Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:propidium
go back to main search page
Accession:CHEBI:51246 term browser browse the term
Definition:A phenanthridine that has formula 414.58582.
Synonyms:exact_synonym: 3,8-diamino-5-{3-[diethyl(methyl)ammonio]propyl}-6-phenylphenanthridinium
 related_synonym: 3,8-DIAMINO-5[3-(DIETHYLMETHYLAMMONIO)PROPYL]-6-PHENYLPHENANTHRIDINIUM;   Formula=C27H34N4;   InChI=1S/C27H33N4/c1-4-31(3,5-2)17-9-16-30-26-19-22(29)13-15-24(26)23-14-12-21(28)18-25(23)27(30)20-10-7-6-8-11-20/h6-8,10-15,18-19,29H,4-5,9,16-17,28H2,1-3H3/q+1/p+1;   InChIKey=ZDWVWKDAWBGPDN-UHFFFAOYSA-O;   SMILES=CC[N+](C)(CC)CCC[n+]1c(-c2ccccc2)c2cc(N)ccc2c2ccc(N)cc12
 alt_id: CHEBI:45031;   CHEBI:51242
 xref: Beilstein:3729792;   CAS:36015-30-2;   DrugBank:DB02166;   LINCS:LSM-5329
 xref_mesh: MESH:D011419
 xref: PDBeChem:PRM



show annotations for term's descendants           Sort by:
 
propidium term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase multiple interactions
decreases activity
ISO Propidium binds to and results in decreased activity of ACHE protein; Propidium promotes the reaction [Dichlorvos results in increased phosphorylation of ACHE protein]; Propidium promotes the reaction [haloxon results in increased phosphorylation of ACHE protein]; Propidium promotes the reaction [Paraoxon results in increased phosphorylation of ACHE protein]
Propidium results in decreased activity of ACHE protein
CTD PMID:10421444 PMID:25522658 PMID:27238725 NCBI chr12:19,407,359...19,413,713
Ensembl chr12:19,407,360...19,413,651
JBrowse link
G Bche butyrylcholinesterase decreases activity ISO Propidium results in decreased activity of BCHE protein CTD PMID:31173753 NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases expression ISO Propidium results in decreased expression of CCL2 protein CTD PMID:20116850 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 decreases expression ISO Propidium results in decreased expression of CCL3 protein CTD PMID:20116850 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
JBrowse link
G Ccl4 C-C motif chemokine ligand 4 decreases expression ISO Propidium results in decreased expression of CCL4 protein CTD PMID:20116850 NCBI chr10:68,466,469...68,467,941
Ensembl chr10:68,452,052...68,468,231
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 decreases expression ISO Propidium results in decreased expression of CCL5 protein CTD PMID:20116850 NCBI chr10:68,322,826...68,327,365
Ensembl chr10:68,322,829...68,327,377
JBrowse link
G Il6r interleukin 6 receptor decreases expression ISO Propidium results in decreased expression of IL6R protein modified form CTD PMID:20116850 NCBI chr 2:175,289,157...175,347,719
Ensembl chr 2:175,298,686...175,347,536
JBrowse link
G Vegfa vascular endothelial growth factor A decreases expression ISO Propidium results in decreased expression of VEGFA protein CTD PMID:20116850 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20089
    role 20042
      application 19781
        dye 1366
          fluorescent dye 469
            fluorochrome 223
              propidium 8
                propidium iodide 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 20089
    subatomic particle 20058
      composite particle 20058
        hadron 20088
          baryon 20088
            nucleon 20088
              atomic nucleus 20088
                atom 20058
                  main group element atom 19960
                    p-block element atom 19990
                      carbon group element atom 19916
                        carbon atom 19909
                          organic molecular entity 19909
                            organic molecule 19856
                              organic cyclic compound 19612
                                organic heterocyclic compound 18824
                                  organic heteropolycyclic compound 18298
                                    organic heterotricyclic compound 15598
                                      dibenzopyridine 155
                                        phenanthridines 51
                                          propidium 8
                                            propidium iodide 0
paths to the root