Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:inorganic nitrate salt
go back to main search page
Accession:CHEBI:51084 term browser browse the term
Synonyms:related_synonym: inorganic nitrate salts;   inorganic nitrates


show annotations for term's descendants           Sort by:
 
ammonium nitrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il1b interleukin 1 beta increases expression ISO ammonium nitrate results in increased expression of IL1B protein CTD PMID:29953848 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
cadmium nitrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cav1 caveolin 1 decreases expression ISO cadmium nitrate results in decreased expression of CAV1 protein CTD PMID:19061949 NCBI chr 4:44,597,123...44,630,206
Ensembl chr 4:44,597,123...44,630,200
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase decreases activity EXP cadmium nitrate results in decreased activity of G6PD protein CTD PMID:28557068 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926
JBrowse link
G Itgb4 integrin subunit beta 4 decreases expression ISO cadmium nitrate results in decreased expression of ITGB4 protein CTD PMID:19061949 NCBI chr10:104,524,000...104,560,180
Ensembl chr10:104,523,996...104,561,078
JBrowse link
chromium trinitrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahsg alpha-2-HS-glycoprotein decreases expression ISO chromium nitrate results in decreased expression of AHSG protein CTD PMID:23618972 NCBI chr11:81,711,269...81,717,594 JBrowse link
G Aldh1l2 aldehyde dehydrogenase 1 family, member L2 increases expression ISO chromium nitrate results in increased expression of ALDH1L2 protein CTD PMID:22144121 NCBI chr 7:26,375,866...26,425,838
Ensembl chr 7:26,375,866...26,425,108
JBrowse link
G Apcs amyloid P component, serum increases expression ISO chromium nitrate results in increased expression of APCS protein CTD PMID:23618972 NCBI chr13:91,426,621...91,427,417
Ensembl chr13:91,426,479...91,427,575
JBrowse link
G Apoa1 apolipoprotein A1 decreases expression ISO chromium nitrate results in decreased expression of APOA1 protein CTD PMID:23618972 NCBI chr 8:50,525,091...50,526,875
Ensembl chr 8:50,525,091...50,526,875
JBrowse link
G Atp5f1b ATP synthase F1 subunit beta increases expression ISO chromium nitrate results in increased expression of ATP5B protein CTD PMID:19771553 NCBI chr 7:2,504,708...2,511,748
Ensembl chr 7:2,504,695...2,511,749
JBrowse link
G Bckdhb branched chain keto acid dehydrogenase E1 subunit beta decreases expression ISO chromium nitrate results in decreased expression of BCKDHB protein CTD PMID:22144121 NCBI chr 8:91,464,229...91,656,134
Ensembl chr 8:91,464,229...91,656,134
JBrowse link
G Cct5 chaperonin containing TCP1 subunit 5 decreases expression ISO chromium nitrate results in decreased expression of CCT5 protein CTD PMID:22144121 NCBI chr 2:84,667,578...84,678,730
Ensembl chr 2:84,667,633...84,678,790
JBrowse link
G Ces1d carboxylesterase 1D increases expression ISO chromium nitrate results in increased expression of CES1D protein CTD PMID:22144121 NCBI chr19:15,195,514...15,239,827
Ensembl chr19:15,033,108...15,239,821
JBrowse link
G Dbt dihydrolipoamide branched chain transacylase E2 increases expression ISO chromium nitrate results in increased expression of DBT protein CTD PMID:22144121 NCBI chr 2:219,563,783...219,592,651
Ensembl chr 2:219,563,783...219,592,650
JBrowse link
G Ddah1 dimethylarginine dimethylaminohydrolase 1 decreases expression ISO chromium nitrate results in decreased expression of DDAH1 protein CTD PMID:22144121 NCBI chr 2:251,634,368...251,766,009
Ensembl chr 2:251,634,431...251,766,014
JBrowse link
G Ech1 enoyl-CoA hydratase 1 increases expression ISO chromium nitrate results in increased expression of ECH1 protein CTD PMID:22144121 NCBI chr 1:87,009,798...87,015,996
Ensembl chr 1:87,009,730...87,016,005
JBrowse link
G Fbp1 fructose-bisphosphatase 1 increases expression ISO chromium nitrate results in increased expression of FBP1 protein CTD PMID:22144121 NCBI chr17:396,175...417,480
Ensembl chr17:396,180...417,480
JBrowse link
G Fgb fibrinogen beta chain increases expression ISO chromium nitrate results in increased expression of FGB protein CTD PMID:23618972 NCBI chr 2:182,028,044...182,035,026
Ensembl chr 2:182,027,115...182,038,178
JBrowse link
G Fgg fibrinogen gamma chain increases expression ISO chromium nitrate results in increased expression of FGG protein CTD PMID:23618972 NCBI chr 2:181,987,080...181,994,523
Ensembl chr 2:181,987,217...181,994,514
JBrowse link
G Fkrp fukutin related protein increases expression ISO chromium nitrate results in increased expression of FKRP protein CTD PMID:23618972 NCBI chr 1:78,733,461...78,740,803
Ensembl chr 1:78,733,508...78,739,107
JBrowse link
G Gc GC, vitamin D binding protein decreases expression ISO chromium nitrate results in decreased expression of GC protein CTD PMID:23618972 NCBI chr14:20,267,023...20,302,577
Ensembl chr14:20,266,891...20,302,581
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression ISO chromium nitrate results in increased expression of GCLC mRNA CTD PMID:20491607 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Haao 3-hydroxyanthranilate 3,4-dioxygenase increases expression ISO chromium nitrate results in increased expression of HAAO protein CTD PMID:22144121 NCBI chr 6:7,045,145...7,059,227
Ensembl chr 6:7,045,152...7,058,314
JBrowse link
G Hacl1 2-hydroxyacyl-CoA lyase 1 increases expression ISO chromium nitrate results in increased expression of HACL1 protein CTD PMID:22144121 NCBI chr16:7,720,047...7,758,119
Ensembl chr16:7,714,465...7,758,189
JBrowse link
G Hibadh 3-hydroxyisobutyrate dehydrogenase increases expression ISO chromium nitrate results in increased expression of HIBADH protein CTD PMID:22144121 NCBI chr 4:82,604,369...82,702,429
Ensembl chr 4:82,604,373...82,702,429
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO chromium nitrate results in increased expression of HMOX1 mRNA CTD PMID:20491607 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 increases expression ISO chromium nitrate results in increased expression of HSPD1 protein CTD PMID:19771553 NCBI chr 9:61,680,529...61,691,202
Ensembl chr 9:61,680,530...61,690,956
JBrowse link
G Khk ketohexokinase decreases expression ISO chromium nitrate results in decreased expression of KHK protein CTD PMID:22144121 NCBI chr 6:26,810,577...26,821,013
Ensembl chr 6:26,810,579...26,820,959
JBrowse link
G Kng2 kininogen 2 increases expression ISO chromium nitrate results in increased expression of KNG1 protein CTD PMID:23618972 NCBI chr11:81,509,185...81,516,759 JBrowse link
G Krt10 keratin 10 increases expression ISO chromium nitrate results in increased expression of KRT10 protein CTD PMID:19771553 NCBI chr10:87,296,445...87,301,307
Ensembl chr10:87,296,451...87,300,736
JBrowse link
G Krt16 keratin 16 increases expression ISO chromium nitrate results in increased expression of KRT16 protein CTD PMID:19771553 NCBI chr10:88,149,210...88,152,167
Ensembl chr10:88,149,345...88,152,064
JBrowse link
G Krt17 keratin 17 increases expression ISO chromium nitrate results in increased expression of KRT17 protein CTD PMID:19771553 NCBI chr10:88,158,993...88,163,712
Ensembl chr10:88,118,001...88,163,723
JBrowse link
G Krt18 keratin 18 decreases expression ISO chromium nitrate results in decreased expression of KRT18 protein CTD PMID:22144121 NCBI chr 7:143,629,455...143,633,131
Ensembl chr 7:143,629,455...143,633,131
JBrowse link
G Krt25 keratin 25 increases expression ISO chromium nitrate results in increased expression of KRT25 protein CTD PMID:19771553 NCBI chr10:87,225,361...87,238,659
Ensembl chr10:87,225,343...87,232,723
JBrowse link
G Krt27 keratin 27 increases expression ISO chromium nitrate results in increased expression of KRT27 protein CTD PMID:19771553 NCBI chr10:87,256,434...87,261,717
Ensembl chr10:87,256,434...87,261,717
JBrowse link
G Mdh1 malate dehydrogenase 1 increases expression ISO chromium nitrate results in increased expression of MDH1 protein CTD PMID:22144121 NCBI chr14:106,378,349...106,393,642
Ensembl chr14:106,378,942...106,393,670
JBrowse link
G Mt2A metallothionein 2A increases expression ISO chromium nitrate results in increased expression of MT2A mRNA CTD PMID:20491607 NCBI chr19:11,307,966...11,308,740
Ensembl chr19:11,307,967...11,308,740
JBrowse link
G Park7 Parkinsonism associated deglycase increases expression ISO chromium nitrate results in increased expression of PARK7 protein CTD PMID:22144121 NCBI chr 5:167,982,438...168,004,724
Ensembl chr 5:167,982,439...168,004,724
JBrowse link
G Pcca propionyl-CoA carboxylase subunit alpha increases expression ISO chromium nitrate results in increased expression of PCCA protein CTD PMID:22144121 NCBI chr15:108,960,509...109,306,879
Ensembl chr15:108,960,562...109,306,603
JBrowse link
G Pdhb pyruvate dehydrogenase E1 subunit beta decreases expression ISO chromium nitrate results in decreased expression of PDHB protein CTD PMID:22144121 NCBI chr15:18,540,826...18,546,855
Ensembl chr15:18,539,210...18,546,854
JBrowse link
G Phb prohibitin decreases expression ISO chromium nitrate results in decreased expression of PHB protein CTD PMID:22144121 NCBI chr10:83,476,107...83,488,878
Ensembl chr10:83,476,107...83,488,878
JBrowse link
G Rgn regucalcin decreases expression ISO chromium nitrate results in decreased expression of RGN protein CTD PMID:22144121 NCBI chr  X:1,833,484...1,848,904
Ensembl chr  X:1,833,492...1,848,904
JBrowse link
G Rplp0 ribosomal protein lateral stalk subunit P0 decreases expression ISO chromium nitrate results in decreased expression of RPLP0 protein CTD PMID:22144121 NCBI chr12:46,791,528...46,794,797
Ensembl chr12:46,791,528...46,794,797
JBrowse link
G Serpinc1 serpin family C member 1 decreases expression ISO chromium nitrate results in decreased expression of SERPINC1 protein CTD PMID:23618972 NCBI chr13:78,806,107...78,820,375
Ensembl chr13:78,805,347...78,833,192
JBrowse link
G Suclg2 succinate-CoA ligase GDP-forming subunit beta decreases expression ISO chromium nitrate results in decreased expression of SUCLG2 protein CTD PMID:22144121 NCBI chr 4:127,552,100...127,824,970
Ensembl chr 4:127,552,101...127,824,970
JBrowse link
G Tkfc triokinase and FMN cyclase increases expression ISO chromium nitrate results in increased expression of TKFC protein CTD PMID:22144121 NCBI chr 1:226,642,901...226,657,698
Ensembl chr 1:226,644,200...226,657,408
JBrowse link
G Uqcrc1 ubiquinol-cytochrome c reductase core protein 1 decreases expression ISO chromium nitrate results in decreased expression of UQCRC1 protein CTD PMID:22144121 NCBI chr 8:117,679,328...117,691,073
Ensembl chr 8:117,679,278...117,691,071
JBrowse link
G Vcp valosin-containing protein decreases expression ISO chromium nitrate results in decreased expression of VCP protein CTD PMID:22144121 NCBI chr 5:58,426,548...58,445,953
Ensembl chr 5:58,426,549...58,445,953
JBrowse link
copper(II) nitrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor multiple interactions ISO [copper(II) nitrate binds to 1,10-phenanthroline binds to Quinolones] which results in increased activity of AHR protein; [copper(II) nitrate binds to 5-methyl-1,10-phenanthroline binds to Quinolones] which results in increased activity of AHR protein; resveratrol inhibits the reaction [[copper(II) nitrate binds to 1,10-phenanthroline binds to Quinolones] which results in increased activity of AHR protein]; resveratrol inhibits the reaction [[copper(II) nitrate binds to 5-methyl-1,10-phenanthroline binds to Quinolones] which results in increased activity of AHR protein] CTD PMID:27180721 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO [copper(II) nitrate binds to 1,10-phenanthroline binds to Quinolones] which results in increased expression of CYP1A1 mRNA; [copper(II) nitrate binds to 5-methyl-1,10-phenanthroline binds to Quinolones] which results in increased expression of CYP1A1 mRNA; [copper(II) nitrate binds to bathophenanthroline binds to Quinolones] which results in increased expression of CYP1A1 mRNA CTD PMID:27180721 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Il2 interleukin 2 decreases secretion ISO copper(II) nitrate results in decreased secretion of IL2 protein CTD PMID:27714827 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
JBrowse link
lead nitrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aco1 aconitase 1 decreases expression
multiple interactions
ISO lead nitrate results in decreased expression of ACO1 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [lead nitrate results in decreased expression of ACO1 protein]
CTD PMID:22502979 NCBI chr 5:56,425,076...56,481,218
Ensembl chr 5:56,425,024...56,481,218
JBrowse link
G Acta1 actin, alpha 1, skeletal muscle increases expression ISO lead nitrate results in increased expression of ACTA1 protein CTD PMID:20435106 NCBI chr19:56,674,072...56,677,084
Ensembl chr19:56,674,074...56,677,084
JBrowse link
G Akap3 A-kinase anchoring protein 3 decreases expression EXP lead nitrate results in decreased expression of AKAP3 mRNA CTD PMID:21628963 NCBI chr 4:159,399,686...159,425,512
Ensembl chr 4:159,403,501...159,425,629
JBrowse link
G Alad aminolevulinate dehydratase multiple interactions
decreases activity
ISO lead nitrate inhibits the reaction [Dithiothreitol results in increased activity of ALAD protein]; lead nitrate inhibits the reaction [zinc chloride promotes the reaction [Dithiothreitol results in increased activity of ALAD protein]]
lead nitrate results in decreased activity of ALAD protein
CTD PMID:2061546 NCBI chr 5:78,368,867...78,379,206
Ensembl chr 5:78,368,867...78,379,346
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 decreases expression
multiple interactions
ISO lead nitrate results in decreased expression of APAF1 protein
mangiferin inhibits the reaction [lead nitrate results in decreased expression of APAF1 protein]
CTD PMID:23451106 NCBI chr 7:31,699,309...31,784,192
Ensembl chr 7:31,699,885...31,784,192
JBrowse link
G Arhgdib Rho GDP dissociation inhibitor beta increases expression ISO lead nitrate results in increased expression of ARHGDIB protein CTD PMID:20435106 NCBI chr 4:170,913,920...170,932,789
Ensembl chr 4:170,913,923...170,932,618
JBrowse link
G Arrdc5 arrestin domain containing 5 decreases expression EXP lead nitrate results in decreased expression of ARRDC5 mRNA CTD PMID:21628963 NCBI chr 9:10,760,113...10,766,199
Ensembl chr 9:10,760,113...10,766,199
JBrowse link
G Azin2 antizyme inhibitor 2 decreases expression EXP lead nitrate results in decreased expression of AZIN2 mRNA CTD PMID:21628963 NCBI chr 5:147,120,128...147,148,576
Ensembl chr 5:147,120,129...147,148,291
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
increases expression
ISO mangiferin inhibits the reaction [lead nitrate results in increased expression of BAX protein]
[lead nitrate results in increased abundance of Lead] which results in increased expression of BAX mRNA; titanium dioxide inhibits the reaction [[lead nitrate results in increased abundance of Lead] which results in decreased expression of BAX mRNA]; titanium dioxide inhibits the reaction [[lead nitrate results in increased abundance of Lead] which results in increased expression of BAX mRNA]
CTD PMID:23451106, PMID:30738203 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
multiple interactions
ISO lead nitrate results in decreased expression of BCL2 protein
[lead nitrate results in increased abundance of Lead] which results in decreased expression of BCL2 mRNA
mangiferin inhibits the reaction [lead nitrate results in decreased expression of BCL2 protein]
CTD PMID:23451106, PMID:30738203 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Casp3 caspase 3 increases expression
multiple interactions
increases activity
ISO
EXP
lead nitrate results in increased expression of CASP3 protein
[lead nitrate results in increased abundance of Lead] which results in increased activity of CASP3 protein; [lead nitrate results in increased abundance of Lead] which results in increased expression of CASP3 mRNA; titanium dioxide inhibits the reaction [[lead nitrate results in increased abundance of Lead] which results in increased activity of CASP3 protein]; titanium dioxide inhibits the reaction [[lead nitrate results in increased abundance of Lead] which results in increased expression of CASP3 mRNA]
puerarin inhibits the reaction [lead nitrate results in increased activity of CASP3 protein]
mangiferin inhibits the reaction [lead nitrate results in increased expression of CASP3 protein]
CTD PMID:23451106, PMID:24505050, PMID:30738203 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp7 caspase 7 multiple interactions
decreases expression
ISO lead nitrate affects the reaction [CASP7 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [CASP7 affects the expression of MT2 mRNA]
lead nitrate results in decreased expression of CASP7 mRNA
CTD PMID:11891201 NCBI chr 1:277,190,557...277,242,779
Ensembl chr 1:277,190,964...277,242,774
JBrowse link
G Casp9 caspase 9 multiple interactions
increases expression
ISO mangiferin inhibits the reaction [lead nitrate results in increased expression of CASP9 protein]
[lead nitrate results in increased abundance of Lead] which results in increased activity of CASP9 protein; [lead nitrate results in increased abundance of Lead] which results in increased expression of CASP9 mRNA; titanium dioxide inhibits the reaction [[lead nitrate results in increased abundance of Lead] which results in increased activity of CASP9 protein]; titanium dioxide inhibits the reaction [[lead nitrate results in increased abundance of Lead] which results in increased expression of CASP9 mRNA]
CTD PMID:23451106, PMID:30738203 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cat catalase decreases activity
multiple interactions
ISO
EXP
lead nitrate results in decreased activity of CAT protein
[lead nitrate results in increased abundance of Lead] which results in decreased activity of CAT protein; titanium dioxide inhibits the reaction [[lead nitrate results in increased abundance of Lead] which results in decreased activity of CAT protein]
Ashwagandha inhibits the reaction [lead nitrate results in decreased activity of CAT protein]; puerarin inhibits the reaction [lead nitrate results in decreased activity of CAT protein]
mangiferin inhibits the reaction [lead nitrate results in decreased activity of CAT protein]
CTD PMID:23315276, PMID:23451106, PMID:24987671, PMID:30738203 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Ccng1 cyclin G1 multiple interactions ISO lead nitrate affects the reaction [CCNG1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [CCNG1 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr10:25,903,925...25,910,298
Ensembl chr10:25,903,911...25,910,325
JBrowse link
G Cd86 CD86 molecule increases expression ISO lead nitrate results in increased expression of CD86 protein CTD PMID:23376802 NCBI chr11:67,060,305...67,117,990
Ensembl chr11:67,082,193...67,118,795
JBrowse link
G Cdyl chromodomain Y-like decreases expression EXP lead nitrate results in decreased expression of CDYL mRNA CTD PMID:21628963 NCBI chr17:29,672,925...29,895,416
Ensembl chr17:29,674,164...29,895,386
JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex increases phosphorylation
multiple interactions
ISO lead nitrate results in increased phosphorylation of CHUK protein
mangiferin inhibits the reaction [lead nitrate results in increased phosphorylation of CHUK protein]
CTD PMID:23451106 NCBI chr 1:263,848,829...263,884,354
Ensembl chr 1:263,848,884...263,885,169
JBrowse link
G Cox8c cytochrome c oxidase subunit 8C decreases expression EXP lead nitrate results in decreased expression of COX8C mRNA CTD PMID:21628963 NCBI chr 6:126,766,967...126,768,290
Ensembl chr 6:126,766,967...126,768,290
JBrowse link
G Crisp2 cysteine-rich secretory protein 2 decreases expression EXP lead nitrate results in decreased expression of CRISP2 mRNA CTD PMID:21628963 NCBI chr 9:23,503,223...23,527,502
Ensembl chr 9:23,503,236...23,527,496
JBrowse link
G Cryaa crystallin, alpha A affects metabolic processing EXP lead nitrate affects the metabolism of CRYAA protein CTD PMID:21139692 NCBI chr20:10,438,444...10,442,189
Ensembl chr20:10,438,444...10,442,187
JBrowse link
G Cryab crystallin, alpha B affects metabolic processing EXP lead nitrate affects the metabolism of CRYAB protein CTD PMID:21139692 NCBI chr 8:55,178,543...55,182,546
Ensembl chr 8:55,178,289...55,182,545
JBrowse link
G Cst8 cystatin 8 decreases expression EXP lead nitrate results in decreased expression of CST8 mRNA CTD PMID:21628963 NCBI chr 3:143,129,240...143,141,000
Ensembl chr 3:143,129,248...143,156,177
JBrowse link
G Ctnna1 catenin alpha 1 multiple interactions ISO lead nitrate affects the reaction [CTNNA1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [CTNNA1 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr18:27,923,229...28,055,972
Ensembl chr18:27,923,572...28,055,960
JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions ISO [lead nitrate results in increased abundance of Lead] which results in decreased expression of and affects the localization of CTNNB1 protein; [lead nitrate results in increased abundance of Lead] which results in decreased expression of CTNNB1 mRNA; icaritin inhibits the reaction [[lead nitrate results in increased abundance of Lead] which results in decreased expression of and affects the localization of CTNNB1 protein]; icaritin inhibits the reaction [[lead nitrate results in increased abundance of Lead] which results in decreased expression of CTNNB1 mRNA] CTD PMID:30731080 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
JBrowse link
G Cux2 cut-like homeobox 2 multiple interactions ISO lead nitrate affects the reaction [CUX2 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [CUX2 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr12:40,016,774...40,221,067
Ensembl chr12:40,018,937...40,219,291
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases expression
ISO
EXP
lead nitrate inhibits the reaction [1,2,5,6-dibenzanthracene results in increased activity of CYP1A1 protein]; lead nitrate inhibits the reaction [benz(a)anthracene results in increased activity of CYP1A1 protein]; lead nitrate inhibits the reaction [Benzo(a)pyrene results in increased activity of CYP1A1 protein]; lead nitrate inhibits the reaction [benzo(b)fluoranthene results in increased activity of CYP1A1 protein]; lead nitrate inhibits the reaction [benzo(k)fluoranthene results in increased activity of CYP1A1 protein]; lead nitrate inhibits the reaction [benzo(k)fluoranthene results in increased expression of CYP1A1 protein]; lead nitrate inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of CYP1A1 protein]; lead nitrate promotes the reaction [benzo(k)fluoranthene results in increased expression of CYP1A1 protein]
lead nitrate inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CYP1A1 protein]; lead nitrate inhibits the reaction [2-amino-3-methyl-9H-pyrido(2,3-b)indole results in increased expression of CYP1A1 mRNA]; lead nitrate inhibits the reaction [2-amino-3-methyl-9H-pyrido(2,3-b)indole results in increased expression of CYP1A1 protein]; lead nitrate inhibits the reaction [2-methoxy-4-aminoazobenzene results in increased expression of CYP1A1 protein]; lead nitrate inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 protein]; lead nitrate inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 protein]; lead nitrate inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 protein]; Resveratrol inhibits the reaction [lead nitrate results in increased expression of CYP1A1 mRNA]
lead nitrate results in increased expression of CYP1A1 mRNA; lead nitrate results in increased expression of CYP1A1 protein
CTD PMID:8902619, PMID:11162773, PMID:11408366, PMID:17889500, PMID:23391631 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases activity
multiple interactions
ISO
EXP
lead nitrate results in decreased activity of CYP1A2 protein
lead nitrate inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CYP1A2 mRNA]; lead nitrate inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CYP1A2 protein]; lead nitrate inhibits the reaction [2-amino-3-methyl-9H-pyrido(2,3-b)indole results in increased expression of CYP1A2 mRNA]; lead nitrate inhibits the reaction [2-amino-3-methyl-9H-pyrido(2,3-b)indole results in increased expression of CYP1A2 protein]; lead nitrate inhibits the reaction [2-methoxy-4-aminoazobenzene results in increased expression of CYP1A2 mRNA]; lead nitrate inhibits the reaction [2-methoxy-4-aminoazobenzene results in increased expression of CYP1A2 protein]; lead nitrate inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 protein]; lead nitrate inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A2 protein]; lead nitrate inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A2 protein]; lead nitrate results in decreased expression of and results in decreased activity of CYP1A2 protein
CTD PMID:8902619, PMID:11162773 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 increases expression EXP lead nitrate results in increased expression of CYP2C11 mRNA CTD PMID:23391631 NCBI chr 1:257,676,172...258,004,428
Ensembl chr 1:257,970,345...258,004,434
JBrowse link
G Cyp2j3 cytochrome P450, family 2, subfamily j, polypeptide 3 increases expression EXP lead nitrate results in increased expression of CYP2J3 mRNA CTD PMID:23391631 NCBI chr 5:115,196,982...115,222,084 JBrowse link
G Cyp4a1 cytochrome P450, family 4, subfamily a, polypeptide 1 increases expression EXP lead nitrate results in increased expression of CYP4A1 mRNA CTD PMID:23391631 NCBI chr 5:134,492,734...134,507,158
Ensembl chr 5:134,492,756...134,507,154
JBrowse link
G Cyp4f4 cytochrome P450, family 4, subfamily f, polypeptide 4 increases expression EXP lead nitrate results in increased expression of CYP4F4 mRNA CTD PMID:23391631 NCBI chr 7:14,891,062...14,907,250
Ensembl chr 7:14,891,001...14,907,305
JBrowse link
G Cyp51 cytochrome P450, family 51 increases expression
multiple interactions
ISO
EXP
lead nitrate results in increased expression of CYP51 mRNA
[IL1A gene mutant form co-treated with IL1B gene mutant form] inhibits the reaction [lead nitrate results in increased expression of CYP51 mRNA]
CTD PMID:15475176, PMID:22293356 NCBI chr 4:27,175,564...27,194,018
Ensembl chr 4:27,175,243...27,194,018
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 decreases expression
multiple interactions
ISO
EXP
lead nitrate results in decreased expression of CYP7A1 mRNA
[IL1A gene mutant form co-treated with IL1B gene mutant form] inhibits the reaction [lead nitrate results in decreased expression of CYP7A1 mRNA]
CTD PMID:15475176, PMID:16049268, PMID:22293356 NCBI chr 5:19,358,734...19,368,431
Ensembl chr 5:19,358,734...19,368,431
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO lead nitrate results in increased expression of DDIT3 mRNA CTD PMID:14971657 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 multiple interactions ISO [lead nitrate results in increased abundance of Lead] which results in increased expression of DKK1 mRNA; [lead nitrate results in increased abundance of Lead] which results in increased expression of DKK1 protein; icaritin inhibits the reaction [[lead nitrate results in increased abundance of Lead] which results in increased expression of DKK1 mRNA]; icaritin inhibits the reaction [[lead nitrate results in increased abundance of Lead] which results in increased expression of DKK1 protein] CTD PMID:30731080 NCBI chr 1:248,952,896...248,956,579
Ensembl chr 1:248,895,738...248,898,607
JBrowse link
G Dnase1 deoxyribonuclease 1 multiple interactions ISO lead nitrate affects the reaction [DNASE1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [DNASE1 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr10:11,757,681...11,760,672
Ensembl chr10:11,757,682...11,760,620
JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha multiple interactions
decreases expression
ISO 4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline inhibits the reaction [lead nitrate results in decreased expression of DNMT3A mRNA]; E2F1 protein inhibits the reaction [lead nitrate results in decreased expression of DNMT3A mRNA]; RTKI cpd inhibits the reaction [lead nitrate results in decreased expression of DNMT3A mRNA]
lead nitrate results in decreased expression of DNMT3A mRNA; lead nitrate results in decreased expression of DNMT3A protein
CTD PMID:24639330 NCBI chr 6:28,205,375...28,346,052
Ensembl chr 6:28,235,695...28,340,577
JBrowse link
G E2f1 E2F transcription factor 1 multiple interactions ISO E2F1 protein inhibits the reaction [lead nitrate results in decreased expression of DNMT3A mRNA]; E2F1 protein inhibits the reaction [lead nitrate results in increased expression of PTGS2 mRNA]; lead nitrate inhibits the reaction [E2F1 protein results in decreased expression of PTGS2 mRNA] CTD PMID:24639330 NCBI chr 3:150,062,895...150,073,721
Ensembl chr 3:150,047,826...150,073,721
JBrowse link
G Egfl8 EGF-like-domain, multiple 8 increases expression EXP lead nitrate results in increased expression of EGFL8 protein CTD PMID:19332663 NCBI chr20:4,378,205...4,380,959
Ensembl chr20:4,378,206...4,380,600
JBrowse link
G Egfr epidermal growth factor receptor multiple interactions
increases phosphorylation
ISO EGFR mutant form affects the reaction [[lead nitrate results in increased expression of PLA2G4A mRNA] which results in increased secretion of Dinoprostone]; EGFR mutant form affects the reaction [lead nitrate results in increased expression of PLA2G4A mRNA]; EGFR mutant form affects the reaction [lead nitrate results in increased secretion of Dinoprostone]; EGFR promotes the reaction [lead nitrate results in increased expression of PLA2G4A mRNA]; RTKI cpd inhibits the reaction [lead nitrate results in increased phosphorylation of EGFR protein] CTD PMID:20850495 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
JBrowse link
G Eif2ak1 eukaryotic translation initiation factor 2 alpha kinase 1 increases response to substance
multiple interactions
ISO EIF2AK1 gene mutant form results in increased susceptibility to lead nitrate
[lead nitrate co-treated with EIF2AK1 gene mutant form] results in increased abundance of Bilirubin; [lead nitrate co-treated with EIF2AK1 gene mutant form] results in increased abundance of Malondialdehyde; [lead nitrate co-treated with EIF2AK1 gene mutant form] results in increased expression of HAMP mRNA
CTD PMID:25411909 NCBI chr12:12,749,026...12,782,078
Ensembl chr12:12,748,785...12,782,146
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 multiple interactions
increases phosphorylation
EXP puerarin inhibits the reaction [lead nitrate results in increased phosphorylation of EIF4EBP1 protein] CTD PMID:27762461 NCBI chr16:68,954,860...68,968,248
Ensembl chr16:68,954,875...68,968,248
JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit multiple interactions ISO lead nitrate affects the reaction [ERCC1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [ERCC1 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr 1:80,256,973...80,268,198
Ensembl chr 1:80,256,973...80,268,198
JBrowse link
G Ercc3 ERCC excision repair 3, TFIIH core complex helicase subunit multiple interactions ISO lead nitrate affects the reaction [ERCC3 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [ERCC3 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr18:25,037,668...25,068,380
Ensembl chr18:25,037,625...25,068,389
JBrowse link
G Ezr ezrin multiple interactions ISO lead nitrate affects the reaction [EZR affects the expression of MT1 mRNA]; lead nitrate affects the reaction [EZR affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr 1:47,287,872...47,331,412
Ensembl chr 1:47,287,874...47,331,412
JBrowse link
G Fabp9 fatty acid binding protein 9 decreases expression EXP lead nitrate results in decreased expression of FABP9 mRNA CTD PMID:21628963 NCBI chr 2:93,803,503...93,807,069
Ensembl chr 2:93,803,449...93,807,069
JBrowse link
G Fam71f1 family with sequence similarity 71, member F1 decreases expression EXP lead nitrate results in decreased expression of FAM71F1 mRNA CTD PMID:21628963 NCBI chr 4:56,591,719...56,615,157
Ensembl chr 4:56,591,715...56,615,158
JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 increases expression EXP lead nitrate results in increased expression of FDFT1 mRNA CTD PMID:15475176 NCBI chr15:46,339,248...46,367,302
Ensembl chr15:46,339,249...46,367,302
JBrowse link
G Fdps farnesyl diphosphate synthase increases expression EXP lead nitrate results in increased expression of FDPS mRNA CTD PMID:15475176 NCBI chr 2:188,403,595...188,413,219
Ensembl chr 2:188,392,858...188,413,219
JBrowse link
G Fhl1 four and a half LIM domains 1 decreases expression EXP lead nitrate results in decreased expression of FHL1 mRNA CTD PMID:21628963 NCBI chr  X:159,112,516...159,172,528
Ensembl chr  X:159,112,880...159,172,524
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression ISO lead nitrate results in increased expression of FOS mRNA CTD PMID:14971657 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Foxa2 forkhead box A2 multiple interactions ISO lead nitrate affects the reaction [FOXA2 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [FOXA2 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr 3:142,383,084...142,387,493
Ensembl chr 3:142,383,278...142,387,481
JBrowse link
G Ftl1 ferritin light chain 1 increases expression EXP lead nitrate results in increased expression of FTL protein CTD PMID:19332663 NCBI chr 1:101,448,190...101,450,034
Ensembl chr 1:101,448,346...101,449,829
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase decreases activity EXP lead nitrate results in decreased activity of G6PD protein CTD PMID:28557068 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression ISO lead nitrate results in increased expression of GADD45A mRNA CTD PMID:14971657 NCBI chr 4:97,782,512...97,784,814
Ensembl chr 4:97,782,512...97,784,842
JBrowse link
G Gfap glial fibrillary acidic protein multiple interactions
increases expression
EXP Ashwagandha inhibits the reaction [lead nitrate results in increased expression of GFAP mRNA]; Ashwagandha inhibits the reaction [lead nitrate results in increased expression of GFAP protein]
lead nitrate results in increased expression of GFAP mRNA; lead nitrate results in increased expression of GFAP protein
CTD PMID:24987671 NCBI chr10:90,990,762...90,999,435
Ensembl chr10:90,990,762...90,999,506
JBrowse link
G Ggnbp1 gametogenetin binding protein 1 decreases expression EXP lead nitrate results in decreased expression of GGNBP1 mRNA CTD PMID:21628963 NCBI chr20:5,618,973...5,625,320
Ensembl chr20:5,619,012...5,625,320
JBrowse link
G Gh1 growth hormone 1 multiple interactions
decreases secretion
EXP lead nitrate inhibits the reaction [GHRH protein results in increased expression of GH1 protein]
lead nitrate results in decreased secretion of GH1 protein
CTD PMID:12022635 NCBI chr10:94,486,204...94,488,181
Ensembl chr10:94,486,205...94,488,180
JBrowse link
G Ghrh growth hormone releasing hormone multiple interactions EXP lead nitrate inhibits the reaction [GHRH protein results in increased expression of GH1 protein] CTD PMID:12022635 NCBI chr 3:153,449,124...153,468,794
Ensembl chr 3:153,449,125...153,468,794
JBrowse link
G Gja5 gap junction protein, alpha 5 multiple interactions
increases expression
ISO lead nitrate affects the reaction [GJA5 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [GJA5 affects the expression of MT2 mRNA]
lead nitrate results in increased expression of GJA5 mRNA
CTD PMID:11891201 NCBI chr 2:199,162,745...199,184,942
Ensembl chr 2:199,162,745...199,184,939
JBrowse link
G Gjb2 gap junction protein, beta 2 multiple interactions ISO lead nitrate affects the reaction [GJB2 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [GJB2 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr15:37,377,313...37,394,494
Ensembl chr15:37,377,316...37,383,277
JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A multiple interactions ISO lead nitrate affects the reaction [GRIN2A affects the expression of MT1 mRNA]; lead nitrate affects the reaction [GRIN2A affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr10:5,707,806...6,123,568
Ensembl chr10:5,930,298...6,119,990
JBrowse link
G Grin2c glutamate ionotropic receptor NMDA type subunit 2C increases expression EXP lead nitrate results in increased expression of GRIN2C mRNA CTD PMID:23358146 NCBI chr10:103,798,290...103,816,923
Ensembl chr10:103,798,291...103,816,287
JBrowse link
G Gsg1 germ cell associated 1 decreases expression EXP lead nitrate results in decreased expression of GSG1 mRNA CTD PMID:21628963 NCBI chr 4:169,020,680...169,037,021
Ensembl chr 4:169,020,683...169,036,950
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions ISO [lead nitrate results in increased abundance of Lead] which results in decreased phosphorylation of GSK3B protein; icaritin inhibits the reaction [[lead nitrate results in increased abundance of Lead] which results in decreased phosphorylation of GSK3B protein] CTD PMID:30731080 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions
decreases activity
ISO mangiferin inhibits the reaction [lead nitrate results in decreased activity of GSR protein] CTD PMID:23451106 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Gstt1 glutathione S-transferase theta 1 multiple interactions ISO lead nitrate affects the reaction [GSTT1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [GSTT1 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr20:13,799,102...13,816,527
Ensembl chr20:13,799,102...13,816,526
JBrowse link
G Hamp hepcidin antimicrobial peptide multiple interactions ISO [lead nitrate co-treated with EIF2AK1 gene mutant form] results in increased expression of HAMP mRNA CTD PMID:25411909 NCBI chr 1:89,368,021...89,369,960
Ensembl chr 1:89,368,021...89,369,960
JBrowse link
G Hmgb4 high-mobility group box 4 decreases expression EXP lead nitrate results in decreased expression of HMGB4 mRNA CTD PMID:21628963 NCBI chr 5:146,445,545...146,446,227
Ensembl chr 5:146,445,545...146,446,227
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase increases expression
multiple interactions
ISO
EXP
lead nitrate results in increased expression of HMGCR mRNA
[IL1A gene mutant form co-treated with IL1B gene mutant form] inhibits the reaction [lead nitrate results in increased expression of HMGCR mRNA]
CTD PMID:15475176, PMID:16705668, PMID:22293356 NCBI chr 2:27,480,224...27,500,654
Ensembl chr 2:27,480,226...27,500,654
JBrowse link
G Hmox1 heme oxygenase 1 increases expression EXP lead nitrate results in increased expression of HMOX1 mRNA CTD PMID:23391631 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha decreases expression ISO lead nitrate results in decreased expression of HNF4A mRNA CTD PMID:16049268 NCBI chr 3:159,902,441...159,965,003
Ensembl chr 3:159,902,441...159,965,003
JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 multiple interactions ISO lead nitrate affects the reaction [HSP90AB1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [HSP90AB1 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr 9:17,817,791...17,823,163
Ensembl chr 9:17,817,721...17,823,243
JBrowse link
G Hspa2 heat shock protein family A (Hsp70) member 2 multiple interactions
decreases expression
increases expression
EXP Ashwagandha inhibits the reaction [lead nitrate results in increased expression of HSPA2 mRNA]
lead nitrate results in decreased expression of HSPA2 mRNA
CTD PMID:21628963, PMID:24987671 NCBI chr 6:99,433,575...99,436,288
Ensembl chr 6:99,433,550...99,436,289
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression ISO lead nitrate results in increased expression of HSPA5 protein
lead nitrate results in increased expression of HSPA5 mRNA
CTD PMID:14971657, PMID:20435106 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G Hspa9 heat shock protein family A (Hsp70) member 9 multiple interactions
increases expression
EXP Ashwagandha inhibits the reaction [lead nitrate results in increased expression of HSPA9 mRNA]; Ashwagandha inhibits the reaction [lead nitrate results in increased expression of HSPA9 protein]
lead nitrate results in increased expression of HSPA9 mRNA; lead nitrate results in increased expression of HSPA9 protein
CTD PMID:24987671 NCBI chr18:27,731,072...27,749,235
Ensembl chr18:27,731,072...27,749,235
JBrowse link
G Igf2 insulin-like growth factor 2 multiple interactions ISO lead nitrate affects the reaction [IGF2 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [IGF2 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr 1:215,828,102...215,839,081
Ensembl chr 1:215,828,102...215,846,911
JBrowse link
G Igfbp6 insulin-like growth factor binding protein 6 multiple interactions ISO lead nitrate affects the reaction [IGFBP6 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [IGFBP6 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr 7:143,749,385...143,754,018
Ensembl chr 7:143,749,221...143,754,054
JBrowse link
G Il1a interleukin 1 alpha multiple interactions
increases expression
ISO [IL1A gene mutant form co-treated with IL1B gene mutant form] inhibits the reaction [lead nitrate results in decreased expression of CYP7A1 mRNA]; [IL1A gene mutant form co-treated with IL1B gene mutant form] inhibits the reaction [lead nitrate results in increased expression of CYP51 mRNA]; [IL1A gene mutant form co-treated with IL1B gene mutant form] inhibits the reaction [lead nitrate results in increased expression of HMGCR mRNA]; [IL1A gene mutant form co-treated with IL1B gene mutant form] inhibits the reaction [lead nitrate results in increased expression of TNF mRNA]; [IL1A gene mutant form co-treated with IL1B gene mutant form] results in decreased susceptibility to lead nitrate
lead nitrate results in increased expression of IL1A mRNA
CTD PMID:22293356 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases expression
ISO
EXP
[IL1A gene mutant form co-treated with IL1B gene mutant form] inhibits the reaction [lead nitrate results in decreased expression of CYP7A1 mRNA]; [IL1A gene mutant form co-treated with IL1B gene mutant form] inhibits the reaction [lead nitrate results in increased expression of CYP51 mRNA]; [IL1A gene mutant form co-treated with IL1B gene mutant form] inhibits the reaction [lead nitrate results in increased expression of HMGCR mRNA]; [IL1A gene mutant form co-treated with IL1B gene mutant form] inhibits the reaction [lead nitrate results in increased expression of TNF mRNA]; [IL1A gene mutant form co-treated with IL1B gene mutant form] results in decreased susceptibility to lead nitrate
lead nitrate results in increased expression of IL1B mRNA
lead nitrate results in increased expression of IL1B mRNA; lead nitrate results in increased expression of IL1B protein
CTD PMID:15475176, PMID:16049268, PMID:22293356 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il2 interleukin 2 decreases secretion ISO lead nitrate results in decreased secretion of IL2 protein CTD PMID:27714827 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
JBrowse link
G Il6r interleukin 6 receptor multiple interactions ISO lead nitrate affects the reaction [IL6RA affects the expression of MT1 mRNA]; lead nitrate affects the reaction [IL6RA affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr 2:189,196,180...189,255,987
Ensembl chr 2:189,205,701...189,254,628
JBrowse link
G Iqcf1 IQ motif containing F1 decreases expression EXP lead nitrate results in decreased expression of IQCF1 mRNA CTD PMID:21628963 NCBI chr 8:115,191,919...115,195,599
Ensembl chr 8:115,193,146...115,195,668
JBrowse link
G Iqcf5 IQ motif containing F5 decreases expression EXP lead nitrate results in decreased expression of IQCF5 mRNA CTD PMID:21628963 NCBI chr 8:115,213,469...115,214,854
Ensembl chr 8:115,213,471...115,214,895
JBrowse link
G Itga6 integrin subunit alpha 6 multiple interactions ISO lead nitrate affects the reaction [ITGA6 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [ITGA6 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr 3:58,442,904...58,515,124
Ensembl chr 3:58,443,101...58,515,124
JBrowse link
G Itgam integrin subunit alpha M multiple interactions ISO lead nitrate affects the reaction [ITGAM affects the expression of MT1 mRNA]; lead nitrate affects the reaction [ITGAM affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr 1:199,495,312...199,545,738
Ensembl chr 1:199,495,298...199,623,960
JBrowse link
G Krt14 keratin 14 increases expression ISO lead nitrate results in increased expression of KRT14 protein CTD PMID:20435106 NCBI chr10:88,118,029...88,122,233
Ensembl chr10:88,055,823...88,122,233
JBrowse link
G Lamp1 lysosomal-associated membrane protein 1 increases expression ISO lead nitrate results in increased expression of LAMP1 protein CTD PMID:23376802 NCBI chr16:81,689,576...81,714,341
Ensembl chr16:81,689,335...81,714,419
JBrowse link
G Lamp2 lysosomal-associated membrane protein 2 increases expression ISO lead nitrate results in increased expression of LAMP2 protein CTD PMID:23376802 NCBI chr  X:124,722,628...124,766,079
Ensembl chr  X:124,722,628...124,766,044
JBrowse link
G Ldhc lactate dehydrogenase C decreases expression EXP lead nitrate results in decreased expression of LDHC mRNA CTD PMID:21628963 NCBI chr 1:102,914,875...102,931,843
Ensembl chr 1:102,915,191...102,931,839
JBrowse link
G Lrrc46 leucine rich repeat containing 46 decreases expression EXP lead nitrate results in decreased expression of LRRC46 mRNA CTD PMID:21628963 NCBI chr10:84,971,674...84,983,867
Ensembl chr10:84,971,676...84,976,170
JBrowse link
G Lta lymphotoxin alpha multiple interactions ISO lead nitrate affects the reaction [LTA affects the expression of MT1 mRNA]; lead nitrate affects the reaction [LTA affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr20:4,851,889...4,854,677
Ensembl chr20:4,852,496...4,854,677
JBrowse link
G Lypd4 Ly6/Plaur domain containing 4 decreases expression EXP lead nitrate results in decreased expression of LYPD4 mRNA CTD PMID:21628963 NCBI chr 1:81,728,552...81,734,286
Ensembl chr 1:81,728,552...81,733,957
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation
ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [lead nitrate results in increased phosphorylation of MAPK1 protein]; 4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline inhibits the reaction [lead nitrate results in increased phosphorylation of MAPK1 protein]; RTKI cpd inhibits the reaction [lead nitrate results in increased phosphorylation of MAPK1 protein]
mangiferin inhibits the reaction [lead nitrate results in increased phosphorylation of MAPK1 protein]
CTD PMID:20850495, PMID:22502979, PMID:23451106 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation
ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [lead nitrate results in increased phosphorylation of MAPK3 protein]; 4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline inhibits the reaction [lead nitrate results in increased phosphorylation of MAPK3 protein]; RTKI cpd inhibits the reaction [lead nitrate results in increased phosphorylation of MAPK3 protein]
mangiferin inhibits the reaction [lead nitrate results in increased phosphorylation of MAPK3 protein]
CTD PMID:20850495, PMID:22502979, PMID:23451106 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Marchf11 membrane associated ring-CH-type finger 11 decreases expression EXP lead nitrate results in decreased expression of MARCHF11 mRNA CTD PMID:21628963 NCBI chr 2:78,825,053...78,926,402
Ensembl chr 2:78,825,074...78,926,395
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member multiple interactions ISO lead nitrate affects the reaction [MCL1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [MCL1 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr 2:197,786,212...197,788,992 JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase multiple interactions ISO lead nitrate affects the reaction [MET affects the expression of MT1 mRNA]; lead nitrate affects the reaction [MET affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr 4:44,747,467...44,854,628
Ensembl chr 4:44,774,741...44,852,665
JBrowse link
G Mgst1 microsomal glutathione S-transferase 1 multiple interactions ISO lead nitrate affects the reaction [MGST1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [MGST1 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr 4:172,119,382...172,134,609
Ensembl chr 4:172,119,331...172,134,607
JBrowse link
G Mroh2b maestro heat-like repeat family member 2B decreases expression EXP lead nitrate results in decreased expression of MROH2B mRNA CTD PMID:21628963 NCBI chr 2:54,621,140...54,675,142 JBrowse link
G Mt-co1 mitochondrially encoded cytochrome c oxidase I multiple interactions
decreases expression
EXP puerarin inhibits the reaction [lead nitrate results in decreased expression of COX1 mRNA] CTD PMID:23315276 NCBI chr MT:5,323...6,867
Ensembl chr MT:5,323...6,867
JBrowse link
G Mt-co2 mitochondrially encoded cytochrome c oxidase II multiple interactions
decreases expression
EXP puerarin inhibits the reaction [lead nitrate results in decreased expression of COX2 mRNA] CTD PMID:23315276 NCBI chr MT:7,006...7,689
Ensembl chr MT:7,006...7,689
JBrowse link
G Mt-co3 mitochondrially encoded cytochrome c oxidase III multiple interactions
decreases expression
EXP puerarin inhibits the reaction [lead nitrate results in decreased expression of COX3 mRNA] CTD PMID:23315276 NCBI chr MT:8,599...9,382
Ensembl chr MT:8,599...9,382
JBrowse link
G Mt1 metallothionein 1 affects localization
decreases response to substance
increases expression
multiple interactions
ISO lead nitrate affects the localization of MT1 protein
MT1 results in decreased susceptibility to lead nitrate
lead nitrate results in increased expression of MT1 mRNA
lead nitrate affects the reaction [CASP7 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [CCNG1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [CTNNA1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [CUX2 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [DNASE1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [ERCC1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [ERCC3 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [EZR affects the expression of MT1 mRNA]; lead nitrate affects the reaction [FOXA2 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [GJA5 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [GJB2 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [GRIN2A affects the expression of MT1 mRNA]; lead nitrate affects the reaction [GSTT1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [HSP90AB1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [IGF2 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [IGFBP6 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [IL6RA affects the expression of MT1 mRNA]; lead nitrate affects the reaction [ITGA6 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [ITGAM affects the expression of MT1 mRNA]; lead nitrate affects the reaction [LTA affects the expression of MT1 mRNA]; lead nitrate affects the reaction [MCL1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [MET affects the expression of MT1 mRNA]; lead nitrate affects the reaction [MGST1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [MYC affects the expression of MT1 mRNA]; lead nitrate affects the reaction [NFKBIB affects the expression of MT1 mRNA]; lead nitrate affects the reaction [NUMB affects the expression of MT1 mRNA]; lead nitrate affects the reaction [PIAS2 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [POLD1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [POU3F3 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [RAD23 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [RBL2 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [RUNX1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [SERPINA1B affects the expression of MT1 mRNA]; lead nitrate affects the reaction [SOCS1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [SP3 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [SQSTM1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [SUMO1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [TBX2 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [TNFRSF1A affects the expression of MT1 mRNA]; lead nitrate affects the reaction [TNFRSF1B affects the expression of MT1 mRNA]; lead nitrate affects the reaction [TRIM27 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [TSG101 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [TTF1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [WNT4 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [ZFHX3 affects the expression of MT1 mRNA]; MT1 protein promotes the reaction [lead nitrate results in increased expression of SNCA mRNA]
CTD PMID:11891201, PMID:19542206 NCBI chr19:11,301,991...11,303,007
Ensembl chr17:78,793,336...78,793,724
JBrowse link
G Mt2A metallothionein 2A multiple interactions
decreases response to substance
ISO lead nitrate affects the reaction [CASP7 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [CCNG1 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [CTNNA1 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [CUX2 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [DNASE1 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [ERCC1 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [ERCC3 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [EZR affects the expression of MT2 mRNA]; lead nitrate affects the reaction [FOXA2 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [GJA5 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [GJB2 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [GRIN2A affects the expression of MT2 mRNA]; lead nitrate affects the reaction [GSTT1 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [HSP90AB1 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [IGF2 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [IGFBP6 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [IL6RA affects the expression of MT2 mRNA]; lead nitrate affects the reaction [ITGA6 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [ITGAM affects the expression of MT2 mRNA]; lead nitrate affects the reaction [LTA affects the expression of MT2 mRNA]; lead nitrate affects the reaction [MCL1 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [MET affects the expression of MT2 mRNA]; lead nitrate affects the reaction [MGST1 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [MYC affects the expression of MT2 mRNA]; lead nitrate affects the reaction [NFKBIB affects the expression of MT2 mRNA]; lead nitrate affects the reaction [NUMB affects the expression of MT2 mRNA]; lead nitrate affects the reaction [PIAS2 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [POLD1 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [POU3F3 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [RAD23 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [RBL2 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [RUNX1 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [SERPINA1B affects the expression of MT2 mRNA]; lead nitrate affects the reaction [SOCS1 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [SP3 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [SQSTM1 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [SUMO1 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [TBX2 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [TNFRSF1A affects the expression of MT2 mRNA]; lead nitrate affects the reaction [TNFRSF1B affects the expression of MT2 mRNA]; lead nitrate affects the reaction [TRIM27 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [TSG101 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [TTF1 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [WNT4 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [ZFHX3 affects the expression of MT2 mRNA]
MT2 results in decreased susceptibility to lead nitrate
CTD PMID:11891201 NCBI chr19:11,307,966...11,308,740
Ensembl chr19:11,307,967...11,308,740
JBrowse link
G Mtor mechanistic target of rapamycin kinase increases phosphorylation
multiple interactions
EXP lead nitrate results in increased phosphorylation of MTOR protein
puerarin inhibits the reaction [lead nitrate results in increased phosphorylation of MTOR protein]
CTD PMID:27762461 NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor multiple interactions ISO lead nitrate affects the reaction [MYC affects the expression of MT1 mRNA]; lead nitrate affects the reaction [MYC affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Myh6 myosin heavy chain 6 decreases expression EXP lead nitrate results in decreased expression of MYH6 protein CTD PMID:23391631 NCBI chr15:33,605,653...33,629,730
Ensembl chr15:33,605,654...33,629,699
JBrowse link
G Myh7 myosin heavy chain 7 increases expression
multiple interactions
EXP lead nitrate results in increased expression of MYH7 mRNA; lead nitrate results in increased expression of MYH7 protein
resveratrol inhibits the reaction [lead nitrate results in increased expression of MYH7 mRNA]
CTD PMID:23391631 NCBI chr15:33,605,769...33,657,761
Ensembl chr15:33,634,422...33,656,089
JBrowse link
G Ncam1 neural cell adhesion molecule 1 multiple interactions
decreases expression
EXP Ashwagandha inhibits the reaction [lead nitrate results in decreased expression of NCAM1 mRNA]; Ashwagandha inhibits the reaction [lead nitrate results in decreased expression of NCAM1 protein]
lead nitrate results in decreased expression of NCAM1 mRNA; lead nitrate results in decreased expression of NCAM1 protein
CTD PMID:24987671 NCBI chr 8:53,836,797...54,134,881
Ensembl chr 8:53,839,098...53,901,358
JBrowse link
G Nfkbia NFKB inhibitor alpha decreases expression
multiple interactions
ISO lead nitrate results in decreased expression of NFKBIA protein
mangiferin inhibits the reaction [lead nitrate results in decreased expression of NFKBIA protein]
CTD PMID:23451106 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Nfkbib NFKB inhibitor beta multiple interactions ISO lead nitrate affects the reaction [NFKBIB affects the expression of MT1 mRNA]; lead nitrate affects the reaction [NFKBIB affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr 1:86,941,073...86,948,845
Ensembl chr 1:86,941,074...86,948,845
JBrowse link
G Nppb natriuretic peptide B increases expression EXP lead nitrate results in increased expression of NPPB mRNA CTD PMID:23391631 NCBI chr 5:164,796,176...164,797,538
Ensembl chr 5:164,796,185...164,797,531
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression EXP lead nitrate results in increased expression of NQO1 mRNA CTD PMID:23391631 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 decreases expression ISO
EXP
lead nitrate results in decreased expression of NR0B2 mRNA CTD PMID:15475176, PMID:16049268 NCBI chr 5:151,776,004...151,779,319
Ensembl chr 5:151,776,004...151,779,319
JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 decreases expression EXP lead nitrate results in decreased expression of NR1H3 mRNA CTD PMID:15475176 NCBI chr 3:80,004,130...80,014,197
Ensembl chr 3:80,004,130...80,012,750
JBrowse link
G Nr5a2 nuclear receptor subfamily 5, group A, member 2 increases expression ISO lead nitrate results in increased expression of NR5A2 mRNA CTD PMID:16049268 NCBI chr13:53,750,470...53,870,288
Ensembl chr13:53,750,473...53,870,428
JBrowse link
G Numb NUMB, endocytic adaptor protein multiple interactions ISO lead nitrate affects the reaction [NUMB affects the expression of MT1 mRNA]; lead nitrate affects the reaction [NUMB affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr 6:107,279,917...107,325,345
Ensembl chr 6:107,279,920...107,325,345
JBrowse link
G Odf1 outer dense fiber of sperm tails 1 decreases expression EXP lead nitrate results in decreased expression of ODF1 mRNA CTD PMID:21628963 NCBI chr 7:77,066,580...77,074,712
Ensembl chr 7:77,066,955...77,074,711
JBrowse link
G Oxct2a 3-oxoacid CoA transferase 2A decreases expression EXP lead nitrate results in decreased expression of OXCT2A mRNA CTD PMID:21628963 NCBI chr 5:141,016,542...141,018,832 JBrowse link
G Paqr5 progestin and adipoQ receptor family member 5 decreases expression EXP lead nitrate results in decreased expression of PAQR5 mRNA CTD PMID:21628963 NCBI chr 8:66,899,990...66,976,010
Ensembl chr 8:66,899,990...66,975,932
JBrowse link
G Pias2 protein inhibitor of activated STAT, 2 multiple interactions ISO lead nitrate affects the reaction [PIAS2 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [PIAS2 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr18:73,479,863...73,524,956
Ensembl chr18:73,378,662...73,524,956
JBrowse link
G Pla2g4a phospholipase A2 group IVA multiple interactions
increases expression
ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[lead nitrate results in increased expression of PLA2G4A mRNA] which results in increased secretion of Dinoprostone]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [lead nitrate results in increased expression of PLA2G4A mRNA]; 2-aminoethoxydiphenyl borate inhibits the reaction [lead nitrate results in increased expression of PLA2G4A mRNA]; 4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline inhibits the reaction [[lead nitrate results in increased expression of PLA2G4A mRNA] which results in increased secretion of Dinoprostone]; 4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline inhibits the reaction [lead nitrate results in increased expression of PLA2G4A mRNA]; [lead nitrate results in increased expression of PLA2G4A mRNA] which results in increased secretion of Dinoprostone; EGFR mutant form affects the reaction [[lead nitrate results in increased expression of PLA2G4A mRNA] which results in increased secretion of Dinoprostone]; EGFR mutant form affects the reaction [lead nitrate results in increased expression of PLA2G4A mRNA]; EGFR promotes the reaction [lead nitrate results in increased expression of PLA2G4A mRNA]; RTKI cpd inhibits the reaction [[lead nitrate results in increased expression of PLA2G4A mRNA] which results in increased secretion of Dinoprostone]; RTKI cpd inhibits the reaction [lead nitrate results in increased expression of PLA2G4A mRNA] CTD PMID:20850495 NCBI chr13:67,062,252...67,206,688
Ensembl chr13:66,988,937...67,206,693
JBrowse link
G Pold1 DNA polymerase delta 1, catalytic subunit multiple interactions ISO lead nitrate affects the reaction [POLD1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [POLD1 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr 1:100,538,066...100,554,105
Ensembl chr 1:100,537,900...100,554,488
JBrowse link
G Pou3f3 POU class 3 homeobox 3 multiple interactions ISO lead nitrate affects the reaction [POU3F3 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [POU3F3 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr 9:49,479,148...49,482,246
Ensembl chr 9:49,479,023...49,482,252
JBrowse link
G Prm1 protamine 1 decreases expression EXP lead nitrate results in decreased expression of PRM1 mRNA CTD PMID:21628963 NCBI chr10:4,945,995...4,946,241
Ensembl chr10:4,945,911...4,946,397
JBrowse link
G Prm3 protamine 3 decreases expression EXP lead nitrate results in decreased expression of PRM3 mRNA CTD PMID:21628963 NCBI chr10:4,951,557...4,952,071
Ensembl chr10:4,951,557...4,952,071
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases expression
ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[lead nitrate results in increased expression of PTGS2 mRNA] which results in increased secretion of Dinoprostone]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [lead nitrate results in increased expression of PTGS2 mRNA]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [lead nitrate results in increased expression of PTGS2 mRNA]; 4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline inhibits the reaction [[lead nitrate results in increased expression of PTGS2 mRNA] which results in increased secretion of Dinoprostone]; 4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline inhibits the reaction [lead nitrate results in increased expression of PTGS2 mRNA]; 4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline inhibits the reaction [lead nitrate results in increased expression of PTGS2 protein]; [lead nitrate results in increased expression of PTGS2 mRNA] which results in increased secretion of Dinoprostone; Decitabine promotes the reaction [lead nitrate results in increased expression of PTGS2 mRNA]; E2F1 protein inhibits the reaction [lead nitrate results in increased expression of PTGS2 mRNA]; lead nitrate inhibits the reaction [E2F1 protein results in decreased expression of PTGS2 mRNA]; lead nitrate promotes the reaction [RB1 protein results in increased expression of PTGS2 mRNA]; RB1 protein promotes the reaction [lead nitrate results in increased expression of PTGS2 mRNA]; RTKI cpd inhibits the reaction [[lead nitrate results in increased expression of PTGS2 mRNA] which results in increased secretion of Dinoprostone]; RTKI cpd inhibits the reaction [lead nitrate results in increased expression of PTGS2 mRNA]; RTKI cpd inhibits the reaction [lead nitrate results in increased expression of PTGS2 protein]
lead nitrate results in increased expression of PTGS2 mRNA; lead nitrate results in increased expression of PTGS2 protein
CTD PMID:20850495, PMID:21435385, PMID:24639330 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Rb1 RB transcriptional corepressor 1 multiple interactions
increases expression
ISO 4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline inhibits the reaction [lead nitrate results in increased expression of RB1 mRNA]; 4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline inhibits the reaction [lead nitrate results in increased expression of RB1 protein]; lead nitrate promotes the reaction [RB1 protein results in increased expression of PTGS2 mRNA]; RB1 protein promotes the reaction [lead nitrate results in increased expression of PTGS2 mRNA]; RTKI cpd inhibits the reaction [lead nitrate results in increased expression of RB1 mRNA]; RTKI cpd inhibits the reaction [lead nitrate results in increased expression of RB1 protein] CTD PMID:24639330 NCBI chr15:55,081,582...55,209,060
Ensembl chr15:55,083,140...55,209,342
JBrowse link
G Rbl2 RB transcriptional corepressor like 2 multiple interactions ISO lead nitrate affects the reaction [RBL2 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [RBL2 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr19:17,300,088...17,346,865
Ensembl chr19:17,300,089...17,346,808
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
increases expression
ISO mangiferin inhibits the reaction [lead nitrate results in increased expression of RELA protein] CTD PMID:23451106 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G RGD1359334 similar to hypothetical protein FLJ20519 decreases expression EXP lead nitrate results in decreased expression of RGD1359334 mRNA CTD PMID:21628963 NCBI chr 2:196,411,937...196,415,530
Ensembl chr 2:196,411,964...196,415,530
JBrowse link
G Ribc2 RIB43A domain with coiled-coils 2 decreases expression EXP lead nitrate results in decreased expression of RIBC2 mRNA CTD PMID:21628963 NCBI chr 7:126,028,371...126,043,371
Ensembl chr 7:126,028,350...126,043,847
JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 multiple interactions
increases phosphorylation
EXP puerarin inhibits the reaction [lead nitrate results in increased phosphorylation of RPS6KB1 protein] CTD PMID:27762461 NCBI chr10:73,824,200...73,865,503
Ensembl chr10:73,824,202...73,865,364
JBrowse link
G Runx1 RUNX family transcription factor 1 multiple interactions ISO lead nitrate affects the reaction [RUNX1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [RUNX1 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr11:32,765,147...33,003,061
Ensembl chr11:32,769,165...33,003,021
JBrowse link
G Runx2 RUNX family transcription factor 2 multiple interactions ISO [lead nitrate results in increased abundance of Lead] which results in decreased expression of RUNX2 mRNA; [lead nitrate results in increased abundance of Lead] which results in decreased expression of RUNX2 protein; icaritin inhibits the reaction [[lead nitrate results in increased abundance of Lead] which results in decreased expression of RUNX2 mRNA]; icaritin inhibits the reaction [[lead nitrate results in increased abundance of Lead] which results in decreased expression of RUNX2 protein] CTD PMID:30731080 NCBI chr 9:18,564,743...18,773,092
Ensembl chr 9:18,564,927...18,773,092
JBrowse link
G Smcp sperm mitochondria-associated cysteine-rich protein decreases expression EXP lead nitrate results in decreased expression of SMCP mRNA CTD PMID:21628963 NCBI chr 2:192,775,425...192,780,631
Ensembl chr 2:192,775,437...192,780,631
JBrowse link
G Snca synuclein alpha affects localization
multiple interactions
increases expression
ISO lead nitrate affects the localization of SNCA protein
MT1 protein promotes the reaction [lead nitrate results in increased expression of SNCA mRNA]
CTD PMID:19542206 NCBI chr 4:90,782,412...90,883,236
Ensembl chr 4:90,782,374...90,882,285
JBrowse link
G Socs1 suppressor of cytokine signaling 1 multiple interactions ISO lead nitrate affects the reaction [SOCS1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [SOCS1 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr10:4,956,795...4,958,472
Ensembl chr10:4,957,326...4,958,461
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions
decreases activity
EXP Ashwagandha inhibits the reaction [lead nitrate results in decreased activity of SOD1 protein] CTD PMID:24987671 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Sp3 Sp3 transcription factor multiple interactions
decreases expression
ISO lead nitrate affects the reaction [SP3 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [SP3 affects the expression of MT2 mRNA]
lead nitrate results in decreased expression of SP3 mRNA
CTD PMID:11891201 NCBI chr 3:59,644,579...59,689,011
Ensembl chr 3:59,646,015...59,688,692
JBrowse link
G Spata18 spermatogenesis associated 18 decreases expression EXP lead nitrate results in decreased expression of SPATA18 mRNA CTD PMID:21628963 NCBI chr14:37,081,529...37,108,245
Ensembl chr14:37,081,427...37,108,341
JBrowse link
G Spata20 spermatogenesis associated 20 decreases expression EXP lead nitrate results in decreased expression of SPATA20 mRNA CTD PMID:21628963 NCBI chr10:82,202,619...82,217,260
Ensembl chr10:82,202,605...82,209,459
JBrowse link
G Spata21 spermatogenesis associated 21 decreases expression EXP lead nitrate results in decreased expression of SPATA21 mRNA CTD PMID:21628963 NCBI chr 5:159,612,541...159,638,073
Ensembl chr 5:159,612,762...159,638,076
JBrowse link
G Spata6 spermatogenesis associated 6 decreases expression EXP lead nitrate results in decreased expression of SPATA6 mRNA CTD PMID:21628963 NCBI chr 5:131,719,922...131,803,853
Ensembl chr 5:131,719,922...131,803,853
JBrowse link
G Spetex-2B Spetex-2B protein decreases expression EXP lead nitrate results in decreased expression of SPETEX-2B mRNA CTD PMID:21628963 NCBI chr 8:1,932,820...1,933,017 JBrowse link
G Spetex-2D Spetex-2D protein decreases expression EXP lead nitrate results in decreased expression of SPETEX-2D mRNA CTD PMID:21628963
G Spetex-2F Spetex-2F protein decreases expression EXP lead nitrate results in decreased expression of SPETEX-2F mRNA CTD PMID:21628963 NCBI chr15:5,463,852...5,509,839
Ensembl chr15:5,414,416...5,510,289
JBrowse link
G Sqstm1 sequestosome 1 multiple interactions
increases expression
ISO
EXP
lead nitrate affects the reaction [SQSTM1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [SQSTM1 affects the expression of MT2 mRNA]
puerarin inhibits the reaction [lead nitrate results in increased expression of SQSTM1 protein]
CTD PMID:11891201, PMID:27762461 NCBI chr10:35,704,728...35,716,316
Ensembl chr10:35,704,730...35,716,294
JBrowse link
G Srebf2 sterol regulatory element binding transcription factor 2 increases expression EXP lead nitrate results in increased expression of SREBF2 mRNA CTD PMID:15475176, PMID:16705668 NCBI chr 7:123,381,082...123,438,605
Ensembl chr 7:123,381,077...123,438,603
JBrowse link
G Sumo1 small ubiquitin-like modifier 1 multiple interactions ISO lead nitrate affects the reaction [SUMO1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [SUMO1 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr 9:66,453,428...66,483,614
Ensembl chr 9:66,453,438...66,483,614
JBrowse link
G Tbx2 T-box transcription factor 2 multiple interactions ISO lead nitrate affects the reaction [TBX2 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [TBX2 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr10:73,278,932...73,290,764
Ensembl chr10:73,279,119...73,289,921
JBrowse link
G Tekt2 tektin 2 decreases expression EXP lead nitrate results in decreased expression of TEKT2 mRNA CTD PMID:21628963 NCBI chr 5:144,341,955...144,345,500
Ensembl chr 5:144,341,946...144,345,531
JBrowse link
G Tekt4 tektin 4 decreases expression EXP lead nitrate results in decreased expression of TEKT4 mRNA CTD PMID:21628963 NCBI chr10:14,828,642...14,833,818
Ensembl chr10:14,828,597...14,833,827
JBrowse link
G Tmod1 tropomodulin 1 decreases expression EXP lead nitrate results in decreased expression of TMOD1 mRNA CTD PMID:21628963 NCBI chr 5:61,635,244...61,712,052
Ensembl chr 5:61,657,507...61,712,051
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
ISO
EXP
[IL1A gene mutant form co-treated with IL1B gene mutant form] inhibits the reaction [lead nitrate results in increased expression of TNF mRNA]
Lead nitrate increases expression of Tnf mRNA in liver
CTD PMID:15475176, PMID:16049268, PMID:22293356, PMID:9049203, PMID:7943184 RGD:14995487, RGD:14995476 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A multiple interactions ISO lead nitrate affects the reaction [TNFRSF1A affects the expression of MT1 mRNA]; lead nitrate affects the reaction [TNFRSF1A affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr 4:157,864,905...157,877,634
Ensembl chr 4:157,864,969...157,877,633
JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B multiple interactions ISO lead nitrate affects the reaction [TNFRSF1B affects the expression of MT1 mRNA]; lead nitrate affects the reaction [TNFRSF1B affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr 5:163,136,390...163,167,299
Ensembl chr 5:163,136,390...163,167,299
JBrowse link
G Tnp1 transition protein 1 decreases expression EXP lead nitrate results in decreased expression of TNP1 mRNA CTD PMID:21628963 NCBI chr 9:80,294,837...80,295,446
Ensembl chr 9:80,294,840...80,295,446
JBrowse link
G Tnp2 transition protein 2 decreases expression EXP lead nitrate results in decreased expression of TNP2 mRNA CTD PMID:21628963 NCBI chr10:4,953,898...4,954,626
Ensembl chr10:4,953,879...4,954,624
JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO [lead nitrate results in increased abundance of Lead] which results in increased expression of TP53 mRNA; titanium dioxide inhibits the reaction [[lead nitrate results in increased abundance of Lead] which results in increased expression of TP53 mRNA] CTD PMID:30738203 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Tppp2 tubulin polymerization-promoting protein family member 2 decreases expression EXP lead nitrate results in decreased expression of TPPP2 mRNA CTD PMID:21628963 NCBI chr15:28,319,175...28,321,469
Ensembl chr15:28,319,136...28,321,476
JBrowse link
G Trim27 tripartite motif-containing 27 multiple interactions ISO lead nitrate affects the reaction [TRIM27 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [TRIM27 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr17:45,613,863...45,626,212
Ensembl chr17:45,613,864...45,626,212
JBrowse link
G Trpm2 transient receptor potential cation channel, subfamily M, member 2 multiple interactions ISO lead nitrate inhibits the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein] CTD PMID:22750002 NCBI chr20:11,434,062...11,482,880
Ensembl chr20:11,436,267...11,482,051
JBrowse link
G Tsc22d3 TSC22 domain family, member 3 multiple interactions ISO [lead nitrate results in increased abundance of Lead] inhibits the reaction [Hydrocortisone results in increased expression of TSC22D3 mRNA] CTD PMID:29957541 NCBI chr  X:111,884,285...111,944,693
Ensembl chr  X:111,884,295...111,887,906
JBrowse link
G Tsg101 tumor susceptibility 101 multiple interactions ISO lead nitrate affects the reaction [TSG101 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [TSG101 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr 1:102,941,151...102,971,017
Ensembl chr 1:102,941,231...102,970,950
JBrowse link
G Tssk2 testis-specific serine kinase 2 decreases expression EXP lead nitrate results in decreased expression of TSSK2 mRNA CTD PMID:21628963 NCBI chr11:87,235,058...87,236,413
Ensembl chr11:87,221,613...87,236,445
JBrowse link
G Tssk3 testis-specific serine kinase 3 decreases expression EXP lead nitrate results in decreased expression of TSSK3 mRNA CTD PMID:21628963 NCBI chr 5:147,689,490...147,691,930
Ensembl chr 5:147,690,239...147,691,997
JBrowse link
G Ttf1 transcription termination factor 1 multiple interactions ISO lead nitrate affects the reaction [TTF1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [TTF1 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr 3:7,635,630...7,660,153
Ensembl chr 3:7,635,933...7,660,673
JBrowse link
G Tuba8 tubulin, alpha 8 decreases expression EXP lead nitrate results in decreased expression of TUBA8 mRNA CTD PMID:21628963 NCBI chr 4:153,774,511...153,791,223
Ensembl chr 4:153,774,486...153,791,328
JBrowse link
G Tulp2 TUB like protein 2 decreases expression EXP lead nitrate results in decreased expression of TULP2 mRNA CTD PMID:21628963 NCBI chr 1:101,474,334...101,511,621
Ensembl chr 1:101,474,334...101,511,412
JBrowse link
G Wnt3a Wnt family member 3A multiple interactions ISO [lead nitrate results in increased abundance of Lead] which results in decreased expression of WNT3A mRNA; [lead nitrate results in increased abundance of Lead] which results in decreased expression of WNT3A protein; icaritin inhibits the reaction [[lead nitrate results in increased abundance of Lead] which results in decreased expression of WNT3A mRNA]; icaritin inhibits the reaction [[lead nitrate results in increased abundance of Lead] which results in decreased expression of WNT3A protein] CTD PMID:30731080 NCBI chr10:45,598,898...45,643,151
Ensembl chr10:45,598,912...45,638,035
JBrowse link
G Wnt4 Wnt family member 4 multiple interactions ISO lead nitrate affects the reaction [WNT4 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [WNT4 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr 5:155,649,238...155,668,065
Ensembl chr 5:155,649,217...155,672,579
JBrowse link
G Zfhx3 zinc finger homeobox 3 multiple interactions ISO lead nitrate affects the reaction [ZFHX3 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [ZFHX3 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr19:42,753,983...42,925,794
Ensembl chr19:42,758,127...42,920,344
JBrowse link
G Znrf4 zinc and ring finger 4 decreases expression EXP lead nitrate results in decreased expression of ZNRF4 mRNA CTD PMID:21628963 NCBI chr 9:10,535,340...10,536,528
Ensembl chr 9:10,535,340...10,536,528
JBrowse link
potassium nitrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccdc120 coiled-coil domain containing 120 decreases expression ISO potassium nitrate results in decreased expression of CCDC120 mRNA CTD PMID:15878651 NCBI chr  X:15,610,230...15,616,727
Ensembl chr  X:15,598,652...15,617,665
JBrowse link
G Clk1 CDC-like kinase 1 decreases expression ISO potassium nitrate results in decreased expression of CLK1 mRNA CTD PMID:15878651 NCBI chr 9:65,296,777...65,308,017
Ensembl chr 9:65,296,778...65,307,995
JBrowse link
G Dclre1c DNA cross-link repair 1C increases expression ISO potassium nitrate results in increased expression of DCLRE1C mRNA CTD PMID:15878651 NCBI chr17:78,782,512...78,812,140
Ensembl chr17:78,783,437...78,812,111
JBrowse link
G Fth1 ferritin heavy chain 1 increases expression ISO potassium nitrate results in increased expression of FTH1 mRNA CTD PMID:15878651 NCBI chr 1:226,030,940...226,033,228
Ensembl chr 1:226,030,938...226,033,228
JBrowse link
G Ftl1 ferritin light chain 1 increases expression ISO potassium nitrate results in increased expression of FTL mRNA CTD PMID:15878651 NCBI chr 1:101,448,190...101,450,034
Ensembl chr 1:101,448,346...101,449,829
JBrowse link
G Hmgb1 high mobility group box 1 increases expression ISO potassium nitrate results in increased expression of HMGB1 mRNA CTD PMID:15878651 NCBI chr12:7,082,529...7,090,246
Ensembl chr16:37,500,017...37,502,237
JBrowse link
G Hmgb2 high mobility group box 2 increases expression ISO potassium nitrate results in increased expression of HMGB2 mRNA CTD PMID:15878651 NCBI chr16:36,077,615...36,080,191
Ensembl chr16:36,077,617...36,080,191
Ensembl chr11:36,077,617...36,080,191
JBrowse link
G Pcna proliferating cell nuclear antigen increases expression ISO potassium nitrate results in increased expression of PCNA mRNA CTD PMID:15878651 NCBI chr 3:124,880,698...124,884,570
Ensembl chr 3:124,880,698...124,884,570
JBrowse link
G Septin7 septin 7 decreases expression ISO potassium nitrate results in decreased expression of SEPTIN7 mRNA CTD PMID:15878651 NCBI chr 8:26,412,910...26,476,615
Ensembl chr 8:26,413,233...26,476,611
JBrowse link
G Stmn1 stathmin 1 increases expression ISO potassium nitrate results in increased expression of STMN1 mRNA CTD PMID:15878651 NCBI chr 5:152,680,412...152,686,807
Ensembl chr 5:152,680,407...152,686,806
JBrowse link
G Vegfa vascular endothelial growth factor A decreases expression ISO potassium nitrate results in decreased expression of VEGFA mRNA CTD PMID:15878651 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
silver(1+) nitrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP binding cassette subfamily C member 1 multiple interactions
increases response to substance
ISO [ABCC1 protein results in increased susceptibility to Silver Nitrate] which results in decreased export of calcein AM CTD PMID:27376922 NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196
JBrowse link
G Atm ATM serine/threonine kinase increases expression ISO Silver Nitrate analog results in increased expression of ATM mRNA CTD PMID:22831968 NCBI chr 8:58,015,938...58,119,973
Ensembl chr 8:58,015,940...58,120,045
JBrowse link
G Atr ATR serine/threonine kinase increases expression ISO Silver Nitrate analog results in increased expression of ATR mRNA CTD PMID:22831968 NCBI chr 8:103,673,578...103,770,886
Ensembl chr 8:103,673,411...103,770,947
JBrowse link
G Aurka aurora kinase A increases expression
multiple interactions
ISO Silver Nitrate results in increased expression of AURKA protein modified form
CFL1 mRNA promotes the reaction [Silver Nitrate results in increased expression of AURKA protein modified form]
CTD PMID:28499611 NCBI chr 3:170,364,177...170,380,278
Ensembl chr 3:170,364,181...170,378,210
JBrowse link
G Aurkb aurora kinase B increases phosphorylation
multiple interactions
ISO Silver Nitrate results in increased phosphorylation of AURKB protein
CFL1 mRNA promotes the reaction [Silver Nitrate results in increased phosphorylation of AURKB protein]
CTD PMID:28499611 NCBI chr10:55,625,860...55,632,399
Ensembl chr10:55,626,741...55,634,991
JBrowse link
G Aurkc aurora kinase C increases expression
multiple interactions
ISO Silver Nitrate results in increased expression of AURKC protein modified form
CFL1 mRNA promotes the reaction [Silver Nitrate results in increased expression of AURKC protein modified form]
CTD PMID:28499611 NCBI chr 1:69,958,452...69,964,546
Ensembl chr 1:69,958,452...69,963,592
JBrowse link
G Bub1 BUB1 mitotic checkpoint serine/threonine kinase increases expression ISO Silver Nitrate analog results in increased expression of BUB1 mRNA; Silver Nitrate results in increased expression of BUB1 mRNA CTD PMID:22831968 NCBI chr 3:120,373,604...120,404,910
Ensembl chr 3:120,373,604...120,404,910
JBrowse link
G Bub1b BUB1 mitotic checkpoint serine/threonine kinase B increases expression ISO Silver Nitrate analog results in increased expression of BUB1B mRNA; Silver Nitrate results in increased expression of BUB1B mRNA CTD PMID:22831968 NCBI chr 3:110,367,949...110,420,471
Ensembl chr 3:110,367,939...110,420,458
JBrowse link
G Cat catalase increases expression ISO Silver Nitrate results in increased expression of CAT mRNA CTD PMID:19508889 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Ccna2 cyclin A2 decreases expression ISO Silver Nitrate analog results in decreased expression of CCNA2 mRNA CTD PMID:22831968 NCBI chr 2:123,274,727...123,282,266
Ensembl chr 2:123,275,881...123,282,214
JBrowse link
G Ccnb1 cyclin B1 decreases expression ISO Silver Nitrate analog results in decreased expression of CCNB1 mRNA; Silver Nitrate results in decreased expression of CCNB1 mRNA CTD PMID:22831968 NCBI chr 2:30,782,133...30,791,106
Ensembl chr 2:30,783,915...30,791,221
JBrowse link
G Ccne1 cyclin E1 increases expression ISO Silver Nitrate analog results in increased expression of CCNE1 mRNA; Silver Nitrate results in increased expression of CCNE1 mRNA CTD PMID:22831968 NCBI chr 1:94,485,830...94,495,112
Ensembl chr 1:94,485,832...94,494,980
JBrowse link
G Cd28 Cd28 molecule multiple interactions
affects response to substance
ISO CD28 protein affects the reaction [Silver Nitrate results in decreased activity of FBL protein]
CD28 protein affects the susceptibility to Silver Nitrate
CTD PMID:19077085 NCBI chr 9:67,546,408...67,573,858
Ensembl chr 9:67,546,408...67,571,871
JBrowse link
G Cdc14a cell division cycle 14A increases expression ISO Silver Nitrate analog results in increased expression of CDC14A mRNA CTD PMID:22831968 NCBI chr 2:219,302,577...219,458,345
Ensembl chr 2:219,302,577...219,458,271
JBrowse link
G Cdc25b cell division cycle 25B affects expression ISO Silver Nitrate analog affects the expression of CDC25B mRNA CTD PMID:22831968 NCBI chr 3:123,731,539...123,741,696
Ensembl chr 3:123,731,539...123,741,339
JBrowse link
G Cdc25c cell division cycle 25C affects expression ISO Silver Nitrate analog affects the expression of CDC25C mRNA CTD PMID:22831968 NCBI chr18:27,528,768...27,550,316
Ensembl chr18:27,528,354...27,550,224
JBrowse link
G Cdc45 cell division cycle 45 increases expression ISO Silver Nitrate analog results in increased expression of CDC45 mRNA; Silver Nitrate results in increased expression of CDC45 mRNA CTD PMID:22831968 NCBI chr11:86,328,785...86,354,099
Ensembl chr11:86,329,012...86,358,453
JBrowse link
G Cdc6 cell division cycle 6 increases expression ISO Silver Nitrate analog results in increased expression of CDC6 mRNA; Silver Nitrate results in increased expression of CDC6 mRNA CTD PMID:22831968 NCBI chr10:86,819,477...86,833,301
Ensembl chr10:86,819,472...86,833,402
JBrowse link
G Cdc7 cell division cycle 7 affects expression
increases expression
ISO Silver Nitrate analog affects the expression of CDC7 mRNA
Silver Nitrate results in increased expression of CDC7 mRNA
CTD PMID:22831968 NCBI chr14:3,826,658...3,846,891
Ensembl chr14:3,826,659...3,846,891
JBrowse link
G Cdk1 cyclin-dependent kinase 1 affects expression ISO Silver Nitrate analog affects the expression of CDK1 mRNA CTD PMID:22831968 NCBI chr20:20,576,341...20,591,510
Ensembl chr20:20,576,377...20,591,549
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A increases expression ISO Silver Nitrate results in increased expression of CDKN2A mRNA CTD PMID:22831968 NCBI chr 5:107,823,323...107,832,405
Ensembl chr 5:107,823,330...107,841,175
JBrowse link
G Cdkn2c cyclin-dependent kinase inhibitor 2C affects expression ISO Silver Nitrate analog affects the expression of CDKN2C mRNA CTD PMID:22831968 NCBI chr 5:129,347,731...129,352,886
Ensembl chr 5:129,347,732...129,352,886
JBrowse link
G Cfl1 cofilin 1 multiple interactions ISO CFL1 mRNA promotes the reaction [Silver Nitrate results in increased expression of AURKA protein modified form]; CFL1 mRNA promotes the reaction [Silver Nitrate results in increased expression of AURKC protein modified form]; CFL1 mRNA promotes the reaction [Silver Nitrate results in increased phosphorylation of AURKB protein] CTD PMID:28499611 NCBI chr 1:220,869,805...220,873,337
Ensembl chr 1:220,869,805...220,873,337
JBrowse link
G Chek1 checkpoint kinase 1 increases expression ISO Silver Nitrate analog results in increased expression of CHEK1 mRNA CTD PMID:22831968 NCBI chr 8:39,181,162...39,201,588
Ensembl chr 8:39,181,163...39,243,882
JBrowse link
G Chek2 checkpoint kinase 2 increases expression ISO Silver Nitrate analog results in increased expression of CHEK2 mRNA CTD PMID:22831968 NCBI chr12:51,845,574...51,878,098
Ensembl chr12:51,845,796...51,877,624
JBrowse link
G Dbf4 DBF4 zinc finger increases expression ISO Silver Nitrate analog results in increased expression of DBF4 mRNA; Silver Nitrate results in increased expression of DBF4 mRNA CTD PMID:22831968 NCBI chr 4:22,898,527...22,914,091
Ensembl chr 4:22,898,527...22,914,177
JBrowse link
G Dnaja1 DnaJ heat shock protein family (Hsp40) member A1 increases expression ISO Silver Nitrate analog results in increased expression of DNAJA1 mRNA CTD PMID:22831968 NCBI chr 5:57,028,467...57,039,378
Ensembl chr 5:57,028,467...57,039,378
JBrowse link
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 increases expression ISO Silver Nitrate analog results in increased expression of DNAJB1 mRNA CTD PMID:22831968 NCBI chr19:24,747,178...24,750,919
Ensembl chr19:24,747,178...24,750,919
JBrowse link
G Dnajc19 DnaJ heat shock protein family (Hsp40) member C19 decreases expression ISO Silver Nitrate analog results in decreased expression of DNAJC19 mRNA CTD PMID:22831968 NCBI chr 2:120,503,093...120,531,782
Ensembl chr 2:120,504,130...120,531,782
JBrowse link
G E2f1 E2F transcription factor 1 increases expression ISO Silver Nitrate analog results in increased expression of E2F1 mRNA CTD PMID:22831968 NCBI chr 3:150,062,895...150,073,721
Ensembl chr 3:150,047,826...150,073,721
JBrowse link
G E2f2 E2F transcription factor 2 increases expression ISO Silver Nitrate analog results in increased expression of E2F2 mRNA CTD PMID:22831968 NCBI chr 5:154,516,611...154,540,228
Ensembl chr 5:154,522,119...154,540,265
JBrowse link
G E2f3 E2F transcription factor 3 increases expression ISO Silver Nitrate analog results in increased expression of E2F3 mRNA CTD PMID:22831968 NCBI chr17:36,334,136...36,408,831
Ensembl chr17:36,334,147...36,408,831
JBrowse link
G E2f4 E2F transcription factor 4 increases expression ISO Silver Nitrate results in increased expression of E2F4 mRNA CTD PMID:22831968 NCBI chr19:37,252,828...37,260,239
Ensembl chr19:37,252,843...37,260,239
JBrowse link
G E2f5 E2F transcription factor 5 increases expression ISO Silver Nitrate results in increased expression of E2F5 mRNA CTD PMID:22831968 NCBI chr 2:88,350,764...88,366,913
Ensembl chr 2:88,351,361...88,366,115
JBrowse link
G Fbl fibrillarin multiple interactions
decreases activity
ISO CD28 protein affects the reaction [Silver Nitrate results in decreased activity of FBL protein]; IFNG protein affects the reaction [Silver Nitrate results in decreased activity of FBL protein]; IL4 protein affects the reaction [Silver Nitrate results in decreased activity of FBL protein]; IL6 protein affects the reaction [Silver Nitrate results in decreased activity of FBL protein] CTD PMID:19077085 NCBI chr 1:85,103,519...85,112,619
Ensembl chr 1:85,103,519...85,112,619
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression ISO Silver Nitrate results in increased expression of FOS mRNA CTD PMID:10362023 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit decreases expression ISO Silver Nitrate results in decreased expression of FOSB mRNA CTD PMID:27180073 NCBI chr 1:80,214,691...80,221,417
Ensembl chr 1:80,214,494...80,221,710
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase decreases activity EXP Silver Nitrate results in decreased activity of G6PD protein CTD PMID:28557068 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit decreases expression ISO Silver Nitrate results in decreased expression of GCLC mRNA CTD PMID:19733233 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Gpx1 glutathione peroxidase 1 increases expression ISO Silver Nitrate results in increased expression of GPX1 mRNA CTD PMID:19508889 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G Gpx7 glutathione peroxidase 7 increases expression ISO Silver Nitrate results in increased expression of GPX7 mRNA CTD PMID:27180073 NCBI chr 5:128,001,766...128,009,610
Ensembl chr 5:128,001,761...128,009,735
JBrowse link
G H1f5 H1.5 linker histone, cluster member decreases expression ISO Silver Nitrate analog results in decreased expression of H1-5 mRNA; Silver Nitrate results in decreased expression of H1-5 mRNA CTD PMID:22831968 NCBI chr17:44,766,313...44,766,981
Ensembl chr17:44,766,313...44,766,981
JBrowse link
G H4f3 H1.3 linker histone, cluster member decreases expression ISO Silver Nitrate analog results in decreased expression of H1-3 mRNA CTD PMID:22831968 NCBI chr17:43,797,711...43,798,450
Ensembl chr17:43,797,721...43,798,383
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression
ISO Silver Nitrate promotes the reaction [HSF1 protein binds to HMOX1 promoter]
Silver Nitrate results in increased expression of HMOX1 mRNA
CTD PMID:17244614, PMID:27180073 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hsf1 heat shock transcription factor 1 multiple interactions
increases activity
ISO Silver Nitrate promotes the reaction [HSF1 protein binds to HMOX1 promoter]; Silver Nitrate promotes the reaction [HSF1 protein binds to HSPA1A enhancer]; Silver Nitrate promotes the reaction [HSF1 protein binds to HSPA1A promoter]
Silver Nitrate results in increased activity of HSF1 protein
CTD PMID:16460681, PMID:17244614 NCBI chr 7:117,538,523...117,565,478
Ensembl chr 7:117,538,523...117,565,478
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 increases expression ISO Silver Nitrate analog results in increased expression of HSP90AA1 mRNA CTD PMID:22831968 NCBI chr 6:135,107,262...135,112,793
Ensembl chr 6:135,107,271...135,112,775
JBrowse link
G Hspa12a heat shock protein family A (Hsp70) member 12A decreases expression ISO Silver Nitrate analog results in decreased expression of HSPA12A mRNA CTD PMID:22831968 NCBI chr 1:279,946,809...280,104,366
Ensembl chr 1:279,946,811...280,015,358
JBrowse link
G Hspa12b heat shock protein family A (Hsp70) member 12B increases expression ISO Silver Nitrate analog results in increased expression of HSPA12B mRNA CTD PMID:22831968 NCBI chr 3:123,670,219...123,688,640
Ensembl chr 3:123,670,275...123,687,691
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A multiple interactions
increases expression
ISO Silver Nitrate promotes the reaction [HSF1 protein binds to HSPA1A enhancer]; Silver Nitrate promotes the reaction [HSF1 protein binds to HSPA1A promoter]
Silver Nitrate results in increased expression of HSPA1A mRNA
CTD PMID:16460681, PMID:17244614, PMID:27180073 NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779
JBrowse link
G Hspb11 heat shock protein family B (small), member 11 decreases expression ISO Silver Nitrate analog results in decreased expression of HSPB11 mRNA CTD PMID:22831968 NCBI chr 5:126,856,128...126,882,913
Ensembl chr 5:126,856,705...126,882,909
JBrowse link
G Hspb9 heat shock protein family B (small) member 9 increases expression ISO Silver Nitrate analog results in increased expression of HSPB9 mRNA CTD PMID:22831968 NCBI chr10:88,620,655...88,621,300
Ensembl chr10:88,620,655...88,621,300
JBrowse link
G Hsph1 heat shock protein family H (Hsp110) member 1 increases expression ISO Silver Nitrate analog results in increased expression of HSPH1 mRNA CTD PMID:22831968 NCBI chr12:6,322,685...6,341,898
Ensembl chr12:6,322,668...6,341,902
JBrowse link
G Ifng interferon gamma affects response to substance
multiple interactions
ISO IFNG protein affects the susceptibility to Silver Nitrate
IFNG protein affects the reaction [Silver Nitrate results in decreased activity of FBL protein]
CTD PMID:19077085 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Il1b interleukin 1 beta increases expression ISO Silver Nitrate results in increased expression of IL1B protein CTD PMID:25527144 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il4 interleukin 4 affects response to substance
multiple interactions
ISO IL4 protein affects the susceptibility to Silver Nitrate
IL4 protein affects the reaction [Silver Nitrate results in decreased activity of FBL protein]
CTD PMID:19077085 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Il6 interleukin 6 affects response to substance
multiple interactions
ISO IL6 protein affects the susceptibility to Silver Nitrate
IL6 protein affects the reaction [Silver Nitrate results in decreased activity of FBL protein]
CTD PMID:19077085 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Kitlg KIT ligand increases expression ISO Silver Nitrate results in increased expression of KITLG mRNA CTD PMID:22831968 NCBI chr 7:42,269,784...42,351,054
Ensembl chr 7:42,269,784...42,351,054
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation ISO Silver Nitrate results in increased phosphorylation of MAPK1 protein CTD PMID:27624343 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation ISO Silver Nitrate results in increased phosphorylation of MAPK3 protein CTD PMID:27624343 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mcm3 minichromosome maintenance complex component 3 decreases expression ISO Silver Nitrate analog results in decreased expression of MCM3 mRNA CTD PMID:22831968 NCBI chr 9:26,914,057...26,932,201
Ensembl chr 9:26,914,057...26,932,201
JBrowse link
G Mcm4 minichromosome maintenance complex component 4 increases expression ISO Silver Nitrate results in increased expression of MCM4 mRNA CTD PMID:22831968 NCBI chr11:89,511,191...89,524,892
Ensembl chr11:89,511,191...89,524,892
JBrowse link
G Mcm6 minichromosome maintenance complex component 6 increases expression ISO Silver Nitrate results in increased expression of MCM6 mRNA CTD PMID:22831968 NCBI chr13:45,042,882...45,068,073
Ensembl chr13:45,042,882...45,068,077
JBrowse link
G Mt1 metallothionein 1 multiple interactions
increases expression
ISO MTF1 mutant form inhibits the reaction [Silver Nitrate results in increased expression of MT1A mRNA]
Silver Nitrate results in increased expression of MT1 mRNA
Silver Nitrate analog results in increased expression of MT1A mRNA; Silver Nitrate results in increased expression of MT1A mRNA
CTD PMID:19733233, PMID:22831968, PMID:23333424, PMID:27624343 NCBI chr19:11,301,991...11,303,007
Ensembl chr17:78,793,336...78,793,724
JBrowse link
G Mt2A metallothionein 2A increases expression ISO Silver Nitrate results in increased expression of MT2A mRNA
Silver Nitrate results in increased expression of MT2 mRNA
CTD PMID:10362023, PMID:20491607, PMID:23333424, PMID:27180073, PMID:27624343 NCBI chr19:11,307,966...11,308,740
Ensembl chr19:11,307,967...11,308,740
JBrowse link
G Mt3 metallothionein 3 increases expression ISO Silver Nitrate analog results in increased expression of MT3 mRNA CTD PMID:22831968 NCBI chr19:11,324,708...11,326,112
Ensembl chr19:11,324,698...11,326,139
JBrowse link
G Mt4 metallothionein 4 increases expression ISO Silver Nitrate analog results in increased expression of MT4 mRNA; Silver Nitrate results in increased expression of MT4 mRNA CTD PMID:22831968 NCBI chr19:11,339,767...11,341,863
Ensembl chr19:11,339,767...11,341,863
JBrowse link
G Mtf1 metal-regulatory transcription factor 1 multiple interactions
increases activity
ISO MTF1 mutant form inhibits the reaction [Silver Nitrate results in increased expression of MT1A mRNA]; MTF1 mutant form inhibits the reaction [Silver Nitrate results in increased expression of SLC30A1 mRNA]
Silver Nitrate results in increased activity of MTF1 protein
CTD PMID:19733233 NCBI chr 5:142,797,340...142,843,896
Ensembl chr 5:142,797,366...142,842,122
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 decreases expression
increases activity
ISO Silver Nitrate results in decreased expression of NFE2L2 mRNA
Silver Nitrate results in increased activity of NFE2L2 protein
CTD PMID:19733233, PMID:23872425 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Orc6 origin recognition complex, subunit 6 increases expression ISO Silver Nitrate results in increased expression of ORC6 mRNA CTD PMID:22831968 NCBI chr19:27,457,541...27,464,804
Ensembl chr19:27,457,474...27,464,805
JBrowse link
G Pcna proliferating cell nuclear antigen increases expression ISO Silver Nitrate analog results in increased expression of PCNA mRNA; Silver Nitrate results in increased expression of PCNA mRNA CTD PMID:22831968 NCBI chr 3:124,880,698...124,884,570
Ensembl chr 3:124,880,698...124,884,570
JBrowse link
G Plk1 polo-like kinase 1 decreases expression ISO Silver Nitrate analog results in decreased expression of PLK1 mRNA CTD PMID:22831968 NCBI chr 1:192,115,990...192,125,969
Ensembl chr 1:192,115,966...192,125,989
JBrowse link
G Pttg1 PTTG1 regulator of sister chromatid separation, securin increases expression
affects expression
ISO Silver Nitrate results in increased expression of PTTG1 mRNA
Silver Nitrate analog affects the expression of PTTG1 mRNA
CTD PMID:22831968 NCBI chr10:29,014,332...29,026,088
Ensembl chr10:29,020,049...29,026,002
JBrowse link
G Rbl1 RB transcriptional corepressor like 1 increases expression ISO Silver Nitrate analog results in increased expression of RBL1 mRNA; Silver Nitrate results in increased expression of RBL1 mRNA CTD PMID:22831968 NCBI chr 3:153,263,692...153,321,351
Ensembl chr 3:153,263,692...153,321,352
JBrowse link
G Rbl2 RB transcriptional corepressor like 2 increases expression ISO Silver Nitrate analog results in increased expression of RBL2 mRNA; Silver Nitrate results in increased expression of RBL2 mRNA CTD PMID:22831968 NCBI chr19:17,300,088...17,346,865
Ensembl chr19:17,300,089...17,346,808
JBrowse link
G Skp2 S-phase kinase associated protein 2 increases expression ISO Silver Nitrate analog results in increased expression of SKP2 mRNA CTD PMID:22831968 NCBI chr 2:58,506,146...58,534,211
Ensembl chr 2:58,506,151...58,534,211
JBrowse link
G Slc30a1 solute carrier family 30 member 1 multiple interactions
increases expression
ISO MTF1 mutant form inhibits the reaction [Silver Nitrate results in increased expression of SLC30A1 mRNA] CTD PMID:19733233 NCBI chr13:110,677,810...110,681,683
Ensembl chr13:110,677,810...110,681,683
JBrowse link
G Slc31a1 solute carrier family 31 member 1 increases expression ISO Silver Nitrate results in increased expression of SLC31A1 mRNA CTD PMID:24132751 NCBI chr 5:78,222,504...78,249,358
Ensembl chr 5:78,222,504...78,249,358
JBrowse link
G Smad2 SMAD family member 2 decreases expression
increases expression
ISO Silver Nitrate analog results in decreased expression of SMAD2 mRNA
Silver Nitrate results in increased expression of SMAD2 mRNA
CTD PMID:22831968 NCBI chr18:72,550,107...72,612,078
Ensembl chr18:72,550,219...72,612,078
JBrowse link
G Smad3 SMAD family member 3 decreases expression
increases expression
ISO Silver Nitrate analog results in decreased expression of SMAD3 mRNA
Silver Nitrate results in increased expression of SMAD3 mRNA
CTD PMID:22831968 NCBI chr 8:68,569,530...68,678,349
Ensembl chr 8:68,569,530...68,678,349
JBrowse link
G Sod1 superoxide dismutase 1 increases expression ISO Silver Nitrate results in increased expression of SOD1 mRNA CTD PMID:19508889 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Sp1 Sp1 transcription factor increases expression ISO Silver Nitrate results in increased expression of SP1 mRNA CTD PMID:24132751 NCBI chr 7:144,014,173...144,044,635
Ensembl chr 7:144,014,173...144,044,629
JBrowse link
G Tfdp1 transcription factor Dp-1 increases expression ISO Silver Nitrate analog results in increased expression of TFDP1 mRNA CTD PMID:22831968 NCBI chr16:81,088,642...81,127,244
Ensembl chr16:81,089,292...81,127,257
JBrowse link
G Tfdp2 transcription factor Dp-2 increases expression ISO Silver Nitrate analog results in increased expression of TFDP2 mRNA CTD PMID:22831968 NCBI chr 8:104,040,795...104,181,228
Ensembl chr 8:104,040,934...104,176,446
JBrowse link
G Tp53 tumor protein p53 decreases expression ISO Silver Nitrate analog results in decreased expression of TP53 mRNA CTD PMID:22831968 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Tpo thyroid peroxidase increases expression ISO Silver Nitrate results in increased expression of TPO mRNA CTD PMID:27180073 NCBI chr 6:49,020,918...49,089,855
Ensembl chr 6:49,021,044...49,089,855
JBrowse link
sodium nitrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acadl acyl-CoA dehydrogenase, long chain multiple interactions ISO sodium nitrate inhibits the reaction [Doxorubicin results in increased expression of ACADL protein] CTD PMID:21251210 NCBI chr 9:73,833,368...73,871,857
Ensembl chr 9:73,833,388...73,871,888
JBrowse link
G Actc1 actin, alpha, cardiac muscle 1 multiple interactions ISO sodium nitrate inhibits the reaction [Doxorubicin results in increased expression of ACTC1 protein] CTD PMID:21251210 NCBI chr 3:105,507,403...105,512,939
Ensembl chr 3:105,507,403...105,512,939
JBrowse link
G Afp alpha-fetoprotein multiple interactions ISO sodium nitrate inhibits the reaction [Doxorubicin results in decreased expression of AFP protein] CTD PMID:21251210 NCBI chr14:19,141,755...19,159,919
Ensembl chr14:19,141,755...19,159,923
JBrowse link
G Atp5f1b ATP synthase F1 subunit beta multiple interactions ISO sodium nitrate inhibits the reaction [Doxorubicin results in increased expression of ATP5B protein] CTD PMID:21251210 NCBI chr 7:2,504,708...2,511,748
Ensembl chr 7:2,504,695...2,511,749
JBrowse link
G Atp5pd ATP synthase peripheral stalk subunit d multiple interactions ISO sodium nitrate inhibits the reaction [Doxorubicin results in increased expression of ATP5H protein] CTD PMID:21251210 NCBI chr10:103,967,340...103,972,552
Ensembl chr10:103,967,312...103,972,668
JBrowse link
G Cacna2d1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 increases expression ISO sodium nitrate results in increased expression of CACNA2D1 protein CTD PMID:22687611 NCBI chr 4:15,706,974...16,130,848
Ensembl chr 4:15,710,417...16,130,848
JBrowse link
G Casq1 calsequestrin 1 increases expression ISO sodium nitrate results in increased expression of CASQ1 protein CTD PMID:22687611 NCBI chr13:90,592,676...90,602,365
Ensembl chr13:90,592,681...90,602,365
JBrowse link
G Cat catalase decreases activity EXP sodium nitrate results in decreased activity of CAT protein CTD PMID:24740966 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cox4i1 cytochrome c oxidase subunit 4i1 multiple interactions ISO sodium nitrate inhibits the reaction [Doxorubicin results in increased expression of COX4I1 protein] CTD PMID:21251210 NCBI chr19:54,245,958...54,252,198
Ensembl chr19:54,245,950...54,252,225
JBrowse link
G Cryab crystallin, alpha B multiple interactions ISO sodium nitrate inhibits the reaction [Doxorubicin results in increased expression of CRYAB protein] CTD PMID:21251210 NCBI chr 8:55,178,543...55,182,546
Ensembl chr 8:55,178,289...55,182,545
JBrowse link
G Fabp3 fatty acid binding protein 3 multiple interactions ISO sodium nitrate inhibits the reaction [Doxorubicin results in increased expression of FABP3 protein] CTD PMID:21251210 NCBI chr 5:148,528,854...148,535,597
Ensembl chr 5:148,528,725...148,535,565
JBrowse link
G Fth1 ferritin heavy chain 1 multiple interactions ISO sodium nitrate inhibits the reaction [Doxorubicin results in decreased expression of FTH1 protein] CTD PMID:21251210 NCBI chr 1:226,030,940...226,033,228
Ensembl chr 1:226,030,938...226,033,228
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase decreases activity EXP sodium nitrate results in decreased activity of G6PD protein CTD PMID:19922758 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 multiple interactions ISO sodium nitrate inhibits the reaction [Doxorubicin results in increased expression of GOT1 protein] CTD PMID:21251210 NCBI chr 1:263,246,248...263,269,762
Ensembl chr 1:263,246,248...263,269,762
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions ISO [Quercetin co-treated with sodium nitrate] results in increased activity of GSR protein CTD PMID:24860958 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Idh3a isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha multiple interactions ISO sodium nitrate inhibits the reaction [Doxorubicin results in increased expression of IDH3A protein] CTD PMID:21251210 NCBI chr 8:59,164,601...59,183,899
Ensembl chr 8:59,164,572...59,183,908
JBrowse link
G Ldhc lactate dehydrogenase C decreases activity EXP sodium nitrate results in decreased activity of LDHC protein CTD PMID:19922758 NCBI chr 1:102,914,875...102,931,843
Ensembl chr 1:102,915,191...102,931,839
JBrowse link
G Mb myoglobin multiple interactions ISO sodium nitrate inhibits the reaction [Doxorubicin results in increased expression of MB protein] CTD PMID:21251210 NCBI chr 7:118,101,633...118,108,864
Ensembl chr 7:118,101,634...118,108,864
JBrowse link
G Mpo myeloperoxidase multiple interactions EXP sodium nitrate inhibits the reaction [Diclofenac results in increased activity of MPO protein] CTD PMID:17275683 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
JBrowse link
G Muc6 mucin 6, oligomeric mucus/gel-forming increases expression EXP sodium nitrate results in increased expression of MUC6 mRNA CTD PMID:17275683 NCBI chr 1:214,608,453...214,630,524
Ensembl chr 1:214,608,704...214,629,938
JBrowse link
G Myh6 myosin heavy chain 6 multiple interactions ISO sodium nitrate inhibits the reaction [Doxorubicin results in decreased expression of MYH6 protein] CTD PMID:21251210 NCBI chr15:33,605,653...33,629,730
Ensembl chr15:33,605,654...33,629,699
JBrowse link
G Myl2 myosin light chain 2 multiple interactions ISO [sodium nitrate co-treated with Doxorubicin] results in decreased expression of MYL2 protein; sodium nitrate inhibits the reaction [Doxorubicin results in increased expression of MYL2 protein] CTD PMID:21251210 NCBI chr12:39,951,863...39,959,065
Ensembl chr12:39,951,987...39,958,239
JBrowse link
G Myl3 myosin light chain 3 multiple interactions ISO sodium nitrate inhibits the reaction [Doxorubicin results in increased expression of MYL3 protein] CTD PMID:21251210 NCBI chr 8:119,030,852...119,036,996
Ensembl chr 8:119,030,875...119,036,996
JBrowse link
G Myoz2 myozenin 2 multiple interactions ISO sodium nitrate inhibits the reaction [Doxorubicin results in increased expression of MYOZ2 protein] CTD PMID:21251210 NCBI chr 2:227,180,887...227,207,629
Ensembl chr 2:227,180,886...227,207,635
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions EXP sodium nitrate inhibits the reaction [Diclofenac results in increased expression of NOS2 mRNA] CTD PMID:17275683 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nos3 nitric oxide synthase 3 multiple interactions ISO sodium nitrate inhibits the reaction [NOS3 gene mutant form results in increased abundance of Triglycerides] CTD PMID:20876122 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410
JBrowse link
G Pkm pyruvate kinase M1/2 multiple interactions ISO sodium nitrate inhibits the reaction [Doxorubicin results in increased expression of PKM protein] CTD PMID:21251210 NCBI chr 8:64,480,963...64,502,957
Ensembl chr 8:64,481,172...64,502,722
JBrowse link
G Prdx3 peroxiredoxin 3 multiple interactions ISO sodium nitrate inhibits the reaction [Doxorubicin results in increased expression of PRDX3 protein] CTD PMID:21251210 NCBI chr 1:282,238,774...282,251,193
Ensembl chr 1:282,238,773...282,251,257
JBrowse link
G Prdx5 peroxiredoxin 5 increases expression
multiple interactions
ISO sodium nitrate results in increased expression of PRDX5 protein
sodium nitrate inhibits the reaction [Doxorubicin results in decreased expression of PRDX5 protein]
CTD PMID:21251210, PMID:22484629 NCBI chr 1:222,164,462...222,167,447
Ensembl chr 1:222,164,462...222,167,447
JBrowse link
G Pygb glycogen phosphorylase B multiple interactions ISO sodium nitrate inhibits the reaction [Doxorubicin results in decreased expression of PYGB protein] CTD PMID:21251210 NCBI chr 3:146,581,063...146,629,504
Ensembl chr 3:146,582,752...146,634,535
JBrowse link
G Pygm glycogen phosphorylase, muscle associated multiple interactions ISO sodium nitrate inhibits the reaction [Doxorubicin results in increased expression of PYGM protein] CTD PMID:21251210 NCBI chr 1:221,756,325...221,771,142
Ensembl chr 1:221,756,286...221,771,143
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions ISO sodium nitrate inhibits the reaction [Doxorubicin results in increased expression of SOD2 protein] CTD PMID:21251210 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Srl sarcalumenin multiple interactions ISO sodium nitrate inhibits the reaction [Doxorubicin results in increased expression of SRL protein] CTD PMID:21251210 NCBI chr10:11,240,135...11,284,325
Ensembl chr10:11,240,138...11,284,332
JBrowse link
G Suclg2 succinate-CoA ligase GDP-forming subunit beta multiple interactions ISO sodium nitrate inhibits the reaction [Doxorubicin results in decreased expression of SUCLG2 protein] CTD PMID:21251210 NCBI chr 4:127,552,100...127,824,970
Ensembl chr 4:127,552,101...127,824,970
JBrowse link
G Uqcrc1 ubiquinol-cytochrome c reductase core protein 1 multiple interactions ISO sodium nitrate inhibits the reaction [Doxorubicin results in increased expression of UQCRC1 protein] CTD PMID:21251210 NCBI chr 8:117,679,328...117,691,073
Ensembl chr 8:117,679,278...117,691,071
JBrowse link
G Xdh xanthine dehydrogenase increases metabolic processing ISO XDH protein results in increased metabolism of sodium nitrate CTD PMID:20142047 NCBI chr 6:25,149,570...25,211,273
Ensembl chr 6:25,149,235...25,211,494
JBrowse link
G Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta multiple interactions ISO sodium nitrate inhibits the reaction [Doxorubicin results in decreased expression of YWHAZ protein] CTD PMID:21251210 NCBI chr 7:75,573,553...75,598,295
Ensembl chr 7:75,574,967...75,597,276
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19785
    chemical entity 19785
      molecular entity 19782
        inorganic molecular entity 19454
          inorganic nitrate salt 327
            ammonium nitrate + 1
            ammonium nitrate phosphate 0
            cadmium nitrate + 3
            cadmium nitrate tetrahydrate 0
            calcium nitrate + 0
            calcium nitrate tetrahydrate 0
            chromium trinitrate + 43
            chromium trinitrate heptahydrate 0
            cobalt dinitrate + 0
            cobalt dinitrate hexahydrate 0
            cobalt trinitrate 0
            copper(II) nitrate 3
            lead nitrate 176
            lithium nitrate 0
            magnesium nitrate 0
            potassium nitrate 11
            silver(1+) nitrate 85
            sodium nitrate 37
Path 2
Term Annotations click to browse term
  CHEBI ontology 19785
    subatomic particle 19782
      composite particle 19782
        hadron 19782
          baryon 19782
            nucleon 19782
              atomic nucleus 19782
                atom 19782
                  main group element atom 19670
                    p-block element atom 19670
                      chalcogen 19360
                        oxygen atom 19321
                          oxygen molecular entity 19321
                            oxide 11576
                              oxoanion 8668
                                pnictogen oxoanion 3548
                                  nitrogen oxoanion 340
                                    nitrate 327
                                      nitrate salt 327
                                        inorganic nitrate salt 327
                                          ammonium nitrate + 1
                                          ammonium nitrate phosphate 0
                                          cadmium nitrate + 3
                                          cadmium nitrate tetrahydrate 0
                                          calcium nitrate + 0
                                          calcium nitrate tetrahydrate 0
                                          chromium trinitrate + 43
                                          chromium trinitrate heptahydrate 0
                                          cobalt dinitrate + 0
                                          cobalt dinitrate hexahydrate 0
                                          cobalt trinitrate 0
                                          copper(II) nitrate 3
                                          lead nitrate 176
                                          lithium nitrate 0
                                          magnesium nitrate 0
                                          potassium nitrate 11
                                          silver(1+) nitrate 85
                                          sodium nitrate 37
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.