Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes QTLs Strains Markers Genome Information Ontologies Cell Lines References FTP Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) RatMine GViewer (Genome Viewer) Overgo Probe Designer ACP Haplotyper Genome Scanner
Aging & Age-Related Disease Cancer Cardiovascular Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Genetic Models PhenoMiner (Quantitative Phenotypes) Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

ONTOLOGY REPORT - ANNOTATIONS
Term:fluphenazine
go back to main search page
Accession:CHEBI:5123 term browser browse the term
Definition:A member of the class of phenothiazines that is 10H-phenothiazine having a trifluoromethyl subsitituent at the 2-position and a 3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl group at the N-10 position.
Synonyms:exact_synonym: 2-(4-{3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl}piperazin-1-yl)ethan-1-ol
 related_synonym: 1-(2-hydroxyethyl)-4-(3-(trifluoromethyl-10-phenothiazinyl)propyl)-piperazine;   10-(3'-(4''-(beta-hydroxyethyl)-1''-piperazinyl)-propyl)-3-trifluoromethylphenothiazine;   10-(3-(2-hydroxyethyl)piperazinopropyl)-2-(trifluoromethyl)phenothiazine;   2-(4-(3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl)-1-piperazinyl)ethanol;   2-(trifluoromethyl)-10-(3-(1-(beta-hydroxyethyl)-4-piperazinyl)propyl)phenothiazine;   4-(3-(-trifluoromethyl-10-phenothiazyl)-propyl)-1-piperazineethanol;   4-(3-(2-(trifluoromethyl)-10H-phenothiazin-10-yl)propyl)-1-piperazineethanol;   4-(3-(2-trifluoromethyl-10-phenothiazyl)-propyl)-1-piperazineethanol;   Fluorfenazine;   Fluorophenazine;   Fluorphenazine;   Formula=C22H26F3N3OS;   InChI=1S/C22H26F3N3OS/c23-22(24,25)17-6-7-21-19(16-17)28(18-4-1-2-5-20(18)30-21)9-3-8-26-10-12-27(13-11-26)14-15-29/h1-2,4-7,16,29H,3,8-15H2;   InChIKey=PLDUPXSUYLZYBN-UHFFFAOYSA-N;   SMILES=OCCN1CCN(CCCN2c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1;   Triflumethazine;   flufenazina;   fluphenazinum
 xref: Beilstein:1189506 "Beilstein";   Beilstein:61643 "Beilstein";   CAS:69-23-8 "ChemIDplus";   CAS:69-23-8 "KEGG COMPOUND";   CAS:69-23-8 "NIST Chemistry WebBook";   DrugBank:DB00623;   Drug_Central:1212 "DrugCentral";   Gmelin:1231182 "Gmelin";   HMDB:HMDB0014761;   KEGG:C07010;   KEGG:D07977;   LINCS:LSM-3226
 xref_mesh: MESH:D005476
 xref: PMID:13950763 "Europe PMC";   PMID:16117689 "Europe PMC";   PMID:1650428 "Europe PMC";   PMID:16839522 "Europe PMC";   PMID:25595294 "Europe PMC";   PMID:5128930 "Europe PMC";   Patent:GB829246;   Patent:GB833474;   Patent:US3058979;   Patent:US3194733;   Reaxys:61643 "Reaxys";   Wikipedia:Fluphenazine

show annotations for term's descendants       view all columns           Sort by:
 
fluphenazine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Alad aminolevulinate dehydratase JBrowse link 5 78,368,867 78,379,206 RGD:6480464
G Ar androgen receptor JBrowse link X 67,656,253 67,828,998 RGD:6480464
G Cat catalase JBrowse link 3 93,379,872 93,412,058 RGD:6480464
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 JBrowse link 1 147,713,879 147,814,410 RGD:6480464
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 JBrowse link 1 213,511,892 213,522,195 RGD:6480464
G Drd2 dopamine receptor D2 JBrowse link 8 53,678,777 53,743,643 RGD:6480464
G Htr2a 5-hydroxytryptamine receptor 2A JBrowse link 15 56,666,152 56,732,469 RGD:6480464
G Htr2c 5-hydroxytryptamine receptor 2C JBrowse link X 118,084,520 118,318,040 RGD:6480464
G Ngf nerve growth factor JBrowse link 2 204,886,158 204,939,523 RGD:6480464
G Prl prolactin JBrowse link 17 39,814,236 39,824,299 RGD:6480464
G Slc22a2 solute carrier family 22 member 2 JBrowse link 1 48,318,025 48,360,219 RGD:6480464
G Tac1 tachykinin, precursor 1 JBrowse link 4 33,638,853 33,646,819 RGD:6480464
G Tfeb transcription factor EB JBrowse link 9 15,208,141 15,264,101 RGD:6480464
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19716
    role 19663
      biological role 19661
        pharmacological role 18755
          neurotransmitter agent 16393
            dopaminergic agent 5041
              dopaminergic antagonist 1166
                fluphenazine 13
                  fluphenazine decanoate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19716
    subatomic particle 19712
      composite particle 19712
        hadron 19712
          baryon 19712
            nucleon 19712
              atomic nucleus 19712
                atom 19712
                  main group element atom 19598
                    p-block element atom 19598
                      carbon group element atom 19486
                        carbon atom 19480
                          organic molecular entity 19480
                            organic molecule 19402
                              organic cyclic compound 19158
                                organic heterocyclic compound 18245
                                  organic heteropolycyclic compound 17500
                                    organic heterotricyclic compound 13738
                                      mancude organic heterotricyclic parent 344
                                        phenothiazine 26
                                          10H-phenothiazine 26
                                            fluphenazine 13
                                              fluphenazine decanoate 0
paths to the root

Contact Us |  About Us |  License CC BY 4.0 |  Legal Disclaimer |  © Medical College of Wisconsin
NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.