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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:nitrohydrocarbon
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Accession:CHEBI:51129 term browser browse the term
Definition:A C-nitro compound that is a hydrocarbon in which one or more of the hydrogens has been replaced by nitro groups.
Synonyms:related_synonym: nitrohydrocarbons
 xref: PMCID:PMC3909368


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1-nitronaphthalene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2f4 cytochrome P450, family 2, subfamily f, polypeptide 4 increases abundance EXP
ISO
CYP2F4 protein results in increased abundance of 1-nitronaphthalene metabolite
CYP2F2 protein results in increased abundance of 1-nitronaphthalene metabolite
CTD PMID:15509722 NCBI chr 1:82,416,108...82,429,897
Ensembl chr 1:82,416,130...82,429,896
JBrowse link
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 increases activity ISO 1-nitronaphthalene results in increased activity of TRPA1 protein CTD PMID:21591660 NCBI chr 5:4,379,999...4,433,243
Ensembl chr 5:4,379,999...4,433,570
JBrowse link
1-nitropropane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1b ATP-binding cassette, subfamily B (MDR/TAP), member 1B increases expression EXP 1-nitropropane results in increased expression of ABCB1B mRNA CTD PMID:17070881 NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199
JBrowse link
G Acmsd aminocarboxymuconate semialdehyde decarboxylase increases expression EXP 1-nitropropane results in increased expression of ACMSD mRNA CTD PMID:17070881 NCBI chr13:39,200,486...39,244,337
Ensembl chr13:39,200,314...39,245,209
JBrowse link
G Acsl3 acyl-CoA synthetase long-chain family member 3 decreases expression EXP 1-nitropropane results in decreased expression of ACSL3 mRNA CTD PMID:17070881 NCBI chr 9:80,140,996...80,164,636
Ensembl chr 9:80,115,112...80,164,627
JBrowse link
G Aen apoptosis enhancing nuclease increases expression EXP 1-nitropropane results in increased expression of AEN mRNA CTD PMID:17070881 NCBI chr 1:132,815,094...132,824,522
Ensembl chr 1:132,815,142...132,824,523
JBrowse link
G Akr7a3 aldo-keto reductase family 7 member A3 decreases expression EXP 1-nitropropane results in decreased expression of AKR7A3 mRNA CTD PMID:17070881 NCBI chr 5:151,590,968...151,601,394
Ensembl chr 5:151,584,479...151,601,394
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 increases expression EXP 1-nitropropane results in increased expression of ALDH1A1 mRNA CTD PMID:17070881 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
JBrowse link
G Aldh1a7 aldehyde dehydrogenase family 1, subfamily A7 increases expression EXP 1-nitropropane results in increased expression of ALDH1A4 mRNA CTD PMID:17070881 NCBI chr 1:218,201,443...218,241,410
Ensembl chr 1:218,201,472...218,248,906
JBrowse link
G Apoa2 apolipoprotein A2 increases expression EXP 1-nitropropane results in increased expression of APOA2 mRNA CTD PMID:17070881 NCBI chr13:83,644,460...83,646,358
Ensembl chr13:83,644,470...83,646,355
JBrowse link
G Apoa4 apolipoprotein A4 decreases expression EXP 1-nitropropane results in decreased expression of APOA4 mRNA CTD PMID:17070881 NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469
JBrowse link
G Apoc3 apolipoprotein C3 increases expression EXP 1-nitropropane results in increased expression of APOC3 mRNA CTD PMID:17070881 NCBI chr 8:46,531,478...46,533,658
Ensembl chr 8:46,531,478...46,533,583
JBrowse link
G Atp6v1d ATPase H+ transporting V1 subunit D increases expression EXP 1-nitropropane results in increased expression of ATP6V1D mRNA CTD PMID:17070881 NCBI chr 6:97,656,725...97,672,211
Ensembl chr 6:97,656,576...97,672,303
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression EXP 1-nitropropane results in increased expression of BAX mRNA CTD PMID:17070881 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Btg2 BTG anti-proliferation factor 2 decreases expression EXP 1-nitropropane results in decreased expression of BTG2 mRNA CTD PMID:17070881 NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628
JBrowse link
G C7 complement C7 decreases expression EXP 1-nitropropane results in decreased expression of C7 mRNA CTD PMID:17070881 NCBI chr 2:54,088,116...54,165,102
Ensembl chr 2:54,088,116...54,158,535
JBrowse link
G Cblc Cbl proto-oncogene C decreases expression EXP 1-nitropropane results in decreased expression of CBLC mRNA CTD PMID:17070881 NCBI chr 1:79,439,975...79,456,755
Ensembl chr 1:79,439,977...79,456,755
JBrowse link
G Ccng1 cyclin G1 increases expression EXP 1-nitropropane results in increased expression of CCNG1 mRNA CTD PMID:17070881 NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641
JBrowse link
G Cd276 Cd276 molecule decreases expression EXP 1-nitropropane results in decreased expression of CD276 mRNA CTD PMID:17070881 NCBI chr 8:58,937,751...58,968,082
Ensembl chr 8:58,937,751...58,968,380
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A decreases expression EXP 1-nitropropane results in decreased expression of CDKN1A mRNA CTD PMID:17070881 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cpq carboxypeptidase Q decreases expression EXP 1-nitropropane results in decreased expression of CPQ mRNA CTD PMID:17070881 NCBI chr 7:64,264,025...64,830,867
Ensembl chr 7:64,264,081...64,724,546
JBrowse link
G Cryab crystallin, alpha B decreases expression EXP 1-nitropropane results in decreased expression of CRYAB mRNA CTD PMID:17070881 NCBI chr 8:51,093,441...51,099,161
Ensembl chr 8:51,093,441...51,099,157
JBrowse link
G Cyp2c13 cytochrome P450, family 2, subfamily c, polypeptide 13 decreases expression EXP 1-nitropropane results in decreased expression of CYP2C13 mRNA CTD PMID:17070881 NCBI chr 1:238,786,764...238,867,195
Ensembl chr 1:238,786,765...238,867,191
JBrowse link
G Cyp4f5 cytochrome P450, family 4, subfamily f, polypeptide 5 increases expression EXP 1-nitropropane results in increased expression of CYP4F5 mRNA CTD PMID:17070881 NCBI chr 7:11,544,040...11,558,982
Ensembl chr 7:11,544,082...11,558,978
JBrowse link
G Ddah1 dimethylarginine dimethylaminohydrolase 1 decreases expression EXP 1-nitropropane results in decreased expression of DDAH1 mRNA CTD PMID:17070881 NCBI chr 2:234,667,499...234,800,322
Ensembl chr 2:234,667,491...234,799,339
JBrowse link
G Epcam epithelial cell adhesion molecule decreases expression EXP 1-nitropropane results in decreased expression of EPCAM mRNA CTD PMID:17070881 NCBI chr 6:6,880,142...6,896,103
Ensembl chr 6:6,878,237...6,896,127
JBrowse link
G Ephx1 epoxide hydrolase 1 decreases expression EXP 1-nitropropane results in decreased expression of EPHX1 mRNA CTD PMID:17070881 NCBI chr13:92,714,315...92,744,124
Ensembl chr13:92,714,315...92,790,235
JBrowse link
G Fas Fas cell surface death receptor increases expression EXP 1-nitropropane results in increased expression of FAS mRNA CTD PMID:17070881 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Fhit fragile histidine triad diadenosine triphosphatase increases expression EXP 1-nitropropane results in increased expression of FHIT mRNA CTD PMID:17070881 NCBI chr15:13,935,029...15,442,620
Ensembl chr15:13,934,995...15,442,340
JBrowse link
G Gria3 glutamate ionotropic receptor AMPA type subunit 3 decreases expression EXP 1-nitropropane results in decreased expression of GRIA3 mRNA CTD PMID:17070881 NCBI chr  X:120,238,515...120,504,106
Ensembl chr  X:120,238,534...120,504,096
JBrowse link
G Gstm1 glutathione S-transferase mu 1 decreases expression EXP 1-nitropropane results in decreased expression of GSTM1 mRNA CTD PMID:17070881 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
JBrowse link
G Hsd17b6 hydroxysteroid (17-beta) dehydrogenase 6 increases expression EXP 1-nitropropane results in increased expression of HSD17B6 mRNA CTD PMID:17070881 NCBI chr 7:422,466...442,008
Ensembl chr 7:422,480...442,425
JBrowse link
G Il2ra interleukin 2 receptor subunit alpha decreases expression EXP 1-nitropropane results in decreased expression of IL2RA mRNA CTD PMID:17070881 NCBI chr17:66,849,974...66,898,665
Ensembl chr17:66,849,974...66,898,697
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase increases expression EXP 1-nitropropane results in increased expression of MGMT mRNA CTD PMID:17070881 NCBI chr 1:191,710,980...191,937,760
Ensembl chr 1:191,710,930...191,937,756
JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator increases expression EXP 1-nitropropane results in increased expression of NUPR1 mRNA CTD PMID:17070881 NCBI chr 1:181,213,292...181,215,327 JBrowse link
G Olr37 olfactory receptor 37 increases expression EXP 1-nitropropane results in increased expression of OLR37 mRNA CTD PMID:17070881 NCBI chr 1:154,089,219...154,090,184 JBrowse link
G Phlda3 pleckstrin homology-like domain, family A, member 3 decreases expression EXP 1-nitropropane results in decreased expression of PHLDA3 mRNA CTD PMID:17070881 NCBI chr13:47,193,250...47,196,335
Ensembl chr13:47,193,086...47,196,335
JBrowse link
G Rhobtb2 Rho-related BTB domain containing 2 increases expression EXP 1-nitropropane results in increased expression of RHOBTB2 mRNA CTD PMID:17070881 NCBI chr15:44,868,251...44,888,436
Ensembl chr15:44,870,376...44,888,651
JBrowse link
G Serpina7 serpin family A member 7 decreases expression EXP 1-nitropropane results in decreased expression of SERPINA7 mRNA CTD PMID:17070881 NCBI chr  X:102,663,242...102,722,319
Ensembl chr  X:102,663,405...102,669,040
JBrowse link
G Slc16a10 solute carrier family 16 member 10 increases expression EXP 1-nitropropane results in increased expression of SLC16A10 mRNA CTD PMID:17070881 NCBI chr20:43,454,819...43,567,839
Ensembl chr20:43,459,709...43,567,839
JBrowse link
G Spink1 serine peptidase inhibitor, Kazal type 1 increases expression EXP 1-nitropropane results in increased expression of SPINK1 mRNA CTD PMID:17070881 NCBI chr18:35,870,723...35,882,693
Ensembl chr18:35,824,550...35,882,642
JBrowse link
G Sugct succinylCoA:glutarate-CoA transferase decreases expression EXP 1-nitropropane results in decreased expression of SUGCT mRNA CTD PMID:17070881 NCBI chr17:47,376,392...48,234,362
Ensembl chr17:47,376,521...48,234,376
JBrowse link
G Sulf2 sulfatase 2 increases expression EXP 1-nitropropane results in increased expression of SULF2 mRNA CTD PMID:17070881 NCBI chr 3:154,822,079...154,904,566
Ensembl chr 3:154,822,085...154,904,415
JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 increases expression EXP 1-nitropropane results in increased expression of SULT2A1 mRNA CTD PMID:17070881 NCBI chr 1:75,451,178...75,508,142 JBrowse link
G Zmat3 zinc finger, matrin type 3 decreases expression EXP 1-nitropropane results in decreased expression of ZMAT3 mRNA CTD PMID:17070881 NCBI chr 2:115,106,050...115,136,863
Ensembl chr 2:115,106,966...115,136,863
JBrowse link
1-nitropyrene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abce1 ATP binding cassette subfamily E member 1 increases expression ISO 1-nitropyrene results in increased expression of ABCE1 mRNA CTD PMID:19041380 NCBI chr19:28,205,566...28,230,489
Ensembl chr19:28,205,555...28,230,489
JBrowse link
G Abcf1 ATP binding cassette subfamily F member 1 increases expression ISO 1-nitropyrene results in increased expression of ABCF1 mRNA CTD PMID:19428942 NCBI chr20:2,802,519...2,815,433
Ensembl chr20:2,802,488...2,815,433
JBrowse link
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 increases expression ISO 1-nitropyrene results in increased expression of ADAMTS1 mRNA CTD PMID:19041380 NCBI chr11:24,932,227...24,941,068
Ensembl chr11:24,931,761...24,941,103
JBrowse link
G Adgrg6 adhesion G protein-coupled receptor G6 increases expression ISO 1-nitropyrene results in increased expression of ADGRG6 mRNA CTD PMID:19041380 NCBI chr 1:8,812,889...8,954,239
Ensembl chr 1:8,812,904...8,954,123
JBrowse link
G Adrb2 adrenoceptor beta 2 multiple interactions ISO ADRB2 protein promotes the reaction [1-nitropyrene results in increased secretion of CXCL8 protein] CTD PMID:24904980 NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512
JBrowse link
G Aff4 AF4/FMR2 family, member 4 increases expression ISO 1-nitropyrene results in increased expression of AFF4 mRNA CTD PMID:19041380 NCBI chr10:37,498,825...37,579,751
Ensembl chr10:37,498,825...37,579,751
JBrowse link
G Aftph aftiphilin increases expression ISO 1-nitropyrene results in increased expression of AFTPH mRNA CTD PMID:19041380 NCBI chr14:94,871,429...94,925,625
Ensembl chr14:94,871,429...94,925,376
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions
affects response to substance
ISO 1-nitropyrene binds to and results in increased activity of AHR protein; [beta-Naphthoflavone binds to and results in increased activity of AHR protein] results in decreased susceptibility to [1-nitropyrene results in increased expression of TP53 protein]
AHR affects the susceptibility to 1-nitropyrene
CTD PMID:12117779 PMID:22044530 PMID:28186253 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO 1-nitropyrene results in increased phosphorylation of and results in increased activity of AKT1 protein CTD PMID:17240030 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Alcam activated leukocyte cell adhesion molecule increases expression ISO 1-nitropyrene results in increased expression of ALCAM mRNA CTD PMID:19041380 NCBI chr11:48,336,123...48,536,296
Ensembl chr11:48,336,169...48,537,954
JBrowse link
G Ang angiogenin decreases expression ISO 1-nitropyrene results in decreased expression of ANG mRNA CTD PMID:19041380 NCBI chr15:24,317,733...24,323,361 JBrowse link
G Antxr2 ANTXR cell adhesion molecule 2 increases expression ISO 1-nitropyrene results in increased expression of ANTXR2 mRNA CTD PMID:19041380 NCBI chr14:11,542,266...11,682,112
Ensembl chr14:11,541,772...11,682,094
JBrowse link
G Apcdd1 APC down-regulated 1 decreases expression ISO 1-nitropyrene results in decreased expression of APCDD1 mRNA CTD PMID:19041380 NCBI chr18:56,385,398...56,416,065
Ensembl chr18:56,385,264...56,416,070
JBrowse link
G Ar androgen receptor multiple interactions ISO 1-nitropyrene inhibits the reaction [Metribolone results in increased activity of AR protein] CTD PMID:18324785 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Arfip1 ADP-ribosylation factor interacting protein 1 increases expression ISO 1-nitropyrene results in increased expression of ARFIP1 mRNA CTD PMID:19041380 NCBI chr 2:169,843,804...169,924,136
Ensembl chr 2:169,843,801...169,923,142
JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) increases expression ISO 1-nitropyrene results in increased expression of ASNS mRNA CTD PMID:19041380 NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423
JBrowse link
G Atg7 autophagy related 7 multiple interactions
affects response to substance
increases expression
ISO 3-methyladenine inhibits the reaction [1-nitropyrene results in increased expression of ATG7 mRNA]; [Taurine co-treated with 3-methyladenine] inhibits the reaction [1-nitropyrene results in increased expression of ATG7 mRNA]; CEBPA protein inhibits the reaction [1-nitropyrene results in increased expression of ATG7 protein]; NDUFA1 protein inhibits the reaction [1-nitropyrene results in increased expression of ATG7 mRNA]; NDUFA1 protein inhibits the reaction [1-nitropyrene results in increased expression of ATG7 protein]; NDUFA2 protein inhibits the reaction [1-nitropyrene results in increased expression of ATG7 mRNA]; NDUFA2 protein inhibits the reaction [1-nitropyrene results in increased expression of ATG7 protein]
ATG7 protein affects the susceptibility to 1-nitropyrene
1-nitropyrene results in increased expression of ATG7 mRNA; 1-nitropyrene results in increased expression of ATG7 protein
ATG7 protein affects the reaction [1-nitropyrene results in increased expression of MAP1LC3B protein]; ATG7 protein affects the reaction [1-nitropyrene results in increased secretion of IL6 protein]
CTD PMID:29078374 NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593
JBrowse link
G Atp5pd ATP synthase peripheral stalk subunit d decreases expression
multiple interactions
ISO 1-nitropyrene results in decreased expression of ATP5H mRNA
[3-methyladenine co-treated with Taurine] inhibits the reaction [1-nitropyrene results in decreased expression of ATP5H mRNA]
CTD PMID:29078374 NCBI chr10:100,657,700...100,662,960
Ensembl chr10:100,657,708...100,663,479
JBrowse link
G Atp8b1 ATPase phospholipid transporting 8B1 increases expression ISO 1-nitropyrene results in increased expression of ATP8B1 mRNA CTD PMID:19041380 NCBI chr18:58,016,382...58,157,213
Ensembl chr18:58,018,268...58,157,396
JBrowse link
G Bad BCL2-associated agonist of cell death increases phosphorylation ISO 1-nitropyrene results in increased phosphorylation of BAD protein CTD PMID:17240030 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
multiple interactions
ISO 1-nitropyrene results in increased expression of BAX mRNA
TP53 affects the reaction [1-nitropyrene results in increased expression of BAX mRNA]
CTD PMID:10837373 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2a1 BCL2-related protein A1 increases expression ISO 1-nitropyrene results in increased expression of BCL2A1 mRNA CTD PMID:21540303 NCBI chr 8:89,716,914...89,724,998
Ensembl chr 8:89,716,914...89,724,998
JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression ISO 1-nitropyrene results in decreased expression of BCL2L1 protein CTD PMID:17240030 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Bid BH3 interacting domain death agonist increases expression ISO 1-nitropyrene results in increased expression of BID protein CTD PMID:17240030 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 increases expression ISO 1-nitropyrene results in increased expression of BIRC3 mRNA CTD PMID:21540303 NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802
JBrowse link
G Bmp2 bone morphogenetic protein 2 increases expression ISO 1-nitropyrene results in increased expression of BMP2 mRNA CTD PMID:21540303 NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397
JBrowse link
G Bmper BMP-binding endothelial regulator increases expression ISO 1-nitropyrene results in increased expression of BMPER mRNA CTD PMID:19041380 NCBI chr 8:21,732,225...21,977,261
Ensembl chr 8:21,732,225...21,977,256
JBrowse link
G Brca1 BRCA1, DNA repair associated decreases expression ISO 1-nitropyrene results in decreased expression of BRCA1 mRNA CTD PMID:21540303 NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304
JBrowse link
G C1qtnf2 C1q and TNF related 2 decreases expression ISO 1-nitropyrene results in decreased expression of C1QTNF2 mRNA CTD PMID:19041380 NCBI chr10:27,941,948...27,958,926
Ensembl chr10:27,941,948...27,959,185
JBrowse link
G C1rl complement C1r subcomponent like decreases expression ISO 1-nitropyrene results in decreased expression of C1RL mRNA CTD PMID:19041380 NCBI chr 4:157,394,183...157,410,771
Ensembl chr 4:157,394,200...157,410,134
JBrowse link
G Ca6 carbonic anhydrase 6 decreases expression ISO 1-nitropyrene results in decreased expression of CA6 mRNA CTD PMID:19041380 NCBI chr 5:160,658,104...160,676,644
Ensembl chr 5:160,658,105...160,676,644
JBrowse link
G Casp2 caspase 2 increases activity ISO 1-nitropyrene results in increased activity of CASP2 protein CTD PMID:21872649 NCBI chr 4:71,149,632...71,167,388
Ensembl chr 4:71,149,669...71,167,379
JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
ISO 1-nitropyrene results in increased cleavage of and results in increased activity of CASP3 protein; methyl-beta-cyclodextrin inhibits the reaction [1-nitropyrene results in increased activity of CASP3 protein] CTD PMID:17240030 PMID:21872649 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp8 caspase 8 multiple interactions ISO 1-nitropyrene results in increased cleavage of and results in increased activity of CASP8 protein CTD PMID:17240030 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Cbs cystathionine beta synthase increases expression ISO 1-nitropyrene results in increased expression of CBS mRNA CTD PMID:19041380 NCBI chr20:9,708,089...9,732,623
Ensembl chr20:9,708,090...9,732,764
JBrowse link
G Ccdc18 coiled-coil domain containing 18 increases expression ISO 1-nitropyrene results in increased expression of CCDC18 mRNA CTD PMID:19041380 NCBI chr14:1,501,749...1,607,672
Ensembl chr14:1,501,784...1,607,711
JBrowse link
G Ccl17 C-C motif chemokine ligand 17 decreases expression ISO 1-nitropyrene results in decreased expression of CCL17 mRNA CTD PMID:19428942 NCBI chr19:10,202,317...10,203,768
Ensembl chr19:10,202,128...10,203,819
JBrowse link
G Ccl19 C-C motif chemokine ligand 19 decreases expression ISO 1-nitropyrene results in decreased expression of CCL19 mRNA CTD PMID:19428942 NCBI chr 5:56,963,364...56,965,308
Ensembl chr 5:56,963,364...56,965,308
JBrowse link
G Ccl20 C-C motif chemokine ligand 20 increases expression ISO 1-nitropyrene results in increased expression of CCL20 mRNA CTD PMID:19428942 PMID:19879285 PMID:21540303 NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629
JBrowse link
G Ccl21 C-C motif chemokine ligand 21 decreases expression ISO 1-nitropyrene results in decreased expression of CCL21 mRNA CTD PMID:19428942 NCBI chr 5:56,980,557...56,981,661
Ensembl chr 5:56,980,558...56,981,686
JBrowse link
G Ccl24 C-C motif chemokine ligand 24 decreases expression ISO 1-nitropyrene results in decreased expression of CCL24 mRNA CTD PMID:19428942 NCBI chr12:21,100,835...21,104,832
Ensembl chr12:21,100,835...21,104,893
JBrowse link
G Ccl26 C-C motif chemokine ligand 26 decreases expression ISO 1-nitropyrene results in decreased expression of CCL26 mRNA CTD PMID:19428942 NCBI chr12:21,109,384...21,114,336
Ensembl chr12:21,109,421...21,114,335
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 increases expression ISO 1-nitropyrene results in increased expression of CCL5 mRNA CTD PMID:19879285 NCBI chr10:68,322,826...68,327,365
Ensembl chr10:68,322,829...68,327,377
JBrowse link
G Ccl6 C-C motif chemokine ligand 6 decreases expression ISO 1-nitropyrene results in decreased expression of CCL15 mRNA CTD PMID:19428942 NCBI chr10:68,381,179...68,385,811
Ensembl chr10:68,380,188...68,384,001
JBrowse link
G Ccn2 cellular communication network factor 2 increases expression ISO 1-nitropyrene results in increased expression of CCN2 mRNA CTD PMID:19041380 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734
JBrowse link
G Ccnd1 cyclin D1 increases expression ISO 1-nitropyrene results in increased expression of CCND1 mRNA CTD PMID:19041380 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccr4 C-C motif chemokine receptor 4 increases expression ISO 1-nitropyrene results in increased expression of CCR4 mRNA CTD PMID:19428942 NCBI chr 8:114,176,256...114,182,155
Ensembl chr 8:114,176,974...114,178,056
JBrowse link
G Ccr6 C-C motif chemokine receptor 6 decreases expression ISO 1-nitropyrene results in decreased expression of CCR6 mRNA CTD PMID:19428942 NCBI chr 1:52,474,477...52,508,301
Ensembl chr 1:52,474,168...52,498,603
JBrowse link
G Ccr7 C-C motif chemokine receptor 7 decreases expression ISO 1-nitropyrene results in decreased expression of CCR7 mRNA CTD PMID:19428942 NCBI chr10:84,098,193...84,108,309
Ensembl chr10:84,097,381...84,108,309
JBrowse link
G Ccr8 C-C motif chemokine receptor 8 decreases expression ISO 1-nitropyrene results in decreased expression of CCR8 mRNA CTD PMID:19428942 NCBI chr 8:119,826,332...119,828,292
Ensembl chr 8:119,826,568...119,827,629
JBrowse link
G Cd14 CD14 molecule decreases expression ISO 1-nitropyrene results in decreased expression of CD14 mRNA CTD PMID:19041380 NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261
JBrowse link
G Cd8b CD8b molecule decreases expression ISO 1-nitropyrene results in decreased expression of CD8B1 mRNA CTD PMID:19041380 NCBI chr 4:103,312,596...103,328,523
Ensembl chr 4:103,312,578...103,328,553
JBrowse link
G Cdh1 cadherin 1 decreases expression ISO 1-nitropyrene results in decreased expression of CDH1 mRNA CTD PMID:19041380 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
JBrowse link
G Cdh13 cadherin 13 increases expression ISO 1-nitropyrene results in increased expression of CDH13 mRNA CTD PMID:19041380 NCBI chr19:46,349,562...47,387,462
Ensembl chr19:46,349,430...47,387,459
JBrowse link
G Cdh3 cadherin 3 decreases expression ISO 1-nitropyrene results in decreased expression of CDH3 mRNA CTD PMID:19041380 NCBI chr19:34,393,596...34,444,084
Ensembl chr19:34,393,727...34,444,084
JBrowse link
G Cdk17 cyclin-dependent kinase 17 increases expression ISO 1-nitropyrene results in increased expression of CDK17 mRNA CTD PMID:19041380 NCBI chr 7:27,683,890...27,765,814
Ensembl chr 7:27,683,890...27,764,910
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
increases expression
ISO pifithrin results in decreased susceptibility to [1-nitropyrene results in increased expression of CDKN1A protein]; Tetrachlorodibenzodioxin results in decreased susceptibility to [1-nitropyrene results in increased expression of CDKN1A protein]
1-nitropyrene results in increased expression of CDKN1A mRNA; 1-nitropyrene results in increased expression of CDKN1A protein
CTD PMID:21540303 PMID:22044530 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha multiple interactions
decreases expression
ISO [Taurine co-treated with 3-methyladenine] inhibits the reaction [1-nitropyrene results in decreased expression of CEBPA mRNA]; CEBPA protein inhibits the reaction [1-nitropyrene results in increased expression of ATG7 protein] CTD PMID:29078374 NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta increases expression ISO 1-nitropyrene results in increased expression of CEBPB mRNA CTD PMID:19428942 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
JBrowse link
G Cebpd CCAAT/enhancer binding protein delta decreases expression ISO 1-nitropyrene results in decreased expression of CEBPD mRNA CTD PMID:19041380 NCBI chr11:84,764,670...84,765,808
Ensembl chr11:84,764,565...84,765,829
JBrowse link
G Cebpg CCAAT/enhancer binding protein gamma increases expression ISO 1-nitropyrene results in increased expression of CEBPG mRNA CTD PMID:19041380 NCBI chr 1:87,683,060...87,692,772
Ensembl chr 1:87,684,019...87,694,569
JBrowse link
G Cenpb centromere protein B decreases expression ISO 1-nitropyrene results in decreased expression of CENPB mRNA CTD PMID:19041380 NCBI chr 3:118,396,987...118,399,788
Ensembl chr 3:118,388,546...118,400,470
JBrowse link
G Clu clusterin decreases expression ISO 1-nitropyrene results in decreased expression of CLU mRNA CTD PMID:19041380 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315
JBrowse link
G Commd3 COMM domain containing 3 increases expression ISO 1-nitropyrene results in increased expression of COMMD3 mRNA CTD PMID:19041380 NCBI chr17:81,327,451...81,331,183
Ensembl chr17:81,327,405...81,331,177
JBrowse link
G Coro1c coronin 1C increases expression ISO 1-nitropyrene results in increased expression of CORO1C mRNA CTD PMID:19041380 NCBI chr12:42,712,960...42,785,179
Ensembl chr12:42,712,991...42,785,179
JBrowse link
G Csf2 colony stimulating factor 2 increases expression ISO 1-nitropyrene results in increased expression of CSF2 mRNA CTD PMID:21540303 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
JBrowse link
G Cth cystathionine gamma-lyase increases expression ISO 1-nitropyrene results in increased expression of CTH mRNA CTD PMID:19041380 NCBI chr 2:246,975,888...247,002,234
Ensembl chr 2:246,975,894...247,002,234
JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 increases expression ISO 1-nitropyrene results in increased expression of CXCL1 mRNA CTD PMID:19041380 PMID:19428942 PMID:19879285 NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 increases expression ISO 1-nitropyrene results in increased expression of CXCL10 mRNA CTD PMID:19428942 PMID:19879285 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
JBrowse link
G Cxcl11 C-X-C motif chemokine ligand 11 increases expression ISO 1-nitropyrene results in increased expression of CXCL11 mRNA CTD PMID:19428942 PMID:19879285 NCBI chr14:15,689,432...15,692,207
Ensembl chr14:15,689,424...15,692,271
JBrowse link
G Cxcl13 C-X-C motif chemokine ligand 13 decreases expression ISO 1-nitropyrene results in decreased expression of CXCL13 mRNA CTD PMID:19428942 NCBI chr14:13,608,894...13,613,965
Ensembl chr14:13,608,902...13,613,933
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 increases expression ISO 1-nitropyrene results in increased expression of CXCL2 mRNA CTD PMID:19041380 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 increases expression ISO 1-nitropyrene results in increased expression of CXCL1 mRNA CTD PMID:19041380 PMID:19428942 PMID:19879285 NCBI chr14:17,270,146...17,289,458
Ensembl chr14:17,270,146...17,289,511
JBrowse link
G Cxcl6 C-X-C motif chemokine ligand 6 decreases expression ISO 1-nitropyrene results in decreased expression of CXCL6 mRNA CTD PMID:19428942 NCBI chr14:17,310,089...17,312,303
Ensembl chr14:17,310,426...17,313,093
JBrowse link
G Cxcr2 C-X-C motif chemokine receptor 2 decreases expression ISO 1-nitropyrene results in decreased expression of CXCR2 mRNA CTD PMID:19428942 NCBI chr 9:75,729,493...75,735,868
Ensembl chr 9:75,729,115...75,739,425
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases degradation
multiple interactions
increases stability
increases expression
ISO
EXP
1-nitropyrene results in increased degradation of CYP1A1 protein
1-nitropyrene inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]
deguelin inhibits the reaction [1-nitropyrene results in increased stability of CYP1A1 mRNA]; triciribine inhibits the reaction [1-nitropyrene results in increased stability of CYP1A1 mRNA]
1-nitropyrene results in increased expression of CYP1A1 mRNA; 1-nitropyrene results in increased expression of CYP1A1 protein
1-nitropyrene inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA]; 1-nitropyrene inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 protein]; 1-nitropyrene inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]; CYP1A1 protein affects the susceptibility to [Tetrachlorodibenzodioxin results in decreased susceptibility to [1-nitropyrene results in increased expression of TP53 protein]]; Dithiothreitol inhibits the reaction [1-nitropyrene results in increased degradation of CYP1A1 protein]
CTD PMID:12117779 PMID:16280210 PMID:17240030 PMID:18493746 PMID:19961161 More... NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 affects response to substance
multiple interactions
ISO
EXP
CYP1A2 affects the susceptibility to 1-nitropyrene
1-nitropyrene inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]
1-nitropyrene inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]; CYP1A2 affects the reaction [1-nitropyrene results in increased mutagenesis of HPRT1 gene]
CTD PMID:10727902 PMID:18493746 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases expression
increases metabolic processing
ISO 1-nitropyrene results in increased expression of CYP1B1 mRNA
CYP1B1 protein results in increased metabolism of 1-nitropyrene
CTD PMID:11525925 PMID:12117779 PMID:21887816 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO 1-nitropyrene results in increased expression of DDIT3 mRNA CTD PMID:19041380 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 increases expression ISO 1-nitropyrene results in increased expression of DKK1 mRNA CTD PMID:19041380 NCBI chr 1:228,381,521...228,385,202
Ensembl chr 1:228,381,521...228,385,202
JBrowse link
G Dlc1 DLC1 Rho GTPase activating protein increases expression ISO 1-nitropyrene results in increased expression of DLC1 mRNA CTD PMID:19041380 NCBI chr16:55,246,716...55,671,441
Ensembl chr16:55,291,584...55,671,439
JBrowse link
G Dmtf1 cyclin D binding myb-like transcription factor 1 increases expression ISO 1-nitropyrene results in increased expression of DMTF1 mRNA CTD PMID:19041380 NCBI chr 4:24,909,937...24,950,786
Ensembl chr 4:24,910,534...24,950,967
JBrowse link
G Dner delta/notch-like EGF repeat containing increases expression ISO 1-nitropyrene results in increased expression of DNER mRNA CTD PMID:19041380 NCBI chr 9:85,586,985...85,902,820
Ensembl chr 9:85,586,987...85,902,637
JBrowse link
G Dusp10 dual specificity phosphatase 10 increases expression ISO 1-nitropyrene results in increased expression of DUSP10 mRNA CTD PMID:19041380 NCBI chr13:95,613,716...95,651,716
Ensembl chr13:95,614,292...95,651,716
JBrowse link
G Dusp6 dual specificity phosphatase 6 increases expression ISO 1-nitropyrene results in increased expression of DUSP6 mRNA CTD PMID:19041380 NCBI chr 7:34,092,848...34,097,186
Ensembl chr 7:34,092,943...34,097,185
JBrowse link
G Egr1 early growth response 1 increases expression ISO 1-nitropyrene results in increased expression of EGR1 mRNA CTD PMID:21540303 NCBI chr18:26,463,333...26,465,531
Ensembl chr18:26,462,981...26,466,766
JBrowse link
G Ehhadh enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase increases expression ISO 1-nitropyrene results in increased expression of EHHADH mRNA CTD PMID:19041380 NCBI chr11:79,241,927...79,275,173
Ensembl chr11:79,241,938...79,275,188
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 increases expression ISO 1-nitropyrene results in increased expression of EIF4EBP1 mRNA CTD PMID:19041380 NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984
JBrowse link
G Ereg epiregulin increases expression ISO 1-nitropyrene results in increased expression of EREG mRNA CTD PMID:21887816 NCBI chr14:17,027,287...17,041,062
Ensembl chr14:17,027,287...17,041,062
JBrowse link
G Esm1 endothelial cell-specific molecule 1 increases expression ISO 1-nitropyrene results in increased expression of ESM1 mRNA CTD PMID:19041380 NCBI chr 2:44,876,067...44,884,805
Ensembl chr 2:44,876,067...44,884,804
JBrowse link
G Etv5 ETS variant transcription factor 5 increases expression ISO 1-nitropyrene results in increased expression of ETV5 mRNA CTD PMID:19041380 NCBI chr11:78,608,618...78,666,221
Ensembl chr11:78,608,710...78,666,215
JBrowse link
G Evi2a ecotropic viral integration site 2A increases expression ISO 1-nitropyrene results in increased expression of EVI2A mRNA CTD PMID:19041380 NCBI chr10:64,485,760...64,489,660
Ensembl chr10:64,485,200...64,489,843
JBrowse link
G Exoc5 exocyst complex component 5 increases expression ISO 1-nitropyrene results in increased expression of EXOC5 mRNA CTD PMID:19041380 NCBI chr15:22,310,682...22,355,695
Ensembl chr15:22,308,946...22,355,335
JBrowse link
G F3 coagulation factor III, tissue factor increases expression ISO 1-nitropyrene results in increased expression of F3 mRNA CTD PMID:19041380 NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668
JBrowse link
G Fgf5 fibroblast growth factor 5 increases expression ISO 1-nitropyrene results in increased expression of FGF5 mRNA CTD PMID:19041380 NCBI chr14:11,325,334...11,346,570
Ensembl chr14:11,325,334...11,345,997
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression ISO 1-nitropyrene results in increased expression of FOS mRNA CTD PMID:21540303 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G G0s2 G0/G1switch 2 increases expression ISO 1-nitropyrene results in increased expression of G0S2 mRNA CTD PMID:19041380 NCBI chr13:104,806,351...104,807,263
Ensembl chr13:104,806,156...104,807,451
JBrowse link
G Gars glycyl-tRNA synthetase increases expression ISO 1-nitropyrene results in increased expression of GARS1 mRNA CTD PMID:19041380 NCBI chr 4:84,171,596...84,212,609
Ensembl chr 4:84,171,596...84,212,609
JBrowse link
G Gas1 growth arrest-specific 1 decreases expression ISO 1-nitropyrene results in decreased expression of GAS1 mRNA CTD PMID:19041380 NCBI chr17:4,482,014...4,485,155 JBrowse link
G Gbp2 guanylate binding protein 2 decreases expression ISO 1-nitropyrene results in decreased expression of GBP2 mRNA CTD PMID:19041380 NCBI chr 2:231,332,488...231,348,573
Ensembl chr 2:231,332,284...231,348,571
JBrowse link
G Gdap1 ganglioside-induced differentiation-associated-protein 1 increases expression ISO 1-nitropyrene results in increased expression of GDAP1 mRNA CTD PMID:19041380 NCBI chr 5:1,932,613...1,951,691
Ensembl chr 5:1,932,613...2,030,061
JBrowse link
G Glipr1 GLI pathogenesis-related 1 increases expression ISO 1-nitropyrene results in increased expression of GLIPR1 mRNA CTD PMID:19041380 NCBI chr 7:47,487,342...47,498,974
Ensembl chr 7:47,487,345...47,498,429
JBrowse link
G Golga4 golgin A4 increases expression ISO 1-nitropyrene results in increased expression of GOLGA4 mRNA CTD PMID:19041380 NCBI chr 8:118,208,200...118,285,003 JBrowse link
G Gpt2 glutamic--pyruvic transaminase 2 increases expression ISO 1-nitropyrene results in increased expression of GPT2 mRNA CTD PMID:19041380 NCBI chr19:21,526,800...21,561,314
Ensembl chr19:21,517,621...21,560,610
JBrowse link
G Grem1 gremlin 1, DAN family BMP antagonist increases expression ISO 1-nitropyrene results in increased expression of GREM1 mRNA CTD PMID:19041380 NCBI chr 3:100,512,317...100,524,001
Ensembl chr 3:100,512,313...100,524,082
JBrowse link
G Gsdmc gasdermin C decreases expression ISO 1-nitropyrene results in decreased expression of GSDMC mRNA CTD PMID:19041380 NCBI chr 7:95,594,015...95,606,106
Ensembl chr 7:95,594,015...95,611,344
JBrowse link
G Habp2 hyaluronan binding protein 2 decreases expression ISO 1-nitropyrene results in decreased expression of HABP2 mRNA CTD PMID:19041380 NCBI chr 1:255,315,870...255,350,161
Ensembl chr 1:255,315,915...255,350,160
JBrowse link
G Hbegf heparin-binding EGF-like growth factor increases expression ISO 1-nitropyrene results in increased expression of HBEGF mRNA CTD PMID:19041380 NCBI chr18:28,106,284...28,116,167
Ensembl chr18:28,105,760...28,116,441
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha increases expression ISO 1-nitropyrene results in increased expression of HIF1A mRNA CTD PMID:19041380 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Hmga2 high mobility group AT-hook 2 increases expression ISO 1-nitropyrene results in increased expression of HMGA2 mRNA CTD PMID:19041380 NCBI chr 7:55,877,145...55,998,813
Ensembl chr 7:55,880,112...55,994,784
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO 1-nitropyrene results in increased expression of HMOX1 protein CTD PMID:28633978 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 multiple interactions ISO CYP1A2 affects the reaction [1-nitropyrene results in increased mutagenesis of HPRT1 gene] CTD PMID:10727902 NCBI chr  X:132,736,175...132,768,149
Ensembl chr  X:132,736,096...132,768,154
JBrowse link
G Hras HRas proto-oncogene, GTPase affects expression
increases expression
EXP
ISO
1-nitropyrene affects the expression of HRAS mRNA
1-nitropyrene results in increased expression of HRAS mRNA
CTD PMID:9891514 PMID:11201684 PMID:11911274 NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression
multiple interactions
ISO 1-nitropyrene results in increased expression of HSPA5 protein
Dicumarol inhibits the reaction [1-nitropyrene results in increased expression of HSPA5 protein]
CTD PMID:19460413 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
JBrowse link
G Iars1 isoleucyl-tRNA synthetase 1 increases expression ISO 1-nitropyrene results in increased expression of IARS1 mRNA CTD PMID:19041380 NCBI chr17:14,940,919...14,987,277
Ensembl chr17:14,940,924...14,987,237
JBrowse link
G Icam1 intercellular adhesion molecule 1 increases expression ISO 1-nitropyrene results in increased expression of ICAM1 mRNA CTD PMID:21540303 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Ifrd1 interferon-related developmental regulator 1 increases expression ISO 1-nitropyrene results in increased expression of IFRD1 mRNA CTD PMID:19041380 NCBI chr 6:57,269,395...57,317,833
Ensembl chr 6:57,269,384...57,288,990
JBrowse link
G Il10rb interleukin 10 receptor subunit beta decreases expression ISO 1-nitropyrene results in decreased expression of IL10RB mRNA CTD PMID:19428942 NCBI chr11:30,646,494...30,668,081
Ensembl chr11:30,652,096...30,668,074
JBrowse link
G Il1a interleukin 1 alpha increases expression ISO 1-nitropyrene results in increased expression of IL1A mRNA CTD PMID:19428942 PMID:21540303 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Il1b interleukin 1 beta increases secretion ISO 1-nitropyrene results in increased secretion of IL1B protein CTD PMID:19041380 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il36rn interleukin 36 receptor antagonist decreases expression ISO 1-nitropyrene results in decreased expression of IL36RN mRNA CTD PMID:19428942 NCBI chr 3:7,044,419...7,051,016
Ensembl chr 3:7,044,406...7,051,016
JBrowse link
G Il6 interleukin 6 increases expression
increases secretion
multiple interactions
ISO 1-nitropyrene results in increased expression of IL6 mRNA
1-nitropyrene results in increased secretion of IL6 protein
3-methyladenine inhibits the reaction [1-nitropyrene results in increased secretion of IL6 protein]; [Taurine co-treated with 3-methyladenine] inhibits the reaction [1-nitropyrene results in increased secretion of IL6 protein]; ATG7 protein affects the reaction [1-nitropyrene results in increased secretion of IL6 protein]
CTD PMID:19041380 PMID:19879285 PMID:29078374 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Ina internexin neuronal intermediate filament protein, alpha increases expression ISO 1-nitropyrene results in increased expression of INA mRNA CTD PMID:19041380 NCBI chr 1:245,896,775...245,908,330
Ensembl chr 1:245,896,775...245,908,330
JBrowse link
G Inhbb inhibin subunit beta B increases expression ISO 1-nitropyrene results in increased expression of INHBB mRNA CTD PMID:19041380 NCBI chr13:30,530,860...30,536,566
Ensembl chr13:30,530,860...30,537,832
JBrowse link
G Inpp4b inositol polyphosphate-4-phosphatase type II B increases expression ISO 1-nitropyrene results in increased expression of INPP4B mRNA CTD PMID:19041380 NCBI chr19:25,920,189...26,670,085
Ensembl chr19:25,925,358...26,280,634
JBrowse link
G Ipo7 importin 7 increases expression ISO 1-nitropyrene results in increased expression of IPO7 mRNA CTD PMID:19041380 NCBI chr 1:164,062,702...164,102,938
Ensembl chr 1:164,062,702...164,102,938
JBrowse link
G Irf1 interferon regulatory factor 1 increases expression ISO 1-nitropyrene results in increased expression of IRF1 mRNA CTD PMID:21540303 NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166
JBrowse link
G Itgb4 integrin subunit beta 4 decreases expression ISO 1-nitropyrene results in decreased expression of ITGB4 mRNA CTD PMID:19041380 NCBI chr10:101,206,657...101,243,012
Ensembl chr10:101,206,665...101,243,012
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases expression ISO 1-nitropyrene results in increased expression of JUN mRNA CTD PMID:21540303 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Kctd15 potassium channel tetramerization domain containing 15 increases expression ISO 1-nitropyrene results in increased expression of KCTD15 mRNA CTD PMID:19041380 NCBI chr 1:87,258,658...87,271,979
Ensembl chr 1:87,258,658...87,273,497
JBrowse link
G Kras KRAS proto-oncogene, GTPase multiple interactions
increases mutagenesis
ISO [1-nitropyrene co-treated with KC 400] results in increased mutagenesis of KRAS gene; [1-nitropyrene co-treated with Polychlorinated Biphenyls] results in increased mutagenesis of KRAS gene; [Bleomycin co-treated with 1-nitropyrene] results in increased mutagenesis of KRAS gene
1-nitropyrene results in increased mutagenesis of KRAS gene
CTD PMID:9726818 PMID:10396879 PMID:11746253 PMID:12616606 NCBI chr 4:178,185,418...178,218,484 JBrowse link
G Krt34 keratin 34 increases expression ISO 1-nitropyrene results in increased expression of KRT34 mRNA CTD PMID:19041380 NCBI chr10:84,970,351...84,974,040
Ensembl chr10:84,970,017...84,974,040
JBrowse link
G Lcor ligand dependent nuclear receptor corepressor increases expression ISO 1-nitropyrene results in increased expression of LCOR mRNA CTD PMID:19041380 NCBI chr 1:240,298,565...240,405,627
Ensembl chr 1:240,298,563...240,402,448
JBrowse link
G Lig4 DNA ligase 4 increases expression ISO 1-nitropyrene results in increased expression of LIG4 mRNA CTD PMID:19041380 NCBI chr16:79,518,393...79,526,956
Ensembl chr16:79,518,312...79,527,040
JBrowse link
G Lman1 lectin, mannose-binding, 1 increases expression ISO 1-nitropyrene results in increased expression of LMAN1 mRNA CTD PMID:19041380 NCBI chr18:59,508,996...59,530,873
Ensembl chr18:59,508,996...59,530,851
JBrowse link
G Lrrc17 leucine rich repeat containing 17 decreases expression ISO 1-nitropyrene results in decreased expression of LRRC17 mRNA CTD PMID:19041380 NCBI chr 4:13,501,428...13,531,845
Ensembl chr 4:13,501,436...13,531,845
JBrowse link
G Lta lymphotoxin alpha decreases expression ISO 1-nitropyrene results in decreased expression of LTA mRNA CTD PMID:19428942 NCBI chr20:3,618,853...3,621,324
Ensembl chr20:3,618,853...3,620,859
JBrowse link
G Ltb lymphotoxin beta increases expression ISO 1-nitropyrene results in increased expression of LTB mRNA CTD PMID:19428942 PMID:19879285 NCBI chr20:3,627,536...3,629,381
Ensembl chr20:3,627,537...3,629,381
JBrowse link
G Lurap1l leucine rich adaptor protein 1-like increases expression ISO 1-nitropyrene results in increased expression of LURAP1L mRNA CTD PMID:19041380 NCBI chr 5:95,362,005...95,409,439
Ensembl chr 5:95,362,005...95,409,438
JBrowse link
G Mak16 MAK16 homolog increases expression ISO 1-nitropyrene results in increased expression of MAK16 mRNA CTD PMID:19041380 NCBI chr16:60,972,699...60,981,250
Ensembl chr16:60,972,697...60,983,243
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta increases expression
multiple interactions
ISO 1-nitropyrene results in increased expression of MAP1LC3B mRNA; 1-nitropyrene results in increased expression of MAP1LC3B protein
ATG7 protein affects the reaction [1-nitropyrene results in increased expression of MAP1LC3B protein]
CTD PMID:29078374 NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation ISO 1-nitropyrene results in increased phosphorylation of MAPK1 protein CTD PMID:17240030 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation ISO 1-nitropyrene results in increased phosphorylation of MAPK3 protein CTD PMID:17240030 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapk6 mitogen-activated protein kinase 6 increases expression ISO 1-nitropyrene results in increased expression of MAPK6 mRNA CTD PMID:19041380 NCBI chr 8:76,146,650...76,169,767
Ensembl chr 8:76,146,690...76,169,720
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases phosphorylation ISO 1-nitropyrene results in increased phosphorylation of MAPK8 protein CTD PMID:17240030 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Mars1 methionyl-tRNA synthetase 1 increases expression ISO 1-nitropyrene results in increased expression of MARS1 mRNA CTD PMID:19041380 NCBI chr 7:63,121,142...63,138,550
Ensembl chr 7:63,121,142...63,138,495
JBrowse link
G Mdm2 MDM2 proto-oncogene increases expression
multiple interactions
ISO 1-nitropyrene results in increased expression of MDM2 mRNA; 1-nitropyrene results in increased expression of MDM2 protein; 1-nitropyrene results in increased expression of MDM2 protein modified form
nutlin 3 results in increased susceptibility to [1-nitropyrene results in increased expression of MDM2 protein modified form]; nutlin 3 results in increased susceptibility to [1-nitropyrene results in increased expression of MDM2 protein]; Tetrachlorodibenzodioxin results in decreased susceptibility to [1-nitropyrene results in increased expression of MDM2 protein modified form]; Tetrachlorodibenzodioxin results in decreased susceptibility to [1-nitropyrene results in increased expression of MDM2 protein]; TP53 affects the reaction [1-nitropyrene results in increased expression of MDM2 mRNA]
CTD PMID:10837373 PMID:22044530 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915
JBrowse link
G Mettl7a methyltransferase like 7A decreases expression ISO 1-nitropyrene results in decreased expression of METTL7A mRNA CTD PMID:19041380 NCBI chr 7:131,452,099...131,460,154
Ensembl chr 7:131,451,641...131,460,154
JBrowse link
G Mlph melanophilin increases expression ISO 1-nitropyrene results in increased expression of MLPH mRNA CTD PMID:19041380 NCBI chr 9:91,507,410...91,542,984
Ensembl chr 9:91,507,591...91,542,983
JBrowse link
G Mob4 MOB family member 4, phocein increases expression ISO 1-nitropyrene results in increased expression of MOB4 mRNA CTD PMID:19041380 NCBI chr 9:56,617,374...56,641,336
Ensembl chr 9:56,617,368...56,641,329
JBrowse link
G Mocos molybdenum cofactor sulfurase increases expression ISO 1-nitropyrene results in increased expression of MOCOS mRNA CTD PMID:19041380 NCBI chr18:15,931,654...15,977,415
Ensembl chr18:15,931,654...15,977,187
JBrowse link
G Mospd1 motile sperm domain containing 1 increases expression ISO 1-nitropyrene results in increased expression of MOSPD1 mRNA CTD PMID:19041380 NCBI chr  X:133,100,200...133,127,960
Ensembl chr  X:133,100,422...133,127,908
JBrowse link
G Mthfd1l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like increases expression ISO 1-nitropyrene results in increased expression of MTHFD1L mRNA CTD PMID:19041380 NCBI chr 1:40,443,926...40,632,911
Ensembl chr 1:40,444,008...40,632,905
JBrowse link
G Mtmr2 myotubularin related protein 2 increases expression ISO 1-nitropyrene results in increased expression of MTMR2 mRNA CTD PMID:19041380 NCBI chr 8:10,617,993...10,670,724
Ensembl chr 8:10,617,993...10,668,172
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor increases expression ISO 1-nitropyrene results in increased expression of MYC mRNA CTD PMID:10928071 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Ndufa1 NADH:ubiquinone oxidoreductase subunit A1 decreases expression
multiple interactions
ISO 1-nitropyrene results in decreased expression of NDUFA1 mRNA
1-nitropyrene results in decreased expression of NDUFA1 mRNA; 1-nitropyrene results in decreased expression of NDUFA1 protein
[3-methyladenine co-treated with Taurine] inhibits the reaction [1-nitropyrene results in decreased expression of NDUFA1 mRNA]
[Taurine co-treated with 3-methyladenine] inhibits the reaction [1-nitropyrene results in decreased expression of NDUFA1 mRNA]; NDUFA1 protein inhibits the reaction [1-nitropyrene results in increased expression of ATG7 mRNA]; NDUFA1 protein inhibits the reaction [1-nitropyrene results in increased expression of ATG7 protein]
CTD PMID:29078374 NCBI chr  X:116,424,223...116,427,875
Ensembl chr  X:116,424,223...116,428,633
JBrowse link
G Ndufa2 NADH:ubiquinone oxidoreductase subunit A2 multiple interactions
decreases expression
ISO 3-methyladenine inhibits the reaction [1-nitropyrene results in decreased expression of NDUFA2 mRNA]; NDUFA2 protein inhibits the reaction [1-nitropyrene results in increased expression of ATG7 mRNA]; NDUFA2 protein inhibits the reaction [1-nitropyrene results in increased expression of ATG7 protein]; Taurine promotes the reaction [3-methyladenine inhibits the reaction [1-nitropyrene results in decreased expression of NDUFA2 mRNA]]
[3-methyladenine co-treated with Taurine] inhibits the reaction [1-nitropyrene results in decreased expression of NDUFA2 mRNA]
1-nitropyrene results in decreased expression of NDUFA2 mRNA; 1-nitropyrene results in decreased expression of NDUFA2 protein
CTD PMID:29078374 NCBI chr18:28,355,774...28,357,863
Ensembl chr18:28,355,774...28,358,076
JBrowse link
G Ndufc2 NADH:ubiquinone oxidoreductase subunit C2 multiple interactions
decreases expression
ISO [3-methyladenine co-treated with Taurine] inhibits the reaction [1-nitropyrene results in decreased expression of NDUFC2 mRNA] CTD PMID:29078374 NCBI chr 1:151,711,965...151,718,188
Ensembl chr 1:151,711,901...151,718,189
JBrowse link
G Ndufs4 NADH:ubiquinone oxidoreductase subunit S4 decreases expression
multiple interactions
ISO 1-nitropyrene results in decreased expression of NDUFS4 mRNA
[3-methyladenine co-treated with Taurine] inhibits the reaction [1-nitropyrene results in decreased expression of NDUFS4 mRNA]
CTD PMID:29078374 NCBI chr 2:45,951,327...46,061,829
Ensembl chr 2:45,951,313...46,061,846
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 multiple interactions ISO 1-nitropyrene results in increased expression of and affects the localization of and results in increased activity of NFE2L2 protein CTD PMID:28633978 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 increases expression
multiple interactions
increases activity
ISO 1-nitropyrene results in increased expression of NFKB1 mRNA
NFKBIA protein inhibits the reaction [1-nitropyrene results in increased activity of NFKB1 protein]
CTD PMID:12393170 PMID:21540303 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO NFKBIA protein inhibits the reaction [1-nitropyrene results in increased activity of NFKB1 protein]; NFKBIA protein inhibits the reaction [1-nitropyrene results in increased activity of RELA protein]; NFKBIA protein inhibits the reaction [1-nitropyrene results in increased expression of CXCL8 mRNA] CTD PMID:12393170 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Noc3l NOC3-like DNA replication regulator increases expression ISO 1-nitropyrene results in increased expression of NOC3L mRNA CTD PMID:19041380 NCBI chr 1:236,556,037...236,585,372
Ensembl chr 1:236,556,789...236,585,318
JBrowse link
G Nrg1 neuregulin 1 increases expression ISO 1-nitropyrene results in increased expression of NRG1 mRNA CTD PMID:19041380 NCBI chr16:59,250,658...60,303,024
Ensembl chr16:59,250,854...60,296,884
JBrowse link
G Nt5e 5' nucleotidase, ecto increases expression ISO 1-nitropyrene results in increased expression of NT5E mRNA CTD PMID:19041380 NCBI chr 8:89,271,046...89,314,918
Ensembl chr 8:89,270,696...89,314,881
JBrowse link
G Ntn3 netrin 3 decreases expression ISO 1-nitropyrene results in decreased expression of NTN3 mRNA CTD PMID:19041380 NCBI chr10:13,236,905...13,240,001
Ensembl chr10:13,236,905...13,240,001
JBrowse link
G Oas1a 2'-5' oligoadenylate synthetase 1A decreases expression ISO 1-nitropyrene results in decreased expression of OAS1 mRNA CTD PMID:19041380 NCBI chr12:35,669,798...35,680,505
Ensembl chr12:35,669,801...35,680,517
JBrowse link
G Oasl 2'-5'-oligoadenylate synthetase-like increases expression ISO 1-nitropyrene results in increased expression of OASL mRNA CTD PMID:19041380 NCBI chr12:41,682,900...41,695,641
Ensembl chr12:41,682,900...41,695,641
JBrowse link
G Osbpl6 oxysterol binding protein-like 6 increases expression ISO 1-nitropyrene results in increased expression of OSBPL6 mRNA CTD PMID:19041380 NCBI chr 3:61,343,776...61,541,170
Ensembl chr 3:61,343,809...61,537,102
JBrowse link
G Oxr1 oxidation resistance 1 increases expression ISO 1-nitropyrene results in increased expression of OXR1 mRNA CTD PMID:19041380 NCBI chr 7:72,528,782...72,965,666
Ensembl chr 7:72,528,786...72,965,666
JBrowse link
G Pcdhb8 protocadherin beta 8 decreases expression ISO 1-nitropyrene results in decreased expression of PCDHB5 mRNA CTD PMID:19041380 NCBI chr18:29,065,466...29,067,805
Ensembl chr18:29,065,466...29,067,805
JBrowse link
G Pck2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) increases expression ISO 1-nitropyrene results in increased expression of PCK2 mRNA CTD PMID:19041380 NCBI chr15:29,027,891...29,036,729
Ensembl chr15:29,027,894...29,037,283
JBrowse link
G Pdgfrb platelet derived growth factor receptor beta decreases expression ISO 1-nitropyrene results in decreased expression of PDGFRB mRNA CTD PMID:19041380 NCBI chr18:54,500,002...54,538,843
Ensembl chr18:54,499,964...54,538,843
JBrowse link
G Pdgfrl platelet-derived growth factor receptor-like decreases expression ISO 1-nitropyrene results in decreased expression of PDGFRL mRNA CTD PMID:19041380 NCBI chr16:51,347,929...51,407,850
Ensembl chr16:51,347,948...51,407,850
JBrowse link
G Pdpn podoplanin decreases expression ISO 1-nitropyrene results in decreased expression of PDPN mRNA CTD PMID:19041380 NCBI chr 5:155,601,691...155,635,656
Ensembl chr 5:155,601,691...155,635,656
JBrowse link
G Picalm phosphatidylinositol binding clathrin assembly protein increases expression ISO 1-nitropyrene results in increased expression of PICALM mRNA CTD PMID:19041380 NCBI chr 1:144,056,415...144,138,045
Ensembl chr 1:144,056,721...144,137,557
JBrowse link
G Pik3c2a phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha increases expression ISO 1-nitropyrene results in increased expression of PIK3C2A mRNA CTD PMID:19041380 NCBI chr 1:170,577,942...170,684,353
Ensembl chr 1:170,577,942...170,683,472
JBrowse link
G Pir pirin decreases expression ISO 1-nitropyrene results in decreased expression of PIR mRNA CTD PMID:19041380 NCBI chr  X:30,108,536...30,219,269
Ensembl chr  X:30,108,538...30,219,218
JBrowse link
G Plekhb1 pleckstrin homology domain containing B1 decreases expression ISO 1-nitropyrene results in decreased expression of PLEKHB1 mRNA CTD PMID:19041380 NCBI chr 1:154,998,798...155,013,094
Ensembl chr 1:154,998,800...155,016,142
JBrowse link
G Pola1 DNA polymerase alpha 1, catalytic subunit increases expression ISO 1-nitropyrene results in increased expression of POLA1 mRNA CTD PMID:19041380 NCBI chr  X:58,034,617...58,348,612
Ensembl chr  X:58,034,619...58,348,536
JBrowse link
G Polr2e RNA polymerase II, I and III subunit E decreases expression ISO 1-nitropyrene results in decreased expression of POLR2E mRNA CTD PMID:19041380 NCBI chr 7:9,666,695...9,670,638
Ensembl chr 7:9,666,716...9,670,643
JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 increases expression ISO 1-nitropyrene results in increased expression of PRKAA1 mRNA CTD PMID:19041380 NCBI chr 2:54,240,298...54,275,978
Ensembl chr 2:54,240,137...54,275,978
JBrowse link
G Prkar1a protein kinase cAMP-dependent type I regulatory subunit alpha increases expression ISO 1-nitropyrene results in increased expression of PRKAR1A mRNA CTD PMID:19041380 NCBI chr10:94,621,042...94,639,534
Ensembl chr10:94,620,039...94,639,041
JBrowse link
G Prkch protein kinase C, eta increases expression ISO 1-nitropyrene results in increased expression of PRKCH mRNA CTD PMID:19041380 NCBI chr 6:92,292,000...92,490,663
Ensembl chr 6:92,292,000...92,490,654
JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit increases expression ISO 1-nitropyrene results in increased expression of PRKDC protein CTD PMID:28633978 NCBI chr11:85,040,790...85,258,357
Ensembl chr11:85,040,792...85,257,952
JBrowse link
G Prmt3 protein arginine methyltransferase 3 increases expression ISO 1-nitropyrene results in increased expression of PRMT3 mRNA CTD PMID:19041380 NCBI chr 1:99,492,712...99,581,774
Ensembl chr 1:99,492,724...99,579,435
JBrowse link
G Psat1 phosphoserine aminotransferase 1 increases expression ISO 1-nitropyrene results in increased expression of PSAT1 mRNA CTD PMID:19041380 NCBI chr 1:213,196,709...213,218,564
Ensembl chr 1:213,196,709...213,218,682
JBrowse link
G Psmb9 proteasome 20S subunit beta 9 decreases expression ISO 1-nitropyrene results in decreased expression of PSMB9 mRNA CTD PMID:19041380 NCBI chr20:4,667,044...4,672,512
Ensembl chr20:4,666,046...4,672,512
JBrowse link
G Psmd5 proteasome 26S subunit, non-ATPase 5 increases expression ISO 1-nitropyrene results in increased expression of PSMD5 mRNA CTD PMID:19041380 NCBI chr 3:18,133,715...18,151,000
Ensembl chr 3:18,133,717...18,151,029
JBrowse link
G Psme4 proteasome activator subunit 4 increases expression ISO 1-nitropyrene results in increased expression of PSME4 mRNA CTD PMID:19041380 NCBI chr14:104,505,716...104,609,410
Ensembl chr14:104,505,716...104,609,408
JBrowse link
G Ptcd2 pentatricopeptide repeat domain 2 increases expression ISO 1-nitropyrene results in increased expression of PTCD2 mRNA CTD PMID:19041380 NCBI chr 2:30,712,276...30,739,968
Ensembl chr 2:30,712,280...30,739,942
JBrowse link
G Pthlh parathyroid hormone-like hormone increases expression ISO 1-nitropyrene results in increased expression of PTHLH mRNA CTD PMID:19041380 NCBI chr 4:180,188,792...180,199,847
Ensembl chr 4:180,188,792...180,199,847
JBrowse link
G Ptn pleiotrophin decreases expression ISO 1-nitropyrene results in decreased expression of PTN mRNA CTD PMID:19041380 NCBI chr 4:65,293,731...65,375,572
Ensembl chr 4:65,293,734...65,375,456
JBrowse link
G Ptprb protein tyrosine phosphatase, receptor type, B increases expression ISO 1-nitropyrene results in increased expression of PTPRB mRNA CTD PMID:19041380 NCBI chr 7:51,953,375...52,034,751
Ensembl chr 7:51,930,015...52,034,748
JBrowse link
G Rab20 RAB20, member RAS oncogene family decreases expression ISO 1-nitropyrene results in decreased expression of RAB20 mRNA CTD PMID:19041380 NCBI chr16:78,019,337...78,043,529
Ensembl chr16:78,019,337...78,043,529
JBrowse link
G Rab26 RAB26, member RAS oncogene family decreases expression ISO 1-nitropyrene results in decreased expression of RAB26 mRNA CTD PMID:19041380 NCBI chr10:13,553,395...13,558,063
Ensembl chr10:13,553,395...13,558,030
JBrowse link
G Rab34 RAB34, member RAS oncogene family decreases expression ISO 1-nitropyrene results in decreased expression of RAB34 mRNA CTD PMID:19041380 NCBI chr10:63,083,319...63,087,538
Ensembl chr10:63,083,338...63,087,538
JBrowse link
G Ramp1 receptor activity modifying protein 1 decreases expression ISO 1-nitropyrene results in decreased expression of RAMP1 mRNA CTD PMID:19041380 NCBI chr 9:91,765,481...91,816,152
Ensembl chr 9:91,781,285...91,816,151
JBrowse link
G Ranbp6 RAN binding protein 6 increases expression ISO 1-nitropyrene results in increased expression of RANBP6 mRNA CTD PMID:19041380 NCBI chr 1:227,572,394...227,576,915
Ensembl chr 1:227,572,105...227,576,942
JBrowse link
G Rasa2 RAS p21 protein activator 2 increases expression ISO 1-nitropyrene results in increased expression of RASA2 mRNA CTD PMID:19041380 NCBI chr 8:97,119,983...97,236,687
Ensembl chr 8:97,118,802...97,236,671
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit increases activity
multiple interactions
ISO 1-nitropyrene results in increased activity of RELA protein
NFKBIA protein inhibits the reaction [1-nitropyrene results in increased activity of RELA protein]
CTD PMID:12393170 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G RGD1306227 similar to 4833420G17Rik protein increases expression ISO 1-nitropyrene results in increased expression of C5ORF34 mRNA CTD PMID:19041380 NCBI chr 2:51,553,223...51,577,090
Ensembl chr 2:51,555,432...51,577,085
JBrowse link
G Riox2 ribosomal oxygenase 2 increases expression ISO 1-nitropyrene results in increased expression of RIOX2 mRNA CTD PMID:19041380 NCBI chr11:40,861,365...40,884,782
Ensembl chr11:40,860,774...40,884,574
JBrowse link
G Rnd3 Rho family GTPase 3 increases expression ISO 1-nitropyrene results in increased expression of RND3 mRNA CTD PMID:19041380 NCBI chr 3:35,571,929...35,589,283
Ensembl chr 3:35,571,143...35,589,327
JBrowse link
G Sacs sacsin molecular chaperone increases expression ISO 1-nitropyrene results in increased expression of SACS mRNA CTD PMID:19041380 NCBI chr15:35,285,783...35,370,335
Ensembl chr15:35,285,782...35,370,335
JBrowse link
G Scd stearoyl-CoA desaturase decreases expression
decreases response to substance
ISO 1-nitropyrene results in decreased expression of SCD1 mRNA; 1-nitropyrene results in decreased expression of SCD1 protein
SCD1 protein results in decreased susceptibility to 1-nitropyrene
CTD PMID:21872649 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
JBrowse link
G Scnn1a sodium channel epithelial 1 subunit alpha decreases expression ISO 1-nitropyrene results in decreased expression of SCNN1A mRNA CTD PMID:19041380 NCBI chr 4:158,122,962...158,146,184
Ensembl chr 4:158,122,962...158,146,181
JBrowse link
G Sectm1b secreted and transmembrane 1B decreases expression ISO 1-nitropyrene results in decreased expression of SECTM1 mRNA CTD PMID:19041380 NCBI chr10:106,325,202...106,333,769
Ensembl chr10:106,325,203...106,333,769
JBrowse link
G Sele selectin E increases expression ISO 1-nitropyrene results in increased expression of SELE mRNA CTD PMID:21540303 NCBI chr13:76,402,841...76,412,741
Ensembl chr13:76,403,304...76,412,741
JBrowse link
G Serpinb8 serpin family B member 8 increases expression ISO 1-nitropyrene results in increased expression of SERPINB8 mRNA CTD PMID:19041380 NCBI chr13:23,626,945...23,650,270
Ensembl chr13:23,626,945...23,650,835
JBrowse link
G Serpine1 serpin family E member 1 increases expression ISO 1-nitropyrene results in increased expression of SERPINE1 mRNA CTD PMID:19041380 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
JBrowse link
G Sh3kbp1 SH3 domain-containing kinase-binding protein 1 increases expression ISO 1-nitropyrene results in increased expression of SH3KBP1 mRNA CTD PMID:19041380 NCBI chr  X:34,877,862...35,223,013
Ensembl chr  X:34,877,866...35,222,747
JBrowse link
G Sh3rf1 SH3 domain containing ring finger 1 increases expression ISO 1-nitropyrene results in increased expression of SH3RF1 mRNA CTD PMID:19041380 NCBI chr16:28,735,522...28,901,690
Ensembl chr16:28,735,440...28,901,644
JBrowse link
G Slmap sarcolemma associated protein increases expression ISO 1-nitropyrene results in increased expression of SLMAP mRNA CTD PMID:19041380 NCBI chr16:1,667,205...1,785,200
Ensembl chr16:1,667,208...1,785,149
JBrowse link
G Smurf2 SMAD specific E3 ubiquitin protein ligase 2 increases expression ISO 1-nitropyrene results in increased expression of SMURF2 mRNA CTD PMID:19041380 NCBI chr10:91,761,798...91,862,485
Ensembl chr10:91,761,807...91,862,488
JBrowse link
G Snca synuclein alpha decreases expression ISO 1-nitropyrene results in decreased expression of SNCA mRNA CTD PMID:19041380 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262
JBrowse link
G Snx14 sorting nexin 14 increases expression ISO 1-nitropyrene results in increased expression of SNX14 mRNA CTD PMID:19041380 NCBI chr 8:89,283,673...89,390,597
Ensembl chr 8:89,298,114...89,390,580
JBrowse link
G Sox21 SRY-box transcription factor 21 decreases expression ISO 1-nitropyrene results in decreased expression of SOX21 mRNA CTD PMID:19041380 NCBI chr15:95,292,272...95,295,316 JBrowse link
G Spp1 secreted phosphoprotein 1 decreases expression ISO 1-nitropyrene results in decreased expression of SPP1 mRNA CTD PMID:19428942 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162
JBrowse link
G Stc2 stanniocalcin 2 increases expression ISO 1-nitropyrene results in increased expression of STC2 mRNA CTD PMID:19041380 NCBI chr10:16,251,046...16,260,815
Ensembl chr10:16,250,853...16,262,973
JBrowse link
G Tacstd2 tumor-associated calcium signal transducer 2 decreases expression ISO 1-nitropyrene results in decreased expression of TACSTD2 mRNA CTD PMID:19041380 NCBI chr 4:96,707,950...96,709,650
Ensembl chr 4:96,707,951...96,709,650
JBrowse link
G Tagln transgelin increases expression ISO 1-nitropyrene results in increased expression of TAGLN mRNA CTD PMID:19041380 NCBI chr 8:46,224,939...46,230,413
Ensembl chr 8:46,222,472...46,230,668
JBrowse link
G Tars1 threonyl-tRNA synthetase 1 increases expression ISO 1-nitropyrene results in increased expression of TARS1 mRNA CTD PMID:19041380 NCBI chr 2:60,368,251...60,387,733
Ensembl chr 2:60,367,796...60,387,717
JBrowse link
G Tax1bp1 Tax1 binding protein 1 increases expression ISO 1-nitropyrene results in increased expression of TAX1BP1 mRNA CTD PMID:19041380 NCBI chr 4:81,821,991...81,877,906
Ensembl chr 4:81,821,989...81,879,100
JBrowse link
G Thbd thrombomodulin increases expression ISO 1-nitropyrene results in increased expression of THBD mRNA CTD PMID:19041380 NCBI chr 3:135,863,366...135,867,018
Ensembl chr 3:135,862,835...135,867,193
JBrowse link
G Tlr3 toll-like receptor 3 multiple interactions ISO [Poly I-C binds to TLR3 protein] which affects the susceptibility to 1-nitropyrene CTD PMID:23458896 NCBI chr16:46,821,980...46,837,900
Ensembl chr16:46,822,039...46,836,545
JBrowse link
G Tmpo thymopoietin increases expression ISO 1-nitropyrene results in increased expression of TMPO mRNA CTD PMID:19041380 NCBI chr 7:25,642,752...25,667,756
Ensembl chr 7:25,586,725...25,667,727
JBrowse link
G Tnf tumor necrosis factor increases expression
multiple interactions
increases secretion
ISO 1-nitropyrene results in increased expression of TNF mRNA
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [1-nitropyrene results in increased expression of TNF mRNA]; MK 2206 inhibits the reaction [1-nitropyrene results in increased expression of TNF mRNA]
1-nitropyrene results in increased secretion of TNF protein
CTD PMID:19041380 PMID:19428942 PMID:19879285 PMID:21540303 PMID:28633978 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnpo1 transportin 1 increases expression ISO 1-nitropyrene results in increased expression of TNPO1 mRNA CTD PMID:19041380 NCBI chr 2:30,207,529...30,300,162
Ensembl chr 2:30,211,510...30,300,375
JBrowse link
G Top1 DNA topoisomerase I increases expression ISO 1-nitropyrene results in increased expression of TOP1 mRNA CTD PMID:19041380 NCBI chr 3:149,293,658...149,375,405
Ensembl chr 3:149,293,403...149,376,623
JBrowse link
G Top2b DNA topoisomerase II beta increases expression ISO 1-nitropyrene results in increased expression of TOP2B mRNA CTD PMID:19041380 NCBI chr15:9,051,661...9,111,220
Ensembl chr15:9,051,341...9,112,085
JBrowse link
G Tp53 tumor protein p53 increases expression
increases phosphorylation
decreases expression
affects localization
affects response to substance
affects expression
multiple interactions
ISO
EXP
1-nitropyrene results in increased expression of TP53 protein; 1-nitropyrene results in increased expression of TP53 protein modified form
1-nitropyrene results in increased phosphorylation of TRP53 protein
1-nitropyrene results in decreased expression of TRP53 mRNA
1-nitropyrene results in increased expression of TRP53 mRNA
1-nitropyrene affects the localization of TRP53 protein
TP53 affects the susceptibility to 1-nitropyrene
1-nitropyrene affects the expression of TP53 mRNA
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide results in decreased susceptibility to [Tetrachlorodibenzodioxin results in decreased susceptibility to [1-nitropyrene results in increased expression of TP53 protein]]; [beta-Naphthoflavone binds to and results in increased activity of AHR protein] results in decreased susceptibility to [1-nitropyrene results in increased expression of TP53 protein]; CYP1A1 protein affects the susceptibility to [Tetrachlorodibenzodioxin results in decreased susceptibility to [1-nitropyrene results in increased expression of TP53 protein]]; nutlin 3 results in increased susceptibility to [1-nitropyrene results in increased expression of TP53 protein modified form]; nutlin 3 results in increased susceptibility to [1-nitropyrene results in increased expression of TP53 protein]; Tetrachlorodibenzodioxin results in decreased susceptibility to [1-nitropyrene results in increased expression of TP53 protein modified form]; Tetrachlorodibenzodioxin results in decreased susceptibility to [1-nitropyrene results in increased expression of TP53 protein]; Tetrachlorodibenzodioxin results in decreased susceptibility to [nutlin 3 results in increased susceptibility to [1-nitropyrene results in increased expression of TP53 protein modified form]]; Tetrachlorodibenzodioxin results in decreased susceptibility to [nutlin 3 results in increased susceptibility to [1-nitropyrene results in increased expression of TP53 protein]]; TP53 affects the reaction [1-nitropyrene results in increased expression of BAX mRNA]; TP53 affects the reaction [1-nitropyrene results in increased expression of MDM2 mRNA]
CTD PMID:10837373 PMID:10928071 PMID:11201684 PMID:11911274 PMID:17240030 More... NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Trib3 tribbles pseudokinase 3 increases expression ISO 1-nitropyrene results in increased expression of TRIB3 mRNA CTD PMID:19041380 NCBI chr 3:140,809,634...140,815,230
Ensembl chr 3:140,809,043...140,814,497
JBrowse link
G Trim23 tripartite motif-containing 23 increases expression ISO 1-nitropyrene results in increased expression of TRIM23 mRNA CTD PMID:19041380 NCBI chr 2:35,302,405...35,335,746
Ensembl chr 2:35,302,409...35,335,743
JBrowse link
G Trpm7 transient receptor potential cation channel, subfamily M, member 7 increases expression ISO 1-nitropyrene results in increased expression of TRPM7 mRNA CTD PMID:19041380 NCBI chr 3:114,046,258...114,134,799
Ensembl chr 3:114,046,258...114,135,190
JBrowse link
G Trub1 TruB pseudouridine synthase family member 1 increases expression ISO 1-nitropyrene results in increased expression of TRUB1 mRNA CTD PMID:19041380 NCBI chr 1:256,513,418...256,554,549
Ensembl chr 1:256,515,562...256,552,814
JBrowse link
G Ubash3b ubiquitin associated and SH3 domain containing, B increases expression ISO 1-nitropyrene results in increased expression of UBASH3B mRNA CTD PMID:19041380 NCBI chr 8:41,385,419...41,532,248
Ensembl chr 8:41,388,341...41,532,201
JBrowse link
G Usp15 ubiquitin specific peptidase 15 increases expression ISO 1-nitropyrene results in increased expression of USP15 mRNA CTD PMID:19041380 NCBI chr 7:58,756,714...58,848,778
Ensembl chr 7:58,756,872...58,848,721
JBrowse link
G Vcan versican increases expression ISO 1-nitropyrene results in increased expression of VCAN mRNA CTD PMID:19041380 NCBI chr 2:20,761,718...20,860,637
Ensembl chr 2:20,761,718...20,860,637
JBrowse link
G Virma vir like m6A methyltransferase associated increases expression ISO 1-nitropyrene results in increased expression of VIRMA mRNA CTD PMID:19041380 NCBI chr 5:24,961,208...25,024,660
Ensembl chr 5:24,960,778...25,023,341
JBrowse link
G Wars1 tryptophanyl-tRNA synthetase 1 increases expression ISO 1-nitropyrene results in increased expression of WARS1 mRNA CTD PMID:19041380 NCBI chr 6:127,776,088...127,807,273
Ensembl chr 6:127,776,090...127,807,269
JBrowse link
G Wdfy3 WD repeat and FYVE domain containing 3 increases expression ISO 1-nitropyrene results in increased expression of WDFY3 mRNA CTD PMID:19041380 NCBI chr14:7,578,245...7,810,491
Ensembl chr14:7,606,628...7,810,482
JBrowse link
G Wnt2 Wnt family member 2 increases expression ISO 1-nitropyrene results in increased expression of WNT2 mRNA CTD PMID:21540303 NCBI chr 4:46,328,408...46,374,673
Ensembl chr 4:46,333,998...46,374,402
JBrowse link
G Xcr1 X-C motif chemokine receptor 1 decreases expression ISO 1-nitropyrene results in decreased expression of XCR1 mRNA CTD PMID:19428942 NCBI chr 8:123,479,454...123,516,168
Ensembl chr 8:123,479,590...123,487,226
JBrowse link
G Xpot exportin for tRNA increases expression ISO 1-nitropyrene results in increased expression of XPOT mRNA CTD PMID:19041380 NCBI chr 7:57,111,536...57,151,847
Ensembl chr 7:57,111,536...57,152,099
JBrowse link
G Zdhhc11 zinc finger, DHHC-type containing 11 increases expression ISO 1-nitropyrene results in increased expression of ZDHHC11 mRNA CTD PMID:19041380 NCBI chr 1:29,296,216...29,327,227
Ensembl chr 1:29,296,334...29,326,898
JBrowse link
G Zeb1 zinc finger E-box binding homeobox 1 increases expression ISO 1-nitropyrene results in increased expression of ZEB1 mRNA CTD PMID:19041380 NCBI chr17:51,948,948...52,116,018
Ensembl chr17:51,948,948...52,115,214
JBrowse link
G Zfp62 zinc finger protein 62 increases expression ISO 1-nitropyrene results in increased expression of ZFP62 mRNA CTD PMID:19041380 NCBI chr10:33,522,618...33,539,446
Ensembl chr10:33,500,323...33,542,013
JBrowse link
2-nitrofluorene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A increases expression EXP 2-nitrofluorene results in increased expression of ABCB1A mRNA CTD PMID:22484513 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcb1b ATP-binding cassette, subfamily B (MDR/TAP), member 1B increases expression EXP 2-nitrofluorene results in increased expression of ABCB1B mRNA CTD PMID:14600272 PMID:23052194 NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 increases expression EXP 2-nitrofluorene results in increased expression of ABCC3 mRNA CTD PMID:23052194 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595
JBrowse link
G Aco1 aconitase 1 increases expression EXP 2-nitrofluorene results in increased expression of ACO1 mRNA CTD PMID:15890375 NCBI chr 5:55,259,841...55,315,872
Ensembl chr 5:55,259,827...55,316,391
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions ISO 2-nitrofluorene binds to and results in increased activity of AHR protein CTD PMID:28186253 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Aif1 allograft inflammatory factor 1 increases expression EXP 2-nitrofluorene results in increased expression of AIF1 mRNA CTD PMID:14600272 NCBI chr20:3,646,784...3,652,670
Ensembl chr20:3,646,777...3,652,668
JBrowse link
G Akr7a3 aldo-keto reductase family 7 member A3 increases expression EXP 2-nitrofluorene results in increased expression of AKR7A3 mRNA CTD PMID:14600272 PMID:22484513 PMID:23052194 NCBI chr 5:151,590,968...151,601,394
Ensembl chr 5:151,584,479...151,601,394
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 increases expression EXP 2-nitrofluorene results in increased expression of ALDH1A1 mRNA CTD PMID:14600272 PMID:22484513 PMID:23052194 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
JBrowse link
G Anxa2 annexin A2 increases expression EXP 2-nitrofluorene results in increased expression of ANXA2 mRNA CTD PMID:14600272 NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658
JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 increases expression EXP 2-nitrofluorene results in increased expression of APEX1 mRNA CTD PMID:15890375 NCBI chr15:24,144,595...24,146,785
Ensembl chr15:24,144,362...24,146,785
JBrowse link
G Arpc1b actin related protein 2/3 complex, subunit 1B increases expression EXP 2-nitrofluorene results in increased expression of ARPC1B mRNA CTD PMID:14600272 NCBI chr12:9,482,176...9,495,772
Ensembl chr12:9,480,831...9,495,747
JBrowse link
G Atf3 activating transcription factor 3 increases expression EXP 2-nitrofluorene results in increased expression of ATF3 mRNA CTD PMID:15890375 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
JBrowse link
G Atp5mc1 ATP synthase membrane subunit c locus 1 decreases expression EXP 2-nitrofluorene results in decreased expression of ATP5MC1 mRNA CTD PMID:14600272 NCBI chr10:81,024,056...81,026,780
Ensembl chr10:81,023,925...81,027,124
Ensembl chr10:81,023,925...81,027,124
JBrowse link
G Atp6v1d ATPase H+ transporting V1 subunit D increases expression EXP 2-nitrofluorene results in increased expression of ATP6V1D mRNA CTD PMID:14600272 PMID:22484513 PMID:23052194 NCBI chr 6:97,656,725...97,672,211
Ensembl chr 6:97,656,576...97,672,303
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression EXP 2-nitrofluorene results in increased expression of BAX mRNA CTD PMID:14600272 PMID:15890375 PMID:22484513 PMID:23052194 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bhmt betaine-homocysteine S-methyltransferase decreases expression EXP 2-nitrofluorene results in decreased expression of BHMT mRNA CTD PMID:14600272 NCBI chr 2:24,859,871...24,879,449
Ensembl chr 2:24,859,873...24,879,742
JBrowse link
G Btg2 BTG anti-proliferation factor 2 increases expression EXP 2-nitrofluorene results in increased expression of BTG2 mRNA CTD PMID:14600272 PMID:15890375 PMID:23052194 NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628
JBrowse link
G Ccdc86 coiled-coil domain containing 86 increases expression EXP 2-nitrofluorene results in increased expression of CCDC86 mRNA CTD PMID:22484513 NCBI chr 1:207,590,946...207,596,527
Ensembl chr 1:207,590,168...207,596,544
JBrowse link
G Ccnb1 cyclin B1 increases expression EXP 2-nitrofluorene results in increased expression of CCNB1 mRNA CTD PMID:15890375 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
JBrowse link
G Ccnd1 cyclin D1 increases expression EXP 2-nitrofluorene results in increased expression of CCND1 mRNA CTD PMID:14600272 PMID:15890375 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccng1 cyclin G1 increases expression EXP 2-nitrofluorene results in increased expression of CCNG1 mRNA CTD PMID:14600272 PMID:15890375 PMID:22484513 PMID:23052194 NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641
JBrowse link
G Cct3 chaperonin containing TCP1 subunit 3 increases expression EXP 2-nitrofluorene results in increased expression of CCT3 mRNA CTD PMID:15890375 NCBI chr 2:173,765,792...173,790,353
Ensembl chr 2:173,765,698...173,790,757
JBrowse link
G Cd1d1 CD1d1 molecule decreases expression EXP 2-nitrofluorene results in decreased expression of CD1D1 mRNA CTD PMID:22484513 NCBI chr 2:172,423,582...172,427,089
Ensembl chr 2:172,423,582...172,427,089
JBrowse link
G Cd74 CD74 molecule increases expression EXP 2-nitrofluorene results in increased expression of CD74 mRNA CTD PMID:14600272 NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003
JBrowse link
G Cdc20 cell division cycle 20 decreases expression EXP 2-nitrofluorene results in decreased expression of CDC20 mRNA CTD PMID:15890375 NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512
JBrowse link
G Cdk1 cyclin-dependent kinase 1 increases expression EXP 2-nitrofluorene results in increased expression of CDK1 mRNA CTD PMID:15890375 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
JBrowse link
G Cdk16 cyclin-dependent kinase 16 increases expression EXP 2-nitrofluorene results in increased expression of CDK16 mRNA CTD PMID:15890375 NCBI chr  X:1,492,814...1,504,309
Ensembl chr  X:1,492,814...1,504,148
JBrowse link
G Cdk4 cyclin-dependent kinase 4 increases expression EXP 2-nitrofluorene results in increased expression of CDK4 mRNA CTD PMID:15890375 NCBI chr 7:62,885,647...62,889,562
Ensembl chr 7:62,883,105...62,942,403
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression EXP 2-nitrofluorene results in increased expression of CDKN1A mRNA CTD PMID:14600272 PMID:15890375 PMID:22484513 PMID:23052194 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Ces2c carboxylesterase 2C increases expression EXP 2-nitrofluorene results in increased expression of CES2C mRNA CTD PMID:23052194 NCBI chr 1:260,391,190...260,398,757
Ensembl chr 1:260,388,902...260,398,790
JBrowse link
G Ces2h carboxylesterase 2H increases expression EXP 2-nitrofluorene results in increased expression of CES2 mRNA CTD PMID:14600272 PMID:22484513 NCBI chr19:32,974,242...32,988,842
Ensembl chr19:32,974,242...32,988,830
JBrowse link
G Cgref1 cell growth regulator with EF hand domain 1 increases expression EXP 2-nitrofluorene results in increased expression of CGREF1 mRNA CTD PMID:14600272 PMID:15890375 PMID:23052194 NCBI chr 6:25,431,846...25,443,853
Ensembl chr 6:25,431,799...25,443,852
JBrowse link
G Cgrrf1 cell growth regulator with ring finger domain 1 increases expression EXP 2-nitrofluorene results in increased expression of CGRRF1 mRNA CTD PMID:15890375 NCBI chr15:20,088,564...20,109,042
Ensembl chr15:20,088,571...20,109,037
JBrowse link
G Cr1l complement C3b/C4b receptor 1 like increases expression EXP 2-nitrofluorene results in increased expression of CR1L mRNA CTD PMID:15890375 PMID:22484513 NCBI chr13:106,606,952...106,660,442
Ensembl chr13:106,574,858...106,660,445
JBrowse link
G Cryab crystallin, alpha B increases expression EXP 2-nitrofluorene results in increased expression of CRYAB mRNA CTD PMID:14600272 NCBI chr 8:51,093,441...51,099,161
Ensembl chr 8:51,093,441...51,099,157
JBrowse link
G Cstb cystatin B increases expression EXP 2-nitrofluorene results in increased expression of CSTB mRNA CTD PMID:15890375 NCBI chr20:10,245,462...10,247,505
Ensembl chr20:10,245,462...10,247,526
JBrowse link
G Ctsd cathepsin D increases expression EXP 2-nitrofluorene results in increased expression of CTSD mRNA CTD PMID:15890375 NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488
JBrowse link
G Ctss cathepsin S increases expression EXP 2-nitrofluorene results in increased expression of CTSS mRNA CTD PMID:14600272 NCBI chr 2:183,089,192...183,114,483
Ensembl chr 2:183,086,437...183,114,483
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 increases expression EXP 2-nitrofluorene results in increased expression of CXCL10 mRNA CTD PMID:14600272 PMID:15890375 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 affects expression EXP 2-nitrofluorene affects the expression of CXCL3 mRNA CTD PMID:22484513 NCBI chr14:17,270,146...17,289,458
Ensembl chr14:17,270,146...17,289,511
JBrowse link
G Cyb5r3 cytochrome b5 reductase 3 decreases expression EXP 2-nitrofluorene results in decreased expression of CYB5R3 mRNA CTD PMID:14600272 NCBI chr 7:114,306,686...114,324,247
Ensembl chr 7:114,306,685...114,324,298
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression EXP 2-nitrofluorene results in increased expression of CYP1A1 mRNA CTD PMID:23052194 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp2c12 cytochrome P450, family 2, subfamily c, polypeptide 12 decreases expression
increases expression
EXP 2-nitrofluorene results in decreased expression of CYP2C12 mRNA
2-nitrofluorene results in increased expression of CYP2C12 mRNA
CTD PMID:23052194 NCBI chr 1:238,699,859...238,757,011
Ensembl chr 1:238,699,854...238,757,019
JBrowse link
G Dcn decorin increases expression EXP 2-nitrofluorene results in increased expression of DCN mRNA CTD PMID:14600272 NCBI chr 7:32,281,252...32,321,291
Ensembl chr 7:32,281,252...32,321,270
JBrowse link
G Ddah1 dimethylarginine dimethylaminohydrolase 1 increases expression EXP 2-nitrofluorene results in increased expression of DDAH1 mRNA CTD PMID:15890375 NCBI chr 2:234,667,499...234,800,322
Ensembl chr 2:234,667,491...234,799,339
JBrowse link
G Ddx21 DExD-box helicase 21 increases expression EXP 2-nitrofluorene results in increased expression of DDX21 mRNA CTD PMID:15890375 NCBI chr20:30,534,319...30,554,513
Ensembl chr20:30,534,319...30,554,543
JBrowse link
G Dkc1 dyskerin pseudouridine synthase 1 decreases expression EXP 2-nitrofluorene results in decreased expression of DKC1 mRNA CTD PMID:15890375
G Dmbt1 deleted in malignant brain tumors 1 increases expression EXP 2-nitrofluorene results in increased expression of DMBT1 mRNA CTD PMID:23052194 NCBI chr 1:185,617,469...185,696,476 JBrowse link
G Dpyd dihydropyrimidine dehydrogenase decreases expression EXP 2-nitrofluorene results in decreased expression of DPYD mRNA CTD PMID:15890375 NCBI chr 2:206,609,043...207,474,982
Ensembl chr 2:206,609,122...207,474,982
JBrowse link
G Dus1l dihydrouridine synthase 1-like increases expression EXP 2-nitrofluorene results in increased expression of DUS1L mRNA CTD PMID:22484513 NCBI chr10:106,055,519...106,062,656
Ensembl chr10:106,055,519...106,062,781
JBrowse link
G Dusp6 dual specificity phosphatase 6 decreases expression EXP 2-nitrofluorene results in decreased expression of DUSP6 mRNA CTD PMID:15890375 NCBI chr 7:34,092,848...34,097,186
Ensembl chr 7:34,092,943...34,097,185
JBrowse link
G Dut deoxyuridine triphosphatase increases expression EXP 2-nitrofluorene results in increased expression of DUT mRNA CTD PMID:15890375 NCBI chr 3:112,498,864...112,509,994
Ensembl chr 3:112,498,982...112,510,771
JBrowse link
G Eef1g eukaryotic translation elongation factor 1 gamma increases expression EXP 2-nitrofluorene results in increased expression of EEF1G mRNA CTD PMID:15890375 NCBI chr 1:205,860,713...205,871,319
Ensembl chr 1:205,860,698...205,872,382
JBrowse link
G Eef2 eukaryotic translation elongation factor 2 increases expression EXP 2-nitrofluorene results in increased expression of EEF2 mRNA CTD PMID:15890375 NCBI chr 7:8,533,248...8,538,518
Ensembl chr 7:8,533,116...8,559,183
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 increases expression EXP 2-nitrofluorene results in increased expression of EIF4EBP1 mRNA CTD PMID:15890375 NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984
JBrowse link
G Ephx1 epoxide hydrolase 1 increases expression EXP 2-nitrofluorene results in increased expression of EPHX1 mRNA CTD PMID:14600272 PMID:15890375 PMID:22484513 NCBI chr13:92,714,315...92,744,124
Ensembl chr13:92,714,315...92,790,235
JBrowse link
G Fam162a family with sequence similarity 162, member A increases expression EXP 2-nitrofluorene results in increased expression of FAM162A mRNA CTD PMID:15890375 NCBI chr11:64,680,937...64,711,239
Ensembl chr11:64,680,323...64,711,239
JBrowse link
G Fcgr2a Fc fragment of IgG receptor IIa increases expression EXP 2-nitrofluorene results in increased expression of FCGR3 mRNA CTD PMID:14600272 NCBI chr13:83,280,782...83,297,535
Ensembl chr13:83,280,784...83,295,967
JBrowse link
G Fkbp4 FKBP prolyl isomerase 4 increases expression EXP 2-nitrofluorene results in increased expression of FKBP4 mRNA CTD PMID:15890375 NCBI chr 4:161,703,379...161,711,833
Ensembl chr 4:161,703,379...161,711,833
JBrowse link
G Fn1 fibronectin 1 decreases expression EXP 2-nitrofluorene results in decreased expression of FN1 mRNA CTD PMID:15890375 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression EXP 2-nitrofluorene results in increased expression of GADD45A mRNA CTD PMID:15890375 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
JBrowse link
G Gas6 growth arrest specific 6 decreases expression
increases expression
EXP 2-nitrofluorene results in decreased expression of GAS6 mRNA
2-nitrofluorene results in increased expression of GAS6 mRNA
CTD PMID:14600272 PMID:15890375 PMID:23052194 NCBI chr16:76,045,430...76,075,904
Ensembl chr16:76,045,426...76,075,904
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression EXP 2-nitrofluorene results in increased expression of GCLC mRNA CTD PMID:14600272 PMID:15890375 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Gdf15 growth differentiation factor 15 increases expression EXP 2-nitrofluorene results in increased expression of GDF15 mRNA CTD PMID:14600272 PMID:15890375 PMID:23052194 NCBI chr16:18,805,312...18,807,893
Ensembl chr16:18,805,239...18,808,055
JBrowse link
G Gls2 glutaminase 2 decreases expression EXP 2-nitrofluorene results in decreased expression of GLS2 mRNA CTD PMID:14600272 NCBI chr 7:617,252...633,424
Ensembl chr 7:617,288...633,426
JBrowse link
G Gnmt glycine N-methyltransferase decreases expression EXP 2-nitrofluorene results in decreased expression of GNMT mRNA CTD PMID:14600272 NCBI chr 9:14,254,675...14,258,028
Ensembl chr 9:14,254,675...14,258,434
JBrowse link
G Gpr108 G protein-coupled receptor 108 decreases expression EXP 2-nitrofluorene results in decreased expression of GPR108 mRNA CTD PMID:22484513 NCBI chr 9:2,120,740...2,131,771
Ensembl chr 9:2,120,744...2,132,572
JBrowse link
G Gria3 glutamate ionotropic receptor AMPA type subunit 3 increases expression EXP 2-nitrofluorene results in increased expression of GRIA3 mRNA CTD PMID:22484513 NCBI chr  X:120,238,515...120,504,106
Ensembl chr  X:120,238,534...120,504,096
JBrowse link
G Grpel1 GrpE-like 1, mitochondrial increases expression EXP 2-nitrofluorene results in increased expression of GRPEL1 mRNA CTD PMID:14600272 PMID:15890375 NCBI chr14:74,292,023...74,298,243
Ensembl chr14:74,292,023...74,298,200
JBrowse link
G Gsr glutathione-disulfide reductase increases expression EXP 2-nitrofluorene results in increased expression of GSR mRNA CTD PMID:14600272 PMID:15890375 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Gss glutathione synthetase increases expression EXP 2-nitrofluorene results in increased expression of GSS mRNA CTD PMID:15890375 NCBI chr 3:144,047,849...144,078,197
Ensembl chr 3:144,047,850...144,078,198
JBrowse link
G Gsta2 glutathione S-transferase alpha 2 increases expression EXP 2-nitrofluorene results in increased expression of GSTA2 mRNA CTD PMID:15890375 NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798
JBrowse link
G Gsta5 glutathione S-transferase alpha 5 increases expression EXP 2-nitrofluorene results in increased expression of GSTA5 mRNA CTD PMID:14600272 NCBI chr 8:79,105,561...79,117,472
Ensembl chr 8:79,105,661...79,117,472
JBrowse link
G Gstp1 glutathione S-transferase pi 1 increases expression EXP 2-nitrofluorene results in increased expression of GSTP1 mRNA CTD PMID:23052194 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link
G H2ax H2A.X variant histone increases expression EXP 2-nitrofluorene results in increased expression of H2AX mRNA CTD PMID:15890375 NCBI chr 8:44,671,927...44,673,257
Ensembl chr 8:44,671,786...44,673,239
JBrowse link
G H2az1 H2A.Z variant histone 1 increases expression EXP 2-nitrofluorene results in increased expression of H2AZ1 mRNA CTD PMID:15890375 NCBI chr 2:226,355,769...226,357,878
Ensembl chr 2:226,355,708...226,358,485
JBrowse link
G Hdc histidine decarboxylase increases expression EXP 2-nitrofluorene results in increased expression of HDC mRNA CTD PMID:15890375 NCBI chr 3:113,847,256...113,865,334
Ensembl chr 3:113,847,260...113,865,341
JBrowse link
G Hectd1 HECT domain E3 ubiquitin protein ligase 1 increases expression EXP 2-nitrofluorene results in increased expression of HECTD1 mRNA CTD PMID:22484513 NCBI chr 6:69,181,429...69,267,803
Ensembl chr 6:69,181,436...69,268,053
JBrowse link
G Hmgb2 high mobility group box 2 increases expression EXP 2-nitrofluorene results in increased expression of HMGB2 mRNA CTD PMID:15890375 NCBI chr16:32,710,651...32,713,230
Ensembl chr16:32,710,658...32,713,140
JBrowse link
G Hmox1 heme oxygenase 1 increases expression EXP 2-nitrofluorene results in increased expression of HMOX1 mRNA CTD PMID:15890375 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hsf1 heat shock transcription factor 1 increases expression EXP 2-nitrofluorene results in increased expression of HSF1 mRNA CTD PMID:15890375 NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011
JBrowse link
G Hspa9 heat shock protein family A (Hsp70) member 9 increases expression EXP 2-nitrofluorene results in increased expression of HSPA9 mRNA CTD PMID:15890375 NCBI chr18:26,536,131...26,554,294
Ensembl chr18:26,535,798...26,554,292
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 increases expression EXP 2-nitrofluorene results in increased expression of HSPB1 mRNA CTD PMID:15890375 NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743
JBrowse link
G Hspe1 heat shock protein family E (Hsp10) member 1 increases expression EXP 2-nitrofluorene results in increased expression of HSPE1 mRNA CTD PMID:15890375 NCBI chr 9:56,589,912...56,593,000
Ensembl chr 9:56,589,789...56,593,089
JBrowse link
G Hsph1 heat shock protein family H (Hsp110) member 1 increases expression EXP 2-nitrofluorene results in increased expression of HSPH1 mRNA CTD PMID:15890375 NCBI chr12:5,390,916...5,410,224
Ensembl chr12:5,390,922...5,410,224
JBrowse link
G Ide insulin degrading enzyme increases expression EXP 2-nitrofluorene results in increased expression of IDE mRNA CTD PMID:15890375 NCBI chr 1:235,002,984...235,102,448
Ensembl chr 1:234,995,351...235,102,440
JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 increases expression EXP 2-nitrofluorene results in increased expression of IGFBP1 mRNA CTD PMID:15890375 NCBI chr14:82,047,415...82,052,482
Ensembl chr14:82,047,415...82,052,482
JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 decreases expression EXP 2-nitrofluorene results in decreased expression of IGFBP3 mRNA CTD PMID:15890375 NCBI chr14:82,056,347...82,064,083
Ensembl chr14:82,056,347...82,064,083
JBrowse link
G Irf1 interferon regulatory factor 1 increases expression EXP 2-nitrofluorene results in increased expression of IRF1 mRNA CTD PMID:14600272 NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166
JBrowse link
G Lama5 laminin subunit alpha 5 increases expression EXP 2-nitrofluorene results in increased expression of LAMA5 mRNA CTD PMID:22484513 NCBI chr 3:167,270,296...167,318,370
Ensembl chr 3:167,270,296...167,318,451
JBrowse link
G Lgals3 galectin 3 increases expression EXP 2-nitrofluorene results in increased expression of LGALS3 mRNA CTD PMID:15890375 NCBI chr15:20,620,083...20,632,019
Ensembl chr15:20,607,692...20,632,025
JBrowse link
G Map2k6 mitogen-activated protein kinase kinase 6 decreases expression EXP 2-nitrofluorene results in decreased expression of MAP2K6 mRNA CTD PMID:22484513 NCBI chr10:95,373,304...95,490,406
Ensembl chr10:95,373,204...95,488,293
JBrowse link
G Mat1a methionine adenosyltransferase 1A decreases expression EXP 2-nitrofluorene results in decreased expression of MAT1A mRNA CTD PMID:14600272 NCBI chr16:16,983,084...17,001,284
Ensembl chr16:16,983,022...17,001,274
JBrowse link
G Mcm6 minichromosome maintenance complex component 6 increases expression EXP 2-nitrofluorene results in increased expression of MCM6 mRNA CTD PMID:15890375 NCBI chr13:39,826,745...39,851,937
Ensembl chr13:39,826,763...39,851,960
JBrowse link
G Mdm2 MDM2 proto-oncogene increases expression EXP 2-nitrofluorene results in increased expression of MDM2 mRNA CTD PMID:14600272 PMID:15890375 PMID:22484513 PMID:23052194 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase increases expression EXP 2-nitrofluorene results in increased expression of MGMT mRNA CTD PMID:14600272 PMID:15890375 PMID:22484513 PMID:23052194 NCBI chr 1:191,710,980...191,937,760
Ensembl chr 1:191,710,930...191,937,756
JBrowse link
G Mt1 metallothionein 1 decreases expression EXP 2-nitrofluorene results in decreased expression of MT1A mRNA CTD PMID:14600272 PMID:15890375 NCBI chr19:10,826,032...10,827,048 JBrowse link
G Mt2A metallothionein 2A decreases expression EXP 2-nitrofluorene results in decreased expression of MT2 mRNA; 2-nitrofluorene results in decreased expression of MT2A mRNA CTD PMID:14600272 PMID:15890375 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor increases expression EXP 2-nitrofluorene results in increased expression of MYC mRNA CTD PMID:15890375 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Naglt1 Na+ dependent glucose transporter 1 affects expression EXP 2-nitrofluorene affects the expression of NAGLT1 mRNA CTD PMID:22484513 NCBI chr20:43,411,550...43,423,873
Ensembl chr20:43,394,843...43,423,873
JBrowse link
G Nap1l1 nucleosome assembly protein 1-like 1 increases expression EXP 2-nitrofluorene results in increased expression of NAP1L1 mRNA CTD PMID:15890375 NCBI chr 7:46,933,278...46,957,853
Ensembl chr 7:46,933,356...46,956,593
JBrowse link
G Nhej1 nonhomologous end-joining factor 1 increases expression EXP 2-nitrofluorene results in increased expression of NHEJ1 mRNA CTD PMID:22484513 NCBI chr 9:76,526,322...76,622,488
Ensembl chr 9:76,526,324...76,622,444
JBrowse link
G Npm1 nucleophosmin 1 increases expression EXP 2-nitrofluorene results in increased expression of NPM1 mRNA CTD PMID:15890375 NCBI chr10:17,741,512...17,751,626
Ensembl chr10:17,739,941...17,751,645
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression EXP 2-nitrofluorene results in increased expression of NQO1 mRNA CTD PMID:14600272 PMID:15890375 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Nrg1 neuregulin 1 increases expression EXP 2-nitrofluorene results in increased expression of NRG1 mRNA CTD PMID:14600272 PMID:15890375 PMID:22484513 PMID:23052194 NCBI chr16:59,250,658...60,303,024
Ensembl chr16:59,250,854...60,296,884
JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator decreases expression EXP 2-nitrofluorene results in decreased expression of NUPR1 mRNA CTD PMID:15890375 PMID:23052194 NCBI chr 1:181,213,292...181,215,327 JBrowse link
G Oat ornithine aminotransferase decreases expression EXP 2-nitrofluorene results in decreased expression of OAT mRNA CTD PMID:14600272 PMID:22484513 NCBI chr 1:187,347,862...187,367,644
Ensembl chr 1:187,347,865...187,367,682
JBrowse link
G Obp3 alpha-2u globulin PGCL4 decreases expression EXP 2-nitrofluorene results in decreased expression of OBP3 mRNA CTD PMID:15890375 NCBI chr 5:74,842,316...74,845,858
Ensembl chr 5:74,842,316...74,845,757
JBrowse link
G Odc1 ornithine decarboxylase 1 increases expression EXP 2-nitrofluorene results in increased expression of ODC1 mRNA CTD PMID:15890375 NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440
JBrowse link
G Pcna proliferating cell nuclear antigen increases expression EXP 2-nitrofluorene results in increased expression of PCNA mRNA CTD PMID:15890375 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
JBrowse link
G Pdcd4 programmed cell death 4 decreases expression ISO 2-nitrofluorene results in decreased expression of PDCD4 mRNA CTD PMID:21873647 NCBI chr 1:252,921,342...252,944,278
Ensembl chr 1:252,921,392...252,944,275
JBrowse link
G Phgdh phosphoglycerate dehydrogenase decreases expression EXP 2-nitrofluorene results in decreased expression of PHGDH mRNA CTD PMID:15890375 NCBI chr 2:185,906,964...185,936,160
Ensembl chr 2:185,906,966...185,935,944
JBrowse link
G Phlda3 pleckstrin homology-like domain, family A, member 3 increases expression EXP 2-nitrofluorene results in increased expression of PHLDA3 mRNA CTD PMID:22484513 PMID:23052194 NCBI chr13:47,193,250...47,196,335
Ensembl chr13:47,193,086...47,196,335
JBrowse link
G Pmm1 phosphomannomutase 1 increases expression EXP 2-nitrofluorene results in increased expression of PMM1 mRNA CTD PMID:22484513 NCBI chr 7:113,466,632...113,477,004
Ensembl chr 7:113,466,632...113,477,022
JBrowse link
G Psma1 proteasome 20S subunit alpha 1 increases expression EXP 2-nitrofluorene results in increased expression of PSMA1 mRNA CTD PMID:15890375 NCBI chr 1:168,442,421...168,453,440
Ensembl chr 1:168,440,936...168,453,472
JBrowse link
G Psma2 proteasome 20S subunit alpha 2 increases expression EXP 2-nitrofluorene results in increased expression of PSMA2 mRNA CTD PMID:15890375 NCBI chr17:50,554,536...50,564,923
Ensembl chr17:50,551,924...50,564,938
JBrowse link
G Psma4 proteasome 20S subunit alpha 4 increases expression EXP 2-nitrofluorene results in increased expression of PSMA4 mRNA CTD PMID:15890375 NCBI chr 8:55,340,431...55,347,893
Ensembl chr 8:55,340,386...55,347,890
JBrowse link
G Psma5 proteasome 20S subunit alpha 5 increases expression EXP 2-nitrofluorene results in increased expression of PSMA5 mRNA CTD PMID:15890375 NCBI chr 2:195,896,369...195,919,733
Ensembl chr 2:195,896,365...195,919,731
JBrowse link
G Psma7 proteasome 20S subunit alpha 7 increases expression EXP 2-nitrofluorene results in increased expression of PSMA7 mRNA CTD PMID:15890375 NCBI chr 3:167,137,279...167,143,626
Ensembl chr 3:167,137,263...167,143,672
JBrowse link
G Psmb1 proteasome 20S subunit beta 1 increases expression EXP 2-nitrofluorene results in increased expression of PSMB1 mRNA CTD PMID:15890375 NCBI chr 1:56,442,432...56,463,544
Ensembl chr 1:56,420,618...56,463,560
JBrowse link
G Psmb3 proteasome 20S subunit beta 3 increases expression EXP 2-nitrofluorene results in increased expression of PSMB3 mRNA CTD PMID:15890375 NCBI chr10:82,697,425...82,704,521
Ensembl chr10:82,697,425...82,704,521
JBrowse link
G Psmb4 proteasome 20S subunit beta 4 increases expression EXP 2-nitrofluorene results in increased expression of PSMB4 mRNA CTD PMID:15890375 NCBI chr 2:182,442,757...182,445,532
Ensembl chr 2:182,442,756...182,445,746
JBrowse link
G Psmb5 proteasome 20S subunit beta 5 increases expression EXP 2-nitrofluorene results in increased expression of PSMB5 mRNA CTD PMID:15890375 NCBI chr15:28,072,772...28,077,367
Ensembl chr15:28,072,781...28,077,440
JBrowse link
G Psmb8 proteasome 20S subunit beta 8 increases expression EXP 2-nitrofluorene results in increased expression of PSMB8 mRNA CTD PMID:14600272 NCBI chr20:4,652,159...4,655,122
Ensembl chr20:4,652,159...4,655,283
JBrowse link
G Psmb9 proteasome 20S subunit beta 9 increases expression EXP 2-nitrofluorene results in increased expression of PSMB9 mRNA CTD PMID:14600272 NCBI chr20:4,667,044...4,672,512
Ensembl chr20:4,666,046...4,672,512
JBrowse link
G Psmc1 proteasome 26S subunit, ATPase 1 increases expression EXP 2-nitrofluorene results in increased expression of PSMC1 mRNA CTD PMID:15890375 NCBI chr 6:119,392,833...119,405,233
Ensembl chr 6:119,392,855...119,410,123
JBrowse link
G Psmc2 proteasome 26S subunit, ATPase 2 increases expression EXP 2-nitrofluorene results in increased expression of PSMC2 mRNA CTD PMID:15890375 NCBI chr 4:13,255,851...13,270,102
Ensembl chr 4:13,255,856...13,270,185
JBrowse link
G Psmc4 proteasome 26S subunit, ATPase 4 increases expression EXP 2-nitrofluorene results in increased expression of PSMC4 mRNA CTD PMID:15890375 NCBI chr 1:83,349,127...83,357,497
Ensembl chr 1:83,348,592...83,357,494
JBrowse link
G Psmc5 proteasome 26S subunit, ATPase 5 increases expression EXP 2-nitrofluorene results in increased expression of PSMC5 mRNA CTD PMID:15890375 NCBI chr10:91,187,763...91,193,697
Ensembl chr10:91,187,743...91,213,135
JBrowse link
G Psmd1 proteasome 26S subunit, non-ATPase 1 increases expression EXP 2-nitrofluorene results in increased expression of PSMD1 mRNA CTD PMID:15890375 NCBI chr 9:86,709,714...86,785,213
Ensembl chr 9:86,709,947...86,785,211
JBrowse link
G Ptp4a1 protein tyrosine phosphatase 4A1 increases expression EXP 2-nitrofluorene results in increased expression of PTP4A1 mRNA CTD PMID:15890375 NCBI chr 9:33,214,201...33,245,046
Ensembl chr 9:33,214,208...33,221,964
JBrowse link
G Pttg1 PTTG1 regulator of sister chromatid separation, securin decreases expression EXP 2-nitrofluorene results in decreased expression of PTTG1 mRNA CTD PMID:15890375 NCBI chr10:27,893,466...27,904,965
Ensembl chr10:27,893,689...27,904,837
JBrowse link
G Rb1 RB transcriptional corepressor 1 decreases expression EXP 2-nitrofluorene results in decreased expression of RB1 mRNA CTD PMID:15890375 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
JBrowse link
G Rheb Ras homolog, mTORC1 binding increases expression EXP 2-nitrofluorene results in increased expression of RHEB mRNA CTD PMID:15890375 NCBI chr 4:10,278,970...10,320,160
Ensembl chr 4:10,279,370...10,320,160
JBrowse link
G Rhob ras homolog family member B increases expression EXP 2-nitrofluorene results in increased expression of RHOB mRNA CTD PMID:14600272 PMID:22484513 NCBI chr 6:31,363,752...31,365,926
Ensembl chr 6:31,363,548...31,366,108
JBrowse link
G Rpl10 ribosomal protein L10 increases expression EXP 2-nitrofluorene results in increased expression of RPL10 mRNA CTD PMID:15890375 NCBI chr  X:152,054,547...152,056,757
Ensembl chr  X:152,054,452...152,056,761
JBrowse link
G Rpl10a ribosomal protein L10A increases expression EXP 2-nitrofluorene results in increased expression of RPL10A mRNA CTD PMID:15890375 NCBI chr20:6,388,800...6,391,358
Ensembl chr20:6,385,823...6,391,357
JBrowse link
G Rpl13 ribosomal protein L13 increases expression EXP 2-nitrofluorene results in increased expression of RPL13 mRNA CTD PMID:15890375 NCBI chr19:51,153,990...51,156,541
Ensembl chr19:51,153,924...51,163,014
JBrowse link
G Rpl15 ribosomal protein L15 increases expression EXP 2-nitrofluorene results in increased expression of RPL15 mRNA CTD PMID:15890375 NCBI chr15:7,503,883...7,507,166
Ensembl chr15:7,503,883...7,507,165
JBrowse link
G Rpl17 ribosomal protein L17 increases expression EXP 2-nitrofluorene results in increased expression of RPL17 mRNA CTD PMID:15890375 NCBI chr18:68,581,147...68,584,253
Ensembl chr18:68,581,098...68,584,253
JBrowse link
G Rpl23 ribosomal protein L23 increases expression EXP 2-nitrofluorene results in increased expression of RPL23 mRNA CTD PMID:15890375 NCBI chr10:82,771,878...82,775,840
Ensembl chr10:82,771,538...82,775,870
JBrowse link
G Rpl6 ribosomal protein L6 increases expression EXP 2-nitrofluorene results in increased expression of RPL6 mRNA CTD PMID:15890375 NCBI chr12:35,347,493...35,352,011
Ensembl chr12:35,347,497...35,351,921
JBrowse link
G Rpl7a ribosomal protein L7a increases expression EXP 2-nitrofluorene results in increased expression of RPL7A mRNA CTD PMID:15890375 NCBI chr 3:10,239,026...10,241,703
Ensembl chr 3:10,239,001...10,241,716
JBrowse link
G Rpl8 ribosomal protein L8 increases expression EXP 2-nitrofluorene results in increased expression of RPL8 mRNA CTD PMID:15890375 NCBI chr 7:108,626,194...108,628,485
Ensembl chr 7:108,622,324...108,628,482
JBrowse link
G Rps15a ribosomal protein S15a increases expression EXP 2-nitrofluorene results in increased expression of RPS15A mRNA CTD PMID:15890375 NCBI chr 1:172,420,151...172,427,021
Ensembl chr 1:172,419,761...172,426,995
JBrowse link
G Rps19 ribosomal protein S19 increases expression EXP 2-nitrofluorene results in increased expression of RPS19 mRNA CTD PMID:14600272 PMID:15890375
G Rps24 ribosomal protein S24 increases expression EXP 2-nitrofluorene results in increased expression of RPS24 mRNA CTD PMID:15890375 NCBI chr16:89,538...94,267
Ensembl chr16:89,604...94,279
JBrowse link
G Rps27l ribosomal protein S27-like increases expression EXP 2-nitrofluorene results in increased expression of RPS27L mRNA CTD PMID:15890375 NCBI chr 8:67,562,483...67,567,418
Ensembl chr 8:67,562,483...67,567,418
JBrowse link
G Rps3 ribosomal protein S3 increases expression EXP 2-nitrofluorene results in increased expression of RPS3 mRNA CTD PMID:15890375 NCBI chr 1:153,778,363...153,783,663
Ensembl chr 1:153,777,472...153,783,680
JBrowse link
G Rps4x ribosomal protein S4, X-linked increases expression EXP 2-nitrofluorene results in increased expression of RPS4X mRNA CTD PMID:15890375 NCBI chr  X:67,298,522...67,302,965
Ensembl chr  X:67,298,525...67,303,019
JBrowse link
G Rps7 ribosomal protein S7 increases expression EXP 2-nitrofluorene results in increased expression of RPS7 mRNA CTD PMID:15890375 NCBI chr 6:45,266,200...45,271,064 JBrowse link
G Rpsa ribosomal protein SA increases expression EXP 2-nitrofluorene results in increased expression of RPSA mRNA CTD PMID:15890375 NCBI chr 8:119,851,225...119,855,103
Ensembl chr 8:119,851,225...119,855,247
JBrowse link
G Rsad2 radical S-adenosyl methionine domain containing 2 decreases expression EXP 2-nitrofluorene results in decreased expression of RSAD2 mRNA CTD PMID:22484513 NCBI chr 6:43,046,514...43,059,737
Ensembl chr 6:43,047,658...43,059,699
JBrowse link
G RT1-Bb RT1 class II, locus Bb increases expression EXP 2-nitrofluorene results in increased expression of RT1-BB mRNA CTD PMID:14600272 NCBI chr20:4,596,558...4,602,201
Ensembl chr20:4,596,559...4,607,597
JBrowse link
G RT1-Da RT1 class II, locus Da increases expression EXP 2-nitrofluorene results in increased expression of RT1-DA mRNA CTD PMID:14600272 NCBI chr20:4,513,464...4,518,457
Ensembl chr20:4,512,911...4,518,455
JBrowse link
G RT1-EC2 RT1 class Ib, locus EC2 increases expression EXP 2-nitrofluorene results in increased expression of RT1-EC2 mRNA CTD PMID:14600272
G Sds serine dehydratase decreases expression EXP 2-nitrofluorene results in decreased expression of SDS mRNA CTD PMID:14600272 NCBI chr12:36,083,226...36,090,540
Ensembl chr12:36,083,229...36,088,203
JBrowse link
G Selenow selenoprotein W increases expression EXP 2-nitrofluorene results in increased expression of SELENOW mRNA CTD PMID:15890375 NCBI chr 1:76,599,441...76,604,514
Ensembl chr 1:76,598,779...76,604,724
Ensembl chr 1:76,598,779...76,604,724
JBrowse link
G Serpina7 serpin family A member 7 increases expression EXP 2-nitrofluorene results in increased expression of SERPINA7 mRNA CTD PMID:14600272 NCBI chr  X:102,663,242...102,722,319
Ensembl chr  X:102,663,405...102,669,040
JBrowse link
G Sptan1 spectrin, alpha, non-erythrocytic 1 increases expression EXP 2-nitrofluorene results in increased expression of SPTAN1 mRNA CTD PMID:14600272 NCBI chr 3:13,241,164...13,306,047
Ensembl chr 3:13,241,217...13,306,046
JBrowse link
G Stat1 signal transducer and activator of transcription 1 increases expression EXP 2-nitrofluorene results in increased expression of STAT1 mRNA CTD PMID:14600272 NCBI chr 9:49,419,561...49,459,969 JBrowse link
G Stmn1 stathmin 1 increases expression EXP 2-nitrofluorene results in increased expression of STMN1 mRNA CTD PMID:15890375 NCBI chr 5:146,680,757...146,687,154
Ensembl chr 5:146,681,436...146,687,154
JBrowse link
G Tap1 transporter 1, ATP binding cassette subfamily B member increases expression EXP 2-nitrofluorene results in increased expression of TAP1 mRNA CTD PMID:14600272 NCBI chr20:4,656,262...4,666,634
Ensembl chr20:4,656,263...4,666,901
JBrowse link
G Tat tyrosine aminotransferase increases expression EXP 2-nitrofluorene results in increased expression of TAT mRNA CTD PMID:15890375 NCBI chr19:37,947,153...37,957,717
Ensembl chr19:37,947,112...37,958,031
JBrowse link
G Timm10b translocase of inner mitochondrial membrane 10B increases expression EXP 2-nitrofluorene results in increased expression of TIMM10B mRNA CTD PMID:15890375 NCBI chr 1:159,980,525...159,983,371
Ensembl chr 1:159,980,484...159,981,642
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 increases expression EXP 2-nitrofluorene results in increased expression of TIMP1 mRNA CTD PMID:14600272 PMID:15890375 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664
JBrowse link
G Tmsb10 thymosin, beta 10 increases expression EXP 2-nitrofluorene results in increased expression of TMSB10 mRNA CTD PMID:14600272 NCBI chr 4:105,009,959...105,011,095
Ensembl chr 4:105,009,212...105,011,028
JBrowse link
G Tnfaip3 TNF alpha induced protein 3 decreases expression
increases expression
ISO 2-nitrofluorene results in decreased expression of TNFAIP3 mRNA
2-nitrofluorene results in increased expression of TNFAIP3 mRNA
CTD PMID:21873647 NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282
JBrowse link
G Top2a DNA topoisomerase II alpha increases expression EXP 2-nitrofluorene results in increased expression of TOP2A mRNA CTD PMID:15890375 NCBI chr10:83,946,186...83,975,694
Ensembl chr10:83,945,735...83,976,874
JBrowse link
G Tpd52 tumor protein D52 decreases expression
increases expression
ISO 2-nitrofluorene results in decreased expression of TPD52 mRNA
2-nitrofluorene results in increased expression of TPD52 mRNA
CTD PMID:21873647 NCBI chr 2:92,735,246...92,816,079
Ensembl chr 2:92,735,620...92,816,622
JBrowse link
G Trappc10 trafficking protein particle complex subunit 10 increases expression EXP 2-nitrofluorene results in increased expression of TRAPPC10 mRNA CTD PMID:22484513 NCBI chr20:10,438,737...10,499,074
Ensembl chr20:10,438,737...10,499,074
JBrowse link
G Tsc22d1 TSC22 domain family, member 1 decreases expression EXP 2-nitrofluorene results in decreased expression of TSC22D1 mRNA CTD PMID:15890375 NCBI chr15:51,750,489...51,850,958
Ensembl chr15:51,749,510...51,850,958
JBrowse link
G Tuba1c tubulin, alpha 1C increases expression EXP 2-nitrofluorene results in increased expression of TUBA1C mRNA CTD PMID:15890375 NCBI chr 7:130,192,050...130,199,655
Ensembl chr 7:130,192,016...130,199,647
Ensembl chr  X:130,192,016...130,199,647
JBrowse link
G Tubb5 tubulin, beta 5 class I increases expression EXP 2-nitrofluorene results in increased expression of TUBB5 mRNA CTD PMID:15890375 NCBI chr20:2,912,779...2,916,928
Ensembl chr20:2,912,778...2,916,940
JBrowse link
G Tyms thymidylate synthetase increases expression EXP 2-nitrofluorene results in increased expression of TYMS mRNA CTD PMID:14600272 PMID:15890375 PMID:23052194 NCBI chr 9:113,313,454...113,329,551
Ensembl chr 9:113,313,452...113,329,536
JBrowse link
G Ugt1a7c UDP glucuronosyltransferase 1 family, polypeptide A7C increases expression EXP 2-nitrofluorene results in increased expression of UGT1A7 mRNA CTD PMID:14600272 NCBI chr 9:88,739,577...88,808,465 JBrowse link
G Ugt2b17 UDP glucuronosyltransferase family 2 member B17 increases expression EXP 2-nitrofluorene results in increased expression of UGT2B17 mRNA CTD PMID:23052194 NCBI chr14:21,024,035...21,035,784
Ensembl chr14:21,024,006...21,035,986
JBrowse link
G Vegfa vascular endothelial growth factor A increases expression EXP 2-nitrofluorene results in increased expression of VEGFA mRNA CTD PMID:15890375 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
G Vim vimentin increases expression EXP 2-nitrofluorene results in increased expression of VIM mRNA CTD PMID:14600272 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
JBrowse link
G Xdh xanthine dehydrogenase decreases expression
increases reduction
EXP
ISO
2-nitrofluorene results in decreased expression of XDH mRNA
XDH protein results in increased reduction of 2-nitrofluorene
CTD PMID:15890375 PMID:15932950 NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268
JBrowse link
G Zmat3 zinc finger, matrin type 3 increases expression EXP 2-nitrofluorene results in increased expression of ZMAT3 mRNA CTD PMID:14600272 PMID:15890375 NCBI chr 2:115,106,050...115,136,863
Ensembl chr 2:115,106,966...115,136,863
JBrowse link
2-nitropropane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1b ATP-binding cassette, subfamily B (MDR/TAP), member 1B increases expression EXP 2-nitropropane results in increased expression of ABCB1B mRNA CTD PMID:17070881 NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199
JBrowse link
G Acmsd aminocarboxymuconate semialdehyde decarboxylase decreases expression EXP 2-nitropropane results in decreased expression of ACMSD mRNA CTD PMID:17070881 NCBI chr13:39,200,486...39,244,337
Ensembl chr13:39,200,314...39,245,209
JBrowse link
G Acsl3 acyl-CoA synthetase long-chain family member 3 increases expression EXP 2-nitropropane results in increased expression of ACSL3 mRNA CTD PMID:17070881 NCBI chr 9:80,140,996...80,164,636
Ensembl chr 9:80,115,112...80,164,627
JBrowse link
G Aen apoptosis enhancing nuclease increases expression EXP 2-nitropropane results in increased expression of AEN mRNA CTD PMID:17070881 NCBI chr 1:132,815,094...132,824,522
Ensembl chr 1:132,815,142...132,824,523
JBrowse link
G Afp alpha-fetoprotein multiple interactions
increases expression
EXP diphenyldiselenide inhibits the reaction [2-nitropropane results in increased expression of AFP protein] CTD PMID:15804453 NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480
JBrowse link
G Akr7a3 aldo-keto reductase family 7 member A3 increases expression EXP 2-nitropropane results in increased expression of AKR7A3 mRNA CTD PMID:17070881 NCBI chr 5:151,590,968...151,601,394
Ensembl chr 5:151,584,479...151,601,394
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 increases expression EXP 2-nitropropane results in increased expression of ALDH1A1 mRNA CTD PMID:17070881 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
JBrowse link
G Aldh1a7 aldehyde dehydrogenase family 1, subfamily A7 increases expression EXP 2-nitropropane results in increased expression of ALDH1A4 mRNA CTD PMID:17070881 NCBI chr 1:218,201,443...218,241,410
Ensembl chr 1:218,201,472...218,248,906
JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 affects response to substance
increases expression
multiple interactions
ISO APEX1 protein affects the susceptibility to 2-nitropropane
2-nitropropane results in increased expression of APEX1 mRNA; 2-nitropropane results in increased expression of APEX1 protein
APEX1 protein inhibits the reaction [2-nitropropane results in increased activity of CASP3 protein]; APEX1 protein inhibits the reaction [2-nitropropane results in increased expression of GADD45G mRNA]; APEX1 protein inhibits the reaction [2-nitropropane results in increased expression of TRP53 protein]
CTD PMID:19268524 NCBI chr15:24,144,595...24,146,785
Ensembl chr15:24,144,362...24,146,785
JBrowse link
G Apoa2 apolipoprotein A2 decreases expression EXP 2-nitropropane results in decreased expression of APOA2 mRNA CTD PMID:17070881 NCBI chr13:83,644,460...83,646,358
Ensembl chr13:83,644,470...83,646,355
JBrowse link
G Apoa4 apolipoprotein A4 decreases expression EXP 2-nitropropane results in decreased expression of APOA4 mRNA CTD PMID:17070881 NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469
JBrowse link
G Apoc3 apolipoprotein C3 decreases expression EXP 2-nitropropane results in decreased expression of APOC3 mRNA CTD PMID:17070881 NCBI chr 8:46,531,478...46,533,658
Ensembl chr 8:46,531,478...46,533,583
JBrowse link
G Atp6v1d ATPase H+ transporting V1 subunit D increases expression EXP 2-nitropropane results in increased expression of ATP6V1D mRNA CTD PMID:17070881 NCBI chr 6:97,656,725...97,672,211
Ensembl chr 6:97,656,576...97,672,303
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression EXP 2-nitropropane results in increased expression of BAX mRNA CTD PMID:17070881 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Btg2 BTG anti-proliferation factor 2 increases expression EXP 2-nitropropane results in increased expression of BTG2 mRNA CTD PMID:17070881 NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628
JBrowse link
G C7 complement C7 increases expression EXP 2-nitropropane results in increased expression of C7 mRNA CTD PMID:17070881 NCBI chr 2:54,088,116...54,165,102
Ensembl chr 2:54,088,116...54,158,535
JBrowse link
G Casp3 caspase 3 increases activity
multiple interactions
ISO 2-nitropropane results in increased activity of CASP3 protein
APEX1 protein inhibits the reaction [2-nitropropane results in increased activity of CASP3 protein]
CTD PMID:19268524 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Cat catalase decreases activity
multiple interactions
EXP 2-nitropropane results in decreased activity of CAT protein
diphenyldiselenide inhibits the reaction [2-nitropropane results in decreased activity of CAT protein]; m-trifluoromethyl-diphenyl diselenide inhibits the reaction [2-nitropropane results in decreased activity of CAT protein]
CTD PMID:16445897 PMID:18818063 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cblc Cbl proto-oncogene C increases expression EXP 2-nitropropane results in increased expression of CBLC mRNA CTD PMID:17070881 NCBI chr 1:79,439,975...79,456,755
Ensembl chr 1:79,439,977...79,456,755
JBrowse link
G Ccng1 cyclin G1 increases expression EXP 2-nitropropane results in increased expression of CCNG1 mRNA CTD PMID:17070881 NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641
JBrowse link
G Cd276 Cd276 molecule increases expression EXP 2-nitropropane results in increased expression of CD276 mRNA CTD PMID:17070881 NCBI chr 8:58,937,751...58,968,082
Ensembl chr 8:58,937,751...58,968,380
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression EXP 2-nitropropane results in increased expression of CDKN1A mRNA CTD PMID:17070881 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cpq carboxypeptidase Q decreases expression EXP 2-nitropropane results in decreased expression of CPQ mRNA CTD PMID:17070881 NCBI chr 7:64,264,025...64,830,867
Ensembl chr 7:64,264,081...64,724,546
JBrowse link
G Cryab crystallin, alpha B increases expression EXP 2-nitropropane results in increased expression of CRYAB mRNA CTD PMID:17070881 NCBI chr 8:51,093,441...51,099,161
Ensembl chr 8:51,093,441...51,099,157
JBrowse link
G Cyp2c13 cytochrome P450, family 2, subfamily c, polypeptide 13 increases expression EXP 2-nitropropane results in increased expression of CYP2C13 mRNA CTD PMID:17070881 NCBI chr 1:238,786,764...238,867,195
Ensembl chr 1:238,786,765...238,867,191
JBrowse link
G Cyp4f5 cytochrome P450, family 4, subfamily f, polypeptide 5 increases expression EXP 2-nitropropane results in increased expression of CYP4F5 mRNA CTD PMID:17070881 NCBI chr 7:11,544,040...11,558,982
Ensembl chr 7:11,544,082...11,558,978
JBrowse link
G Ddah1 dimethylarginine dimethylaminohydrolase 1 increases expression EXP 2-nitropropane results in increased expression of DDAH1 mRNA CTD PMID:17070881 NCBI chr 2:234,667,499...234,800,322
Ensembl chr 2:234,667,491...234,799,339
JBrowse link
G Epcam epithelial cell adhesion molecule increases expression EXP 2-nitropropane results in increased expression of EPCAM mRNA CTD PMID:17070881 NCBI chr 6:6,880,142...6,896,103
Ensembl chr 6:6,878,237...6,896,127
JBrowse link
G Ephx1 epoxide hydrolase 1 increases expression EXP 2-nitropropane results in increased expression of EPHX1 mRNA CTD PMID:17070881 NCBI chr13:92,714,315...92,744,124
Ensembl chr13:92,714,315...92,790,235
JBrowse link
G Fas Fas cell surface death receptor increases expression EXP 2-nitropropane results in increased expression of FAS mRNA CTD PMID:17070881 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Fhit fragile histidine triad diadenosine triphosphatase decreases expression EXP 2-nitropropane results in decreased expression of FHIT mRNA CTD PMID:17070881 NCBI chr15:13,935,029...15,442,620
Ensembl chr15:13,934,995...15,442,340
JBrowse link
G Gadd45g growth arrest and DNA-damage-inducible, gamma increases expression
multiple interactions
ISO 2-nitropropane results in increased expression of GADD45G mRNA
APEX1 protein inhibits the reaction [2-nitropropane results in increased expression of GADD45G mRNA]
CTD PMID:19268524 NCBI chr17:13,376,842...13,378,587
Ensembl chr17:13,376,839...13,378,610
JBrowse link
G Gria3 glutamate ionotropic receptor AMPA type subunit 3 increases expression EXP 2-nitropropane results in increased expression of GRIA3 mRNA CTD PMID:17070881 NCBI chr  X:120,238,515...120,504,106
Ensembl chr  X:120,238,534...120,504,096
JBrowse link
G Gstm1 glutathione S-transferase mu 1 increases expression EXP 2-nitropropane results in increased expression of GSTM1 mRNA CTD PMID:17070881 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
JBrowse link
G Hsd17b6 hydroxysteroid (17-beta) dehydrogenase 6 decreases expression EXP 2-nitropropane results in decreased expression of HSD17B6 mRNA CTD PMID:17070881 NCBI chr 7:422,466...442,008
Ensembl chr 7:422,480...442,425
JBrowse link
G Il2ra interleukin 2 receptor subunit alpha increases expression EXP 2-nitropropane results in increased expression of IL2RA mRNA CTD PMID:17070881 NCBI chr17:66,849,974...66,898,665
Ensembl chr17:66,849,974...66,898,697
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase increases expression EXP 2-nitropropane results in increased expression of MGMT mRNA CTD PMID:17070881 NCBI chr 1:191,710,980...191,937,760
Ensembl chr 1:191,710,930...191,937,756
JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator decreases expression EXP 2-nitropropane results in decreased expression of NUPR1 mRNA CTD PMID:17070881 NCBI chr 1:181,213,292...181,215,327 JBrowse link
G Olr37 olfactory receptor 37 decreases expression EXP 2-nitropropane results in decreased expression of OLR37 mRNA CTD PMID:17070881 NCBI chr 1:154,089,219...154,090,184 JBrowse link
G Phlda3 pleckstrin homology-like domain, family A, member 3 increases expression EXP 2-nitropropane results in increased expression of PHLDA3 mRNA CTD PMID:17070881 NCBI chr13:47,193,250...47,196,335
Ensembl chr13:47,193,086...47,196,335
JBrowse link
G Polb DNA polymerase beta multiple interactions ISO 2-nitropropane results in increased expression of and results in increased activity of POLB protein; POLB protein inhibits the reaction [2-nitropropane results in increased expression of TRP53 protein] CTD PMID:12189182 NCBI chr16:69,379,438...69,402,710
Ensembl chr16:69,379,400...69,404,812
JBrowse link
G Rhobtb2 Rho-related BTB domain containing 2 increases expression EXP 2-nitropropane results in increased expression of RHOBTB2 mRNA CTD PMID:17070881 NCBI chr15:44,868,251...44,888,436
Ensembl chr15:44,870,376...44,888,651
JBrowse link
G Serpina7 serpin family A member 7 increases expression EXP 2-nitropropane results in increased expression of SERPINA7 mRNA CTD PMID:17070881 NCBI chr  X:102,663,242...102,722,319
Ensembl chr  X:102,663,405...102,669,040
JBrowse link
G Slc16a10 solute carrier family 16 member 10 decreases expression EXP 2-nitropropane results in decreased expression of SLC16A10 mRNA CTD PMID:17070881 NCBI chr20:43,454,819...43,567,839
Ensembl chr20:43,459,709...43,567,839
JBrowse link
G Spink1 serine peptidase inhibitor, Kazal type 1 decreases expression EXP 2-nitropropane results in decreased expression of SPINK1 mRNA CTD PMID:17070881 NCBI chr18:35,870,723...35,882,693
Ensembl chr18:35,824,550...35,882,642
JBrowse link
G Sugct succinylCoA:glutarate-CoA transferase decreases expression EXP 2-nitropropane results in decreased expression of SUGCT mRNA CTD PMID:17070881 NCBI chr17:47,376,392...48,234,362
Ensembl chr17:47,376,521...48,234,376
JBrowse link
G Sulf2 sulfatase 2 increases expression EXP 2-nitropropane results in increased expression of SULF2 mRNA CTD PMID:17070881 NCBI chr 3:154,822,079...154,904,566
Ensembl chr 3:154,822,085...154,904,415
JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 decreases expression EXP 2-nitropropane results in decreased expression of SULT2A1 mRNA CTD PMID:17070881 NCBI chr 1:75,451,178...75,508,142 JBrowse link
G Tp53 tumor protein p53 multiple interactions
increases expression
ISO APEX1 protein inhibits the reaction [2-nitropropane results in increased expression of TRP53 protein]; POLB protein inhibits the reaction [2-nitropropane results in increased expression of TRP53 protein] CTD PMID:12189182 PMID:16720738 PMID:19268524 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Zmat3 zinc finger, matrin type 3 increases expression EXP 2-nitropropane results in increased expression of ZMAT3 mRNA CTD PMID:17070881 NCBI chr 2:115,106,050...115,136,863
Ensembl chr 2:115,106,966...115,136,863
JBrowse link
3-Nitrofluoranthene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor multiple interactions ISO 3-nitrofluoranthene binds to and results in increased activity of AHR protein CTD PMID:28186253 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Akt1 AKT serine/threonine kinase 1 increases phosphorylation ISO 3-nitrofluoranthene results in increased phosphorylation of AKT1 protein CTD PMID:19041363 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Casp3 caspase 3 increases activity ISO 3-nitrofluoranthene results in increased activity of CASP3 protein CTD PMID:19041363 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp8 caspase 8 increases activity ISO 3-nitrofluoranthene results in increased activity of CASP8 protein CTD PMID:19041363 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 increases activity ISO 3-nitrofluoranthene results in increased activity of CASP9 protein CTD PMID:19041363 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Ccl20 C-C motif chemokine ligand 20 increases expression ISO 3-nitrofluoranthene results in increased expression of CCL20 mRNA CTD PMID:19879285 NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629
JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 increases expression ISO 3-nitrofluoranthene results in increased expression of CXCL1 mRNA CTD PMID:19879285 NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 increases expression ISO 3-nitrofluoranthene results in increased expression of CXCL10 mRNA CTD PMID:19879285 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 increases expression ISO 3-nitrofluoranthene results in increased expression of CXCL1 mRNA CTD PMID:19879285 NCBI chr14:17,270,146...17,289,458
Ensembl chr14:17,270,146...17,289,511
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression ISO 3-nitrofluoranthene results in increased expression of CYP1A1 protein
3-nitrofluoranthene results in increased expression of CYP1A1 mRNA
CTD PMID:12107646 PMID:19041363 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression ISO 3-nitrofluoranthene results in increased expression of CYP1A2 mRNA CTD PMID:12107646 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions ISO [CYP1B1 protein co-treated with POR protein] results in decreased metabolism of 3-nitrofluoranthene CTD PMID:11113705 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO 3-nitrofluoranthene results in increased expression of HMOX1 protein CTD PMID:28633978 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Il6 interleukin 6 increases expression ISO 3-nitrofluoranthene results in increased expression of IL6 mRNA CTD PMID:19879285 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Ltb lymphotoxin beta increases expression ISO 3-nitrofluoranthene results in increased expression of LTB mRNA CTD PMID:19879285 NCBI chr20:3,627,536...3,629,381
Ensembl chr20:3,627,537...3,629,381
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta increases expression ISO 3-nitrofluoranthene results in increased expression of MAP1LC3B protein CTD PMID:19041363 NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation ISO 3-nitrofluoranthene results in increased phosphorylation of MAPK1 protein CTD PMID:19041363 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation ISO 3-nitrofluoranthene results in increased phosphorylation of MAPK3 protein CTD PMID:19041363 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 multiple interactions ISO 3-nitrofluoranthene results in increased expression of and affects the localization of and results in increased activity of NFE2L2 protein CTD PMID:28633978 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage ISO 3-nitrofluoranthene results in increased cleavage of PARP1 protein CTD PMID:19041363 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Por cytochrome p450 oxidoreductase multiple interactions ISO [CYP1B1 protein co-treated with POR protein] results in decreased metabolism of 3-nitrofluoranthene CTD PMID:11113705 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245
JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit increases expression ISO 3-nitrofluoranthene results in increased expression of PRKDC protein CTD PMID:28633978 NCBI chr11:85,040,790...85,258,357
Ensembl chr11:85,040,792...85,257,952
JBrowse link
G Tnf tumor necrosis factor increases expression
multiple interactions
ISO 3-nitrofluoranthene results in increased expression of TNF mRNA
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [3-nitrofluoranthene results in increased expression of TNF mRNA]; MK 2206 inhibits the reaction [3-nitrofluoranthene results in increased expression of TNF mRNA]
CTD PMID:19879285 PMID:28633978 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO 3-nitrofluoranthene results in increased phosphorylation of and affects the localization of TRP53 protein CTD PMID:19041363 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
5-Nitroacenaphthene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor multiple interactions ISO 5-nitroacenaphthene binds to and results in increased activity of AHR protein CTD PMID:28186253 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
nimesulide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aadac arylacetamide deacetylase decreases expression EXP nimesulide results in decreased expression of AADAC mRNA CTD PMID:24136188 NCBI chr 2:144,163,436...144,186,086
Ensembl chr 2:144,135,319...144,174,734
JBrowse link
G Abat 4-aminobutyrate aminotransferase decreases expression EXP nimesulide results in decreased expression of ABAT mRNA CTD PMID:24136188 NCBI chr10:6,996,688...7,092,835
Ensembl chr10:6,999,819...7,092,835
JBrowse link
G Abca1 ATP binding cassette subfamily A member 1 decreases expression EXP nimesulide results in decreased expression of ABCA1 mRNA CTD PMID:24136188 NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A decreases expression
increases expression
ISO nimesulide results in decreased expression of ABCB1 protein
nimesulide results in increased expression of ABCB1 mRNA
CTD PMID:21745461 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcb6 ATP binding cassette subfamily B member 6 increases expression EXP nimesulide results in increased expression of ABCB6 mRNA CTD PMID:24136188 NCBI chr 9:76,668,554...76,677,263
Ensembl chr 9:76,668,554...76,676,924
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 increases expression ISO nimesulide results in increased expression of ABCC1 mRNA CTD PMID:21745461 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 increases expression EXP nimesulide results in increased expression of ABCC2 mRNA CTD PMID:24136188 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 increases expression EXP nimesulide results in increased expression of ABCC3 mRNA CTD PMID:24136188 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595
JBrowse link
G Abce1 ATP binding cassette subfamily E member 1 increases expression EXP nimesulide results in increased expression of ABCE1 mRNA CTD PMID:24136188 NCBI chr19:28,205,566...28,230,489
Ensembl chr19:28,205,555...28,230,489
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 decreases activity
decreases expression
ISO nimesulide results in decreased activity of ABCG2 protein
nimesulide results in decreased expression of ABCG2 protein
CTD PMID:18581209 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409
JBrowse link
G Abcg3l2 ATP-binding cassette, subfamily G (WHITE), member 3-like 2 decreases expression EXP nimesulide results in decreased expression of ABCG3L2 mRNA CTD PMID:24136188 NCBI chr14:4,493,259...4,538,264
Ensembl chr14:4,493,262...4,533,306
JBrowse link
G Acaa1a acetyl-CoA acyltransferase 1A increases expression EXP nimesulide results in increased expression of ACAA1 mRNA CTD PMID:24136188 NCBI chr 8:119,079,401...119,088,624
Ensembl chr 8:119,079,775...119,088,624
JBrowse link
G Acaa2 acetyl-CoA acyltransferase 2 increases expression EXP nimesulide results in increased expression of ACAA2 mRNA CTD PMID:24136188 NCBI chr18:68,345,136...68,373,246
Ensembl chr18:68,345,012...68,373,249
JBrowse link
G Acaca acetyl-CoA carboxylase alpha decreases expression EXP nimesulide results in decreased expression of ACACA mRNA CTD PMID:24136188 NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457
JBrowse link
G Ace2 angiotensin I converting enzyme 2 decreases expression ISO
EXP
nimesulide results in decreased expression of ACE2 mRNA CTD PMID:32808185 NCBI chr  X:30,293,597...30,340,961
Ensembl chr  X:30,293,589...30,340,977
JBrowse link
G Acly ATP citrate lyase decreases expression EXP nimesulide results in decreased expression of ACLY mRNA CTD PMID:24136188 NCBI chr10:85,412,045...85,464,253
Ensembl chr10:85,412,049...85,463,320
JBrowse link
G Aco1 aconitase 1 increases expression EXP nimesulide results in increased expression of ACO1 mRNA CTD PMID:24136188 NCBI chr 5:55,259,841...55,315,872
Ensembl chr 5:55,259,827...55,316,391
JBrowse link
G Aco2 aconitase 2 increases expression EXP nimesulide results in increased expression of ACO2 mRNA CTD PMID:24136188 NCBI chr 7:113,385,677...113,428,794
Ensembl chr 7:113,385,646...113,428,261
JBrowse link
G Acot2 acyl-CoA thioesterase 2 increases expression EXP nimesulide results in increased expression of ACOT2 mRNA CTD PMID:24136188 NCBI chr 6:103,611,744...103,619,404
Ensembl chr 6:103,611,544...103,619,245
JBrowse link
G Acot7 acyl-CoA thioesterase 7 increases expression EXP nimesulide results in increased expression of ACOT7 mRNA CTD PMID:24136188 NCBI chr 5:162,686,562...162,779,309
Ensembl chr 5:162,684,645...162,779,309
JBrowse link
G Acox3 acyl-CoA oxidase 3, pristanoyl decreases expression EXP nimesulide results in decreased expression of ACOX3 mRNA CTD PMID:24136188 NCBI chr14:75,133,986...75,176,767
Ensembl chr14:75,094,676...75,176,205
JBrowse link
G Acsf2 acyl-CoA synthetase family member 2 decreases expression EXP nimesulide results in decreased expression of ACSF2 mRNA CTD PMID:24136188 NCBI chr10:79,504,510...79,546,714
Ensembl chr10:79,504,511...79,546,673
JBrowse link
G Acsl1 acyl-CoA synthetase long-chain family member 1 decreases expression EXP nimesulide results in decreased expression of ACSL1 mRNA CTD PMID:24136188 NCBI chr16:45,755,246...45,821,541
Ensembl chr16:45,755,254...45,821,541
JBrowse link
G Acsl4 acyl-CoA synthetase long-chain family member 4 increases expression EXP nimesulide results in increased expression of ACSL4 mRNA CTD PMID:24136188 NCBI chr  X:105,942,794...106,006,573
Ensembl chr  X:105,942,799...106,006,427
JBrowse link
G Acsl5 acyl-CoA synthetase long-chain family member 5 decreases expression EXP nimesulide results in decreased expression of ACSL5 mRNA CTD PMID:24136188 NCBI chr 1:254,289,513...254,336,608
Ensembl chr 1:254,292,521...254,336,607
JBrowse link
G Adamts7 ADAM metallopeptidase with thrombospondin type 1 motif, 7 decreases expression EXP nimesulide results in decreased expression of ADAMTS7 mRNA CTD PMID:24136188 NCBI chr 8:90,704,727...90,744,331
Ensembl chr 8:90,704,727...90,744,328
JBrowse link
G Adck5 aarF domain containing kinase 5 increases expression EXP nimesulide results in increased expression of ADCK5 mRNA CTD PMID:24136188 NCBI chr 7:108,301,623...108,319,439
Ensembl chr 7:108,301,415...108,319,436
JBrowse link
G Add1 adducin 1 increases expression EXP nimesulide results in increased expression of ADD1 mRNA CTD PMID:24136188 NCBI chr14:76,108,643...76,167,267
Ensembl chr14:76,108,654...76,167,182
JBrowse link
G Adgrl2 adhesion G protein-coupled receptor L2 decreases expression EXP nimesulide results in decreased expression of ADGRL2 mRNA CTD PMID:24136188 NCBI chr 2:237,696,055...238,327,141
Ensembl chr 2:237,696,056...238,327,141
JBrowse link
G Adhfe1 alcohol dehydrogenase, iron containing, 1 decreases expression EXP nimesulide results in decreased expression of ADHFE1 mRNA CTD PMID:24136188 NCBI chr 5:9,705,966...9,732,580
Ensembl chr 5:9,705,970...9,732,517
JBrowse link
G Adipor2 adiponectin receptor 2 decreases expression EXP nimesulide results in decreased expression of ADIPOR2 mRNA CTD PMID:24136188 NCBI chr 4:152,524,604...152,588,848
Ensembl chr 4:152,524,623...152,559,355
JBrowse link
G Adprm ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent increases expression EXP nimesulide results in increased expression of ADPRM mRNA CTD PMID:24136188 NCBI chr10:51,732,073...51,744,635
Ensembl chr10:51,731,993...51,744,635
JBrowse link
G Adrm1 ADRM1 26S proteasome ubiquitin receptor increases expression EXP nimesulide results in increased expression of ADRM1 mRNA CTD PMID:24136188 NCBI chr 3:167,265,435...167,270,197
Ensembl chr 3:167,265,296...167,270,195
JBrowse link
G Adsl adenylosuccinate lyase increases expression EXP nimesulide results in increased expression of ADSL mRNA CTD PMID:24136188 NCBI chr 7:112,479,256...112,503,439
Ensembl chr 7:112,479,271...112,503,760
JBrowse link
G Afm afamin decreases expression EXP nimesulide results in decreased expression of AFM mRNA CTD PMID:24136188 NCBI chr14:17,531,026...17,563,868
Ensembl chr14:17,531,024...17,563,870
JBrowse link
G Agt angiotensinogen decreases activity ISO nimesulide results in decreased activity of AGT CTD PMID:12065685 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
JBrowse link
G Agxt alanine--glyoxylate and serine--pyruvate aminotransferase decreases expression EXP nimesulide results in decreased expression of AGXT mRNA CTD PMID:24136188 NCBI chr 9:93,675,384...93,685,337
Ensembl chr 9:93,675,384...93,685,336
JBrowse link
G Agxt2 alanine-glyoxylate aminotransferase 2 decreases expression EXP nimesulide results in decreased expression of AGXT2 mRNA CTD PMID:24136188 NCBI chr 2:59,336,252...59,377,664
Ensembl chr 2:59,336,283...59,377,926
JBrowse link
G Ahsa1 activator of Hsp90 ATPase activity 1 increases expression EXP nimesulide results in increased expression of AHSA1 mRNA CTD PMID:24136188 NCBI chr 6:106,913,296...106,921,347
Ensembl chr 6:106,913,530...106,921,345
JBrowse link
G Aif1 allograft inflammatory factor 1 decreases expression EXP nimesulide results in decreased expression of AIF1 mRNA CTD PMID:24136188 NCBI chr20:3,646,784...3,652,670
Ensembl chr20:3,646,777...3,652,668
JBrowse link
G Aig1 androgen-induced 1 increases expression EXP nimesulide results in increased expression of AIG1 mRNA CTD PMID:24136188 NCBI chr 1:8,046,430...8,269,276
Ensembl chr 1:8,046,430...8,269,084
JBrowse link
G Aimp2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 increases expression EXP nimesulide results in increased expression of AIMP2 mRNA CTD PMID:24136188 NCBI chr12:10,701,194...10,710,772
Ensembl chr12:10,701,194...10,710,769
JBrowse link
G Ak4 adenylate kinase 4 decreases expression EXP nimesulide results in decreased expression of AK4 mRNA CTD PMID:24136188 NCBI chr 5:116,039,222...116,099,064
Ensembl chr 5:116,039,616...116,098,618
JBrowse link
G Akr1a1 aldo-keto reductase family 1 member A1 increases expression EXP nimesulide results in increased expression of AKR1A1 mRNA CTD PMID:24136188 NCBI chr 5:130,092,945...130,130,277
Ensembl chr 5:130,092,732...130,113,674
JBrowse link
G Akr7a2 aldo-keto reductase family 7, member A2 increases expression EXP nimesulide results in increased expression of AKR7A2 mRNA CTD PMID:24136188 NCBI chr 5:151,552,375...151,560,914
Ensembl chr 5:151,552,343...151,560,909
JBrowse link
G Akr7a3 aldo-keto reductase family 7 member A3 increases expression EXP nimesulide results in increased expression of AKR7A3 mRNA CTD PMID:24136188 NCBI chr 5:151,590,968...151,601,394
Ensembl chr 5:151,584,479...151,601,394
JBrowse link
G Akt1s1 AKT1 substrate 1 increases expression EXP nimesulide results in increased expression of AKT1S1 mRNA CTD PMID:24136188 NCBI chr 1:95,333,186...95,339,678
Ensembl chr 1:95,332,898...95,339,677
JBrowse link
G Alas1 5'-aminolevulinate synthase 1 increases expression EXP nimesulide results in increased expression of ALAS1 mRNA CTD PMID:24136188 NCBI chr 8:106,876,514...106,889,852
Ensembl chr 8:106,876,514...106,889,917
JBrowse link
G Alcam activated leukocyte cell adhesion molecule decreases expression EXP nimesulide results in decreased expression of ALCAM mRNA CTD PMID:24136188 NCBI chr11:48,336,123...48,536,296
Ensembl chr11:48,336,169...48,537,954
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 increases expression EXP nimesulide results in increased expression of ALDH1A1 mRNA CTD PMID:24136188 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
JBrowse link
G Aldh1b1 aldehyde dehydrogenase 1 family, member B1 decreases expression EXP nimesulide results in decreased expression of ALDH1B1 mRNA CTD PMID:24136188 NCBI chr 5:60,063,370...60,068,378
Ensembl chr 5:60,063,225...60,068,378
JBrowse link
G Alg12 ALG12, alpha-1,6-mannosyltransferase increases expression EXP nimesulide results in increased expression of ALG12 mRNA CTD PMID:24136188 NCBI chr 7:119,895,112...119,909,488
Ensembl chr 7:119,895,120...119,909,458
JBrowse link
G Alg14 ALG14, UDP-N-acetylglucosaminyltransferase subunit increases expression EXP nimesulide results in increased expression of ALG14 mRNA CTD PMID:24136188 NCBI chr 2:209,368,285...209,445,425
Ensembl chr 2:209,368,312...209,445,431
JBrowse link
G Amy1a amylase, alpha 1A decreases expression EXP nimesulide results in decreased expression of AMY1A mRNA CTD PMID:24136188 NCBI chr 2:201,382,678...201,397,487
Ensembl chr 2:201,382,675...201,397,816
JBrowse link
G Ang angiogenin decreases expression EXP nimesulide results in decreased expression of ANG mRNA CTD PMID:24136188 NCBI chr15:24,317,733...24,323,361 JBrowse link
G Angptl3 angiopoietin-like 3 decreases expression EXP nimesulide results in decreased expression of ANGPTL3 mRNA CTD PMID:24136188 NCBI chr 5:113,703,007...113,710,044
Ensembl chr 5:113,703,012...113,709,957
JBrowse link
G Angptl4 angiopoietin-like 4 increases expression ISO nimesulide results in increased expression of ANGPTL4 mRNA CTD PMID:19415698 NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519
JBrowse link
G Ankh ANKH inorganic pyrophosphate transport regulator decreases expression EXP nimesulide results in decreased expression of ANKH mRNA CTD PMID:24136188 NCBI chr 2:78,153,027...78,280,181
Ensembl chr 2:78,153,026...78,280,187
JBrowse link
G Ankrd24 ankyrin repeat domain 24 increases expression EXP nimesulide results in increased expression of ANKRD24 mRNA CTD PMID:24136188 NCBI chr 7:8,061,634...8,081,142
Ensembl chr 7:8,061,953...8,081,142
JBrowse link
G Anpep alanyl aminopeptidase, membrane decreases expression EXP nimesulide results in decreased expression of ANPEP mRNA CTD PMID:24136188 NCBI chr 1:133,767,332...133,810,137
Ensembl chr 1:133,767,332...133,785,789
JBrowse link
G Anxa3 annexin A3 decreases expression EXP nimesulide results in decreased expression of ANXA3 mRNA CTD PMID:24136188 NCBI chr14:12,727,708...12,781,717
Ensembl chr14:12,719,795...12,781,617
JBrowse link
G Anxa4 annexin A4 increases expression EXP nimesulide results in increased expression of ANXA4 mRNA CTD PMID:24136188 NCBI chr 4:119,184,378...119,241,183
Ensembl chr 4:119,184,374...119,241,161
JBrowse link
G Anxa5 annexin A5 decreases expression EXP nimesulide results in decreased expression of ANXA5 mRNA CTD PMID:24136188 NCBI chr 2:119,314,007...119,344,703
Ensembl chr 2:119,314,007...119,353,369
JBrowse link
G Anxa7 annexin A7 increases expression EXP nimesulide results in increased expression of ANXA7 mRNA CTD PMID:24136188 NCBI chr15:3,821,798...3,849,659
Ensembl chr15:3,821,845...3,849,385
JBrowse link
G Aopep aminopeptidase O decreases expression EXP nimesulide results in decreased expression of AOPEP mRNA CTD PMID:24136188 NCBI chr17:1,811,922...2,127,316
Ensembl chr17:1,811,980...2,127,331
JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 increases expression EXP nimesulide results in increased expression of APEX1 mRNA CTD PMID:24136188 NCBI chr15:24,144,595...24,146,785
Ensembl chr15:24,144,362...24,146,785
JBrowse link
G Aplp2 amyloid beta precursor like protein 2 decreases expression EXP nimesulide results in decreased expression of APLP2 mRNA CTD PMID:24136188 NCBI chr 8:29,599,230...29,662,311
Ensembl chr 8:29,599,230...29,661,855
JBrowse link
G Apmap adipocyte plasma membrane associated protein decreases expression EXP nimesulide results in decreased expression of APMAP mRNA CTD PMID:24136188 NCBI chr 3:139,409,020...139,437,296
Ensembl chr 3:139,409,022...139,437,341
JBrowse link
G Apoa5 apolipoprotein A5 decreases expression EXP nimesulide results in decreased expression of APOA5 mRNA CTD PMID:24136188 NCBI chr 8:46,561,180...46,563,818
Ensembl chr 8:46,561,229...46,563,816
JBrowse link
G Apoe apolipoprotein E multiple interactions ISO nimesulide inhibits the reaction [APOE results in decreased expression of CCNA2 protein]; nimesulide inhibits the reaction [APOE results in increased abundance of 6-Ketoprostaglandin F1 alpha] CTD PMID:14966570 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
G Apol3 apolipoprotein L, 3 decreases expression EXP nimesulide results in decreased expression of APOL3 mRNA CTD PMID:24136188 NCBI chr 7:109,288,725...109,297,728
Ensembl chr 7:109,288,725...109,297,723
JBrowse link
G Aprt adenine phosphoribosyl transferase increases expression EXP nimesulide results in increased expression of APRT mRNA CTD PMID:24136188 NCBI chr19:50,626,436...50,628,404
Ensembl chr19:50,626,202...50,628,431
JBrowse link
G Aqp8 aquaporin 8 increases expression EXP nimesulide results in increased expression of AQP8 mRNA CTD PMID:24136188 NCBI chr 1:177,993,313...177,999,158
Ensembl chr 1:177,993,305...177,999,158
JBrowse link
G Areg amphiregulin multiple interactions ISO nimesulide inhibits the reaction [LHB results in increased expression of AREG mRNA]; nimesulide inhibits the reaction [LHB results in increased expression of AREG protein] CTD PMID:16888076 NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535
JBrowse link
G Arhgap24 Rho GTPase activating protein 24 decreases expression EXP nimesulide results in decreased expression of ARHGAP24 mRNA CTD PMID:24136188 NCBI chr14:6,800,631...7,184,001
Ensembl chr14:6,800,631...7,183,823
JBrowse link
G Arhgdib Rho GDP dissociation inhibitor beta decreases expression EXP nimesulide results in decreased expression of ARHGDIB mRNA CTD PMID:24136188 NCBI chr 4:169,822,951...169,841,884
Ensembl chr 4:169,822,952...169,841,658
JBrowse link
G Arhgef19 Rho guanine nucleotide exchange factor 19 decreases expression EXP nimesulide results in decreased expression of ARHGEF19 mRNA CTD PMID:24136188 NCBI chr 5:153,536,038...153,554,203
Ensembl chr 5:153,536,013...153,554,203
JBrowse link
G Arpc5l actin related protein 2/3 complex, subunit 5-like increases expression EXP nimesulide results in increased expression of ARPC5L mRNA CTD PMID:24136188 NCBI chr 3:22,758,710...22,767,520
Ensembl chr 3:22,759,876...22,767,538
JBrowse link
G Arpin actin-related protein 2/3 complex inhibitor increases expression EXP nimesulide results in increased expression of ARPIN mRNA CTD PMID:24136188 NCBI chr 1:133,864,288...133,873,124
Ensembl chr 1:133,864,265...133,873,124
JBrowse link
G Arpp19 cAMP-regulated phosphoprotein 19 increases expression EXP nimesulide results in increased expression of ARPP19 mRNA CTD PMID:24136188 NCBI chr 8:75,779,640...75,802,474
Ensembl chr 8:75,779,523...75,802,452
JBrowse link
G Asap2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 decreases expression EXP nimesulide results in decreased expression of ASAP2 mRNA CTD PMID:24136188 NCBI chr 6:40,658,201...40,821,017
Ensembl chr 6:40,657,880...40,820,975
JBrowse link
G Asgr2 asialoglycoprotein receptor 2 decreases expression EXP nimesulide results in decreased expression of ASGR2 mRNA CTD PMID:24136188 NCBI chr10:54,821,407...54,834,624
Ensembl chr10:54,821,438...54,834,617
JBrowse link
G Aspg asparaginase decreases expression EXP nimesulide results in decreased expression of ASPG mRNA CTD PMID:24136188 NCBI chr 6:131,176,727...131,196,268
Ensembl chr 6:131,176,874...131,196,268
JBrowse link
G Atf4 activating transcription factor 4 increases expression EXP nimesulide results in increased expression of ATF4 mRNA CTD PMID:24136188 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
JBrowse link
G Atic 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase increases expression EXP nimesulide results in increased expression of ATIC mRNA CTD PMID:24136188 NCBI chr 9:73,164,846...73,184,897
Ensembl chr 9:73,164,846...73,184,889
JBrowse link
G Atl2 atlastin GTPase 2 increases expression EXP nimesulide results in increased expression of ATL2 mRNA CTD PMID:24136188 NCBI chr 6:15,139,071...15,180,421
Ensembl chr 6:15,139,044...15,180,421
JBrowse link
G Atp1b1 ATPase Na+/K+ transporting subunit beta 1 decreases expression EXP nimesulide results in decreased expression of ATP1B1 mRNA CTD PMID:24136188 NCBI chr13:76,786,580...76,807,096
Ensembl chr13:76,786,578...76,807,459
JBrowse link
G Atp5if1 ATP synthase inhibitory factor subunit 1 increases expression EXP nimesulide results in increased expression of ATPIF1 mRNA CTD PMID:24136188 NCBI chr 5:144,738,950...144,742,668
Ensembl chr 5:144,738,950...144,742,668
JBrowse link
G Atp5mc1 ATP synthase membrane subunit c locus 1 increases expression EXP nimesulide results in increased expression of ATP5MC1 mRNA CTD PMID:24136188 NCBI chr10:81,024,056...81,026,780
Ensembl chr10:81,023,925...81,027,124
Ensembl chr10:81,023,925...81,027,124
JBrowse link
G Atp6ap2 ATPase H+ transporting accessory protein 2 increases expression EXP nimesulide results in increased expression of ATP6AP2 mRNA CTD PMID:24136188 NCBI chr  X:10,183,983...10,210,948
Ensembl chr  X:10,183,068...10,210,918
JBrowse link
G Atp6v0b ATPase H+ transporting V0 subunit B increases expression EXP nimesulide results in increased expression of ATP6V0B mRNA CTD PMID:24136188 NCBI chr 5:131,423,384...131,424,900
Ensembl chr 5:131,423,387...131,426,401
JBrowse link
G Atp6v0e1 ATPase H+ transporting V0 subunit e1 increases expression EXP nimesulide results in increased expression of ATP6V0E1 mRNA CTD PMID:24136188 NCBI chr10:16,479,656...16,502,732
Ensembl chr10:16,479,567...16,524,434
JBrowse link
G Atp6v0e2 ATPase, H+ transporting V0 subunit e2 increases expression EXP nimesulide results in increased expression of ATP6V0E2 mRNA CTD PMID:24136188 NCBI chr 4:77,484,868...77,488,016
Ensembl chr 4:77,482,226...77,488,777
JBrowse link
G Atp6v1f ATPase H+ transporting V1 subunit F increases expression EXP nimesulide results in increased expression of ATP6V1F mRNA CTD PMID:24136188 NCBI chr 4:58,067,666...58,070,628 JBrowse link
G Atp6v1g1 ATPase H+ transporting V1 subunit G1 increases expression EXP nimesulide results in increased expression of ATP6V1G1 mRNA CTD PMID:24136188 NCBI chr 5:76,961,462...76,967,642
Ensembl chr 5:76,961,499...76,969,463
JBrowse link
G Atrn attractin decreases expression EXP nimesulide results in decreased expression of ATRN mRNA CTD PMID:24136188 NCBI chr 3:118,110,320...118,244,326
Ensembl chr 3:118,110,229...118,244,322
JBrowse link
G Aup1 AUP1, lipid droplet regulating VLDL assembly factor increases expression EXP nimesulide results in increased expression of AUP1 mRNA CTD PMID:24136188 NCBI chr 4:115,560,274...115,563,346
Ensembl chr 4:115,560,261...115,563,346
JBrowse link
G Aven apoptosis and caspase activation inhibitor increases expression EXP nimesulide results in increased expression of AVEN mRNA CTD PMID:24136188 NCBI chr 3:99,299,009...99,431,635
Ensembl chr 3:99,298,930...99,431,634
JBrowse link
G Avpr1a arginine vasopressin receptor 1A decreases expression EXP nimesulide results in decreased expression of AVPR1A mRNA CTD PMID:24136188 NCBI chr 7:58,114,306...58,118,230
Ensembl chr 7:58,114,284...58,122,215
JBrowse link
G Axl Axl receptor tyrosine kinase decreases expression EXP nimesulide results in decreased expression of AXL mRNA CTD PMID:24136188 NCBI chr 1:81,265,656...81,296,278
Ensembl chr 1:81,265,088...81,296,265
JBrowse link
G B2m beta-2 microglobulin decreases expression EXP nimesulide results in decreased expression of B2M mRNA CTD PMID:24136188 NCBI chr 3:109,095,740...109,101,764
Ensembl chr 3:109,095,729...109,101,766
JBrowse link
G Bak1 BCL2-antagonist/killer 1 multiple interactions
decreases response to substance
ISO
EXP
nimesulide inhibits the reaction [Etoposide results in increased activity of BAK1 protein]
BAK1 results in decreased susceptibility to nimesulide
CTD PMID:18349538 PMID:21745461 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
JBrowse link
G Banf1 BAF nuclear assembly factor 1 increases expression EXP nimesulide results in increased expression of BANF1 mRNA CTD PMID:24136188 NCBI chr 1:202,672,170...202,674,215
Ensembl chr 1:202,671,305...202,674,188
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO nimesulide inhibits the reaction [Etoposide results in increased activity of and affects the localization of BAX protein] CTD PMID:21745461 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bbox1 gamma-butyrobetaine hydroxylase 1 decreases expression EXP nimesulide results in decreased expression of BBOX1 mRNA CTD PMID:24136188 NCBI chr 3:96,822,654...96,871,786
Ensembl chr 3:96,822,655...96,871,458
JBrowse link
G Bcar1 BCAR1 scaffold protein, Cas family member decreases expression EXP nimesulide results in decreased expression of BCAR1 mRNA CTD PMID:24136188 NCBI chr19:39,679,218...39,713,952
Ensembl chr19:39,679,204...39,713,907
JBrowse link
G Bccip BRCA2 and CDKN1A interacting protein increases expression EXP nimesulide results in increased expression of BCCIP mRNA CTD PMID:24136188 NCBI chr 1:188,512,544...188,524,957
Ensembl chr 1:188,512,367...188,524,958
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
affects localization
ISO
EXP
nimesulide results in decreased expression of BCL2 mRNA; nimesulide results in decreased expression of BCL2 protein
nimesulide affects the localization of BCL2 protein
CTD PMID:18564172 PMID:19772912 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bcs1l BCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone increases expression EXP nimesulide results in increased expression of BCS1L mRNA CTD PMID:24136188 NCBI chr 9:76,164,925...76,168,940
Ensembl chr 9:76,164,932...76,168,938
JBrowse link
G Bdh1 3-hydroxybutyrate dehydrogenase 1 decreases expression EXP nimesulide results in decreased expression of BDH1 mRNA CTD PMID:24136188 NCBI chr11:69,302,534...69,343,173
Ensembl chr11:69,302,534...69,337,671
JBrowse link
G Bet1 Bet1 golgi vesicular membrane trafficking protein increases expression EXP nimesulide results in increased expression of BET1 mRNA CTD PMID:24136188 NCBI chr 4:32,116,232...32,126,592
Ensembl chr 4:32,116,235...32,126,617
JBrowse link
G Bgn biglycan decreases expression EXP nimesulide results in decreased expression of BGN mRNA CTD PMID:24136188 NCBI chr  X:151,197,296...151,209,458
Ensembl chr  X:151,197,273...151,209,461
JBrowse link
G Bhlhe40 basic helix-loop-helix family, member e40 decreases expression EXP nimesulide results in decreased expression of BHLHE40 mRNA CTD PMID:24136188 NCBI chr 4:141,618,453...141,624,154
Ensembl chr 4:141,618,476...141,624,774
JBrowse link
G Bhmt betaine-homocysteine S-methyltransferase decreases expression EXP nimesulide results in decreased expression of BHMT mRNA CTD PMID:24136188 NCBI chr 2:24,859,871...24,879,449
Ensembl chr 2:24,859,873...24,879,742
JBrowse link
G Bhmt2 betaine-homocysteine S-methyltransferase 2 decreases expression EXP nimesulide results in decreased expression of BHMT2 mRNA CTD PMID:24136188 NCBI chr 2:24,895,525...24,912,475
Ensembl chr 2:24,895,533...24,912,475
JBrowse link
G Bid BH3 interacting domain death agonist multiple interactions ISO benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [nimesulide results in increased cleavage of and results in increased activity of BID protein]; nimesulide results in increased cleavage of and results in increased activity of BID protein CTD PMID:19360361 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases expression
decreases expression
ISO nimesulide results in decreased expression of BIRC5 protein
Nimesulide decreases expression of BIRC5 protein in esophagus squamous epithelium
CTD PMID:16969492 PMID:25724470 RGD:127285656 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
JBrowse link
G Blvrb biliverdin reductase B increases expression EXP nimesulide results in increased expression of BLVRB mRNA CTD PMID:24136188 NCBI chr 1:82,738,646...82,756,312
Ensembl chr 1:82,738,695...82,770,375
JBrowse link
G Bmp1 bone morphogenetic protein 1 decreases expression EXP nimesulide results in decreased expression of BMP1 mRNA CTD PMID:24136188 NCBI chr15:45,551,603...45,595,862
Ensembl chr15:45,551,603...45,595,776
JBrowse link
G Bmp6 bone morphogenetic protein 6 increases expression ISO nimesulide results in increased expression of BMP6 mRNA CTD PMID:32816093 NCBI chr17:26,318,121...26,469,034
Ensembl chr17:26,318,569...26,470,365
JBrowse link
G Bnip3 BCL2 interacting protein 3 increases expression EXP nimesulide results in increased expression of BNIP3 mRNA CTD PMID:24136188 NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359
JBrowse link
G Bnip3l BCL2 interacting protein 3 like increases expression EXP nimesulide results in increased expression of BNIP3L mRNA CTD PMID:24136188 NCBI chr15:41,174,594...41,197,730
Ensembl chr15:41,174,594...41,197,803
JBrowse link
G Bola1 bolA family member 1 increases expression EXP nimesulide results in increased expression of BOLA1 mRNA CTD PMID:24136188 NCBI chr 2:183,758,515...183,771,445
Ensembl chr 2:183,758,441...183,781,576
JBrowse link
G Bola3 bolA family member 3 increases expression EXP nimesulide results in increased expression of BOLA3 mRNA CTD PMID:24136188 NCBI chr 4:115,853,350...115,862,797
Ensembl chr 4:115,853,350...115,862,797
JBrowse link
G Bop1 BOP1 ribosomal biogenesis factor increases expression EXP nimesulide results in increased expression of BOP1 mRNA CTD PMID:24136188 NCBI chr 7:108,172,062...108,195,875
Ensembl chr 7:108,172,066...108,195,931
JBrowse link
G Btg1 BTG anti-proliferation factor 1 decreases expression EXP nimesulide results in decreased expression of BTG1 mRNA CTD PMID:24136188 NCBI chr 7:31,341,391...31,343,649
Ensembl chr 7:31,341,027...31,343,649
JBrowse link
G Bysl bystin-like increases expression EXP nimesulide results in increased expression of BYSL mRNA CTD PMID:24136188 NCBI chr 9:13,382,806...13,392,557
Ensembl chr 9:13,382,557...13,394,339
JBrowse link
G C1galt1c1 C1GALT1-specific chaperone 1 increases expression EXP nimesulide results in increased expression of C1GALT1C1 mRNA CTD PMID:24136188 NCBI chr  X:117,378,123...117,382,620
Ensembl chr  X:117,375,525...117,382,787
JBrowse link
G C1qa complement C1q A chain decreases expression EXP nimesulide results in decreased expression of C1QA mRNA CTD PMID:24136188 NCBI chr 5:149,133,635...149,136,482
Ensembl chr 5:149,133,636...149,136,534
JBrowse link
G C1qb complement C1q B chain multiple interactions
decreases expression
ISO
EXP
nimesulide inhibits the reaction [PTGS2 results in increased expression of C1QB mRNA]
nimesulide results in decreased expression of C1QB mRNA
CTD PMID:11810182 PMID:24136188 NCBI chr 5:149,118,843...149,124,394
Ensembl chr 5:149,118,846...149,124,407
JBrowse link
G C1qbp complement C1q binding protein increases expression EXP nimesulide results in increased expression of C1QBP mRNA CTD PMID:24136188 NCBI chr10:55,699,954...55,704,605
Ensembl chr10:55,699,954...55,704,649
JBrowse link
G C1qc complement C1q C chain decreases expression EXP nimesulide results in decreased expression of C1QC mRNA CTD PMID:24136188 NCBI chr 5:149,127,424...149,130,732
Ensembl chr 5:149,127,415...149,131,017
JBrowse link
G C1s complement C1s decreases expression EXP nimesulide results in decreased expression of C1S mRNA CTD PMID:24136188 NCBI chr 4:157,430,249...157,442,438
Ensembl chr 4:157,430,117...157,442,303
JBrowse link
G C6 complement C6 decreases expression EXP nimesulide results in decreased expression of C6 mRNA CTD PMID:24136188 NCBI chr 2:53,846,027...53,921,279
Ensembl chr 2:53,851,985...53,921,275
JBrowse link
G C8a complement C8 alpha chain decreases expression EXP nimesulide results in decreased expression of C8A mRNA CTD PMID:24136188 NCBI chr 5:119,583,168...119,637,675
Ensembl chr 5:119,583,174...119,637,754
JBrowse link
G C8b complement C8 beta chain decreases expression EXP nimesulide results in decreased expression of C8B mRNA CTD PMID:24136188 NCBI chr 5:119,535,009...119,572,565
Ensembl chr 5:119,535,146...119,572,565
JBrowse link
G C9 complement C9 decreases expression EXP nimesulide results in decreased expression of C9 mRNA CTD PMID:24136188 NCBI chr 2:55,573,094...55,621,345
Ensembl chr 2:55,572,992...55,621,338
JBrowse link
G Ca3 carbonic anhydrase 3 decreases expression EXP nimesulide results in decreased expression of CAR3 mRNA CTD PMID:24136188 NCBI chr 2:86,770,418...86,780,011
Ensembl chr 2:86,770,420...86,784,280
JBrowse link
G Ca8 carbonic anhydrase 8 increases expression EXP nimesulide results in increased expression of CAR8 mRNA CTD PMID:24136188 NCBI chr 5:21,302,940...21,402,395
Ensembl chr 5:21,305,383...21,402,374
JBrowse link
G Cacybp calcyclin binding protein increases expression EXP nimesulide results in increased expression of CACYBP mRNA CTD PMID:24136188 NCBI chr13:72,437,485...72,447,810
Ensembl chr13:72,437,490...72,450,177
JBrowse link
G Calm2 calmodulin 2 decreases expression EXP nimesulide results in decreased expression of CALM2 mRNA CTD PMID:24136188 NCBI chr 6:7,091,624...7,104,284
Ensembl chr 6:7,091,567...7,104,287
JBrowse link
G Canx calnexin increases expression EXP nimesulide results in increased expression of CANX mRNA CTD PMID:24136188 NCBI chr10:34,623,865...34,656,866
Ensembl chr10:34,625,191...34,656,821
JBrowse link
G Cap1 cyclase associated actin cytoskeleton regulatory protein 1 decreases expression EXP nimesulide results in decreased expression of CAP1 mRNA CTD PMID:24136188 NCBI chr 5:135,142,108...135,168,885
Ensembl chr 5:135,142,112...135,168,769
JBrowse link
G Capn2 calpain 2 decreases expression EXP nimesulide results in decreased expression of CAPN2 mRNA CTD PMID:24136188 NCBI chr13:94,150,244...94,200,969
Ensembl chr13:94,150,240...94,200,969
JBrowse link
G Carhsp1 calcium regulated heat stable protein 1 decreases expression EXP nimesulide results in decreased expression of CARHSP1 mRNA CTD PMID:24136188 NCBI chr10:6,946,036...6,960,556
Ensembl chr10:6,946,959...7,020,019
JBrowse link
G Casp3 caspase 3 multiple interactions
increases expression
increases cleavage
increases activity
ISO
EXP
benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [nimesulide results in increased cleavage of and results in increased activity of CASP3 protein]; nimesulide inhibits the reaction [Etoposide results in increased cleavage of CASP3 protein]; nimesulide results in increased cleavage of and results in increased activity of CASP3 protein
Nimesulide increases expression of CASP3 protein in esophagus squamous epithelium
nimesulide results in increased cleavage of CASP3 protein
nimesulide results in increased expression of CASP3 mRNA
nimesulide results in increased activity of CASP3 protein
[camphene co-treated with geraniol] inhibits the reaction [nimesulide results in increased cleavage of CASP3 protein]; nimesulide inhibits the reaction [Staurosporine results in increased activity of CASP3 protein]; Silymarin inhibits the reaction [nimesulide results in increased cleavage of CASP3 protein]
nimesulide results in increased expression of CASP3 mRNA; nimesulide results in increased expression of CASP3 protein
CTD PMID:11296547 PMID:19360361 PMID:19772912 PMID:21176579 PMID:21745461 More... RGD:127285656 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp8 caspase 8 multiple interactions ISO benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [nimesulide results in increased cleavage of and results in increased activity of CASP8 protein]; nimesulide inhibits the reaction [Etoposide results in increased cleavage of and results in increased activity of CASP8 protein]; nimesulide results in increased activity of and results in increased cleavage of CASP8 protein CTD PMID:19360361 PMID:21745461 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 multiple interactions
increases cleavage
increases activity
ISO
EXP
benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [nimesulide results in increased cleavage of and results in increased activity of CASP9 protein]; nimesulide inhibits the reaction [Etoposide results in increased cleavage of and results in increased activity of CASP9 protein]; nimesulide results in increased cleavage of and results in increased activity of CASP9 protein
nimesulide results in increased cleavage of CASP9 protein
[camphene co-treated with geraniol] inhibits the reaction [nimesulide results in increased cleavage of CASP9 protein]; Silymarin inhibits the reaction [nimesulide results in increased cleavage of CASP9 protein]
nimesulide results in increased activity of CASP9 protein
CTD PMID:19360361 PMID:19772912 PMID:21745461 PMID:22509279 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cat catalase decreases expression
decreases activity
multiple interactions
ISO
EXP
nimesulide results in decreased expression of CAT protein
nimesulide results in decreased activity of CAT; nimesulide results in decreased activity of CAT protein
nimesulide inhibits the reaction [Quinolinic Acid results in decreased expression of CAT protein]
CTD PMID:17147060 PMID:17274466 PMID:18848576 PMID:20043943 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cav1 caveolin 1 increases expression ISO nimesulide results in increased expression of CAV1 protein CTD PMID:18848576 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
JBrowse link
G Cavin3 caveolae associated protein 3 increases expression EXP n