Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:muscle relaxant
go back to main search page
Accession:CHEBI:51371 term browser browse the term
Definition:A drug used to produce muscle relaxation (excepting neuromuscular blocking agents). Its primary clinical and therapeutic use is the treatment of muscle spasm and immobility associated with strains, sprains, and injuries of the back and, to a lesser degree, injuries to the neck. Also used for the treatment of a variety of clinical conditions that have in common only the presence of skeletal muscle hyperactivity, for example, the muscle spasms that can occur in multiple sclerosis.
Synonyms:related_synonym: muscle relaxants


show annotations for term's descendants           Sort by:
 
(S)-glaucine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A increases activity ISO glaucine results in increased activity of ABCB1 protein CTD PMID:23273999 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
1-hydroxymidazolam term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases chemical synthesis
increases glucuronidation
multiple interactions
increases abundance
ISO CYP3A4 protein results in increased chemical synthesis of 1-hydroxymethylmidazolam
CYP3A4 protein results in increased glucuronidation of 1-hydroxymethylmidazolam
[[3-hydroxyflavone results in increased activity of CYP3A4 protein] which results in increased metabolism of Midazolam] which results in increased chemical synthesis of 1-hydroxymethylmidazolam; [[5-hydroxyflavone results in increased activity of CYP3A4 protein] which results in increased metabolism of Midazolam] which results in increased chemical synthesis of 1-hydroxymethylmidazolam; [[6-hydroxyflavone results in increased activity of CYP3A4 protein] which results in increased metabolism of Midazolam] which results in increased chemical synthesis of 1-hydroxymethylmidazolam; [[6-methylflavone results in increased activity of CYP3A4 protein] which results in increased metabolism of Midazolam] which results in increased chemical synthesis of 1-hydroxymethylmidazolam; [[7-hydroxyflavone results in increased activity of CYP3A4 protein] which results in increased metabolism of Midazolam] which results in increased chemical synthesis of 1-hydroxymethylmidazolam; [[alpha-naphthoflavone results in increased activity of CYP3A4 protein] which results in increased metabolism of Midazolam] which results in increased chemical synthesis of 1-hydroxymethylmidazolam; [[artemetin results in increased activity of CYP3A4 protein] which results in increased metabolism of Midazolam] which results in increased chemical synthesis of 1-hydroxymethylmidazolam; [[beta-Naphthoflavone results in increased activity of CYP3A4 protein] which results in increased metabolism of Midazolam] which results in increased chemical synthesis of 1-hydroxymethylmidazolam; [[chrysin results in increased activity of CYP3A4 protein] which results in increased metabolism of Midazolam] which results in increased chemical synthesis of 1-hydroxymethylmidazolam; [[eupatilin results in increased activity of CYP3A4 protein] which results in increased metabolism of Midazolam] which results in increased chemical synthesis of 1-hydroxymethylmidazolam; [[flavone results in increased activity of CYP3A4 protein] which results in increased metabolism of Midazolam] which results in increased chemical synthesis of 1-hydroxymethylmidazolam; [[galangin results in increased activity of CYP3A4 protein] which results in increased metabolism of Midazolam] which results in increased chemical synthesis of 1-hydroxymethylmidazolam; [[nobiletin results in increased activity of CYP3A4 protein] which results in increased metabolism of Midazolam] which results in increased chemical synthesis of 1-hydroxymethylmidazolam; [[sinensetin analog results in increased activity of CYP3A4 protein] which results in increased metabolism of Midazolam] which results in increased chemical synthesis of 1-hydroxymethylmidazolam; [[sinensetin results in increased activity of CYP3A4 protein] which results in increased metabolism of Midazolam] which results in increased chemical synthesis of 1-hydroxymethylmidazolam; [[tangeretin results in increased activity of CYP3A4 protein] which results in increased metabolism of Midazolam] which results in increased chemical synthesis of 1-hydroxymethylmidazolam; [CYP3A4 protein results in increased glucuronidation of 1-hydroxymethylmidazolam] which results in increased abundance of 1-hydroxymethylmidazolam glucuronide; [CYP3A4 protein results in increased hydroxylation of Midazolam] which results in increased abundance of 1-hydroxymethylmidazolam; [CYP3A4 protein results in increased hydroxylation of Midazolam] which results in increased chemical synthesis of 1-hydroxymethylmidazolam; [CYP3A4 protein results in increased oxidation of Midazolam] which results in increased chemical synthesis of 1-hydroxymethylmidazolam; [Ketoconazole results in decreased activity of CYP3A4 protein] which results in decreased chemical synthesis of 1-hydroxymethylmidazolam; [L 754394 results in decreased activity of CYP3A4 protein] which results in decreased chemical synthesis of 1-hydroxymethylmidazolam; acacetin promotes the reaction [[CYP3A4 protein results in increased oxidation of Midazolam] which results in increased chemical synthesis of 1-hydroxymethylmidazolam]; Apigenin promotes the reaction [[CYP3A4 protein results in increased oxidation of Midazolam] which results in increased chemical synthesis of 1-hydroxymethylmidazolam]; CYP3A4 protein inhibits the reaction [Rifampin results in decreased chemical synthesis of 1-hydroxymethylmidazolam]; diosmetin inhibits the reaction [CYP3A4 protein results in increased chemical synthesis of 1-hydroxymethylmidazolam]; flavanone promotes the reaction [[CYP3A4 protein results in increased oxidation of Midazolam] which results in increased chemical synthesis of 1-hydroxymethylmidazolam]; flavone promotes the reaction [[CYP3A4 protein results in increased oxidation of Midazolam] which results in increased chemical synthesis of 1-hydroxymethylmidazolam]; galangin promotes the reaction [[CYP3A4 protein results in increased oxidation of Midazolam] which results in increased chemical synthesis of 1-hydroxymethylmidazolam]; Ketoconazole inhibits the reaction [CYP3A4 protein results in increased abundance of 1-hydroxymethylmidazolam]; Ketoconazole inhibits the reaction [CYP3A4 protein results in increased chemical synthesis of 1-hydroxymethylmidazolam]; Luteolin inhibits the reaction [CYP3A4 protein results in increased chemical synthesis of 1-hydroxymethylmidazolam]; Rifampin inhibits the reaction [CYP3A4 protein results in increased chemical synthesis of 1-hydroxymethylmidazolam]; Rifampin promotes the reaction [CYP3A4 protein results in increased chemical synthesis of 1-hydroxymethylmidazolam]; Troleandomycin inhibits the reaction [CYP3A4 protein results in increased chemical synthesis of 1-hydroxymethylmidazolam]; Verapamil inhibits the reaction [CYP3A4 protein results in increased chemical synthesis of 1-hydroxymethylmidazolam]
CTD PMID:10997946 PMID:12401345 PMID:12695342 PMID:18191104 PMID:20233841 More... NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 increases chemical synthesis ISO CYP3A5 protein results in increased chemical synthesis of 1-hydroxymethylmidazolam CTD PMID:18191104 PMID:26958860 NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422
JBrowse link
G Tspo translocator protein affects binding EXP 1-hydroxymethylmidazolam binds to TSPO protein; 1-hydroxymethylmidazolam metabolite binds to TSPO protein CTD PMID:7603229 NCBI chr 7:114,720,188...114,730,450
Ensembl chr 7:114,720,188...114,730,450
JBrowse link
1-hydroxymidazolam beta-D-glucuronide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions ISO [CYP3A4 protein results in increased glucuronidation of 1-hydroxymethylmidazolam] which results in increased abundance of 1-hydroxymethylmidazolam glucuronide CTD PMID:27485346 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
3-hydroxyquinine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 affects chemical synthesis ISO CYP3A4 protein affects the chemical synthesis of 3-hydroxyquinidine CTD PMID:15896247 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
4-hydroxymidazolam term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases chemical synthesis
multiple interactions
ISO CYP3A4 protein results in increased chemical synthesis of 4-hydroxymidazolam
[CYP3A4 protein results in increased hydroxylation of Midazolam] which results in increased abundance of 4-hydroxymidazolam; [CYP3A4 protein results in increased oxidation of Midazolam] which results in increased chemical synthesis of 4-hydroxymidazolam; acacetin inhibits the reaction [[CYP3A4 protein results in increased oxidation of Midazolam] which results in increased chemical synthesis of 4-hydroxymidazolam]; Apigenin inhibits the reaction [[CYP3A4 protein results in increased oxidation of Midazolam] which results in increased chemical synthesis of 4-hydroxymidazolam]; CYP3A4 protein inhibits the reaction [Rifampin results in decreased chemical synthesis of 4-hydroxymidazolam]; diosmetin inhibits the reaction [CYP3A4 protein results in increased chemical synthesis of 4-hydroxymidazolam]; flavanone inhibits the reaction [[CYP3A4 protein results in increased oxidation of Midazolam] which results in increased chemical synthesis of 4-hydroxymidazolam]; flavone inhibits the reaction [[CYP3A4 protein results in increased oxidation of Midazolam] which results in increased chemical synthesis of 4-hydroxymidazolam]; galangin inhibits the reaction [[CYP3A4 protein results in increased oxidation of Midazolam] which results in increased chemical synthesis of 4-hydroxymidazolam]; Ketoconazole inhibits the reaction [CYP3A4 protein results in increased chemical synthesis of 4-hydroxymidazolam]; Luteolin inhibits the reaction [CYP3A4 protein results in increased chemical synthesis of 4-hydroxymidazolam]; Rifampin inhibits the reaction [CYP3A4 protein results in increased chemical synthesis of 4-hydroxymidazolam]; Troleandomycin inhibits the reaction [CYP3A4 protein results in increased chemical synthesis of 4-hydroxymidazolam]
CTD PMID:12695342 PMID:18191104 PMID:21053930 PMID:27485346 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 increases chemical synthesis
multiple interactions
ISO CYP3A5 protein results in increased chemical synthesis of 4-hydroxymidazolam
diosmetin inhibits the reaction [CYP3A5 protein results in increased chemical synthesis of 4-hydroxymidazolam]; Luteolin inhibits the reaction [CYP3A5 protein results in increased chemical synthesis of 4-hydroxymidazolam]
CTD PMID:18191104 NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422
JBrowse link
8-bromo-3',5'-cyclic GMP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arhgef17 Rho guanine nucleotide exchange factor 17 multiple interactions ISO [8-bromocyclic GMP co-treated with PRKG1 protein co-treated with ARHGEF17 protein] results in increased activity of SRF protein CTD PMID:23195829 Ensembl chr 1:155,233,168...155,290,498 JBrowse link
G Casp3 caspase 3 multiple interactions ISO 8-bromocyclic GMP inhibits the reaction [TNF protein results in increased activity of CASP3 protein]; KT 5823 inhibits the reaction [8-bromocyclic GMP inhibits the reaction [TNF protein results in increased activity of CASP3 protein]] CTD PMID:9388267 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Cox4i1 cytochrome c oxidase subunit 4i1 increases expression
multiple interactions
ISO 8-bromocyclic GMP results in increased expression of COX4I1 protein
tin protoporphyrin IX inhibits the reaction [8-bromocyclic GMP results in increased expression of COX4I1 protein]
CTD PMID:24041027 NCBI chr19:48,721,680...48,727,920
Ensembl chr19:48,721,199...48,727,921
JBrowse link
G Dusp10 dual specificity phosphatase 10 increases expression ISO 8-bromocyclic GMP results in increased expression of DUSP10 mRNA; 8-bromocyclic GMP results in increased expression of DUSP10 protein CTD PMID:29165873 NCBI chr13:95,613,716...95,651,716
Ensembl chr13:95,614,292...95,651,716
JBrowse link
G Edn1 endothelin 1 multiple interactions EXP
ISO
8-bromocyclic GMP inhibits the reaction [[EDN1 protein binds to and results in increased activity of EDNRB protein] which results in decreased activity of TH protein]
8-bromocyclic GMP inhibits the reaction [cobaltous chloride results in increased expression of EDN1 mRNA]; 8-bromocyclic GMP inhibits the reaction [cobaltous chloride results in increased expression of EDN1 protein]
CTD PMID:16023617 PMID:29165873 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Edn3 endothelin 3 multiple interactions EXP 8-bromocyclic GMP inhibits the reaction [[EDN3 protein binds to and results in increased activity of EDNRB protein] which results in decreased activity of TH protein] CTD PMID:16023617 NCBI chr 3:163,562,307...163,586,636
Ensembl chr 3:163,562,520...163,585,093
JBrowse link
G Ednrb endothelin receptor type B multiple interactions EXP 8-bromocyclic GMP inhibits the reaction [[EDN1 protein binds to and results in increased activity of EDNRB protein] which results in decreased activity of TH protein]; 8-bromocyclic GMP inhibits the reaction [[EDN3 protein binds to and results in increased activity of EDNRB protein] which results in decreased activity of TH protein] CTD PMID:16023617 NCBI chr15:80,640,839...80,672,115
Ensembl chr15:80,643,043...80,672,115
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha multiple interactions ISO 8-bromocyclic GMP inhibits the reaction [cobaltous chloride results in increased expression of HIF1A mRNA]; 8-bromocyclic GMP inhibits the reaction [cobaltous chloride results in increased expression of HIF1A protein] CTD PMID:29165873 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO 8-bromocyclic GMP results in increased expression of HMOX1 mRNA; 8-bromocyclic GMP results in increased expression of HMOX1 protein CTD PMID:24041027 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO 8-bromocyclic GMP promotes the reaction [IL1B protein results in increased abundance of Nitrites]; Dipyridamole promotes the reaction [8-bromocyclic GMP promotes the reaction [IL1B protein results in increased abundance of Nitrites]] CTD PMID:8904084 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il4 interleukin 4 increases expression
multiple interactions
ISO 8-bromocyclic GMP results in increased expression of IL4 mRNA
Cyclosporine inhibits the reaction [8-bromocyclic GMP results in increased expression of IL4 mRNA]
CTD PMID:16533816 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Mapk1 mitogen activated protein kinase 1 decreases phosphorylation ISO 8-bromocyclic GMP results in decreased phosphorylation of MAPK1 protein CTD PMID:17828804 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 decreases phosphorylation ISO 8-bromocyclic GMP results in decreased phosphorylation of MAPK3 protein CTD PMID:17828804 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases phosphorylation ISO 8-bromocyclic GMP results in decreased phosphorylation of MYC protein CTD PMID:17828804 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Ndufb8 NADH:ubiquinone oxidoreductase subunit B8 increases expression
multiple interactions
ISO 8-bromocyclic GMP results in increased expression of NDUFB8 protein
tin protoporphyrin IX inhibits the reaction [8-bromocyclic GMP results in increased expression of NDUFB8 protein]
CTD PMID:24041027 NCBI chr 1:243,408,659...243,413,701
Ensembl chr 1:243,408,619...243,413,817
JBrowse link
G Nfatc1 nuclear factor of activated T-cells 1 affects localization ISO 8-bromocyclic GMP affects the localization of NFATC1 protein CTD PMID:16533816 NCBI chr18:74,046,421...74,156,041
Ensembl chr18:74,046,904...74,156,028
JBrowse link
G Nrf1 nuclear respiratory factor 1 increases expression
multiple interactions
ISO 8-bromocyclic GMP results in increased expression of NRF1 mRNA
tin protoporphyrin IX inhibits the reaction [8-bromocyclic GMP results in increased expression of NRF1 mRNA]
CTD PMID:24041027 NCBI chr 4:58,664,932...58,772,328
Ensembl chr 4:58,664,957...58,825,328
JBrowse link
G Pde5a phosphodiesterase 5A multiple interactions ISO [1-Methyl-3-isobutylxanthine co-treated with 8-bromocyclic GMP] results in increased expression of PDE5A protein; [1-Methyl-3-isobutylxanthine co-treated with 8-bromocyclic GMP] results in increased expression of PDE5A protein modified form CTD PMID:20613715 NCBI chr 2:210,858,515...211,003,480
Ensembl chr 2:210,858,063...210,999,701
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha increases expression
multiple interactions
ISO 8-bromocyclic GMP results in increased expression of PPARGC1A mRNA
tin protoporphyrin IX inhibits the reaction [8-bromocyclic GMP results in increased expression of PPARGC1A mRNA]
CTD PMID:24041027 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
JBrowse link
G Prkg1 protein kinase cGMP-dependent 1 increases expression
multiple interactions
EXP
ISO
8-bromocyclic GMP results in increased expression of PRKG1 protein
[8-bromocyclic GMP co-treated with PRKG1 protein co-treated with ARHGEF17 protein] results in increased activity of SRF protein
CTD PMID:12620371 PMID:23195829 NCBI chr 1:228,409,883...229,638,794 JBrowse link
G Scnn1b sodium channel epithelial 1 subunit beta multiple interactions ISO [1-Methyl-3-isobutylxanthine co-treated with 8-bromocyclic GMP] results in increased expression of SCNN1B protein CTD PMID:20613715 NCBI chr 1:176,430,063...176,484,451
Ensembl chr 1:176,430,103...176,484,451
JBrowse link
G Sod2 superoxide dismutase 2 increases expression EXP 8-bromocyclic GMP results in increased expression of SOD2 mRNA; 8-bromocyclic GMP results in increased expression of SOD2 protein CTD PMID:14996425 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Spp1 secreted phosphoprotein 1 multiple interactions EXP 8-bromocyclic GMP inhibits the reaction [Glucose results in increased secretion of SPP1 protein]; Dinitrochlorobenzene inhibits the reaction [8-bromocyclic GMP inhibits the reaction [Glucose results in increased secretion of SPP1 protein]]; KT 5823 inhibits the reaction [8-bromocyclic GMP inhibits the reaction [Glucose results in increased secretion of SPP1 protein]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [8-bromocyclic GMP inhibits the reaction [Glucose results in increased secretion of SPP1 protein]] CTD PMID:20453393 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162
JBrowse link
G Srf serum response factor multiple interactions ISO [8-bromocyclic GMP co-treated with PRKG1 protein co-treated with ARHGEF17 protein] results in increased activity of SRF protein CTD PMID:23195829 NCBI chr 9:14,426,453...14,435,734
Ensembl chr 9:14,426,472...14,435,733
JBrowse link
G Tfam transcription factor A, mitochondrial increases expression
multiple interactions
ISO 8-bromocyclic GMP results in increased expression of TFAM mRNA
tin protoporphyrin IX inhibits the reaction [8-bromocyclic GMP results in increased expression of TFAM mRNA]
CTD PMID:24041027 NCBI chr20:17,356,243...17,368,293
Ensembl chr20:17,356,197...17,368,292
JBrowse link
G Th tyrosine hydroxylase multiple interactions EXP 8-bromocyclic GMP inhibits the reaction [[EDN1 protein binds to and results in increased activity of EDNRB protein] which results in decreased activity of TH protein]; 8-bromocyclic GMP inhibits the reaction [[EDN3 protein binds to and results in increased activity of EDNRB protein] which results in decreased activity of TH protein] CTD PMID:16023617 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO 8-bromocyclic GMP inhibits the reaction [TNF protein results in increased activity of CASP3 protein]; KT 5823 inhibits the reaction [8-bromocyclic GMP inhibits the reaction [TNF protein results in increased activity of CASP3 protein]] CTD PMID:9388267 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tp53 tumor protein p53 increases expression EXP 8-bromocyclic GMP results in increased expression of TP53 protein CTD PMID:9888876 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Trpc6 transient receptor potential cation channel, subfamily C, member 6 multiple interactions
increases phosphorylation
EXP
ISO
8-bromocyclic GMP inhibits the reaction [1-oleoyl-2-acetylglycerol results in increased activity of TRPC6 protein]
8-bromocyclic GMP results in increased phosphorylation of TRPC6 protein
KT 5823 inhibits the reaction [8-bromocyclic GMP results in increased phosphorylation of TRPC6 protein]
CTD PMID:20177073 NCBI chr 8:5,759,387...5,864,000
Ensembl chr 8:5,758,935...5,828,092
JBrowse link
G Txn1 thioredoxin 1 multiple interactions EXP 8-bromocyclic GMP inhibits the reaction [Glucose results in decreased expression of TXN1 protein] CTD PMID:20453393 NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629
JBrowse link
G Uqcrc1 ubiquinol-cytochrome c reductase core protein 1 multiple interactions
increases expression
ISO tin protoporphyrin IX inhibits the reaction [8-bromocyclic GMP results in increased expression of UQCRC1 protein] CTD PMID:24041027 NCBI chr 8:109,589,735...109,601,481
Ensembl chr 8:109,589,706...109,601,480
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 decreases expression ISO 8-bromocyclic GMP results in decreased expression of VCAM1 protein CTD PMID:17828804 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
JBrowse link
G Vegfa vascular endothelial growth factor A decreases expression ISO 8-bromocyclic GMP results in decreased expression of VEGFA protein CTD PMID:17828804 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
alcuronium term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrm4 cholinergic receptor, muscarinic 4 multiple interactions
affects binding
ISO WIN 62577 inhibits the reaction [Alcuronium binds to CHRM4 protein] CTD PMID:16709648 NCBI chr 3:77,893,425...77,901,166
Ensembl chr 3:77,893,425...77,901,159
JBrowse link
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit multiple interactions ISO Alcuronium inhibits the reaction [epibatidine binds to [CHRNA4 protein binds to CHRNB2 protein]]; Alcuronium results in decreased activity of [CHRNA4 protein binds to CHRNB2 protein] CTD PMID:14645658 NCBI chr 3:168,136,246...168,157,839
Ensembl chr 3:168,136,266...168,156,957
JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit multiple interactions ISO Alcuronium inhibits the reaction [epibatidine binds to [CHRNA4 protein binds to CHRNB2 protein]]; Alcuronium results in decreased activity of [CHRNA4 protein binds to CHRNB2 protein] CTD PMID:14645658 NCBI chr 2:175,181,402...175,189,619
Ensembl chr 2:175,181,402...175,189,619
JBrowse link
alprazolam term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Capn1 calpain 1 multiple interactions ISO [Caffeine co-treated with Alprazolam] promotes the reaction [Calcium results in increased activity of CAPN1 protein] CTD PMID:19490937 NCBI chr 1:203,275,912...203,300,848
Ensembl chr 1:203,277,344...203,300,177
JBrowse link
G Casp3 caspase 3 multiple interactions ISO [Caffeine co-treated with Alprazolam] results in increased cleavage of CASP3 protein CTD PMID:19490937 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Ctsb cathepsin B multiple interactions ISO [Caffeine co-treated with Alprazolam] results in increased secretion of CTSB protein CTD PMID:19490937 NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions
affects metabolic processing
ISO CYP3A4 protein binds to and affects the metabolism of Alprazolam
CYP3A4 protein affects the metabolism of Alprazolam
CTD PMID:12196913 PMID:15856409 PMID:16042670 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 affects metabolic processing EXP CYP3A23-3A1 protein affects the metabolism of Alprazolam CTD PMID:12196913 NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 increases hydroxylation ISO CYP3A5 protein results in increased hydroxylation of Alprazolam CTD PMID:15903124 NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422
JBrowse link
G Il2 interleukin 2 decreases expression ISO Alprazolam results in decreased expression of IL2 protein CTD PMID:1624223 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
JBrowse link
G Lhb luteinizing hormone subunit beta increases secretion ISO Alprazolam results in increased secretion of LHB protein CTD PMID:7883836 NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972
Ensembl chr 1:95,900,984...95,901,972
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO [Caffeine co-treated with Alprazolam] results in increased activity of PARP1 protein CTD PMID:19490937 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Plcb1 phospholipase C beta 1 decreases expression EXP Alprazolam results in decreased expression of PLCB1 mRNA; Alprazolam results in decreased expression of PLCB1 protein CTD PMID:12527476 NCBI chr 3:122,059,968...122,772,896
Ensembl chr 3:122,060,031...122,772,869
JBrowse link
G Ppia peptidylprolyl isomerase A increases hydroxylation ISO PPIA protein results in increased hydroxylation of Alprazolam CTD PMID:15806426 NCBI chr14:81,279,292...81,282,960
Ensembl chr14:81,275,091...81,299,601
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Alprazolam inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268
JBrowse link
G Trh thyrotropin releasing hormone multiple interactions EXP Alprazolam inhibits the reaction [TRH protein modified form binds to TRHR protein] CTD PMID:2845442 NCBI chr 4:124,742,111...124,777,094
Ensembl chr 4:124,742,111...124,744,637
JBrowse link
G Trhr thyrotropin releasing hormone receptor multiple interactions EXP Alprazolam inhibits the reaction [TRH protein modified form binds to TRHR protein] CTD PMID:2845442 NCBI chr 7:75,348,672...75,393,310
Ensembl chr 7:75,348,672...75,393,309
JBrowse link
alverine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Htr1a 5-hydroxytryptamine receptor 1A affects binding EXP alverine binds to HTR1A protein CTD PMID:11697552 NCBI chr 2:36,694,174...36,695,442
Ensembl chr 2:36,694,174...36,695,442
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO alverine results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008
JBrowse link
aminophylline term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh18a1 aldehyde dehydrogenase 18 family, member A1 increases expression ISO Aminophylline results in increased expression of ALDH18A1 mRNA CTD PMID:29901742 NCBI chr 1:239,375,657...239,407,967
Ensembl chr 1:239,375,669...239,407,890
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO [Aminophylline co-treated with gemcitabine] results in decreased expression of BCL2 protein CTD PMID:15645133 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Cat catalase multiple interactions ISO [Aminophylline co-treated with Photosensitizing Agents] promotes the reaction [Benzo(a)pyrene results in increased expression of CAT protein] CTD PMID:30776357 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Gcg glucagon increases secretion EXP Aminophylline results in increased secretion of GCG protein CTD PMID:1248788 NCBI chr 3:47,113,914...47,122,929
Ensembl chr 3:47,113,914...47,122,929
JBrowse link
G Hrh1 histamine receptor H 1 multiple interactions ISO [Astemizole binds to and results in decreased activity of HRH1 protein] which affects the susceptibility to Aminophylline CTD PMID:16129921 NCBI chr 4:147,564,781...147,649,353
Ensembl chr 4:147,645,995...147,647,455
JBrowse link
atracurium term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrna3 cholinergic receptor nicotinic alpha 3 subunit multiple interactions ISO Atracurium inhibits the reaction [Acetylcholine results in increased activity of [CHRNA3 protein binds to CHRNB2 protein]]; Atracurium inhibits the reaction [Acetylcholine results in increased activity of [CHRNA3 protein binds to CHRNB4 protein]] CTD PMID:16931985 NCBI chr 8:55,401,981...55,415,012
Ensembl chr 8:55,401,702...55,415,165
JBrowse link
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit multiple interactions ISO Atracurium inhibits the reaction [Acetylcholine results in increased activity of [CHRNA4 protein binds to CHRNB2 protein]] CTD PMID:16931985 NCBI chr 3:168,136,246...168,157,839
Ensembl chr 3:168,136,266...168,156,957
JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit multiple interactions ISO Atracurium inhibits the reaction [Acetylcholine results in increased activity of CHRNA7 protein] CTD PMID:16931985 NCBI chr 1:116,715,286...116,837,223
Ensembl chr 1:116,714,711...116,837,240
JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit multiple interactions ISO Atracurium inhibits the reaction [Acetylcholine results in increased activity of [CHRNA3 protein binds to CHRNB2 protein]]; Atracurium inhibits the reaction [Acetylcholine results in increased activity of [CHRNA4 protein binds to CHRNB2 protein]] CTD PMID:16931985 NCBI chr 2:175,181,402...175,189,619
Ensembl chr 2:175,181,402...175,189,619
JBrowse link
G Chrnb4 cholinergic receptor nicotinic beta 4 subunit multiple interactions ISO Atracurium inhibits the reaction [Acetylcholine results in increased activity of [CHRNA3 protein binds to CHRNB4 protein]] CTD PMID:16931985 NCBI chr 8:55,418,379...55,436,967
Ensembl chr 8:55,418,313...55,437,027
JBrowse link
G Hexb hexosaminidase subunit beta increases secretion ISO Atracurium results in increased secretion of HEXB protein CTD PMID:19758318 NCBI chr 2:28,483,997...28,504,165
Ensembl chr 2:28,484,012...28,504,223
JBrowse link
baclofen term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc4 ATP binding cassette subfamily C member 4 increases transport ISO ABCC4 protein results in increased transport of Baclofen CTD PMID:17939016 NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283
JBrowse link
G Cftr CF transmembrane conductance regulator multiple interactions ISO Baclofen promotes the reaction [Isoproterenol results in increased activity of CFTR protein] CTD PMID:15151902 NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions ISO Baclofen inhibits the reaction [Amphetamine affects the phosphorylation of CREB1 protein] CTD PMID:16983645 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Drd3 dopamine receptor D3 decreases expression EXP Baclofen results in decreased expression of DRD3 mRNA CTD PMID:7878047 NCBI chr11:56,879,689...56,931,901
Ensembl chr11:56,879,689...56,940,596
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO
EXP
Baclofen inhibits the reaction [Cocaine results in increased expression of FOS protein] CTD PMID:16710312 PMID:16930414 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Gabbr1 gamma-aminobutyric acid type B receptor subunit 1 increases response to substance ISO GABBR1 results in increased susceptibility to Baclofen CTD PMID:16990508 PMID:20138995 NCBI chr20:1,464,534...1,494,114
Ensembl chr20:1,464,534...1,493,994
JBrowse link
G Gabbr2 gamma-aminobutyric acid type B receptor subunit 2 increases response to substance ISO GABBR2 results in increased susceptibility to Baclofen CTD PMID:20138995 NCBI chr 5:60,947,517...61,288,104
Ensembl chr 5:60,947,526...61,288,104
JBrowse link
G Kcnj6 potassium inwardly-rectifying channel, subfamily J, member 6 increases response to substance ISO KCNJ6 results in increased susceptibility to Baclofen CTD PMID:12836919 NCBI chr11:34,061,705...34,309,128
Ensembl chr11:34,061,708...34,308,758
JBrowse link
G Maob monoamine oxidase B multiple interactions ISO Baclofen affects the reaction [MAOB gene mutant form results in decreased susceptibility to Amphetamine] CTD PMID:16983645 NCBI chr  X:5,907,327...6,010,996
Ensembl chr  X:5,907,266...6,011,003
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation
multiple interactions
EXP Baclofen results in increased phosphorylation of MAPK1 protein
CGP 56999A inhibits the reaction [Baclofen results in increased phosphorylation of MAPK1 protein]
CTD PMID:24668805 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation
EXP CGP 56999A inhibits the reaction [Baclofen results in increased phosphorylation of MAPK3 protein] CTD PMID:24668805 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Pdyn prodynorphin multiple interactions EXP Baclofen inhibits the reaction [Amphetamine results in increased expression of PDYN mRNA] CTD PMID:15033416 PMID:15592348 NCBI chr 3:116,900,990...116,913,334
Ensembl chr 3:116,900,992...116,913,334
JBrowse link
G Penk proenkephalin multiple interactions EXP Baclofen inhibits the reaction [Amphetamine results in increased expression of PENK mRNA] CTD PMID:15033416 PMID:15592348 NCBI chr 5:17,183,799...17,189,160
Ensembl chr 5:17,183,806...17,189,129
JBrowse link
G Ryr1 ryanodine receptor 1 multiple interactions ISO Baclofen inhibits the reaction [A 68930 results in increased expression of RYR1 protein]; Baclofen inhibits the reaction [SK&F 82958 results in increased expression of RYR1 protein] CTD PMID:22504960 NCBI chr 1:84,292,578...84,423,799
Ensembl chr 1:84,292,578...84,423,812
JBrowse link
G Ryr2 ryanodine receptor 2 multiple interactions ISO Baclofen inhibits the reaction [A 68930 results in increased expression of RYR2 protein]; Baclofen inhibits the reaction [SK&F 82958 results in increased expression of RYR2 protein] CTD PMID:22504960 NCBI chr17:58,389,925...58,975,641
Ensembl chr17:58,389,925...58,975,142
JBrowse link
G Scg2 secretogranin II multiple interactions EXP Baclofen inhibits the reaction [Amphetamine results in increased expression of SCG2 mRNA] CTD PMID:15033416 PMID:15592348 NCBI chr 9:80,803,074...80,808,646
Ensembl chr 9:80,803,075...80,821,097
JBrowse link
G Tac1 tachykinin, precursor 1 multiple interactions EXP Baclofen inhibits the reaction [Amphetamine results in increased expression of TAC1 mRNA] CTD PMID:15033416 NCBI chr 4:35,679,183...35,687,180
Ensembl chr 4:35,679,704...35,687,178
JBrowse link
G Tnf tumor necrosis factor decreases secretion ISO Baclofen results in decreased secretion of TNF protein CTD PMID:20201957 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
butylscopolamine bromide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Butylscopolammonium Bromide inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268
JBrowse link
carisoprodol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 multiple interactions ISO [CYP2C19 gene polymorphism affects the metabolism of Carisoprodol] which affects the chemical synthesis of Meprobamate; [CYP2C19 protein results in increased metabolism of Carisoprodol] which results in increased chemical synthesis of Meprobamate CTD PMID:12835613 PMID:22527345 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
JBrowse link
G Gabra1 gamma-aminobutyric acid type A receptor subunit alpha 1 multiple interactions ISO Bemegride inhibits the reaction [Carisoprodol results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Carisoprodol binds to and affects the activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein] CTD PMID:19244096 NCBI chr10:26,595,151...26,650,611
Ensembl chr10:26,595,160...26,650,864
JBrowse link
G Gabrb2 gamma-aminobutyric acid type A receptor subunit beta 2 multiple interactions ISO Bemegride inhibits the reaction [Carisoprodol results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Carisoprodol binds to and affects the activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein] CTD PMID:19244096 NCBI chr10:26,936,592...27,156,141
Ensembl chr10:26,936,551...27,151,251
JBrowse link
G Gabrg2 gamma-aminobutyric acid type A receptor subunit gamma 2 multiple interactions ISO Bemegride inhibits the reaction [Carisoprodol results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Carisoprodol binds to and affects the activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein] CTD PMID:19244096 NCBI chr10:26,376,805...26,463,680
Ensembl chr10:26,374,694...26,464,346
JBrowse link
chlorphenesin carbamate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO chlorphenesin carbamate inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268
JBrowse link
chlorzoxazone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyb5a cytochrome b5 type A multiple interactions ISO CYB5A protein promotes the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone] CTD PMID:15728263 NCBI chr18:78,213,067...78,245,677
Ensembl chr18:78,202,342...78,258,535
Ensembl chr18:78,202,342...78,258,535
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 affects metabolic processing EXP CYP1A1 protein affects the metabolism of Chlorzoxazone CTD PMID:15231049 PMID:15879494 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 affects metabolic processing
increases hydroxylation
ISO
EXP
CYP1A2 protein affects the metabolism of Chlorzoxazone
CYP1A2 protein results in increased hydroxylation of Chlorzoxazone
CTD PMID:11911841 PMID:14586387 PMID:15879494 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 affects metabolic processing EXP CYP2B1 protein affects the metabolism of Chlorzoxazone CTD PMID:15879494 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 affects metabolic processing EXP CYP2C11 protein affects the metabolism of Chlorzoxazone CTD PMID:15879494 NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066
JBrowse link
G Cyp2c13 cytochrome P450, family 2, subfamily c, polypeptide 13 affects metabolic processing EXP CYP2C13 protein affects the metabolism of Chlorzoxazone CTD PMID:15879494 NCBI chr 1:238,786,764...238,867,195
Ensembl chr 1:238,786,765...238,867,191
JBrowse link
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 affects metabolic processing EXP CYP2C6V1 protein affects the metabolism of Chlorzoxazone CTD PMID:15879494 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 affects hydroxylation
increases metabolic processing
increases hydroxylation
multiple interactions
affects metabolic processing
increases oxidation
ISO
EXP
CYP2E1 protein affects the hydroxylation of Chlorzoxazone
CYP2E1 protein results in increased metabolism of Chlorzoxazone
CYP2E1 protein results in increased hydroxylation of Chlorzoxazone
[CYP2E1 protein results in increased metabolism of Chlorzoxazone] which results in increased abundance of 6-hydroxychlorzoxazone; [CYP2E1 protein results in increased metabolism of Chlorzoxazone] which results in increased chemical synthesis of 6-hydroxychlorzoxazone; Resveratrol inhibits the reaction [CYP2E1 protein results in increased metabolism of Chlorzoxazone]
CYP2E1 mRNA results in increased metabolism of Chlorzoxazone; CYP2E1 protein results in increased metabolism of Chlorzoxazone
CYP2E1 protein affects the metabolism of Chlorzoxazone
[CYP2E1 protein results in increased metabolism of Chlorzoxazone] which results in increased chemical synthesis of 6-hydroxychlorzoxazone; Imidazoles inhibits the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone]; Isoquinolines inhibits the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone]; Pyridines inhibits the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone]; Quinolines inhibits the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone]
CYP2E1 protein results in increased oxidation of Chlorzoxazone
[5-bromotryptamine analog results in decreased activity of CYP2E1 protein] which results in decreased metabolism of Chlorzoxazone; [5-chlorotryptamine analog results in decreased activity of CYP2E1 protein] which results in decreased metabolism of Chlorzoxazone; [5-fluoro-alpha-methyltryptamine results in decreased activity of CYP2E1 protein] which results in decreased metabolism of Chlorzoxazone; [5-fluorotryptamine analog results in decreased activity of CYP2E1 protein] which results in decreased metabolism of Chlorzoxazone; [5-methoxy-N,N-diisopropyltryptamine analog results in decreased activity of CYP2E1 protein] which results in decreased metabolism of Chlorzoxazone; [5-methyltryptamine analog results in decreased activity of CYP2E1 protein] which results in decreased metabolism of Chlorzoxazone; [7-methyltryptamine analog results in decreased activity of CYP2E1 protein] which results in decreased metabolism of Chlorzoxazone; [Chlormethiazole results in decreased activity of CYP2E1 protein] which results in decreased metabolism of Chlorzoxazone; [Chlorzoxazone results in decreased activity of CYP2E1 protein] which results in decreased degradation of vanoxerine; [CYP2E1 mRNA results in increased metabolism of Chlorzoxazone] which results in increased chemical synthesis of 6-hydroxychlorzoxazone; [CYP2E1 protein results in increased metabolism of Chlorzoxazone] which results in increased chemical synthesis of 6-hydroxychlorzoxazone; [indopan analog results in decreased activity of CYP2E1 protein] which results in decreased metabolism of Chlorzoxazone; [indopan results in decreased activity of CYP2E1 protein] which results in decreased metabolism of Chlorzoxazone; [Methoxydimethyltryptamines analog results in decreased activity of CYP2E1 protein] which results in decreased metabolism of Chlorzoxazone; [N,N-diallyl-5-methoxytryptamine results in decreased activity of CYP2E1 protein] which results in decreased metabolism of Chlorzoxazone; [N,N-diisopropyltryptamine analog results in decreased activity of CYP2E1 protein] which results in decreased metabolism of Chlorzoxazone; [Tryptamines analog results in decreased activity of CYP2E1 protein] which results in decreased metabolism of Chlorzoxazone; Carbaryl inhibits the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone]; chlorfluazuron inhibits the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone]; Chlorpyrifos inhibits the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone]; CYB5A protein promotes the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone]; cypermethrin inhibits the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone]; Disulfiram inhibits the reaction [[CYP2E1 protein results in increased metabolism of Chlorzoxazone] which results in increased chemical synthesis of 6-hydroxychlorzoxazone]; Disulfiram inhibits the reaction [CYP2E1 protein results in increased metabolism of Chlorzoxazone]; Fenitrothion inhibits the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone]; fenvalerate inhibits the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone]; Fomepizole inhibits the reaction [CYP2E1 protein results in increased metabolism of Chlorzoxazone]; isoproturon inhibits the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone]; Malathion inhibits the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone]; perfluorooctane sulfonic acid inhibits the reaction [CYP2E1 protein results in increased oxidation of Chlorzoxazone]; phenthoate inhibits the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone]; profenofos inhibits the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone]
CTD PMID:7747284 PMID:8558417 PMID:8858968 PMID:9817075 PMID:9825833 More... NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 affects metabolic processing EXP CYP3A2 protein affects the metabolism of Chlorzoxazone CTD PMID:15879494 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 increases hydroxylation
affects metabolic processing
EXP CYP3A23-3A1 protein results in increased hydroxylation of Chlorzoxazone
CYP3A23-3A1 protein affects the metabolism of Chlorzoxazone
CTD PMID:11911841 PMID:15879494 NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 affects metabolic processing EXP CYP3A9 protein affects the metabolism of Chlorzoxazone CTD PMID:15879494 NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422
JBrowse link
G Ins2 insulin 2 multiple interactions ISO INS protein inhibits the reaction [stearic acid results in increased hydroxylation of Chlorzoxazone] CTD PMID:26739624 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
JBrowse link
G Kcnn4 potassium calcium-activated channel subfamily N member 4 increases activity ISO Chlorzoxazone results in increased activity of KCNN4 protein CTD PMID:14985237 NCBI chr 1:79,956,380...79,974,354
Ensembl chr 1:79,959,322...79,974,340
JBrowse link
G Nat2 N-acetyltransferase 2 affects metabolic processing ISO NAT2 protein affects the metabolism of Chlorzoxazone CTD PMID:14586387 NCBI chr16:22,207,362...22,238,513
Ensembl chr16:22,208,194...22,238,520
JBrowse link
G Xdh xanthine dehydrogenase affects metabolic processing ISO XDH protein affects the metabolism of Chlorzoxazone CTD PMID:14586387 NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268
JBrowse link
cisatracurium term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdh1 cadherin 1 multiple interactions
increases expression
ISO CXCR4 protein inhibits the reaction [cisatracurium results in increased expression of CDH1 protein]; TGFB1 protein inhibits the reaction [cisatracurium results in increased expression of CDH1 protein] CTD PMID:33617803 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
JBrowse link
G Cdh2 cadherin 2 decreases expression
multiple interactions
ISO cisatracurium results in decreased expression of CDH2 protein
CXCR4 protein inhibits the reaction [cisatracurium results in decreased expression of CDH2 protein]; TGFB1 protein inhibits the reaction [cisatracurium results in decreased expression of CDH2 protein]
CTD PMID:33617803 NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167
JBrowse link
G Chrna3 cholinergic receptor nicotinic alpha 3 subunit multiple interactions ISO cisatracurium inhibits the reaction [Acetylcholine results in increased activity of [CHRNA3 protein binds to CHRNB2 protein]]; cisatracurium inhibits the reaction [Acetylcholine results in increased activity of [CHRNA3 protein binds to CHRNB4 protein]] CTD PMID:16931985 NCBI chr 8:55,401,981...55,415,012
Ensembl chr 8:55,401,702...55,415,165
JBrowse link
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit multiple interactions ISO cisatracurium inhibits the reaction [Acetylcholine results in increased activity of [CHRNA4 protein binds to CHRNB2 protein]] CTD PMID:16931985 NCBI chr 3:168,136,246...168,157,839
Ensembl chr 3:168,136,266...168,156,957
JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit multiple interactions ISO cisatracurium inhibits the reaction [Acetylcholine results in increased activity of CHRNA7 protein] CTD PMID:16931985 NCBI chr 1:116,715,286...116,837,223
Ensembl chr 1:116,714,711...116,837,240
JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit multiple interactions ISO cisatracurium inhibits the reaction [Acetylcholine results in increased activity of [CHRNA3 protein binds to CHRNB2 protein]]; cisatracurium inhibits the reaction [Acetylcholine results in increased activity of [CHRNA4 protein binds to CHRNB2 protein]] CTD PMID:16931985 NCBI chr 2:175,181,402...175,189,619
Ensembl chr 2:175,181,402...175,189,619
JBrowse link
G Chrnb4 cholinergic receptor nicotinic beta 4 subunit multiple interactions ISO cisatracurium inhibits the reaction [Acetylcholine results in increased activity of [CHRNA3 protein binds to CHRNB4 protein]] CTD PMID:16931985 NCBI chr 8:55,418,379...55,436,967
Ensembl chr 8:55,418,313...55,437,027
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 decreases expression
multiple interactions
ISO cisatracurium results in decreased expression of CXCR4 mRNA; cisatracurium results in decreased expression of CXCR4 protein
CXCR4 protein inhibits the reaction [cisatracurium results in decreased expression of CDH2 protein]; CXCR4 protein inhibits the reaction [cisatracurium results in decreased expression of VIM protein]; CXCR4 protein inhibits the reaction [cisatracurium results in increased expression of CDH1 protein]; TGFB1 protein inhibits the reaction [cisatracurium results in decreased expression of CXCR4 protein]
CTD PMID:33617803 NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions
decreases expression
ISO TGFB1 protein inhibits the reaction [cisatracurium results in decreased expression of CDH2 protein]; TGFB1 protein inhibits the reaction [cisatracurium results in decreased expression of CXCR4 protein]; TGFB1 protein inhibits the reaction [cisatracurium results in decreased expression of TGFBR1 protein]; TGFB1 protein inhibits the reaction [cisatracurium results in decreased expression of VIM protein]; TGFB1 protein inhibits the reaction [cisatracurium results in increased expression of CDH1 protein]
cisatracurium results in decreased expression of TGFB1 protein
CTD PMID:33617803 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 decreases expression
multiple interactions
ISO cisatracurium results in decreased expression of TGFBR1 protein
TGFB1 protein inhibits the reaction [cisatracurium results in decreased expression of TGFBR1 protein]
CTD PMID:33617803 NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777
JBrowse link
G Vim vimentin decreases expression
multiple interactions
ISO cisatracurium results in decreased expression of VIM protein
CXCR4 protein inhibits the reaction [cisatracurium results in decreased expression of VIM protein]; TGFB1 protein inhibits the reaction [cisatracurium results in decreased expression of VIM protein]
CTD PMID:33617803 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
JBrowse link
clidinium term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO clidinium inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268
JBrowse link
cyclobenzaprine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO cyclobenzaprine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268
JBrowse link
dantrolene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg2 ATP binding cassette subfamily G member 2 affects transport ISO ABCG2 protein affects the transport of Dantrolene CTD PMID:18322075 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409
JBrowse link
G Ace2 angiotensin I converting enzyme 2 increases expression ISO Dantrolene results in increased expression of ACE2 mRNA CTD PMID:32808185 NCBI chr  X:30,293,597...30,340,961
Ensembl chr  X:30,293,589...30,340,977
JBrowse link
G Atf4 activating transcription factor 4 decreases expression
multiple interactions
EXP
ISO
Dantrolene results in decreased expression of ATF4 protein
Dantrolene affects the reaction [perfluorooctanoic acid results in increased expression of ATF4 protein]; Dantrolene inhibits the reaction [Thapsigargin results in increased expression of ATF4 protein]; Dantrolene promotes the reaction [Thapsigargin results in increased expression of ATF4 mRNA]
CTD PMID:15921666 PMID:32578922 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO Dantrolene inhibits the reaction [Halothane results in increased expression of BAX mRNA] CTD PMID:32795494 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression EXP Dantrolene results in increased expression of BCL2 protein CTD PMID:10854250 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bcl2l11 BCL2 like 11 multiple interactions ISO Dantrolene inhibits the reaction [Halothane results in increased expression of BCL2L11 mRNA] CTD PMID:32795494 NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068
JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions ISO Dantrolene inhibits the reaction [Oxygen deficiency results in increased secretion of BDNF protein] CTD PMID:16553631 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G Capn1 calpain 1 decreases expression EXP Dantrolene results in decreased expression of CAPN1 mRNA; Dantrolene results in decreased expression of CAPN1 protein CTD PMID:11236903 NCBI chr 1:203,275,912...203,300,848
Ensembl chr 1:203,277,344...203,300,177
JBrowse link
G Capn2 calpain 2 decreases expression EXP Dantrolene results in decreased expression of CAPN2 mRNA; Dantrolene results in decreased expression of CAPN2 protein CTD PMID:11236903 NCBI chr13:94,150,244...94,200,969
Ensembl chr13:94,150,240...94,200,969
JBrowse link
G Capn3 calpain 3 decreases expression EXP Dantrolene results in decreased expression of CAPN3 mRNA; Dantrolene results in decreased expression of CAPN3 protein CTD PMID:11236903 NCBI chr 3:107,407,518...107,457,858
Ensembl chr 3:107,407,850...107,457,858
JBrowse link
G Casp3 caspase 3 multiple interactions EXP
ISO
Dantrolene inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]
Dantrolene inhibits the reaction [Indomethacin results in increased activity of CASP3 protein]
CTD PMID:17079870 PMID:23022152 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp9 caspase 9 multiple interactions ISO Dantrolene inhibits the reaction [Indomethacin results in increased activity of CASP9 protein] CTD PMID:23022152 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases expression EXP Dantrolene results in decreased expression of CCL2 mRNA CTD PMID:25051504 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 affects expression EXP Dantrolene affects the expression of CCL5 protein CTD PMID:25051504 NCBI chr10:68,322,826...68,327,365
Ensembl chr10:68,322,829...68,327,377
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions ISO Dantrolene inhibits the reaction [Halothane results in increased expression of CXCL2 mRNA] CTD PMID:32795494 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO
EXP
Dantrolene inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein] CTD PMID:18493746 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions ISO Dantrolene inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein] CTD PMID:18493746 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 decreases phosphorylation
multiple interactions
EXP
ISO
Dantrolene results in decreased phosphorylation of DDIT3 protein
Dantrolene inhibits the reaction [Halothane results in increased expression of DDIT3 mRNA]; Dantrolene promotes the reaction [perfluorooctanoic acid results in increased expression of DDIT3 mRNA]; Dantrolene promotes the reaction [perfluorooctanoic acid results in increased expression of DDIT3 protein]
CTD PMID:15921666 PMID:32578922 PMID:32795494 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Edn1 endothelin 1 decreases activity EXP Dantrolene results in decreased activity of EDN1 protein CTD PMID:12628492 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 decreases phosphorylation EXP Dantrolene results in decreased phosphorylation of EIF2AK3 protein CTD PMID:15921666 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha decreases phosphorylation
multiple interactions
EXP
ISO
Dantrolene results in decreased phosphorylation of EIF2S1 protein
Dantrolene inhibits the reaction [tributyltin results in increased phosphorylation of EIF2S1 protein]
CTD PMID:15921666 PMID:23743301 NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225
JBrowse link
G Fkbp1a FKBP prolyl isomerase 1A multiple interactions ISO Dantrolene inhibits the reaction [Halothane results in increased expression of FKBP1A mRNA] CTD PMID:32795494 NCBI chr 3:140,040,359...140,060,107
Ensembl chr 3:140,040,278...140,060,743
JBrowse link
G Fkbp1b FKBP prolyl isomerase 1B multiple interactions ISO Dantrolene inhibits the reaction [Halothane results in increased expression of FKBP1B mRNA] CTD PMID:32795494 NCBI chr 6:27,832,128...27,850,600
Ensembl chr 6:27,838,802...27,848,653
JBrowse link
G Gfap glial fibrillary acidic protein multiple interactions EXP Dantrolene inhibits the reaction [diphenylditelluride results in decreased phosphorylation of GFAP protein]; Dantrolene inhibits the reaction [diphenylditelluride results in increased phosphorylation of GFAP protein] CTD PMID:21863293 PMID:21879721 NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions ISO Dantrolene inhibits the reaction [Halothane results in increased expression of GPT protein] CTD PMID:32795494 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO Dantrolene inhibits the reaction [Halothane results in increased expression of HMOX1 mRNA] CTD PMID:32795494 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Homer1 homer scaffold protein 1 multiple interactions ISO Dantrolene inhibits the reaction [Halothane results in increased expression of HOMER1 mRNA] CTD PMID:32795494 NCBI chr 2:24,542,777...24,645,715
Ensembl chr 2:24,543,093...24,644,785
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions ISO Dantrolene inhibits the reaction [tributyltin results in increased expression of HSPA5 protein] CTD PMID:23743301 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
JBrowse link
G Ifng interferon gamma multiple interactions ISO Dantrolene inhibits the reaction [taurolithocholic acid 3-sulfate results in increased expression of IFNG mRNA] CTD PMID:22517774 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Igf1 insulin-like growth factor 1 decreases response to substance ISO Dantrolene results in decreased susceptibility to IGF1 protein CTD PMID:16485066 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Igf2 insulin-like growth factor 2 decreases response to substance ISO Dantrolene results in decreased susceptibility to IGF2 protein CTD PMID:16485066 NCBI chr 1:197,814,409...197,831,802
Ensembl chr 1:197,814,410...197,823,018
JBrowse link
G Il10 interleukin 10 multiple interactions
affects expression
ISO
EXP
Dantrolene inhibits the reaction [[chlorocresol results in increased activity of RYR1 protein] inhibits the reaction [Lipopolysaccharides results in increased expression of IL10 protein]]
Dantrolene affects the expression of IL10 protein
CTD PMID:17707769 PMID:25051504 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il1b interleukin 1 beta affects expression
multiple interactions
EXP
ISO
Dantrolene affects the expression of IL1B mRNA
Dantrolene inhibits the reaction [Halothane results in increased expression of IL1B mRNA]
CTD PMID:25051504 PMID:32795494 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 multiple interactions ISO Dantrolene inhibits the reaction [taurolithocholic acid 3-sulfate results in increased expression of IL6 mRNA] CTD PMID:22517774 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO Dantrolene results in decreased activity of KCNH2 protein CTD PMID:24052561 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008
JBrowse link
G Kcnj11 potassium inwardly-rectifying channel, subfamily J, member 11 multiple interactions ISO Dantrolene inhibits the reaction [KCNJ11 protein mutant form results in increased abundance of Calcium] CTD PMID:17189350 NCBI chr 1:96,591,048...96,594,574
Ensembl chr 1:96,591,049...96,594,082
JBrowse link
G Lep leptin decreases expression EXP Dantrolene results in decreased expression of LEP protein CTD PMID:25051504 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link
G Mef2a myocyte enhancer factor 2a multiple interactions EXP Dantrolene inhibits the reaction [Caffeine results in increased expression of MEF2A mRNA]; Dantrolene inhibits the reaction [Caffeine results in increased expression of MEF2A protein] CTD PMID:25093688 NCBI chr 1:120,847,874...120,982,488
Ensembl chr 1:120,850,080...120,981,948
JBrowse link
G Mef2c myocyte enhancer factor 2C multiple interactions EXP Dantrolene inhibits the reaction [Caffeine results in increased expression of MEF2C mRNA]; Dantrolene inhibits the reaction [Caffeine results in increased expression of MEF2C protein] CTD PMID:25093688 NCBI chr 2:13,973,299...14,136,065
Ensembl chr 2:13,993,438...14,132,880
JBrowse link
G Myh7 myosin heavy chain 7 multiple interactions EXP Dantrolene inhibits the reaction [Caffeine results in increased expression of MYH7 mRNA] CTD PMID:25093688 NCBI chr15:28,446,550...28,469,888
Ensembl chr15:28,446,550...28,468,217
JBrowse link
G Nefl neurofilament light chain multiple interactions EXP Dantrolene inhibits the reaction [diphenylditelluride results in decreased phosphorylation of NEFL protein]; Dantrolene inhibits the reaction [diphenylditelluride results in increased phosphorylation of NEFL protein] CTD PMID:21863293 PMID:21879721 NCBI chr15:42,301,920...42,305,793
Ensembl chr15:42,301,916...42,305,793
JBrowse link
G Nefm neurofilament medium chain multiple interactions EXP Dantrolene inhibits the reaction [diphenylditelluride results in decreased phosphorylation of NEFM protein]; Dantrolene inhibits the reaction [diphenylditelluride results in increased phosphorylation of NEFM protein] CTD PMID:21863293 PMID:21879721 NCBI chr15:42,360,449...42,365,753
Ensembl chr15:42,360,454...42,365,755
JBrowse link
G Nppa natriuretic peptide A multiple interactions EXP Dantrolene inhibits the reaction [Caffeine results in increased expression of NPPA mRNA] CTD PMID:25093688 NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351
JBrowse link
G Nppb natriuretic peptide B multiple interactions EXP Dantrolene inhibits the reaction [Caffeine results in increased expression of NPPB mRNA] CTD PMID:25093688 NCBI chr 5:158,416,813...158,418,175
Ensembl chr 5:158,416,866...158,418,168
JBrowse link
G Ryr1 ryanodine receptor 1 multiple interactions ISO Dantrolene inhibits the reaction [[chlorocresol results in increased activity of RYR1 protein] inhibits the reaction [Lipopolysaccharides results in increased expression of IL10 protein]]; Dantrolene inhibits the reaction [[chlorocresol results in increased activity of RYR1 protein] which results in increased transport of Calcium] CTD PMID:17707769 NCBI chr 1:84,292,578...84,423,799
Ensembl chr 1:84,292,578...84,423,812
JBrowse link
G Ryr2 ryanodine receptor 2 multiple interactions EXP Dantrolene inhibits the reaction [Caffeine promotes the reaction [RYR2 protein results in increased secretion of Calcium]] CTD PMID:12887973 NCBI chr17:58,389,925...58,975,641
Ensembl chr17:58,389,925...58,975,142
JBrowse link
G S100a8 S100 calcium binding protein A8 multiple interactions ISO Dantrolene inhibits the reaction [Halothane results in increased expression of S100A8 mRNA] CTD PMID:32795494 NCBI chr 2:176,166,517...176,167,645
Ensembl chr 2:176,167,124...176,167,643
JBrowse link
G S100a9 S100 calcium binding protein A9 multiple interactions ISO Dantrolene inhibits the reaction [Halothane results in increased expression of S100A9 mRNA] CTD PMID:32795494 NCBI chr 2:176,190,361...176,193,182
Ensembl chr 2:176,190,361...176,193,230
JBrowse link
G Star steroidogenic acute regulatory protein multiple interactions ISO Dantrolene inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of STAR mRNA] CTD PMID:23183170 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672
JBrowse link
G Tnf tumor necrosis factor decreases expression
multiple interactions
EXP
ISO
Dantrolene results in decreased expression of TNF protein
Dantrolene inhibits the reaction [Halothane results in increased expression of TNF mRNA]
CTD PMID:11236903 PMID:32795494 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions ISO Dantrolene inhibits the reaction [Halothane results in increased expression of VCAM1 mRNA] CTD PMID:32795494 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
JBrowse link
G Vim vimentin multiple interactions EXP Dantrolene inhibits the reaction [diphenylditelluride results in decreased phosphorylation of VIM protein]; Dantrolene inhibits the reaction [diphenylditelluride results in increased phosphorylation of VIM protein] CTD PMID:21863293 PMID:21879721 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
JBrowse link
G Xbp1 X-box binding protein 1 multiple interactions ISO Dantrolene inhibits the reaction [perfluorooctanoic acid results in increased expression of XBP1 mRNA alternative form]; Dantrolene inhibits the reaction [Thapsigargin results in increased expression of XBP1 mRNA alternative form] CTD PMID:32578922 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693
JBrowse link
darifenacin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrm2 cholinergic receptor, muscarinic 2 multiple interactions ISO darifenacin binds to and results in decreased activity of CHRM2 protein CTD PMID:15140916 NCBI chr 4:65,015,408...65,149,104
Ensembl chr 4:65,014,144...65,149,103
JBrowse link
G Chrm3 cholinergic receptor, muscarinic 3 multiple interactions ISO darifenacin binds to and results in decreased activity of CHRM3 protein CTD PMID:11488427 PMID:15140916 NCBI chr17:60,005,137...60,467,250
Ensembl chr17:60,005,202...60,467,278
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO darifenacin results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008
JBrowse link
decamethonium term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bche butyrylcholinesterase decreases activity ISO decamethonium results in decreased activity of BCHE protein CTD PMID:31173753 NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148
JBrowse link
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit multiple interactions ISO Carbachol inhibits the reaction [decamethonium binds to and results in decreased activity of [CHRNA4 protein binds to CHRNB2 protein]]; decamethonium binds to and results in decreased activity of [CHRNA4 protein binds to CHRNB2 protein]; decamethonium inhibits the reaction [epibatidine binds to [CHRNA4 protein binds to CHRNB2 protein]]; decamethonium results in decreased activity of [CHRNA4 protein binds to CHRNB2 protein] CTD PMID:14645658 NCBI chr 3:168,136,246...168,157,839
Ensembl chr 3:168,136,266...168,156,957
JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit multiple interactions ISO Carbachol inhibits the reaction [decamethonium binds to and results in decreased activity of [CHRNA4 protein binds to CHRNB2 protein]]; decamethonium binds to and results in decreased activity of [CHRNA4 protein binds to CHRNB2 protein]; decamethonium inhibits the reaction [epibatidine binds to [CHRNA4 protein binds to CHRNB2 protein]]; decamethonium results in decreased activity of [CHRNA4 protein binds to CHRNB2 protein] CTD PMID:14645658 NCBI chr 2:175,181,402...175,189,619
Ensembl chr 2:175,181,402...175,189,619
JBrowse link
dicyclomine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Dicyclomine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268
JBrowse link
dihydro-beta-erythroidine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO Dihydro-beta-Erythroidine inhibits the reaction [Nicotine results in increased phosphorylation of and results in increased activity of AKT1 protein] CTD PMID:12511591 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Atoh1 atonal bHLH transcription factor 1 multiple interactions ISO Dihydro-beta-Erythroidine inhibits the reaction [Nicotine results in increased expression of ATOH1 mRNA] CTD PMID:23056257 NCBI chr 4:93,912,068...93,914,163
Ensembl chr 4:93,912,068...93,914,154
JBrowse link
G Ccnd1 cyclin D1 multiple interactions ISO Dihydro-beta-Erythroidine inhibits the reaction [Nicotine results in decreased expression of CCND1 mRNA] CTD PMID:23056257 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Cdk4 cyclin-dependent kinase 4 multiple interactions ISO Dihydro-beta-Erythroidine inhibits the reaction [Nicotine results in decreased expression of CDK4 protein] CTD PMID:15231866 NCBI chr 7:62,885,647...62,889,562
Ensembl chr 7:62,883,105...62,942,403
JBrowse link
G Chrna2 cholinergic receptor nicotinic alpha 2 subunit multiple interactions EXP dihydro-beta-erythroidine affects binding to Chrna2 protein; dihydro-beta-erythroidine inhibits the reaction [epibatidine affects binding to Chrna2 protein] in rat retina RGD PMID:16129735 RGD:2303195 NCBI chr15:40,342,317...40,358,601
Ensembl chr15:40,342,317...40,358,601
JBrowse link
G Chrna3 cholinergic receptor nicotinic alpha 3 subunit multiple interactions EXP Dihydro-beta-Erythroidine results in decreased activity of [CHRNA3 protein binds to CHRNB4 protein]
dihydro-beta-erythroidine affects binding [Epibatidine binds to Chrna3 protein]
CTD PMID:9687574 PMID:16129735 PMID:15016836 RGD:2303195, RGD:2303194 NCBI chr 8:55,401,981...55,415,012
Ensembl chr 8:55,401,702...55,415,165
JBrowse link
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit multiple interactions
affects binding
ISO
EXP
Carbachol inhibits the reaction [Dihydro-beta-Erythroidine binds to and results in decreased activity of [CHRNA4 protein binds to CHRNB2 protein]]; Dihydro-beta-Erythroidine binds to and results in decreased activity of [CHRNA4 protein binds to CHRNB2 protein]; Dihydro-beta-Erythroidine inhibits the reaction [1-Butanol binds to and results in increased activity of [CHRNA4 protein binds to CHRNB2 protein]]; Dihydro-beta-Erythroidine inhibits the reaction [epibatidine binds to [CHRNA4 protein binds to CHRNB2 protein]]; Dihydro-beta-Erythroidine results in decreased activity of [CHRNA4 protein binds to CHRNB2 protein]
dihydro-beta-erythroidine affects binding to Chrna4 protein; dihydro-beta-erythroidine inhibits the reaction [epibatidine affects binding to Chrna4 protein] in rat retina
dihydro-beta-erythroidine affects binding to Chrna4 protein; dihydro-beta-erythroidine competes with [Epibatidine binds to Chrna4 protein]
[Dihydro-beta-Erythroidine binds to and results in decreased activity of [CHRNA4 protein binds to CHRNB2 protein]] which results in decreased susceptibility to Nicotine; Dihydro-beta-Erythroidine affects the activity of [CHRNA4 protein binds to CHRNB2 protein]; Dihydro-beta-Erythroidine analog inhibits the reaction [Nicotine results in increased expression of CHRNA4 mRNA]; Dihydro-beta-Erythroidine inhibits the reaction [[pozanicline binds to and results in increased activity of [CHRNA4 protein binds to CHRNB2 protein]] which results in increased secretion of Acetylcholine]; Dihydro-beta-Erythroidine results in decreased activity of [CHRNA4 protein binds to CHRNB2 protein]
Dihydro-beta-Erythroidine binds to and results in decreased activity of [CHRNA4 protein binds to CHRNB2 protein]; Dihydro-beta-Erythroidine inhibits the reaction [3-(2-(pyrrolidinyl)methoxy)pyridine analog results in increased activity of [CHRNA4 protein binds to CHRNB2 protein]]
[CHRNA4 protein binds to CHRNB4 protein] which binds to Dihydro-beta-Erythroidine
CTD PMID:9687574 PMID:10945867 PMID:11600638 PMID:12604691 PMID:14645658 More... RGD:2303195, RGD:2303194 NCBI chr 3:168,136,246...168,157,839
Ensembl chr 3:168,136,266...168,156,957
JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit increases activity
multiple interactions
affects response to substance
ISO
EXP
Dihydro-beta-Erythroidine results in increased activity of CHRNA7 protein mutant form
Dihydro-beta-Erythroidine affects the reaction [iodo-alpha-bungarotoxin binds to CHRNA7 protein]
CHRNA7 protein mutant form affects the susceptibility to Dihydro-beta-Erythroidine
Dihydro-beta-Erythroidine binds to and results in decreased activity of CHRNA7 protein
CTD PMID:10082212 PMID:19448648 NCBI chr 1:116,715,286...116,837,223
Ensembl chr 1:116,714,711...116,837,240
JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit multiple interactions ISO
EXP
Carbachol inhibits the reaction [Dihydro-beta-Erythroidine binds to and results in decreased activity of [CHRNA4 protein binds to CHRNB2 protein]]; Dihydro-beta-Erythroidine binds to and results in decreased activity of [CHRNA4 protein binds to CHRNB2 protein]; Dihydro-beta-Erythroidine inhibits the reaction [1-Butanol binds to and results in increased activity of [CHRNA4 protein binds to CHRNB2 protein]]; Dihydro-beta-Erythroidine inhibits the reaction [[5-iodo-3-(2-azetidinylmethoxy)pyridine binds to and results in increased activity of CHRNB2 protein] which results in decreased uptake of Calcium]; Dihydro-beta-Erythroidine inhibits the reaction [epibatidine binds to [CHRNA4 protein binds to CHRNB2 protein]]; Dihydro-beta-Erythroidine results in decreased activity of [CHRNA4 protein binds to CHRNB2 protein]
dihydro-beta-erythroidine affects binding to Chrnb2 protein; dihydro-beta-erythroidine inhibits the reaction [epibatidine affects binding to Chrnb2 protein] in rat retina
dihydro-beta-erythroidine affects binding to Chrnb2 protein; dihydro-beta-erythroidine competes with [Epibatidine binds to Chrnb2 protein]
Dihydro-beta-Erythroidine binds to and results in decreased activity of [CHRNA4 protein binds to CHRNB2 protein]; Dihydro-beta-Erythroidine inhibits the reaction [3-(2-(pyrrolidinyl)methoxy)pyridine analog results in increased activity of [CHRNA4 protein binds to CHRNB2 protein]]
[Dihydro-beta-Erythroidine binds to and results in decreased activity of [CHRNA4 protein binds to CHRNB2 protein]] which results in decreased susceptibility to Nicotine; Dihydro-beta-Erythroidine affects the activity of [CHRNA4 protein binds to CHRNB2 protein]; Dihydro-beta-Erythroidine inhibits the reaction [[pozanicline binds to and results in increased activity of [CHRNA4 protein binds to CHRNB2 protein]] which results in increased secretion of Acetylcholine]; Dihydro-beta-Erythroidine results in decreased activity of [CHRNA4 protein binds to CHRNB2 protein]
CTD PMID:10945867 PMID:11600638 PMID:12604691 PMID:14645658 PMID:16569710 More... RGD:2303195, RGD:2303194 NCBI chr 2:175,181,402...175,189,619
Ensembl chr 2:175,181,402...175,189,619
JBrowse link
G Chrnb3 cholinergic receptor nicotinic beta 3 subunit multiple interactions EXP dihydro-beta-erythroidine affects binding to Chrnb3 protein; dihydro-beta-erythroidine inhibits the reaction [epibatidine affects binding to Chrnb3 protein] in rat retina RGD PMID:16129735 RGD:2303195 NCBI chr16:64,713,438...64,751,360
Ensembl chr16:64,714,169...64,751,360
JBrowse link
G Chrnb4 cholinergic receptor nicotinic beta 4 subunit affects binding
multiple interactions
EXP [CHRNA4 protein binds to CHRNB4 protein] which binds to Dihydro-beta-Erythroidine
Dihydro-beta-Erythroidine results in decreased activity of [CHRNA3 protein binds to CHRNB4 protein]
CTD PMID:9687574 NCBI chr 8:55,418,379...55,436,967
Ensembl chr 8:55,418,313...55,437,027
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 multiple interactions ISO [Mecamylamine co-treated with Dihydro-beta-Erythroidine co-treated with Bungarotoxins] inhibits the reaction [Nicotine results in increased expression of CXCR4 protein] CTD PMID:20457658 NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
JBrowse link
G Dnmt1 DNA methyltransferase 1 multiple interactions EXP Dihydro-beta-Erythroidine analog inhibits the reaction [Nicotine results in decreased expression of DNMT1 mRNA] CTD PMID:28555334 NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659
JBrowse link
G Gad1 glutamate decarboxylase 1 multiple interactions EXP Dihydro-beta-Erythroidine analog inhibits the reaction [Nicotine results in increased expression of GAD1 mRNA] CTD PMID:28555334 NCBI chr 3:55,369,704...55,410,335
Ensembl chr 3:55,369,704...55,410,333
JBrowse link
G Slc6a3 solute carrier family 6 member 3 multiple interactions EXP Dihydro-beta-Erythroidine affects the reaction [Nicotine results in decreased activity of SLC6A3 protein] CTD PMID:23999947 NCBI chr 1:29,709,443...29,750,413
Ensembl chr 1:29,709,443...29,750,413
JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11B multiple interactions EXP Dihydro-beta-Erythroidine inhibits the reaction [Nicotine results in increased expression of TNFRSF11B mRNA] CTD PMID:29981921 NCBI chr 7:85,566,520...85,594,526
Ensembl chr 7:85,566,520...85,594,538
JBrowse link
G Tnfsf11 TNF superfamily member 11 multiple interactions EXP Dihydro-beta-Erythroidine inhibits the reaction [Nicotine results in decreased expression of TNFSF11 mRNA] CTD PMID:29981921 NCBI chr15:53,674,990...53,705,171
Ensembl chr15:53,673,877...53,705,445
JBrowse link
glycycoumarin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pparg peroxisome proliferator-activated receptor gamma affects binding ISO glycycoumarin binds to PPARG protein CTD PMID:14608046 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
midazolam term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 decreases activity
multiple interactions
ISO Midazolam results in decreased activity of ABCB11 protein
Midazolam inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]
CTD PMID:20829430 PMID:24014644 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A increases expression ISO Midazolam results in increased expression of ABCB1 protein CTD PMID:8632764 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcb6 ATP binding cassette subfamily B member 6 multiple interactions
decreases metabolic processing
ISO [ABCB6 gene mutant form results in decreased expression of CYP3A11 mRNA] inhibits the reaction [CYP3A11 protein results in increased metabolism of Midazolam]; [ABCB6 gene mutant form results in decreased expression of CYP3A11 protein] inhibits the reaction [CYP3A11 protein results in increased metabolism of Midazolam]
ABCB6 gene mutant form results in decreased metabolism of Midazolam
CTD PMID:25623066 NCBI chr 9:76,668,554...76,677,263
Ensembl chr 9:76,668,554...76,676,924
JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression EXP Midazolam results in increased expression of BCL2 CTD PMID:17715682 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases activity ISO Midazolam results in decreased activity of CYP1A1 protein CTD PMID:18420780 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases activity ISO Midazolam results in decreased activity of CYP1B1 protein CTD PMID:18420780 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 decreases activity ISO Midazolam results in decreased activity of CYP2B10 protein CTD PMID:18420780 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 decreases activity ISO Midazolam results in decreased activity of CYP2C29 protein CTD PMID:18420780
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 decreases activity ISO Midazolam results in decreased activity of CYP2D6 protein CTD PMID:18420780 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases metabolic processing ISO CYP2E1 protein results in increased metabolism of Midazolam CTD PMID:17590308 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases hydroxylation
increases glucuronidation
affects metabolic processing
decreases abundance
increases metabolic processing
increases expression
increases oxidation
multiple interactions
EXP
ISO
CYP3A2 protein results in increased hydroxylation of Midazolam
CYP3A4 protein results in increased glucuronidation of Midazolam
CYP3A4 gene polymorphism affects the metabolism of Midazolam; CYP3A4 protein affects the metabolism of Midazolam
CYP3A4 protein results in decreased abundance of Midazolam
CYP3A4 protein results in increased metabolism of Midazolam
CYP3A4 protein results in increased hydroxylation of Midazolam
Midazolam results in increased expression of CYP3A4 mRNA
CYP3A4 protein results in increased oxidation of Midazolam
[3-hydroxyflavone results in increased activity of CYP3A4 protein] which results in increased metabolism of Midazolam; [5-hydroxyflavone results in increased activity of CYP3A4 protein] which results in increased metabolism of Midazolam; [6-hydroxyflavone results in increased activity of CYP3A4 protein] which results in increased metabolism of Midazolam; [6-methylflavone results in increased activity of CYP3A4 protein] which results in increased metabolism of Midazolam; [7-hydroxyflavone results in increased activity of CYP3A4 protein] which results in increased metabolism of Midazolam; [[3-hydroxyflavone results in increased activity of CYP3A4 protein] which results in increased metabolism of Midazolam] which results in increased chemical synthesis of 1-hydroxymethylmidazolam; [[5-hydroxyflavone results in increased activity of CYP3A4 protein] which results in increased metabolism of Midazolam] which results in increased chemical synthesis of 1-hydroxymethylmidazolam; [[6-hydroxyflavone results in increased activity of CYP3A4 protein] which results in increased metabolism of Midazolam] which results in increased chemical synthesis of 1-hydroxymethylmidazolam; [[6-methylflavone results in increased activity of CYP3A4 protein] which results in increased metabolism of Midazolam] which results in increased chemical synthesis of 1-hydroxymethylmidazolam; [[7-hydroxyflavone results in increased activity of CYP3A4 protein] which results in increased metabolism of Midazolam] which results in increased chemical synthesis of 1-hydroxymethylmidazolam; [[alpha-naphthoflavone results in increased activity of CYP3A4 protein] which results in increased metabolism of Midazolam] which results in increased chemical synthesis of 1-hydroxymethylmidazolam; [[artemetin results in increased activity of CYP3A4 protein] which results in increased metabolism of Midazolam] which results in increased chemical synthesis of 1-hydroxymethylmidazolam; [[beta-Naphthoflavone results in increased activity of CYP3A4 protein] which results in increased metabolism of Midazolam] which results in increased chemical synthesis of 1-hydroxymethylmidazolam; [[chrysin results in increased activity of CYP3A4 protein] which results in increased metabolism of Midazolam] which results in increased chemical synthesis of 1-hydroxymethylmidazolam; [[eupatilin results in increased activity of CYP3A4 protein] which results in increased metabolism of Midazolam] which results in increased chemical synthesis of 1-hydroxymethylmidazolam; [[flavone results in increased activity of CYP3A4 protein] which results in increased metabolism of Midazolam] which results in increased chemical synthesis of 1-hydroxymethylmidazolam; [[galangin results in increased activity of CYP3A4 protein] which results in increased metabolism of Midazolam] which results in increased chemical synthesis of 1-hydroxymethylmidazolam; [[nobiletin results in increased activity of CYP3A4 protein] which results in increased metabolism of Midazolam] which results in increased chemical synthesis of 1-hydroxymethylmidazolam; [[sinensetin analog results in increased activity of CYP3A4 protein] which results in increased metabolism of Midazolam] which results in increased chemical synthesis of 1-hydroxymethylmidazolam; [[sinensetin results in increased activity of CYP3A4 protein] which results in increased metabolism of Midazolam] which results in increased chemical synthesis of 1-hydroxymethylmidazolam; [[tangeretin results in increased activity of CYP3A4 protein] which results in increased metabolism of Midazolam] which results in increased chemical synthesis of 1-hydroxymethylmidazolam; [alpha-naphthoflavone results in increased activity of CYP3A4 protein] which results in increased metabolism of Midazolam; [artemetin results in increased activity of CYP3A4 protein] which results in increased metabolism of Midazolam; [beta-Naphthoflavone results in increased activity of CYP3A4 protein] which results in increased metabolism of Midazolam; [Carbamazepine results in increased expression of CYP3A4 protein] which results in decreased abundance of Midazolam; [chrysin results in increased activity of CYP3A4 protein] which results in increased metabolism of Midazolam; [CYP3A4 protein results in increased hydroxylation of Midazolam] which results in increased abundance of 1-hydroxymethylmidazolam; [CYP3A4 protein results in increased hydroxylation of Midazolam] which results in increased abundance of 4-hydroxymidazolam; [CYP3A4 protein results in increased hydroxylation of Midazolam] which results in increased chemical synthesis of 1-hydroxymethylmidazolam; [CYP3A4 protein results in increased oxidation of Midazolam] which results in increased chemical synthesis of 1-hydroxymethylmidazolam; [CYP3A4 protein results in increased oxidation of Midazolam] which results in increased chemical synthesis of 4-hydroxymidazolam; [Dexamethasone results in increased expression of CYP3A4 protein] which results in decreased abundance of Midazolam; [eupatilin results in increased activity of CYP3A4 protein] which results in increased metabolism of Midazolam; [flavone results in increased activity of CYP3A4 protein] which results in increased metabolism of Midazolam; [galangin results in increased activity of CYP3A4 protein] which results in increased metabolism of Midazolam; [Ketoconazole results in decreased activity of CYP3A4 protein] which results in decreased hydroxylation of Midazolam; [Ketoconazole results in decreased activity of CYP3A4 protein] which results in decreased metabolism of Midazolam; [L 754394 results in decreased activity of CYP3A4 protein] which results in decreased hydroxylation of Midazolam; [nobiletin results in increased activity of CYP3A4 protein] which results in increased metabolism of Midazolam; [Pioglitazone results in increased expression of CYP3A4 protein] which results in decreased abundance of Midazolam; [Rifampin results in increased expression of CYP3A4 protein] which results in decreased abundance of Midazolam; [sinensetin analog results in increased activity of CYP3A4 protein] which results in increased metabolism of Midazolam; [sinensetin results in increased activity of CYP3A4 protein] which results in increased metabolism of Midazolam; [tangeretin results in increased activity of CYP3A4 protein] which results in increased metabolism of Midazolam; acacetin inhibits the reaction [[CYP3A4 protein results in increased oxidation of Midazolam] which results in increased chemical synthesis of 4-hydroxymidazolam]; acacetin promotes the reaction [[CYP3A4 protein results in increased oxidation of Midazolam] which results in increased chemical synthesis of 1-hydroxymethylmidazolam]; allyl methyl disulfide inhibits the reaction [CYP3A4 protein results in increased hydroxylation of Midazolam]; Amiodarone inhibits the reaction [CYP3A4 protein results in increased hydroxylation of Midazolam]; Apigenin inhibits the reaction [[CYP3A4 protein results in increased oxidation of Midazolam] which results in increased chemical synthesis of 4-hydroxymidazolam]; Apigenin promotes the reaction [[CYP3A4 protein results in increased oxidation of Midazolam] which results in increased chemical synthesis of 1-hydroxymethylmidazolam]; Atorvastatin inhibits the reaction [CYP3A4 protein affects the metabolism of Midazolam]; bufalin promotes the reaction [CYP3A4 protein results in increased metabolism of Midazolam]; bufogenin promotes the reaction [CYP3A4 protein results in increased metabolism of Midazolam]; caryophyllene inhibits the reaction [CYP3A4 protein results in increased hydroxylation of Midazolam]; cinobufagin promotes the reaction [CYP3A4 protein results in increased metabolism of Midazolam]; citral inhibits the reaction [CYP3A4 protein results in increased hydroxylation of Midazolam]; Curcumin inhibits the reaction [CYP3A4 protein results in increased hydroxylation of Midazolam]; CYP3A4 protein inhibits the reaction [Rifampin results in decreased hydroxylation of Midazolam]; deoxyelephantopin inhibits the reaction [CYP3A4 protein results in increased hydroxylation of Midazolam]; Diltiazem inhibits the reaction [CYP3A4 protein results in increased hydroxylation of Midazolam]; Eucalyptol inhibits the reaction [CYP3A4 protein results in increased hydroxylation of Midazolam]; flavanone inhibits the reaction [[CYP3A4 protein results in increased oxidation of Midazolam] which results in increased chemical synthesis of 4-hydroxymidazolam]; flavanone promotes the reaction [[CYP3A4 protein results in increased oxidation of Midazolam] which results in increased chemical synthesis of 1-hydroxymethylmidazolam]; flavone inhibits the reaction [[CYP3A4 protein results in increased oxidation of Midazolam] which results in increased chemical synthesis of 4-hydroxymidazolam]; flavone promotes the reaction [[CYP3A4 protein results in increased oxidation of Midazolam] which results in increased chemical synthesis of 1-hydroxymethylmidazolam]; Fluvastatin inhibits the reaction [CYP3A4 protein affects the metabolism of Midazolam]; fructus schizandrae, radix ginseng, radix ophiopogonis drug combination affects the reaction [CYP3A4 protein affects the metabolism of Midazolam]; Fusidic Acid inhibits the reaction [CYP3A4 protein results in increased hydroxylation of Midazolam]; galangin inhibits the reaction [[CYP3A4 protein results in increased oxidation of Midazolam] which results in increased chemical synthesis of 4-hydroxymidazolam]; galangin promotes the reaction [[CYP3A4 protein results in increased oxidation of Midazolam] which results in increased chemical synthesis of 1-hydroxymethylmidazolam]; gingerol inhibits the reaction [CYP3A4 protein results in increased hydroxylation of Midazolam]; Ketoconazole inhibits the reaction [CYP3A4 protein results in decreased abundance of Midazolam]; Ketoconazole inhibits the reaction [CYP3A4 protein results in increased hydroxylation of Midazolam]; Ketoconazole inhibits the reaction [CYP3A4 protein results in increased metabolism of Midazolam]; Limonene inhibits the reaction [CYP3A4 protein results in increased hydroxylation of Midazolam]; Midazolam inhibits the reaction [CYP3A4 protein results in decreased methylation of Etoposide]; Midazolam inhibits the reaction [CYP3A4 protein results in decreased methylation of Teniposide]; Midazolam inhibits the reaction [CYP3A4 protein results in increased oxidation of 7-benzyloxy-4-trifluoromethylcoumarin]; Mifepristone inhibits the reaction [CYP3A4 protein results in increased hydroxylation of Midazolam]; Mifepristone inhibits the reaction [CYP3A4 protein results in increased metabolism of Midazolam]; muscone promotes the reaction [CYP3A4 protein results in increased metabolism of Midazolam]; Oleanolic Acid inhibits the reaction [CYP3A4 protein results in increased metabolism of Midazolam]; Pantoprazole inhibits the reaction [CYP3A4 protein results in increased hydroxylation of Midazolam]; potassium ferricyanide inhibits the reaction [Diltiazem inhibits the reaction [CYP3A4 protein results in increased hydroxylation of Midazolam]]; potassium ferricyanide promotes the reaction [Diltiazem inhibits the reaction [CYP3A4 protein results in increased hydroxylation of Midazolam]]; rabeprazole-thioether inhibits the reaction [CYP3A4 protein results in increased hydroxylation of Midazolam]; Rifampin inhibits the reaction [CYP3A4 protein results in increased hydroxylation of Midazolam]; Rifampin promotes the reaction [CYP3A4 protein results in increased hydroxylation of Midazolam]; shexiang baoxin promotes the reaction [CYP3A4 protein results in increased metabolism of Midazolam]; Troleandomycin inhibits the reaction [CYP3A4 protein results in increased hydroxylation of Midazolam]; Troleandomycin inhibits the reaction [CYP3A4 protein results in increased metabolism of Midazolam]; Verapamil inhibits the reaction [CYP3A4 protein results in increased metabolism of Midazolam]; YM 758 inhibits the reaction [CYP3A4 protein results in increased metabolism of Midazolam]; zafirlukast inhibits the reaction [CYP3A4 protein results in increased metabolism of Midazolam]
shikonin inhibits the reaction [CYP3A2 protein results in increased hydroxylation of Midazolam]
CTD PMID:8114683 PMID:10997946 PMID:11911841 PMID:12401345 PMID:12433797 More... NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 increases hydroxylation EXP CYP3A23-3A1 protein results in increased hydroxylation of Midazolam CTD PMID:11911841 NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 affects metabolic processing
increases metabolic processing
multiple interactions
increases hydroxylation
ISO
EXP
CYP3A5 gene polymorphism affects the metabolism of Midazolam; CYP3A5 protein affects the metabolism of Midazolam
CYP3A5 protein results in increased metabolism of Midazolam
fructus schizandrae, radix ginseng, radix ophiopogonis drug combination affects the reaction [CYP3A5 protein affects the metabolism of Midazolam]
CYP3A5 protein results in increased hydroxylation of Midazolam
CTD PMID:15383492 PMID:15499178 PMID:15801540 PMID:15900284 PMID:19557931 More... NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422
JBrowse link
G Gabra4 gamma-aminobutyric acid type A receptor subunit alpha 4 increases expression ISO Midazolam results in increased expression of GABRA4 mRNA CTD PMID:16733821 NCBI chr14:36,590,782...36,667,724
Ensembl chr14:36,590,782...36,665,844
JBrowse link
G Gabra6 gamma-aminobutyric acid type A receptor subunit alpha6 decreases response to substance ISO GABRA6 protein mutant form results in decreased susceptibility to Midazolam CTD PMID:12031754 NCBI chr10:26,810,411...26,825,768
Ensembl chr10:26,810,423...26,825,769
JBrowse link
G Gabrb3 gamma-aminobutyric acid type A receptor subunit beta 3 increases response to substance ISO GABRB3 protein results in increased susceptibility to Midazolam CTD PMID:9523823 NCBI chr 1:108,467,047...108,702,522
Ensembl chr 1:108,296,124...108,698,961
JBrowse link
G Gabre gamma-aminobutyric acid type A receptor subunit epsilon decreases response to substance EXP GABRE protein results in decreased susceptibility to Midazolam CTD PMID:11691872 NCBI chr  X:150,060,035...150,078,773
Ensembl chr  X:150,060,040...150,078,693
JBrowse link
G Gabrg2 gamma-aminobutyric acid type A receptor subunit gamma 2 affects response to substance
affects binding
ISO GABRG2 protein alternative form affects the susceptibility to Midazolam
GABRG2 protein mutant form binds to Midazolam
CTD PMID:10880692 NCBI chr10:26,376,805...26,463,680
Ensembl chr10:26,374,694...26,464,346
JBrowse link
G Gast gastrin multiple interactions EXP [fluanisone co-treated with Fentanyl co-treated with Midazolam] inhibits the reaction [GAST protein results in increased secretion of Histamine] CTD PMID:10864877 NCBI chr10:85,264,832...85,269,393
Ensembl chr10:85,264,832...85,267,496
JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A affects response to substance ISO GRIN2A protein affects the susceptibility to Midazolam CTD PMID:15731593 NCBI chr10:5,630,684...6,043,341
Ensembl chr10:5,631,369...6,044,637
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity
multiple interactions
ISO Midazolam results in increased activity of NR1I2 protein
NR1I2 gene promotes the reaction [Rifampin results in increased metabolism of Midazolam]
CTD PMID:18799805 PMID:20080160 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 decreases metabolic processing ISO NR1I3 gene mutant form results in decreased metabolism of Midazolam CTD PMID:27434302 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
JBrowse link
G Star steroidogenic acute regulatory protein increases expression ISO Midazolam results in increased expression of STAR protein CTD PMID:19857560 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672
JBrowse link
G Syn1 synapsin I decreases expression EXP Midazolam results in decreased expression of SYN1 protein CTD PMID:21920406 NCBI chr  X:1,172,208...1,227,400
Ensembl chr  X:1,172,208...1,227,396
JBrowse link
G Trh thyrotropin releasing hormone multiple interactions EXP Midazolam inhibits the reaction [TRH protein modified form binds to TRHR protein] CTD PMID:2845442 NCBI chr 4:124,742,111...124,777,094
Ensembl chr 4:124,742,111...124,744,637
JBrowse link
G Trhr thyrotropin releasing hormone receptor multiple interactions EXP Midazolam inhibits the reaction [TRH protein modified form binds to TRHR protein] CTD PMID:2845442 NCBI chr 7:75,348,672...75,393,310
Ensembl chr 7:75,348,672...75,393,309
JBrowse link
G Tspo translocator protein increases expression
affects binding
ISO
EXP
Midazolam results in increased expression of TSPO protein
Midazolam binds to TSPO protein
CTD PMID:7603229 PMID:19857560 NCBI chr 7:114,720,188...114,730,450
Ensembl chr 7:114,720,188...114,730,450
JBrowse link
nimetazepam term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 multiple interactions ISO CYP3A4 protein affects the reaction [nimetazepam results in increased activity of CASP3 protein] CTD PMID:19005028 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp7 caspase 7 multiple interactions ISO CYP3A4 protein affects the reaction [nimetazepam results in increased activity of CASP7 protein] CTD PMID:19005028 NCBI chr 1:255,437,195...255,476,737
Ensembl chr 1:255,437,172...255,476,729
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions ISO CYP3A4 protein affects the reaction [nimetazepam results in increased activity of CASP3 protein]; CYP3A4 protein affects the reaction [nimetazepam results in increased activity of CASP7 protein]; CYP3A4 protein results in increased metabolism of and results in increased activity of nimetazepam CTD PMID:19005028 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO nimetazepam inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268
JBrowse link
nitrazepam term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1c1 aldo-keto reductase family 1, member C1 decreases activity ISO Nitrazepam results in decreased activity of AKR1C4 protein CTD PMID:11995921 NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326
JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 decreases activity ISO Nitrazepam results in decreased activity of AKR1C2 protein CTD PMID:11995921 NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764
JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 decreases activity ISO Nitrazepam results in decreased activity of AKR1C3 protein CTD PMID:11995921 NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873
JBrowse link
G Casp3 caspase 3 multiple interactions ISO CYP3A4 protein affects the reaction [Nitrazepam results in increased activity of CASP3 protein] CTD PMID:19005028 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp7 caspase 7 multiple interactions ISO CYP3A4 protein affects the reaction [Nitrazepam results in increased activity of CASP7 protein] CTD PMID:19005028 NCBI chr 1:255,437,195...255,476,737
Ensembl chr 1:255,437,172...255,476,729
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions ISO CYP3A4 protein affects the reaction [Nitrazepam results in increased activity of CASP3 protein]; CYP3A4 protein affects the reaction [Nitrazepam results in increased activity of CASP7 protein]; CYP3A4 protein results in increased metabolism of and results in increased activity of Nitrazepam CTD PMID:19005028 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO Nitrazepam binds to and results in increased activity of ESR1 protein CTD PMID:25752796 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
nitroglycerin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acat1 acetyl-CoA acetyltransferase 1 increases expression EXP Nitroglycerin results in increased expression of ACAT1 mRNA CTD PMID:12102619 NCBI chr 8:53,979,813...54,008,861
Ensembl chr 8:53,979,813...54,008,855
JBrowse link
G Actb actin, beta decreases expression EXP Nitroglycerin results in decreased expression of ACTB mRNA CTD PMID:12102619 NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 decreases expression EXP Nitroglycerin results in decreased expression of ALDH1A1 mRNA CTD PMID:12102619 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member multiple interactions
decreases activity
increases response to substance
decreases expression
affects metabolic processing
affects response to substance
ISO
EXP
[1-aminocyclopropanol analog results in decreased activity of ALDH2 protein] which results in decreased metabolism of Nitroglycerin; [Chloral Hydrate results in decreased activity of ALDH2 protein] which results in decreased metabolism of Nitroglycerin; [Cyanamide results in decreased activity of ALDH2 protein] which results in decreased metabolism of Nitroglycerin; Acetylcysteine inhibits the reaction [Nitroglycerin results in decreased activity of ALDH2 protein]; ALDH2 protein affects the reaction [Nitroglycerin results in decreased abundance of Cyclic GMP]
ALDH2 protein affects the reaction [Ascorbic Acid deficiency results in decreased susceptibility to Nitroglycerin]
ALDH2 protein results in increased susceptibility to Nitroglycerin
Nitroglycerin results in decreased expression of ALDH2 mRNA; Nitroglycerin results in decreased expression of ALDH2 protein
ALDH2 protein affects the metabolism of and results in increased activity of Nitroglycerin; ALDH2 protein affects the reaction [Nitroglycerin results in increased abundance of Reactive Oxygen Species]; Hemin inhibits the reaction [Nitroglycerin results in decreased activity of ALDH2 protein]
ALDH2 protein affects the metabolism of Nitroglycerin
ALDH2 gene polymorphism affects the susceptibility to Nitroglycerin; ALDH2 protein affects the susceptibility to Nitroglycerin; ALDH2 protein polymorphism affects the susceptibility to Nitroglycerin
CTD PMID:15331769 PMID:16440063 PMID:17092343 PMID:17493633 PMID:17541025 More... NCBI chr12:34,949,549...34,982,527 JBrowse link
G Alox15 arachidonate 15-lipoxygenase decreases expression EXP Nitroglycerin results in decreased expression of ALOX15 mRNA CTD PMID:12102619 NCBI chr10:55,060,169...55,068,885
Ensembl chr10:55,060,412...55,068,874
JBrowse link
G Ap2m1 adaptor related protein complex 2 subunit mu 1 increases expression EXP Nitroglycerin results in increased expression of AP2M1 mRNA CTD PMID:12102619 NCBI chr11:80,355,307...80,364,218
Ensembl chr11:80,328,041...80,364,140
JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 increases expression EXP Nitroglycerin results in increased expression of APEX1 mRNA CTD PMID:12102619 NCBI chr15:24,144,595...24,146,785
Ensembl chr15:24,144,362...24,146,785
JBrowse link
G Apoa1 apolipoprotein A1 decreases expression EXP Nitroglycerin results in decreased expression of APOA1 mRNA CTD PMID:12102619 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
JBrowse link
G Arl2 ADP-ribosylation factor like GTPase 2 increases expression EXP Nitroglycerin results in increased expression of ARL2 mRNA CTD PMID:12102619 NCBI chr 1:203,434,129...203,446,156
Ensembl chr 1:203,434,129...203,446,119
JBrowse link
G Atp5f1a ATP synthase F1 subunit alpha decreases expression EXP Nitroglycerin results in decreased expression of ATP5F1A mRNA CTD PMID:12102619 NCBI chr18:71,292,406...71,300,342
Ensembl chr18:71,292,374...71,300,794
JBrowse link
G B2m beta-2 microglobulin affects expression ISO Nitroglycerin affects the expression of B2M protein CTD PMID:8350464 NCBI chr 3:109,095,740...109,101,764
Ensembl chr 3:109,095,729...109,101,766
JBrowse link
G Bckdhb branched chain keto acid dehydrogenase E1 subunit beta decreases expression EXP Nitroglycerin results in decreased expression of BCKDHB mRNA CTD PMID:12102619 NCBI chr 8:84,845,264...85,027,812
Ensembl chr 8:84,845,264...85,027,812
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression EXP Nitroglycerin results in decreased expression of BCL2 protein CTD PMID:17678976 NCBI chr13:22,689,783...22,853,920 JBrowse link
G C3 complement C3 increases expression ISO Nitroglycerin results in increased expression of C3 protein alternative form CTD PMID:10884648 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429
JBrowse link
G Calca calcitonin-related polypeptide alpha multiple interactions
increases expression
affects expression
EXP
ISO
Capsaicin inhibits the reaction [Nitroglycerin results in increased expression of CALCA mRNA]; Dexamethasone inhibits the reaction [Nitroglycerin results in increased expression of CALCA mRNA]; Ergotamine inhibits the reaction [Nitroglycerin results in increased expression of CALCA protein]; Methylene Blue inhibits the reaction [Nitroglycerin results in increased expression of CALCA mRNA]; NOS2 protein affects the reaction [Nitroglycerin results in increased expression of CALCA mRNA]; pimagedine inhibits the reaction [Nitroglycerin results in increased expression of CALCA mRNA]; Plant Oils inhibits the reaction [Nitroglycerin results in increased expression of CALCA protein]
Nitroglycerin results in increased expression of CALCA mRNA; Nitroglycerin results in increased expression of CALCA protein
Nitroglycerin affects the expression of CALCA protein
CTD PMID:11919648 PMID:14659530 PMID:14729435 PMID:19121572 NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105
JBrowse link
G Calm2 calmodulin 2 increases expression EXP Nitroglycerin results in increased expression of CALM2 mRNA CTD PMID:12102619 NCBI chr 6:7,091,624...7,104,284
Ensembl chr 6:7,091,567...7,104,287
JBrowse link
G Capn2 calpain 2 decreases expression EXP Nitroglycerin results in decreased expression of CAPN2 mRNA CTD PMID:12102619 NCBI chr13:94,150,244...94,200,969
Ensembl chr13:94,150,240...94,200,969
JBrowse link
G Casp1 caspase 1 multiple interactions ISO Nitroglycerin results in increased cleavage of and results in increased activity of CASP1 protein CTD PMID:12105852 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
JBrowse link
G Casp3 caspase 3 decreases expression
multiple interactions
ISO Nitroglycerin results in decreased expression of CASP3 protein modified form
Nitroglycerin results in increased cleavage of and results in increased activity of CASP3 protein
CTD PMID:12105852 PMID:17322376 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Cat catalase multiple interactions EXP Nitroglycerin results in increased expression of and results in increased activity of CAT protein CTD PMID:12860443 PMID:14732477 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cd3d CD3d molecule increases expression EXP Nitroglycerin results in increased expression of CD3D mRNA CTD PMID:12102619 NCBI chr 8:45,287,803...45,293,342
Ensembl chr 8:45,288,749...45,301,809
JBrowse link
G Cd5 Cd5 molecule decreases expression EXP Nitroglycerin results in decreased expression of CD5 mRNA CTD PMID:12102619 NCBI chr 1:207,365,337...207,386,313
Ensembl chr 1:207,365,337...207,386,313
JBrowse link
G Cd53 Cd53 molecule decreases expression EXP Nitroglycerin results in decreased expression of CD53 mRNA CTD PMID:12102619 NCBI chr 2:194,352,139...194,399,668
Ensembl chr 2:194,352,139...194,399,657
JBrowse link
G Cdc37 cell division cycle 37, HSP90 cochaperone increases expression EXP Nitroglycerin results in increased expression of CDC37 mRNA CTD PMID:12102619 NCBI chr 8:19,677,400...19,690,761
Ensembl chr 8:19,671,938...19,690,809
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases expression EXP Nitroglycerin results in increased expression of CDKN1B mRNA CTD PMID:12102619 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
JBrowse link
G Celf2 CUGBP, Elav-like family member 2 increases expression EXP Nitroglycerin results in increased expression of CELF2 mRNA CTD PMID:12102619 NCBI chr17:70,904,462...71,729,072
Ensembl chr17:71,210,853...71,728,333
JBrowse link
G Ckb creatine kinase B decreases expression EXP Nitroglycerin results in decreased expression of CKB mRNA CTD PMID:12102619 NCBI chr 6:130,729,420...130,732,301
Ensembl chr 6:130,729,423...130,732,315
JBrowse link
G Clu clusterin decreases expression EXP Nitroglycerin results in decreased expression of CLU mRNA CTD PMID:12102619 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315
JBrowse link
G Cnr1 cannabinoid receptor 1 multiple interactions EXP Nitroglycerin affects the reaction [glyceryl 2-arachidonate affects the activity of CNR1 protein] CTD PMID:16775503 NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099
JBrowse link
G Cp ceruloplasmin decreases expression EXP Nitroglycerin results in decreased expression of CP mRNA CTD PMID:12102619 NCBI chr 2:102,439,433...102,498,075
Ensembl chr 2:102,439,624...102,498,075
JBrowse link
G Crip2 cysteine-rich protein 2 decreases expression EXP Nitroglycerin results in decreased expression of CRIP2 mRNA CTD PMID:12102619 NCBI chr 6:132,221,120...132,226,066
Ensembl chr 6:132,221,082...132,226,065
JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions
decreases localization
ISO 4-(2-aminoethyl)benzenesulfonylfluoride inhibits the reaction [Nitroglycerin results in decreased localization of CTNNB1 protein]; 4-(2-aminoethyl)benzenesulfonylfluoride inhibits the reaction [Nitroglycerin results in increased degradation of and results in decreased activity of CTNNB1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Nitroglycerin results in increased degradation of CTNNB1 protein]; Nitroglycerin inhibits the reaction [CTNNB1 protein binds to TCF4 protein]; Nitroglycerin results in decreased phosphorylation of and results in increased nitrosation of and results in increased degradation of and results in decreased activity of CTNNB1 protein; Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [Nitroglycerin inhibits the reaction [CTNNB1 protein binds to TCF4 protein]]; Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [Nitroglycerin results in decreased localization of CTNNB1 protein]; Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [Nitroglycerin results in increased degradation of and results in decreased activity of CTNNB1 protein] CTD PMID:17030184 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Ctsd cathepsin D decreases expression EXP Nitroglycerin results in decreased expression of CTSD mRNA CTD PMID:12102619 NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488
JBrowse link
G Cybb cytochrome b-245 beta chain multiple interactions
decreases expression
increases expression
decreases response to substance
ISO
EXP
CYBB gene mutant form inhibits the reaction [Nitroglycerin results in decreased susceptibility to Acetylcholine]; Rosuvastatin Calcium inhibits the reaction [Nitroglycerin results in increased expression of CYBB mRNA]
Nitroglycerin results in decreased expression of CYBB mRNA
CYBB gene mutant form results in decreased susceptibility to Nitroglycerin
CTD PMID:16633368 PMID:17493633 PMID:18522491 NCBI chr  X:13,360,583...13,392,517
Ensembl chr  X:13,359,430...13,392,586
JBrowse link
G Cyp11b3 cytochrome P450, family 11, subfamily b, polypeptide 3 decreases expression EXP Nitroglycerin results in decreased expression of CYP11B2 mRNA CTD PMID:12102619 NCBI chr 7:106,808,559...106,814,048
Ensembl chr 7:106,808,559...106,814,048
JBrowse link
G Cyp2b15 cytochrome P450, family 2, subfamily b, polypeptide 15 decreases expression EXP Nitroglycerin results in decreased expression of CYP2B15 mRNA CTD PMID:12102619 NCBI chr 1:82,094,188...82,106,492
Ensembl chr 1:82,094,180...82,106,492
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases expression EXP Nitroglycerin results in increased expression of CYP2E1 mRNA CTD PMID:12102619 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Defb4 defensin beta 4 decreases expression EXP Nitroglycerin results in decreased expression of DEFB4 mRNA CTD PMID:12102619 NCBI chr16:70,650,472...70,653,665
Ensembl chr16:70,650,472...70,653,665
JBrowse link
G Dhcr7 7-dehydrocholesterol reductase decreases expression EXP Nitroglycerin results in decreased expression of DHCR7 mRNA CTD PMID:12102619 NCBI chr 1:199,015,081...199,031,055
Ensembl chr 1:199,015,081...199,031,055
JBrowse link
G Dync1i1 dynein cytoplasmic 1 intermediate chain 1 decreases expression EXP Nitroglycerin results in decreased expression of DYNC1I1 mRNA CTD PMID:12102619 NCBI chr 4:33,852,597...34,166,159
Ensembl chr 4:33,852,927...34,166,149
JBrowse link
G Dyrk1a dual specificity tyrosine phosphorylation regulated kinase 1A decreases expression EXP Nitroglycerin results in decreased expression of DYRK1A mRNA CTD PMID:12102619 NCBI chr11:33,890,706...34,009,420
Ensembl chr11:33,890,490...34,009,420
JBrowse link
G Edn1 endothelin 1 decreases expression
increases expression
multiple interactions
ISO
EXP
Nitroglycerin results in decreased expression of EDN1 mRNA
Nitroglycerin results in increased expression of EDN1 protein
Nitroglycerin results in decreased expression of EDN1 mRNA; Nitroglycerin results in decreased expression of EDN1 protein
Losartan inhibits the reaction [Nitroglycerin results in increased expression of EDN1 protein]
CTD PMID:11751199 PMID:12206003 PMID:12901495 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Elane elastase, neutrophil expressed increases expression ISO Nitroglycerin results in increased expression of ELANE protein CTD PMID:10884648 NCBI chr 7:9,817,251...9,819,174
Ensembl chr 7:9,817,252...9,819,100
JBrowse link
G Eln elastin increases expression EXP Nitroglycerin results in increased expression of ELN mRNA CTD PMID:12187120 NCBI chr12:21,968,544...22,011,929
Ensembl chr12:21,968,544...22,011,928
JBrowse link
G Faah fatty acid amide hydrolase increases activity
multiple interactions
EXP Nitroglycerin results in increased activity of FAAH protein
Nitroglycerin promotes the reaction [FAAH protein results in increased chemical synthesis of Arachidonic Acid]; Nitroglycerin promotes the reaction [FAAH protein results in increased degradation of anandamide]
CTD PMID:19515121 NCBI chr 5:129,479,774...129,499,018 JBrowse link
G Fas Fas cell surface death receptor multiple interactions ISO Nitroglycerin results in increased expression of and results in increased localization of FAS protein CTD PMID:12105852 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 increases expression EXP Nitroglycerin results in increased expression of FGFR2 mRNA CTD PMID:12102619 NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626
JBrowse link
G Fmo1 flavin containing dimethylaniline monoxygenase 1 decreases expression EXP Nitroglycerin results in decreased expression of FMO1 mRNA CTD PMID:12102619 NCBI chr13:75,182,184...75,214,439
Ensembl chr13:75,182,176...75,214,647
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions
ISO
EXP
Nitroglycerin results in increased expression of FOS protein
anandamide inhibits the reaction [Nitroglycerin results in increased expression of FOS protein]; Ergotamine inhibits the reaction [Nitroglycerin results in increased expression of FOS protein]; Plant Oils inhibits the reaction [Nitroglycerin results in increased expression of FOS protein]; Pregabalin inhibits the reaction [Nitroglycerin results in increased expression of FOS protein]
CTD PMID:7552308 PMID:10426492 PMID:16897600 PMID:18761334 PMID:19121572 More... NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Gchfr GTP cyclohydrolase I feedback regulator decreases expression EXP Nitroglycerin results in decreased expression of GCHFR mRNA CTD PMID:12102619 NCBI chr 3:106,158,046...106,162,080
Ensembl chr 3:106,159,394...106,162,080
JBrowse link
G Gnb3 G protein subunit beta 3 affects response to substance ISO GNB3 protein affects the susceptibility to Nitroglycerin CTD PMID:14586390 NCBI chr 4:157,639,468...157,645,171
Ensembl chr 4:157,639,469...157,645,173
JBrowse link
G Gng7 G protein subunit gamma 7 decreases expression EXP Nitroglycerin results in decreased expression of GNG7 mRNA CTD PMID:12102619 NCBI chr 7:8,697,458...8,761,239
Ensembl chr 7:8,697,521...8,761,240
JBrowse link
G Gpx1 glutathione peroxidase 1 decreases response to substance ISO GPX1 gene mutant form results in decreased susceptibility to Nitroglycerin CTD PMID:24296279 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Grk6 G protein-coupled receptor kinase 6 decreases expression EXP Nitroglycerin results in decreased expression of GRK6 mRNA CTD PMID:12102619 NCBI chr17:9,177,018...9,192,644
Ensembl chr17:9,177,019...9,192,644
JBrowse link
G Grn granulin precursor decreases expression EXP Nitroglycerin results in decreased expression of GRN mRNA CTD PMID:12102619 NCBI chr10:87,387,672...87,393,777
Ensembl chr10:87,387,638...87,393,775
JBrowse link
G Gsn gelsolin increases expression EXP Nitroglycerin results in increased expression of GSN mRNA CTD PMID:12187120 NCBI chr 3:18,585,166...18,638,404
Ensembl chr 3:18,585,172...18,638,402
JBrowse link
G Gsta1 glutathione S-transferase alpha 1 affects metabolic processing EXP GSTA3 protein affects the metabolism of Nitroglycerin CTD PMID:8968379 NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121
JBrowse link
G Gsta2 glutathione S-transferase alpha 2 decreases expression EXP Nitroglycerin results in decreased expression of GSTA2 mRNA CTD PMID:12102619 NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798
JBrowse link
G Gstm2 glutathione S-transferase mu 2 affects metabolic processing EXP GSTM2 protein affects the metabolism of Nitroglycerin CTD PMID:8968379 NCBI chr 2:195,624,015...195,628,774 JBrowse link
G Gtf3c1 general transcription factor IIIC subunit 1 increases expression EXP Nitroglycerin results in increased expression of GTF3C1 mRNA CTD PMID:12102619 NCBI chr 1:180,203,995...180,270,201
Ensembl chr 1:180,203,995...180,270,201
JBrowse link
G Gucy1a1 guanylate cyclase 1 soluble subunit alpha 1 increases expression EXP Nitroglycerin results in increased expression of GUCY1A1 mRNA; Nitroglycerin results in increased expression of GUCY1A1 protein CTD PMID:11331261 NCBI chr 2:167,418,615...167,482,293
Ensembl chr 2:167,418,640...167,481,671
JBrowse link
G Gucy1b1 guanylate cyclase 1 soluble subunit beta 1 increases expression ISO
EXP
Nitroglycerin results in increased expression of GUCY1B1 protein
Nitroglycerin results in increased expression of GUCY1B1 mRNA; Nitroglycerin results in increased expression of GUCY1B1 protein
CTD PMID:11331261 PMID:11742226 PMID:17541025 NCBI chr 2:167,348,824...167,398,983
Ensembl chr 2:167,348,825...167,398,916
JBrowse link
G Hbb hemoglobin subunit beta increases expression EXP Nitroglycerin results in increased expression of HBB mRNA CTD PMID:12187120 NCBI chr 1:158,250,421...158,251,832 JBrowse link
G Hdc histidine decarboxylase decreases expression EXP Nitroglycerin results in decreased expression of HDC mRNA CTD PMID:12102619 NCBI chr 3:113,847,256...113,865,334
Ensembl chr 3:113,847,260...113,865,341
JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
ISO
EXP
Nitroglycerin results in increased expression of HMOX1 mRNA
[Hemin co-treated with Nitroglycerin] results in increased expression of HMOX1 mRNA; [Hemin co-treated with Nitroglycerin] results in increased expression of HMOX1 protein
CTD PMID:17092343 PMID:17470570 PMID:17541025 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hpn hepsin increases expression EXP Nitroglycerin results in increased expression of HPN mRNA CTD PMID:12102619 NCBI chr 1:86,337,085...86,352,785
Ensembl chr 1:86,337,087...86,352,811
JBrowse link
G Iapp islet amyloid polypeptide increases expression EXP Nitroglycerin results in increased expression of IAPP mRNA CTD PMID:12102619 NCBI chr 4:175,237,013...175,244,373
Ensembl chr 4:175,237,115...175,242,920
JBrowse link
G Id2 inhibitor of DNA binding 2 increases expression EXP Nitroglycerin results in increased expression of ID2 mRNA CTD PMID:12102619 NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400
JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 decreases expression EXP Nitroglycerin results in decreased expression of IDO1 protein CTD PMID:28659861 NCBI chr16:67,430,684...67,442,459
Ensembl chr16:67,430,578...67,442,730
JBrowse link
G Il1b interleukin 1 beta increases expression EXP Nitroglycerin results in increased expression of IL1B protein CTD PMID:11701602 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 increases expression ISO
EXP
Nitroglycerin results in increased expression of IL6 mRNA; Nitroglycerin results in increased expression of IL6 protein CTD PMID:11701602 PMID:17470570 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Jtb jumping translocation breakpoint increases expression EXP Nitroglycerin results in increased expression of JTB mRNA CTD PMID:12102619 NCBI chr 2:175,685,392...175,689,609
Ensembl chr 2:175,684,993...175,690,108
JBrowse link
G Kmo kynurenine 3-monooxygenase decreases expression EXP Nitroglycerin results in decreased expression of KMO protein CTD PMID:28659861 NCBI chr13:87,557,080...87,589,334
Ensembl chr13:87,557,286...87,588,881
JBrowse link
G Kng2 kininogen 2 decreases expression EXP Nitroglycerin results in decreased expression of KNG2 mRNA CTD PMID:12102619 NCBI chr11:77,913,876...77,936,247 JBrowse link
G Kynu kynureninase decreases expression EXP Nitroglycerin results in decreased expression of KYNU protein CTD PMID:28659861 NCBI chr 3:27,778,646...27,929,470
Ensembl chr 3:27,778,772...27,929,488
JBrowse link
G Maob monoamine oxidase B increases expression EXP Nitroglycerin results in increased expression of MAOB mRNA CTD PMID:12102619 NCBI chr  X:5,907,327...6,010,996
Ensembl chr  X:5,907,266...6,011,003
JBrowse link
G Mecr mitochondrial trans-2-enoyl-CoA reductase decreases expression EXP Nitroglycerin results in decreased expression of MECR mRNA CTD PMID:12102619 NCBI chr 5:144,029,684...144,056,373
Ensembl chr 5:144,029,731...144,055,863
JBrowse link
G Mgll monoglyceride lipase multiple interactions
increases activity
EXP Nitroglycerin promotes the reaction [MGLL protein results in increased chemical synthesis of Glycerol]; Nitroglycerin promotes the reaction [MGLL protein results in increased degradation of 2-oleoylglycerol]
Nitroglycerin results in increased activity of MGLL protein
CTD PMID:19515121 NCBI chr 4:121,192,187...121,294,187
Ensembl chr 4:121,192,195...121,294,179
JBrowse link
G Mmp2 matrix metallopeptidase 2 increases expression ISO Nitroglycerin results in increased expression of MMP2 mRNA CTD PMID:12084592 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Mmp7 matrix metallopeptidase 7 increases expression ISO Nitroglycerin results in increased expression of MMP7 mRNA CTD PMID:12084592 NCBI chr 8:4,848,186...4,855,908
Ensembl chr 8:4,848,186...4,855,902
JBrowse link
G Mmp9 matrix metallopeptidase 9 increases activity
increases expression
ISO Nitroglycerin results in increased activity of MMP9 protein
Nitroglycerin results in increased expression of MMP9 mRNA
CTD PMID:12084592 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Mpo myeloperoxidase decreases activity EXP Nitroglycerin results in decreased activity of MPO protein CTD PMID:8869312 NCBI chr10:72,594,458...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Mxi1 MAX interactor 1, dimerization protein increases expression EXP Nitroglycerin results in increased expression of MXI1 mRNA CTD PMID:12102619 NCBI chr 1:252,323,915...252,383,682
Ensembl chr 1:252,323,303...252,383,681
JBrowse link
G Myo9b myosin IXb decreases expression EXP Nitroglycerin results in decreased expression of MYO9B mRNA CTD PMID:12102619 NCBI chr16:17,945,379...18,030,114
Ensembl chr16:17,945,448...18,030,126
JBrowse link
G Ncam1 neural cell adhesion molecule 1 increases expression EXP Nitroglycerin results in increased expression of NCAM1 mRNA CTD PMID:12102619 NCBI chr 8:49,865,629...50,165,687
Ensembl chr 8:49,865,633...50,166,014
JBrowse link
G Ncf1 neutrophil cytosolic factor 1 decreases response to substance
multiple interactions
ISO NCF1 gene mutant form results in decreased susceptibility to Nitroglycerin
NCF1 gene mutant form inhibits the reaction [Nitroglycerin results in decreased susceptibility to Acetylcholine]
CTD PMID:18522491 NCBI chr12:22,485,382...22,494,647
Ensembl chr12:22,485,451...22,494,646
JBrowse link
G Ndufa5 NADH:ubiquinone oxidoreductase subunit A5 decreases expression EXP Nitroglycerin results in decreased expression of NDUFA5 mRNA CTD PMID:12102619 NCBI chr 4:52,997,327...53,005,685
Ensembl chr 4:52,995,546...53,005,598
JBrowse link
G Nkx2-1 NK2 homeobox 1 decreases expression EXP Nitroglycerin results in decreased expression of NKX2-1 mRNA CTD PMID:12102619 NCBI chr 6:73,996,601...74,001,483
Ensembl chr 6:73,996,601...73,999,791
JBrowse link
G Nnat neuronatin increases expression EXP Nitroglycerin results in increased expression of NNAT mRNA CTD PMID:12102619 NCBI chr 3:146,225,941...146,228,868
Ensembl chr 3:146,226,407...146,228,834
JBrowse link
G Nos1 nitric oxide synthase 1 multiple interactions
increases expression
EXP acetylsalicylic acid lysinate inhibits the reaction [Nitroglycerin results in increased expression of NOS1 protein]; Sumatriptan inhibits the reaction [Nitroglycerin results in increased expression of NOS1 protein] CTD PMID:14510930 PMID:15154853 NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945
JBrowse link
G Nos2 nitric oxide synthase 2 decreases expression
multiple interactions
increases expression
ISO
EXP
Nitroglycerin results in decreased expression of NOS2 mRNA
NOS2 protein affects the reaction [Nitroglycerin results in increased expression of CALCA mRNA]
Nitroglycerin results in increased expression of NOS2 mRNA; Nitroglycerin results in increased expression of NOS2 protein
Nitroglycerin results in decreased expression of NOS2 protein
CTD PMID:11701602 PMID:12206003 PMID:14729435 PMID:14732477 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nos3 nitric oxide synthase 3 multiple interactions
increases expression
EXP [Nitroglycerin co-treated with Hemin] results in increased expression of NOS3 mRNA; Nitroglycerin promotes the reaction [[Calcimycin results in increased activity of NOS3 protein] which results in increased abundance of Superoxides]
Nitroglycerin results in increased expression of NOS3 mRNA; Nitroglycerin results in increased expression of NOS3 protein
CTD PMID:10625313 PMID:12860443 PMID:14732477 PMID:17541025 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
JBrowse link
G Nox1 NADPH oxidase 1 decreases expression EXP Nitroglycerin results in decreased expression of NOX1 mRNA CTD PMID:17493633 NCBI chr  X:97,279,058...97,332,291
Ensembl chr  X:97,279,056...97,302,236
JBrowse link
G Nox4 NADPH oxidase 4 decreases expression EXP Nitroglycerin results in decreased expression of NOX4 mRNA CTD PMID:17493633 NCBI chr 1:140,900,886...141,078,844
Ensembl chr 1:140,901,097...141,077,406
JBrowse link
G Npy neuropeptide Y increases expression EXP Nitroglycerin results in increased expression of NPY protein CTD PMID:10426492 NCBI chr 4:78,881,294...78,888,495
Ensembl chr 4:78,881,264...78,888,495
JBrowse link
G Paics phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase increases expression EXP Nitroglycerin results in increased expression of PAICS mRNA CTD PMID:12102619 NCBI chr14:31,199,086...31,232,731
Ensembl chr14:31,173,541...31,232,635
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 decreases expression ISO Nitroglycerin results in decreased expression of PARP1 protein alternative form CTD PMID:17322376 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pcsk1n proprotein convertase subtilisin/kexin type 1 inhibitor decreases expression EXP Nitroglycerin results in decreased expression of PCSK1N mRNA CTD PMID:12102619 NCBI chr  X:14,580,036...14,583,478
Ensembl chr  X:14,580,038...14,583,566
JBrowse link
G Pde1a phosphodiesterase 1A increases expression
multiple interactions
EXP Nitroglycerin results in increased expression of PDE1A mRNA; Nitroglycerin results in increased expression of PDE1A protein
PDE1A protein inhibits the reaction [Nitroglycerin results in increased abundance of Cyclic GMP]
CTD PMID:11696475 NCBI chr 3:64,745,140...65,025,178
Ensembl chr 3:64,747,269...65,024,874
JBrowse link
G Pde2a phosphodiesterase 2A increases expression EXP Nitroglycerin results in increased expression of PDE2A mRNA CTD PMID:12102619 NCBI chr 1:155,823,590...155,915,434
Ensembl chr 1:155,813,180...155,915,434
JBrowse link
G Pla2g1b phospholipase A2 group IB increases expression EXP Nitroglycerin results in increased expression of PLA2G1B mRNA CTD PMID:12102619 NCBI chr12:41,142,193...41,151,967
Ensembl chr12:41,142,200...41,153,226
JBrowse link
G Plaur plasminogen activator, urokinase receptor increases expression EXP Nitroglycerin results in increased expression of PLAUR mRNA CTD PMID:12102619 NCBI chr 1:80,053,441...80,068,384
Ensembl chr 1:80,050,324...80,068,595
JBrowse link
G Pmp22 peripheral myelin protein 22 decreases expression EXP Nitroglycerin results in decreased expression of PMP22 mRNA CTD PMID:12102619 NCBI chr10:47,795,709...47,825,715
Ensembl chr10:47,795,709...47,825,714
JBrowse link
G Polr1b RNA polymerase I subunit B increases expression EXP Nitroglycerin results in increased expression of POLR1B mRNA CTD PMID:12102619 NCBI chr 3:116,333,910...116,358,385
Ensembl chr 3:116,333,889...116,358,379
JBrowse link
G Ppp2cb protein phosphatase 2 catalytic subunit beta decreases expression EXP Nitroglycerin results in decreased expression of PPP2CB mRNA CTD PMID:12102619 NCBI chr16:58,558,119...58,579,325
Ensembl chr16:58,558,122...58,579,576
JBrowse link
G Prkg1 protein kinase cGMP-dependent 1 decreases expression EXP Nitroglycerin results in decreased expression of PRKG1 protein CTD PMID:11331261 NCBI chr 1:228,409,883...229,638,794 JBrowse link
G Ptgds prostaglandin D2 synthase increases expression EXP Nitroglycerin results in increased expression of PTGDS mRNA CTD PMID:12102619 NCBI chr 3:8,281,899...8,284,833
Ensembl chr 3:8,281,899...8,284,833
JBrowse link
G Ptprr protein tyrosine phosphatase, receptor type, R increases expression EXP Nitroglycerin results in increased expression of PTPRR mRNA CTD PMID:12102619 NCBI chr 7:51,662,595...51,929,605
Ensembl chr 7:51,662,595...51,929,603
JBrowse link
G Rab40c Rab40c, member RAS oncogene family increases expression EXP Nitroglycerin results in increased expression of RAB40C mRNA CTD PMID:12187120 NCBI chr10:14,900,926...14,936,165
Ensembl chr10:14,900,929...14,936,557
JBrowse link
G Reg3b regenerating family member 3 beta increases expression EXP Nitroglycerin results in increased expression of REG3B mRNA CTD PMID:12102619 NCBI chr 4:110,861,775...110,865,015
Ensembl chr 4:110,861,775...110,865,015
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit increases localization
multiple interactions
EXP Nitroglycerin results in increased localization of RELA protein
Atorvastatin inhibits the reaction [Nitroglycerin results in increased localization of RELA protein]
CTD PMID:19733216 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Ren renin increases activity ISO Nitroglycerin results in increased activity of REN protein CTD PMID:9527094 NCBI chr13:44,796,260...44,807,491
Ensembl chr13:44,796,091...44,807,489
JBrowse link
G Rgs8 regulator of G-protein signaling 8 increases expression EXP Nitroglycerin results in increased expression of RGS8 mRNA CTD PMID:12102619 NCBI chr13:65,804,703...65,848,953
Ensembl chr13:65,804,797...65,846,807
JBrowse link
G Rheb Ras homolog, mTORC1 binding decreases expression EXP Nitroglycerin results in decreased expression of RHEB mRNA CTD PMID:12102619 NCBI chr 4:10,278,970...10,320,160
Ensembl chr 4:10,279,370...10,320,160
JBrowse link
G Rpl6 ribosomal protein L6 decreases expression EXP Nitroglycerin results in decreased expression of RPL6 mRNA CTD PMID:12102619 NCBI chr12:35,347,493...35,352,011
Ensembl chr12:35,347,497...35,351,921
JBrowse link
G Rps3a ribosomal protein S3a increases expression EXP Nitroglycerin results in increased expression of RPS3A mRNA CTD PMID:12102619 NCBI chr 2:171,524,685...171,529,054
Ensembl chr 2:171,524,500...171,529,055
JBrowse link
G Scgb1a1 secretoglobin family 1A member 1 decreases expression EXP Nitroglycerin results in decreased expression of SCGB1A1 mRNA CTD PMID:12102619 NCBI chr 1:205,977,060...205,980,610
Ensembl chr 1:205,977,060...205,980,610
JBrowse link
G Sdc4 syndecan 4 decreases expression EXP Nitroglycerin results in decreased expression of SDC4 mRNA CTD PMID:12102619 NCBI chr 3:153,154,888...153,173,576
Ensembl chr 3:153,154,896...153,173,580
JBrowse link
G Serpina3n serine (or cysteine) peptidase inhibitor, clade A, member 3N decreases expression EXP Nitroglycerin results in decreased expression of SERPINA3N mRNA CTD PMID:12102619 NCBI chr 6:123,323,632...123,331,166 JBrowse link
G Shank2 SH3 and multiple ankyrin repeat domains 2 increases expression EXP Nitroglycerin results in increased expression of SHANK2 mRNA CTD PMID:12102619 NCBI chr 1:199,146,210...199,590,962
Ensembl chr 1:199,169,429...199,589,394
JBrowse link
G Slc4a4 solute carrier family 4 member 4 increases expression EXP Nitroglycerin results in increased expression of SLC4A4 mRNA CTD PMID:12102619 NCBI chr14:18,841,289...19,293,297
Ensembl chr14:18,845,159...19,272,883
JBrowse link
G Snn stannin decreases expression EXP Nitroglycerin results in decreased expression of SNN mRNA CTD PMID:12102619 NCBI chr10:4,572,933...4,581,606
Ensembl chr10:4,572,376...4,584,021
JBrowse link
G Snrk SNF related kinase increases expression EXP Nitroglycerin results in increased expression of SNRK mRNA CTD PMID:12102619 NCBI chr 8:121,779,704...121,833,949
Ensembl chr 8:121,793,302...121,832,323
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions EXP Nitroglycerin results in increased expression of and results in increased activity of SOD2 protein CTD PMID:12860443 PMID:14732477 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Stat3 signal transducer and activator of transcription 3 increases expression EXP Nitroglycerin results in increased expression of STAT3 mRNA CTD PMID:12102619 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link
G Syk spleen associated tyrosine kinase increases expression EXP Nitroglycerin results in increased expression of SYK mRNA CTD PMID:12102619 NCBI chr17:12,604,615...12,678,437
Ensembl chr17:12,604,619...12,661,410
JBrowse link
G Syn2 synapsin II increases expression EXP Nitroglycerin results in increased expression of SYN2 mRNA CTD PMID:12102619 NCBI chr 4:148,178,846...148,347,010
Ensembl chr 4:148,186,270...148,344,192
JBrowse link
G Tac1 tachykinin, precursor 1 affects expression EXP Nitroglycerin affects the expression of TAC1 protein CTD PMID:18197882 NCBI chr 4:35,679,183...35,687,180
Ensembl chr 4:35,679,704...35,687,178
JBrowse link
G Tcf4 transcription factor 4 multiple interactions ISO Nitroglycerin inhibits the reaction [CTNNB1 protein binds to TCF4 protein]; Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [Nitroglycerin inhibits the reaction [CTNNB1 protein binds to TCF4 protein]] CTD PMID:17030184 NCBI chr18:62,941,739...63,288,126
Ensembl chr18:62,943,782...63,284,425
JBrowse link
G Tdo2 tryptophan 2,3-dioxygenase decreases expression EXP Nitroglycerin results in decreased expression of TDO2 protein CTD PMID:28659861 NCBI chr 2:167,269,581...167,287,511
Ensembl chr 2:167,269,579...167,287,511
JBrowse link
G Thy1 Thy-1 cell surface antigen decreases expression EXP Nitroglycerin results in decreased expression of THY1 mRNA CTD PMID:12102619 NCBI chr 8:44,389,495...44,394,688
Ensembl chr 8:44,389,513...44,394,659
JBrowse link
G Tmpo thymopoietin increases expression EXP Nitroglycerin results in increased expression of TMPO mRNA CTD PMID:12102619 NCBI chr 7:25,642,752...25,667,756
Ensembl chr 7:25,586,725...25,667,727
JBrowse link
G Tnf tumor necrosis factor decreases expression
multiple interactions
ISO
EXP
Nitroglycerin results in decreased expression of TNF protein
Capsaicin inhibits the reaction [Nitroglycerin results in decreased expression of TNF protein]; Methylene Blue inhibits the reaction [Nitroglycerin results in decreased expression of TNF protein]
CTD PMID:10884648 PMID:11744139 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfrsf8 TNF receptor superfamily member 8 decreases expression EXP Nitroglycerin results in decreased expression of TNFRSF8 mRNA CTD PMID:12102619 NCBI chr 5:157,123,183...157,168,421
Ensembl chr 5:157,123,185...157,168,421
JBrowse link
G Umod uromodulin increases expression EXP Nitroglycerin results in increased expression of UMOD mRNA CTD PMID:12102619 NCBI chr 1:173,816,341...173,829,681
Ensembl chr 1:173,816,339...173,830,302
JBrowse link
G Vasp vasodilator-stimulated phosphoprotein multiple interactions
increases phosphorylation
decreases phosphorylation
ISO
EXP
1H-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one inhibits the reaction [Nitroglycerin results in increased phosphorylation of VASP protein]
Nitroglycerin results in decreased phosphorylation of VASP protein
Benomyl inhibits the reaction [Nitroglycerin results in increased phosphorylation of VASP protein]; Hemin inhibits the reaction [Nitroglycerin results in decreased phosphorylation of VASP protein]
CTD PMID:11331261 PMID:14551241 PMID:15331769 PMID:17541025 PMID:17868048 More... NCBI chr 1:78,910,009...78,925,791
Ensembl chr 1:78,910,011...78,925,061
JBrowse link
G Vtn vitronectin increases expression EXP Nitroglycerin results in increased expression of VTN mRNA CTD PMID:12102619 NCBI chr10:63,394,732...63,397,812
Ensembl chr10:63,394,719...63,397,810
JBrowse link
G Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta decreases expression EXP Nitroglycerin results in decreased expression of YWHAZ mRNA CTD PMID:12102619 NCBI chr 7:67,941,353...67,963,651
Ensembl chr 7:67,940,017...67,963,668
JBrowse link
orphenadrine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin affects expression EXP Orphenadrine affects the expression of A2M mRNA CTD PMID:23665939 NCBI chr 4:154,897,770...154,947,787
Ensembl chr 4:154,897,877...154,947,786
JBrowse link
G Abcb1b ATP-binding cassette, subfamily B (MDR/TAP), member 1B affects expression EXP Orphenadrine affects the expression of ABCB1B mRNA CTD PMID:23665939 NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 multiple interactions EXP [Orphenadrine co-treated with Diethylnitrosamine] results in increased expression of ABCC2 mRNA CTD PMID:23665939 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 affects expression EXP Orphenadrine affects the expression of ABCC3 mRNA CTD PMID:23665939 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595
JBrowse link
G Abcd2 ATP binding cassette subfamily D member 2 affects expression EXP Orphenadrine affects the expression of ABCD2 mRNA CTD PMID:23665939 NCBI chr 7:122,263,034...122,311,642
Ensembl chr 7:122,263,032...122,311,642
JBrowse link
G Ablim3 actin binding LIM protein family, member 3 affects expression EXP Orphenadrine affects the expression of ABLIM3 mRNA CTD PMID:23665939 NCBI chr18:55,256,135...55,376,629
Ensembl chr18:55,257,583...55,376,380
JBrowse link
G Ace2 angiotensin I converting enzyme 2 affects expression EXP Orphenadrine affects the expression of ACE2 mRNA CTD PMID:23665939 NCBI chr  X:30,293,597...30,340,961
Ensembl chr  X:30,293,589...30,340,977
JBrowse link
G Acer3 alkaline ceramidase 3 affects expression EXP Orphenadrine affects the expression of ACER3 mRNA CTD PMID:23665939 NCBI chr 1:152,504,180...152,606,596
Ensembl chr 1:152,504,186...152,606,591
JBrowse link
G Acsl5 acyl-CoA synthetase long-chain family member 5 affects expression EXP Orphenadrine affects the expression of ACSL5 mRNA CTD PMID:23665939 NCBI chr 1:254,289,513...254,336,608
Ensembl chr 1:254,292,521...254,336,607
JBrowse link
G Acsm3 acyl-CoA synthetase medium-chain family member 3 affects expression EXP Orphenadrine affects the expression of ACSM3 mRNA CTD PMID:23665939 NCBI chr 1:174,133,260...174,159,966
Ensembl chr 1:174,133,288...174,160,184
JBrowse link
G Adgrg2 adhesion G protein-coupled receptor G2 affects expression EXP Orphenadrine affects the expression of ADGRG2 mRNA CTD PMID:23665939 NCBI chr  X:34,297,402...34,422,590
Ensembl chr  X:34,297,402...34,422,609
JBrowse link
G Adgrv1 adhesion G protein-coupled receptor V1 affects expression EXP Orphenadrine affects the expression of ADGRV1 mRNA CTD PMID:23665939 NCBI chr 2:11,331,434...11,911,713
Ensembl chr 2:11,331,442...11,911,688
JBrowse link
G Adh4 alcohol dehydrogenase 4 (class II), pi polypeptide affects expression EXP Orphenadrine affects the expression of ADH4 mRNA CTD PMID:23665939 NCBI chr 2:226,948,717...226,966,747 JBrowse link
G Adora1 adenosine A1 receptor affects expression EXP Orphenadrine affects the expression of ADORA1 mRNA CTD PMID:23665939 NCBI chr13:45,658,872...45,695,821
Ensembl chr13:45,658,872...45,695,801
JBrowse link
G Adora2a adenosine A2a receptor affects expression EXP Orphenadrine affects the expression of ADORA2A mRNA CTD PMID:23665939 NCBI chr20:13,315,848...13,333,386
Ensembl chr20:13,315,853...13,333,386
JBrowse link
G Adrb2 adrenoceptor beta 2 affects expression EXP Orphenadrine affects the expression of ADRB2 mRNA CTD PMID:23665939 NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512
JBrowse link
G Ajuba ajuba LIM protein affects expression EXP Orphenadrine affects the expression of JUB mRNA CTD PMID:23665939 NCBI chr15:28,019,775...28,031,537
Ensembl chr15:28,019,778...28,030,021
JBrowse link
G Akr7a3 aldo-keto reductase family 7 member A3 affects expression EXP Orphenadrine affects the expression of AKR7A3 mRNA CTD PMID:23665939 NCBI chr 5:151,590,968...151,601,394
Ensembl chr 5:151,584,479...151,601,394
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 affects expression EXP Orphenadrine affects the expression of ALDH1A1 mRNA CTD PMID:23665939 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
JBrowse link
G Alpl alkaline phosphatase, biomineralization associated affects expression EXP Orphenadrine affects the expression of ALPL mRNA CTD PMID:23665939 NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446
JBrowse link
G Als2cl ALS2 C-terminal like affects expression EXP Orphenadrine affects the expression of ALS2CL mRNA CTD PMID:23665939 NCBI chr 8:110,863,753...110,884,434
Ensembl chr 8:110,864,975...110,884,419
JBrowse link
G Amigo3 adhesion molecule with Ig like domain 3 affects expression EXP Orphenadrine affects the expression of AMIGO3 mRNA CTD PMID:23665939 NCBI chr 8:108,741,899...108,743,425
Ensembl chr 8:108,693,060...108,744,555
JBrowse link
G Amotl2 angiomotin like 2 affects expression EXP Orphenadrine affects the expression of AMOTL2 mRNA CTD PMID:23665939 NCBI chr 8:103,303,368...103,319,161
Ensembl chr 8:103,302,992...103,318,910
JBrowse link
G Angptl4 angiopoietin-like 4 affects expression EXP Orphenadrine affects the expression of ANGPTL4 mRNA CTD PMID:23665939 NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519
JBrowse link
G Angptl6 angiopoietin-like 6 affects expression EXP Orphenadrine affects the expression of ANGPTL6 mRNA CTD PMID:23665939 NCBI chr 8:19,413,617...19,419,925
Ensembl chr 8:19,413,619...19,419,925
JBrowse link
G Ankrd9 ankyrin repeat domain 9 affects expression EXP Orphenadrine affects the expression of ANKRD9 mRNA CTD PMID:23665939 NCBI chr 6:130,001,914...130,008,792
Ensembl chr 6:129,998,486...130,008,923
JBrowse link
G Ano1 anoctamin 1 affects expression EXP Orphenadrine affects the expression of ANO1 mRNA CTD PMID:23665939 NCBI chr 1:199,751,439...199,900,099
Ensembl chr 1:199,751,439...199,900,069
JBrowse link
G Anxa5 annexin A5 affects expression EXP Orphenadrine affects the expression of ANXA5 mRNA CTD PMID:23665939 NCBI chr 2:119,314,007...119,344,703
Ensembl chr 2:119,314,007...119,353,369
JBrowse link
G App amyloid beta precursor protein affects expression EXP Orphenadrine affects the expression of APP mRNA CTD PMID:23665939 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Aqp9 aquaporin 9 affects expression EXP Orphenadrine affects the expression of AQP9 mRNA CTD PMID:23665939 NCBI chr 8:71,797,231...71,837,485
Ensembl chr 8:71,797,234...71,837,395
JBrowse link
G Arhgap10 Rho GTPase activating protein 10 affects expression EXP Orphenadrine affects the expression of ARHGAP10 mRNA CTD PMID:23665939 NCBI chr19:30,448,572...30,710,315
Ensembl chr19:30,448,637...30,710,313
JBrowse link
G Arhgap22 Rho GTPase activating protein 22 affects expression EXP Orphenadrine affects the expression of ARHGAP22 mRNA CTD PMID:23665939 NCBI chr16:8,473,806...8,631,552
Ensembl chr16:8,476,306...8,631,548
JBrowse link
G Arhgef10 Rho guanine nucleotide exchange factor 10 affects expression EXP Orphenadrine affects the expression of ARHGEF10 mRNA CTD PMID:23665939 NCBI chr16:74,647,147...74,738,784
Ensembl chr16:74,647,153...74,738,173
JBrowse link
G Arhgef15 Rho guanine nucleotide exchange factor 15 affects expression EXP Orphenadrine affects the expression of ARHGEF15 mRNA CTD PMID:23665939 NCBI chr10:53,650,521...53,662,914
Ensembl chr10:53,650,553...53,663,913
JBrowse link
G Armcx1 armadillo repeat containing, X-linked 1 affects expression EXP Orphenadrine affects the expression of ARMCX1 mRNA CTD PMID:23665939 NCBI chr  X:97,898,969...97,902,874
Ensembl chr  X:97,898,883...97,903,299
JBrowse link
G Arrdc2 arrestin domain containing 2 affects expression EXP Orphenadrine affects the expression of ARRDC2 mRNA CTD PMID:23665939 NCBI chr16:18,601,897...18,606,029
Ensembl chr16:18,601,897...18,606,029
JBrowse link
G Atf3 activating transcription factor 3 affects expression EXP Orphenadrine affects the expression of ATF3 mRNA CTD PMID:23665939 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
JBrowse link
G Atp2b2 ATPase plasma membrane Ca2+ transporting 2 affects expression EXP Orphenadrine affects the expression of ATP2B2 mRNA CTD PMID:23665939 NCBI chr 4:146,896,332...147,140,665
Ensembl chr 4:146,896,332...147,140,665
JBrowse link
G Atrnl1 attractin like 1 affects expression EXP Orphenadrine affects the expression of ATRNL1 mRNA CTD PMID:23665939 NCBI chr 1:256,670,976...257,219,291
Ensembl chr 1:256,670,627...257,213,197
JBrowse link
G Azin2 antizyme inhibitor 2 affects expression EXP Orphenadrine affects the expression of AZIN2 mRNA CTD PMID:23665939 NCBI chr 5:141,281,310...141,310,415
Ensembl chr 5:141,281,249...141,310,397
JBrowse link
G B3gnt9 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9 affects expression EXP Orphenadrine affects the expression of B3GNT9 mRNA CTD PMID:23665939 NCBI chr19:33,129,740...33,134,048
Ensembl chr19:33,128,142...33,132,344
JBrowse link
G B4galt6 beta-1,4-galactosyltransferase 6 affects expression EXP Orphenadrine affects the expression of B4GALT6 mRNA CTD PMID:23665939 NCBI chr18:11,958,382...12,015,247
Ensembl chr18:11,958,390...12,015,247
JBrowse link
G Bambi BMP and activin membrane-bound inhibitor affects expression EXP Orphenadrine affects the expression of BAMBI mRNA CTD PMID:23665939 NCBI chr17:54,121,251...54,125,816
Ensembl chr17:54,121,255...54,126,060
JBrowse link
G Bbc3 Bcl-2 binding component 3 affects expression EXP Orphenadrine affects the expression of BBC3 mRNA CTD PMID:23665939 NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509
JBrowse link
G Bcl6 BCL6, transcription repressor affects expression EXP Orphenadrine affects the expression of BCL6 mRNA CTD PMID:23665939 NCBI chr11:76,854,090...76,877,389
Ensembl chr11:76,854,090...76,877,389
JBrowse link
G Bco2 beta-carotene oxygenase 2 affects expression EXP Orphenadrine affects the expression of BCO2 mRNA CTD PMID:23665939 NCBI chr 8:50,882,174...50,907,676
Ensembl chr 8:50,882,181...50,915,467
JBrowse link
G Bhlha15 basic helix-loop-helix family, member a15 affects expression EXP Orphenadrine affects the expression of BHLHA15 mRNA CTD PMID:23665939 NCBI chr12:10,420,465...10,424,641
Ensembl chr12:10,420,467...10,424,713
JBrowse link
G Bicc1 BicC family RNA binding protein 1 affects expression EXP Orphenadrine affects the expression of BICC1 mRNA CTD PMID:23665939 NCBI chr20:17,449,644...17,686,775
Ensembl chr20:17,449,560...17,686,776
JBrowse link
G Bmp4 bone morphogenetic protein 4 affects expression EXP Orphenadrine affects the expression of BMP4 mRNA CTD PMID:23665939 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306
JBrowse link
G Btbd7 BTB domain containing 7 affects expression EXP Orphenadrine affects the expression of BTBD7 mRNA CTD PMID:23665939 NCBI chr 6:121,920,365...122,010,114
Ensembl chr 6:121,923,023...121,972,405
JBrowse link
G C1qtnf2 C1q and TNF related 2 affects expression EXP Orphenadrine affects the expression of C1QTNF2 mRNA CTD PMID:23665939 NCBI chr10:27,941,948...27,958,926
Ensembl chr10:27,941,948...27,959,185
JBrowse link
G Ca3 carbonic anhydrase 3 affects expression EXP Orphenadrine affects the expression of CA3 mRNA CTD PMID:23665939 NCBI chr 2:86,770,418...86,780,011
Ensembl chr 2:86,770,420...86,784,280
JBrowse link
G Calcrl calcitonin receptor like receptor affects expression EXP Orphenadrine affects the expression of CALCRL mRNA CTD PMID:23665939 NCBI chr 3:69,428,348...69,525,910
Ensembl chr 3:69,430,120...69,525,910
JBrowse link
G Car1 carbonic anhydrase 1 affects expression EXP Orphenadrine affects the expression of CA1 mRNA CTD PMID:23665939 NCBI chr 2:86,829,436...86,872,209
Ensembl chr 2:86,861,897...86,872,208
JBrowse link
G Car2 carbonic anhydrase 2 affects expression EXP Orphenadrine affects the expression of CA2 mRNA CTD PMID:23665939 NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818
JBrowse link
G Card19 caspase recruitment domain family, member 19 affects expression EXP Orphenadrine affects the expression of CARD19 mRNA CTD PMID:23665939 NCBI chr17:15,432,572...15,445,318
Ensembl chr17:15,432,612...15,445,318
JBrowse link
G Casp2 caspase 2 affects expression EXP Orphenadrine affects the expression of CASP2 mRNA CTD PMID:23665939 NCBI chr 4:71,149,632...71,167,388
Ensembl chr 4:71,149,669...71,167,379
JBrowse link
G Cblc Cbl proto-oncogene C affects expression EXP Orphenadrine affects the expression of CBLC mRNA CTD PMID:23665939 NCBI chr 1:79,439,975...79,456,755
Ensembl chr 1:79,439,977...79,456,755
JBrowse link
G Cbx4 chromobox 4 affects expression EXP Orphenadrine affects the expression of CBX4 mRNA CTD PMID:23665939 NCBI chr10:104,337,140...104,343,210 JBrowse link
G Ccdc68 coiled-coil domain containing 68 affects expression EXP Orphenadrine affects the expression of CCDC68 mRNA CTD PMID:23665939 NCBI chr18:63,541,828...63,584,122
Ensembl chr18:63,541,896...63,584,119
JBrowse link
G Ccn1 cellular communication network factor 1 affects expression EXP Orphenadrine affects the expression of CCN1 mRNA CTD PMID:23665939 NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484
JBrowse link
G Ccnd1 cyclin D1 multiple interactions EXP Orphenadrine promotes the reaction [Diethylnitrosamine results in increased expression of CCND1 mRNA] CTD PMID:23665939 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccnd2 cyclin D2 affects expression EXP Orphenadrine affects the expression of CCND2 mRNA CTD PMID:23665939 NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495
JBrowse link
G Cd24 CD24 molecule affects expression EXP Orphenadrine affects the expression of CD24 mRNA CTD PMID:23665939 NCBI chr20:47,074,353...47,079,662
Ensembl chr20:47,073,512...47,079,662
JBrowse link
G Cd276 Cd276 molecule affects expression EXP Orphenadrine affects the expression of CD276 mRNA CTD PMID:23665939 NCBI chr 8:58,937,751...58,968,082
Ensembl chr 8:58,937,751...58,968,380
JBrowse link
G Cd36 CD36 molecule affects expression EXP Orphenadrine affects the expression of CD36 mRNA CTD PMID:23665939 NCBI chr 4:17,317,343...17,410,084 JBrowse link
G Cdc42ep1 CDC42 effector protein 1 affects expression EXP Orphenadrine affects the expression of CDC42EP1 mRNA CTD PMID:23665939 NCBI chr 7:110,395,287...110,403,203
Ensembl chr 7:110,395,332...110,403,200
JBrowse link
G Cdh3 cadherin 3 affects expression EXP Orphenadrine affects the expression of CDH3 mRNA CTD PMID:23665939 NCBI chr19:34,393,596...34,444,084
Ensembl chr19:34,393,727...34,444,084
JBrowse link
G Cdr2 cerebellar degeneration-related protein 2 affects expression EXP Orphenadrine affects the expression of CDR2 mRNA CTD PMID:23665939 NCBI chr 1:175,502,837...175,527,746
Ensembl chr 1:175,502,838...175,537,472
JBrowse link
G Ces2h carboxylesterase 2H affects expression EXP Orphenadrine affects the expression of CES2 mRNA CTD PMID:23665939 NCBI chr19:32,974,242...32,988,842
Ensembl chr19:32,974,242...32,988,830
JBrowse link
G Cgref1 cell growth regulator with EF hand domain 1 affects expression EXP Orphenadrine affects the expression of CGREF1 mRNA CTD PMID:23665939 NCBI chr 6:25,431,846...25,443,853
Ensembl chr 6:25,431,799...25,443,852
JBrowse link
G Chmp4c charged multivesicular body protein 4C affects expression EXP Orphenadrine affects the expression of CHMP4C mRNA CTD PMID:23665939 NCBI chr 2:91,391,729...91,428,652
Ensembl chr 2:91,388,530...91,428,668
JBrowse link
G Cidea cell death-inducing DFFA-like effector a affects expression EXP Orphenadrine affects the expression of CIDEA mRNA CTD PMID:23665939 NCBI chr18:60,894,917...60,920,485
Ensembl chr18:60,894,874...60,920,481
JBrowse link
G Cish cytokine inducible SH2-containing protein affects expression EXP Orphenadrine affects the expression of CISH mRNA CTD PMID:23665939 NCBI chr 8:107,972,306...107,977,254
Ensembl chr 8:107,972,306...107,977,250
JBrowse link
G Clcf1 cardiotrophin-like cytokine factor 1 affects expression EXP Orphenadrine affects the expression of CLCF1 mRNA CTD PMID:23665939 NCBI chr 1:201,507,763...201,517,607
Ensembl chr 1:201,507,859...201,517,605
JBrowse link
G Cldn23 claudin 23 affects expression EXP Orphenadrine affects the expression of CLDN23 mRNA CTD PMID:23665939 NCBI chr16:56,413,677...56,415,401
Ensembl chr16:56,413,381...56,415,523
JBrowse link
G Cndp1 carnosine dipeptidase 1 affects expression EXP Orphenadrine affects the expression of CNDP1 mRNA CTD PMID:23665939 NCBI chr18:77,984,886...78,030,837
Ensembl chr18:77,984,907...78,007,765
JBrowse link
G Col4a3 collagen type IV alpha 3 chain affects expression EXP Orphenadrine affects the expression of COL4A3 mRNA CTD PMID:23665939 NCBI chr 9:83,875,958...84,004,955
Ensembl chr 9:83,875,561...84,001,895
JBrowse link
G Cpt1b carnitine palmitoyltransferase 1B affects expression EXP Orphenadrine affects the expression of CPT1B mRNA CTD PMID:23665939 NCBI chr 7:120,491,354...120,500,833
Ensembl chr 7:120,491,354...120,500,404
JBrowse link
G Crat carnitine O-acetyltransferase affects expression EXP Orphenadrine affects the expression of CRAT mRNA CTD PMID:23665939 NCBI chr 3:13,675,684...13,689,282
Ensembl chr 3:13,675,684...13,689,255
JBrowse link
G Crlf2 cytokine receptor-like factor 2 affects expression EXP Orphenadrine affects the expression of CRLF2 mRNA CTD PMID:23665939 NCBI chr14:103,943...108,643
Ensembl chr14:103,939...108,642
JBrowse link
G Cryab crystallin, alpha B affects expression EXP Orphenadrine affects the expression of CRYAB mRNA CTD PMID:23665939 NCBI chr 8:51,093,441...51,099,161
Ensembl chr 8:51,093,441...51,099,157
JBrowse link
G Cryl1 crystallin, lambda 1 affects expression EXP Orphenadrine affects the expression of CRYL1 mRNA CTD PMID:23665939 NCBI chr15:31,427,011...31,545,997
Ensembl chr15:31,427,054...31,545,997
JBrowse link
G Csmd1 CUB and Sushi multiple domains 1 affects expression EXP Orphenadrine affects the expression of CSMD1 mRNA CTD PMID:23665939 NCBI chr16:72,218,189...73,818,380
Ensembl chr16:72,218,503...73,817,614
JBrowse link
G Csrnp1 cysteine and serine rich nuclear protein 1 affects expression EXP Orphenadrine affects the expression of CSRNP1 mRNA CTD PMID:23665939 NCBI chr 8:119,704,712...119,717,767
Ensembl chr 8:119,704,713...119,718,183
JBrowse link
G Cst9l cystatin 9-like affects expression EXP Orphenadrine affects the expression of CST9L mRNA CTD PMID:23665939 NCBI chr 3:136,288,093...136,290,906
Ensembl chr 3:136,288,093...136,290,906
JBrowse link
G Ctps1 CTP synthase 1 affects expression EXP Orphenadrine affects the expression of CTPS mRNA CTD PMID:23665939 NCBI chr 5:134,125,022...134,154,155
Ensembl chr 5:134,125,025...134,154,180
JBrowse link
G Ctrb1 chymotrypsinogen B1 affects expression EXP Orphenadrine affects the expression of CTRB mRNA CTD PMID:23665939 NCBI chr19:39,652,931...39,657,666
Ensembl chr19:39,652,933...39,657,688
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
affects expression
EXP [Orphenadrine co-treated with Diethylnitrosamine] results in increased expression of CYP1A1 mRNA
Orphenadrine affects the expression of CYP1A1 mRNA
CTD PMID:23665939 PMID:23665940 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions
decreases activity
ISO
EXP
Orphenadrine inhibits the reaction [CYP1A2 protein results in decreased ethylation of 7-ethoxy-4-trifluoromethylcoumarin]; Orphenadrine inhibits the reaction [CYP1A2 protein results in increased chemical synthesis of 7-hydroxy-4-trifluoromethylcoumarin]
Orphenadrine inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]
Orphenadrine results in decreased activity of CYP1A2 protein
CTD PMID:9241656 PMID:18493746 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp2b15 cytochrome P450, family 2, subfamily b, polypeptide 15 affects expression EXP Orphenadrine affects the expression of CYP2B15 mRNA CTD PMID:23665939 NCBI chr 1:82,094,188...82,106,492
Ensembl chr 1:82,094,180...82,106,492
JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 affects expression
multiple interactions
EXP Orphenadrine affects the expression of CYP2B2 mRNA
[Orphenadrine co-treated with Phenobarbital] affects the expression of CYP2B2 mRNA
CTD PMID:23665939 PMID:23665940 NCBI chr 1:81,594,534...81,608,567
Ensembl chr 1:81,594,555...81,608,566
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 multiple interactions
decreases activity
ISO Orphenadrine inhibits the reaction [CYP2B6 protein results in decreased ethylation of 7-ethoxy-4-trifluoromethylcoumarin]; Orphenadrine inhibits the reaction [CYP2B6 protein results in increased chemical synthesis of 7-hydroxy-4-trifluoromethylcoumarin]
Orphenadrine results in decreased activity of CYP2B6 protein
CTD PMID:9241656 PMID:12464242 PMID:15306208 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
JBrowse link
G Cyp2c12 cytochrome P450, family 2, subfamily c, polypeptide 12 affects expression EXP Orphenadrine affects the expression of CYP2C12 mRNA CTD PMID:23665939 NCBI chr 1:238,699,859...238,757,011
Ensembl chr 1:238,699,854...238,757,019
JBrowse link
G Cyp2c24 cytochrome P450, family 2, subfamily c, polypeptide 24 affects expression EXP Orphenadrine affects the expression of CYP2C24 mRNA CTD PMID:23665939 NCBI chr 1:236,873,967...236,936,238
Ensembl chr 1:236,873,967...236,936,238
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions
decreases activity
ISO Orphenadrine inhibits the reaction [CYP2E1 protein results in decreased ethylation of 7-ethoxy-4-trifluoromethylcoumarin]; Orphenadrine inhibits the reaction [CYP2E1 protein results in increased chemical synthesis of 7-hydroxy-4-trifluoromethylcoumarin]
Orphenadrine results in decreased activity of CYP2E1 protein
CTD PMID:9241656 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Cyp3a62 cytochrome P450, family 3, subfamily a, polypeptide 62 affects expression EXP Orphenadrine affects the expression of CYP3A62 mRNA CTD PMID:23665939 NCBI chr12:16,397,998...16,433,833
Ensembl chr12:16,397,998...16,433,833
JBrowse link
G Cyp4a1 cytochrome P450, family 4, subfamily a, polypeptide 1 affects expression EXP Orphenadrine affects the expression of CYP4A1 mRNA CTD PMID:23665939 NCBI chr 5:129,123,323...129,137,464
Ensembl chr 5:129,123,336...129,137,464
JBrowse link
G Cyp4a8 cytochrome P450, family 4, subfamily a, polypeptide 8 affects expression EXP Orphenadrine affects the expression of CYP4A8 mRNA CTD PMID:23665939 NCBI chr 5:128,702,130...128,733,476
Ensembl chr 5:128,702,131...128,733,476
JBrowse link
G Cyp4b1 cytochrome P450, family 4, subfamily b, polypeptide 1 affects expression EXP Orphenadrine affects the expression of CYP4B1 mRNA CTD PMID:23665939 NCBI chr 5:129,139,019...129,176,860
Ensembl chr 5:129,139,038...129,156,348
JBrowse link
G Cyp4f5 cytochrome P450, family 4, subfamily f, polypeptide 5 affects expression EXP Orphenadrine affects the expression of CYP4F5 mRNA CTD PMID:23665939 NCBI chr 7:11,544,040...11,558,982
Ensembl chr 7:11,544,082...11,558,978
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 affects expression EXP Orphenadrine affects the expression of CYP7A1 mRNA CTD PMID:23665939 NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
JBrowse link
G Cyp8b1 cytochrome P450 family 8 subfamily B member 1 affects expression EXP Orphenadrine affects the expression of CYP8B1 mRNA CTD PMID:23665939 NCBI chr 8:121,578,123...121,580,093
Ensembl chr 8:121,557,062...121,580,166
JBrowse link
G Cystm1 cysteine-rich transmembrane module containing 1 affects expression EXP Orphenadrine affects the expression of CYSTM1 mRNA CTD PMID:23665939 NCBI chr18:27,945,862...28,013,509
Ensembl chr18:27,951,653...28,013,510
JBrowse link
G Cyyr1 cysteine and tyrosine rich 1 affects expression EXP Orphenadrine affects the expression of CYYR1 mRNA CTD PMID:23665939 NCBI chr11:24,557,620...24,664,007
Ensembl chr11:24,515,316...24,663,961
JBrowse link
G Dact2 dishevelled-binding antagonist of beta-catenin 2 affects expression EXP Orphenadrine affects the expression of DACT2 mRNA CTD PMID:23665939 NCBI chr 1:55,181,023...55,191,026
Ensembl chr 1:55,181,024...55,191,096
JBrowse link
G Defb36 defensin beta 36 affects expression EXP Orphenadrine affects the expression of DEFB36 mRNA CTD PMID:23665939 NCBI chr 3:141,078,001...141,086,832
Ensembl chr 3:141,086,058...141,086,728
JBrowse link
G Dip2a disco-interacting protein 2 homolog A affects expression EXP Orphenadrine affects the expression of DIP2A mRNA CTD PMID:23665939 NCBI chr20:12,284,566...12,371,068
Ensembl chr20:12,284,654...12,370,217
JBrowse link
G Dll1 delta like canonical Notch ligand 1 affects expression EXP Orphenadrine affects the expression of DLL1 mRNA CTD PMID:23665939 NCBI chr 1:56,312,062...56,320,177
Ensembl chr 1:56,312,066...56,320,179
JBrowse link
G Dnhd1 dynein heavy chain domain 1 affects expression EXP Orphenadrine affects the expression of DNHD1 mRNA CTD PMID:23665939 NCBI chr 1:159,990,785...160,077,990
Ensembl chr 1:159,990,438...160,074,858
JBrowse link
G Dpp6 dipeptidyl peptidase like 6 affects expression EXP Orphenadrine affects the expression of DPP6 mRNA CTD PMID:23665939 NCBI chr 4:7,589,386...8,508,666
Ensembl chr 4:7,591,009...8,508,532
JBrowse link
G Dram1 DNA-damage regulated autophagy modulator 1 affects expression EXP Orphenadrine affects the expression of DRAM1 mRNA CTD PMID:23665939 NCBI chr 7:22,742,794...22,776,888
Ensembl chr 7:22,742,849...22,776,765
JBrowse link
G Dusp1 dual specificity phosphatase 1 affects expression EXP Orphenadrine affects the expression of DUSP1 mRNA CTD PMID:23665939 NCBI chr10:16,680,489...16,683,276 JBrowse link
G Dusp10 dual specificity phosphatase 10 affects expression EXP Orphenadrine affects the expression of DUSP10 mRNA CTD PMID:23665939 NCBI chr13:95,613,716...95,651,716
Ensembl chr13:95,614,292...95,651,716
JBrowse link
G Dusp13 dual specificity phosphatase 13 affects expression EXP Orphenadrine affects the expression of DUSP13 mRNA CTD PMID:23665939 NCBI chr15:2,559,720...2,575,105
Ensembl chr15:2,533,547...2,575,539
JBrowse link
G Dusp16 dual specificity phosphatase 16 affects expression EXP Orphenadrine affects the expression of DUSP16 mRNA CTD PMID:23665939 NCBI chr 4:167,546,780...167,629,949
Ensembl chr 4:167,548,155...167,629,980
JBrowse link
G Dusp8 dual specificity phosphatase 8 affects expression EXP Orphenadrine affects the expression of DUSP8 mRNA CTD PMID:23665939 NCBI chr 1:197,167,392...197,184,285
Ensembl chr 1:197,169,422...197,182,921
JBrowse link
G Efemp1 EGF containing fibulin extracellular matrix protein 1 affects expression EXP Orphenadrine affects the expression of EFEMP1 mRNA CTD PMID:23665939 NCBI chr14:102,610,813...102,690,027
Ensembl chr14:102,610,908...102,690,018
JBrowse link
G Egln3 egl-9 family hypoxia-inducible factor 3 affects expression EXP Orphenadrine affects the expression of EGLN3 mRNA CTD PMID:23665939 NCBI chr 6:71,650,297...71,675,766
Ensembl chr 6:71,650,297...71,675,766
JBrowse link
G Egr1 early growth response 1 affects expression EXP Orphenadrine affects the expression of EGR1 mRNA CTD PMID:23665939 NCBI chr18:26,463,333...26,465,531
Ensembl chr18:26,462,981...26,466,766
JBrowse link
G Emilin1 elastin microfibril interfacer 1 affects expression EXP Orphenadrine affects the expression of EMILIN1 mRNA CTD PMID:23665939 NCBI chr 6:25,455,974...25,463,736
Ensembl chr 6:25,445,298...25,463,698
JBrowse link
G Epha2 Eph receptor A2 affects expression EXP Orphenadrine affects the expression of EPHA2 mRNA CTD PMID:23665939 NCBI chr 5:153,605,644...153,634,115
Ensembl chr 5:153,605,644...153,634,117
JBrowse link
G Ephb4 EPH receptor B4 affects expression EXP Orphenadrine affects the expression of EPHB4 mRNA CTD PMID:23665939 NCBI chr12:19,326,411...19,351,667
Ensembl chr12:19,326,427...19,351,314
JBrowse link
G Eri2 ERI1 exoribonuclease family member 2 affects expression EXP Orphenadrine affects the expression of ERI2 mRNA CTD PMID:23665939 NCBI chr 1:174,140,831...174,168,757
Ensembl chr 1:174,141,993...174,168,665
JBrowse link
G F8 coagulation factor VIII affects expression EXP Orphenadrine affects the expression of F8 mRNA CTD PMID:23665939 NCBI chr18:140,848...172,330
Ensembl chr18:140,955...171,857
JBrowse link
G Fam102a family with sequence similarity 102, member A affects expression EXP Orphenadrine affects the expression of FAM102A mRNA CTD PMID:23665939 NCBI chr 3:15,823,147...15,854,651
Ensembl chr 3:15,823,144...15,854,643
JBrowse link
G Fam102b family with sequence similarity 102, member B affects expression EXP Orphenadrine affects the expression of FAM102B mRNA CTD PMID:23665939 NCBI chr 2:196,608,499...196,663,371
Ensembl chr 2:196,608,499...196,663,371
JBrowse link
G Fam126a family with sequence similarity 126, member A affects expression EXP Orphenadrine affects the expression of FAM126A mRNA CTD PMID:23665939 NCBI chr 4:11,132,224...11,239,120
Ensembl chr 4:11,132,385...11,239,113
JBrowse link
G Fam89a family with sequence similarity 89, member A affects expression EXP Orphenadrine affects the expression of FAM89A mRNA CTD PMID:23665939 NCBI chr19:52,710,003...52,722,591
Ensembl chr19:52,710,019...52,722,631
JBrowse link
G Fbxo27 F-box protein 27 affects expression EXP Orphenadrine affects the expression of FBXO27 mRNA CTD PMID:23665939 NCBI chr 1:83,965,426...83,987,781 JBrowse link
G Fer1l5 fer-1-like family member 5 affects expression EXP Orphenadrine affects the expression of FER1L5 mRNA CTD PMID:23665939 NCBI chr 9:38,605,835...38,661,869
Ensembl chr 9:38,607,843...38,660,425
JBrowse link
G Fgd5 FYVE, RhoGEF and PH domain containing 5 affects expression EXP Orphenadrine affects the expression of FGD5 mRNA CTD PMID:23665939 NCBI chr 4:124,497,061...124,594,564
Ensembl chr 4:124,497,068...124,594,563
JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 affects expression EXP Orphenadrine affects the expression of FLT1 mRNA CTD PMID:23665939 NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626
JBrowse link
G Flt4 Fms related receptor tyrosine kinase 4 affects expression EXP Orphenadrine affects the expression of FLT4 mRNA CTD PMID:23665939 NCBI chr10:33,913,725...33,954,770
Ensembl chr10:33,913,608...33,954,770
JBrowse link
G Fmo1 flavin containing dimethylaniline monoxygenase 1 affects expression EXP Orphenadrine affects the expression of FMO1 mRNA CTD PMID:23665939 NCBI chr13:75,182,184...75,214,439
Ensembl chr13:75,182,176...75,214,647
JBrowse link
G Fndc5 fibronectin type III domain containing 5 affects expression EXP Orphenadrine affects the expression of FNDC5 mRNA CTD PMID:23665939 NCBI chr 5:141,481,593...141,491,257
Ensembl chr 5:141,481,590...141,490,731
JBrowse link
G Fst follistatin affects expression EXP Orphenadrine affects the expression of FST mRNA CTD PMID:23665939 NCBI chr 2:46,123,260...46,130,584
Ensembl chr 2:46,123,439...46,130,571
JBrowse link
G Gadd45g growth arrest and DNA-damage-inducible, gamma affects expression EXP Orphenadrine affects the expression of GADD45G mRNA CTD PMID:23665939 NCBI chr17:13,376,842...13,378,587
Ensembl chr17:13,376,839...13,378,610
JBrowse link
G Gdf11 growth differentiation factor 11 affects expression EXP Orphenadrine affects the expression of GDF11 mRNA CTD PMID:23665939 NCBI chr 7:1,311,732...1,325,211
Ensembl chr 7:1,311,732...1,320,725
JBrowse link
G Ggt1 gamma-glutamyltransferase 1 affects expression EXP Orphenadrine affects the expression of GGT1 mRNA CTD PMID:23665939 NCBI chr20:13,074,695...13,104,095
Ensembl chr20:13,074,700...13,108,442
JBrowse link
G Gimd1 GIMAP family P-loop NTPase domain containing 1 affects expression EXP Orphenadrine affects the expression of GIMD1 mRNA CTD PMID:23665939 NCBI chr 2:221,103,878...221,138,559
Ensembl chr 2:221,103,878...221,138,553
JBrowse link
G Gipc2 GIPC PDZ domain containing family, member 2 affects expression EXP Orphenadrine affects the expression of GIPC2 mRNA CTD PMID:23665939 NCBI chr 2:241,030,764...241,110,236
Ensembl chr 2:241,030,770...241,110,236
JBrowse link
G Gmip Gem-interacting protein affects expression EXP Orphenadrine affects the expression of GMIP mRNA CTD PMID:23665939 NCBI chr16:19,600,723...19,614,459
Ensembl chr16:19,600,723...19,614,027
JBrowse link
G Gna14 G protein subunit alpha 14 affects expression EXP Orphenadrine affects the expression of GNA14 mRNA CTD PMID:23665939 NCBI chr 1:213,714,993...213,900,083
Ensembl chr 1:213,716,020...213,897,423
JBrowse link
G Gnai1 G protein subunit alpha i1 affects expression EXP Orphenadrine affects the expression of GNAI1 mRNA CTD PMID:23665939 NCBI chr 4:16,813,941...16,898,111
Ensembl chr 4:16,814,001...16,896,417
JBrowse link
G Gpat3 glycerol-3-phosphate acyltransferase 3 affects expression EXP Orphenadrine affects the expression of GPAT3 mRNA CTD PMID:23665939 NCBI chr14:8,715,367...8,768,051
Ensembl chr14:8,714,373...8,766,490
JBrowse link
G Gpr17 G protein-coupled receptor 17 affects expression EXP Orphenadrine affects the expression of GPR17 mRNA CTD PMID:23665939 NCBI chr18:23,576,212...23,583,177
Ensembl chr18:23,577,242...23,582,966
JBrowse link
G Gpx2 glutathione peroxidase 2 affects expression
multiple interactions
EXP Orphenadrine affects the expression of GPX2 mRNA
[Orphenadrine co-treated with Diethylnitrosamine] results in increased expression of GPX2 mRNA; [Phenobarbital co-treated with Orphenadrine] affects the expression of GPX2 mRNA
CTD PMID:23665939 PMID:23665940 NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877
JBrowse link
G Gria3 glutamate ionotropic receptor AMPA type subunit 3 affects expression EXP Orphenadrine affects the expression of GRIA3 mRNA CTD PMID:23665939 NCBI chr  X:120,238,515...120,504,106
Ensembl chr  X:120,238,534...120,504,096
JBrowse link
G Grik5 glutamate ionotropic receptor kainate type subunit 5 affects expression EXP Orphenadrine affects the expression of GRIK5 mRNA CTD PMID:23665939 NCBI chr 1:80,605,878...80,667,896
Ensembl chr 1:80,605,892...80,667,125
JBrowse link
G Gse1 Gse1 coiled-coil protein affects expression EXP Orphenadrine affects the expression of GSE1 mRNA CTD PMID:23665939 NCBI chr19:48,274,164...48,629,456
Ensembl chr19:48,274,127...48,629,458
JBrowse link
G Gstm4 glutathione S-transferase mu 4 affects expression EXP Orphenadrine affects the expression of GSTM4 mRNA CTD PMID:23665939 NCBI chr 2:195,667,940...195,685,315
Ensembl chr 2:195,680,004...195,685,323
JBrowse link
G Gstm5 glutathione S-transferase, mu 5 multiple interactions
affects expression
EXP [Orphenadrine co-treated with Diethylnitrosamine] results in increased expression of GSTM3 mRNA; [Phenobarbital co-treated with Orphenadrine] affects the expression of GSTM3 mRNA
Orphenadrine affects the expression of GSTM3 mRNA
CTD PMID:23665939 PMID:23665940 NCBI chr 2:195,531,627...195,534,562
Ensembl chr 2:195,531,495...195,534,553
JBrowse link
G Gstp1 glutathione S-transferase pi 1 affects expression EXP Orphenadrine affects the expression of GSTP1 mRNA CTD PMID:23665939 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link
G Hal histidine ammonia lyase affects expression EXP Orphenadrine affects the expression of HAL mRNA CTD PMID:23665939 NCBI chr 7:28,007,449...28,037,701
Ensembl chr 7:28,006,972...28,037,701
JBrowse link
G Hebp2 heme binding protein 2 affects expression EXP Orphenadrine affects the expression of HEBP2 mRNA CTD PMID:23665939 NCBI chr 1:13,194,982...13,201,777
Ensembl chr 1:13,194,982...13,201,777
JBrowse link
G Hes1 hes family bHLH transcription factor 1 affects expression EXP Orphenadrine affects the expression of HES1 mRNA CTD PMID:23665939 NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192
JBrowse link
G Hgf hepatocyte growth factor affects expression EXP Orphenadrine affects the expression of HGF mRNA CTD PMID:23665939 NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409
JBrowse link
G Hid1 HID1 domain containing affects expression EXP Orphenadrine affects the expression of HID1 mRNA CTD PMID:23665939 NCBI chr10:100,589,555...100,610,050
Ensembl chr10:100,589,555...100,610,041
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A affects expression EXP Orphenadrine affects the expression of HSPA1A mRNA CTD PMID:23665939
G Hspa1b heat shock protein family A (Hsp70) member 1B affects expression EXP Orphenadrine affects the expression of HSPA1B mRNA CTD PMID:23665939 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein affects expression EXP Orphenadrine affects the expression of ID1 mRNA CTD PMID:23665939 NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419
JBrowse link
G Id3 inhibitor of DNA binding 3, HLH protein affects expression EXP Orphenadrine affects the expression of ID3 mRNA CTD PMID:23665939 NCBI chr 5:148,372,784...148,374,353
Ensembl chr 5:148,372,762...148,374,349
JBrowse link
G Ido2 indoleamine 2,3-dioxygenase 2 affects expression EXP Orphenadrine affects the expression of IDO2 mRNA CTD PMID:23665939 NCBI chr16:67,459,158...67,498,052
Ensembl chr16:67,459,190...67,496,324
JBrowse link
G Ier5 immediate early response 5 affects expression EXP Orphenadrine affects the expression of IER5 mRNA CTD PMID:23665939 NCBI chr13:67,270,134...67,272,226
Ensembl chr13:67,270,135...67,272,227
JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 affects expression EXP Orphenadrine affects the expression of IGFBP1 mRNA CTD PMID:23665939 NCBI chr14:82,047,415...82,052,482
Ensembl chr14:82,047,415...82,052,482
JBrowse link
G Ihh Indian hedgehog signaling molecule affects expression EXP Orphenadrine affects the expression of IHH mRNA CTD PMID:23665939 NCBI chr 9:76,504,315...76,510,532
Ensembl chr 9:76,504,315...76,510,532
JBrowse link
G Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma affects expression EXP Orphenadrine affects the expression of IKBKG mRNA CTD PMID:23665939 NCBI chr  X:152,216,485...152,241,476
Ensembl chr  X:152,216,596...152,239,499
JBrowse link
G Il17rb interleukin 17 receptor B affects expression EXP Orphenadrine affects the expression of IL17RB mRNA CTD PMID:23665939 NCBI chr16:5,180,431...5,194,125
Ensembl chr16:5,180,432...5,194,125
JBrowse link
G Il33 interleukin 33 affects expression EXP Orphenadrine affects the expression of IL33 mRNA CTD PMID:23665939 NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373
JBrowse link
G Inf2 inverted formin 2 affects expression EXP Orphenadrine affects the expression of INF2 mRNA CTD PMID:23665939 NCBI chr 6:131,649,162...131,675,944
Ensembl chr 6:131,649,211...131,675,941
JBrowse link
G Ip6k2 inositol hexakisphosphate kinase 2 affects expression EXP Orphenadrine affects the expression of IP6K2 mRNA CTD PMID:23665939 NCBI chr 8:109,483,843...109,510,172
Ensembl chr 8:109,484,310...109,510,166
JBrowse link
G Irf7 interferon regulatory factor 7 affects expression EXP Orphenadrine affects the expression of IRF7 mRNA CTD PMID:23665939 NCBI chr 1:196,367,380...196,370,943
Ensembl chr 1:196,367,361...196,370,832
JBrowse link
G Irx1 iroquois homeobox 1 affects expression EXP Orphenadrine affects the expression of IRX1 mRNA CTD PMID:23665939 NCBI chr 1:31,294,615...31,300,444
Ensembl chr 1:31,294,615...31,300,444
JBrowse link
G Isg15 ISG15 ubiquitin-like modifier affects expression EXP Orphenadrine affects the expression of ISG15 mRNA CTD PMID:23665939 NCBI chr 5:166,784,148...166,785,435
Ensembl chr 5:166,784,148...166,785,435
JBrowse link
G Itgb3 integrin subunit beta 3 affects expression EXP Orphenadrine affects the expression of ITGB3 mRNA CTD PMID:23665939 NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit affects expression EXP Orphenadrine affects the expression of JUN mRNA CTD PMID:23665939 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit affects expression EXP Orphenadrine affects the expression of JUNB mRNA CTD PMID:23665939 NCBI chr19:23,176,265...23,178,049
Ensembl chr19:23,176,294...23,178,035
JBrowse link
G Ka11 type I keratin KA11 affects expression EXP Orphenadrine affects the expression of KA11 mRNA CTD PMID:23665939 NCBI chr10:85,161,424...85,164,737 JBrowse link
G Kank2 KN motif and ankyrin repeat domains 2 affects expression EXP Orphenadrine affects the expression of KANK2 mRNA CTD PMID:23665939 NCBI chr 8:20,311,676...20,341,107
Ensembl chr 8:20,311,676...20,340,900
JBrowse link
G Kcnj15 potassium inwardly-rectifying channel, subfamily J, member 15 affects expression EXP Orphenadrine affects the expression of KCNJ15 mRNA CTD PMID:23665939 NCBI chr11:34,577,397...34,621,725
Ensembl chr11:34,577,363...34,621,952
JBrowse link
G Kcnk5 potassium two pore domain channel subfamily K member 5 affects expression EXP Orphenadrine affects the expression of KCNK5 mRNA CTD PMID:23665939 NCBI chr15:4,122,442...4,164,718
Ensembl chr15:4,122,442...4,164,718
JBrowse link
G Klf10 Kruppel-like factor 10 affects expression EXP Orphenadrine affects the expression of KLF10 mRNA CTD PMID:23665939 NCBI chr 7:69,467,658...69,473,726
Ensembl chr 7:69,465,619...69,473,994
JBrowse link
G Klhl21 kelch-like family member 21 affects expression EXP Orphenadrine affects the expression of KLHL21 mRNA CTD PMID:23665939 NCBI chr 5:162,514,888...162,523,545
Ensembl chr 5:162,514,765...162,523,545
JBrowse link
G Kmo kynurenine 3-monooxygenase affects expression EXP Orphenadrine affects the expression of KMO mRNA CTD PMID:23665939 NCBI chr13:87,557,080...87,589,334
Ensembl chr13:87,557,286...87,588,881
JBrowse link
G Krt10 keratin 10 affects expression EXP Orphenadrine affects the expression of KRT10 mRNA CTD PMID:23665939 NCBI chr10:84,338,695...84,343,279
Ensembl chr10:84,338,706...84,343,701
JBrowse link
G Krt8 keratin 8 affects expression EXP Orphenadrine affects the expression of KRT8 mRNA CTD PMID:23665939 NCBI chr 7:133,124,203...133,131,656
Ensembl chr 7:133,124,203...133,131,728
JBrowse link
G Lag3 lymphocyte activating 3 affects expression EXP Orphenadrine affects the expression of LAG3 mRNA CTD PMID:23665939 NCBI chr 4:157,712,665...157,722,229
Ensembl chr 4:157,712,667...157,720,404
JBrowse link
G Lekr1 leucine, glutamate and lysine rich 1 affects expression EXP Orphenadrine affects the expression of LEKR1 mRNA CTD PMID:23665939 NCBI chr 2:149,889,615...150,061,167
Ensembl chr 2:149,891,106...150,060,469
JBrowse link
G Lgals2 galectin 2 affects expression EXP Orphenadrine affects the expression of LGALS2 mRNA CTD PMID:23665939 NCBI chr 7:110,403,171...110,410,046
Ensembl chr 7:110,403,173...110,404,802
JBrowse link
G Lhx8 LIM homeobox 8 affects expression EXP Orphenadrine affects the expression of LHX8 mRNA CTD PMID:23665939 NCBI chr 2:243,244,958...243,269,631
Ensembl chr 2:243,244,961...243,269,416
JBrowse link
G Lilrb4 leukocyte immunoglobulin like receptor B4 affects expression EXP Orphenadrine affects the expression of LILRB4 mRNA CTD PMID:23665939 NCBI chr 1:69,805,020...69,810,628
Ensembl chr 1:69,805,250...69,810,660
JBrowse link
G Lin7a lin-7 homolog A, crumbs cell polarity complex component affects expression EXP Orphenadrine affects the expression of LIN7A mRNA CTD PMID:23665939 NCBI chr 7:42,586,704...42,742,609
Ensembl chr 7:42,586,719...42,730,550
JBrowse link
G Lmod2 leiomodin 2 affects expression EXP Orphenadrine affects the expression of LMOD2 mRNA CTD PMID:23665939 NCBI chr 4:53,067,428...53,075,124
Ensembl chr 4:53,067,428...53,075,120
JBrowse link
G Loxl4 lysyl oxidase-like 4 affects expression EXP Orphenadrine affects the expression of LOXL4 mRNA CTD PMID:23665939 NCBI chr 1:241,396,183...241,416,385
Ensembl chr 1:241,397,983...241,416,322
JBrowse link
G Lpcat4 lysophosphatidylcholine acyltransferase 4 affects expression EXP Orphenadrine affects the expression of LPCAT4 mRNA CTD PMID:23665939 NCBI chr 3:99,044,729...99,052,963
Ensembl chr 3:99,044,729...99,052,875
JBrowse link
G Lpin2 lipin 2 affects expression EXP Orphenadrine affects the expression of LPIN2 mRNA CTD PMID:23665939 NCBI chr 9:111,083,378...111,158,193
Ensembl chr 9:111,083,745...111,158,193
JBrowse link
G Lpl lipoprotein lipase affects expression EXP Orphenadrine affects the expression of LPL mRNA CTD PMID:23665939 NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249
JBrowse link
G Lrrn4 leucine rich repeat neuronal 4 affects expression EXP Orphenadrine affects the expression of LRRN4 mRNA CTD PMID:23665939 NCBI chr 3:120,138,093...120,150,877
Ensembl chr 3:120,139,410...120,150,831
JBrowse link
G Ltc4s leukotriene C4 synthase affects expression EXP Orphenadrine affects the expression of LTC4S mRNA CTD PMID:23665939 NCBI chr10:34,560,476...34,562,790
Ensembl chr10:34,560,360...34,562,651
JBrowse link
G Mafb MAF bZIP transcription factor B affects expression EXP Orphenadrine affects the expression of MAFB mRNA CTD PMID:23665939 NCBI chr 3:148,998,111...149,000,031
Ensembl chr 3:148,998,122...149,000,031
JBrowse link
G Magee1 MAGE family member E1 affects expression EXP Orphenadrine affects the expression of MAGEE1 mRNA CTD PMID:23665939 NCBI chr  X:70,189,242...70,192,789
Ensembl chr  X:70,189,187...70,192,810
JBrowse link
G Map1s microtubule-associated protein 1S affects expression EXP Orphenadrine affects the expression of MAP1S mRNA CTD PMID:23665939 NCBI chr16:18,516,759...18,527,777
Ensembl chr16:18,517,574...18,527,988
JBrowse link
G Map4k2 mitogen activated protein kinase kinase kinase kinase 2 affects expression EXP Orphenadrine affects the expression of MAP4K2 mRNA CTD PMID:23665939 NCBI chr 1:203,645,098...203,660,515
Ensembl chr 1:203,645,153...203,660,331
JBrowse link
G Map4k4 mitogen-activated protein kinase kinase kinase kinase 4 affects expression EXP Orphenadrine affects the expression of MAP4K4 mRNA CTD PMID:23665939 NCBI chr 9:42,200,708...42,326,708
Ensembl chr 9:42,200,278...42,326,698
JBrowse link
G Mapk12 mitogen-activated protein kinase 12 affects expression EXP Orphenadrine affects the expression of MAPK12 mRNA CTD PMID:23665939 NCBI chr 7:120,206,005...120,216,711
Ensembl chr 7:120,206,271...120,216,664
JBrowse link
G Matn4 matrilin 4 affects expression EXP Orphenadrine affects the expression of MATN4 mRNA CTD PMID:23665939 NCBI chr 3:153,120,605...153,135,628
Ensembl chr 3:153,120,632...153,135,865
JBrowse link
G Mcam melanoma cell adhesion molecule affects expression EXP Orphenadrine affects the expression of MCAM mRNA CTD PMID:23665939 NCBI chr 8:44,479,391...44,487,575
Ensembl chr 8:44,479,376...44,487,571
JBrowse link
G Metap1d methionyl aminopeptidase type 1D (mitochondrial) affects expression EXP Orphenadrine affects the expression of METAP1D mRNA CTD PMID:23665939 NCBI chr 3:56,279,471...56,354,518
Ensembl chr 3:56,279,493...56,351,981
JBrowse link
G Mex3b mex-3 RNA binding family member B affects expression EXP Orphenadrine affects the expression of MEX3B mRNA CTD PMID:23665939 NCBI chr 1:136,855,130...136,859,365
Ensembl chr 1:136,855,130...136,859,354
JBrowse link
G Mex3d mex-3 RNA binding family member D affects expression EXP Orphenadrine affects the expression of MEX3D mRNA CTD PMID:23665939 NCBI chr 7:9,325,575...9,332,705
Ensembl chr 7:9,325,488...9,332,096
JBrowse link
G Mfge8 milk fat globule EGF and factor V/VIII domain containing affects expression EXP Orphenadrine affects the expression of MFGE8 mRNA CTD PMID:23665939 NCBI chr 1:133,064,665...133,080,069
Ensembl chr 1:133,064,665...133,080,073
JBrowse link
G Mid1 midline 1 affects expression EXP Orphenadrine affects the expression of MID1 mRNA CTD PMID:23665939 NCBI chr  X:24,116,674...24,491,205
Ensembl chr  X:24,120,293...24,248,353
JBrowse link
G Mid1ip1 MID1 interacting protein 1 affects expression EXP Orphenadrine affects the expression of MID1IP1 mRNA CTD PMID:23665939 NCBI chr  X:12,060,993...12,063,318
Ensembl chr  X:12,060,883...12,065,774
JBrowse link
G Midn midnolin affects expression EXP Orphenadrine affects the expression of MIDN mRNA CTD PMID:23665939 NCBI chr 7:9,548,100...9,559,605
Ensembl chr 7:9,549,650...9,559,752
JBrowse link
G Mknk2 MAPK interacting serine/threonine kinase 2 affects expression EXP Orphenadrine affects the expression of MKNK2 mRNA CTD PMID:23665939 NCBI chr 7:9,039,771...9,050,832
Ensembl chr 7:9,039,728...9,050,827
JBrowse link
G Mlxip MLX interacting protein affects expression EXP Orphenadrine affects the expression of MLXIP mRNA CTD PMID:23665939 NCBI chr12:33,128,524...33,192,300
Ensembl chr12:33,128,520...33,192,374
JBrowse link
G Mmd monocyte to macrophage differentiation-associated affects expression EXP Orphenadrine affects the expression of MMD mRNA CTD PMID:23665939 NCBI chr10:75,073,278...75,101,528
Ensembl chr10:75,073,365...75,101,528
JBrowse link
G Mmp12 matrix metallopeptidase 12 affects expression EXP Orphenadrine affects the expression of MMP12 mRNA CTD PMID:23665939 NCBI chr 8:4,581,785...4,591,687
Ensembl chr 8:4,581,785...4,599,611
JBrowse link
G Mmp15 matrix metallopeptidase 15 affects expression EXP Orphenadrine affects the expression of MMP15 mRNA CTD PMID:23665939 NCBI chr19:9,663,449...9,684,943
Ensembl chr19:9,663,449...9,684,943
JBrowse link
G Mras muscle RAS oncogene homolog affects expression EXP Orphenadrine affects the expression of MRAS mRNA CTD PMID:23665939 NCBI chr 8:99,944,036...100,006,771
Ensembl chr 8:99,944,036...99,996,408
JBrowse link
G Mroh2a maestro heat-like repeat family member 2A affects expression EXP Orphenadrine affects the expression of MROH2A mRNA CTD PMID:23665939 NCBI chr 9:88,814,515...88,862,346
Ensembl chr 9:88,814,197...88,852,607
JBrowse link
G Mst1r macrophage stimulating 1 receptor affects expression EXP Orphenadrine affects the expression of MST1R mRNA CTD PMID:23665939 NCBI chr 8:108,596,100...108,611,389
Ensembl chr 8:108,597,299...108,612,455
JBrowse link
G Mtmr7 myotubularin related protein 7 affects expression EXP Orphenadrine affects the expression of MTMR7 mRNA CTD PMID:23665939 NCBI chr16:51,641,225...51,732,212
Ensembl chr16:51,641,190...51,732,182
JBrowse link
G Mtss2 MTSS I-BAR domain containing 2 affects expression EXP Orphenadrine affects the expression of MTSS2 mRNA CTD PMID:23665939 NCBI chr19:38,692,793...38,714,575
Ensembl chr19:38,693,194...38,713,507
JBrowse link
G Mx1 MX dynamin like GTPase 1 affects expression EXP Orphenadrine affects the expression of MX2 mRNA CTD PMID:23665939 NCBI chr11:36,799,659...36,825,209
Ensembl chr11:36,799,660...36,823,507
JBrowse link
G Mybph myosin binding protein H affects expression EXP Orphenadrine affects the expression of MYBPH mRNA CTD PMID:23665939 NCBI chr13:45,653,156...45,660,893
Ensembl chr13:45,653,234...45,660,893
JBrowse link
G Mypop Myb-related transcription factor, partner of profilin affects expression EXP Orphenadrine affects the expression of MYPOP mRNA CTD PMID:23665939 NCBI chr 1:78,639,694...78,650,555
Ensembl chr 1:78,639,769...78,650,552
JBrowse link
G Myrf myelin regulatory factor affects expression EXP Orphenadrine affects the expression of MYRF mRNA CTD PMID:23665939 NCBI chr 1:206,854,175...206,886,276
Ensembl chr 1:206,854,175...206,886,157
JBrowse link
G Nat8f2 N-acetyltransferase 8 (GCN5-related) family member 2 affects expression EXP Orphenadrine affects the expression of NAT8F2 mRNA CTD PMID:23665939 NCBI chr 4:118,319,984...118,323,159
Ensembl chr 4:118,319,988...118,324,395
JBrowse link
G Ncaph non-SMC condensin I complex, subunit H affects expression EXP Orphenadrine affects the expression of NCAPH mRNA CTD PMID:23665939 NCBI chr 3:114,371,937...114,399,223
Ensembl chr 3:114,371,941...114,399,180
JBrowse link
G Ncoa7 nuclear receptor coactivator 7 affects expression EXP Orphenadrine affects the expression of NCOA7 mRNA CTD PMID:23665939 NCBI chr 1:26,856,228...27,016,950
Ensembl chr 1:26,856,530...27,015,871
JBrowse link
G Nefh neurofilament heavy chain affects expression EXP Orphenadrine affects the expression of NEFH mRNA CTD PMID:22954530 NCBI chr14:79,830,362...79,840,347
Ensembl chr14:79,830,362...79,840,351
JBrowse link
G Neurl3 neuralized E3 ubiquitin protein ligase 3 affects expression EXP Orphenadrine affects the expression of NEURL3 mRNA CTD PMID:23665939 NCBI chr 9:38,494,486...38,503,352
Ensembl chr 9:38,494,489...38,502,649
JBrowse link
G Nfkbiz NFKB inhibitor zeta affects expression EXP Orphenadrine affects the expression of NFKBIZ mRNA CTD PMID:23665939 NCBI chr11:44,782,676...44,810,723
Ensembl chr11:44,782,676...44,810,723
JBrowse link
G Ninj2 ninjurin 2 affects expression EXP Orphenadrine affects the expression of NINJ2 mRNA CTD PMID:23665939 NCBI chr 4:153,306,439...153,408,618
Ensembl chr 4:153,306,553...153,408,617
JBrowse link
G Nipal2 NIPA-like domain containing 2 affects expression EXP Orphenadrine affects the expression of NIPAL2 mRNA CTD PMID:23665939 NCBI chr 7:65,774,477...65,884,807
Ensembl chr 7:65,774,477...65,884,807
JBrowse link
G Nlrc4 NLR family, CARD domain containing 4 affects expression EXP Orphenadrine affects the expression of NLRC4 mRNA CTD PMID:23665939 NCBI chr 6:20,991,785...21,018,254
Ensembl chr 6:20,995,266...21,018,248
JBrowse link
G Noct nocturnin affects expression EXP Orphenadrine affects the expression of NOCT mRNA CTD PMID:23665939 NCBI chr 2:135,271,189...135,291,407
Ensembl chr 2:135,271,189...135,291,400
JBrowse link
G Nos1ap nitric oxide synthase 1 adaptor protein affects expression EXP Orphenadrine affects the expression of NOS1AP mRNA CTD PMID:23665939 NCBI chr13:82,549,786...82,820,949 JBrowse link
G Nos3 nitric oxide synthase 3 affects expression EXP Orphenadrine affects the expression of NOS3 mRNA CTD PMID:23665939 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
JBrowse link
G Npy neuropeptide Y affects expression EXP Orphenadrine affects the expression of NPY mRNA CTD PMID:23665939 NCBI chr 4:78,881,294...78,888,495
Ensembl chr 4:78,881,264...78,888,495
JBrowse link
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 affects expression EXP Orphenadrine affects the expression of NR1D1 mRNA CTD PMID:23665939 NCBI chr10:83,728,348...83,735,562
Ensembl chr10:83,728,318...83,735,705
JBrowse link
G Nrep neuronal regeneration related protein affects expression EXP Orphenadrine affects the expression of NREP mRNA CTD PMID:23665939 NCBI chr18:25,017,069...25,046,564
Ensembl chr18:25,017,083...25,046,591
JBrowse link
G Nrg1 neuregulin 1 affects expression EXP Orphenadrine affects the expression of NRG1 mRNA CTD PMID:23665939 NCBI chr16:59,250,658...60,303,024
Ensembl chr16:59,250,854...60,296,884
JBrowse link
G Nrxn1 neurexin 1 affects expression EXP Orphenadrine affects the expression of NRXN1 mRNA CTD PMID:23665939 NCBI chr 6:3,177,788...4,323,848
Ensembl chr 6:3,177,897...4,322,710
JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator affects expression EXP Orphenadrine affects the expression of NUPR1 mRNA CTD PMID:23665939 NCBI chr 1:181,213,292...181,215,327 JBrowse link
G Oat ornithine aminotransferase affects expression EXP Orphenadrine affects the expression of OAT mRNA CTD PMID:23665939 NCBI chr 1:187,347,862...187,367,644
Ensembl chr 1:187,347,865...187,367,682
JBrowse link
G Ogn osteoglycin affects expression EXP Orphenadrine affects the expression of OGN mRNA CTD PMID:23665939 NCBI chr17:15,032,069...15,052,626
Ensembl chr17:15,032,069...15,052,739
JBrowse link
G Olr1198 olfactory receptor 1198 affects expression EXP Orphenadrine affects the expression of OLR1198 mRNA CTD PMID:23665939 NCBI chr 8:37,575,356...37,576,285
Ensembl chr 8:37,574,531...37,576,995