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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:xanthones
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Accession:CHEBI:51149 term browser browse the term
Definition:Any member of the class of xanthenes based on a xanthone skeleton.
Synonyms:xref_mesh: MESH:D044004



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xanthones term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO Xanthones inhibits the reaction [Lipopolysaccharides results in increased expression of FOS protein] CTD PMID:21232528 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Irak1 interleukin-1 receptor-associated kinase 1 multiple interactions ISO Xanthones inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased ubiquitination of and results in increased degradation of IRAK1 protein] CTD PMID:21232528 NCBI chr  X:151,768,621...151,778,521
Ensembl chr  X:151,768,777...151,778,521
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO Xanthones inhibits the reaction [Lipopolysaccharides results in increased expression of JUN protein] CTD PMID:21232528 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO Xanthones inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein] CTD PMID:21232528 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO Xanthones inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein] CTD PMID:21232528 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO Xanthones inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] CTD PMID:21232528 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
alpha-mangostin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aifm1 apoptosis inducing factor, mitochondria associated 1 affects localization ISO mangostin affects the localization of AIFM1 protein CTD PMID:24480042 NCBI chr  X:127,650,223...127,689,356
Ensembl chr  X:127,650,226...127,689,256
JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases phosphorylation ISO mangostin results in decreased phosphorylation of AKT1 protein CTD PMID:23954321 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
multiple interactions
ISO mangostin results in increased expression of BAX protein
mangostin inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of BAX mRNA]
CTD PMID:24480042 PMID:26357513 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
multiple interactions
ISO mangostin results in decreased expression of BCL2 protein
mangostin inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of BCL2 mRNA]
CTD PMID:24480042 PMID:26357513 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bid BH3 interacting domain death agonist decreases expression ISO mangostin results in decreased expression of BID protein CTD PMID:24480042 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
JBrowse link
G Casp3 caspase 3 multiple interactions ISO mangostin inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased activity of CASP3 protein] CTD PMID:26357513 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp7 caspase 7 multiple interactions
increases activity
ISO ESR1 protein affects the reaction [mangostin results in increased activity of CASP7 protein] CTD PMID:24480042 NCBI chr 1:255,437,195...255,476,737
Ensembl chr 1:255,437,172...255,476,729
JBrowse link
G Casp8 caspase 8 increases activity ISO mangostin results in increased activity of CASP8 protein CTD PMID:24480042 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 increases activity ISO mangostin results in increased activity of CASP9 protein CTD PMID:23954321 PMID:24480042 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cycs cytochrome c, somatic increases expression ISO mangostin results in increased expression of CYCS protein CTD PMID:24480042 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions
decreases expression
affects response to substance
ISO ESR1 protein affects the reaction [mangostin results in increased activity of CASP7 protein]
mangostin results in decreased expression of ESR1 protein
ESR1 protein affects the susceptibility to mangostin
CTD PMID:24480042 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 increases phosphorylation ISO mangostin analog results in increased phosphorylation of MAP2K1 protein CTD PMID:28722351 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147
JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 increases phosphorylation ISO mangostin analog results in increased phosphorylation of MAP2K2 protein CTD PMID:28722351 NCBI chr 7:8,590,729...8,610,279
Ensembl chr 7:8,580,905...8,610,243
JBrowse link
G Map2k4 mitogen activated protein kinase kinase 4 increases phosphorylation ISO mangostin analog results in increased phosphorylation of MAP2K4 protein CTD PMID:28722351 NCBI chr10:50,343,227...50,447,956
Ensembl chr10:50,344,915...50,447,993
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation
ISO mangostin results in decreased expression of and results in decreased phosphorylation of MAPK1 protein
mangostin analog results in increased phosphorylation of MAPK1 protein
CTD PMID:23954321 PMID:28722351 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation
ISO mangostin results in decreased expression of and results in decreased phosphorylation of MAPK3 protein
mangostin analog results in increased phosphorylation of MAPK3 protein
CTD PMID:23954321 PMID:28722351 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases phosphorylation ISO mangostin analog results in increased phosphorylation of MAPK8 protein CTD PMID:28722351 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 increases phosphorylation ISO mangostin analog results in increased phosphorylation of MAPK9 protein CTD PMID:28722351 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions
decreases expression
ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [mangostin analog results in decreased expression of MMP2 protein]; pyrazolanthrone inhibits the reaction [mangostin analog results in decreased expression of MMP2 protein]
mangostin analog results in decreased expression of MMP2 mRNA; mangostin analog results in decreased expression of MMP2 protein
CTD PMID:28722351 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Mmp9 matrix metallopeptidase 9 decreases expression
multiple interactions
ISO mangostin analog results in decreased expression of MMP9 mRNA; mangostin analog results in decreased expression of MMP9 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [mangostin analog results in decreased expression of MMP9 protein]; pyrazolanthrone inhibits the reaction [mangostin analog results in decreased expression of MMP9 protein]
CTD PMID:28722351 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage ISO mangostin results in increased cleavage of PARP1 protein CTD PMID:23954321 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP mangostin inhibits the reaction [Isoproterenol results in increased expression of PTGS2 protein] CTD PMID:18424012 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Tff1 trefoil factor 1 decreases expression ISO mangostin results in decreased expression of TFF1 protein CTD PMID:24480042 NCBI chr20:9,235,736...9,239,597
Ensembl chr20:9,235,736...9,239,597
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP mangostin inhibits the reaction [Isoproterenol results in increased expression of TNF protein] CTD PMID:18424012 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tp53 tumor protein p53 increases expression
multiple interactions
ISO mangostin results in increased expression of TP53 protein
mangostin inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of TP53 mRNA]
CTD PMID:24480042 PMID:26357513 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
cudratricusxanthone A term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifnb1 interferon beta 1 multiple interactions ISO cudratricusxanthone A inhibits the reaction [Lipopolysaccharides results in increased secretion of IFNB1 protein] CTD PMID:31350693 NCBI chr 5:103,020,969...103,021,523
Ensembl chr 5:103,020,969...103,021,523
JBrowse link
G Irf3 interferon regulatory factor 3 multiple interactions ISO cudratricusxanthone A inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased expression of IRF3 protein] CTD PMID:31350693 NCBI chr 1:95,479,966...95,484,926
Ensembl chr 1:95,479,821...95,484,935
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO cudratricusxanthone A inhibits the reaction [Lipopolysaccharides affects the phosphorylation of and affects the expression of and affects the localization of JUN protein] CTD PMID:31350693 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO cudratricusxanthone A inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein] CTD PMID:31350693 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO cudratricusxanthone A inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein] CTD PMID:31350693 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor multiple interactions ISO cudratricusxanthone A inhibits the reaction [Lipopolysaccharides results in increased expression of MYD88 protein] CTD PMID:31350693 NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO cudratricusxanthone A inhibits the reaction [Lipopolysaccharides results in decreased expression of NFKBIA protein] CTD PMID:31350693 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO cudratricusxanthone A inhibits the reaction [Lipopolysaccharides affects the localization of RELA protein] CTD PMID:31350693 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Ticam1 toll-like receptor adaptor molecule 1 multiple interactions ISO cudratricusxanthone A inhibits the reaction [Lipopolysaccharides results in increased expression of TICAM1 protein] CTD PMID:31350693 NCBI chr 9:1,102,559...1,115,573 JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions ISO cudratricusxanthone A inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 protein] CTD PMID:31350693 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO cudratricusxanthone A inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein] CTD PMID:31350693 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
gamma-mangostin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta2 actin alpha 2, smooth muscle multiple interactions
decreases expression
ISO [gamma-mangostin co-treated with MK 2206] results in decreased expression of ACTA2 protein; diphenyleneiodonium promotes the reaction [gamma-mangostin results in decreased expression of ACTA2 protein]; gamma-mangostin promotes the reaction [diphenyleneiodonium results in decreased expression of ACTA2 protein]; SIRT3 protein affects the reaction [gamma-mangostin results in decreased expression of ACTA2 protein]
gamma-mangostin inhibits the reaction [Carbon Tetrachloride results in increased expression of ACTA2 protein]
CTD PMID:30502394 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions
decreases phosphorylation
ISO [gamma-mangostin co-treated with MK 2206] results in decreased phosphorylation of AKT1 protein
gamma-mangostin results in decreased phosphorylation of AKT1 protein
CTD PMID:30502394 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions ISO gamma-mangostin inhibits the reaction [Carbon Tetrachloride results in increased expression of GPT protein] CTD PMID:30502394 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G Hdac1 histone deacetylase 1 increases expression ISO gamma-mangostin results in increased expression of HDAC1 protein CTD PMID:30502394 NCBI chr 5:141,853,992...141,881,057
Ensembl chr 5:141,853,989...141,881,111
JBrowse link
G Hmgb1 high mobility group box 1 decreases secretion
multiple interactions
ISO gamma-mangostin results in decreased secretion of HMGB1 protein
diphenyleneiodonium promotes the reaction [gamma-mangostin results in decreased secretion of HMGB1 protein]; gamma-mangostin affects the localization of and results in decreased acetylation of HMGB1 protein; gamma-mangostin promotes the reaction [diphenyleneiodonium results in decreased secretion of HMGB1 protein]; SIRT3 protein affects the reaction [gamma-mangostin results in decreased secretion of HMGB1 protein]
gamma-mangostin inhibits the reaction [Carbon Tetrachloride results in increased expression of HMGB1 protein]
CTD PMID:30502394 NCBI chr12:5,973,062...5,978,565 JBrowse link
G Sirt3 sirtuin 3 multiple interactions
increases expression
ISO SIRT3 protein affects the reaction [gamma-mangostin results in decreased expression of ACTA2 protein]; SIRT3 protein affects the reaction [gamma-mangostin results in decreased secretion of HMGB1 protein]
gamma-mangostin results in increased expression of SIRT3 protein
[gamma-mangostin co-treated with Carbon Tetrachloride] results in increased expression of and results in increased secretion of SIRT3 protein
CTD PMID:30502394 NCBI chr 1:195,942,066...195,964,472
Ensembl chr 1:195,942,073...195,964,808
JBrowse link
mangiferin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A increases expression
multiple interactions
ISO mangiferin results in increased expression of ABCB1 mRNA; mangiferin results in increased expression of ABCB1 protein
Dichlororibofuranosylbenzimidazole inhibits the reaction [mangiferin results in increased expression of ABCB1 protein]
CTD PMID:20513373 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase decreases expression ISO mangiferin results in decreased expression of ABL1 mRNA CTD PMID:15498116 NCBI chr 3:14,979,853...15,083,065
Ensembl chr 3:14,979,853...15,083,065
JBrowse link
G Acaca acetyl-CoA carboxylase alpha multiple interactions
increases phosphorylation
EXP dorsomorphin inhibits the reaction [mangiferin results in increased phosphorylation of ACACA protein] CTD PMID:22292039 NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457
JBrowse link
G Ache acetylcholinesterase multiple interactions
decreases activity
ISO mangiferin inhibits the reaction [Scopolamine results in decreased expression of ACHE protein]
mangiferin results in decreased activity of ACHE protein
CTD PMID:19182383 PMID:22426032 NCBI chr12:19,407,359...19,413,713
Ensembl chr12:19,407,360...19,413,651
JBrowse link
G Acp5 acid phosphatase 5, tartrate resistant multiple interactions ISO mangiferin inhibits the reaction [TNFSF11 protein results in increased expression of ACP5 mRNA] CTD PMID:20683903 NCBI chr 8:20,663,984...20,670,604
Ensembl chr 8:20,663,985...20,667,929
JBrowse link
G Adrb3 adrenoceptor beta 3 multiple interactions ISO [mangiferin co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of ADRB3 protein CTD PMID:32417366 NCBI chr16:64,839,820...64,844,552
Ensembl chr16:64,841,788...64,844,552
JBrowse link
G Ager advanced glycosylation end product-specific receptor decreases expression EXP mangiferin results in decreased expression of AGER mRNA; mangiferin results in decreased expression of AGER protein CTD PMID:24036348 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078
JBrowse link
G Agt angiotensinogen multiple interactions EXP mangiferin inhibits the reaction [AGT protein results in decreased expression of PLAU mRNA]; mangiferin inhibits the reaction [AGT protein results in increased expression of AGTR1A mRNA]; mangiferin inhibits the reaction [AGT protein results in increased expression of AGTR1A protein]; mangiferin inhibits the reaction [AGT protein results in increased expression of COL1A1 mRNA]; mangiferin inhibits the reaction [AGT protein results in increased expression of COL4A1 mRNA]; mangiferin inhibits the reaction [AGT protein results in increased expression of FN1 mRNA]; mangiferin inhibits the reaction [AGT protein results in increased expression of FN1 protein]; mangiferin inhibits the reaction [AGT protein results in increased expression of SERPINE1 mRNA]; mangiferin inhibits the reaction [AGT protein results in increased expression of TGFB1 mRNA]; mangiferin inhibits the reaction [AGT protein results in increased expression of TGFB1 protein] CTD PMID:17645561 PMID:19706694 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
JBrowse link
G Agtr1a angiotensin II receptor, type 1a multiple interactions EXP mangiferin inhibits the reaction [AGT protein results in increased expression of AGTR1A mRNA]; mangiferin inhibits the reaction [AGT protein results in increased expression of AGTR1A protein] CTD PMID:17645561 PMID:19706694 NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946
JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 multiple interactions EXP mangiferin inhibits the reaction [Excitatory Amino Acid Agonists affects the localization of AIFM1 protein] CTD PMID:19201465 NCBI chr  X:127,650,223...127,689,356
Ensembl chr  X:127,650,226...127,689,256
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions EXP
ISO
mangiferin inhibits the reaction [Excitatory Amino Acid Agonists results in decreased phosphorylation of AKT1 protein]
mangiferin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of AKT1 protein]
CTD PMID:19201465 PMID:22465218 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Alb albumin affects binding ISO mangiferin binds to ALB protein CTD PMID:19157745 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 multiple interactions ISO mangiferin inhibits the reaction [lead nitrate results in decreased expression of APAF1 protein] CTD PMID:23451106 NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540
JBrowse link
G Atp6v0d2 ATPase H+ transporting V0 subunit D2 multiple interactions ISO mangiferin inhibits the reaction [TNFSF11 protein results in increased expression of ATP6V0D2 mRNA] CTD PMID:20683903 NCBI chr 5:33,336,257...33,385,354
Ensembl chr 5:33,336,264...33,385,354
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions EXP
ISO
mangiferin inhibits the reaction [Excitatory Amino Acid Agonists results in increased expression of BAX protein]
mangiferin inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of BAX protein]; mangiferin inhibits the reaction [lead nitrate results in increased expression of BAX protein]
CTD PMID:19201465 PMID:23451106 PMID:24095822 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO
EXP
mangiferin inhibits the reaction [TNF protein results in increased expression of BCL2 mRNA]
mangiferin inhibits the reaction [Galactosamine results in decreased expression of BCL2 protein]
mangiferin inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of BCL2 protein]; mangiferin inhibits the reaction [lead nitrate results in decreased expression of BCL2 protein]
CTD PMID:21420233 PMID:22118634 PMID:23451106 PMID:24095822 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression ISO mangiferin results in decreased expression of BCL2L1 protein CTD PMID:21547680 PMID:26996543 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases expression ISO mangiferin results in decreased expression of BIRC5 protein CTD PMID:26996543 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
JBrowse link
G C3 complement C3 decreases expression ISO mangiferin results in decreased expression of C3 mRNA CTD PMID:15135318 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429
JBrowse link
G Calcr calcitonin receptor multiple interactions ISO mangiferin inhibits the reaction [TNFSF11 protein results in increased expression of CALCR mRNA] CTD PMID:20683903 NCBI chr 4:31,661,270...31,736,392
Ensembl chr 4:31,661,273...31,736,392
JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
ISO
EXP
mangiferin inhibits the reaction [lead nitrate results in increased expression of CASP3 protein]
mangiferin results in increased activity of CASP3 protein
mangiferin inhibits the reaction [Galactosamine results in increased expression of CASP3 protein]
CTD PMID:21547680 PMID:22118634 PMID:22310181 PMID:23451106 PMID:26996543 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp8 caspase 8 increases expression ISO mangiferin results in increased expression of CASP8 protein CTD PMID:32420661 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 multiple interactions ISO
EXP
mangiferin inhibits the reaction [lead nitrate results in increased expression of CASP9 protein]
mangiferin inhibits the reaction [Galactosamine results in increased expression of CASP9 protein]
CTD PMID:22118634 PMID:23451106 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cat catalase multiple interactions
increases activity
ISO
EXP
mangiferin inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of CAT mRNA]; mangiferin inhibits the reaction [Benzo(a)pyrene results in decreased activity of CAT protein]; mangiferin inhibits the reaction [Dextran Sulfate results in decreased activity of CAT protein]; mangiferin inhibits the reaction [lead nitrate results in decreased activity of CAT protein]
mangiferin inhibits the reaction [Mercuric Chloride results in decreased expression of CAT protein]
mangiferin inhibits the reaction [Cyclophosphamide results in decreased activity of CAT protein]; mangiferin inhibits the reaction [Excitatory Amino Acid Agonists results in decreased activity of CAT protein]; mangiferin inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; mangiferin inhibits the reaction [Streptozocin results in decreased activity of CAT protein]
mangiferin results in increased activity of CAT protein
CTD PMID:15161907 PMID:16076520 PMID:16584858 PMID:16697266 PMID:17433543 More... NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases expression ISO mangiferin results in decreased expression of CCL2 mRNA CTD PMID:15135318 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 multiple interactions ISO mangiferin inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of CCL5 protein] CTD PMID:15135318 NCBI chr10:68,322,826...68,327,365
Ensembl chr10:68,322,829...68,327,377
JBrowse link
G Ccnb1 cyclin B1 increases expression ISO mangiferin results in increased expression of CCNB1 mRNA CTD PMID:20518311 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
JBrowse link
G Cd36 CD36 molecule multiple interactions
increases expression
EXP dorsomorphin inhibits the reaction [mangiferin results in increased expression of CD36 protein] CTD PMID:22292039 NCBI chr 4:17,317,343...17,410,084 JBrowse link
G Cdh1 cadherin 1 increases expression
affects expression
multiple interactions
ISO mangiferin results in increased expression of CDH1 protein
mangiferin affects the expression of CDH1 protein
lipopolysaccharide, Escherichia coli O111 B4 affects the reaction [mangiferin affects the expression of CDH1 protein]
CTD PMID:23707762 PMID:32420661 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
JBrowse link
G Cdk1 cyclin-dependent kinase 1 increases expression ISO mangiferin results in increased expression of CDK1 mRNA CTD PMID:20518311 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex multiple interactions ISO
EXP
mangiferin inhibits the reaction [TNF protein results in increased phosphorylation of CHUK protein]
mangiferin inhibits the reaction [lead nitrate results in increased phosphorylation of CHUK protein]
mangiferin inhibits the reaction [Galactosamine results in increased phosphorylation of CHUK protein]
CTD PMID:21420233 PMID:22310181 PMID:23451106 NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065
JBrowse link
G Cidea cell death-inducing DFFA-like effector a multiple interactions ISO [mangiferin co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CIDEA mRNA CTD PMID:32417366 NCBI chr18:60,894,917...60,920,485
Ensembl chr18:60,894,874...60,920,481
JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions EXP mangiferin inhibits the reaction [AGT protein results in increased expression of COL1A1 mRNA] CTD PMID:19706694 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Col4a1 collagen type IV alpha 1 chain multiple interactions EXP mangiferin inhibits the reaction [AGT protein results in increased expression of COL4A1 mRNA] CTD PMID:19706694 NCBI chr16:78,183,533...78,294,412
Ensembl chr16:78,183,533...78,294,412
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A increases expression
multiple interactions
EXP mangiferin results in increased expression of CPT1A protein
dorsomorphin inhibits the reaction [mangiferin results in increased expression of CPT1A protein]
CTD PMID:22292039 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
JBrowse link
G Csf2 colony stimulating factor 2 multiple interactions
decreases expression
ISO mangiferin inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of CSF2 protein]
mangiferin results in decreased expression of CSF2 mRNA
CTD PMID:15135318 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
JBrowse link
G Csf3 colony stimulating factor 3 multiple interactions
decreases expression
ISO mangiferin inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of CSF3 protein]
mangiferin results in decreased expression of CSF3 mRNA
CTD PMID:15135318 NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603
JBrowse link
G Ctnnb1 catenin beta 1 decreases response to substance ISO CTNNB1 protein results in decreased susceptibility to mangiferin CTD PMID:23707762 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Ctnnd1 catenin delta 1 multiple interactions ISO mangiferin inhibits the reaction [Paraquat results in decreased expression of and affects the localization of CTNND1 protein]; mangiferin inhibits the reaction [Paraquat results in decreased expression of CTNND1 mRNA alternative form] CTD PMID:24912632 NCBI chr 3:69,683,328...69,734,550
Ensembl chr 3:69,683,313...69,734,516
JBrowse link
G Ctsd cathepsin D multiple interactions EXP mangiferin inhibits the reaction [Isoproterenol results in decreased activity of CTSD protein] CTD PMID:19172585 NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488
JBrowse link
G Ctsk cathepsin K multiple interactions ISO mangiferin inhibits the reaction [TNFSF11 protein results in increased expression of CTSK mRNA] CTD PMID:20683903 NCBI chr 2:183,058,586...183,069,551
Ensembl chr 2:183,058,569...183,069,550
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 multiple interactions ISO mangiferin affects the reaction [lipopolysaccharide, Escherichia coli O111 B4 affects the expression of CXCR4 protein]; mangiferin inhibits the reaction [TNF protein results in increased expression of CXCR4 mRNA] CTD PMID:21420233 PMID:32420661 NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression ISO mangiferin results in increased expression of CYP1A1 mRNA CTD PMID:22815239 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases activity
increases expression
EXP
ISO
mangiferin results in decreased activity of CYP1A2 protein
mangiferin results in increased expression of CYP1A2 mRNA
CTD PMID:18053976 PMID:22815239 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 increases activity EXP mangiferin results in increased activity of CYP2B1 protein CTD PMID:18053976 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
JBrowse link
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 decreases activity EXP mangiferin results in decreased activity of CYP2C6V1 protein CTD PMID:18053976 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 decreases activity ISO mangiferin results in decreased activity of CYP2D6 protein CTD PMID:22815239 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases activity EXP mangiferin results in decreased activity of CYP2E1 protein CTD PMID:18053976 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 decreases activity ISO mangiferin results in decreased activity of CYP3A4 protein CTD PMID:22815239 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 decreases activity EXP mangiferin results in decreased activity of CYP3A23-3A1 protein CTD PMID:18053976 NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030
JBrowse link
G Dcstamp dendrocyte expressed seven transmembrane protein multiple interactions ISO mangiferin inhibits the reaction [TNFSF11 protein results in increased expression of DCSTAMP mRNA] CTD PMID:20683903 NCBI chr 7:70,807,455...70,822,067
Ensembl chr 7:70,807,581...70,822,078
JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 decreases expression
affects expression
multiple interactions
EXP mangiferin results in decreased expression of DGAT2 protein
mangiferin affects the expression of DGAT2 mRNA; mangiferin affects the expression of DGAT2 protein
dorsomorphin inhibits the reaction [mangiferin results in increased expression of DGAT2 protein]
CTD PMID:22292039 PMID:25123789 NCBI chr 1:153,454,078...153,484,432
Ensembl chr 1:153,454,080...153,484,428
JBrowse link
G Dnm1l dynamin 1-like multiple interactions ISO mangiferin inhibits the reaction [Methylmercury Compounds results in increased expression of and results in increased phosphorylation of DNM1L protein] CTD PMID:28071871 NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482
JBrowse link
G F10 coagulation factor X decreases activity ISO mangiferin analog results in decreased activity of F10 protein CTD PMID:21732671 NCBI chr16:76,468,834...76,488,141
Ensembl chr16:76,468,838...76,488,141
JBrowse link
G Fas Fas cell surface death receptor increases expression ISO mangiferin results in increased expression of FAS protein CTD PMID:17634039 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Fbp1 fructose-bisphosphatase 1 decreases expression ISO mangiferin results in decreased expression of FBP1 mRNA CTD PMID:19028559 NCBI chr17:2,207,271...2,230,076
Ensembl chr17:2,208,031...2,230,071
JBrowse link
G Fn1 fibronectin 1 multiple interactions EXP mangiferin inhibits the reaction [AGT protein results in increased expression of FN1 mRNA]; mangiferin inhibits the reaction [AGT protein results in increased expression of FN1 protein] CTD PMID:19706694 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
JBrowse link
G Gcg glucagon multiple interactions EXP [mangiferin co-treated with Sitagliptin Phosphate] results in increased expression of GCG protein alternative form CTD PMID:22948814 NCBI chr 3:47,113,914...47,122,929
Ensembl chr 3:47,113,914...47,122,929
JBrowse link
G Glo1 glyoxalase 1 increases expression
multiple interactions
EXP mangiferin results in increased expression of GLO1 mRNA
mangiferin results in increased expression of and results in increased activity of GLO1 protein
CTD PMID:24036348 NCBI chr20:8,663,617...8,681,661
Ensembl chr20:8,662,801...8,681,649
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions EXP mangiferin inhibits the reaction [Streptozocin results in increased activity of GPT protein] CTD PMID:29223569 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions ISO
EXP
mangiferin inhibits the reaction [Benzo(a)pyrene results in decreased activity of GSR protein]; mangiferin inhibits the reaction [lead nitrate results in decreased activity of GSR protein]
mangiferin inhibits the reaction [Methylmercury Compounds results in decreased activity of GSR protein]
mangiferin inhibits the reaction [Isoproterenol results in decreased activity of GSR protein]
CTD PMID:16697266 PMID:18816296 PMID:23451106 PMID:28071871 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Gusb glucuronidase, beta multiple interactions EXP mangiferin inhibits the reaction [Isoproterenol results in decreased activity of GUSB protein] CTD PMID:19172585 NCBI chr12:26,701,191...26,714,718
Ensembl chr12:26,697,951...26,726,905
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions EXP mangiferin inhibits the reaction [Galactosamine results in decreased expression of HMOX1 protein] CTD PMID:22310181 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions
decreases expression
ISO mangiferin inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]
mangiferin results in decreased expression of ICAM1 mRNA
CTD PMID:15135318 PMID:15161907 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Icam2 intercellular adhesion molecule 2 decreases expression ISO mangiferin results in decreased expression of ICAM2 mRNA CTD PMID:15135318 NCBI chr10:91,308,608...91,319,536
Ensembl chr10:91,308,538...91,315,293
JBrowse link
G Icam5 intercellular adhesion molecule 5 decreases expression ISO mangiferin results in decreased expression of ICAM5 mRNA CTD PMID:15135318 NCBI chr 8:19,567,390...19,575,588
Ensembl chr 8:19,568,600...19,575,588
JBrowse link
G Ifnb1 interferon beta 1 increases expression ISO mangiferin results in increased expression of IFNB1 mRNA CTD PMID:15135318 NCBI chr 5:103,020,969...103,021,523
Ensembl chr 5:103,020,969...103,021,523
JBrowse link
G Ifng interferon gamma multiple interactions ISO
EXP
mangiferin inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased abundance of Dinoprostone]; mangiferin inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased abundance of Leukotriene B4]; mangiferin inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased abundance of Nitric Oxide]; mangiferin inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of CCL5 protein]; mangiferin inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of CSF2 protein]; mangiferin inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of CSF3 protein]; mangiferin inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL6 protein]; mangiferin inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; mangiferin inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of TNF mRNA]; mangiferin inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of TNF protein]; mangiferin inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased secretion of TNF protein]; mangiferin promotes the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of TGFB1 mRNA]
mangiferin inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; mangiferin inhibits the reaction [Galactosamine results in increased expression of IFNG mRNA]
CTD PMID:12694877 PMID:15135318 PMID:15177302 PMID:15177305 PMID:15222974 More... NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta multiple interactions ISO
EXP
mangiferin inhibits the reaction [TNF protein results in increased phosphorylation of IKBKB protein]
mangiferin inhibits the reaction [Galactosamine results in increased phosphorylation of IKBKB protein]
CTD PMID:21420233 PMID:22310181 NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250
JBrowse link
G Il10 interleukin 10 multiple interactions EXP mangiferin inhibits the reaction [Galactosamine results in decreased expression of IL10 mRNA] CTD PMID:22310181 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il12a interleukin 12A decreases expression ISO mangiferin results in decreased expression of IL12A mRNA CTD PMID:15135318 NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734
JBrowse link
G Il12b interleukin 12B multiple interactions EXP mangiferin inhibits the reaction [Galactosamine results in increased expression of IL12B mRNA] CTD PMID:22310181 NCBI chr10:28,888,832...28,903,796
Ensembl chr10:28,893,008...28,902,903
JBrowse link
G Il18 interleukin 18 multiple interactions EXP mangiferin inhibits the reaction [Galactosamine results in increased expression of IL18 mRNA] CTD PMID:22310181 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
JBrowse link
G Il1a interleukin 1 alpha decreases expression ISO mangiferin results in decreased expression of IL1A mRNA CTD PMID:15135318 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP
ISO
mangiferin inhibits the reaction [Galactosamine results in increased expression of IL1B mRNA]; mangiferin inhibits the reaction [IL1B protein results in increased expression of NOS2 mRNA]; mangiferin inhibits the reaction [IL1B protein results in increased expression of PTGS2 mRNA]
mangiferin analog inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of IL1B protein]; mangiferin inhibits the reaction [Dextran Sulfate results in increased expression of IL1B protein]
CTD PMID:15381052 PMID:22310181 PMID:27125760 PMID:27474068 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il2rb interleukin 2 receptor subunit beta decreases expression ISO mangiferin results in decreased expression of IL2RB mRNA CTD PMID:15135318 NCBI chr 7:110,033,341...110,048,054
Ensembl chr 7:110,033,341...110,048,054
JBrowse link
G Il6 interleukin 6 multiple interactions
decreases expression
ISO
EXP
mangiferin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of IL6 protein]; mangiferin inhibits the reaction [TNF protein results in increased expression of IL6 mRNA]; mangiferin inhibits the reaction [TNF protein results in increased secretion of IL6 protein]
mangiferin inhibits the reaction [Galactosamine results in increased expression of IL6 mRNA]
mangiferin analog inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of IL6 protein]; mangiferin inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL6 protein]; mangiferin inhibits the reaction [Ketamine results in increased expression of IL6 protein]
mangiferin results in decreased expression of IL6 mRNA
CTD PMID:15135318 PMID:21420233 PMID:22310181 PMID:23087136 PMID:27474068 More... NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Irf1 interferon regulatory factor 1 decreases expression ISO mangiferin results in decreased expression of IRF1 mRNA CTD PMID:15135318 NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166
JBrowse link
G Lpl lipoprotein lipase multiple interactions
increases activity
increases expression
ISO MK-886 inhibits the reaction [mangiferin results in increased activity of LPL protein]; MK-886 inhibits the reaction [mangiferin results in increased expression of LPL mRNA] CTD PMID:15975614 NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249
JBrowse link
G Map3k14 mitogen-activated protein kinase kinase kinase 14 decreases phosphorylation ISO mangiferin results in decreased phosphorylation of MAP3K14 protein CTD PMID:26996543 NCBI chr10:88,165,349...88,215,558
Ensembl chr10:88,165,351...88,215,523
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation
decreases activity
affects binding
multiple interactions
ISO
EXP
mangiferin results in increased phosphorylation of MAPK1 protein
mangiferin metabolite results in decreased activity of MAPK1 protein
mangiferin metabolite binds to MAPK1 protein
mangiferin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]
mangiferin inhibits the reaction [Excitatory Amino Acid Agonists results in increased phosphorylation of MAPK1 protein]
mangiferin analog inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK1 protein]; mangiferin inhibits the reaction [lead nitrate results in increased phosphorylation of MAPK1 protein]; mangiferin inhibits the reaction [TNFSF11 protein results in increased phosphorylation of MAPK1 protein]
CTD PMID:19201465 PMID:20683903 PMID:22084399 PMID:22465218 PMID:23451106 More... NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
decreases activity
increases phosphorylation
ISO
EXP
mangiferin analog inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK3 protein]; mangiferin inhibits the reaction [lead nitrate results in increased phosphorylation of MAPK3 protein]; mangiferin inhibits the reaction [TNFSF11 protein results in increased phosphorylation of MAPK3 protein]
mangiferin metabolite results in decreased activity of MAPK3 protein
mangiferin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]
mangiferin inhibits the reaction [Excitatory Amino Acid Agonists results in increased phosphorylation of MAPK3 protein]
mangiferin results in increased phosphorylation of MAPK3 protein
CTD PMID:19201465 PMID:20683903 PMID:22084399 PMID:22465218 PMID:23451106 More... NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 decreases expression ISO mangiferin results in decreased expression of MAPK8 mRNA CTD PMID:15135318 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 decreases expression ISO mangiferin results in decreased expression of MAPK9 mRNA CTD PMID:15135318 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178
JBrowse link
G Max MYC associated factor X decreases expression ISO mangiferin results in decreased expression of MAX mRNA CTD PMID:15135318 NCBI chr 6:95,636,857...95,662,204
Ensembl chr 6:95,636,858...95,662,137
JBrowse link
G Mmp7 matrix metallopeptidase 7 decreases expression ISO mangiferin results in decreased expression of MMP7 protein CTD PMID:23707762 NCBI chr 8:4,848,186...4,855,908
Ensembl chr 8:4,848,186...4,855,902
JBrowse link
G Mmp9 matrix metallopeptidase 9 decreases expression
multiple interactions
decreases activity
ISO mangiferin results in decreased expression of MMP9 mRNA; mangiferin results in decreased expression of MMP9 protein
mangiferin inhibits the reaction [Dextran Sulfate results in increased expression of MMP9 protein]
mangiferin results in decreased expression of and results in decreased secretion of MMP9 protein
mangiferin results in decreased activity of MMP9 protein
CTD PMID:22465218 PMID:23707762 PMID:27125760 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Mpo myeloperoxidase multiple interactions ISO mangiferin inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein] CTD PMID:27125760 NCBI chr10:72,594,458...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions EXP mangiferin affects the reaction [Galactosamine affects the localization of NFE2L2 protein]; mangiferin inhibits the reaction [Galactosamine results in decreased expression of NFE2L2 protein] CTD PMID:22310181 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO mangiferin inhibits the reaction [TNF protein affects the localization of and results in increased activity of NFKB1 protein] CTD PMID:15161907 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions
increases expression
ISO
EXP
mangiferin inhibits the reaction [TNF protein results in increased phosphorylation of and results in increased degradation of NFKBIA protein]
mangiferin inhibits the reaction [Galactosamine results in decreased expression of NFKBIA protein]
mangiferin results in increased expression of NFKBIA protein
mangiferin analog inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in decreased expression of NFKBIA protein]; mangiferin inhibits the reaction [lead nitrate results in decreased expression of NFKBIA protein]; mangiferin inhibits the reaction [TNFSF11 protein results in increased degradation of NFKBIA protein]
CTD PMID:15161907 PMID:20683903 PMID:22310181 PMID:23451106 PMID:27474068 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nfkbib NFKB inhibitor beta decreases expression
multiple interactions
ISO mangiferin results in decreased expression of NFKBIB mRNA
mangiferin inhibits the reaction [TNF protein results in increased degradation of NFKBIB protein]
CTD PMID:15135318 PMID:21420233 NCBI chr 1:84,046,292...84,053,862
Ensembl chr 1:84,046,295...84,053,862
JBrowse link
G Nfkbie NFKB inhibitor epsilon decreases expression ISO mangiferin results in decreased expression of NFKBIE mRNA CTD PMID:15135318 NCBI chr 9:15,443,600...15,450,437
Ensembl chr 9:15,436,941...15,450,437
JBrowse link
G Nfkbil1 NFKB inhibitor like 1 decreases expression ISO mangiferin results in decreased expression of NFKBIL1 mRNA CTD PMID:15135318 NCBI chr20:3,589,974...3,608,348
Ensembl chr20:3,590,642...3,605,616
JBrowse link
G Ngf nerve growth factor increases secretion ISO mangiferin results in increased secretion of NGF protein CTD PMID:20303935 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions ISO mangiferin affects the reaction [lipopolysaccharide, Escherichia coli O111 B4 affects the expression of NLRP3 protein] CTD PMID:32420661 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions EXP
ISO
mangiferin inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; mangiferin inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with TNF protein] results in increased expression of NOS2 mRNA]; mangiferin inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with TNF protein] results in increased secretion of NOS2 mRNA]; mangiferin inhibits the reaction [Galactosamine results in increased expression of NOS2 protein]; mangiferin inhibits the reaction [IL1B protein results in increased expression of NOS2 mRNA]; mangiferin promotes the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with TNFB protein] results in increased expression of NOS2 mRNA]
mangiferin analog inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of NOS2 protein]; mangiferin inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of NOS2 mRNA]
CTD PMID:12694877 PMID:15381052 PMID:22118634 PMID:22310181 PMID:27474068 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions EXP mangiferin inhibits the reaction [Galactosamine results in decreased expression of NQO1 protein] CTD PMID:22310181 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Per1 period circadian regulator 1 affects expression
multiple interactions
ISO mangiferin affects the expression of PER1 protein
mangiferin affects the reaction [lipopolysaccharide, Escherichia coli O111 B4 affects the expression of PER1 protein]
CTD PMID:32420661 NCBI chr10:53,800,126...53,814,963
Ensembl chr10:53,805,535...53,814,431
JBrowse link
G Pla2g2a phospholipase A2 group IIA decreases activity ISO mangiferin results in decreased activity of PLA2G2A protein CTD PMID:15177302 NCBI chr 5:151,076,442...151,079,019
Ensembl chr 5:151,076,442...151,079,014
JBrowse link
G Plau plasminogen activator, urokinase multiple interactions EXP mangiferin inhibits the reaction [AGT protein results in decreased expression of PLAU mRNA] CTD PMID:19706694 NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions
increases activity
ISO MK-886 inhibits the reaction [mangiferin results in increased activity of PPARA protein]
[mangiferin co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of PPARA mRNA
CTD PMID:15975614 PMID:32417366 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions EXP
ISO
mangiferin inhibits the reaction [Streptozocin results in decreased expression of PPARG mRNA]; mangiferin inhibits the reaction [Streptozocin results in decreased expression of PPARG protein]
[mangiferin co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of PPARG protein
CTD PMID:29223569 PMID:32417366 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha multiple interactions ISO [mangiferin co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of PPARGC1A mRNA; [mangiferin co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of PPARGC1A protein CTD PMID:32417366 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
JBrowse link
G Prdm16 PR/SET domain 16 multiple interactions ISO [mangiferin co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of PRDM16 mRNA; [mangiferin co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of PRDM16 protein CTD PMID:32417366 NCBI chr 5:164,879,864...165,203,986
Ensembl chr 5:164,880,587...165,203,601
JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 multiple interactions EXP dorsomorphin inhibits the reaction [mangiferin results in increased phosphorylation of and results in increased activity of PRKAA1 protein]; mangiferin results in increased phosphorylation of and results in increased activity of PRKAA1 protein CTD PMID:22292039 NCBI chr 2:54,240,298...54,275,978
Ensembl chr 2:54,240,137...54,275,978
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
affects expression
ISO
EXP
mangiferin inhibits the reaction [TNF protein results in increased expression of PTGS2 mRNA]
mangiferin analog inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of PTGS2 protein]
mangiferin inhibits the reaction [IL1B protein results in increased expression of PTGS2 mRNA]; mangiferin inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]
mangiferin affects the expression of PTGS2 mRNA
CTD PMID:15161907 PMID:15381052 PMID:18621015 PMID:19026997 PMID:21420233 More... NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase decreases expression ISO mangiferin results in decreased expression of RAF1 mRNA CTD PMID:15135318 NCBI chr 4:148,679,534...148,740,265
Ensembl chr 4:148,679,530...148,740,317
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
affects localization
decreases expression
decreases localization
ISO
EXP
mangiferin inhibits the reaction [TNF protein affects the localization of and results in increased phosphorylation of and results in increased activity of RELA protein]
mangiferin affects the localization of RELA protein
mangiferin inhibits the reaction [Excitatory Amino Acid Agonists affects the localization of and results in increased activity of RELA protein]; mangiferin inhibits the reaction [Galactosamine results in increased expression of RELA protein]
mangiferin results in decreased expression of RELA mRNA
mangiferin analog inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 affects the localization of RELA protein]; mangiferin inhibits the reaction [lead nitrate results in increased expression of RELA protein]; mangiferin inhibits the reaction [Scopolamine results in increased phosphorylation of and results in increased activity of RELA protein]; mangiferin inhibits the reaction [TNF protein results in increased phosphorylation of and results in increased activity of RELA protein]; mangiferin inhibits the reaction [TNFSF11 protein results in increased localization of RELA protein]
mangiferin results in decreased localization of RELA protein
CTD PMID:15135318 PMID:15161907 PMID:19182383 PMID:19201465 PMID:20683903 More... NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Relb RELB proto-oncogene, NF-kB subunit decreases expression ISO mangiferin results in decreased expression of RELB mRNA CTD PMID:15135318 NCBI chr 1:79,257,738...79,285,490
Ensembl chr 1:79,257,725...79,285,507
JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 decreases expression ISO mangiferin results in decreased expression of RIPK1 mRNA CTD PMID:15135318 NCBI chr17:30,839,639...30,871,824
Ensembl chr17:30,839,650...30,871,824
JBrowse link
G Sele selectin E decreases expression ISO mangiferin results in decreased expression of SELE mRNA CTD PMID:15135318 NCBI chr13:76,402,841...76,412,741
Ensembl chr13:76,403,304...76,412,741
JBrowse link
G Selplg selectin P ligand decreases expression ISO mangiferin results in decreased expression of SELPLG mRNA CTD PMID:15135318 NCBI chr12:42,796,690...42,809,908
Ensembl chr12:42,796,580...42,812,585
JBrowse link
G Serpine1 serpin family E member 1 multiple interactions EXP mangiferin inhibits the reaction [AGT protein results in increased expression of SERPINE1 mRNA] CTD PMID:19706694 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
JBrowse link
G Slc22a1 solute carrier family 22 member 1 increases expression ISO mangiferin results in increased expression of SLC22A1 mRNA CTD PMID:21348301 NCBI chr 1:48,076,657...48,103,679
Ensembl chr 1:48,076,666...48,103,678
JBrowse link
G Slc22a12 solute carrier family 22 member 12 decreases expression ISO mangiferin results in decreased expression of SLC22A12 mRNA; mangiferin results in decreased expression of SLC22A12 protein CTD PMID:21348301 NCBI chr 1:203,845,039...203,852,496
Ensembl chr 1:203,845,048...203,853,555
JBrowse link
G Slc22a2 solute carrier family 22 member 2 increases expression ISO mangiferin results in increased expression of SLC22A2 mRNA CTD PMID:21348301 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268
JBrowse link
G Slc22a4 solute carrier family 22 member 4 increases expression ISO mangiferin results in increased expression of SLC22A4 mRNA CTD PMID:21348301 NCBI chr10:38,133,333...38,179,932 JBrowse link
G Slc22a5 solute carrier family 22 member 5 increases expression ISO mangiferin results in increased expression of SLC22A5 mRNA CTD PMID:21348301 NCBI chr10:38,008,303...38,035,474
Ensembl chr10:38,008,311...38,035,309
JBrowse link
G Slc2a4 solute carrier family 2 member 4 multiple interactions
increases expression
ISO
EXP
2-chloro-5-nitrobenzanilide inhibits the reaction [mangiferin promotes the reaction [SLC2A4 protein results in increased uptake of Deoxyglucose]]; mangiferin affects the localization of and results in increased activity of SLC2A4 protein; mangiferin promotes the reaction [SLC2A4 protein results in increased uptake of Deoxyglucose]; mangiferin promotes the reaction [SLC2A4 protein results in increased uptake of Glucose]
mangiferin inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 mRNA]; mangiferin inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 protein]
mangiferin results in increased expression of SLC2A4 mRNA
CTD PMID:19477051 PMID:29223569 NCBI chr10:54,666,015...54,671,581
Ensembl chr10:54,666,015...54,671,565
JBrowse link
G Snai1 snail family transcriptional repressor 1 decreases expression ISO mangiferin results in decreased expression of SNAI1 protein CTD PMID:23707762 NCBI chr 3:156,248,479...156,252,969
Ensembl chr 3:156,248,485...156,252,969
JBrowse link
G Snai2 snail family transcriptional repressor 2 decreases expression ISO mangiferin results in decreased expression of SNAI2 protein CTD PMID:23707762 NCBI chr11:86,183,800...86,186,109
Ensembl chr11:86,181,909...86,186,200
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions ISO mangiferin inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of SOD1 mRNA] CTD PMID:17433543 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Srd5a2 steroid 5 alpha-reductase 2 decreases activity ISO mangiferin results in decreased activity of SRD5A2 protein CTD PMID:20823678 NCBI chr 6:21,426,225...21,465,727
Ensembl chr 6:21,426,215...21,462,112
JBrowse link
G Srf serum response factor decreases expression ISO mangiferin results in decreased expression of SRF mRNA CTD PMID:15135318 NCBI chr 9:14,426,453...14,435,734
Ensembl chr 9:14,426,472...14,435,733
JBrowse link
G Tab1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 decreases expression ISO mangiferin results in decreased expression of TAB1 mRNA CTD PMID:15135318 NCBI chr 7:111,675,829...111,707,058
Ensembl chr 7:111,686,371...111,707,058
JBrowse link
G Tbk1 TANK-binding kinase 1 decreases expression ISO mangiferin results in decreased expression of TBK1 mRNA CTD PMID:15135318 NCBI chr 7:57,077,830...57,110,868
Ensembl chr 7:57,077,830...57,110,892
JBrowse link
G Tert telomerase reverse transcriptase decreases activity ISO mangiferin results in decreased activity of TERT protein CTD PMID:17634039 NCBI chr 1:29,637,213...29,659,509
Ensembl chr 1:29,637,506...29,659,561
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO
EXP
mangiferin promotes the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of TGFB1 mRNA]
mangiferin inhibits the reaction [AGT protein results in increased expression of TGFB1 mRNA]; mangiferin inhibits the reaction [AGT protein results in increased expression of TGFB1 protein]; mangiferin inhibits the reaction [Streptozocin results in increased secretion of TGFB1 protein]
CTD PMID:12694877 PMID:19706694 PMID:19960420 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tlr6 toll-like receptor 6 decreases expression ISO mangiferin results in decreased expression of TLR6 mRNA CTD PMID:15135318 NCBI chr14:43,362,164...43,374,500
Ensembl chr14:43,362,164...43,375,685
JBrowse link
G Tlr7 toll-like receptor 7 decreases expression ISO mangiferin results in decreased expression of TLR7 mRNA CTD PMID:15135318 NCBI chr  X:27,027,380...27,054,309
Ensembl chr  X:27,027,425...27,054,754
JBrowse link
G Tlr8 toll-like receptor 8 decreases expression ISO mangiferin results in decreased expression of TLR8 mRNA CTD PMID:15135318 NCBI chr  X:27,091,780...27,116,092
Ensembl chr  X:27,091,778...27,116,549
JBrowse link
G Tlr9 toll-like receptor 9 decreases expression ISO mangiferin results in decreased expression of TLR9 mRNA CTD PMID:15135318 NCBI chr 8:106,864,680...106,868,796
Ensembl chr 8:106,864,680...106,868,796
JBrowse link
G Tnf tumor necrosis factor multiple interactions
decreases expression
affects expression
increases secretion
ISO
EXP
mangiferin inhibits the reaction [TNF protein affects the localization of and results in increased activity of NFKB1 protein]; mangiferin inhibits the reaction [TNF protein affects the localization of and results in increased phosphorylation of and results in increased activity of RELA protein]; mangiferin inhibits the reaction [TNF protein results in increased abundance of Reactive Oxygen Species]; mangiferin inhibits the reaction [TNF protein results in increased degradation of NFKBIB protein]; mangiferin inhibits the reaction [TNF protein results in increased expression of BCL2 mRNA]; mangiferin inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA]; mangiferin inhibits the reaction [TNF protein results in increased expression of CXCR4 mRNA]; mangiferin inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; mangiferin inhibits the reaction [TNF protein results in increased expression of IL6 mRNA]; mangiferin inhibits the reaction [TNF protein results in increased expression of PTGS2 mRNA]; mangiferin inhibits the reaction [TNF protein results in increased expression of VEGFA mRNA]; mangiferin inhibits the reaction [TNF protein results in increased expression of XIAP mRNA]; mangiferin inhibits the reaction [TNF protein results in increased phosphorylation of and results in increased degradation of NFKBIA protein]; mangiferin inhibits the reaction [TNF protein results in increased phosphorylation of CHUK protein]; mangiferin inhibits the reaction [TNF protein results in increased phosphorylation of IKBKB protein]; mangiferin inhibits the reaction [TNF protein results in increased secretion of CXCL8 protein]; mangiferin inhibits the reaction [TNF protein results in increased secretion of IL6 protein]
mangiferin inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with TNF protein] results in increased expression of NOS2 mRNA]; mangiferin inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with TNF protein] results in increased secretion of NOS2 mRNA]; mangiferin inhibits the reaction [Galactosamine results in increased expression of TNF mRNA]; mangiferin inhibits the reaction [Galactosamine results in increased expression of TNF protein]; mangiferin inhibits the reaction [Isoproterenol results in increased expression of TNF protein]
mangiferin results in decreased expression of TNF mRNA
mangiferin analog inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of TNF protein]; mangiferin inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of TNF mRNA]; mangiferin inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of TNF protein]; mangiferin inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased secretion of TNF protein]; mangiferin inhibits the reaction [Dextran Sulfate results in increased expression of TNF protein]; mangiferin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; mangiferin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; mangiferin inhibits the reaction [Scopolamine results in increased expression of TNF protein]; mangiferin inhibits the reaction [TNF protein results in increased phosphorylation of and results in increased activity of RELA protein]
mangiferin affects the expression of TNF protein
mangiferin results in increased secretion of TNF protein
CTD PMID:12694877 PMID:15135318 PMID:15161907 PMID:15177305 PMID:15222974 More... NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfrsf11a TNF receptor superfamily member 11A decreases expression ISO mangiferin results in decreased expression of TNFRSF11A mRNA CTD PMID:15135318 NCBI chr13:21,928,370...21,986,719
Ensembl chr13:21,928,408...21,986,695
JBrowse link
G Tnfsf11 TNF superfamily member 11 multiple interactions ISO mangiferin inhibits the reaction [TNFSF11 protein results in increased degradation of NFKBIA protein]; mangiferin inhibits the reaction [TNFSF11 protein results in increased expression of ACP5 mRNA]; mangiferin inhibits the reaction [TNFSF11 protein results in increased expression of ATP6V0D2 mRNA]; mangiferin inhibits the reaction [TNFSF11 protein results in increased expression of CALCR mRNA]; mangiferin inhibits the reaction [TNFSF11 protein results in increased expression of CTSK mRNA]; mangiferin inhibits the reaction [TNFSF11 protein results in increased expression of DCSTAMP mRNA]; mangiferin inhibits the reaction [TNFSF11 protein results in increased localization of RELA protein]; mangiferin inhibits the reaction [TNFSF11 protein results in increased phosphorylation of MAPK1 protein]; mangiferin inhibits the reaction [TNFSF11 protein results in increased phosphorylation of MAPK3 protein] CTD PMID:20683903 NCBI chr15:53,674,990...53,705,171
Ensembl chr15:53,673,877...53,705,445
JBrowse link
G Tp53 tumor protein p53 multiple interactions EXP mangiferin inhibits the reaction [Oxygen deficiency results in increased expression of TP53 protein] CTD PMID:10657591 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Tradd TNFRSF1A-associated via death domain decreases expression ISO mangiferin results in decreased expression of TRADD mRNA CTD PMID:15135318 NCBI chr19:33,136,148...33,142,714
Ensembl chr19:33,136,138...33,142,638
JBrowse link
G Traf6 TNF receptor associated factor 6 decreases expression ISO mangiferin results in decreased expression of TRAF6 mRNA CTD PMID:15135318 NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507
JBrowse link
G Ucp1 uncoupling protein 1 multiple interactions ISO [mangiferin co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of UCP1 protein CTD PMID:32417366 NCBI chr19:24,808,782...24,816,853
Ensembl chr19:24,808,783...24,816,852
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases expression
decreases activity
ISO mangiferin results in increased expression of UGT1A1 mRNA
mangiferin results in decreased activity of UGT1A1 protein
CTD PMID:22815239 NCBI chr 9:88,801,344...88,808,465 JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 increases expression ISO mangiferin results in increased expression of UGT1A9 mRNA CTD PMID:22815239 NCBI chr 9:88,696,981...88,808,465 JBrowse link
G Ugt2b7 UDP glucuronosyltransferase family 2 member B7 decreases activity ISO mangiferin results in decreased activity of UGT2B7 protein CTD PMID:22815239 NCBI chr14:20,896,682...20,919,604
Ensembl chr14:20,896,682...20,919,604
JBrowse link
G Umod uromodulin affects expression ISO mangiferin affects the expression of UMOD protein CTD PMID:21348301 NCBI chr 1:173,816,341...173,829,681
Ensembl chr 1:173,816,339...173,830,302
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 decreases expression ISO mangiferin results in decreased expression of VCAM1 mRNA CTD PMID:15135318 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO mangiferin inhibits the reaction [TNF protein results in increased expression of VEGFA mRNA] CTD PMID:21420233 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
G Vim vimentin decreases expression
multiple interactions
ISO mangiferin results in decreased expression of VIM protein
mangiferin affects the reaction [lipopolysaccharide, Escherichia coli O111 B4 affects the expression of VIM protein]
CTD PMID:23707762 PMID:32420661 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
JBrowse link
G Xiap X-linked inhibitor of apoptosis multiple interactions
decreases expression
ISO mangiferin inhibits the reaction [TNF protein results in increased expression of XIAP mRNA]
mangiferin results in decreased expression of XIAP protein
CTD PMID:21420233 PMID:21547680 PMID:26996543 NCBI chr  X:120,890,537...120,938,413
Ensembl chr  X:120,897,907...120,934,700
JBrowse link
norathyriol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A increases expression ISO norathyriol results in increased expression of ABCB1 protein CTD PMID:20513373 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Mapk1 mitogen activated protein kinase 1 affects binding
decreases activity
ISO norathyriol binds to MAPK1 protein
norathyriol results in decreased activity of MAPK1 protein
CTD PMID:22084399 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 decreases activity ISO norathyriol results in decreased activity of MAPK3 protein CTD PMID:22084399 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO norathyriol inhibits the reaction [GW 7647 results in increased activity of PPARA protein] CTD PMID:18393431 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Ppard peroxisome proliferator-activated receptor delta multiple interactions ISO norathyriol inhibits the reaction [GW0742 results in increased activity of PPARD protein] CTD PMID:18393431 NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO norathyriol inhibits the reaction [ciglitazone results in increased activity of PPARG protein] CTD PMID:18393431 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
psorospermin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions ISO psorospermin inhibits the reaction [ABCB1 protein results in decreased susceptibility to Doxorubicin] CTD PMID:7083125 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
vadimezan term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP binding cassette subfamily C member 1 affects export
affects transport
ISO ABCC1 protein affects the export of vadimezan metabolite
ABCC1 protein affects the transport of vadimezan analog
CTD PMID:15282097 PMID:15784341 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 affects transport
affects export
ISO ABCC2 protein affects the transport of vadimezan analog
ABCC2 protein affects the export of vadimezan metabolite
CTD PMID:15282097 PMID:15784341 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions
increases oxidation
ISO Acridines analog inhibits the reaction [CYP1A2 protein results in increased oxidation of vadimezan] CTD PMID:16120190 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Il1a interleukin 1 alpha increases expression EXP vadimezan results in increased expression of IL1A protein CTD PMID:16944150 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Il6 interleukin 6 increases expression EXP vadimezan results in increased expression of IL6 protein CTD PMID:16944150 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
ISO
EXP
TNF protein affects the reaction [vadimezan affects the metabolism of Thalidomide]
vadimezan results in increased expression of TNF protein
CTD PMID:15060740 PMID:16944150 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Vegfa vascular endothelial growth factor A increases expression EXP vadimezan results in increased expression of VEGFA protein CTD PMID:16944150 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
xanthone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace2 angiotensin I converting enzyme 2 multiple interactions EXP xanthone inhibits the reaction [LEP protein results in increased activity of ACE2 protein]; xanthone inhibits the reaction [LEP protein results in increased expression of ACE2] CTD PMID:25205467 NCBI chr  X:30,293,597...30,340,961
Ensembl chr  X:30,293,589...30,340,977
JBrowse link
G Lep leptin multiple interactions EXP xanthone inhibits the reaction [LEP protein results in increased activity of ACE2 protein]; xanthone inhibits the reaction [LEP protein results in increased expression of ACE2] CTD PMID:25205467 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19800
    chemical entity 19800
      group 19722
        inorganic group 19247
          oxo group 18651
            organic oxo compound 18651
              carbonyl compound 18651
                ketone 16957
                  cyclic ketone 15522
                    xanthones 174
                      (-)-microdiplodiasolol 0
                      (7R,8R)-AGI-B4 0
                      (7R,8R)-alpha-diversonolic ester 0
                      (E)-4-(3,7-Dimethyl-2,6-octadienyl)-1,3,5-trihydroxyxanthone 0
                      1,2,5-trihydroxyxanthone 0
                      1,3,5,6-tetrahydroxy-4,7,8-tri(3-methyl-2-butenyl)xanthone 0
                      1,3,5-trihydroxy-2-(2',2'-dimethyl-4'-isopropenyl)cyclopentanylxanthone 0
                      1,3,5-trihydroxyxanthone 0
                      1,3,6-Trihydroxy-5-methoxyxanthone 0
                      1,3,6-tri-O-methylarthothelin 0
                      1,3,7-trihydroxy-2,4-diisoprenylxanthone 0
                      1,3,8-trihydroxy-4-methyl-2,7-diprenylxanthone 0
                      1,3-dihydroxy-6-methoxy-8-methyl-9-xanthenone 0
                      1,4,5-Trihydroxy-3-prenylxanthone 0
                      1,4,6-Trihydroxy-5-methoxy-7-prenylxanthone 0
                      1,5,8-Trihydroxy-3-methyl-2-prenylxanthone 0
                      1,5-Dihydroxy-3-methoxy-2-prenylxanthone 0
                      1,6-Dihydroxy-3,7-dimethoxy-2-(3-methyl-2-butenyl)-8-(2-hydroxy-3-methyl-3-butenyl)-xanthone 0
                      1,6-Dihydroxy-3,7-dimethoxy-2-(3-methyl-2-butenyl)-8-(2-oxo-3-methyl-3-butenyl)-xanthone 0
                      1,6-Dihydroxy-3,8-dimethylxanthone 0
                      1,6-Dihydroxy-3-methoxy-2-prenylxanthone 0
                      1,7-Dihydroxy-3,6-dimethoxy-2,8-diprenylxanthone 0
                      1,7-Dihydroxy-3-methoxy-2-prenylxanthone 0
                      1,7-dihydroxy-4-methoxyxanthone 0
                      1,8-Dihydroxy-3,5-dimethoxy-2-prenylxanthone 0
                      1,8-dihydroxy-3-methoxy-6-methylxanthone 0
                      1,8-dihydroxy-4-nitroxanthen-9-one 0
                      1-Hydroxy-3,5-dimethoxy-2-prenylxanthone 0
                      1-Hydroxy-3,6,7-trimethoxy-2,8-diprenylxanthone 0
                      1-Hydroxy-3,6,7-trimethoxy-2-(2-hydroxy-3-methyl-3-butenyl)-8-(3-methyl-2-butenyl)-xanthone 0
                      1-Hydroxy-3,6,7-trimethoxy-2-(3-methyl-2-butenyl)-8-(2-hydroxy-3-methyl-3-butenyl)-xanthone 0
                      1-Hydroxy-3,6,7-trimethoxy-2-(3-methyl-2-butenyl)-8-(3-hydroxy-3-methyl-1E-butenyl)-xanthone 0
                      1-Hydroxy-3,7-dimethoxyxanthone 0
                      2,4-Dichloro-1,3,6-tri-O-methylnorlichexanthone 0
                      2,4-Dichloronorlichexanthone 0
                      2,4-dichlorolichexanthone 0
                      2,5,7-trichlorolichexanthone 0
                      2,5-Dichloro-1,3,6-tri-O-methylnorlichexanthone 0
                      2,5-Dichlorolichexanthone 0
                      2,5-Dichloronorlichexanthone 0
                      2-Chloro-6-O-methylnorlichexanthone 0
                      2-Chloronorlichexanthone 0
                      2-Methoxyxanthone 0
                      2-O-methylswertianin 0
                      2-[3-(4-morpholinyl)propylamino]-9-xanthenone 0
                      2-hydroxy-9-xanthenone 0
                      2-hydroxyvertixanthone 0
                      3,5-dimethoxy-1,6-dihydroxyxanthone 0
                      3-Isomangostin 0
                      3-[2-(4-chlorophenyl)-2-oxoethoxy]-1-hydroxy-9-xanthenone 0
                      4,8-dihydroxy-6-(hydroxymethyl)-9-oxo-1-xanthenecarboxylic acid methyl ester 0
                      4-Chloro-6-O-methylnorlichexanthone 0
                      4-Chlorolichexanthone 0
                      4-Chloronorlichexanthone 0
                      4-Hydroxyxanthone 0
                      5-O-demethylpaxanthonin + 0
                      5-O-methylcelebixanthone 0
                      6-Deoxy-gamma-mangostin 0
                      6-O-Methylarthothelin 0
                      7-Chloronorlichexanthone 0
                      8-Desoxygartanin 0
                      9-oxo-6-propan-2-yloxy-2-xanthenecarboxylic acid 0
                      Alloathyriol 0
                      Artonin J 0
                      Artonin K 0
                      Artonin L 0
                      Artonin T 0
                      BR-Xanthone B 0
                      Calabaxanthone 0
                      Demethylcalabaxanthone 0
                      Dulciol B 0
                      Dulciol C 0
                      Dulciol E 0
                      Dulxanthone A 0
                      Dulxanthone B 0
                      Dulxanthone C 0
                      Dulxanthone D 0
                      F390B 0
                      F390C 0
                      Garbogiol 0
                      Garciduol A 0
                      Garcimangosone C 0
                      Garcinone A 0
                      Garcinone B 0
                      Garcinone C 0
                      Gentioside 0
                      Griseoxanthone C 0
                      Mangostenol 0
                      Mangostenone B 0
                      Mangostinone 0
                      Morusignin B 0
                      Thiophanic acid 0
                      Thiophaninic acid 0
                      Thuringione 0
                      Ugaxanthone 0
                      Vinetorin 0
                      acumitin 0
                      agnestin A 0
                      agnestin B 0
                      allanxanthone C 0
                      alpha-mangostin 25
                      arthothelin 0
                      aspergillusone A 0
                      aspergillusone B 0
                      athyriol 0
                      bellidifolin + 0
                      bellidin + 0
                      beta-Mangostin 0
                      calophyllin B 0
                      celebixanthone + 0
                      chaetoxanthone C 0
                      cochinchinone A 0
                      cochinchinone B 0
                      cochinchinone G 0
                      cratoxyarborenone A 0
                      cratoxyarborenone B 0
                      cratoxyarborenone C 0
                      cratoxyarborenone E 0
                      cratoxyarborenone F 0
                      cudratricusxanthone A 11
                      decussatin 0
                      dicerandrol A 0
                      dicerandrol B 0
                      dicerandrol C 0
                      emericellin 0
                      euxanthone 0
                      gamma-mangostin 6
                      garciniaxanthone H 0
                      gartanin 0
                      gentiacaulein 0
                      gentisein 0
                      gentisin 0
                      globosuxanthone A 0
                      globosuxanthone B 0
                      globosuxanthone C 0
                      globosuxanthone D 0
                      hyperixanthone A 0
                      hyperxanthone C 0
                      irisxanthone 0
                      isoathyriol 0
                      isogentisin 0
                      isomangiferin 0
                      lancerin 0
                      lichexanthone 0
                      macluraxanthone B 0
                      macluraxanthone C 0
                      mangiferin 148
                      mepixanox 0
                      mesuaxanthone A 0
                      mesuaxanthone B 0
                      methyl 3,8-dihydroxy-6-methyl-9-oxo-9H-xanthene-1-carboxylate 0
                      methyl 8-hydroxy-6-methyl-9-oxo-9H-xanthene-1-carboxylate 0
                      microdiplodiasol 0
                      monodictysin B 0
                      nidulalin A 0
                      norathyriol + 6
                      norlichexanthone 0
                      norswertianin 0
                      norswertianolin 0
                      pancixanthone B 0
                      paxanthonin + 0
                      phomalevone A 0
                      phomalevone C 0
                      phomoxanthone A 0
                      phomoxanthone B 0
                      pinselin 0
                      prenylated and related xanthones 0
                      psorospermin 1
                      rubraxanthone 0
                      simple oxygenated xanthones 0
                      swerchirin 0
                      swertianin + 0
                      swertifrancheside 0
                      swertipunicoside 0
                      sydowinin A 0
                      sydowinin B 0
                      vadimezan 7
                      variecoxanthone C 0
                      vieillardixanthone 0
                      xanthone + 150
                      xanthone glycoside + 0
                      xanthonolignoid 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19800
    subatomic particle 19799
      composite particle 19799
        hadron 19799
          baryon 19799
            nucleon 19799
              atomic nucleus 19799
                atom 19799
                  main group element atom 19698
                    p-block element atom 19698
                      carbon group element atom 19619
                        carbon atom 19609
                          organic molecular entity 19609
                            organic group 18718
                              organic divalent group 18702
                                organodiyl group 18702
                                  carbonyl group 18651
                                    carbonyl compound 18651
                                      ketone 16957
                                        cyclic ketone 15522
                                          xanthones 174
                                            (-)-microdiplodiasolol 0
                                            (7R,8R)-AGI-B4 0
                                            (7R,8R)-alpha-diversonolic ester 0
                                            (E)-4-(3,7-Dimethyl-2,6-octadienyl)-1,3,5-trihydroxyxanthone 0
                                            1,2,5-trihydroxyxanthone 0
                                            1,3,5,6-tetrahydroxy-4,7,8-tri(3-methyl-2-butenyl)xanthone 0
                                            1,3,5-trihydroxy-2-(2',2'-dimethyl-4'-isopropenyl)cyclopentanylxanthone 0
                                            1,3,5-trihydroxyxanthone 0
                                            1,3,6-Trihydroxy-5-methoxyxanthone 0
                                            1,3,6-tri-O-methylarthothelin 0
                                            1,3,7-trihydroxy-2,4-diisoprenylxanthone 0
                                            1,3,8-trihydroxy-4-methyl-2,7-diprenylxanthone 0
                                            1,3-dihydroxy-6-methoxy-8-methyl-9-xanthenone 0
                                            1,4,5-Trihydroxy-3-prenylxanthone 0
                                            1,4,6-Trihydroxy-5-methoxy-7-prenylxanthone 0
                                            1,5,8-Trihydroxy-3-methyl-2-prenylxanthone 0
                                            1,5-Dihydroxy-3-methoxy-2-prenylxanthone 0
                                            1,6-Dihydroxy-3,7-dimethoxy-2-(3-methyl-2-butenyl)-8-(2-hydroxy-3-methyl-3-butenyl)-xanthone 0
                                            1,6-Dihydroxy-3,7-dimethoxy-2-(3-methyl-2-butenyl)-8-(2-oxo-3-methyl-3-butenyl)-xanthone 0
                                            1,6-Dihydroxy-3,8-dimethylxanthone 0
                                            1,6-Dihydroxy-3-methoxy-2-prenylxanthone 0
                                            1,7-Dihydroxy-3,6-dimethoxy-2,8-diprenylxanthone 0
                                            1,7-Dihydroxy-3-methoxy-2-prenylxanthone 0
                                            1,7-dihydroxy-4-methoxyxanthone 0
                                            1,8-Dihydroxy-3,5-dimethoxy-2-prenylxanthone 0
                                            1,8-dihydroxy-3-methoxy-6-methylxanthone 0
                                            1,8-dihydroxy-4-nitroxanthen-9-one 0
                                            1-Hydroxy-3,5-dimethoxy-2-prenylxanthone 0
                                            1-Hydroxy-3,6,7-trimethoxy-2,8-diprenylxanthone 0
                                            1-Hydroxy-3,6,7-trimethoxy-2-(2-hydroxy-3-methyl-3-butenyl)-8-(3-methyl-2-butenyl)-xanthone 0
                                            1-Hydroxy-3,6,7-trimethoxy-2-(3-methyl-2-butenyl)-8-(2-hydroxy-3-methyl-3-butenyl)-xanthone 0
                                            1-Hydroxy-3,6,7-trimethoxy-2-(3-methyl-2-butenyl)-8-(3-hydroxy-3-methyl-1E-butenyl)-xanthone 0
                                            1-Hydroxy-3,7-dimethoxyxanthone 0
                                            2,4-Dichloro-1,3,6-tri-O-methylnorlichexanthone 0
                                            2,4-Dichloronorlichexanthone 0
                                            2,4-dichlorolichexanthone 0
                                            2,5,7-trichlorolichexanthone 0
                                            2,5-Dichloro-1,3,6-tri-O-methylnorlichexanthone 0
                                            2,5-Dichlorolichexanthone 0
                                            2,5-Dichloronorlichexanthone 0
                                            2-Chloro-6-O-methylnorlichexanthone 0
                                            2-Chloronorlichexanthone 0
                                            2-Methoxyxanthone 0
                                            2-O-methylswertianin 0
                                            2-[3-(4-morpholinyl)propylamino]-9-xanthenone 0
                                            2-hydroxy-9-xanthenone 0
                                            2-hydroxyvertixanthone 0
                                            3,5-dimethoxy-1,6-dihydroxyxanthone 0
                                            3-Isomangostin 0
                                            3-[2-(4-chlorophenyl)-2-oxoethoxy]-1-hydroxy-9-xanthenone 0
                                            4,8-dihydroxy-6-(hydroxymethyl)-9-oxo-1-xanthenecarboxylic acid methyl ester 0
                                            4-Chloro-6-O-methylnorlichexanthone 0
                                            4-Chlorolichexanthone 0
                                            4-Chloronorlichexanthone 0
                                            4-Hydroxyxanthone 0
                                            5-O-demethylpaxanthonin + 0
                                            5-O-methylcelebixanthone 0
                                            6-Deoxy-gamma-mangostin 0
                                            6-O-Methylarthothelin 0
                                            7-Chloronorlichexanthone 0
                                            8-Desoxygartanin 0
                                            9-oxo-6-propan-2-yloxy-2-xanthenecarboxylic acid 0
                                            Alloathyriol 0
                                            Artonin J 0
                                            Artonin K 0
                                            Artonin L 0
                                            Artonin T 0
                                            BR-Xanthone B 0
                                            Calabaxanthone 0
                                            Demethylcalabaxanthone 0
                                            Dulciol B 0
                                            Dulciol C 0
                                            Dulciol E 0
                                            Dulxanthone A 0
                                            Dulxanthone B 0
                                            Dulxanthone C 0
                                            Dulxanthone D 0
                                            F390B 0
                                            F390C 0
                                            Garbogiol 0
                                            Garciduol A 0
                                            Garcimangosone C 0
                                            Garcinone A 0
                                            Garcinone B 0
                                            Garcinone C 0
                                            Gentioside 0
                                            Griseoxanthone C 0
                                            Mangostenol 0
                                            Mangostenone B 0
                                            Mangostinone 0
                                            Morusignin B 0
                                            Thiophanic acid 0
                                            Thiophaninic acid 0
                                            Thuringione 0
                                            Ugaxanthone 0
                                            Vinetorin 0
                                            acumitin 0
                                            agnestin A 0
                                            agnestin B 0
                                            allanxanthone C 0
                                            alpha-mangostin 25
                                            arthothelin 0
                                            aspergillusone A 0
                                            aspergillusone B 0
                                            athyriol 0
                                            bellidifolin + 0
                                            bellidin + 0
                                            beta-Mangostin 0
                                            calophyllin B 0
                                            celebixanthone + 0
                                            chaetoxanthone C 0
                                            cochinchinone A 0
                                            cochinchinone B 0
                                            cochinchinone G 0
                                            cratoxyarborenone A 0
                                            cratoxyarborenone B 0
                                            cratoxyarborenone C 0
                                            cratoxyarborenone E 0
                                            cratoxyarborenone F 0
                                            cudratricusxanthone A 11
                                            decussatin 0
                                            dicerandrol A 0
                                            dicerandrol B 0
                                            dicerandrol C 0
                                            emericellin 0
                                            euxanthone 0
                                            gamma-mangostin 6
                                            garciniaxanthone H 0
                                            gartanin 0
                                            gentiacaulein 0
                                            gentisein 0
                                            gentisin 0
                                            globosuxanthone A 0
                                            globosuxanthone B 0
                                            globosuxanthone C 0
                                            globosuxanthone D 0
                                            hyperixanthone A 0
                                            hyperxanthone C 0
                                            irisxanthone 0
                                            isoathyriol 0
                                            isogentisin 0
                                            isomangiferin 0
                                            lancerin 0
                                            lichexanthone 0
                                            macluraxanthone B 0
                                            macluraxanthone C 0
                                            mangiferin 148
                                            mepixanox 0
                                            mesuaxanthone A 0
                                            mesuaxanthone B 0
                                            methyl 3,8-dihydroxy-6-methyl-9-oxo-9H-xanthene-1-carboxylate 0
                                            methyl 8-hydroxy-6-methyl-9-oxo-9H-xanthene-1-carboxylate 0
                                            microdiplodiasol 0
                                            monodictysin B 0
                                            nidulalin A 0
                                            norathyriol + 6
                                            norlichexanthone 0
                                            norswertianin 0
                                            norswertianolin 0
                                            pancixanthone B 0
                                            paxanthonin + 0
                                            phomalevone A 0
                                            phomalevone C 0
                                            phomoxanthone A 0
                                            phomoxanthone B 0
                                            pinselin 0
                                            prenylated and related xanthones 0
                                            psorospermin 1
                                            rubraxanthone 0
                                            simple oxygenated xanthones 0
                                            swerchirin 0
                                            swertianin + 0
                                            swertifrancheside 0
                                            swertipunicoside 0
                                            sydowinin A 0
                                            sydowinin B 0
                                            vadimezan 7
                                            variecoxanthone C 0
                                            vieillardixanthone 0
                                            xanthone + 150
                                            xanthone glycoside + 0
                                            xanthonolignoid 0
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