 NCBI chr 2:44,896,066...44,896,164
Ensembl chr 2:44,896,066...44,896,164
JBrowse link
G Mt2A metallothionein 2A increases expression ISO bifenthrin results in increased expression of MT2 mRNA CTD PMID:26071804 NCBI chr19:11,307,966...11,308,740
Ensembl chr19:11,307,967...11,308,740
JBrowse link
G Mt3 metallothionein 3 increases expression ISO bifenthrin results in increased expression of MT3 mRNA CTD PMID:26071804 NCBI chr19:11,324,708...11,326,112
Ensembl chr19:11,324,698...11,326,139
JBrowse link
G Mthfr methylenetetrahydrofolate reductase increases expression ISO bifenthrin results in increased expression of MTHFR mRNA CTD PMID:26071804 NCBI chr 5:164,844,642...164,864,360
Ensembl chr 5:164,845,925...164,860,910
JBrowse link
G Nat1 N-acetyltransferase 1 increases expression ISO bifenthrin results in increased expression of NAT1 mRNA CTD PMID:26071804 NCBI chr16:23,970,742...23,991,573
Ensembl chr16:23,970,743...23,991,573
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 decreases expression
increases expression
EXP
ISO
bifenthrin results in decreased expression of NFE2L2 mRNA; bifenthrin results in decreased expression of NFE2L2 protein
bifenthrin results in increased expression of NFE2L2 mRNA; bifenthrin results in increased expression of NFE2L2 protein
CTD PMID:29775722, PMID:29793499, PMID:30102949, PMID:32061760 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 decreases expression
affects binding
ISO bifenthrin results in decreased expression of NQO1 mRNA
bifenthrin binds to NQO1 protein
CTD PMID:27916261, PMID:32278787 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions ISO bifenthrin inhibits the reaction [pregna-4,17-diene-3,16-dione results in decreased activity of NR1H4 protein] CTD PMID:25257666 NCBI chr 7:30,003,429...30,162,095
Ensembl chr 7:30,003,429...30,162,056
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity
increases expression
affects binding
ISO
EXP
bifenthrin results in increased activity of NR1I2 protein
bifenthrin results in increased expression of NR1I2 mRNA; bifenthrin results in increased expression of NR1I2 protein
bifenthrin binds to NR1I2 protein
CTD PMID:19249324, PMID:29554630 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 multiple interactions ISO bifenthrin inhibits the reaction [Hydrocortisone results in increased activity of NR3C1 protein] CTD PMID:26647222 NCBI chr18:31,728,373...32,704,022
Ensembl chr18:31,728,373...31,749,647
JBrowse link
G Nr3c2 nuclear receptor subfamily 3, group C, member 2 multiple interactions ISO bifenthrin inhibits the reaction [Aldosterone affects the localization of NR3C2 protein]; bifenthrin inhibits the reaction [Aldosterone results in increased activity of NR3C2 protein] CTD PMID:29149346 NCBI chr19:34,408,275...34,761,003
Ensembl chr19:34,448,289...34,752,695
JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 multiple interactions EXP bifenthrin inhibits the reaction [Hydrocortisone results in increased expression of PCK1 mRNA] CTD PMID:26647222 NCBI chr 3:171,213,936...171,219,885
Ensembl chr 3:171,213,936...171,219,871
JBrowse link
G Pgr progesterone receptor multiple interactions
increases expression
EXP
ISO
bifenthrin inhibits the reaction [CGA protein results in increased expression of PGR mRNA]
fulvestrant inhibits the reaction [bifenthrin results in increased expression of PGR mRNA]
bifenthrin results in increased expression of PGR; bifenthrin results in increased expression of PGR mRNA
CTD PMID:21251947, PMID:24938463 NCBI chr 8:7,128,656...7,187,796
Ensembl chr 8:7,128,656...7,187,796
JBrowse link
G Pklr pyruvate kinase L/R decreases expression ISO bifenthrin results in decreased expression of PKLR mRNA CTD PMID:26071804 NCBI chr 2:188,449,158...188,458,034
Ensembl chr 2:188,449,210...188,459,592
JBrowse link
G Pkm pyruvate kinase M1/2 increases expression ISO bifenthrin results in increased expression of PKM mRNA CTD PMID:26071804 NCBI chr 8:64,480,963...64,502,957
Ensembl chr 8:64,481,172...64,502,722
JBrowse link
G Pon1 paraoxonase 1 increases expression ISO bifenthrin results in increased expression of PON1 mRNA CTD PMID:26071804 NCBI chr 4:30,249,749...30,276,297
Ensembl chr 4:30,249,742...30,276,372
JBrowse link
G Pon3 paraoxonase 3 increases expression ISO bifenthrin results in increased expression of PON3 mRNA CTD PMID:26071804 NCBI chr 4:30,311,981...30,338,679
Ensembl chr 4:30,311,982...30,338,679
JBrowse link
G Ppard peroxisome proliferator-activated receptor delta affects binding ISO bifenthrin binds to PPARD protein CTD PMID:32278787 NCBI chr20:7,818,289...7,883,482
Ensembl chr20:7,818,289...7,885,333
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases expression ISO bifenthrin results in increased expression of PPARG mRNA CTD PMID:29554630 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Ptges prostaglandin E synthase increases expression EXP
ISO
bifenthrin results in increased expression of PTGES mRNA; bifenthrin results in increased expression of PTGES protein CTD PMID:29775722, PMID:29793499, PMID:30102949, PMID:32061760 NCBI chr 3:9,727,408...9,738,752
Ensembl chr 3:9,727,408...9,738,752
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases expression
EXP
ISO
bifenthrin analog inhibits the reaction [CGA results in increased expression of PTGS2 mRNA]; bifenthrin inhibits the reaction [CGA protein results in increased expression of PTGS2 mRNA]; bifenthrin inhibits the reaction [Colforsin results in increased expression of PTGS2 mRNA]
bifenthrin results in increased expression of PTGS2 mRNA; bifenthrin results in increased expression of PTGS2 protein
CTD PMID:21251947, PMID:21871944, PMID:29775722, PMID:29793499, PMID:30102949, PMID:32061760 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit increases expression EXP
ISO
bifenthrin results in increased expression of RELA mRNA; bifenthrin results in increased expression of RELA protein CTD PMID:29775722, PMID:29793499, PMID:30102949, PMID:32061760 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Rora RAR-related orphan receptor A affects binding ISO bifenthrin binds to RORA protein CTD PMID:32278787 NCBI chr 8:75,515,886...75,616,477
Ensembl chr 8:75,516,904...75,607,212
JBrowse link
G Rorc RAR-related orphan receptor C affects binding ISO bifenthrin binds to RORC protein CTD PMID:32278787 NCBI chr 2:195,612,471...195,636,797
Ensembl chr 2:195,617,021...195,637,630
JBrowse link
G Runx1 RUNX family transcription factor 1 multiple interactions EXP bifenthrin inhibits the reaction [CGA protein results in increased expression of RUNX1 mRNA] CTD PMID:21251947 NCBI chr11:32,765,147...33,003,061
Ensembl chr11:32,769,165...33,003,021
JBrowse link
G Scarb1 scavenger receptor class B, member 1 decreases expression ISO bifenthrin results in decreased expression of SCARB1 mRNA CTD PMID:23994515 NCBI chr12:36,694,952...36,761,445
Ensembl chr12:36,694,960...36,761,455
JBrowse link
G Scd stearoyl-CoA desaturase increases expression ISO bifenthrin results in increased expression of SCD mRNA CTD PMID:29554630 NCBI chr 1:264,159,966...264,173,061
Ensembl chr 1:264,160,129...264,172,729
JBrowse link
G Scn10a sodium voltage-gated channel alpha subunit 10 multiple interactions EXP bifenthrin affects the reaction [SCN10A protein results in increased transport of Sodium] CTD PMID:16051293 NCBI chr 8:128,298,593...128,416,896
Ensembl chr 8:128,298,594...128,416,650
JBrowse link
G Shbg sex hormone binding globulin affects binding ISO bifenthrin binds to SHBG protein CTD PMID:32278787 NCBI chr10:56,219,861...56,237,354
Ensembl chr10:56,219,858...56,223,245
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions
increases expression
EXP
ISO
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [bifenthrin analog results in increased expression of SOD1 protein]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [bifenthrin analog results in increased expression of SOD1 protein]
bifenthrin analog results in increased expression of SOD1 mRNA; bifenthrin results in increased expression of SOD1 mRNA
CTD PMID:22718203, PMID:25149237, PMID:27916261 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions
increases expression
EXP
ISO
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [bifenthrin analog results in increased expression of SOD2 protein]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [bifenthrin analog results in increased expression of SOD2 protein]
bifenthrin results in increased expression of SOD2 mRNA
CTD PMID:22718203, PMID:27916261 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase affects binding ISO bifenthrin binds to SRC protein CTD PMID:32278787 NCBI chr 3:153,547,807...153,595,643
Ensembl chr 3:153,580,861...153,595,642
JBrowse link
G Srd5a2 steroid 5 alpha-reductase 2 decreases expression ISO bifenthrin results in decreased expression of SRD5A2 mRNA CTD PMID:26071804 NCBI chr 6:25,279,635...25,315,501
Ensembl chr 6:25,279,626...25,315,511
JBrowse link
G Star steroidogenic acute regulatory protein multiple interactions
decreases expression
EXP
ISO
bifenthrin analog inhibits the reaction [CGA results in increased expression of STAR mRNA]; bifenthrin inhibits the reaction [CGA protein results in increased expression of STAR mRNA]
bifenthrin results in decreased expression of STAR mRNA
CTD PMID:21251947, PMID:21871944, PMID:23994515 NCBI chr16:71,036,204...71,040,847
Ensembl chr16:71,036,204...71,040,847
JBrowse link
G Sult1e1 sulfotransferase family 1E member 1 multiple interactions EXP bifenthrin inhibits the reaction [CGA protein results in increased expression of SULT1E1 mRNA] CTD PMID:21251947 NCBI chr14:22,070,861...22,089,264
Ensembl chr14:22,072,024...22,089,248
JBrowse link
G Tff1 trefoil factor 1 increases expression ISO bifenthrin results in increased expression of TFF1 mRNA CTD PMID:20097460 NCBI chr20:9,892,124...9,895,984
Ensembl chr20:9,892,124...9,895,984
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP bifenthrin inhibits the reaction [CGA protein results in increased expression of TGFB1 mRNA] CTD PMID:21251947 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tnf tumor necrosis factor increases expression
multiple interactions
decreases expression
ISO
EXP
bifenthrin results in increased expression of TNF mRNA
bifenthrin results in increased expression of TNF protein
bifenthrin results in increased expression of TNF mRNA; bifenthrin results in increased expression of TNF protein
bifenthrin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TNF mRNA]
bifenthrin results in decreased expression of TNF mRNA
CTD PMID:23172818, PMID:26071804, PMID:27916261, PMID:28251819, PMID:29775722, PMID:29793499, PMID:30102949, PMID:32061760, PMID:32408700 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tp53 tumor protein p53 increases expression
decreases expression
ISO bifenthrin results in increased expression of TRP53 mRNA
bifenthrin results in decreased expression of TRP53 mRNA
CTD PMID:20097460, PMID:26071804, PMID:27916261 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Tspo translocator protein multiple interactions
decreases expression
EXP
ISO
bifenthrin analog inhibits the reaction [CGA results in increased expression of TSPO mRNA]
bifenthrin results in decreased expression of TSPO mRNA
CTD PMID:21871944, PMID:23994515, PMID:24449165 NCBI chr 7:124,460,358...124,470,610
Ensembl chr 7:124,460,358...124,470,609
JBrowse link
bioresmethrin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ces1d carboxylesterase 1D multiple interactions
increases hydrolysis
increases metabolic processing
ISO
EXP
27-hydroxycholesterol inhibits the reaction [CES1 protein results in increased metabolism of bioresmethrin]
CES1 protein results in increased hydrolysis of bioresmethrin
CTD PMID:16387282, PMID:19249324, PMID:19761868 NCBI chr19:15,195,514...15,239,827
Ensembl chr19:15,033,108...15,239,821
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity
multiple interactions
ISO
EXP
bioresmethrin results in increased activity of NR1I2 protein
bioresmethrin binds to and results in increased activity of NR1I2 protein
CTD PMID:19249324, PMID:31538121 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions EXP bioresmethrin binds to and results in decreased activity of NR1I3 protein CTD PMID:31538121 NCBI chr13:89,585,072...89,591,278
Ensembl chr13:89,586,283...89,591,277
JBrowse link
calcipotriol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc3 ATP binding cassette subfamily C member 3 multiple interactions
increases expression
ISO VDR protein affects the reaction [calcipotriene results in increased expression of ABCC3 protein] CTD PMID:30419252 NCBI chr10:82,047,308...82,116,928
Ensembl chr10:82,047,863...82,117,109
JBrowse link
G Becn1 beclin 1 increases expression ISO calcipotriene results in increased expression of BECN1 protein CTD PMID:21228817 NCBI chr10:89,209,944...89,225,297
Ensembl chr10:89,209,940...89,225,297
JBrowse link
G Camp cathelicidin antimicrobial peptide multiple interactions ISO calcipotriene promotes the reaction [pterostilbene results in increased expression of CAMP mRNA]; calcipotriene promotes the reaction [resveratrol results in increased expression of CAMP mRNA] CTD PMID:24039193 NCBI chr 8:117,930,557...117,932,371
Ensembl chr 8:117,930,546...117,932,518
JBrowse link
G Crlf2 cytokine receptor-like factor 2 multiple interactions
increases expression
ISO lithol rubine BCA analog promotes the reaction [calcipotriene results in increased expression of CRLF2 mRNA]; lithol rubine BCA promotes the reaction [calcipotriene results in increased expression of CRLF2 mRNA] CTD PMID:29462589 NCBI chr14:1,456,843...1,461,543
Ensembl chr14:1,456,844...1,461,543
JBrowse link
G Cyp24a1 cytochrome P450, family 24, subfamily a, polypeptide 1 increases expression ISO calcipotriene results in increased expression of CYP24A1 mRNA CTD PMID:7530193 NCBI chr 3:168,097,484...168,111,920
Ensembl chr 3:168,097,485...168,111,920
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 decreases expression
multiple interactions
ISO calcipotriene results in decreased expression of CYP7A1 protein
calcipotriene inhibits the reaction [VDR protein affects the expression of CYP7A1 protein]
CTD PMID:30419252 NCBI chr 5:19,358,734...19,368,431
Ensembl chr 5:19,358,734...19,368,431
JBrowse link
G Flg filaggrin decreases expression ISO calcipotriene results in decreased expression of FLG protein CTD PMID:7508215 NCBI chr 2:193,565,401...193,574,297 JBrowse link
G Il13 interleukin 13 multiple interactions ISO [lithol rubine BCA analog results in increased susceptibility to calcipotriene] which results in increased expression of IL13 mRNA; [lithol rubine BCA results in increased susceptibility to calcipotriene] which results in increased expression of IL13 mRNA CTD PMID:29462589 NCBI chr10:38,982,909...38,985,466
Ensembl chr10:38,982,909...38,985,466
JBrowse link
G Il4 interleukin 4 multiple interactions ISO [lithol rubine BCA analog results in increased susceptibility to calcipotriene] which results in increased expression of IL4 mRNA; [lithol rubine BCA results in increased susceptibility to calcipotriene] which results in increased expression of IL4 mRNA CTD PMID:29462589 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Il5 interleukin 5 multiple interactions ISO [lithol rubine BCA analog results in increased susceptibility to calcipotriene] which results in increased expression of IL5 mRNA; [lithol rubine BCA results in increased susceptibility to calcipotriene] which results in increased expression of IL5 mRNA CTD PMID:29462589 NCBI chr10:39,066,716...39,069,587
Ensembl chr10:39,066,716...39,069,587
JBrowse link
G Ivl involucrin decreases expression ISO calcipotriene results in decreased expression of IVL protein CTD PMID:7508215 NCBI chr 2:192,761,171...192,773,346
Ensembl chr 2:192,761,538...192,763,577
JBrowse link
G Krt10 keratin 10 decreases expression ISO calcipotriene results in decreased expression of KRT10 protein CTD PMID:7508215 NCBI chr10:87,296,445...87,301,307
Ensembl chr10:87,296,451...87,300,736
JBrowse link
G Krt16 keratin 16 decreases expression ISO calcipotriene results in decreased expression of KRT16 protein CTD PMID:7508215 NCBI chr10:88,149,210...88,152,167
Ensembl chr10:88,149,345...88,152,064
JBrowse link
G Krt17 keratin 17 decreases expression ISO calcipotriene results in decreased expression of KRT17 protein CTD PMID:7508215 NCBI chr10:88,158,993...88,163,712
Ensembl chr10:88,118,001...88,163,723
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 decreases response to substance ISO MAPK8 gene mutant form results in decreased susceptibility to calcipotriene CTD PMID:24046278 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 increases expression ISO calcipotriene results in increased expression of NR0B2 protein CTD PMID:30419252 NCBI chr 5:151,776,004...151,779,319
Ensembl chr 5:151,776,004...151,779,319
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions ISO calcipotriene binds to and results in increased activity of NR1I3 protein alternative form CTD PMID:31312845 NCBI chr13:89,585,072...89,591,278
Ensembl chr13:89,586,283...89,591,277
JBrowse link
G Tnfsf4 TNF superfamily member 4 multiple interactions ISO [lithol rubine BCA analog results in increased susceptibility to calcipotriene] which results in increased expression of TNFSF4 mRNA; [lithol rubine BCA results in increased susceptibility to calcipotriene] which results in increased expression of TNFSF4 mRNA CTD PMID:29462589 NCBI chr13:79,269,973...79,293,775
Ensembl chr13:79,269,973...79,293,778
JBrowse link
G Tslp thymic stromal lymphopoietin increases expression
multiple interactions
increases secretion
ISO calcipotriene results in increased expression of TSLP mRNA
lithol rubine BCA analog promotes the reaction [calcipotriene results in increased expression of TSLP mRNA]; lithol rubine BCA analog promotes the reaction [calcipotriene results in increased secretion of TSLP protein]; lithol rubine BCA promotes the reaction [calcipotriene results in increased expression of TSLP mRNA]; lithol rubine BCA promotes the reaction [calcipotriene results in increased secretion of TSLP protein]
CTD PMID:16880407, PMID:29462589 NCBI chr18:25,613,601...25,618,066
Ensembl chr18:25,613,831...25,617,361
JBrowse link
G Vdr vitamin D receptor multiple interactions
increases expression
affects response to substance
ISO calcipotriene affects the reaction [Calcitriol binds to VDR protein]; calcipotriene inhibits the reaction [VDR protein affects the expression of CYP7A1 protein]; VDR protein affects the reaction [calcipotriene results in increased expression of ABCC3 protein]
calcipotriene results in increased expression of VDR protein
VDR promoter SNP affects the susceptibility to calcipotriene
CTD PMID:7530193, PMID:15864137, PMID:30419252 NCBI chr 7:139,344,452...139,394,138
Ensembl chr 7:139,342,063...139,394,166
JBrowse link
ciprofibrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 decreases expression ISO ciprofibrate results in decreased expression of ABCB11 protein CTD PMID:12381268 NCBI chr 3:55,480,024...55,587,946
Ensembl chr 3:55,480,024...55,587,946
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A increases expression ISO ciprofibrate results in increased expression of ABCB1A mRNA CTD PMID:12381268 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcb1b ATP-binding cassette, subfamily B (MDR/TAP), member 1B increases expression ISO ciprofibrate results in increased expression of ABCB1B mRNA CTD PMID:12381268 NCBI chr 4:22,225,123...22,307,577
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcb4 ATP binding cassette subfamily B member 4 increases expression ISO ciprofibrate results in increased expression of ABCB4 mRNA; ciprofibrate results in increased expression of ABCB4 protein CTD PMID:12381268 NCBI chr 4:22,133,984...22,192,687
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 multiple interactions
increases expression
ISO [ciprofibrate binds to PPARA protein] which results in increased expression of ABCC3 mRNA
ciprofibrate results in increased expression of ABCC3 mRNA
CTD PMID:15833929 NCBI chr10:82,047,308...82,116,928
Ensembl chr10:82,047,863...82,117,109
JBrowse link
G Acaa1a acetyl-CoA acyltransferase 1A increases expression ISO ciprofibrate results in increased expression of ACAA1A mRNA CTD PMID:12771043 NCBI chr 8:128,027,880...128,036,471
Ensembl chr 8:128,027,958...128,036,236
JBrowse link
G Acaa2 acetyl-CoA acyltransferase 2 increases expression EXP ciprofibrate results in increased expression of ACAA2 mRNA CTD PMID:27225895 NCBI chr18:70,733,872...70,762,395
Ensembl chr18:70,733,872...70,762,395
JBrowse link
G Acot1 acyl-CoA thioesterase 1 increases expression ISO
EXP
ciprofibrate results in increased expression of ACOT1 mRNA CTD PMID:27225895 NCBI chr 6:107,485,088...107,493,082
Ensembl chr 6:107,485,249...107,493,798
JBrowse link
G Acot2 acyl-CoA thioesterase 2 increases expression EXP
ISO
ciprofibrate results in increased expression of ACOT2 mRNA CTD PMID:27225895 NCBI chr 6:107,460,596...107,468,324
Ensembl chr 6:107,460,668...107,467,487
JBrowse link
G Acot3 acyl-CoA thioesterase 3 increases expression EXP
ISO
ciprofibrate results in increased expression of ACOT3 mRNA CTD PMID:27225895 NCBI chr 6:107,531,508...107,537,446
Ensembl chr 6:107,531,528...107,536,789
JBrowse link
G Acot4 acyl-CoA thioesterase 4 increases expression EXP
ISO
ciprofibrate results in increased expression of ACOT4 mRNA CTD PMID:27225895 NCBI chr 6:107,517,668...107,522,952
Ensembl chr 6:107,517,668...107,522,952
JBrowse link
G Acox1 acyl-CoA oxidase 1 increases activity
increases expression
multiple interactions
EXP
ISO
ciprofibrate results in increased activity of ACOX1 protein
ciprofibrate results in increased expression of ACOX1 mRNA
[ciprofibrate co-treated with Fatty Acids, Unsaturated deficiency] results in increased expression of ACOX1 mRNA
CTD PMID:8001245, PMID:11172741, PMID:12771043, PMID:19544052, PMID:24986865, PMID:27225895 NCBI chr10:104,724,534...104,748,003
Ensembl chr10:104,722,958...104,748,050
JBrowse link
G Acsl1 acyl-CoA synthetase long-chain family member 1 increases expression EXP ciprofibrate results in increased expression of ACSL1 mRNA CTD PMID:27225895 NCBI chr16:48,937,456...49,003,898
Ensembl chr16:48,937,456...49,003,246
JBrowse link
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 increases expression ISO ciprofibrate results in increased expression of ADAMTS1 mRNA CTD PMID:12771043 NCBI chr11:25,342,119...25,350,938
Ensembl chr11:25,342,126...25,350,974
JBrowse link
G Aig1 androgen-induced 1 increases expression ISO ciprofibrate results in increased expression of AIG1 mRNA CTD PMID:12771043 NCBI chr 1:7,816,841...8,038,805
Ensembl chr 1:7,816,838...8,038,665
JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 multiple interactions
decreases activity
ISO ciprofibrate inhibits the reaction [AKR1B10 protein results in increased reduction of Daunorubicin]; ciprofibrate inhibits the reaction [AKR1B10 protein results in increased reduction of Glyceraldehyde]
ciprofibrate results in decreased activity of AKR1B10 protein; ciprofibrate results in decreased activity of AKR1B10 protein mutant form
CTD PMID:18325492, PMID:19028477 NCBI chr 4:61,813,265...61,830,371
Ensembl chr 4:61,771,970...61,828,657
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 increases expression ISO
EXP
ciprofibrate results in increased expression of ALDH1A1 mRNA CTD PMID:17998271, PMID:27225895 NCBI chr 1:238,222,689...238,264,381
Ensembl chr 1:238,222,521...238,264,330
JBrowse link
G Aldh3a2 aldehyde dehydrogenase 3 family, member A2 increases expression ISO ciprofibrate results in increased expression of ALDH3A2 mRNA CTD PMID:17998271 NCBI chr10:47,525,486...47,546,535
Ensembl chr10:47,525,493...47,546,345
JBrowse link
G Aldh9a1 aldehyde dehydrogenase 9 family, member A1 increases expression ISO ciprofibrate results in increased expression of ALDH9A1 mRNA CTD PMID:17998271 NCBI chr13:85,580,828...85,597,497
Ensembl chr13:85,580,828...85,597,493
JBrowse link
G Anxa2 annexin A2 increases expression ISO ciprofibrate results in increased expression of ANXA2 mRNA CTD PMID:12771043 NCBI chr 8:75,687,134...75,723,589
Ensembl chr 8:75,687,100...75,723,594
JBrowse link
G Apcs amyloid P component, serum increases expression ISO ciprofibrate results in increased expression of APCS mRNA CTD PMID:12771043 NCBI chr13:91,426,621...91,427,417
Ensembl chr13:91,426,479...91,427,575
JBrowse link
G Apoa1 apolipoprotein A1 decreases expression ISO ciprofibrate results in decreased expression of APOA1 mRNA CTD PMID:7983038 NCBI chr 8:50,525,091...50,526,875
Ensembl chr 8:50,525,091...50,526,875
JBrowse link
G Asgr1 asialoglycoprotein receptor 1 decreases expression EXP ciprofibrate results in decreased expression of ASGR1 protein CTD PMID:2404574 NCBI chr10:56,662,188...56,666,086
Ensembl chr10:56,662,242...56,666,086
JBrowse link
G Baat bile acid CoA:amino acid N-acyltransferase decreases expression ISO ciprofibrate results in decreased expression of BAAT mRNA CTD PMID:12771043 NCBI chr 5:64,768,397...64,777,368
Ensembl chr 5:64,768,401...64,777,368
JBrowse link
G Bdh1 3-hydroxybutyrate dehydrogenase 1 decreases activity
increases expression
EXP ciprofibrate results in decreased activity of BDH1 protein
ciprofibrate results in increased expression of BDH1 mRNA
CTD PMID:1777922 NCBI chr11:72,577,547...72,619,435
Ensembl chr11:72,578,533...72,614,176
JBrowse link
G C9 complement C9 decreases expression ISO ciprofibrate results in decreased expression of C9 mRNA CTD PMID:12771043 NCBI chr 2:55,775,562...55,823,807
Ensembl chr 2:55,775,274...55,823,826
JBrowse link
G Cat catalase multiple interactions
increases activity
increases expression
EXP [Dexamethasone co-treated with ciprofibrate] results in increased expression of CAT protein
ciprofibrate results in increased activity of CAT protein
ciprofibrate results in increased expression of CAT protein
CTD PMID:1740018, PMID:9736482, PMID:15965953 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cbr1 carbonyl reductase 1 increases expression ISO ciprofibrate results in increased expression of CBR1 mRNA CTD PMID:12771043 NCBI chr11:33,813,041...33,815,418
Ensembl chr11:33,845,463...33,847,793
JBrowse link
G Ccnd2 cyclin D2 decreases expression ISO ciprofibrate results in decreased expression of CCND2 mRNA; ciprofibrate results in decreased expression of CCND2 protein CTD PMID:12649303 NCBI chr 4:159,674,885...159,697,207
Ensembl chr 4:159,674,885...159,697,207
JBrowse link
G Cd14 CD14 molecule increases expression ISO ciprofibrate results in increased expression of CD14 protein CTD PMID:12649303 NCBI chr18:29,560,341...29,562,290
Ensembl chr18:29,560,365...29,562,153
JBrowse link
G Cd36 CD36 molecule increases expression ISO ciprofibrate results in increased expression of CD36 mRNA CTD PMID:12771043 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749
JBrowse link
G Cd63 Cd63 molecule increases expression ISO ciprofibrate results in increased expression of CD63 mRNA CTD PMID:12771043 NCBI chr 7:3,320,250...3,335,583
Ensembl chr 7:3,320,103...3,335,582
JBrowse link
G Col4a2 collagen type IV alpha 2 chain increases expression ISO ciprofibrate results in increased expression of COL4A2 mRNA CTD PMID:12771043 NCBI chr16:83,386,388...83,522,169
Ensembl chr16:83,387,364...83,438,561
JBrowse link
G Cpt1b carnitine palmitoyltransferase 1B increases expression EXP
ISO
ciprofibrate results in increased expression of CPT1B mRNA CTD PMID:27225895 NCBI chr 7:130,395,211...130,404,731
Ensembl chr 7:130,395,194...130,405,347
JBrowse link
G Cpt2 carnitine palmitoyltransferase 2 increases expression EXP
ISO
ciprofibrate results in increased expression of CPT2 mRNA CTD PMID:27225895 NCBI chr 5:127,505,646...127,523,016
Ensembl chr 5:127,505,614...127,523,089
JBrowse link
G Crat carnitine O-acetyltransferase increases expression ISO ciprofibrate results in increased expression of CRAT mRNA CTD PMID:12771043 NCBI chr 3:8,967,984...8,981,959
Ensembl chr 3:8,968,417...8,981,362
JBrowse link
G Ctsb cathepsin B increases expression ISO ciprofibrate results in increased expression of CTSB mRNA CTD PMID:12771043 NCBI chr15:46,316,741...46,337,613
Ensembl chr15:46,316,741...46,337,612
JBrowse link
G Ctsl cathepsin L increases expression ISO ciprofibrate results in increased expression of CTSL mRNA CTD PMID:12771043 NCBI chr17:1,873,105...1,879,266
Ensembl chr17:1,872,848...1,879,279
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 decreases expression ISO ciprofibrate results in decreased expression of CXCL12 mRNA CTD PMID:12771043 NCBI chr 4:149,261,044...149,273,891
Ensembl chr 4:149,261,044...149,273,891
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases expression
multiple interactions
EXP
ISO
ciprofibrate results in decreased expression of CYP1A2 mRNA
ciprofibrate inhibits the reaction [Phenobarbital results in increased expression of CYP1A2 mRNA]
CTD PMID:7676460, PMID:17962186 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 decreases expression ISO ciprofibrate results in decreased expression of CYP26A1 mRNA CTD PMID:12771043 NCBI chr 1:256,382,861...256,386,729
Ensembl chr 1:256,382,791...256,386,729
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 increases expression
decreases expression
multiple interactions
EXP
ISO
ciprofibrate results in increased expression of CYP2B1 mRNA
ciprofibrate results in decreased expression of CYP2B10 mRNA
ciprofibrate inhibits the reaction [1,4-bis(2-(3,5-dichloropyridyloxy))benzene promotes the reaction [NR1I3 protein binds to CYP2B10 promoter]]; ciprofibrate inhibits the reaction [Phenobarbital results in increased expression of CYP2B10 mRNA]
pyridine promotes the reaction [ciprofibrate results in increased expression of CYP2B1 protein]
CTD PMID:7587954, PMID:17962186, PMID:27225895 NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783
JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 increases expression
multiple interactions
EXP ciprofibrate results in increased expression of CYP2B2 mRNA
pyridine promotes the reaction [ciprofibrate results in increased expression of CYP2B2 protein]
CTD PMID:7587954 NCBI chr 1:83,103,925...83,119,578
Ensembl chr 1:83,103,925...83,119,193
JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 decreases expression ISO ciprofibrate results in decreased expression of CYP2C29 mRNA CTD PMID:12771043 NCBI chr 1:147,236,480...147,307,988 JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions
increases expression
EXP [Acetone co-treated with ciprofibrate] results in increased expression of CYP2E1 protein; [Thiazoles co-treated with ciprofibrate] results in increased expression of CYP2E1 protein; pyridine promotes the reaction [ciprofibrate results in increased expression of CYP2E1 protein]
ciprofibrate results in increased expression of CYP2E1 mRNA
CTD PMID:7587954 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 decreases expression EXP ciprofibrate results in decreased expression of CYP3A2 mRNA CTD PMID:7676460 NCBI chr12:11,641,500...11,677,818
Ensembl chr12:11,655,402...11,733,136
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 increases expression
multiple interactions
EXP ciprofibrate results in increased expression of CYP3A23-3A1 mRNA
INS protein affects the reaction [ciprofibrate results in increased expression of CYP3A23-3A1 mRNA]
CTD PMID:10215695 NCBI chr12:11,053,888...11,082,742
Ensembl chr12:11,655,402...11,733,136
JBrowse link
G Cyp4a1 cytochrome P450, family 4, subfamily a, polypeptide 1 increases activity
increases expression
EXP ciprofibrate results in increased activity of CYP4A1 protein
ciprofibrate results in increased expression of CYP4A1 mRNA; ciprofibrate results in increased expression of CYP4A1 protein
CTD PMID:2390105, PMID:7587954, PMID:7676460, PMID:19647067, PMID:27225895 NCBI chr 5:134,492,734...134,507,158
Ensembl chr 5:134,492,756...134,507,154
JBrowse link
G Cyp4f1 cytochrome P450, family 4, subfamily f, polypeptide 1 decreases expression ISO ciprofibrate results in decreased expression of CYP4F14 mRNA CTD PMID:12771043 NCBI chr 7:15,179,472...15,191,113
Ensembl chr 7:15,179,467...15,190,796
JBrowse link
G Cyp7b1 cytochrome P450 family 7 subfamily B member 1 decreases expression ISO ciprofibrate results in decreased expression of CYP7B1 mRNA CTD PMID:12771043 NCBI chr 2:102,701,903...102,871,257
Ensembl chr 2:102,701,903...102,871,257
JBrowse link
G Dpp4 dipeptidylpeptidase 4 decreases expression EXP ciprofibrate results in decreased expression of DPP4 protein CTD PMID:2404574 NCBI chr 3:48,291,055...48,372,672
Ensembl chr 3:48,291,055...48,372,672
JBrowse link
G Ech1 enoyl-CoA hydratase 1 increases expression EXP ciprofibrate results in increased expression of ECH1 protein CTD PMID:1740018 NCBI chr 1:87,009,798...87,015,996
Ensembl chr 1:87,009,730...87,016,005
JBrowse link
G Egfr epidermal growth factor receptor decreases expression EXP ciprofibrate results in decreased expression of EGFR protein CTD PMID:2404574 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
JBrowse link
G Ehhadh enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase increases expression ISO
EXP
ciprofibrate results in increased expression of EHHADH mRNA CTD PMID:2390105, PMID:12771043, PMID:27225895 NCBI chr11:82,945,104...82,978,364
Ensembl chr11:82,945,104...82,978,364
JBrowse link
G Elovl3 ELOVL fatty acid elongase 3 decreases expression ISO ciprofibrate results in decreased expression of ELOVL3 mRNA CTD PMID:12771043 NCBI chr 1:265,883,353...265,887,181
Ensembl chr 1:265,883,355...265,887,226
JBrowse link
G Ets2 ETS proto-oncogene 2, transcription factor increases expression ISO ciprofibrate results in increased expression of ETS2 mRNA CTD PMID:12771043 NCBI chr11:36,075,709...36,092,495
Ensembl chr11:36,075,709...36,092,495
JBrowse link
G Fabp1 fatty acid binding protein 1 increases expression EXP
ISO
ciprofibrate results in increased expression of FABP1 mRNA CTD PMID:27225895 NCBI chr 4:99,063,181...99,066,957
Ensembl chr 4:99,063,181...99,066,954
JBrowse link
G Fabp4 fatty acid binding protein 4 increases expression ISO ciprofibrate results in increased expression of FABP4 mRNA CTD PMID:12771043 NCBI chr 2:93,792,666...93,797,267
Ensembl chr 2:93,792,601...93,797,305
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression ISO ciprofibrate analog results in increased expression of FOS mRNA CTD PMID:8764118 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit decreases activity
decreases expression
EXP ciprofibrate results in decreased activity of GCLC protein
ciprofibrate results in decreased expression of GCLC mRNA
CTD PMID:7676460 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Gjb1 gap junction protein, beta 1 multiple interactions EXP [Diethylnitrosamine co-treated with ciprofibrate] results in decreased expression of GJB1 protein; [Ethylnitrosourea co-treated with ciprofibrate] results in decreased expression of GJB1 protein CTD PMID:1973356 NCBI chr  X:71,272,030...71,279,973
Ensembl chr  X:71,272,042...71,279,977
JBrowse link
G Gpx1 glutathione peroxidase 1 decreases activity EXP ciprofibrate results in decreased activity of GPX1 protein CTD PMID:19544052 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G Gsta1 glutathione S-transferase alpha 1 decreases expression EXP ciprofibrate results in decreased expression of GSTA1 mRNA CTD PMID:7676460 NCBI chr 9:27,366,404...27,381,004
Ensembl chr 9:27,368,272...27,452,902
JBrowse link
G Gsta2 glutathione S-transferase alpha 2 decreases expression EXP ciprofibrate results in decreased expression of GSTA2 mRNA; ciprofibrate results in decreased expression of GSTA3 mRNA CTD PMID:7676460 NCBI chr 8:85,640,081...85,645,621 JBrowse link
G Gstk1 glutathione S-transferase kappa 1 increases expression ISO ciprofibrate results in increased expression of GSTK1 mRNA CTD PMID:18723825 NCBI chr 4:71,621,777...71,626,096
Ensembl chr 4:71,621,729...71,626,107
JBrowse link
G Gstm1 glutathione S-transferase mu 1 decreases expression EXP ciprofibrate results in decreased expression of GSTM1 mRNA CTD PMID:7676460 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G Hadhb hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta increases expression EXP ciprofibrate results in increased expression of HADHB mRNA CTD PMID:27225895 NCBI chr 6:27,555,408...27,589,539
Ensembl chr 6:27,555,412...27,582,995
JBrowse link
G Hdac1 histone deacetylase 1 increases expression ISO ciprofibrate results in increased expression of HDAC1 mRNA CTD PMID:12771043 NCBI chr 5:147,716,664...147,743,723
Ensembl chr 5:147,716,664...147,743,723
JBrowse link
G Hgf hepatocyte growth factor increases expression EXP ciprofibrate results in increased expression of HGF protein CTD PMID:1370768 NCBI chr 4:15,435,460...15,505,377
Ensembl chr 4:15,433,295...15,505,362
JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 increases expression ISO ciprofibrate results in increased expression of HMGCS2 mRNA CTD PMID:12381268 NCBI chr 2:200,452,623...200,480,785
Ensembl chr 2:200,452,624...200,479,423
JBrowse link
G Hsd17b11 hydroxysteroid (17-beta) dehydrogenase 11 increases expression ISO ciprofibrate results in increased expression of HSD17B11 mRNA CTD PMID:12771043 NCBI chr14:7,054,724...7,104,567
Ensembl chr14:7,073,445...7,104,566
JBrowse link
G Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 increases expression EXP ciprofibrate results in increased expression of HSD17B4 mRNA CTD PMID:9209713 NCBI chr18:44,810,462...44,897,677
Ensembl chr18:44,810,388...44,897,640
JBrowse link
G Hsd3b3 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3 decreases expression ISO ciprofibrate results in decreased expression of HSD3B3 mRNA CTD PMID:12771043 NCBI chr 2:200,756,557...200,762,492
Ensembl chr 2:200,585,748...200,762,492
JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 increases expression ISO ciprofibrate results in increased expression of IGFBP1 mRNA CTD PMID:12771043 NCBI chr14:87,448,716...87,453,783
Ensembl chr14:87,448,692...87,453,785
JBrowse link
G Igfbp2 insulin-like growth factor binding protein 2 increases expression ISO ciprofibrate results in increased expression of IGFBP2 mRNA CTD PMID:12771043 NCBI chr 9:80,118,029...80,144,804
Ensembl chr 9:80,118,029...80,144,789
JBrowse link
G Il12b interleukin 12B multiple interactions ISO ciprofibrate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein] CTD PMID:15968640 NCBI chr10:30,034,447...30,048,774
Ensembl chr10:30,038,709...30,048,085
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO ciprofibrate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein] CTD PMID:15968640 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il1rap interleukin 1 receptor accessory protein decreases expression ISO ciprofibrate results in decreased expression of IL1RAP mRNA CTD PMID:12771043 NCBI chr11:77,456,648...77,593,208
Ensembl chr11:77,463,954...77,593,207
JBrowse link
G Impact impact RWD domain protein increases expression ISO ciprofibrate results in increased expression of IMPACT mRNA CTD PMID:12771043 NCBI chr18:4,325,872...4,346,734
Ensembl chr18:4,325,875...4,346,769
JBrowse link
G Ins2 insulin 2 multiple interactions EXP INS protein affects the reaction [ciprofibrate results in increased expression of CYP3A23-3A1 mRNA] CTD PMID:10215695 NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034
JBrowse link
G Itln1 intelectin 1 increases expression ISO ciprofibrate results in increased expression of ITLN1 mRNA CTD PMID:12771043 NCBI chr13:89,919,570...89,929,774
Ensembl chr13:89,919,667...89,929,770
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases expression ISO ciprofibrate analog results in increased expression of JUN mRNA CTD PMID:8764118 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
ISO 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [ciprofibrate analog results in increased expression of JUNB mRNA] CTD PMID:8764118 NCBI chr19:26,092,972...26,094,756
Ensembl chr19:26,092,974...26,094,756
JBrowse link
G Krt8 keratin 8 increases expression ISO ciprofibrate results in increased expression of KRT8 mRNA CTD PMID:12771043 NCBI chr 7:143,596,511...143,603,745
Ensembl chr 7:143,596,511...143,603,803
JBrowse link
G Lcn2 lipocalin 2 increases expression ISO ciprofibrate results in increased expression of LCN2 mRNA CTD PMID:12771043 NCBI chr 3:11,414,189...11,417,534
Ensembl chr 3:11,414,186...11,417,546
JBrowse link
G Lgals3bp galectin 3 binding protein increases expression ISO ciprofibrate results in increased expression of LGALS3BP mRNA CTD PMID:12771043 NCBI chr10:107,415,334...107,424,672
Ensembl chr10:107,415,326...107,424,710
JBrowse link
G Lpcat3 lysophosphatidylcholine acyltransferase 3 increases expression ISO ciprofibrate results in increased expression of LPCAT3 mRNA CTD PMID:12771043 NCBI chr 4:157,181,722...157,222,997
Ensembl chr 4:157,181,795...157,222,996
JBrowse link
G Lpl lipoprotein lipase increases expression
increases activity
ISO ciprofibrate results in increased expression of LPL mRNA
ciprofibrate results in increased activity of LPL protein
CTD PMID:8593127, PMID:12771043 NCBI chr16:22,537,687...22,561,487
Ensembl chr16:22,537,056...22,561,496
JBrowse link
G Ly6d lymphocyte antigen 6 family member D increases expression ISO ciprofibrate results in increased expression of LY6D mRNA CTD PMID:12771043 NCBI chr 7:115,993,304...115,994,812
Ensembl chr 7:115,993,301...115,994,783
JBrowse link
G Mgst1 microsomal glutathione S-transferase 1 increases expression ISO ciprofibrate results in increased expression of MGST1 mRNA CTD PMID:18723825 NCBI chr 4:172,119,382...172,134,609
Ensembl chr 4:172,119,331...172,134,607
JBrowse link
G Myb MYB proto-oncogene, transcription factor decreases expression ISO ciprofibrate results in decreased expression of MYB mRNA; ciprofibrate results in decreased expression of MYB protein CTD PMID:12649303 NCBI chr 1:16,658,178...16,690,135
Ensembl chr 1:16,659,442...16,687,817
JBrowse link
G Myh1 myosin heavy chain 1 decreases expression ISO ciprofibrate results in decreased expression of MYH1 mRNA CTD PMID:12771043 NCBI chr10:53,740,841...53,764,610
Ensembl chr10:53,713,938...53,848,347
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 increases activity ISO ciprofibrate results in increased activity of NFE2L2 protein CTD PMID:30114225, PMID:30203046 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 increases response to substance ISO NFKB1 results in increased susceptibility to ciprofibrate CTD PMID:16434500 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression EXP ciprofibrate results in increased expression of NQO1 mRNA CTD PMID:7676460 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 decreases expression ISO ciprofibrate results in decreased expression of NR1H3 mRNA CTD PMID:12771043 NCBI chr 3:80,004,130...80,014,197
Ensembl chr 3:80,004,130...80,012,750
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 affects localization
increases activity
increases expression
multiple interactions
ISO
EXP
ciprofibrate affects the localization of NR1I3 protein
ciprofibrate results in increased activity of NR1I3 protein
ciprofibrate results in increased expression of NR1I3 mRNA
ciprofibrate results in increased expression of NR1I3 mRNA; ciprofibrate results in increased expression of NR1I3 protein
ciprofibrate inhibits the reaction [1,4-bis(2-(3,5-dichloropyridyloxy))benzene promotes the reaction [NR1I3 protein binds to CYP2B10 promoter]]
CTD PMID:17962186, PMID:20208394, PMID:25949234, PMID:30203046 NCBI chr13:89,585,072...89,591,278
Ensembl chr13:89,586,283...89,591,277
JBrowse link
G Oat ornithine aminotransferase decreases expression ISO ciprofibrate results in decreased expression of OAT mRNA CTD PMID:12771043 NCBI chr 1:204,562,289...204,582,070
Ensembl chr 1:204,562,289...204,582,070
JBrowse link
G Pah phenylalanine hydroxylase decreases expression ISO ciprofibrate results in decreased expression of PAH mRNA CTD PMID:12771043 NCBI chr 7:28,066,639...28,129,772
Ensembl chr 7:28,066,635...28,129,769
JBrowse link
G Palmd palmdelphin increases expression ISO ciprofibrate results in increased expression of PALMD mRNA CTD PMID:12771043 NCBI chr 2:220,481,292...220,536,004
Ensembl chr 2:220,481,616...220,535,751
JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 increases expression ISO
EXP
ciprofibrate results in increased expression of PDK4 mRNA CTD PMID:12771043, PMID:27225895 NCBI chr 4:30,546,772...30,556,774
Ensembl chr 4:30,546,664...30,556,814
JBrowse link
G Pex11a peroxisomal biogenesis factor 11 alpha increases expression ISO ciprofibrate results in increased expression of PEX11A mRNA CTD PMID:12771043 NCBI chr 1:141,474,189...141,481,270
Ensembl chr 1:141,474,180...141,481,315
JBrowse link
G Phlda1 pleckstrin homology-like domain, family A, member 1 decreases expression ISO ciprofibrate results in decreased expression of PHLDA1 mRNA CTD PMID:12771043 NCBI chr 7:54,247,460...54,249,664
Ensembl chr 7:54,247,460...54,249,664
JBrowse link
G Plin2 perilipin 2 increases expression ISO ciprofibrate results in increased expression of PLIN2 mRNA CTD PMID:12771043, PMID:23737761 NCBI chr 5:104,984,413...105,010,863
Ensembl chr 5:104,984,414...105,010,857
JBrowse link
G Plscr1 phospholipid scramblase 1 increases expression ISO ciprofibrate results in increased expression of PLSCR1 mRNA CTD PMID:12771043 NCBI chr 8:99,625,523...99,645,882
Ensembl chr 8:99,625,545...99,725,217
JBrowse link
G Pon1 paraoxonase 1 decreases expression ISO ciprofibrate results in decreased expression of PON1 mRNA CTD PMID:22653878 NCBI chr 4:30,249,749...30,276,297
Ensembl chr 4:30,249,742...30,276,372
JBrowse link
G Pon2 paraoxonase 2 decreases expression ISO ciprofibrate results in decreased expression of PON2 mRNA CTD PMID:22653878 NCBI chr 4:30,344,705...30,380,119
Ensembl chr 4:30,344,709...30,380,119
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions
increases activity
increases expression
affects response to substance
ISO
EXP
ciprofibrate binds to and results in increased activity of PPARA protein
ciprofibrate results in increased activity of PPARA protein
ciprofibrate results in increased expression of PPARA mRNA
PPARA protein affects the susceptibility to ciprofibrate
[ciprofibrate binds to PPARA protein] which results in increased expression of ABCC3 mRNA; ciprofibrate binds to and results in increased activity of PPARA protein
CTD PMID:9688458, PMID:15833929, PMID:15853379, PMID:15919853, PMID:15968640, PMID:16680075, PMID:16731579, PMID:17627975, PMID:18375545, PMID:25689681, PMID:30203046 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression ISO ciprofibrate analog results in increased expression of PTGS2 mRNA; ciprofibrate analog results in increased expression of PTGS2 protein CTD PMID:9013627 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Rbm3 RNA binding motif protein 3 increases expression ISO ciprofibrate results in increased expression of RBM3 mRNA CTD PMID:12771043 NCBI chr  X:15,098,880...15,102,344
Ensembl chr  X:15,098,904...15,102,340
JBrowse link
G Retsat retinol saturase increases expression ISO
EXP
ciprofibrate results in increased expression of RETSAT mRNA CTD PMID:27225895 NCBI chr 4:100,465,365...100,474,128
Ensembl chr 4:100,465,170...100,474,301
JBrowse link
G Rpl12 ribosomal protein L12 increases expression ISO ciprofibrate results in increased expression of RPL12 mRNA CTD PMID:12771043 NCBI chr 3:12,009,578...12,011,952
Ensembl chr 3:12,009,578...12,011,666
JBrowse link
G Scd stearoyl-CoA desaturase multiple interactions ISO ciprofibrate promotes the reaction [Fatty Acids, Unsaturated deficiency results in increased expression of SCD1 mRNA]; ciprofibrate results in increased expression of and results in increased degradation of SCD1 mRNA; Dactinomycin inhibits the reaction [ciprofibrate results in increased expression of SCD1 mRNA] CTD PMID:11172741 NCBI chr 1:264,159,966...264,173,061
Ensembl chr 1:264,160,129...264,172,729
JBrowse link
G Slc10a1 solute carrier family 10 member 1 decreases expression ISO ciprofibrate results in decreased expression of SLC10A1 protein CTD PMID:12381268 NCBI chr 6:104,617,730...104,631,355
Ensembl chr 6:104,617,730...104,631,355
JBrowse link
G Slc16a1 solute carrier family 16 member 1 increases expression ISO ciprofibrate results in increased expression of SLC16A1 mRNA CTD PMID:12771043 NCBI chr 2:207,108,552...207,129,352
Ensembl chr 2:207,108,552...207,128,554
JBrowse link
G Slc25a20 solute carrier family 25 member 20 increases expression EXP ciprofibrate results in increased expression of SLC25A20 mRNA CTD PMID:27225895 NCBI chr 8:117,455,308...117,476,762
Ensembl chr 8:117,455,262...117,476,734
JBrowse link
G Slc25a34 solute carrier family 25, member 34 increases expression ISO
EXP
ciprofibrate results in increased expression of SLC25A34 mRNA CTD PMID:27225895 NCBI chr 5:160,175,206...160,179,978
Ensembl chr 5:160,176,124...160,179,978
JBrowse link
G Slc37a4 solute carrier family 37 member 4 decreases expression ISO ciprofibrate results in decreased expression of SLC37A4 mRNA CTD PMID:12771043 NCBI chr 8:48,716,914...48,723,024
Ensembl chr 8:48,716,939...48,723,024
JBrowse link
G Slc4a4 solute carrier family 4 member 4 increases expression ISO ciprofibrate results in increased expression of SLC4A4 mRNA CTD PMID:12771043 NCBI chr14:20,476,258...20,817,042
Ensembl chr14:20,479,323...20,920,286
JBrowse link
G Slco1b2 solute carrier organic anion transporter family member 1B2 decreases expression ISO ciprofibrate results in decreased expression of SLCO1B2 mRNA CTD PMID:15919853 NCBI chr 4:175,814,118...175,881,775
Ensembl chr 4:175,814,118...175,881,768
JBrowse link
G Slco2a1 solute carrier organic anion transporter family, member 2a1 decreases expression ISO ciprofibrate results in decreased expression of SLCO2A1 mRNA CTD PMID:15919853 NCBI chr 8:111,495,443...111,577,320
Ensembl chr 8:111,495,331...111,577,833
JBrowse link
G Slco2b1 solute carrier organic anion transporter family, member 2b1 decreases expression ISO ciprofibrate results in decreased expression of SLCO2B1 mRNA CTD PMID:15919853 NCBI chr 1:164,623,313...164,671,612
Ensembl chr 1:164,623,599...164,671,577
JBrowse link
G Sod1 superoxide dismutase 1 increases expression
increases activity
EXP ciprofibrate results in increased expression of SOD1 mRNA
ciprofibrate results in increased activity of SOD1 protein
CTD PMID:7676460, PMID:19544052 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Sod2 superoxide dismutase 2 decreases activity EXP ciprofibrate results in decreased activity of SOD2 protein CTD PMID:19544052 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Sqstm1 sequestosome 1 increases expression ISO ciprofibrate results in increased expression of SQSTM1 mRNA CTD PMID:12771043 NCBI chr10:35,704,728...35,716,316
Ensembl chr10:35,704,730...35,716,294
JBrowse link
G Stat5b signal transducer and activator of transcription 5B decreases activity ISO ciprofibrate results in decreased activity of STAT5B protein CTD PMID:30114225 NCBI chr10:88,686,207...88,712,313
Ensembl chr10:88,686,207...88,754,829
JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 multiple interactions
increases expression
ISO ciprofibrate results in increased expression of and results in increased activity of SULT2A1 protein
ciprofibrate results in increased expression of SULT2A1 mRNA
CTD PMID:15635043 NCBI chr 1:76,558,721...76,614,315
Ensembl chr 1:76,252,329...76,780,230
JBrowse link
G Tagln2 transgelin 2 increases expression ISO ciprofibrate results in increased expression of TAGLN2 mRNA CTD PMID:12771043 NCBI chr13:90,807,196...90,814,119
Ensembl chr13:90,807,199...90,814,119
JBrowse link
G Tm4sf4 transmembrane 4 L six family member 4 increases expression ISO ciprofibrate results in increased expression of TM4SF4 mRNA CTD PMID:12771043 NCBI chr 2:147,532,032...147,547,254
Ensembl chr 2:147,496,229...147,547,252
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO ciprofibrate inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein] CTD PMID:15968640 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Trpv2 transient receptor potential cation channel, subfamily V, member 2 decreases expression ISO ciprofibrate results in decreased expression of TRPV2 mRNA CTD PMID:12771043 NCBI chr10:48,903,540...48,925,036
Ensembl chr10:48,903,540...48,925,030
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases expression ISO ciprofibrate results in increased expression of UGT1A1 mRNA CTD PMID:19144771 NCBI chr 9:95,295,701...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 increases expression ISO ciprofibrate results in increased expression of UGT1A6 mRNA CTD PMID:19144771 NCBI chr 9:95,241,609...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 increases expression ISO ciprofibrate results in increased expression of UGT1A9 mRNA CTD PMID:19144771 NCBI chr 9:95,161,157...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt2b17 UDP glucuronosyltransferase family 2 member B17 increases glucuronidation EXP UGT2B1 protein results in increased glucuronidation of ciprofibrate CTD PMID:8302279 NCBI chr14:22,724,399...22,736,148
Ensembl chr14:22,724,070...22,825,444
JBrowse link
G Vnn3 vanin 3 increases expression ISO ciprofibrate results in increased expression of VNN3 mRNA CTD PMID:12771043 NCBI chr 1:22,649,114...22,661,376
Ensembl chr 1:22,649,081...22,661,377
JBrowse link
cycloprothrin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Esr1 estrogen receptor 1 decreases activity EXP cycloprothrin results in decreased activity of ESR1 protein CTD PMID:20410157 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Gstp1 glutathione S-transferase pi 1 affects binding ISO cycloprothrin binds to GSTP1 protein CTD PMID:32278787 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Mmp9 matrix metallopeptidase 9 affects binding ISO cycloprothrin binds to MMP9 protein CTD PMID:32278787 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Rora RAR-related orphan receptor A affects binding ISO cycloprothrin binds to RORA protein CTD PMID:32278787 NCBI chr 8:75,515,886...75,616,477
Ensembl chr 8:75,516,904...75,607,212
JBrowse link
G Rorc RAR-related orphan receptor C affects binding ISO cycloprothrin binds to RORC protein CTD PMID:32278787 NCBI chr 2:195,612,471...195,636,797
Ensembl chr 2:195,617,021...195,637,630
JBrowse link
cyfluthrin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase decreases activity EXP cyfluthrin results in decreased activity of ACHE protein CTD PMID:26604153 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
JBrowse link
G Ar androgen receptor decreases activity
multiple interactions
ISO cyfluthrin results in decreased activity of AR protein
Dihydrotestosterone inhibits the reaction [cyfluthrin results in increased activity of AR protein]
CTD PMID:15064155, PMID:20410157 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO cyfluthrin results in increased expression of BAX mRNA CTD PMID:32028016 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcr BCR activator of RhoGEF and GTPase increases expression ISO cyfluthrin results in increased expression of BCR protein CTD PMID:16790487 NCBI chr20:14,421,250...14,546,406
Ensembl chr20:14,421,141...14,545,772
JBrowse link
G Bdnf brain-derived neurotrophic factor increases expression EXP cyfluthrin results in increased expression of BDNF mRNA CTD PMID:16166269 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha increases expression ISO cyfluthrin results in increased expression of CAMK2A mRNA CTD PMID:32028016 NCBI chr18:56,193,978...56,295,869
Ensembl chr18:56,193,978...56,295,869
JBrowse link
G Camk2b calcium/calmodulin-dependent protein kinase II beta increases expression ISO cyfluthrin results in increased expression of CAMK2B mRNA CTD PMID:32028016 NCBI chr14:86,208,876...86,297,727
Ensembl chr14:86,208,901...86,297,652
JBrowse link
G Cat catalase decreases activity
affects binding
decreases expression
multiple interactions
ISO
EXP
cyfluthrin results in decreased activity of CAT protein
cyfluthrin binds to CAT protein
cyfluthrin results in decreased expression of CAT protein
Selenium inhibits the reaction [cyfluthrin results in decreased activity of CAT protein]
[Melatonin co-treated with cyfluthrin] results in increased activity of CAT protein; Melatonin inhibits the reaction [cyfluthrin results in decreased activity of CAT protein]; N-acetylserotonin inhibits the reaction [cyfluthrin results in decreased activity of CAT protein]
CTD PMID:19961921, PMID:23595963, PMID:26604153, PMID:32278787 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Ces2h carboxylesterase 2H increases metabolic processing ISO CES2 protein results in increased metabolism of cyfluthrin CTD PMID:19249324 NCBI chr19:37,052,555...37,067,176
Ensembl chr19:37,052,556...37,067,156
JBrowse link
G Chat choline O-acetyltransferase decreases expression EXP cyfluthrin results in decreased expression of CHAT protein CTD PMID:26604153 NCBI chr16:8,576,858...8,686,131
Ensembl chr16:8,577,840...8,686,131
JBrowse link
G Clip3 CAP-GLY domain containing linker protein 3 increases expression ISO cyfluthrin results in increased expression of CLIP3 protein CTD PMID:16790487 NCBI chr 1:88,750,453...88,766,453
Ensembl chr 1:90,962,707...90,978,907
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases activity EXP cyfluthrin results in increased activity of CYP2E1 protein CTD PMID:23639246 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Esr1 estrogen receptor 1 increases activity
decreases activity
ISO
EXP
cyfluthrin results in increased activity of ESR1 protein
cyfluthrin results in decreased activity of ESR1 protein
CTD PMID:15064155, PMID:20410157 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Gap43 growth associated protein 43 increases expression ISO cyfluthrin results in increased expression of GAP43 mRNA CTD PMID:32028016 NCBI chr11:58,624,198...58,717,916
Ensembl chr11:58,624,198...58,717,914
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions
decreases activity
EXP Selenium inhibits the reaction [cyfluthrin results in decreased activity of GSR protein] CTD PMID:23595963 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Hydin Hydin, axonemal central pair apparatus protein decreases expression ISO cyfluthrin results in decreased expression of HYDIN protein CTD PMID:16790487 NCBI chr19:41,036,507...41,379,634
Ensembl chr19:41,036,510...41,379,588
JBrowse link
G Ifng interferon gamma multiple interactions ISO cyfluthrin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IFNG protein] CTD PMID:12755381 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Il4 interleukin 4 multiple interactions ISO cyfluthrin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL4 protein] CTD PMID:12755381 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Il6 interleukin 6 increases expression ISO cyfluthrin results in increased expression of IL6 protein CTD PMID:16790487 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases expression ISO cyfluthrin results in increased expression of MAPK1 protein CTD PMID:16790487 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases expression ISO cyfluthrin results in increased expression of MAPK3 protein CTD PMID:16790487 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Nefh neurofilament heavy increases expression ISO cyfluthrin results in increased expression of NEFH mRNA CTD PMID:32028016 NCBI chr14:85,181,572...85,191,557
Ensembl chr14:85,181,572...85,191,557
JBrowse link
G Nefl neurofilament light decreases expression ISO cyfluthrin results in decreased expression of NEFL mRNA CTD PMID:32028016 NCBI chr15:44,799,378...44,803,251
Ensembl chr15:44,799,334...44,804,574
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions ISO cyfluthrin inhibits the reaction [pregna-4,17-diene-3,16-dione results in decreased activity of NR1H4 protein] CTD PMID:25257666 NCBI chr 7:30,003,429...30,162,095
Ensembl chr 7:30,003,429...30,162,056
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity
multiple interactions
EXP
ISO
cyfluthrin results in increased activity of NR1I2 protein
cyfluthrin results in increased activity of NR1I2 protein; cyfluthrin results in increased activity of NR1I2 protein polymorphism
cyfluthrin binds to and results in increased activity of NR1I2 protein
CTD PMID:19249324, PMID:21115097, PMID:22206814 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Pgr progesterone receptor affects binding ISO cyfluthrin binds to PGR protein CTD PMID:32278787 NCBI chr 8:7,128,656...7,187,796
Ensembl chr 8:7,128,656...7,187,796
JBrowse link
G Pik3c3 phosphatidylinositol 3-kinase, catalytic subunit type 3 increases expression ISO cyfluthrin results in increased expression of PIK3C3 mRNA CTD PMID:32028016 NCBI chr18:22,964,121...23,047,896
Ensembl chr18:22,964,210...23,047,895
JBrowse link
G Ppp2r3b protein phosphatase 2, regulatory subunit B'', beta increases expression ISO cyfluthrin results in increased expression of PPP2R3B protein CTD PMID:16790487 NCBI chr14:1,469,748...1,476,353
Ensembl chr14:1,469,748...1,476,355
JBrowse link
G Scn10a sodium voltage-gated channel alpha subunit 10 multiple interactions
affects activity
EXP cyfluthrin affects the reaction [SCN10A protein results in increased transport of Sodium]
cyfluthrin affects the activity of SCN10A protein
CTD PMID:16051293, PMID:19766671 NCBI chr 8:128,298,593...128,416,896
Ensembl chr 8:128,298,594...128,416,650
JBrowse link
G Scn1b sodium voltage-gated channel beta subunit 1 multiple interactions EXP cyfluthrin affects the reaction [[SCN2A protein binds to SCN1B protein] which results in increased transport of Sodium] CTD PMID:18538810 NCBI chr 1:89,550,738...89,560,469
Ensembl chr 1:89,550,738...89,560,719
JBrowse link
G Scn2a sodium voltage-gated channel alpha subunit 2 multiple interactions EXP cyfluthrin affects the reaction [[SCN2A protein binds to SCN1B protein] which results in increased transport of Sodium] CTD PMID:18538810 NCBI chr 3:51,687,910...51,822,008
Ensembl chr 3:51,687,809...51,822,250
JBrowse link
G Scn3a sodium voltage-gated channel alpha subunit 3 multiple interactions EXP cyfluthrin affects the reaction [[SCN3A protein binds to SCN3B protein] which results in increased transport of Sodium] CTD PMID:18538810 NCBI chr 3:51,530,897...51,643,140
Ensembl chr 3:51,532,627...51,643,140
JBrowse link
G Scn3b sodium voltage-gated channel beta subunit 3 multiple interactions EXP cyfluthrin affects the reaction [[SCN3A protein binds to SCN3B protein] which results in increased transport of Sodium] CTD PMID:18538810 NCBI chr 8:44,136,413...44,159,011
Ensembl chr 8:44,136,496...44,159,010
JBrowse link
G Slc6a14 solute carrier family 6 member 14 decreases expression ISO cyfluthrin results in decreased expression of SLC6A14 protein CTD PMID:16790487 NCBI chr  X:120,624,522...120,647,964
Ensembl chr  X:120,624,518...120,649,111
JBrowse link
G Stat6 signal transducer and activator of transcription 6 decreases expression ISO cyfluthrin results in decreased expression of STAT6 protein CTD PMID:12755381 NCBI chr 7:70,946,228...70,963,542
Ensembl chr 7:70,946,228...70,964,484
JBrowse link
G Syn1 synapsin I decreases expression ISO cyfluthrin results in decreased expression of SYN1 mRNA CTD PMID:32028016 NCBI chr  X:1,321,315...1,379,202
Ensembl chr  X:1,321,315...1,379,198
JBrowse link
G Wnt3a Wnt family member 3A increases expression ISO cyfluthrin results in increased expression of WNT3A mRNA CTD PMID:32028016 NCBI chr10:45,598,898...45,643,151
Ensembl chr10:45,598,912...45,638,035
JBrowse link
G Wnt5a Wnt family member 5A increases expression ISO cyfluthrin results in increased expression of WNT5A mRNA CTD PMID:32028016 NCBI chr16:4,469,451...4,490,271
Ensembl chr16:4,469,468...4,489,860
JBrowse link
G Wnt7a Wnt family member 7A increases expression ISO cyfluthrin results in increased expression of WNT7A mRNA CTD PMID:32028016 NCBI chr 4:122,994,425...123,040,609
Ensembl chr 4:122,994,425...123,040,609
JBrowse link
cyhalothrin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adh4 alcohol dehydrogenase 4 (class II), pi polypeptide increases expression EXP cyhalothrin results in increased expression of ADH4 mRNA CTD PMID:29727961 NCBI chr 2:243,702,035...243,720,063
Ensembl chr 2:243,700,784...243,740,899
JBrowse link
G Adh6 alcohol dehydrogenase 6 (class V) increases expression EXP cyhalothrin results in increased expression of ADH6 mRNA CTD PMID:29727961 NCBI chr 2:243,656,568...243,687,857
Ensembl chr 2:243,550,627...243,687,857
JBrowse link
G Akt1 AKT serine/threonine kinase 1 increases activity ISO cyhalothrin results in increased activity of AKT1 CTD PMID:26969072 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 increases expression EXP cyhalothrin results in increased expression of ALDH1A1 mRNA CTD PMID:29727961 NCBI chr 1:238,222,689...238,264,381
Ensembl chr 1:238,222,521...238,264,330
JBrowse link
G Aldh1b1 aldehyde dehydrogenase 1 family, member B1 decreases expression EXP cyhalothrin results in decreased expression of ALDH1B1 mRNA CTD PMID:29727961 NCBI chr 5:61,382,351...61,387,359
Ensembl chr 5:61,382,351...61,387,358
JBrowse link
G Aldh3b1 aldehyde dehydrogenase 3 family, member B1 increases expression EXP cyhalothrin results in increased expression of ALDH3B1 mRNA CTD PMID:29727961 NCBI chr 1:219,145,457...219,181,536
Ensembl chr 1:219,145,459...219,186,860
JBrowse link
G Ar androgen receptor decreases activity
multiple interactions
ISO cyhalothrin results in decreased activity of AR protein
cyhalothrin inhibits the reaction [Dihydrotestosterone results in increased expression of AR mRNA]
CTD PMID:20410157, PMID:21310686 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression EXP cyhalothrin results in increased expression of BAX mRNA; cyhalothrin results in increased expression of BAX protein CTD PMID:29727961, PMID:30029170 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression EXP cyhalothrin results in decreased expression of BCL2 protein CTD PMID:30029170 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha decreases expression
multiple interactions
EXP cyhalothrin results in decreased expression of CAMK2A protein
cyhalothrin promotes the reaction [NGF protein results in increased expression of CAMK2A mRNA]
CTD PMID:28385489, PMID:28487251 NCBI chr18:56,193,978...56,295,869
Ensembl chr18:56,193,978...56,295,869
JBrowse link
G Camk2b calcium/calmodulin-dependent protein kinase II beta multiple interactions EXP cyhalothrin promotes the reaction [NGF protein results in increased expression of CAMK2B mRNA] CTD PMID:28385489 NCBI chr14:86,208,876...86,297,727
Ensembl chr14:86,208,901...86,297,652
JBrowse link
G Casp3 caspase 3 increases expression EXP cyhalothrin results in increased expression of CASP3 mRNA CTD PMID:29727961 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Cat catalase multiple interactions
decreases activity
EXP thymoquinone inhibits the reaction [cyhalothrin results in decreased activity of CAT protein] CTD PMID:26645134, PMID:27348886, PMID:28058584 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression EXP cyhalothrin results in increased expression of CCL2 protein CTD PMID:27348886 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccnd1 cyclin D1 affects expression
multiple interactions
ISO cyhalothrin affects the expression of CCND1 mRNA
fulvestrant inhibits the reaction [cyhalothrin affects the expression of CCND1 mRNA]
CTD PMID:26877835 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Cdk5 cyclin-dependent kinase 5 increases expression EXP cyhalothrin results in increased expression of CDK5 protein CTD PMID:28487251 NCBI chr 4:7,282,945...7,287,427
Ensembl chr 4:7,282,948...7,288,383
JBrowse link
G Ces1d carboxylesterase 1D multiple interactions
increases metabolic processing
ISO CES1 protein inhibits the reaction [cyhalothrin results in increased activity of NR1I2 protein]
CES1 protein results in increased metabolism of cyhalothrin
CTD PMID:19249324 NCBI chr19:15,195,514...15,239,827
Ensembl chr19:15,033,108...15,239,821
JBrowse link
G Creb1 cAMP responsive element binding protein 1 decreases phosphorylation
decreases expression
EXP cyhalothrin results in decreased phosphorylation of CREB1 protein
cyhalothrin results in decreased expression of CREB1 protein modified form
CTD PMID:28487251, PMID:28495607 NCBI chr 9:71,229,753...71,298,994
Ensembl chr 9:71,230,108...71,293,435
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 decreases expression EXP cyhalothrin results in decreased expression of CYP11A1 protein CTD PMID:30029170 NCBI chr 8:62,798,317...62,809,848
Ensembl chr 8:62,779,875...62,809,893
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression
increases activity
EXP cyhalothrin results in increased expression of CYP1A1 mRNA
cyhalothrin results in increased activity of CYP1A1 protein
CTD PMID:29727961 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases activity
increases expression
ISO
EXP
cyhalothrin results in increased activity of CYP1A2 protein
cyhalothrin results in increased expression of CYP1A2 mRNA
CTD PMID:22310298, PMID:29727961 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 decreases expression EXP cyhalothrin results in decreased expression of CYP26B1 mRNA CTD PMID:29727961 NCBI chr 4:116,261,796...116,278,615
Ensembl chr 4:116,261,796...116,278,615
JBrowse link
G Cyp2a1 cytochrome P450, family 2, subfamily a, polypeptide 1 increases activity
increases expression
EXP cyhalothrin results in increased activity of CYP2A1 protein
cyhalothrin results in increased expression of CYP2A1 mRNA
CTD PMID:29727961 NCBI chr 1:83,711,223...83,725,222
Ensembl chr 1:83,653,234...83,766,484
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 increases activity
increases expression
EXP cyhalothrin results in increased activity of CYP2B1 protein
cyhalothrin results in increased expression of CYP2B1 mRNA
CTD PMID:29727961 NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783
JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 increases expression EXP cyhalothrin results in increased expression of CYP2B2 mRNA CTD PMID:29727961 NCBI chr 1:83,103,925...83,119,578
Ensembl chr 1:83,103,925...83,119,193
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases activity
decreases activity
multiple interactions
increases expression
ISO cyhalothrin results in increased activity of CYP2B6 protein
cyhalothrin results in decreased activity of CYP2B6 protein
cyhalothrin inhibits the reaction [CYP2B6 protein results in increased hydroxylation of Bupropion]
cyhalothrin results in increased expression of CYP2B6 mRNA
CTD PMID:22310298, PMID:22634058 NCBI chr 1:83,163,103...83,236,615
Ensembl chr 1:83,163,079...83,236,615
JBrowse link
G Cyp2c22 cytochrome P450, family 2, subfamily c, polypeptide 22 decreases expression EXP cyhalothrin results in decreased expression of CYP2C22 mRNA CTD PMID:29727961 NCBI chr 1:259,257,658...259,297,270
Ensembl chr 1:259,257,657...259,287,684
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 decreases activity
increases expression
ISO
EXP
cyhalothrin results in decreased activity of CYP2D6 protein
cyhalothrin results in increased expression of CYP2D4 mRNA
CTD PMID:20183062, PMID:29727961 NCBI chr 7:123,599,264...123,608,436
Ensembl chr 7:123,599,266...123,608,436
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases expression EXP cyhalothrin results in increased expression of CYP2E1 mRNA CTD PMID:29727961 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Cyp2t1 cytochrome P450, family 2, subfamily t, polypeptide 1 decreases expression EXP cyhalothrin results in decreased expression of CYP2T1 mRNA CTD PMID:29727961 NCBI chr 1:83,965,370...83,969,466
Ensembl chr 1:83,965,608...83,969,559
JBrowse link
G Cyp3a18 cytochrome P450, family 3, subfamily a, polypeptide 18 increases expression EXP cyhalothrin results in increased expression of CYP3A18 mRNA CTD PMID:29727961 NCBI chr12:10,636,294...10,684,273
Ensembl chr12:10,636,275...10,684,278
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases expression EXP cyhalothrin results in increased expression of CYP3A2 mRNA CTD PMID:29727961 NCBI chr12:11,641,500...11,677,818
Ensembl chr12:11,655,402...11,733,136
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 increases expression EXP cyhalothrin results in increased expression of CYP3A23-3A1 mRNA CTD PMID:29727961 NCBI chr12:11,053,888...11,082,742
Ensembl chr12:11,655,402...11,733,136
JBrowse link
G Cyp4a1 cytochrome P450, family 4, subfamily a, polypeptide 1 increases expression EXP cyhalothrin results in increased expression of CYP4A1 mRNA CTD PMID:29727961 NCBI chr 5:134,492,734...134,507,158
Ensembl chr 5:134,492,756...134,507,154
JBrowse link
G Dlg4 discs large MAGUK scaffold protein 4 multiple interactions
decreases expression
increases expression
ISO
EXP
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [cyhalothrin results in increased expression of DLG4]; cyhalothrin inhibits the reaction [Estradiol results in increased expression of DLG4 protein]; fulvestrant inhibits the reaction [cyhalothrin results in increased expression of DLG4 protein]
cyhalothrin results in decreased expression of DLG4 protein
CTD PMID:26969072, PMID:28487251 NCBI chr10:56,625,845...56,655,543
Ensembl chr10:56,627,411...56,653,599
JBrowse link
G Drd2 dopamine receptor D2 decreases expression EXP cyhalothrin results in decreased expression of DRD2 mRNA; cyhalothrin results in decreased expression of DRD2 protein CTD PMID:22366556, PMID:28495607 NCBI chr 8:53,678,777...53,743,643
Ensembl chr 8:53,678,777...53,743,642
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 increases activity ISO cyhalothrin results in increased activity of EIF4EBP1 CTD PMID:26969072 NCBI chr16:68,954,860...68,968,248
Ensembl chr16:68,954,875...68,968,248
JBrowse link
G Entpd1 ectonucleoside triphosphate diphosphohydrolase 1 increases expression EXP cyhalothrin results in increased expression of ENTPD1 mRNA CTD PMID:31421116 NCBI chr 1:259,692,020...259,818,922
Ensembl chr 1:259,739,955...259,819,494
JBrowse link
G Entpd2 ectonucleoside triphosphate diphosphohydrolase 2 increases expression EXP cyhalothrin results in increased expression of ENTPD2 mRNA CTD PMID:31421116 NCBI chr 3:2,617,795...2,623,818
Ensembl chr 3:2,617,805...2,623,445
JBrowse link
G Entpd3 ectonucleoside triphosphate diphosphohydrolase 3 increases expression EXP cyhalothrin results in increased expression of ENTPD3 mRNA CTD PMID:31421116 NCBI chr 8:129,201,000...129,232,436
Ensembl chr 8:129,201,669...129,232,677
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 affects binding ISO cyhalothrin binds to ERBB2 protein CTD PMID:32278787 NCBI chr10:86,367,596...86,391,728
Ensembl chr10:86,367,596...86,391,728
JBrowse link
G Esr1 estrogen receptor 1 increases activity
increases expression
multiple interactions
decreases expression
EXP
ISO
cyhalothrin results in increased activity of ESR1 protein
cyhalothrin results in increased expression of ESR1
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [cyhalothrin results in increased expression of ESR1]; fulvestrant inhibits the reaction [cyhalothrin results in increased expression of ESR1]
cyhalothrin results in decreased expression of ESR1 mRNA; cyhalothrin results in decreased expression of ESR1 protein
CTD PMID:18419197, PMID:20097460, PMID:20410157, PMID:26969072 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Esr2 estrogen receptor 2 decreases expression ISO cyhalothrin results in decreased expression of ESR2 mRNA; cyhalothrin results in decreased expression of ESR2 protein CTD PMID:18419197 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link
G Fasn fatty acid synthase increases expression EXP cyhalothrin results in increased expression of FASN mRNA; cyhalothrin results in increased expression of FASN protein CTD PMID:27348886 NCBI chr10:109,987,735...110,005,901
Ensembl chr10:109,987,735...110,005,901
JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 affects binding ISO cyhalothrin binds to FGFR2 protein CTD PMID:32278787 NCBI chr 1:200,590,951...200,696,946
Ensembl chr 1:200,590,953...200,696,928
JBrowse link
G Fmo5 flavin containing dimethylaniline monoxygenase 5 increases expression EXP cyhalothrin results in increased expression of FMO5 mRNA CTD PMID:29727961 NCBI chr 2:199,796,870...199,823,927
Ensembl chr 2:199,796,881...199,823,927
JBrowse link
G Fshb follicle stimulating hormone subunit beta decreases expression
increases expression
multiple interactions
EXP cyhalothrin results in decreased expression of FSHB protein
cyhalothrin results in increased expression of FSHB protein
Taurine inhibits the reaction [cyhalothrin results in decreased expression of FSHB protein]
CTD PMID:29506456, PMID:30029170 NCBI chr 3:98,088,321...98,092,131
Ensembl chr 3:98,088,324...98,092,131
JBrowse link
G Gap43 growth associated protein 43 multiple interactions EXP cyhalothrin promotes the reaction [NGF protein results in increased expression of GAP43 mRNA] CTD PMID:28385489 NCBI chr11:58,624,198...58,717,916
Ensembl chr11:58,624,198...58,717,914
JBrowse link
G Gpt glutamic--pyruvic transaminase increases activity EXP cyhalothrin results in increased activity of GPT protein CTD PMID:28058584 NCBI chr 7:117,759,083...117,761,932
Ensembl chr 7:117,759,083...117,761,931
JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 decreases expression EXP cyhalothrin results in decreased expression of GRIN1 mRNA; cyhalothrin results in decreased expression of GRIN1 protein CTD PMID:28487251 NCBI chr 3:2,507,745...2,534,664
Ensembl chr 3:2,506,896...2,534,663
JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B decreases expression EXP cyhalothrin results in decreased expression of GRIN2B mRNA; cyhalothrin results in decreased expression of GRIN2B protein CTD PMID:28487251 NCBI chr 4:169,541,620...170,000,216
Ensembl chr 4:169,560,387...169,999,873
JBrowse link
G Gsr glutathione-disulfide reductase increases activity EXP cyhalothrin results in increased activity of GSR protein CTD PMID:29727961 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G H2ax H2A.X variant histone multiple interactions ISO [fludioxonil co-treated with cyprodinil co-treated with procymidone co-treated with iprodione co-treated with cyhalothrin] results in increased phosphorylation of H2AX protein CTD PMID:22389207 NCBI chr 8:48,665,652...48,666,981
Ensembl chr 8:48,665,652...48,666,981
JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 increases expression EXP cyhalothrin results in increased expression of HPRT1 mRNA CTD PMID:29727961 NCBI chr  X:158,196,640...158,228,815
Ensembl chr  X:158,197,149...158,228,749
JBrowse link
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 decreases expression EXP cyhalothrin results in decreased expression of HSD11B1 mRNA; cyhalothrin results in decreased expression of HSD11B1 protein CTD PMID:30029170 NCBI chr13:111,946,626...111,996,536
Ensembl chr13:111,926,442...111,972,603
JBrowse link
G Hsd17b3 hydroxysteroid (17-beta) dehydrogenase 3 decreases expression
multiple interactions
EXP cyhalothrin results in decreased expression of HSD17B3 mRNA
Taurine inhibits the reaction [cyhalothrin results in decreased expression of HSD17B3 mRNA]
CTD PMID:29506456 NCBI chr17:1,579,319...1,610,745
Ensembl chr17:1,579,319...1,610,745
JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 decreases expression EXP cyhalothrin results in decreased expression of HSD3B1 mRNA; cyhalothrin results in decreased expression of HSD3B1 protein CTD PMID:30029170
G Htr2a 5-hydroxytryptamine receptor 2A increases expression EXP cyhalothrin results in increased expression of HTR2A protein CTD PMID:22366556 NCBI chr15:56,666,152...56,732,469
Ensembl chr15:56,666,012...56,735,382
JBrowse link
G Ifng interferon gamma increases expression
multiple interactions
EXP cyhalothrin results in increased expression of IFNG mRNA; cyhalothrin results in increased expression of IFNG protein
thymoquinone inhibits the reaction [cyhalothrin results in increased expression of IFNG mRNA]; thymoquinone inhibits the reaction [cyhalothrin results in increased expression of IFNG protein]
CTD PMID:26645134 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Il10 interleukin 10 multiple interactions
decreases expression
EXP thymoquinone inhibits the reaction [cyhalothrin results in decreased expression of IL10 mRNA]; thymoquinone inhibits the reaction [cyhalothrin results in decreased expression of IL10 protein]
cyhalothrin results in decreased expression of IL10 mRNA; cyhalothrin results in decreased expression of IL10 protein
CTD PMID:26645134 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases expression
EXP thymoquinone inhibits the reaction [cyhalothrin results in increased expression of IL1B mRNA]; thymoquinone inhibits the reaction [cyhalothrin results in increased expression of IL1B protein]
cyhalothrin results in increased expression of IL1B mRNA; cyhalothrin results in increased expression of IL1B protein
CTD PMID:26645134, PMID:28058584 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il4 interleukin 4 multiple interactions
decreases expression
EXP thymoquinone inhibits the reaction [cyhalothrin results in decreased expression of IL4 mRNA]; thymoquinone inhibits the reaction [cyhalothrin results in decreased expression of IL4 protein]
cyhalothrin results in decreased expression of IL4 mRNA; cyhalothrin results in decreased expression of IL4 protein
CTD PMID:26645134 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression
EXP thymoquinone inhibits the reaction [cyhalothrin results in increased expression of IL6 mRNA]; thymoquinone inhibits the reaction [cyhalothrin results in increased expression of IL6 protein]
cyhalothrin results in increased expression of IL6 mRNA; cyhalothrin results in increased expression of IL6 protein
CTD PMID:26645134, PMID:28058584 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Lep leptin increases expression EXP cyhalothrin results in increased expression of LEP protein CTD PMID:27348886 NCBI chr 4:56,337,695...56,351,818
Ensembl chr 4:56,337,695...56,351,818
JBrowse link
G Lhb luteinizing hormone subunit beta multiple interactions
decreases expression
EXP Taurine inhibits the reaction [cyhalothrin results in decreased expression of LHB protein] CTD PMID:29506456, PMID:30029170 NCBI chr 1:101,409,992...101,413,725
Ensembl chr 1:101,410,019...101,413,724
JBrowse link
G Mapk1 mitogen activated protein kinase 1 decreases expression EXP cyhalothrin results in decreased expression of MAPK1 protein modified form CTD PMID:28487251 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 decreases expression EXP cyhalothrin results in decreased expression of MAPK3 protein modified form CTD PMID:28487251 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mmp9 matrix metallopeptidase 9 affects binding ISO cyhalothrin binds to MMP9 protein CTD PMID:32278787 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Ngf nerve growth factor multiple interactions EXP cyhalothrin promotes the reaction [NGF protein results in decreased expression of TUBA3A mRNA]; cyhalothrin promotes the reaction [NGF protein results in increased expression of CAMK2A mRNA]; cyhalothrin promotes the reaction [NGF protein results in increased expression of CAMK2B mRNA]; cyhalothrin promotes the reaction [NGF protein results in increased expression of GAP43 mRNA]; cyhalothrin promotes the reaction [NGF protein results in increased expression of TUBB3 mRNA] CTD PMID:28385489 NCBI chr 2:204,886,158...204,939,523
Ensembl chr 2:204,886,202...204,940,453
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions ISO cyhalothrin inhibits the reaction [pregna-4,17-diene-3,16-dione results in decreased activity of NR1H4 protein] CTD PMID:25257666 NCBI chr 7:30,003,429...30,162,095
Ensembl chr 7:30,003,429...30,162,056
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity
multiple interactions
ISO
EXP
cyhalothrin results in increased activity of NR1I2 protein; cyhalothrin results in increased activity of NR1I2 protein polymorphism
[procymidone co-treated with iprodione co-treated with cyprodinil co-treated with fludioxonil co-treated with cyhalothrin] results in increased activity of NR1I2 protein; CES1 protein inhibits the reaction [cyhalothrin results in increased activity of NR1I2 protein]; cyhalothrin binds to and results in increased activity of NR1I2 protein
CTD PMID:19249324, PMID:21115097, PMID:25028461 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 multiple interactions ISO cyhalothrin inhibits the reaction [Hydrocortisone results in increased activity of NR3C1 protein] CTD PMID:26647222 NCBI chr18:31,728,373...32,704,022
Ensembl chr18:31,728,373...31,749,647
JBrowse link
G Pgr progesterone receptor increases expression
affects binding
ISO cyhalothrin results in increased expression of PGR mRNA
cyhalothrin binds to PGR protein
CTD PMID:18419197, PMID:32278787 NCBI chr 8:7,128,656...7,187,796
Ensembl chr 8:7,128,656...7,187,796
JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma affects binding ISO cyhalothrin binds to PIK3CG protein CTD PMID:32278787 NCBI chr 6:51,465,696...51,501,234
Ensembl chr 6:51,465,908...51,498,337
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha increases expression EXP cyhalothrin results in increased expression of PPARA mRNA CTD PMID:27348886 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases expression EXP cyhalothrin results in increased expression of PPARG mRNA CTD PMID:27348886 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Ppp1ca protein phosphatase 1 catalytic subunit alpha increases expression EXP cyhalothrin results in increased expression of PPP1CA protein CTD PMID:28495607 NCBI chr 1:219,439,953...219,443,570
Ensembl chr 1:219,439,953...219,443,570
JBrowse link
G Ppp1r1b protein phosphatase 1, regulatory (inhibitor) subunit 1B decreases expression EXP cyhalothrin results in decreased expression of PPP1R1B protein CTD PMID:28495607 NCBI chr10:86,303,727...86,312,770
Ensembl chr10:86,303,727...86,312,762
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit increases expression
multiple interactions
EXP cyhalothrin results in increased expression of RELA mRNA
thymoquinone inhibits the reaction [cyhalothrin results in increased expression of RELA mRNA]
CTD PMID:26645134 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Rora RAR-related orphan receptor A affects binding ISO cyhalothrin binds to RORA protein CTD PMID:32278787 NCBI chr 8:75,515,886...75,616,477
Ensembl chr 8:75,516,904...75,607,212
JBrowse link
G Rorc RAR-related orphan receptor C affects binding ISO cyhalothrin binds to RORC protein CTD PMID:32278787 NCBI chr 2:195,612,471...195,636,797
Ensembl chr 2:195,617,021...195,637,630
JBrowse link
G Rplp1 ribosomal protein lateral stalk subunit P1 increases expression EXP cyhalothrin results in increased expression of RPLP1 mRNA CTD PMID:29727961 NCBI chr 8:66,862,143...66,863,476
Ensembl chr 8:66,862,143...66,863,476
JBrowse link
G Scarb1 scavenger receptor class B, member 1 decreases expression EXP cyhalothrin results in decreased expression of SCARB1 mRNA; cyhalothrin results in decreased expression of SCARB1 protein CTD PMID:30029170 NCBI chr12:36,694,952...36,761,445
Ensembl chr12:36,694,960...36,761,455
JBrowse link
G Scn10a sodium voltage-gated channel alpha subunit 10 multiple interactions
affects activity
EXP cyhalothrin affects the reaction [SCN10A protein results in increased transport of Sodium]
cyhalothrin affects the activity of SCN10A protein
CTD PMID:16051293, PMID:19766671 NCBI chr 8:128,298,593...128,416,896
Ensembl chr 8:128,298,594...128,416,650
JBrowse link
G Slc18a2 solute carrier family 18 member A2 decreases expression EXP cyhalothrin results in decreased expression of SLC18A2 protein CTD PMID:28495607 NCBI chr 1:280,397,831...280,457,968
Ensembl chr 1:280,423,079...280,457,148
JBrowse link
G Slc6a3 solute carrier family 6 member 3 decreases expression EXP cyhalothrin results in decreased expression of SLC6A3 protein CTD PMID:28495607 NCBI chr 1:32,323,011...32,363,983
Ensembl chr 1:32,321,580...32,363,983
JBrowse link
G Sod2 superoxide dismutase 2 increases activity EXP cyhalothrin results in increased activity of SOD2 protein CTD PMID:29727961 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase affects binding ISO cyhalothrin binds to SRC protein CTD PMID:32278787 NCBI chr 3:153,547,807...153,595,643
Ensembl chr 3:153,580,861...153,595,642
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 increases expression EXP cyhalothrin results in increased expression of SREBF1 mRNA CTD PMID:27348886 NCBI chr10:46,570,996...46,593,021
Ensembl chr10:46,570,996...46,593,009
JBrowse link
G Star steroidogenic acute regulatory protein multiple interactions
decreases expression
EXP Taurine inhibits the reaction [cyhalothrin results in decreased expression of STAR mRNA]; Taurine inhibits the reaction [cyhalothrin results in decreased expression of STAR protein]
cyhalothrin results in decreased expression of STAR mRNA; cyhalothrin results in decreased expression of STAR protein
CTD PMID:29506456, PMID:30029170 NCBI chr16:71,036,204...71,040,847
Ensembl chr16:71,036,204...71,040,847
JBrowse link
G Syngap1 synaptic Ras GTPase activating protein 1 increases expression EXP cyhalothrin results in increased expression of SYNGAP1 protein CTD PMID:28487251 NCBI chr20:5,535,434...5,564,657
Ensembl chr20:5,535,432...5,564,437
JBrowse link
G Tff1 trefoil factor 1 increases expression ISO cyhalothrin results in increased expression of TFF1 mRNA CTD PMID:18419197, PMID:20097460 NCBI chr20:9,892,124...9,895,984
Ensembl chr20:9,892,124...9,895,984
JBrowse link
G Th tyrosine hydroxylase decreases expression EXP cyhalothrin results in decreased expression of TH protein CTD PMID:22366556, PMID:28495607 NCBI chr 1:216,073,034...216,080,287
Ensembl chr 1:216,073,031...216,080,287
JBrowse link
G Thrb thyroid hormone receptor beta multiple interactions ISO cyhalothrin inhibits the reaction [Triiodothyronine results in increased activity of THRB protein] CTD PMID:28531659 NCBI chr15:8,890,578...9,239,815
Ensembl chr15:8,890,578...9,086,282
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
EXP thymoquinone inhibits the reaction [cyhalothrin results in increased expression of TNF mRNA]; thymoquinone inhibits the reaction [cyhalothrin results in increased expression of TNF protein]
cyhalothrin results in increased expression of TNF mRNA; cyhalothrin results in increased expression of TNF protein
CTD PMID:26645134, PMID:27348886, PMID:28058584 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tp53 tumor protein p53 increases expression ISO cyhalothrin results in increased expression of TRP53 mRNA CTD PMID:20097460 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Tsc22d3 TSC22 domain family, member 3 multiple interactions ISO cyhalothrin inhibits the reaction [Hydrocortisone results in increased expression of TSC22D3 mRNA] CTD PMID:26647222 NCBI chr  X:111,884,285...111,944,693
Ensembl chr  X:111,884,295...111,887,906
JBrowse link
G Tubb3 tubulin, beta 3 class III multiple interactions EXP cyhalothrin promotes the reaction [NGF protein results in increased expression of TUBB3 mRNA] CTD PMID:28385489 NCBI chr19:56,220,759...56,229,813
Ensembl chr19:56,220,755...56,229,813
JBrowse link
G Xdh xanthine dehydrogenase decreases expression EXP cyhalothrin results in decreased expression of XDH mRNA CTD PMID:29727961 NCBI chr 6:25,149,570...25,211,273
Ensembl chr 6:25,149,235...25,211,494
JBrowse link
cypermethrin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aass aminoadipate-semialdehyde synthase increases expression ISO cypermethrin results in increased expression of AASS mRNA CTD PMID:21142847 NCBI chr 4:50,152,005...50,208,935
Ensembl chr 4:50,152,452...50,200,328
JBrowse link
G Abat 4-aminobutyrate aminotransferase decreases activity ISO cypermethrin results in decreased activity of ABAT protein CTD PMID:24220872 NCBI chr10:7,093,406...7,200,439
Ensembl chr10:7,093,405...7,200,499
JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 decreases expression ISO cypermethrin results in decreased expression of ABCG1 mRNA CTD PMID:25424538 NCBI chr20:9,743,269...9,842,735
Ensembl chr20:9,743,269...9,840,489
JBrowse link
G Acer2 alkaline ceramidase 2 decreases expression ISO cypermethrin results in decreased expression of ACER2 mRNA CTD PMID:29020013 NCBI chr 5:105,230,540...105,279,732
Ensembl chr 5:105,230,580...105,279,731
JBrowse link
G Ache acetylcholinesterase increases activity
affects activity
multiple interactions
decreases activity
EXP cypermethrin results in increased activity of ACHE protein
cypermethrin affects the activity of ACHE protein
[cypermethrin co-treated with fenvalerate] results in decreased activity of ACHE protein; Chlorpyrifos promotes the reaction [cypermethrin results in decreased activity of ACHE protein]; cypermethrin promotes the reaction [Chlorpyrifos results in decreased activity of ACHE protein]
CTD PMID:7595515, PMID:8385837, PMID:10355540, PMID:32006337 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
JBrowse link
G Acot2 acyl-CoA thioesterase 2 decreases expression ISO cypermethrin results in decreased expression of ACOT2 mRNA CTD PMID:29020013 NCBI chr 6:107,460,596...107,468,324
Ensembl chr 6:107,460,668...107,467,487
JBrowse link
G Acox1 acyl-CoA oxidase 1 multiple interactions ISO cypermethrin promotes the reaction [[lard co-treated with Cholesterol co-treated with Sucrose] results in increased expression of ACOX1 mRNA] CTD PMID:24440342 NCBI chr10:104,724,534...104,748,003
Ensembl chr10:104,722,958...104,748,050
JBrowse link
G Adal adenosine deaminase-like increases expression ISO cypermethrin results in increased expression of ADAL mRNA CTD PMID:29020013 NCBI chr 3:113,091,696...113,109,841
Ensembl chr 3:113,102,090...113,108,654
JBrowse link
G Agt angiotensinogen affects expression
multiple interactions
EXP cypermethrin affects the expression of AGT
Sesame Oil affects the reaction [cypermethrin affects the expression of AGT]
CTD PMID:25816392 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions ISO [prothioconazole co-treated with terbutylazine co-treated with bitertanol co-treated with cypermethrin co-treated with Malathion] results in increased activity of AHR protein; cypermethrin inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein] CTD PMID:25684042 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases expression
increases expression
EXP
ISO
cypermethrin results in decreased expression of AKT1 mRNA
cypermethrin results in increased expression of AKT1 mRNA
CTD PMID:22528246, PMID:27704156 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Alb albumin decreases expression
multiple interactions
increases expression
EXP cypermethrin results in decreased expression of ALB mRNA
Sesame Oil inhibits the reaction [cypermethrin results in increased expression of ALB]
CTD PMID:9650644, PMID:11428908, PMID:25816392 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Aldh5a1 aldehyde dehydrogenase 5 family, member A1 decreases expression EXP cypermethrin results in decreased expression of ALDH5A1 mRNA CTD PMID:22528246 NCBI chr17:42,133,076...42,159,413
Ensembl chr17:42,133,076...42,159,413
JBrowse link
G Aldh8a1 aldehyde dehydrogenase 8 family, member A1 decreases expression ISO cypermethrin results in decreased expression of ALDH8A1 mRNA CTD PMID:25424538 NCBI chr 1:16,910,043...16,929,465
Ensembl chr 1:16,910,069...16,930,481
JBrowse link
G Alpl alkaline phosphatase, biomineralization associated multiple interactions
increases activity
ISO
EXP
[cypermethrin co-treated with Chlorpyrifos] results in increased expression of ALPL protein; Plant Extracts inhibits the reaction [[cypermethrin co-treated with Chlorpyrifos] results in increased expression of ALPL protein]
cypermethrin inhibits the reaction [Aldosterone results in increased expression of ALPL mRNA]
cypermethrin results in increased activity of ALPL protein
CTD PMID:15365239, PMID:15991261, PMID:29149346 NCBI chr 5:156,086,496...156,141,513
Ensembl chr 5:156,086,497...156,141,537
JBrowse link
G Als2 alsin Rho guanine nucleotide exchange factor ALS2 increases expression ISO cypermethrin results in increased expression of ALS2 mRNA CTD PMID:21142847 NCBI chr 9:65,961,361...66,034,396
Ensembl chr 9:65,961,346...66,033,871
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 increases expression ISO cypermethrin results in increased expression of APAF1 mRNA CTD PMID:27704156 NCBI chr 7:31,699,309...31,784,192
Ensembl chr 7:31,699,885...31,784,192
JBrowse link
G Apc APC regulator of WNT signaling pathway increases expression ISO
EXP
cypermethrin results in increased expression of APC mRNA CTD PMID:21142847, PMID:22528246 NCBI chr18:27,011,710...27,106,323
Ensembl chr18:27,047,382...27,105,531
JBrowse link
G Apln apelin increases expression ISO cypermethrin results in increased expression of APLN mRNA CTD PMID:29020013 NCBI chr  X:134,856,719...134,866,210
Ensembl chr  X:134,856,726...134,866,210
JBrowse link
G Aplnr apelin receptor increases expression ISO cypermethrin results in increased expression of APLNR mRNA CTD PMID:29020013 NCBI chr 3:72,540,538...72,544,183
Ensembl chr 3:72,540,538...72,544,182
JBrowse link
G Apoa1 apolipoprotein A1 increases expression EXP cypermethrin results in increased expression of APOA1 mRNA CTD PMID:9650644 NCBI chr 8:50,525,091...50,526,875
Ensembl chr 8:50,525,091...50,526,875
JBrowse link
G Apob apolipoprotein B increases expression EXP cypermethrin results in increased expression of APOB mRNA CTD PMID:9650644 NCBI chr 6:33,176,826...33,216,381
Ensembl chr 6:33,176,778...33,224,997
JBrowse link
G Apoe apolipoprotein E decreases expression
increases expression
EXP
ISO
cypermethrin results in decreased expression of APOE mRNA
cypermethrin results in increased expression of APOE mRNA
CTD PMID:9650644, PMID:11428908, PMID:21142847 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
JBrowse link
G Aqr aquarius intron-binding spliceosomal factor increases expression ISO cypermethrin results in increased expression of AQR mRNA CTD PMID:21142847 NCBI chr 3:105,570,399...105,640,431
Ensembl chr 3:105,570,292...105,640,463
JBrowse link
G Ar androgen receptor multiple interactions
decreases expression
decreases activity
ISO
EXP
[bitertanol co-treated with propiconazole co-treated with cypermethrin] inhibits the reaction [Dihydrotestosterone binds to and results in increased activity of AR protein]; [Dihydrotestosterone co-treated with cypermethrin] results in decreased expression of AR mRNA; [terbutylazine co-treated with bitertanol co-treated with propiconazole co-treated with cypermethrin co-treated with Malathion] inhibits the reaction [Dihydrotestosterone binds to and results in increased activity of AR protein]; [terbutylazine co-treated with bitertanol co-treated with propiconazole co-treated with cypermethrin co-treated with Malathion] results in decreased activity of AR protein; cypermethrin inhibits the reaction [Dihydrotestosterone results in increased activity of AR protein]; cypermethrin inhibits the reaction [Metribolone results in increased activity of AR protein]
cypermethrin results in decreased expression of AR protein
cypermethrin results in decreased expression of AR mRNA; cypermethrin results in decreased expression of AR protein
cypermethrin results in decreased activity of AR protein
CTD PMID:16857237, PMID:17980950, PMID:18324785, PMID:20410157, PMID:22147539, PMID:23871939, PMID:24810582 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Arg1 arginase 1 multiple interactions ISO cypermethrin promotes the reaction [Lipopolysaccharides results in increased expression of ARG1 mRNA] CTD PMID:29471534 NCBI chr 1:21,525,421...21,537,872
Ensembl chr 1:21,525,421...21,537,863
JBrowse link
G Armcx5 armadillo repeat containing, X-linked 5 decreases expression ISO cypermethrin results in decreased expression of ARMCX5 mRNA CTD PMID:29020013 NCBI chr  X:106,252,677...106,255,383
Ensembl chr  X:106,253,355...106,255,058
JBrowse link
G Atg12 autophagy related 12 increases expression ISO cypermethrin results in increased expression of ATG12 mRNA CTD PMID:27704156 NCBI chr18:40,721,799...40,732,143
Ensembl chr18:40,721,800...40,732,126
JBrowse link
G Atg3 autophagy related 3 increases expression ISO cypermethrin results in increased expression of ATG3 mRNA CTD PMID:27704156 NCBI chr11:60,585,192...60,613,706
Ensembl chr11:60,585,171...60,613,718
JBrowse link
G Atg5 autophagy related 5 increases expression ISO cypermethrin results in increased expression of ATG5 mRNA CTD PMID:27704156 NCBI chr20:49,301,783...49,393,147
Ensembl chr20:49,318,308...49,393,140
JBrowse link
G Atg7 autophagy related 7 increases expression ISO cypermethrin results in increased expression of ATG7 mRNA CTD PMID:27704156 NCBI chr 4:146,570,113...146,777,093
Ensembl chr 4:146,598,413...146,777,124
JBrowse link
G Atm ATM serine/threonine kinase increases expression ISO cypermethrin results in increased expression of ATM mRNA CTD PMID:21142847 NCBI chr 8:58,015,938...58,119,973
Ensembl chr 8:58,015,940...58,120,045
JBrowse link
G Atp5md ATP synthase membrane subunit DAPIT decreases expression ISO cypermethrin results in decreased expression of ATP5MD mRNA CTD PMID:29020013 NCBI chr 1:266,859,961...266,866,753
Ensembl chr 1:266,862,579...266,862,842
JBrowse link
G Atp5pd ATP synthase peripheral stalk subunit d decreases expression
multiple interactions
EXP cypermethrin results in decreased expression of ATP5H protein
Minocycline inhibits the reaction [cypermethrin results in decreased expression of ATP5H protein]
CTD PMID:21561882 NCBI chr10:103,967,340...103,972,552
Ensembl chr10:103,967,312...103,972,668
JBrowse link
G Atp6v1f ATPase H+ transporting V1 subunit F increases expression EXP cypermethrin results in increased expression of ATP6V1F mRNA CTD PMID:22528246 NCBI chr 4:56,744,563...56,747,657
Ensembl chr 4:56,744,561...56,747,656
JBrowse link
G Atp6v1g2 ATPase H+ transporting V1 subunit G2 increases expression ISO cypermethrin results in increased expression of ATP6V1G2 mRNA CTD PMID:27704156 NCBI chr20:4,821,265...4,824,829
Ensembl chr20:4,821,285...4,823,494
JBrowse link
G Atrx ATRX, chromatin remodeler increases expression ISO cypermethrin results in increased expression of ATRX mRNA CTD PMID:21142847 NCBI chr  X:76,820,110...76,979,155
Ensembl chr  X:76,692,970...76,708,878
Ensembl chr  X:76,692,970...76,708,878
JBrowse link
G B3galt4 Beta-1,3-galactosyltransferase 4 increases expression ISO cypermethrin results in increased expression of B3GALT4 mRNA CTD PMID:29020013 NCBI chr20:5,446,104...5,447,679
Ensembl chr20:5,446,104...5,447,673
JBrowse link
G Bambi BMP and activin membrane-bound inhibitor increases expression ISO cypermethrin results in increased expression of BAMBI mRNA CTD PMID:29020013 NCBI chr17:56,905,419...56,909,675
Ensembl chr17:56,905,112...56,909,992
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
multiple interactions
affects localization
EXP
ISO
cypermethrin results in increased expression of BAX mRNA; cypermethrin results in increased expression of BAX protein
Acetylcysteine inhibits the reaction [cypermethrin results in increased expression of BAX mRNA]
cypermethrin affects the localization of BAX protein
Cyclosporine inhibits the reaction [cypermethrin affects the localization of BAX protein]; HBEGF protein inhibits the reaction [cypermethrin results in increased expression of BAX protein]; Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [cypermethrin affects the localization of BAX protein]
CTD PMID:22048644, PMID:22528246, PMID:25370934, PMID:29945211, PMID:32028016 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
increases expression
decreases expression
EXP
ISO
HBEGF protein inhibits the reaction [cypermethrin results in decreased expression of BCL2 protein]
cypermethrin results in increased expression of BCL2 mRNA
cypermethrin results in decreased expression of BCL2 mRNA; cypermethrin results in decreased expression of BCL2 protein
CTD PMID:22048644, PMID:22528246, PMID:27704156, PMID:32028016 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions
increases expression
decreases expression
EXP
ISO
HBEGF protein inhibits the reaction [cypermethrin results in decreased expression of BCL2L1 protein]
cypermethrin results in increased expression of BCL2L1 mRNA
CTD PMID:22048644, PMID:27704156 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Bcl6 BCL6, transcription repressor multiple interactions ISO [[[cypermethrin results in decreased expression of MIR155 mRNA] which results in increased expression of BCL6 mRNA] which results in decreased expression of MAP2K4 protein] which results in decreased phosphorylation of and results in decreased activity of MAPK8 protein; [[[cypermethrin results in decreased expression of MIR155 mRNA] which results in increased expression of BCL6 mRNA] which results in decreased expression of MAP2K4 protein] which results in decreased phosphorylation of and results in decreased activity of MAPK9 protein; [[cypermethrin results in decreased expression of MIR155 mRNA] which results in increased expression of BCL6 mRNA] which results in decreased expression of MAP2K4 protein; [cypermethrin results in decreased expression of MIR155 mRNA] which results in increased expression of BCL6 mRNA CTD PMID:29471534 NCBI chr11:80,255,790...80,279,075
Ensembl chr11:80,255,790...80,279,075
JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions
increases expression
ISO
EXP
cypermethrin inhibits the reaction [Veratridine results in increased expression of BDNF mRNA]
cypermethrin results in increased expression of BDNF mRNA
CTD PMID:11082455, PMID:16166269 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 increases expression ISO cypermethrin results in increased expression of BIRC2 mRNA CTD PMID:27704156 NCBI chr 8:6,014,014...6,036,668
Ensembl chr 8:6,013,207...6,034,142
JBrowse link
G Bmf Bcl2 modifying factor increases expression ISO cypermethrin results in increased expression of BMF mRNA CTD PMID:27704156 NCBI chr 3:110,303,515...110,324,125
Ensembl chr 3:110,306,067...110,324,084
JBrowse link
G Bnip3 BCL2 interacting protein 3 increases expression ISO cypermethrin results in increased expression of BNIP3 mRNA CTD PMID:32028016 NCBI chr 1:211,248,098...211,265,282
Ensembl chr 1:211,248,098...211,265,282
JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase increases expression EXP cypermethrin results in increased expression of BRAF mRNA CTD PMID:22528246 NCBI chr 4:67,389,331...67,520,549
Ensembl chr 4:67,396,192...67,520,356
JBrowse link
G C1galt1c1 C1GALT1-specific chaperone 1 increases expression ISO cypermethrin results in increased expression of C1GALT1C1 mRNA CTD PMID:29020013 NCBI chr  X:124,921,686...124,926,171
Ensembl chr  X:124,921,728...124,926,171
JBrowse link
G C1qtnf9 C1q and TNF related 9 decreases expression ISO cypermethrin results in decreased expression of C1QTNF9 mRNA CTD PMID:29020013 NCBI chr15:41,069,579...41,080,961
Ensembl chr15:41,069,507...41,081,159
JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha increases expression ISO cypermethrin results in increased expression of CAMK2A mRNA CTD PMID:32028016 NCBI chr18:56,193,978...56,295,869
Ensembl chr18:56,193,978...56,295,869
JBrowse link
G Camk2b calcium/calmodulin-dependent protein kinase II beta increases expression ISO cypermethrin results in increased expression of CAMK2B mRNA CTD PMID:32028016 NCBI chr14:86,208,876...86,297,727
Ensembl chr14:86,208,901...86,297,652
JBrowse link
G Casp1 caspase 1 increases expression EXP cypermethrin results in increased expression of CASP1 mRNA CTD PMID:22528246 NCBI chr 8:2,605,743...2,614,637
Ensembl chr 8:2,604,962...2,614,631
JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
increases expression
ISO
EXP
Acetylcysteine inhibits the reaction [cypermethrin results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [cypermethrin results in increased expression of CASP3 mRNA]; cypermethrin inhibits the reaction [Docosahexaenoic Acids results in increased cleavage of and results in increased activity of CASP3 protein]
cypermethrin results in increased expression of CASP3 protein
[cypermethrin co-treated with Chlorpyrifos co-treated with profenofos] results in increased cleavage of CASP3 protein
cypermethrin results in increased cleavage of and results in increased activity of CASP3 protein
CTD PMID:11341974, PMID:21987380, PMID:22048644, PMID:25370934, PMID:27704156, PMID:29945211, PMID:32028016 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp6 caspase 6 increases expression EXP cypermethrin results in increased expression of CASP6 mRNA CTD PMID:22528246 NCBI chr 2:235,341,326...235,353,715
Ensembl chr 2:235,341,365...235,353,967
Ensembl chr 2:235,341,365...235,353,967
JBrowse link
G Casp7 caspase 7 multiple interactions
increases expression
EXP
ISO
cypermethrin results in increased cleavage of and results in increased activity of CASP7 protein
cypermethrin results in increased expression of CASP7 mRNA
CTD PMID:22048644, PMID:27704156 NCBI chr 1:277,190,557...277,242,779
Ensembl chr 1:277,190,964...277,242,774
JBrowse link
G Casp9 caspase 9 multiple interactions
increases expression
EXP
ISO
cypermethrin results in increased cleavage of and results in increased activity of CASP9 protein
Acetylcysteine inhibits the reaction [cypermethrin results in increased expression of CASP9 mRNA]
CTD PMID:22048644, PMID:22528246, PMID:27704156, PMID:29945211 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cat catalase multiple interactions
affects binding
decreases activity
affects activity
increases expression
increases activity
ISO
EXP
[cypermethrin co-treated with Chlorpyrifos] results in decreased activity of CAT protein; [propetamphos co-treated with cypermethrin] results in decreased activity of CAT protein; Plant Extracts inhibits the reaction [[cypermethrin co-treated with Chlorpyrifos] results in decreased activity of CAT protein]
cypermethrin binds to CAT protein
cypermethrin results in decreased activity of CAT protein
cypermethrin affects the activity of CAT protein
cypermethrin results in increased expression of CAT mRNA
cypermethrin results in increased activity of CAT protein
[cypermethrin co-treated with fenvalerate] results in increased activity of CAT protein; [cypermethrin co-treated with propetamphos] results in decreased activity of CAT protein; Sesame Oil affects the reaction [cypermethrin affects the activity of CAT protein]
CTD PMID:10355540, PMID:12965126, PMID:15365239, PMID:15991261, PMID:18214882, PMID:21142847, PMID:21397294, PMID:23900960, PMID:25816392, PMID:25926273, PMID:28584332, PMID:32214279, PMID:32278787 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Ccl7 C-C motif chemokine ligand 7 multiple interactions ISO cypermethrin promotes the reaction [Lipopolysaccharides results in increased expression of CCL7 mRNA] CTD PMID:29471534 NCBI chr10:69,423,083...69,424,933
Ensembl chr10:69,423,086...69,424,979
JBrowse link
G Ccna1 cyclin A1 decreases expression ISO cypermethrin results in decreased expression of CCNA1 mRNA CTD PMID:24810582 NCBI chr 2:144,456,689...144,503,570
Ensembl chr 2:144,458,153...144,467,912
JBrowse link
G Ccna2 cyclin A2 decreases expression EXP cypermethrin results in decreased expression of CCNA2 mRNA CTD PMID:22528246 NCBI chr 2:123,274,727...123,282,266
Ensembl chr 2:123,275,881...123,282,214
JBrowse link
G Ccnd1 cyclin D1 increases expression
multiple interactions
ISO cypermethrin results in increased expression of CCND1 mRNA
fulvestrant inhibits the reaction [cypermethrin results in increased expression of CCND1 mRNA]
CTD PMID:26877835 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Ccnd2 cyclin D2 increases expression
decreases expression
EXP
ISO
cypermethrin results in increased expression of CCND2 mRNA
cypermethrin results in decreased expression of CCND2 mRNA
CTD PMID:22528246, PMID:24810582 NCBI chr 4:159,674,885...159,697,207
Ensembl chr 4:159,674,885...159,697,207
JBrowse link
G Ccs copper chaperone for superoxide dismutase increases expression ISO cypermethrin results in increased expression of CCS mRNA CTD PMID:21142847 NCBI chr 1:220,075,251...220,096,319
Ensembl chr 1:220,075,247...220,096,404
JBrowse link
G Cd93 CD93 molecule increases expression ISO cypermethrin results in increased expression of CD93 mRNA CTD PMID:29020013 NCBI chr 3:142,778,798...142,783,774
Ensembl chr 3:142,778,770...142,783,774
JBrowse link
G Cdh12 cadherin 12 increases expression EXP cypermethrin results in increased expression of CDH12 mRNA CTD PMID:22528246 NCBI chr 2:71,310,228...72,540,063
Ensembl chr 2:72,006,099...72,540,263
JBrowse link
G Cdk9 cyclin-dependent kinase 9 decreases expression EXP cypermethrin results in decreased expression of CDK9 mRNA CTD PMID:22528246 NCBI chr 3:11,742,269...11,747,117
Ensembl chr 3:11,742,266...11,747,113
JBrowse link
G Cdkn2b cyclin-dependent kinase inhibitor 2B increases expression EXP cypermethrin results in increased expression of CDKN2B mRNA CTD PMID:22528246 NCBI chr 5:107,834,353...107,857,428
Ensembl chr 5:107,845,951...107,858,104
JBrowse link
G Cebpe CCAAT/enhancer binding protein epsilon multiple interactions ISO Acetylcysteine inhibits the reaction [cypermethrin inhibits the reaction [Tretinoin results in increased expression of CEBPE mRNA]]; cypermethrin inhibits the reaction [Tretinoin results in increased expression of CEBPE mRNA] CTD PMID:29945211 NCBI chr15:33,356,119...33,357,517
Ensembl chr15:33,355,947...33,358,138
JBrowse link
G Cenpa centromere protein A increases expression ISO cypermethrin results in increased expression of CENPA mRNA CTD PMID:29020013 NCBI chr 6:27,072,259...27,080,863
Ensembl chr 6:27,072,166...27,080,856
JBrowse link
G Ces1d carboxylesterase 1D increases hydrolysis ISO CES1 protein results in increased hydrolysis of cypermethrin CTD PMID:16359636 NCBI chr19:15,195,514...15,239,827
Ensembl chr19:15,033,108...15,239,821
JBrowse link
G Ces2h carboxylesterase 2H increases hydrolysis ISO CES2 protein results in increased hydrolysis of cypermethrin CTD PMID:16359636 NCBI chr19:37,052,555...37,067,176
Ensembl chr19:37,052,556...37,067,156
JBrowse link
G Cga glycoprotein hormones, alpha polypeptide increases expression
multiple interactions
ISO cypermethrin results in increased expression of CGA mRNA
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [cypermethrin results in increased expression of CGA mRNA]; 2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide inhibits the reaction [cypermethrin results in increased expression of CGA mRNA]; bisindolylmaleimide I inhibits the reaction [cypermethrin results in increased expression of CGA mRNA]; Egtazic Acid inhibits the reaction [cypermethrin results in increased expression of CGA mRNA]; Nimodipine inhibits the reaction [cypermethrin results in increased expression of CGA mRNA]
CTD PMID:28731686, PMID:29149324 NCBI chr 5:50,362,491...50,393,368
Ensembl chr 5:50,381,244...50,393,367
JBrowse link
G Chac1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 increases expression ISO cypermethrin results in increased expression of CHAC1 mRNA CTD PMID:25424538 NCBI chr 3:111,160,205...111,163,425
Ensembl chr 3:111,160,205...111,163,425
JBrowse link
G Chat choline O-acetyltransferase decreases expression EXP cypermethrin results in decreased expression of CHAT mRNA; cypermethrin results in decreased expression of CHAT protein CTD PMID:26115703 NCBI chr16:8,576,858...8,686,131
Ensembl chr16:8,577,840...8,686,131
JBrowse link
G Chchd2 coiled-coil-helix-coiled-coil-helix domain containing 2 increases expression ISO cypermethrin results in increased expression of CHCHD2 mRNA CTD PMID:29020013 NCBI chr 9:101,388,148...101,388,819
Ensembl chr 9:101,388,151...101,388,833
JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2 multiple interactions
decreases expression
EXP cypermethrin promotes the reaction [cypermethrin results in decreased expression of CHRM2 mRNA]; cypermethrin promotes the reaction [cypermethrin results in decreased expression of CHRM2 protein]
cypermethrin results in decreased expression of CHRM2 mRNA; cypermethrin results in decreased expression of CHRM2 protein
CTD PMID:25288152 NCBI chr 4:64,089,028...64,091,090
Ensembl chr 4:64,088,900...64,091,090
JBrowse link
G Cldn5 claudin 5 increases expression ISO cypermethrin results in increased expression of CLDN5 mRNA CTD PMID:29020013 NCBI chr11:86,356,292...86,357,718
Ensembl chr11:86,356,294...86,357,718
JBrowse link
G Commd4 COMM domain containing 4 increases expression ISO cypermethrin results in increased expression of COMMD4 mRNA CTD PMID:27704156 NCBI chr 8:61,833,340...61,836,872
Ensembl chr 8:61,833,326...61,836,945
JBrowse link
G Copg2 COPI coat complex subunit gamma 2 decreases expression EXP cypermethrin results in decreased expression of COPG2 mRNA CTD PMID:22528246 NCBI chr 4:58,064,394...58,195,242
Ensembl chr 4:58,064,833...58,195,143
JBrowse link
G Cox14 cytochrome c oxidase assembly factor COX14 increases expression ISO cypermethrin results in increased expression of COX14 mRNA CTD PMID:29020013 NCBI chr 7:141,378,537...141,380,960
Ensembl chr 7:141,380,322...141,380,495
JBrowse link
G Cox7c cytochrome c oxidase subunit 7C decreases expression ISO cypermethrin results in decreased expression of COX7C mRNA CTD PMID:29020013 NCBI chr 2:14,699,878...14,701,903
Ensembl chr 2:14,699,882...14,701,903
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A multiple interactions ISO cypermethrin promotes the reaction [[lard co-treated with Cholesterol co-treated with Sucrose] results in increased expression of CPT1A mRNA] CTD PMID:24440342 NCBI chr 1:218,568,157...218,629,679
Ensembl chr 1:218,569,510...218,629,678
JBrowse link
G Crlf1 cytokine receptor-like factor 1 decreases expression EXP cypermethrin results in decreased expression of CRLF1 mRNA CTD PMID:22528246 NCBI chr16:20,675,042...20,686,365
Ensembl chr16:20,675,042...20,686,317
JBrowse link
G Cry2 cryptochrome circadian regulator 2 increases expression ISO cypermethrin results in increased expression of CRY2 mRNA CTD PMID:21142847 NCBI chr 3:81,314,151...81,344,143
Ensembl chr 3:81,314,149...81,344,110
JBrowse link
G Csf3r colony stimulating factor 3 receptor multiple interactions ISO Acetylcysteine inhibits the reaction [cypermethrin inhibits the reaction [Tretinoin results in increased expression of CSF3R mRNA]]; cypermethrin inhibits the reaction [Tretinoin results in increased expression of CSF3R mRNA] CTD PMID:29945211 NCBI chr 5:144,031,353...144,051,966
Ensembl chr 5:144,031,402...144,051,600
JBrowse link
G Ctsb cathepsin B increases expression ISO cypermethrin results in increased expression of CTSB mRNA CTD PMID:27704156 NCBI chr15:46,316,741...46,337,613
Ensembl chr15:46,316,741...46,337,612
JBrowse link
G Cycs cytochrome c, somatic affects localization
increases activity
multiple interactions
EXP cypermethrin affects the localization of CYCS protein
cypermethrin results in increased activity of CYCS protein
[propetamphos co-treated with cypermethrin] results in increased activity of CYCS protein
CTD PMID:22528246, PMID:25926273 NCBI chr 4:80,331,226...80,333,326
Ensembl chr 4:80,331,227...80,333,326
JBrowse link
G Cygb cytoglobin increases expression ISO cypermethrin results in increased expression of CYGB mRNA CTD PMID:21142847 NCBI chr10:105,618,325...105,628,091
Ensembl chr10:105,618,326...105,628,091
JBrowse link
G Cyld CYLD lysine 63 deubiquitinase increases expression ISO cypermethrin results in increased expression of CYLD mRNA CTD PMID:27704156 NCBI chr19:19,264,984...19,323,817
Ensembl chr19:19,265,164...19,315,357
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 decreases expression
increases expression
multiple interactions
ISO cypermethrin results in decreased expression of CYP11A1 mRNA
cypermethrin results in increased expression of CYP11A1 mRNA
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [cypermethrin results in increased expression of CYP11A1 mRNA]; Egtazic Acid inhibits the reaction [cypermethrin results in increased expression of CYP11A1 mRNA]; Nimodipine inhibits the reaction [cypermethrin results in increased expression of CYP11A1 mRNA]
CTD PMID:20131380, PMID:21560301, PMID:24810582, PMID:28731686 NCBI chr 8:62,798,317...62,809,848
Ensembl chr 8:62,779,875...62,809,893
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 decreases expression ISO cypermethrin results in decreased expression of CYP17A1 mRNA; cypermethrin results in decreased expression of CYP17A1 protein CTD PMID:21397294, PMID:21560301, PMID:24810582 NCBI chr 1:266,422,127...266,429,947
Ensembl chr 1:266,422,132...266,428,239
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 increases activity
increases expression
multiple interactions
ISO
EXP
cypermethrin results in increased activity of CYP19A1 protein
cypermethrin results in increased expression of CYP19A1 mRNA
[bitertanol co-treated with propiconazole co-treated with cypermethrin co-treated with Malathion co-treated with terbutylazine] results in increased expression of CYP19A1 mRNA
CTD PMID:16996190, PMID:23954766, PMID:24810582 NCBI chr 8:58,744,849...58,772,408
Ensembl chr 8:58,744,849...58,772,408
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases activity
affects expression
increases expression
ISO
EXP
cypermethrin results in decreased activity of CYP1A1 protein
cypermethrin affects the expression of CYP1A1 mRNA
cypermethrin results in increased expression of CYP1A1 mRNA
CTD PMID:18420780, PMID:23447098, PMID:26115703, PMID:32214279 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases activity
increases expression
ISO
EXP
cypermethrin results in decreased activity of CYP1A2 protein
cypermethrin results in increased expression of CYP1A2 mRNA
CTD PMID:18420780, PMID:23447098, PMID:26115703 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases activity
affects expression
increases expression
ISO cypermethrin results in decreased activity of CYP1B1 protein
cypermethrin affects the expression of CYP1B1 mRNA
cypermethrin results in increased expression of CYP1B1
CTD PMID:18420780, PMID:32214279 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 decreases activity
increases expression
ISO
EXP
cypermethrin results in decreased activity of CYP2B10 protein
cypermethrin results in increased expression of CYP2B1 mRNA
CTD PMID:11377398, PMID:18420780, PMID:23447098, PMID:26115703 NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783
JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 increases expression EXP cypermethrin results in increased expression of CYP2B2 mRNA CTD PMID:23447098, PMID:26115703 NCBI chr 1:83,103,925...83,119,578
Ensembl chr 1:83,103,925...83,119,193
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases activity
increases expression
ISO cypermethrin results in increased activity of CYP2B6 protein
cypermethrin results in increased expression of CYP2B6 mRNA; cypermethrin results in increased expression of CYP2B6 protein
CTD PMID:15548381, PMID:22310298 NCBI chr 1:83,163,103...83,236,615
Ensembl chr 1:83,163,079...83,236,615
JBrowse link
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 increases expression ISO cypermethrin results in increased expression of CYP2C19 mRNA CTD PMID:22310298 NCBI chr 1:147,713,879...147,814,410
Ensembl chr 1:147,713,892...147,888,007
JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 increases expression
decreases activity
ISO cypermethrin results in increased expression of CYP2C8 mRNA
cypermethrin results in decreased activity of CYP2C29 protein
CTD PMID:18420780, PMID:22310298 NCBI chr 1:147,236,480...147,307,988 JBrowse link
G Cyp2d1 cytochrome P450, family 2, subfamily d, polypeptide 1 multiple interactions
increases expression
EXP cypermethrin promotes the reaction [cypermethrin results in increased expression of CYP2D1 mRNA]; cypermethrin promotes the reaction [cypermethrin results in increased expression of CYP2D1 protein]
cypermethrin results in increased expression of CYP2D1 mRNA; cypermethrin results in increased expression of CYP2D1 protein
CTD PMID:25288152 NCBI chr 7:123,625,641...123,630,045
Ensembl chr 7:123,625,590...123,638,765
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 decreases activity ISO cypermethrin results in decreased activity of CYP2D6 protein CTD PMID:18420780 NCBI chr 7:123,599,264...123,608,436
Ensembl chr 7:123,599,266...123,608,436
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases activity
increases activity
multiple interactions
increases expression
ISO
EXP
cypermethrin results in decreased activity of CYP2E1 protein
cypermethrin results in increased activity of CYP2E1 protein
[cypermethrin co-treated with propetamphos] results in increased activity of CYP2E1 protein
cypermethrin results in increased expression of CYP2E1 mRNA; cypermethrin results in increased expression of CYP2E1 protein
cypermethrin inhibits the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone]
CTD PMID:18420780, PMID:20815782, PMID:22634058, PMID:23447098, PMID:25926273, PMID:26115703 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 multiple interactions
increases expression
EXP cypermethrin promotes the reaction [cypermethrin results in increased expression of CYP3A23-3A1 mRNA]; cypermethrin promotes the reaction [cypermethrin results in increased expression of CYP3A23-3A1 protein]
cypermethrin results in increased expression of CYP3A23-3A1 mRNA; cypermethrin results in increased expression of CYP3A23-3A1 protein
CTD PMID:25288152 NCBI chr12:11,053,888...11,082,742
Ensembl chr12:11,655,402...11,733,136
JBrowse link
G Dap3 death associated protein 3 increases expression EXP cypermethrin results in increased expression of DAP3 mRNA CTD PMID:22528246 NCBI chr 2:188,225,607...188,255,324
Ensembl chr 2:188,225,613...188,252,725
JBrowse link
G Dbi diazepam binding inhibitor, acyl-CoA binding protein decreases expression ISO cypermethrin results in decreased expression of DBI mRNA CTD PMID:29020013 NCBI chr13:36,147,667...36,156,076
Ensembl chr13:36,117,119...36,174,908
JBrowse link
G Dennd4a DENN domain containing 4A increases expression ISO cypermethrin results in increased expression of DENND4A mRNA CTD PMID:27704156 NCBI chr 8:70,293,355...70,406,675
Ensembl chr 8:70,317,586...70,406,751
JBrowse link
G Depp1 DEPP1, autophagy regulator decreases expression ISO cypermethrin results in decreased expression of DEPP1 mRNA CTD PMID:29020013 NCBI chr 4:148,780,330...148,784,566
Ensembl chr 4:148,782,479...148,784,562
JBrowse link
G Dgat1 diacylglycerol O-acyltransferase 1 multiple interactions ISO [lard co-treated with Cholesterol co-treated with Sucrose co-treated with cypermethrin] results in increased expression of DGAT1 mRNA CTD PMID:24440342 NCBI chr 7:117,566,363...117,576,735
Ensembl chr 7:117,566,368...117,576,737
JBrowse link
G Dmrta1 DMRT-like family A1 increases expression ISO cypermethrin results in increased expression of DMRTA1 mRNA CTD PMID:29020013 NCBI chr 5:108,278,217...108,284,757
Ensembl chr 5:108,278,217...108,284,757
JBrowse link
G Drd2 dopamine receptor D2 multiple interactions
decreases expression
EXP cypermethrin inhibits the reaction [[Quinpirole binds to and results in increased activity of DRD2 protein] which results in increased uptake of Dopamine]; cypermethrin promotes the reaction [cypermethrin results in decreased expression of DRD2 mRNA]; cypermethrin promotes the reaction [cypermethrin results in decreased expression of DRD2 protein]
cypermethrin results in decreased expression of DRD2 mRNA; cypermethrin results in decreased expression of DRD2 protein
CTD PMID:10936494, PMID:25288152 NCBI chr 8:53,678,777...53,743,643
Ensembl chr 8:53,678,777...53,743,642
JBrowse link
G Duox1 dual oxidase 1 increases expression ISO cypermethrin results in increased expression of DUOX1 mRNA CTD PMID:21142847 NCBI chr 3:114,251,794...114,286,827
Ensembl chr 3:114,253,637...114,286,802
JBrowse link
G Egfr epidermal growth factor receptor affects binding
decreases phosphorylation
decreases expression
EXP cypermethrin binds to EGFR protein
cypermethrin results in decreased phosphorylation of EGFR protein
cypermethrin results in decreased expression of EGFR mRNA; cypermethrin results in decreased expression of EGFR protein
CTD PMID:22048644 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
JBrowse link
G Egr1 early growth response 1 multiple interactions
increases expression
ISO 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [cypermethrin results in increased expression of EGR1 protein]; bisindolylmaleimide I inhibits the reaction [cypermethrin results in increased expression of EGR1 protein]; Egtazic Acid inhibits the reaction [cypermethrin results in increased expression of EGR1 protein]
cypermethrin results in increased expression of EGR1 mRNA; cypermethrin results in increased expression of EGR1 protein
CTD PMID:29149324 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
JBrowse link
G Eif4e eukaryotic translation initiation factor 4E increases expression ISO cypermethrin results in increased expression of EIF4E mRNA CTD PMID:29020013 NCBI chr 2:243,819,616...243,853,987
Ensembl chr 2:243,820,661...243,852,631
JBrowse link
G Ephx1 epoxide hydrolase 1 increases expression EXP cypermethrin results in increased expression of EPHX1 mRNA CTD PMID:22528246 NCBI chr13:99,271,390...99,300,580
Ensembl chr13:99,271,366...99,300,579
JBrowse link
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit decreases expression EXP cypermethrin results in decreased expression of ERCC2 mRNA CTD PMID:22528246 NCBI chr 1:80,293,574...80,307,334
Ensembl chr 1:80,293,566...80,307,344
JBrowse link
G Ercc6 ERCC excision repair 6, chromatin remodeling factor increases expression ISO cypermethrin results in increased expression of ERCC6 mRNA CTD PMID:21142847 NCBI chr16:8,734,028...8,804,610
Ensembl chr16:8,734,035...8,804,610
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions
increases expression
decreases expression
affects binding
increases activity
ISO
EXP
cypermethrin metabolite binds to and results in increased activity of ESR1 protein
cypermethrin inhibits the reaction [Estradiol results in increased activity of ESR1 protein]
cypermethrin results in increased expression of ESR1 mRNA; cypermethrin results in increased expression of ESR1 protein
cypermethrin results in decreased expression of ESR1 mRNA; cypermethrin results in decreased expression of ESR1 protein
cypermethrin binds to ESR1 protein
cypermethrin results in increased activity of ESR1 protein
CTD PMID:12396874, PMID:15064155, PMID:16395479, PMID:20397420, PMID:20574910, PMID:24388911, PMID:24810582, PMID:28531659, PMID:29253587 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Esr2 estrogen receptor 2 increases expression ISO cypermethrin results in increased expression of ESR2 mRNA CTD PMID:20574910 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link
G F3 coagulation factor III, tissue factor decreases expression ISO cypermethrin results in decreased expression of F3 mRNA CTD PMID:29020013 NCBI chr 2:225,310,686...225,322,281
Ensembl chr 2:225,310,624...225,322,272
JBrowse link
G Fancc FA complementation group C increases expression ISO cypermethrin results in increased expression of FANCC mRNA CTD PMID:21142847 NCBI chr17:826,512...955,703
Ensembl chr17:833,509...955,615
JBrowse link
G Fancg FA complementation group G increases expression ISO cypermethrin results in increased expression of FANCG mRNA CTD PMID:21142847 NCBI chr 5:58,448,060...58,456,416
Ensembl chr 5:58,448,822...58,455,819
JBrowse link
G Fas Fas cell surface death receptor increases expression ISO cypermethrin results in increased expression of FAS mRNA CTD PMID:27704156 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Fau FAU, ubiquitin like and ribosomal protein S30 fusion decreases expression ISO cypermethrin results in decreased expression of FAU mRNA CTD PMID:29020013 NCBI chr 1:221,420,312...221,421,827
Ensembl chr 1:221,420,271...221,421,842
JBrowse link
G Fgf5 fibroblast growth factor 5 decreases expression ISO cypermethrin results in decreased expression of FGF5 mRNA CTD PMID:32214279 NCBI chr14:12,974,921...12,996,046
Ensembl chr14:12,974,921...12,995,584
JBrowse link
G Fmo2 flavin containing dimethylaniline monoxygenase 2 increases expression ISO cypermethrin results in increased expression of FMO2 mRNA CTD PMID:21142847 NCBI chr13:80,752,526...80,775,264
Ensembl chr13:80,755,058...80,775,264
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
ISO
EXP
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [cypermethrin results in increased expression of FOS protein]; bisindolylmaleimide I inhibits the reaction [cypermethrin results in increased expression of FOS protein]; cypermethrin inhibits the reaction [Veratridine results in increased expression of FOS mRNA]; Egtazic Acid inhibits the reaction [cypermethrin results in increased expression of FOS protein]
cypermethrin results in increased expression of FOS mRNA; cypermethrin results in increased expression of FOS protein
CTD PMID:8856738, PMID:11082455, PMID:29149324 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Foxa2 forkhead box A2 increases expression ISO cypermethrin results in increased expression of FOXA2 mRNA CTD PMID:32214279 NCBI chr 3:142,383,084...142,387,493
Ensembl chr 3:142,383,278...142,387,481
JBrowse link
G Foxf2 forkhead box F2 decreases expression EXP cypermethrin results in decreased expression of FOXF2 mRNA CTD PMID:22528246 NCBI chr17:34,150,417...34,156,450 JBrowse link
G Fshb follicle stimulating hormone subunit beta increases expression
increases secretion
multiple interactions
decreases expression
EXP
ISO
cypermethrin results in increased expression of FSHB protein
cypermethrin results in increased secretion of FSHB protein
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [cypermethrin results in increased expression of FSHB mRNA]; 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [cypermethrin results in increased secretion of FSHB protein]; 2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide inhibits the reaction [cypermethrin results in increased expression of FSHB mRNA]; bisindolylmaleimide I inhibits the reaction [cypermethrin results in increased expression of FSHB mRNA]; cypermethrin results in increased expression of and results in increased secretion of FSHB protein; Egtazic Acid inhibits the reaction [cypermethrin results in increased expression of FSHB mRNA]; Egtazic Acid inhibits the reaction [cypermethrin results in increased secretion of FSHB protein]; Nimodipine inhibits the reaction [cypermethrin results in increased expression of FSHB mRNA]; Nimodipine inhibits the reaction [cypermethrin results in increased secretion of FSHB protein]
Vitamin E inhibits the reaction [cypermethrin results in decreased expression of FSHB protein]
CTD PMID:23447098, PMID:24759048, PMID:28731686, PMID:29149324 NCBI chr 3:98,088,321...98,092,131
Ensembl chr 3:98,088,324...98,092,131
JBrowse link
G Fshr follicle stimulating hormone receptor multiple interactions EXP [cypermethrin co-treated with Diethylhexyl Phthalate] results in decreased expression of FSHR mRNA CTD PMID:24641848 NCBI chr 6:12,796,383...12,997,817
Ensembl chr 6:12,796,383...12,997,817
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase multiple interactions
decreases activity
EXP [cypermethrin co-treated with propetamphos] results in decreased activity of G6PD protein
cypermethrin results in decreased activity of G6PD protein
CTD PMID:25926273 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926
JBrowse link
G Gabra1 gamma-aminobutyric acid type A receptor subunit alpha 1 multiple interactions
decreases expression
EXP cypermethrin promotes the reaction [cypermethrin results in decreased expression of GABRA1 mRNA]; cypermethrin promotes the reaction [cypermethrin results in decreased expression of GABRA1 protein]
cypermethrin results in decreased expression of GABRA1 mRNA; cypermethrin results in decreased expression of GABRA1 protein
CTD PMID:25288152 NCBI chr10:27,310,718...27,371,802
Ensembl chr10:27,310,725...27,366,665
JBrowse link
G Gabrg2 gamma-aminobutyric acid type A receptor subunit gamma 2 decreases expression ISO cypermethrin results in decreased expression of GABRG2 mRNA CTD PMID:24220872 NCBI chr10:27,090,913...27,179,786
Ensembl chr10:27,092,827...27,179,900
JBrowse link
G Gad1 glutamate decarboxylase 1 decreases expression EXP cypermethrin results in decreased expression of GAD1 mRNA; cypermethrin results in decreased expression of GAD1 protein CTD PMID:26115703 NCBI chr 3:56,861,440...56,902,139
Ensembl chr 3:56,861,396...56,902,157
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression EXP
ISO
cypermethrin results in increased expression of GADD45A mRNA CTD PMID:22528246, PMID:27704156 NCBI chr 4:97,782,512...97,784,814
Ensembl chr 4:97,782,512...97,784,842
JBrowse link
G Gap43 growth associated protein 43 increases expression ISO cypermethrin results in increased expression of GAP43 mRNA CTD PMID:32028016 NCBI chr11:58,624,198...58,717,916
Ensembl chr11:58,624,198...58,717,914
JBrowse link
G Gata2 GATA binding protein 2 decreases expression EXP cypermethrin results in decreased expression of GATA2 mRNA CTD PMID:22528246 NCBI chr 4:120,129,028...120,142,490
Ensembl chr 4:120,133,713...120,142,488
JBrowse link
G Gh1 growth hormone 1 decreases expression EXP cypermethrin results in decreased expression of GH1 protein CTD PMID:26115703 NCBI chr10:94,486,204...94,488,181
Ensembl chr10:94,486,205...94,488,180
JBrowse link
G Gjc2 gap junction protein, gamma 2 increases expression
multiple interactions
EXP cypermethrin results in increased expression of GJC2 protein modified form
Minocycline inhibits the reaction [cypermethrin results in increased expression of GJC2 protein modified form]
CTD PMID:21561882 NCBI chr10:45,526,740...45,535,520
Ensembl chr10:45,526,745...45,534,570
JBrowse link
G Glul glutamate-ammonia ligase decreases activity ISO cypermethrin results in decreased activity of GLUL protein CTD PMID:24649940 NCBI chr13:71,331,052...71,340,207
Ensembl chr13:71,331,052...71,340,229
JBrowse link
G Gnrh1 gonadotropin releasing hormone 1 affects secretion ISO cypermethrin affects the secretion of GNRH1 protein CTD PMID:28731686 NCBI chr15:44,441,856...44,446,064
Ensembl chr15:44,442,555...44,442,875
Ensembl chr15:44,442,555...44,442,875
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 multiple interactions
increases secretion
increases activity
decreases activity
ISO
EXP
[cypermethrin co-treated with Chlorpyrifos] results in increased expression of GOT1 protein; Plant Extracts inhibits the reaction [[cypermethrin co-treated with Chlorpyrifos] results in increased expression of GOT1 protein]
cypermethrin results in increased secretion of GOT1 protein
Phenobarbital inhibits the reaction [cypermethrin results in increased secretion of GOT1 protein]; Proadifen promotes the reaction [cypermethrin results in increased secretion of GOT1 protein]
cypermethrin results in increased activity of GOT1 protein
cypermethrin results in decreased activity of GOT1 protein
CTD PMID:2466999, PMID:11428908, PMID:15365239, PMID:15991261 NCBI chr 1:263,246,248...263,269,762
Ensembl chr 1:263,246,248...263,269,762
JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 increases expression
multiple interactions
EXP cypermethrin results in increased expression of GOT2
Sesame Oil inhibits the reaction [cypermethrin results in increased expression of GOT2]
CTD PMID:25816392 NCBI chr19:9,587,637...9,613,323
Ensembl chr19:9,587,653...9,613,340
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions
increases expression
increases activity
increases secretion
ISO
EXP
[cypermethrin co-treated with Chlorpyrifos] results in increased expression of GPT protein; Plant Extracts inhibits the reaction [[cypermethrin co-treated with Chlorpyrifos] results in increased expression of GPT protein]
cypermethrin results in increased expression of GPT
Phenobarbital inhibits the reaction [cypermethrin results in increased secretion of GPT protein]; Proadifen promotes the reaction [cypermethrin results in increased secretion of GPT protein]; Sesame Oil inhibits the reaction [cypermethrin results in increased expression of GPT]
cypermethrin results in increased activity of GPT protein
CTD PMID:11428908, PMID:15365239, PMID:15991261, PMID:25816392 NCBI chr 7:117,759,083...117,761,932
Ensembl chr 7:117,759,083...117,761,931
JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions
affects expression
increases expression
ISO [cypermethrin co-treated with Chlorpyrifos] results in decreased activity of GPX1 protein; Plant Extracts inhibits the reaction [[cypermethrin co-treated with Chlorpyrifos] results in decreased activity of GPX1 protein]
cypermethrin affects the expression of GPX1 mRNA
cypermethrin results in increased expression of GPX1 mRNA
CTD PMID:15991261, PMID:21397294, PMID:32214279 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G Gpx2 glutathione peroxidase 2 increases expression ISO cypermethrin results in increased expression of GPX2 mRNA CTD PMID:21397294 NCBI chr 6:99,839,960...99,843,245
Ensembl chr 6:99,839,960...99,843,245
JBrowse link
G Gpx4 glutathione peroxidase 4 increases expression ISO cypermethrin results in increased expression of GPX4 mRNA CTD PMID:21142847, PMID:32214279 NCBI chr 7:12,516,357...12,519,154
Ensembl chr 7:12,516,352...12,519,154
JBrowse link
G Grb2 growth factor receptor bound protein 2 decreases expression ISO cypermethrin results in decreased expression of GRB2 mRNA CTD PMID:27704156 NCBI chr10:104,193,953...104,263,071
Ensembl chr10:104,193,955...104,263,071
JBrowse link
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 affects expression ISO cypermethrin affects the expression of GRIA1 protein CTD PMID:26143737 NCBI chr10:42,441,723...42,760,200
Ensembl chr10:42,614,713...42,760,200
JBrowse link
G Grp gastrin releasing peptide increases expression ISO cypermethrin results in increased expression of GRP mRNA CTD PMID:29020013 NCBI chr18:61,563,458...61,576,818
Ensembl chr18:61,563,053...61,576,818
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions
increases expression
ISO [cypermethrin co-treated with Chlorpyrifos] results in decreased activity of GSR protein; Plant Extracts inhibits the reaction [[cypermethrin co-treated with Chlorpyrifos] results in decreased activity of GSR protein]
cypermethrin results in increased expression of GSR mRNA
CTD PMID:15991261, PMID:21142847 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Gsta2 glutathione S-transferase alpha 2 increases expression ISO cypermethrin results in increased expression of GSTA1; cypermethrin results in increased expression of GSTA1 mRNA CTD PMID:32214279 NCBI chr 8:85,640,081...85,645,621 JBrowse link
G Gsta4 glutathione S-transferase alpha 4 increases expression EXP cypermethrin results in increased expression of GSTA4 mRNA CTD PMID:20815782 NCBI chr 8:85,497,557...85,514,732
Ensembl chr 8:85,497,557...85,518,879
JBrowse link
G Gsta6 glutathione S-transferase alpha 6 increases expression ISO cypermethrin results in increased expression of GSTA1; cypermethrin results in increased expression of GSTA1 mRNA CTD PMID:32214279 NCBI chr 9:27,475,273...27,533,939
Ensembl chr 9:27,475,273...27,511,176
JBrowse link
G Gstk1 glutathione S-transferase kappa 1 increases expression ISO cypermethrin results in increased expression of GSTK1 mRNA CTD PMID:21142847 NCBI chr 4:71,621,777...71,626,096
Ensembl chr 4:71,621,729...71,626,107
JBrowse link
G Gstp1 glutathione S-transferase pi 1 decreases expression EXP cypermethrin results in decreased expression of GSTP1 mRNA CTD PMID:22528246 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Gtf2h1 general transcription factor IIH subunit 1 increases expression ISO cypermethrin results in increased expression of GTF2H1 mRNA CTD PMID:21142847 NCBI chr 1:102,849,618...102,877,939
Ensembl chr 1:102,849,889...102,877,944
JBrowse link
G H1f2 H1.2 linker histone, cluster member decreases expression ISO cypermethrin results in decreased expression of H1F2 mRNA CTD PMID:29020013 NCBI chr17:43,638,938...43,640,445
Ensembl chr17:43,639,749...43,640,387
JBrowse link
G Hba-a2 hemoglobin alpha, adult chain 2 decreases expression ISO cypermethrin results in decreased expression of HBA-A2 mRNA CTD PMID:29020013 NCBI chr10:15,589,364...15,590,207
Ensembl chr10:15,589,364...15,590,220
JBrowse link
G Hbegf heparin-binding EGF-like growth factor multiple interactions
decreases response to substance
decreases expression
EXP cypermethrin results in decreased expression of and results in decreased secretion of HBEGF protein; HBEGF protein inhibits the reaction [cypermethrin results in decreased expression of BCL2 protein]; HBEGF protein inhibits the reaction [cypermethrin results in decreased expression of BCL2L1 protein]; HBEGF protein inhibits the reaction [cypermethrin results in increased expression of BAX protein]
HBEGF protein results in decreased susceptibility to cypermethrin
cypermethrin results in decreased expression of HBEGF mRNA
CTD PMID:22048644 NCBI chr18:29,330,302...29,340,185
Ensembl chr18:29,329,764...29,340,403
JBrowse link
G Hist1h2bq histone cluster 1 H2B family member Q decreases expression ISO cypermethrin results in decreased expression of H2BC7 mRNA CTD PMID:29020013 NCBI chr17:43,679,925...43,689,311
Ensembl chr17:43,679,925...43,689,311
JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 decreases expression ISO cypermethrin results in decreased expression of HMGCS1 mRNA CTD PMID:21397294 NCBI chr 2:52,427,351...52,445,082
Ensembl chr 2:52,431,601...52,445,055
JBrowse link
G Hmox1 heme oxygenase 1 affects expression
decreases expression
multiple interactions
increases expression
EXP
ISO
cypermethrin affects the expression of HMOX1
cypermethrin results in decreased expression of HMOX1 mRNA; cypermethrin results in decreased expression of HMOX1 protein
Acetylcysteine inhibits the reaction [cypermethrin results in increased expression of HMOX1 mRNA]; Sesame Oil affects the reaction [cypermethrin affects the expression of HMOX1]
CTD PMID:23900960, PMID:25816392, PMID:31907151 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hoxa10 homeobox A10 decreases expression ISO cypermethrin results in decreased expression of HOXA10 mRNA; cypermethrin results in decreased expression of HOXA10 protein CTD PMID:29253587 NCBI chr 4:82,285,940...82,295,892
Ensembl chr 4:82,285,528...82,295,470
JBrowse link
G Hpdl 4-hydroxyphenylpyruvate dioxygenase-like increases expression ISO cypermethrin results in increased expression of HPDL mRNA CTD PMID:29020013 NCBI chr 5:135,675,826...135,677,432
Ensembl chr 5:135,675,832...135,677,432
JBrowse link
G Hrk harakiri, BCL2 interacting protein decreases expression ISO cypermethrin results in decreased expression of HRK mRNA CTD PMID:29020013 NCBI chr12:44,008,879...44,029,211 JBrowse link
G Hsd17b3 hydroxysteroid (17-beta) dehydrogenase 3 decreases expression ISO cypermethrin results in decreased expression of HSD17B3 mRNA; cypermethrin results in decreased