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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:endothelin receptor antagonist
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Accession:CHEBI:51451 term browser browse the term
Definition:A hormone antagonist that blocks endothelin receptors.
Synonyms:related_synonym: ERA


show annotations for term's descendants           Sort by:
losartan term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGT angiotensinogen affects activity EXP Losartan affects the activity of AGT protein CTD PMID:21127344 NCBI chr14:59,643,030...59,656,835
Ensembl chr14:59,643,292...59,656,833 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 5066
    role 5030
      biological role 5030
        pharmacological role 622
          antagonist 222
            hormone antagonist 23
              endothelin receptor antagonist 1
                ACT-132577 + 0
                PD123319 0
                bosentan + 0
                endothelin A receptor antagonist + 0
                enrasentan 0
                losartan + 1
                macitentan 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 5066
    role 5030
      application 869
        pharmaceutical 719
          drug 719
            receptor modulator 198
              hormone receptor modulator 191
                hormone antagonist 23
                  endothelin receptor antagonist 1
                    ACT-132577 + 0
                    PD123319 0
                    bosentan + 0
                    endothelin A receptor antagonist + 0
                    enrasentan 0
                    losartan + 1
                    macitentan 0
paths to the root