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ONTOLOGY REPORT - ANNOTATIONS


Term:flurazepam
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Accession:CHEBI:5128 term browser browse the term
Definition:A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a 2-(diethylamino)ethyl group, 2-fluorophenyl group and chloro group at positions 1, 5 and 7, respectively. It is a partial agonist of GABAA receptors and used for the treatment of insomnia.
Synonyms:exact_synonym: 7-chloro-1-[2-(diethylamino)ethyl]-5-(2-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one
 related_synonym: Formula=C21H23ClFN3O;   InChI=1S/C21H23ClFN3O/c1-3-25(4-2)11-12-26-19-10-9-15(22)13-17(19)21(24-14-20(26)27)16-7-5-6-8-18(16)23/h5-10,13H,3-4,11-12,14H2,1-2H3;   InChIKey=SAADBVWGJQAEFS-UHFFFAOYSA-N;   Insumin;   Ro 5-6901;   SMILES=C(CN(CC)CC)N1C=2C(C(=NCC1=O)C3=CC=CC=C3F)=CC(=CC2)Cl;   flurazepamum
 xref: CAS:17617-23-1 "ChemIDplus";   CAS:17617-23-1 "KEGG COMPOUND";   CAS:17617-23-1 "NIST Chemistry WebBook";   DrugBank:DB00690;   Drug_Central:1218 "DrugCentral";   HMDB:HMDB0014828;   KEGG:D00329
 xref_mesh: MESH:D005479
 xref: PDBeChem:FL7;   PMID:16501350 "Europe PMC";   PMID:20002022 "Europe PMC";   PMID:23035248 "Europe PMC";   PMID:2863335 "Europe PMC";   Wikipedia:Flurazepam


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flurazepam term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gabra1 gamma-aminobutyric acid type A receptor alpha1 subunit JBrowse link 10 27,310,718 27,371,802 RGD:6480464
G Gabrb2 gamma-aminobutyric acid type A receptor beta 2 subunit JBrowse link 10 27,973,694 28,193,072 RGD:6480464
G Kcnh2 potassium voltage-gated channel subfamily H member 2 JBrowse link 4 7,355,066 7,387,282 RGD:6480464
G Trh thyrotropin releasing hormone JBrowse link 4 124,110,716 124,113,242 RGD:6480464
G Trhr thyrotropin releasing hormone receptor JBrowse link 7 83,113,641 83,153,520 RGD:6480464

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Term Annotations click to browse term
  CHEBI ontology 19669
    role 19613
      application 19235
        refrigerant 16994
          ammonia 16561
            organic amino compound 16560
              tertiary amino compound 8521
                flurazepam 5
                  hydroxyethylflurazepam 0
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Term Annotations click to browse term
  CHEBI ontology 19669
    subatomic particle 19665
      composite particle 19665
        hadron 19665
          baryon 19665
            nucleon 19665
              atomic nucleus 19665
                atom 19665
                  main group element atom 19545
                    main group molecular entity 19545
                      s-block molecular entity 19329
                        hydrogen molecular entity 19319
                          hydrides 18242
                            inorganic hydride 17104
                              pnictogen hydride 17062
                                nitrogen hydride 16885
                                  azane 16564
                                    ammonia 16561
                                      organic amino compound 16560
                                        tertiary amino compound 8521
                                          flurazepam 5
                                            hydroxyethylflurazepam 0
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