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ONTOLOGY REPORT - ANNOTATIONS


Term:esoxybutynin
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Accession:CHEBI:51329 term browser browse the term
Definition:A 4-(diethylamino)but-2-yn-1-ol yhat has S configuration. In contrast to the (R)- enantiomer, esoxybutynin exhibits essentially no anticholinergic activity.
Synonyms:exact_synonym: 4-(diethylamino)but-2-yn-1-yl (2S)-cyclohexyl(hydroxy)phenylacetate
 related_synonym: (+)-oxybutynin;   (S)-oxybutynin;   Formula=C22H31NO3;   InChI=1S/C22H31NO3/c1-3-23(4-2)17-11-12-18-26-21(24)22(25,19-13-7-5-8-14-19)20-15-9-6-10-16-20/h5,7-8,13-14,20,25H,3-4,6,9-10,15-18H2,1-2H3/t22-/m1/s1;   InChIKey=XIQVNETUBQGFHX-JOCHJYFZSA-N;   SMILES=C1(CCCCC1)[C@](C2=CC=CC=C2)(C(OCC#CCN(CC)CC)=O)O;   esoxibutinina;   esoxybutynine;   esoxybutyninum
 xref: CAS:119618-22-3;   PMID:10987980;   PMID:12001823;   PMID:12431028;   PMID:24036364;   PMID:25215879;   PMID:26852022
 cyclic_relationship: is_enantiomer_of CHEBI:144552


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oxybutynin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcb11 ATP binding cassette subfamily B member 11 JBrowse link 3 55,480,024 55,587,946 RGD:6480464
G Abcb4 ATP binding cassette subfamily B member 4 JBrowse link 4 22,133,984 22,192,687 RGD:6480464
G Ces2h carboxylesterase 2H JBrowse link 19 37,052,555 37,067,176 RGD:6480464
G Chrm2 cholinergic receptor, muscarinic 2 JBrowse link 4 64,089,028 64,091,090 RGD:6480464
G Chrm3 cholinergic receptor, muscarinic 3 JBrowse link 17 63,990,599 64,463,222 RGD:6480464
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 JBrowse link 1 147,236,480 147,307,988 RGD:6480464
G Drd2 dopamine receptor D2 JBrowse link 8 53,678,777 53,743,643 RGD:6480464
G Jun Jun proto-oncogene, AP-1 transcription factor subunit JBrowse link 5 114,011,184 114,014,277 RGD:6480464
G Slc22a2 solute carrier family 22 member 2 JBrowse link 1 48,318,025 48,360,219 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19770
    role 19717
      application 19366
        pharmaceutical 19236
          drug 19236
            anaesthetic 5197
              local anaesthetic 2956
                esoxybutynin 9
                  esoxybutynin chloride 0
                  oxybutynin + 9
Path 2
Term Annotations click to browse term
  CHEBI ontology 19770
    subatomic particle 19768
      composite particle 19768
        hadron 19768
          baryon 19768
            nucleon 19768
              atomic nucleus 19768
                atom 19768
                  main group element atom 19653
                    main group molecular entity 19653
                      s-block molecular entity 19415
                        hydrogen molecular entity 19404
                          hydrides 18360
                            inorganic hydride 17215
                              pnictogen hydride 17178
                                nitrogen hydride 17012
                                  azane 16707
                                    ammonia 16706
                                      organic amino compound 16705
                                        tertiary amino compound 8611
                                          4-(diethylamino)but-2-yn-1-ol 9
                                            esoxybutynin 9
                                              esoxybutynin chloride 0
                                              oxybutynin + 9
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.