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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:nitrate salt
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Accession:CHEBI:51082 term browser browse the term


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ammonium nitrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il1b interleukin 1 beta increases expression ISO ammonium nitrate results in increased expression of IL1B protein CTD PMID:29953848 NCBI chr 2:129,364,569...129,371,164
Ensembl chr 2:129,364,570...129,371,139
JBrowse link
cadmium nitrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cav1 caveolin 1, caveolae protein decreases expression ISO cadmium nitrate results in decreased expression of CAV1 protein CTD PMID:19061949 NCBI chr 6:17,306,335...17,341,328
Ensembl chr 6:17,306,335...17,341,452
JBrowse link
G G6pdx glucose-6-phosphate dehydrogenase X-linked decreases activity ISO cadmium nitrate results in decreased activity of G6PD protein CTD PMID:28557068 NCBI chr  X:74,409,483...74,428,880
Ensembl chr  X:74,409,483...74,429,194
JBrowse link
G Itgb4 integrin beta 4 decreases expression ISO cadmium nitrate results in decreased expression of ITGB4 protein CTD PMID:19061949 NCBI chr11:115,974,725...116,008,412
Ensembl chr11:115,974,709...116,008,412
JBrowse link
chromium trinitrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahsg alpha-2-HS-glycoprotein decreases expression EXP chromium nitrate results in decreased expression of AHSG protein CTD PMID:23618972 NCBI chr16:22,892,015...22,899,451
Ensembl chr16:22,891,277...22,899,449
JBrowse link
G Aldh1l2 aldehyde dehydrogenase 1 family, member L2 increases expression EXP chromium nitrate results in increased expression of ALDH1L2 protein CTD PMID:22144121 NCBI chr10:83,487,447...83,534,146
Ensembl chr10:83,487,450...83,534,140
JBrowse link
G Apcs serum amyloid P-component increases expression EXP chromium nitrate results in increased expression of APCS protein CTD PMID:23618972 NCBI chr 1:172,893,961...172,895,054
Ensembl chr 1:172,893,961...172,895,041
JBrowse link
G Apoa1 apolipoprotein A-I decreases expression EXP chromium nitrate results in decreased expression of APOA1 protein CTD PMID:23618972 NCBI chr 9:46,228,630...46,230,469
Ensembl chr 9:46,228,580...46,230,466
JBrowse link
G Atp5b ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit increases expression EXP chromium nitrate results in increased expression of ATP5B protein CTD PMID:19771553 NCBI chr10:128,083,307...128,090,388
Ensembl chr10:128,083,273...128,090,391
JBrowse link
G Bckdhb branched chain ketoacid dehydrogenase E1, beta polypeptide decreases expression EXP chromium nitrate results in decreased expression of BCKDHB protein CTD PMID:22144121 NCBI chr 9:83,925,111...84,124,240
Ensembl chr 9:83,925,145...84,124,240
JBrowse link
G Cct5 chaperonin containing Tcp1, subunit 5 (epsilon) decreases expression EXP chromium nitrate results in decreased expression of CCT5 protein CTD PMID:22144121 NCBI chr15:31,590,800...31,601,846
Ensembl chr15:31,590,800...31,601,804
JBrowse link
G Ces1c carboxylesterase 1C decreases expression EXP chromium nitrate results in decreased expression of CES1C protein CTD PMID:23618972 NCBI chr 8:93,099,015...93,131,283
Ensembl chr 8:93,099,015...93,131,283
JBrowse link
G Ces1d carboxylesterase 1D increases expression EXP chromium nitrate results in increased expression of CES1D protein CTD PMID:22144121 NCBI chr 8:93,166,072...93,197,804
Ensembl chr 8:93,166,068...93,197,838
JBrowse link
G Dbt dihydrolipoamide branched chain transacylase E2 increases expression EXP chromium nitrate results in increased expression of DBT protein CTD PMID:22144121 NCBI chr 3:116,513,070...116,549,981
Ensembl chr 3:116,513,070...116,549,981
JBrowse link
G Ddah1 dimethylarginine dimethylaminohydrolase 1 decreases expression EXP chromium nitrate results in decreased expression of DDAH1 protein CTD PMID:22144121 NCBI chr 3:145,758,692...145,894,277
Ensembl chr 3:145,758,675...145,894,277
JBrowse link
G Ech1 enoyl coenzyme A hydratase 1, peroxisomal increases expression EXP chromium nitrate results in increased expression of ECH1 protein CTD PMID:22144121 NCBI chr 7:28,825,338...28,832,239
Ensembl chr 7:28,825,217...28,832,247
JBrowse link
G Fbp1 fructose bisphosphatase 1 increases expression EXP chromium nitrate results in increased expression of FBP1 protein CTD PMID:22144121 NCBI chr13:62,864,753...62,888,298
Ensembl chr13:62,864,753...62,888,282
JBrowse link
G Fgb fibrinogen beta chain increases expression EXP chromium nitrate results in increased expression of FGB protein CTD PMID:23618972 NCBI chr 3:83,042,246...83,049,863
Ensembl chr 3:83,040,141...83,049,863
JBrowse link
G Fgg fibrinogen gamma chain increases expression EXP chromium nitrate results in increased expression of FGG protein CTD PMID:23618972 NCBI chr 3:83,007,724...83,015,056
Ensembl chr 3:83,007,724...83,015,049
JBrowse link
G Fkrp fukutin related protein increases expression EXP chromium nitrate results in increased expression of FKRP protein CTD PMID:23618972 NCBI chr 7:16,809,267...16,816,732
Ensembl chr 7:16,809,246...16,816,732
JBrowse link
G Gc vitamin D binding protein decreases expression EXP chromium nitrate results in decreased expression of GC protein CTD PMID:23618972 NCBI chr 5:89,417,511...89,457,898
Ensembl chr 5:89,417,522...89,457,898
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression ISO chromium nitrate results in increased expression of GCLC mRNA CTD PMID:20491607 NCBI chr 9:77,754,535...77,794,489
Ensembl chr 9:77,754,535...77,794,485
JBrowse link
G Haao 3-hydroxyanthranilate 3,4-dioxygenase increases expression EXP chromium nitrate results in increased expression of HAAO protein CTD PMID:22144121 NCBI chr17:83,831,348...83,848,981
Ensembl chr17:83,831,156...83,847,963
JBrowse link
G Hacl1 2-hydroxyacyl-CoA lyase 1 increases expression EXP chromium nitrate results in increased expression of HACL1 protein CTD PMID:22144121 NCBI chr14:31,607,226...31,640,965
Ensembl chr14:31,598,730...31,641,286
JBrowse link
G Hibadh 3-hydroxyisobutyrate dehydrogenase increases expression EXP chromium nitrate results in increased expression of HIBADH protein CTD PMID:22144121 NCBI chr 6:52,546,230...52,640,300
Ensembl chr 6:52,546,228...52,640,389
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO chromium nitrate results in increased expression of HMOX1 mRNA CTD PMID:20491607 NCBI chr 8:75,093,618...75,100,593
Ensembl chr 8:75,093,621...75,100,589
JBrowse link
G Hspd1 heat shock protein 1 (chaperonin) increases expression EXP chromium nitrate results in increased expression of HSPD1 protein CTD PMID:19771553 NCBI chr 1:55,077,833...55,088,243
Ensembl chr 1:55,077,835...55,088,243
JBrowse link
G Khk ketohexokinase decreases expression EXP chromium nitrate results in decreased expression of KHK protein CTD PMID:22144121 NCBI chr 5:30,921,436...30,931,248
Ensembl chr 5:30,921,431...30,931,248
JBrowse link
G Kng2 kininogen 2 increases expression EXP chromium nitrate results in increased expression of KNG1 protein CTD PMID:23618972 NCBI chr16:22,985,852...23,029,101
Ensembl chr16:22,985,854...23,029,482
JBrowse link
G Krt10 keratin 10 increases expression EXP chromium nitrate results in increased expression of KRT10 protein CTD PMID:19771553 NCBI chr11:99,385,254...99,397,449
Ensembl chr11:99,385,254...99,389,364
JBrowse link
G Krt16 keratin 16 increases expression EXP chromium nitrate results in increased expression of KRT16 protein CTD PMID:19771553 NCBI chr11:100,246,091...100,248,902
Ensembl chr11:100,246,091...100,248,902
JBrowse link
G Krt17 keratin 17 increases expression EXP chromium nitrate results in increased expression of KRT17 protein CTD PMID:19771553 NCBI chr11:100,256,215...100,261,029
Ensembl chr11:100,256,217...100,261,029
JBrowse link
G Krt18 keratin 18 decreases expression EXP chromium nitrate results in decreased expression of KRT18 protein CTD PMID:22144121 NCBI chr15:102,028,216...102,032,026
Ensembl chr15:102,028,180...102,032,027
JBrowse link
G Krt25 keratin 25 increases expression EXP chromium nitrate results in increased expression of KRT25 protein CTD PMID:19771553 NCBI chr11:99,315,516...99,322,951
Ensembl chr11:99,315,516...99,322,951
JBrowse link
G Krt27 keratin 27 increases expression EXP chromium nitrate results in increased expression of KRT27 protein CTD PMID:19771553 NCBI chr11:99,345,565...99,351,118
Ensembl chr11:99,345,565...99,351,104
JBrowse link
G Mdh1 malate dehydrogenase 1, NAD (soluble) increases expression EXP chromium nitrate results in increased expression of MDH1 protein CTD PMID:22144121 NCBI chr11:21,556,692...21,571,934
Ensembl chr11:21,556,692...21,572,367
JBrowse link
G Mt2 metallothionein 2 increases expression ISO chromium nitrate results in increased expression of MT2A mRNA CTD PMID:20491607 NCBI chr 8:94,172,618...94,173,567
Ensembl chr 8:94,172,664...94,173,568
JBrowse link
G Park7 Parkinson disease (autosomal recessive, early onset) 7 increases expression EXP chromium nitrate results in increased expression of PARK7 protein CTD PMID:22144121 NCBI chr 4:150,897,133...150,909,921
Ensembl chr 4:150,897,133...150,914,437
JBrowse link
G Pcca propionyl-Coenzyme A carboxylase, alpha polypeptide increases expression EXP chromium nitrate results in increased expression of PCCA protein CTD PMID:22144121 NCBI chr14:122,484,365...122,889,944
Ensembl chr14:122,534,324...122,891,100
JBrowse link
G Pdhb pyruvate dehydrogenase (lipoamide) beta decreases expression EXP chromium nitrate results in decreased expression of PDHB protein CTD PMID:22144121 NCBI chr14:8,165,991...8,173,303
Ensembl chr14:8,165,996...8,173,025
JBrowse link
G Phb prohibitin decreases expression EXP chromium nitrate results in decreased expression of PHB protein CTD PMID:22144121 NCBI chr11:95,666,957...95,680,773
Ensembl chr11:95,666,957...95,680,773
JBrowse link
G Rgn regucalcin decreases expression EXP chromium nitrate results in decreased expression of RGN protein CTD PMID:22144121 NCBI chr  X:20,549,766...20,562,089
Ensembl chr  X:20,549,787...20,562,089
JBrowse link
G Rplp0 ribosomal protein, large, P0 decreases expression EXP chromium nitrate results in decreased expression of RPLP0 protein CTD PMID:22144121 NCBI chr 5:115,559,467...115,563,729
Ensembl chr 5:115,559,467...115,563,727
JBrowse link
G Serpina1c serine (or cysteine) peptidase inhibitor, clade A, member 1C decreases expression EXP chromium nitrate results in decreased expression of SERPINA1C protein CTD PMID:23618972 NCBI chr12:103,894,926...103,904,950
Ensembl chr12:103,894,926...103,904,887
JBrowse link
G Serpinc1 serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1 decreases expression EXP chromium nitrate results in decreased expression of SERPINC1 protein CTD PMID:23618972 NCBI chr 1:160,978,583...161,002,543
Ensembl chr 1:160,978,585...161,005,863
JBrowse link
G Suclg2 succinate-Coenzyme A ligase, GDP-forming, beta subunit decreases expression EXP chromium nitrate results in decreased expression of SUCLG2 protein CTD PMID:22144121 NCBI chr 6:95,473,009...95,718,858
Ensembl chr 6:95,473,009...95,718,800
JBrowse link
G Tkfc triokinase, FMN cyclase increases expression EXP chromium nitrate results in increased expression of TKFC protein CTD PMID:22144121 NCBI chr19:10,592,197...10,605,482
Ensembl chr19:10,587,791...10,605,654
JBrowse link
G Uqcrc1 ubiquinol-cytochrome c reductase core protein 1 decreases expression EXP chromium nitrate results in decreased expression of UQCRC1 protein CTD PMID:22144121 NCBI chr 9:108,936,648...108,949,641
Ensembl chr 9:108,936,633...108,949,623
JBrowse link
G Vcp valosin containing protein decreases expression EXP chromium nitrate results in decreased expression of VCP protein CTD PMID:22144121 NCBI chr 4:42,979,964...43,000,507
Ensembl chr 4:42,979,963...43,000,507
JBrowse link
copper(II) nitrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl-hydrocarbon receptor multiple interactions ISO [copper(II) nitrate binds to 1,10-phenanthroline binds to Quinolones] which results in increased activity of AHR protein; [copper(II) nitrate binds to 5-methyl-1,10-phenanthroline binds to Quinolones] which results in increased activity of AHR protein; resveratrol inhibits the reaction [[copper(II) nitrate binds to 1,10-phenanthroline binds to Quinolones] which results in increased activity of AHR protein]; resveratrol inhibits the reaction [[copper(II) nitrate binds to 5-methyl-1,10-phenanthroline binds to Quinolones] which results in increased activity of AHR protein] CTD PMID:27180721 NCBI chr12:35,497,979...35,534,989
Ensembl chr12:35,497,974...35,535,038
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO [copper(II) nitrate binds to 1,10-phenanthroline binds to Quinolones] which results in increased expression of CYP1A1 mRNA; [copper(II) nitrate binds to 5-methyl-1,10-phenanthroline binds to Quinolones] which results in increased expression of CYP1A1 mRNA; [copper(II) nitrate binds to bathophenanthroline binds to Quinolones] which results in increased expression of CYP1A1 mRNA CTD PMID:27180721 NCBI chr 9:57,687,928...57,703,824
Ensembl chr 9:57,687,928...57,703,824
JBrowse link
G Il2 interleukin 2 decreases secretion ISO copper(II) nitrate results in decreased secretion of IL2 protein CTD PMID:27714827 NCBI chr 3:37,120,713...37,125,954
Ensembl chr 3:37,120,523...37,125,959
JBrowse link
lead nitrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aco1 aconitase 1 decreases expression
multiple interactions
ISO lead nitrate results in decreased expression of ACO1 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [lead nitrate results in decreased expression of ACO1 protein]
CTD PMID:22502979 NCBI chr 4:40,143,265...40,199,009
Ensembl chr 4:40,143,081...40,198,338
JBrowse link
G Acta1 actin, alpha 1, skeletal muscle increases expression EXP lead nitrate results in increased expression of ACTA1 protein CTD PMID:20435106 NCBI chr 8:123,891,758...123,894,775
Ensembl chr 8:123,891,769...123,894,751
JBrowse link
G Akap3 A kinase (PRKA) anchor protein 3 decreases expression ISO lead nitrate results in decreased expression of AKAP3 mRNA CTD PMID:21628963 NCBI chr 6:126,853,098...126,874,308
Ensembl chr 6:126,853,098...126,874,308
JBrowse link
G Alad aminolevulinate, delta-, dehydratase decreases activity
multiple interactions
ISO lead nitrate results in decreased activity of ALAD protein
lead nitrate inhibits the reaction [Dithiothreitol results in increased activity of ALAD protein]; lead nitrate inhibits the reaction [zinc chloride promotes the reaction [Dithiothreitol results in increased activity of ALAD protein]]
CTD PMID:2061546 NCBI chr 4:62,505,984...62,520,063
Ensembl chr 4:62,509,169...62,519,918
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 decreases expression
multiple interactions
EXP lead nitrate results in decreased expression of APAF1 protein
mangiferin inhibits the reaction [lead nitrate results in decreased expression of APAF1 protein]
CTD PMID:23451106 NCBI chr10:90,989,311...91,082,743
Ensembl chr10:90,989,311...91,082,770
JBrowse link
G Arhgdib Rho, GDP dissociation inhibitor (GDI) beta increases expression EXP lead nitrate results in increased expression of ARHGDIB protein CTD PMID:20435106 NCBI chr 6:136,923,655...136,941,899
Ensembl chr 6:136,923,655...136,941,899
JBrowse link
G Arrdc5 arrestin domain containing 5 decreases expression ISO lead nitrate results in decreased expression of ARRDC5 mRNA CTD PMID:21628963 NCBI chr17:56,294,111...56,300,286
Ensembl chr17:56,294,111...56,300,286
JBrowse link
G Azin2 antizyme inhibitor 2 decreases expression ISO lead nitrate results in decreased expression of AZIN2 mRNA CTD PMID:21628963 NCBI chr 4:128,930,233...128,962,456
Ensembl chr 4:128,930,233...128,962,442
JBrowse link
G Bax BCL2-associated X protein multiple interactions
increases expression
EXP
ISO
mangiferin inhibits the reaction [lead nitrate results in increased expression of BAX protein]
[lead nitrate results in increased abundance of Lead] which results in increased expression of BAX mRNA; titanium dioxide inhibits the reaction [[lead nitrate results in increased abundance of Lead] which results in decreased expression of BAX mRNA]; titanium dioxide inhibits the reaction [[lead nitrate results in increased abundance of Lead] which results in increased expression of BAX mRNA]
CTD PMID:23451106, PMID:30738203 NCBI chr 7:45,461,695...45,466,903
Ensembl chr 7:45,461,697...45,466,898
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 decreases expression
multiple interactions
EXP
ISO
lead nitrate results in decreased expression of BCL2 protein
[lead nitrate results in increased abundance of Lead] which results in decreased expression of BCL2 mRNA
mangiferin inhibits the reaction [lead nitrate results in decreased expression of BCL2 protein]
CTD PMID:23451106, PMID:30738203 NCBI chr 1:106,538,176...106,714,290
Ensembl chr 1:106,538,178...106,714,274
JBrowse link
G Casp3 caspase 3 increases expression
multiple interactions
increases activity
EXP
ISO
lead nitrate results in increased expression of CASP3 protein
[lead nitrate results in increased abundance of Lead] which results in increased activity of CASP3 protein; [lead nitrate results in increased abundance of Lead] which results in increased expression of CASP3 mRNA; titanium dioxide inhibits the reaction [[lead nitrate results in increased abundance of Lead] which results in increased activity of CASP3 protein]; titanium dioxide inhibits the reaction [[lead nitrate results in increased abundance of Lead] which results in increased expression of CASP3 mRNA]
puerarin inhibits the reaction [lead nitrate results in increased activity of CASP3 protein]
mangiferin inhibits the reaction [lead nitrate results in increased expression of CASP3 protein]
CTD PMID:23451106, PMID:24505050, PMID:30738203 NCBI chr 8:46,617,291...46,639,698
Ensembl chr 8:46,617,291...46,639,689
JBrowse link
G Casp7 caspase 7 multiple interactions
decreases expression
EXP lead nitrate affects the reaction [CASP7 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [CASP7 affects the expression of MT2 mRNA]
lead nitrate results in decreased expression of CASP7 mRNA
CTD PMID:11891201 NCBI chr19:56,396,833...56,442,348
Ensembl chr19:56,397,129...56,442,344
JBrowse link
G Casp9 caspase 9 multiple interactions
increases expression
EXP
ISO
mangiferin inhibits the reaction [lead nitrate results in increased expression of CASP9 protein]
[lead nitrate results in increased abundance of Lead] which results in increased activity of CASP9 protein; [lead nitrate results in increased abundance of Lead] which results in increased expression of CASP9 mRNA; titanium dioxide inhibits the reaction [[lead nitrate results in increased abundance of Lead] which results in increased activity of CASP9 protein]; titanium dioxide inhibits the reaction [[lead nitrate results in increased abundance of Lead] which results in increased expression of CASP9 mRNA]
CTD PMID:23451106, PMID:30738203 NCBI chr 4:141,793,612...141,815,978
Ensembl chr 4:141,793,612...141,815,976
JBrowse link
G Cat catalase decreases activity
multiple interactions
EXP
ISO
lead nitrate results in decreased activity of CAT protein
[lead nitrate results in increased abundance of Lead] which results in decreased activity of CAT protein; titanium dioxide inhibits the reaction [[lead nitrate results in increased abundance of Lead] which results in decreased activity of CAT protein]
Ashwagandha inhibits the reaction [lead nitrate results in decreased activity of CAT protein]; puerarin inhibits the reaction [lead nitrate results in decreased activity of CAT protein]
mangiferin inhibits the reaction [lead nitrate results in decreased activity of CAT protein]
CTD PMID:23315276, PMID:23451106, PMID:24987671, PMID:30738203 NCBI chr 2:103,453,904...103,485,153
Ensembl chr 2:103,453,849...103,485,160
JBrowse link
G Ccng1 cyclin G1 multiple interactions EXP lead nitrate affects the reaction [CCNG1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [CCNG1 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr11:40,748,552...40,755,309
Ensembl chr11:40,748,552...40,755,311
JBrowse link
G Cd86 CD86 antigen increases expression EXP lead nitrate results in increased expression of CD86 protein CTD PMID:23376802 NCBI chr16:36,568,956...36,666,158
Ensembl chr16:36,603,869...36,666,081
JBrowse link
G Cdyl chromodomain protein, Y chromosome-like decreases expression ISO lead nitrate results in decreased expression of CDYL mRNA CTD PMID:21628963 NCBI chr13:35,659,818...35,874,064
Ensembl chr13:35,659,833...35,874,063
JBrowse link
G Chuk conserved helix-loop-helix ubiquitous kinase increases phosphorylation
multiple interactions
EXP lead nitrate results in increased phosphorylation of CHUK protein
mangiferin inhibits the reaction [lead nitrate results in increased phosphorylation of CHUK protein]
CTD PMID:23451106 NCBI chr19:44,073,334...44,107,505
Ensembl chr19:44,073,335...44,107,480
JBrowse link
G Cox8c cytochrome c oxidase subunit 8C decreases expression ISO lead nitrate results in decreased expression of COX8C mRNA CTD PMID:21628963 NCBI chr12:102,899,306...102,900,534
Ensembl chr12:102,899,316...102,900,526
JBrowse link
G Crisp2 cysteine-rich secretory protein 2 decreases expression ISO lead nitrate results in decreased expression of CRISP2 mRNA CTD PMID:21628963 NCBI chr17:40,764,734...40,794,146
Ensembl chr17:40,764,020...40,807,003
JBrowse link
G Cryaa crystallin, alpha A affects metabolic processing ISO lead nitrate affects the metabolism of CRYAA protein CTD PMID:21139692 NCBI chr17:31,677,931...31,681,730
Ensembl chr17:31,677,807...31,681,733
JBrowse link
G Cryab crystallin, alpha B affects metabolic processing ISO lead nitrate affects the metabolism of CRYAB protein CTD PMID:21139692 NCBI chr 9:50,745,951...50,756,636
Ensembl chr 9:50,751,325...50,756,636
JBrowse link
G Cst8 cystatin 8 (cystatin-related epididymal spermatogenic) decreases expression ISO lead nitrate results in decreased expression of CST8 mRNA CTD PMID:21628963 NCBI chr 2:148,798,839...148,805,596
Ensembl chr 2:148,798,785...148,805,595
JBrowse link
G Ctnna1 catenin (cadherin associated protein), alpha 1 multiple interactions EXP lead nitrate affects the reaction [CTNNA1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [CTNNA1 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr18:35,118,902...35,254,776
Ensembl chr18:35,118,859...35,254,779
JBrowse link
G Ctnnb1 catenin (cadherin associated protein), beta 1 multiple interactions EXP [lead nitrate results in increased abundance of Lead] which results in decreased expression of and affects the localization of CTNNB1 protein; [lead nitrate results in increased abundance of Lead] which results in decreased expression of CTNNB1 mRNA; icaritin inhibits the reaction [[lead nitrate results in increased abundance of Lead] which results in decreased expression of and affects the localization of CTNNB1 protein]; icaritin inhibits the reaction [[lead nitrate results in increased abundance of Lead] which results in decreased expression of CTNNB1 mRNA] CTD PMID:30731080 NCBI chr 9:120,933,400...120,960,507
Ensembl chr 9:120,929,216...120,960,507
JBrowse link
G Cux2 cut-like homeobox 2 multiple interactions EXP lead nitrate affects the reaction [CUX2 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [CUX2 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr 5:121,857,962...122,050,415
Ensembl chr 5:121,856,366...122,050,102
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases expression
ISO lead nitrate inhibits the reaction [1,2,5,6-dibenzanthracene results in increased activity of CYP1A1 protein]; lead nitrate inhibits the reaction [benz(a)anthracene results in increased activity of CYP1A1 protein]; lead nitrate inhibits the reaction [Benzo(a)pyrene results in increased activity of CYP1A1 protein]; lead nitrate inhibits the reaction [benzo(b)fluoranthene results in increased activity of CYP1A1 protein]; lead nitrate inhibits the reaction [benzo(k)fluoranthene results in increased activity of CYP1A1 protein]; lead nitrate inhibits the reaction [benzo(k)fluoranthene results in increased expression of CYP1A1 protein]; lead nitrate inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of CYP1A1 protein]; lead nitrate promotes the reaction [benzo(k)fluoranthene results in increased expression of CYP1A1 protein]
lead nitrate inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CYP1A1 protein]; lead nitrate inhibits the reaction [2-amino-3-methyl-9H-pyrido(2,3-b)indole results in increased expression of CYP1A1 mRNA]; lead nitrate inhibits the reaction [2-amino-3-methyl-9H-pyrido(2,3-b)indole results in increased expression of CYP1A1 protein]; lead nitrate inhibits the reaction [2-methoxy-4-aminoazobenzene results in increased expression of CYP1A1 protein]; lead nitrate inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 protein]; lead nitrate inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 protein]; lead nitrate inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 protein]; Resveratrol inhibits the reaction [lead nitrate results in increased expression of CYP1A1 mRNA]
lead nitrate results in increased expression of CYP1A1 mRNA; lead nitrate results in increased expression of CYP1A1 protein
CTD PMID:8902619, PMID:11162773, PMID:11408366, PMID:17889500, PMID:23391631 NCBI chr 9:57,687,928...57,703,824
Ensembl chr 9:57,687,928...57,703,824
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases activity
multiple interactions
ISO lead nitrate results in decreased activity of CYP1A2 protein
lead nitrate inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CYP1A2 mRNA]; lead nitrate inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CYP1A2 protein]; lead nitrate inhibits the reaction [2-amino-3-methyl-9H-pyrido(2,3-b)indole results in increased expression of CYP1A2 mRNA]; lead nitrate inhibits the reaction [2-amino-3-methyl-9H-pyrido(2,3-b)indole results in increased expression of CYP1A2 protein]; lead nitrate inhibits the reaction [2-methoxy-4-aminoazobenzene results in increased expression of CYP1A2 mRNA]; lead nitrate inhibits the reaction [2-methoxy-4-aminoazobenzene results in increased expression of CYP1A2 protein]; lead nitrate inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 protein]; lead nitrate inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A2 protein]; lead nitrate inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A2 protein]; lead nitrate results in decreased expression of and results in decreased activity of CYP1A2 protein
CTD PMID:8902619, PMID:11162773 NCBI chr 9:57,676,937...57,683,655
Ensembl chr 9:57,676,937...57,683,703
JBrowse link
G Cyp2c52-ps cytochrome P450, family 2, subfamily c, polypeptide 52, pseudogene increases expression ISO lead nitrate results in increased expression of CYP2C11 mRNA CTD PMID:23391631 NCBI chr19:38,976,662...39,003,627
Ensembl chr19:38,976,647...39,003,289
JBrowse link
G Cyp4a12b cytochrome P450, family 4, subfamily a, polypeptide 12B increases expression ISO lead nitrate results in increased expression of CYP4A1 mRNA CTD PMID:23391631 NCBI chr 4:115,411,624...115,439,034
Ensembl chr 4:115,411,624...115,439,034
JBrowse link
G Cyp51 cytochrome P450, family 51 increases expression
multiple interactions
EXP
ISO
lead nitrate results in increased expression of CYP51 mRNA
[IL1A gene mutant form co-treated with IL1B gene mutant form] inhibits the reaction [lead nitrate results in increased expression of CYP51 mRNA]
CTD PMID:15475176, PMID:22293356 NCBI chr 5:4,080,674...4,104,697
Ensembl chr 5:4,081,145...4,104,746
JBrowse link
G Cyp7a1 cytochrome P450, family 7, subfamily a, polypeptide 1 decreases expression
multiple interactions
EXP
ISO
lead nitrate results in decreased expression of CYP7A1 mRNA
[IL1A gene mutant form co-treated with IL1B gene mutant form] inhibits the reaction [lead nitrate results in decreased expression of CYP7A1 mRNA]
CTD PMID:15475176, PMID:16049268, PMID:22293356 NCBI chr 4:6,265,612...6,275,632
Ensembl chr 4:6,265,612...6,275,633
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO lead nitrate results in increased expression of DDIT3 mRNA CTD PMID:14971657 NCBI chr10:127,290,793...127,296,291
Ensembl chr10:127,290,774...127,296,288
Ensembl chr10:127,290,774...127,296,288
JBrowse link
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 multiple interactions EXP [lead nitrate results in increased abundance of Lead] which results in increased expression of DKK1 mRNA; [lead nitrate results in increased abundance of Lead] which results in increased expression of DKK1 protein; icaritin inhibits the reaction [[lead nitrate results in increased abundance of Lead] which results in increased expression of DKK1 mRNA]; icaritin inhibits the reaction [[lead nitrate results in increased abundance of Lead] which results in increased expression of DKK1 protein] CTD PMID:30731080 NCBI chr19:30,545,876...30,549,496
Ensembl chr19:30,545,863...30,549,665
JBrowse link
G Dnase1 deoxyribonuclease I multiple interactions EXP lead nitrate affects the reaction [DNASE1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [DNASE1 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr16:4,036,958...4,040,024
Ensembl chr16:4,036,942...4,040,024
JBrowse link
G Dnmt3a DNA methyltransferase 3A multiple interactions
decreases expression
ISO 4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline inhibits the reaction [lead nitrate results in decreased expression of DNMT3A mRNA]; E2F1 protein inhibits the reaction [lead nitrate results in decreased expression of DNMT3A mRNA]; RTKI cpd inhibits the reaction [lead nitrate results in decreased expression of DNMT3A mRNA]
lead nitrate results in decreased expression of DNMT3A mRNA; lead nitrate results in decreased expression of DNMT3A protein
CTD PMID:24639330 NCBI chr12:3,801,559...3,914,443
Ensembl chr12:3,806,007...3,914,443
JBrowse link
G E2f1 E2F transcription factor 1 multiple interactions ISO E2F1 protein inhibits the reaction [lead nitrate results in decreased expression of DNMT3A mRNA]; E2F1 protein inhibits the reaction [lead nitrate results in increased expression of PTGS2 mRNA]; lead nitrate inhibits the reaction [E2F1 protein results in decreased expression of PTGS2 mRNA] CTD PMID:24639330 NCBI chr 2:154,559,400...154,569,892
Ensembl chr 2:154,559,407...154,569,892
JBrowse link
G Egfl8 EGF-like domain 8 increases expression ISO lead nitrate results in increased expression of EGFL8 protein CTD PMID:19332663 NCBI chr17:34,613,349...34,616,562
Ensembl chr17:34,613,349...34,615,971
JBrowse link
G Egfr epidermal growth factor receptor multiple interactions
increases phosphorylation
ISO EGFR mutant form affects the reaction [[lead nitrate results in increased expression of PLA2G4A mRNA] which results in increased secretion of Dinoprostone]; EGFR mutant form affects the reaction [lead nitrate results in increased expression of PLA2G4A mRNA]; EGFR mutant form affects the reaction [lead nitrate results in increased secretion of Dinoprostone]; EGFR promotes the reaction [lead nitrate results in increased expression of PLA2G4A mRNA]; RTKI cpd inhibits the reaction [lead nitrate results in increased phosphorylation of EGFR protein] CTD PMID:20850495 NCBI chr11:16,752,203...16,913,907
Ensembl chr11:16,752,203...16,918,158
JBrowse link
G Eif2ak1 eukaryotic translation initiation factor 2 alpha kinase 1 increases response to substance
multiple interactions
EXP EIF2AK1 gene mutant form results in increased susceptibility to lead nitrate
[lead nitrate co-treated with EIF2AK1 gene mutant form] results in increased abundance of Bilirubin; [lead nitrate co-treated with EIF2AK1 gene mutant form] results in increased abundance of Malondialdehyde; [lead nitrate co-treated with EIF2AK1 gene mutant form] results in increased expression of HAMP mRNA
CTD PMID:25411909 NCBI chr 5:143,817,792...143,902,717
Ensembl chr 5:143,817,788...143,904,251
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 increases phosphorylation
multiple interactions
ISO lead nitrate results in increased phosphorylation of EIF4EBP1 protein
puerarin inhibits the reaction [lead nitrate results in increased phosphorylation of EIF4EBP1 protein]
CTD PMID:27762461 NCBI chr 8:27,260,327...27,275,656
Ensembl chr 8:27,260,329...27,276,674
JBrowse link
G Ercc1 excision repair cross-complementing rodent repair deficiency, complementation group 1 multiple interactions EXP lead nitrate affects the reaction [ERCC1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [ERCC1 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr 7:19,344,067...19,356,524
Ensembl chr 7:19,344,778...19,356,524
JBrowse link
G Ercc3 excision repair cross-complementing rodent repair deficiency, complementation group 3 multiple interactions EXP lead nitrate affects the reaction [ERCC3 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [ERCC3 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr18:32,240,304...32,270,151
Ensembl chr18:32,240,300...32,270,151
JBrowse link
G Ezr ezrin multiple interactions EXP lead nitrate affects the reaction [EZR affects the expression of MT1 mRNA]; lead nitrate affects the reaction [EZR affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr17:6,738,131...6,782,780
Ensembl chr17:6,738,041...6,782,784
JBrowse link
G Fabp9 fatty acid binding protein 9, testis decreases expression ISO lead nitrate results in decreased expression of FABP9 mRNA CTD PMID:21628963 NCBI chr 3:10,193,623...10,197,283
Ensembl chr 3:10,193,621...10,197,283
JBrowse link
G Fam71f1 family with sequence similarity 71, member F1 decreases expression ISO lead nitrate results in decreased expression of FAM71F1 mRNA CTD PMID:21628963 NCBI chr 6:29,313,469...29,336,022
Ensembl chr 6:29,319,140...29,336,019
JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 increases expression ISO lead nitrate results in increased expression of FDFT1 mRNA CTD PMID:15475176 NCBI chr14:63,145,150...63,181,687
Ensembl chr14:63,145,150...63,179,578
JBrowse link
G Fdps farnesyl diphosphate synthetase increases expression ISO lead nitrate results in increased expression of FDPS mRNA CTD PMID:15475176 NCBI chr 3:89,093,588...89,101,967
Ensembl chr 3:89,093,588...89,101,959
JBrowse link
G Fhl1 four and a half LIM domains 1 decreases expression ISO lead nitrate results in decreased expression of FHL1 mRNA CTD PMID:21628963 NCBI chr  X:56,731,209...56,793,346
Ensembl chr  X:56,731,787...56,793,346
JBrowse link
G Fos FBJ osteosarcoma oncogene increases expression ISO lead nitrate results in increased expression of FOS mRNA CTD PMID:14971657 NCBI chr12:85,473,890...85,477,274
Ensembl chr12:85,473,890...85,477,273
JBrowse link
G Foxa2 forkhead box A2 multiple interactions EXP lead nitrate affects the reaction [FOXA2 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [FOXA2 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr 2:148,042,877...148,046,969
Ensembl chr 2:148,042,877...148,046,969
JBrowse link
G Ftl1 ferritin light polypeptide 1 increases expression ISO lead nitrate results in increased expression of FTL protein CTD PMID:19332663 NCBI chr 7:45,457,944...45,459,886
Ensembl chr 7:45,457,944...45,459,884
JBrowse link
G G6pdx glucose-6-phosphate dehydrogenase X-linked decreases activity ISO lead nitrate results in decreased activity of G6PD protein CTD PMID:28557068 NCBI chr  X:74,409,483...74,428,880
Ensembl chr  X:74,409,483...74,429,194
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible 45 alpha increases expression ISO lead nitrate results in increased expression of GADD45A mRNA CTD PMID:14971657 NCBI chr 6:67,035,096...67,037,407
Ensembl chr 6:67,035,096...67,037,457
JBrowse link
G Gfap glial fibrillary acidic protein multiple interactions
increases expression
ISO Ashwagandha inhibits the reaction [lead nitrate results in increased expression of GFAP mRNA]; Ashwagandha inhibits the reaction [lead nitrate results in increased expression of GFAP protein]
lead nitrate results in increased expression of GFAP mRNA; lead nitrate results in increased expression of GFAP protein
CTD PMID:24987671 NCBI chr11:102,887,336...102,897,200
Ensembl chr11:102,887,336...102,900,912
JBrowse link
G Ggnbp1 gametogenetin binding protein 1 decreases expression ISO lead nitrate results in decreased expression of GGNBP1 mRNA CTD PMID:21628963 NCBI chr17:27,018,035...27,036,378
Ensembl chr17:27,017,987...27,037,624
JBrowse link
G Gh growth hormone multiple interactions
decreases secretion
ISO lead nitrate inhibits the reaction [GHRH protein results in increased expression of GH1 protein]
lead nitrate results in decreased secretion of GH1 protein
CTD PMID:12022635 NCBI chr11:106,300,261...106,303,703
Ensembl chr11:106,300,271...106,301,865
JBrowse link
G Ghrh growth hormone releasing hormone multiple interactions ISO lead nitrate inhibits the reaction [GHRH protein results in increased expression of GH1 protein] CTD PMID:12022635 NCBI chr 2:157,329,496...157,348,725
Ensembl chr 2:157,329,497...157,347,506
JBrowse link
G Gja5 gap junction protein, alpha 5 multiple interactions
increases expression
EXP lead nitrate affects the reaction [GJA5 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [GJA5 affects the expression of MT2 mRNA]
lead nitrate results in increased expression of GJA5 mRNA
CTD PMID:11891201 NCBI chr 3:97,032,402...97,053,634
Ensembl chr 3:96,904,693...97,077,416
JBrowse link
G Gjb2 gap junction protein, beta 2 multiple interactions EXP lead nitrate affects the reaction [GJB2 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [GJB2 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr14:57,098,602...57,104,702
Ensembl chr14:57,098,600...57,104,702
JBrowse link
G Gm128 predicted gene 128 decreases expression ISO lead nitrate results in decreased expression of RGD1359334 mRNA CTD PMID:21628963 NCBI chr 3:95,236,919...95,241,635
Ensembl chr 3:95,236,920...95,241,598
JBrowse link
G Grin2a glutamate receptor, ionotropic, NMDA2A (epsilon 1) multiple interactions EXP lead nitrate affects the reaction [GRIN2A affects the expression of MT1 mRNA]; lead nitrate affects the reaction [GRIN2A affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr16:9,567,901...9,996,083
Ensembl chr16:9,567,898...9,995,560
JBrowse link
G Grin2c glutamate receptor, ionotropic, NMDA2C (epsilon 3) increases expression ISO lead nitrate results in increased expression of GRIN2C mRNA CTD PMID:23358146 NCBI chr11:115,249,169...115,267,297
Ensembl chr11:115,249,169...115,267,243
JBrowse link
G Gsg1 germ cell associated 1 decreases expression ISO lead nitrate results in decreased expression of GSG1 mRNA CTD PMID:21628963 NCBI chr 6:135,237,329...135,254,336
Ensembl chr 6:135,237,326...135,254,351
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions EXP [lead nitrate results in increased abundance of Lead] which results in decreased phosphorylation of GSK3B protein; icaritin inhibits the reaction [[lead nitrate results in increased abundance of Lead] which results in decreased phosphorylation of GSK3B protein] CTD PMID:30731080 NCBI chr16:38,089,001...38,246,084
Ensembl chr16:38,089,001...38,246,084
JBrowse link
G Gsr glutathione reductase multiple interactions
decreases activity
EXP mangiferin inhibits the reaction [lead nitrate results in decreased activity of GSR protein] CTD PMID:23451106 NCBI chr 8:33,653,238...33,698,162
Ensembl chr 8:33,652,523...33,698,163
JBrowse link
G Gstt1 glutathione S-transferase, theta 1 multiple interactions EXP lead nitrate affects the reaction [GSTT1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [GSTT1 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr10:75,783,813...75,798,584
Ensembl chr10:75,783,813...75,798,584
JBrowse link
G Hamp hepcidin antimicrobial peptide multiple interactions EXP [lead nitrate co-treated with EIF2AK1 gene mutant form] results in increased expression of HAMP mRNA CTD PMID:25411909 NCBI chr 7:30,942,368...30,944,029
Ensembl chr 7:30,942,368...30,944,032
JBrowse link
G Hmgb4 high-mobility group box 4 decreases expression ISO lead nitrate results in decreased expression of HMGB4 mRNA CTD PMID:21628963 NCBI chr 4:128,260,212...128,260,895
Ensembl chr 4:128,260,212...128,260,957
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-Coenzyme A reductase increases expression
multiple interactions
EXP
ISO
lead nitrate results in increased expression of HMGCR mRNA
[IL1A gene mutant form co-treated with IL1B gene mutant form] inhibits the reaction [lead nitrate results in increased expression of HMGCR mRNA]
CTD PMID:15475176, PMID:16705668, PMID:22293356 NCBI chr13:96,648,962...96,670,936
Ensembl chr13:96,648,967...96,670,936
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO lead nitrate results in increased expression of HMOX1 mRNA CTD PMID:23391631 NCBI chr 8:75,093,618...75,100,593
Ensembl chr 8:75,093,621...75,100,589
JBrowse link
G Hnf4a hepatic nuclear factor 4, alpha decreases expression EXP lead nitrate results in decreased expression of HNF4A mRNA CTD PMID:16049268 NCBI chr 2:163,506,811...163,572,907
Ensembl chr 2:163,506,808...163,572,910
JBrowse link
G Hsp90ab1 heat shock protein 90 alpha (cytosolic), class B member 1 multiple interactions EXP lead nitrate affects the reaction [HSP90AB1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [HSP90AB1 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr17:45,567,778...45,573,261
Ensembl chr17:45,567,775...45,573,271
JBrowse link
G Hspa2 heat shock protein 2 multiple interactions
decreases expression
increases expression
ISO Ashwagandha inhibits the reaction [lead nitrate results in increased expression of HSPA2 mRNA]
lead nitrate results in decreased expression of HSPA2 mRNA
CTD PMID:21628963, PMID:24987671 NCBI chr12:76,403,812...76,406,938
Ensembl chr12:76,404,176...76,406,938
JBrowse link
G Hspa5 heat shock protein 5 increases expression EXP
ISO
lead nitrate results in increased expression of HSPA5 protein
lead nitrate results in increased expression of HSPA5 mRNA
CTD PMID:14971657, PMID:20435106 NCBI chr 2:34,772,090...34,776,529
Ensembl chr 2:34,771,970...34,777,547
JBrowse link
G Hspa9 heat shock protein 9 multiple interactions
increases expression
ISO Ashwagandha inhibits the reaction [lead nitrate results in increased expression of HSPA9 mRNA]; Ashwagandha inhibits the reaction [lead nitrate results in increased expression of HSPA9 protein]
lead nitrate results in increased expression of HSPA9 mRNA; lead nitrate results in increased expression of HSPA9 protein
CTD PMID:24987671 NCBI chr18:34,937,414...34,954,351
Ensembl chr18:34,937,414...34,954,357
JBrowse link
G Igf2 insulin-like growth factor 2 multiple interactions EXP lead nitrate affects the reaction [IGF2 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [IGF2 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr 7:142,650,768...142,666,816
Ensembl chr 7:142,650,766...142,666,816
JBrowse link
G Igfbp6 insulin-like growth factor binding protein 6 multiple interactions EXP lead nitrate affects the reaction [IGFBP6 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [IGFBP6 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr15:102,144,186...102,149,512
Ensembl chr15:102,144,362...102,149,511
JBrowse link
G Il1a interleukin 1 alpha multiple interactions
increases expression
EXP [IL1A gene mutant form co-treated with IL1B gene mutant form] inhibits the reaction [lead nitrate results in decreased expression of CYP7A1 mRNA]; [IL1A gene mutant form co-treated with IL1B gene mutant form] inhibits the reaction [lead nitrate results in increased expression of CYP51 mRNA]; [IL1A gene mutant form co-treated with IL1B gene mutant form] inhibits the reaction [lead nitrate results in increased expression of HMGCR mRNA]; [IL1A gene mutant form co-treated with IL1B gene mutant form] inhibits the reaction [lead nitrate results in increased expression of TNF mRNA]; [IL1A gene mutant form co-treated with IL1B gene mutant form] results in decreased susceptibility to lead nitrate
lead nitrate results in increased expression of IL1A mRNA
CTD PMID:22293356 NCBI chr 2:129,299,609...129,310,186
Ensembl chr 2:129,299,610...129,309,972
JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases expression
EXP
ISO
[IL1A gene mutant form co-treated with IL1B gene mutant form] inhibits the reaction [lead nitrate results in decreased expression of CYP7A1 mRNA]; [IL1A gene mutant form co-treated with IL1B gene mutant form] inhibits the reaction [lead nitrate results in increased expression of CYP51 mRNA]; [IL1A gene mutant form co-treated with IL1B gene mutant form] inhibits the reaction [lead nitrate results in increased expression of HMGCR mRNA]; [IL1A gene mutant form co-treated with IL1B gene mutant form] inhibits the reaction [lead nitrate results in increased expression of TNF mRNA]; [IL1A gene mutant form co-treated with IL1B gene mutant form] results in decreased susceptibility to lead nitrate
lead nitrate results in increased expression of IL1B mRNA
lead nitrate results in increased expression of IL1B mRNA; lead nitrate results in increased expression of IL1B protein
CTD PMID:15475176, PMID:16049268, PMID:22293356 NCBI chr 2:129,364,569...129,371,164
Ensembl chr 2:129,364,570...129,371,139
JBrowse link
G Il2 interleukin 2 decreases secretion ISO lead nitrate results in decreased secretion of IL2 protein CTD PMID:27714827 NCBI chr 3:37,120,713...37,125,954
Ensembl chr 3:37,120,523...37,125,959
JBrowse link
G Il6ra interleukin 6 receptor, alpha multiple interactions EXP lead nitrate affects the reaction [IL6RA affects the expression of MT1 mRNA]; lead nitrate affects the reaction [IL6RA affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr 3:89,869,324...89,913,196
Ensembl chr 3:89,864,059...89,913,196
JBrowse link
G Iqcf1 IQ motif containing F1 decreases expression ISO lead nitrate results in decreased expression of IQCF1 mRNA CTD PMID:21628963 NCBI chr 9:106,499,967...106,502,250
Ensembl chr 9:106,499,967...106,502,254
JBrowse link
G Iqcf5 IQ motif containing F5 decreases expression ISO lead nitrate results in decreased expression of IQCF5 mRNA CTD PMID:21628963 NCBI chr 9:106,514,573...106,516,003
Ensembl chr 9:106,514,573...106,516,010
JBrowse link
G Itga6 integrin alpha 6 multiple interactions EXP lead nitrate affects the reaction [ITGA6 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [ITGA6 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr 2:71,786,886...71,858,427
Ensembl chr 2:71,745,616...71,858,416
JBrowse link
G Itgam integrin alpha M multiple interactions EXP lead nitrate affects the reaction [ITGAM affects the expression of MT1 mRNA]; lead nitrate affects the reaction [ITGAM affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr 7:128,062,640...128,118,491
Ensembl chr 7:128,062,640...128,118,491
JBrowse link
G Krt14 keratin 14 increases expression EXP lead nitrate results in increased expression of KRT14 protein CTD PMID:20435106 NCBI chr11:100,203,162...100,207,510
Ensembl chr11:100,203,162...100,207,548
JBrowse link
G Lamp1 lysosomal-associated membrane protein 1 increases expression EXP lead nitrate results in increased expression of LAMP1 protein CTD PMID:23376802 NCBI chr 8:13,159,161...13,175,338
Ensembl chr 8:13,159,161...13,175,338
JBrowse link
G Lamp2 lysosomal-associated membrane protein 2 increases expression EXP lead nitrate results in increased expression of LAMP2 protein CTD PMID:23376802 NCBI chr  X:38,399,647...38,456,460
Ensembl chr  X:38,401,357...38,456,454
JBrowse link
G Ldhc lactate dehydrogenase C decreases expression ISO lead nitrate results in decreased expression of LDHC mRNA CTD PMID:21628963 NCBI chr 7:46,861,263...46,878,147
Ensembl chr 7:46,861,203...46,878,142
JBrowse link
G Lrrc46 leucine rich repeat containing 46 decreases expression ISO lead nitrate results in decreased expression of LRRC46 mRNA CTD PMID:21628963 NCBI chr11:97,034,602...97,041,369
Ensembl chr11:97,034,602...97,041,407
JBrowse link
G Lta lymphotoxin A multiple interactions EXP lead nitrate affects the reaction [LTA affects the expression of MT1 mRNA]; lead nitrate affects the reaction [LTA affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr17:35,203,165...35,205,578
Ensembl chr17:35,203,165...35,205,351
JBrowse link
G Lypd4 Ly6/Plaur domain containing 4 decreases expression ISO lead nitrate results in decreased expression of LYPD4 mRNA CTD PMID:21628963 NCBI chr 7:24,864,617...24,869,924
Ensembl chr 7:24,864,620...24,869,941
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 multiple interactions
increases phosphorylation
ISO
EXP
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [lead nitrate results in increased phosphorylation of MAPK1 protein]; 4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline inhibits the reaction [lead nitrate results in increased phosphorylation of MAPK1 protein]; RTKI cpd inhibits the reaction [lead nitrate results in increased phosphorylation of MAPK1 protein]
mangiferin inhibits the reaction [lead nitrate results in increased phosphorylation of MAPK1 protein]
CTD PMID:20850495, PMID:22502979, PMID:23451106 NCBI chr16:16,983,382...17,047,453
Ensembl chr16:16,983,382...17,047,453
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 multiple interactions
increases phosphorylation
ISO
EXP
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [lead nitrate results in increased phosphorylation of MAPK3 protein]; 4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline inhibits the reaction [lead nitrate results in increased phosphorylation of MAPK3 protein]; RTKI cpd inhibits the reaction [lead nitrate results in increased phosphorylation of MAPK3 protein]
mangiferin inhibits the reaction [lead nitrate results in increased phosphorylation of MAPK3 protein]
CTD PMID:20850495, PMID:22502979, PMID:23451106 NCBI chr 7:126,759,626...126,765,816
Ensembl chr 7:126,759,601...126,765,819
JBrowse link
G Marchf11 membrane associated ring-CH-type finger 11 decreases expression ISO lead nitrate results in decreased expression of MARCHF11 mRNA CTD PMID:21628963 NCBI chr15:26,309,048...26,409,586
Ensembl chr15:26,309,048...26,409,576
JBrowse link
G Mcl1 myeloid cell leukemia sequence 1 multiple interactions EXP lead nitrate affects the reaction [MCL1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [MCL1 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr 3:95,656,944...95,663,179
Ensembl chr 3:95,658,788...95,663,176
JBrowse link
G Met met proto-oncogene multiple interactions EXP lead nitrate affects the reaction [MET affects the expression of MT1 mRNA]; lead nitrate affects the reaction [MET affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr 6:17,463,349...17,573,980
Ensembl chr 6:17,463,800...17,573,980
JBrowse link
G Mgst1 microsomal glutathione S-transferase 1 multiple interactions EXP lead nitrate affects the reaction [MGST1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [MGST1 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr 6:138,140,527...138,156,755
Ensembl chr 6:138,140,316...138,156,755
JBrowse link
G Mroh2b maestro heat-like repeat family member 2B decreases expression ISO lead nitrate results in decreased expression of MROH2B mRNA CTD PMID:21628963 NCBI chr15:4,898,215...4,962,207
Ensembl chr15:4,898,737...4,962,205
JBrowse link
G mt-Co1 cytochrome c oxidase I, mitochondrial multiple interactions
decreases expression
ISO puerarin inhibits the reaction [lead nitrate results in decreased expression of COX1 mRNA] CTD PMID:23315276 NCBI chr MT:5,328...6,872
Ensembl chr MT:5,328...6,872
JBrowse link
G mt-Co2 cytochrome c oxidase II, mitochondrial multiple interactions
decreases expression
ISO puerarin inhibits the reaction [lead nitrate results in decreased expression of COX2 mRNA] CTD PMID:23315276 NCBI chr MT:7,013...7,696
Ensembl chr MT:7,013...7,696
JBrowse link
G mt-Co3 cytochrome c oxidase III, mitochondrial multiple interactions
decreases expression
ISO puerarin inhibits the reaction [lead nitrate results in decreased expression of COX3 mRNA] CTD PMID:23315276 NCBI chr MT:8,607...9,390
Ensembl chr MT:8,607...9,390
JBrowse link
G Mt1 metallothionein 1 affects localization
decreases response to substance
increases expression
multiple interactions
EXP lead nitrate affects the localization of MT1 protein
MT1 results in decreased susceptibility to lead nitrate
lead nitrate results in increased expression of MT1 mRNA
lead nitrate affects the reaction [CASP7 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [CCNG1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [CTNNA1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [CUX2 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [DNASE1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [ERCC1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [ERCC3 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [EZR affects the expression of MT1 mRNA]; lead nitrate affects the reaction [FOXA2 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [GJA5 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [GJB2 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [GRIN2A affects the expression of MT1 mRNA]; lead nitrate affects the reaction [GSTT1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [HSP90AB1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [IGF2 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [IGFBP6 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [IL6RA affects the expression of MT1 mRNA]; lead nitrate affects the reaction [ITGA6 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [ITGAM affects the expression of MT1 mRNA]; lead nitrate affects the reaction [LTA affects the expression of MT1 mRNA]; lead nitrate affects the reaction [MCL1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [MET affects the expression of MT1 mRNA]; lead nitrate affects the reaction [MGST1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [MYC affects the expression of MT1 mRNA]; lead nitrate affects the reaction [NFKBIB affects the expression of MT1 mRNA]; lead nitrate affects the reaction [NUMB affects the expression of MT1 mRNA]; lead nitrate affects the reaction [PIAS2 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [POLD1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [POU3F3 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [RAD23 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [RBL2 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [RUNX1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [SERPINA1B affects the expression of MT1 mRNA]; lead nitrate affects the reaction [SOCS1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [SP3 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [SQSTM1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [SUMO1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [TBX2 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [TNFRSF1A affects the expression of MT1 mRNA]; lead nitrate affects the reaction [TNFRSF1B affects the expression of MT1 mRNA]; lead nitrate affects the reaction [TRIM27 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [TSG101 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [TTF1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [WNT4 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [ZFHX3 affects the expression of MT1 mRNA]; MT1 protein promotes the reaction [lead nitrate results in increased expression of SNCA mRNA]
CTD PMID:11891201, PMID:19542206 NCBI chr 8:94,178,883...94,180,327
Ensembl chr 8:94,179,082...94,180,327
JBrowse link
G Mt2 metallothionein 2 multiple interactions
decreases response to substance
EXP lead nitrate affects the reaction [CASP7 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [CCNG1 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [CTNNA1 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [CUX2 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [DNASE1 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [ERCC1 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [ERCC3 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [EZR affects the expression of MT2 mRNA]; lead nitrate affects the reaction [FOXA2 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [GJA5 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [GJB2 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [GRIN2A affects the expression of MT2 mRNA]; lead nitrate affects the reaction [GSTT1 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [HSP90AB1 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [IGF2 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [IGFBP6 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [IL6RA affects the expression of MT2 mRNA]; lead nitrate affects the reaction [ITGA6 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [ITGAM affects the expression of MT2 mRNA]; lead nitrate affects the reaction [LTA affects the expression of MT2 mRNA]; lead nitrate affects the reaction [MCL1 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [MET affects the expression of MT2 mRNA]; lead nitrate affects the reaction [MGST1 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [MYC affects the expression of MT2 mRNA]; lead nitrate affects the reaction [NFKBIB affects the expression of MT2 mRNA]; lead nitrate affects the reaction [NUMB affects the expression of MT2 mRNA]; lead nitrate affects the reaction [PIAS2 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [POLD1 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [POU3F3 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [RAD23 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [RBL2 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [RUNX1 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [SERPINA1B affects the expression of MT2 mRNA]; lead nitrate affects the reaction [SOCS1 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [SP3 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [SQSTM1 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [SUMO1 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [TBX2 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [TNFRSF1A affects the expression of MT2 mRNA]; lead nitrate affects the reaction [TNFRSF1B affects the expression of MT2 mRNA]; lead nitrate affects the reaction [TRIM27 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [TSG101 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [TTF1 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [WNT4 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [ZFHX3 affects the expression of MT2 mRNA]
MT2 results in decreased susceptibility to lead nitrate
CTD PMID:11891201 NCBI chr 8:94,172,618...94,173,567
Ensembl chr 8:94,172,664...94,173,568
JBrowse link
G Mtor mechanistic target of rapamycin kinase multiple interactions
increases phosphorylation
ISO puerarin inhibits the reaction [lead nitrate results in increased phosphorylation of MTOR protein] CTD PMID:27762461 NCBI chr 4:148,448,582...148,557,685
Ensembl chr 4:148,448,611...148,557,683
JBrowse link
G Myc myelocytomatosis oncogene multiple interactions EXP lead nitrate affects the reaction [MYC affects the expression of MT1 mRNA]; lead nitrate affects the reaction [MYC affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr15:61,985,341...61,990,361
Ensembl chr15:61,985,391...61,990,374
JBrowse link
G Myh6 myosin, heavy polypeptide 6, cardiac muscle, alpha decreases expression ISO lead nitrate results in decreased expression of MYH6 protein CTD PMID:23391631 NCBI chr14:54,941,921...54,968,017
Ensembl chr14:54,941,921...54,966,927
JBrowse link
G Myh7 myosin, heavy polypeptide 7, cardiac muscle, beta increases expression
multiple interactions
ISO lead nitrate results in increased expression of MYH7 mRNA; lead nitrate results in increased expression of MYH7 protein
resveratrol inhibits the reaction [lead nitrate results in increased expression of MYH7 mRNA]
CTD PMID:23391631 NCBI chr14:54,970,684...54,994,626
Ensembl chr14:54,970,684...54,994,626
JBrowse link
G Ncam1 neural cell adhesion molecule 1 multiple interactions
decreases expression
ISO Ashwagandha inhibits the reaction [lead nitrate results in decreased expression of NCAM1 mRNA]; Ashwagandha inhibits the reaction [lead nitrate results in decreased expression of NCAM1 protein]
lead nitrate results in decreased expression of NCAM1 mRNA; lead nitrate results in decreased expression of NCAM1 protein
CTD PMID:24987671 NCBI chr 9:49,502,129...49,799,393
Ensembl chr 9:49,502,136...49,798,925
JBrowse link
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha decreases expression
multiple interactions
EXP lead nitrate results in decreased expression of NFKBIA protein
mangiferin inhibits the reaction [lead nitrate results in decreased expression of NFKBIA protein]
CTD PMID:23451106 NCBI chr12:55,489,409...55,492,647
Ensembl chr12:55,489,410...55,492,647
JBrowse link
G Nfkbib nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta multiple interactions EXP lead nitrate affects the reaction [NFKBIB affects the expression of MT1 mRNA]; lead nitrate affects the reaction [NFKBIB affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr 7:28,758,251...28,766,644
Ensembl chr 7:28,758,251...28,767,512
JBrowse link
G Nppb natriuretic peptide type B increases expression ISO lead nitrate results in increased expression of NPPB mRNA CTD PMID:23391631 NCBI chr 4:147,985,786...147,987,205
Ensembl chr 4:147,985,788...147,987,205
JBrowse link
G Nqo1 NAD(P)H dehydrogenase, quinone 1 increases expression ISO lead nitrate results in increased expression of NQO1 mRNA CTD PMID:23391631 NCBI chr 8:107,388,225...107,403,205
Ensembl chr 8:107,388,225...107,403,206
JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 decreases expression EXP
ISO
lead nitrate results in decreased expression of NR0B2 mRNA CTD PMID:15475176, PMID:16049268 NCBI chr 4:133,553,376...133,556,686
Ensembl chr 4:133,553,376...133,556,536
JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 decreases expression ISO lead nitrate results in decreased expression of NR1H3 mRNA CTD PMID:15475176 NCBI chr 2:91,184,061...91,202,829
Ensembl chr 2:91,184,061...91,202,834
JBrowse link
G Nr5a2 nuclear receptor subfamily 5, group A, member 2 increases expression EXP lead nitrate results in increased expression of NR5A2 mRNA CTD PMID:16049268 NCBI chr 1:136,842,562...136,960,448
Ensembl chr 1:136,842,571...136,960,448
JBrowse link
G Numb NUMB endocytic adaptor protein multiple interactions EXP lead nitrate affects the reaction [NUMB affects the expression of MT1 mRNA]; lead nitrate affects the reaction [NUMB affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr12:83,794,034...83,921,942
Ensembl chr12:83,794,034...83,921,934
JBrowse link
G Odf1 outer dense fiber of sperm tails 1 decreases expression ISO lead nitrate results in decreased expression of ODF1 mRNA CTD PMID:21628963 NCBI chr15:38,219,203...38,226,735
Ensembl chr15:38,219,203...38,226,735
JBrowse link
G Oxct2a 3-oxoacid CoA transferase 2A decreases expression ISO lead nitrate results in decreased expression of OXCT2A mRNA CTD PMID:21628963 NCBI chr 4:123,321,875...123,323,679
Ensembl chr 4:123,321,875...123,323,634
JBrowse link
G Paqr5 progestin and adipoQ receptor family member V decreases expression ISO lead nitrate results in decreased expression of PAQR5 mRNA CTD PMID:21628963 NCBI chr 9:61,953,738...62,026,852
Ensembl chr 9:61,953,481...62,026,856
JBrowse link
G Pias2 protein inhibitor of activated STAT 2 multiple interactions EXP lead nitrate affects the reaction [PIAS2 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [PIAS2 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr18:77,065,176...77,155,710
Ensembl chr18:77,065,208...77,153,800
JBrowse link
G Pla2g4a phospholipase A2, group IVA (cytosolic, calcium-dependent) multiple interactions
increases expression
ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[lead nitrate results in increased expression of PLA2G4A mRNA] which results in increased secretion of Dinoprostone]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [lead nitrate results in increased expression of PLA2G4A mRNA]; 2-aminoethoxydiphenyl borate inhibits the reaction [lead nitrate results in increased expression of PLA2G4A mRNA]; 4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline inhibits the reaction [[lead nitrate results in increased expression of PLA2G4A mRNA] which results in increased secretion of Dinoprostone]; 4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline inhibits the reaction [lead nitrate results in increased expression of PLA2G4A mRNA]; [lead nitrate results in increased expression of PLA2G4A mRNA] which results in increased secretion of Dinoprostone; EGFR mutant form affects the reaction [[lead nitrate results in increased expression of PLA2G4A mRNA] which results in increased secretion of Dinoprostone]; EGFR mutant form affects the reaction [lead nitrate results in increased expression of PLA2G4A mRNA]; EGFR promotes the reaction [lead nitrate results in increased expression of PLA2G4A mRNA]; RTKI cpd inhibits the reaction [[lead nitrate results in increased expression of PLA2G4A mRNA] which results in increased secretion of Dinoprostone]; RTKI cpd inhibits the reaction [lead nitrate results in increased expression of PLA2G4A mRNA] CTD PMID:20850495 NCBI chr 1:149,829,618...149,961,290
Ensembl chr 1:149,829,618...149,961,290
JBrowse link
G Pold1 polymerase (DNA directed), delta 1, catalytic subunit multiple interactions EXP lead nitrate affects the reaction [POLD1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [POLD1 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr 7:44,532,744...44,548,815
Ensembl chr 7:44,532,746...44,548,849
JBrowse link
G Pou3f3 POU domain, class 3, transcription factor 3 multiple interactions EXP lead nitrate affects the reaction [POU3F3 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [POU3F3 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr 1:42,695,768...42,700,210
Ensembl chr 1:42,694,925...42,703,176
Ensembl chr 1:42,694,925...42,703,176
JBrowse link
G Prm1 protamine 1 decreases expression ISO lead nitrate results in decreased expression of PRM1 mRNA CTD PMID:21628963 NCBI chr16:10,796,332...10,796,823
Ensembl chr16:10,796,326...10,805,839
JBrowse link
G Prm3 protamine 3 decreases expression ISO lead nitrate results in decreased expression of PRM3 mRNA CTD PMID:21628963 NCBI chr16:10,790,508...10,790,914
Ensembl chr16:10,790,505...10,790,914
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases expression
ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[lead nitrate results in increased expression of PTGS2 mRNA] which results in increased secretion of Dinoprostone]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [lead nitrate results in increased expression of PTGS2 mRNA]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [lead nitrate results in increased expression of PTGS2 mRNA]; 4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline inhibits the reaction [[lead nitrate results in increased expression of PTGS2 mRNA] which results in increased secretion of Dinoprostone]; 4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline inhibits the reaction [lead nitrate results in increased expression of PTGS2 mRNA]; 4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline inhibits the reaction [lead nitrate results in increased expression of PTGS2 protein]; [lead nitrate results in increased expression of PTGS2 mRNA] which results in increased secretion of Dinoprostone; Decitabine promotes the reaction [lead nitrate results in increased expression of PTGS2 mRNA]; E2F1 protein inhibits the reaction [lead nitrate results in increased expression of PTGS2 mRNA]; lead nitrate inhibits the reaction [E2F1 protein results in decreased expression of PTGS2 mRNA]; lead nitrate promotes the reaction [RB1 protein results in increased expression of PTGS2 mRNA]; RB1 protein promotes the reaction [lead nitrate results in increased expression of PTGS2 mRNA]; RTKI cpd inhibits the reaction [[lead nitrate results in increased expression of PTGS2 mRNA] which results in increased secretion of Dinoprostone]; RTKI cpd inhibits the reaction [lead nitrate results in increased expression of PTGS2 mRNA]; RTKI cpd inhibits the reaction [lead nitrate results in increased expression of PTGS2 protein]
lead nitrate results in increased expression of PTGS2 mRNA; lead nitrate results in increased expression of PTGS2 protein
CTD PMID:20850495, PMID:21435385, PMID:24639330 NCBI chr 1:150,100,031...150,108,234
Ensembl chr 1:150,100,031...150,108,227
JBrowse link
G Rb1 RB transcriptional corepressor 1 multiple interactions
increases expression
ISO 4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline inhibits the reaction [lead nitrate results in increased expression of RB1 mRNA]; 4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline inhibits the reaction [lead nitrate results in increased expression of RB1 protein]; lead nitrate promotes the reaction [RB1 protein results in increased expression of PTGS2 mRNA]; RB1 protein promotes the reaction [lead nitrate results in increased expression of PTGS2 mRNA]; RTKI cpd inhibits the reaction [lead nitrate results in increased expression of RB1 mRNA]; RTKI cpd inhibits the reaction [lead nitrate results in increased expression of RB1 protein] CTD PMID:24639330 NCBI chr14:73,192,858...73,325,951
Ensembl chr14:73,183,673...73,325,822
JBrowse link
G Rbl2 RB transcriptional corepressor like 2 multiple interactions EXP lead nitrate affects the reaction [RBL2 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [RBL2 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr 8:91,070,057...91,123,844
Ensembl chr 8:91,070,057...91,123,844
JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) multiple interactions
increases expression
EXP mangiferin inhibits the reaction [lead nitrate results in increased expression of RELA protein] CTD PMID:23451106 NCBI chr19:5,637,442...5,648,134
Ensembl chr19:5,637,483...5,648,130
JBrowse link
G Ribc2 RIB43A domain with coiled-coils 2 decreases expression ISO lead nitrate results in decreased expression of RIBC2 mRNA CTD PMID:21628963 NCBI chr15:85,132,060...85,144,570
Ensembl chr15:85,132,078...85,144,570
JBrowse link
G Rps6kb1 ribosomal protein S6 kinase, polypeptide 1 increases phosphorylation
multiple interactions
ISO lead nitrate results in increased phosphorylation of RPS6KB1 protein
puerarin inhibits the reaction [lead nitrate results in increased phosphorylation of RPS6KB1 protein]
CTD PMID:27762461 NCBI chr11:86,498,869...86,544,885
Ensembl chr11:86,498,871...86,544,805
JBrowse link
G Runx1 runt related transcription factor 1 multiple interactions EXP lead nitrate affects the reaction [RUNX1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [RUNX1 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr16:92,601,466...92,826,074
Ensembl chr16:92,601,466...92,826,149
JBrowse link
G Runx2 runt related transcription factor 2 multiple interactions EXP [lead nitrate results in increased abundance of Lead] which results in decreased expression of RUNX2 mRNA; [lead nitrate results in increased abundance of Lead] which results in decreased expression of RUNX2 protein; icaritin inhibits the reaction [[lead nitrate results in increased abundance of Lead] which results in decreased expression of RUNX2 mRNA]; icaritin inhibits the reaction [[lead nitrate results in increased abundance of Lead] which results in decreased expression of RUNX2 protein] CTD PMID:30731080 NCBI chr17:44,495,987...44,814,797
Ensembl chr17:44,495,987...44,814,797
JBrowse link
G Serpina1b serine (or cysteine) preptidase inhibitor, clade A, member 1B multiple interactions EXP lead nitrate affects the reaction [SERPINA1B affects the expression of MT1 mRNA]; lead nitrate affects the reaction [SERPINA1B affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr12:103,728,156...103,738,189
Ensembl chr12:103,728,156...103,830,373
JBrowse link
G Smcp sperm mitochondria-associated cysteine-rich protein decreases expression ISO lead nitrate results in decreased expression of SMCP mRNA CTD PMID:21628963 NCBI chr 3:92,583,866...92,589,073
Ensembl chr 3:92,583,867...92,588,997
JBrowse link
G Snca synuclein, alpha affects localization
multiple interactions
increases expression
EXP lead nitrate affects the localization of SNCA protein
MT1 protein promotes the reaction [lead nitrate results in increased expression of SNCA mRNA]
CTD PMID:19542206 NCBI chr 6:60,731,573...60,829,855
Ensembl chr 6:60,731,575...60,829,855
JBrowse link
G Socs1 suppressor of cytokine signaling 1 multiple interactions EXP lead nitrate affects the reaction [SOCS1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [SOCS1 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr16:10,783,808...10,785,536
Ensembl chr16:10,782,240...10,785,536
JBrowse link
G Sod1 superoxide dismutase 1, soluble multiple interactions
decreases activity
ISO Ashwagandha inhibits the reaction [lead nitrate results in decreased activity of SOD1 protein] CTD PMID:24987671 NCBI chr16:90,220,762...90,226,333
Ensembl chr16:90,220,754...90,226,329
JBrowse link
G Sp3 trans-acting transcription factor 3 multiple interactions
decreases expression
EXP lead nitrate affects the reaction [SP3 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [SP3 affects the expression of MT2 mRNA]
lead nitrate results in decreased expression of SP3 mRNA
CTD PMID:11891201 NCBI chr 2:72,936,430...72,980,446
Ensembl chr 2:72,936,427...72,980,446
JBrowse link
G Spata18 spermatogenesis associated 18 decreases expression ISO lead nitrate results in decreased expression of SPATA18 mRNA CTD PMID:21628963 NCBI chr 5:73,651,380...73,679,584
Ensembl chr 5:73,651,379...73,679,512
JBrowse link
G Spata20 spermatogenesis associated 20 decreases expression ISO lead nitrate results in decreased expression of SPATA20 mRNA CTD PMID:21628963 NCBI chr11:94,478,904...94,485,310
Ensembl chr11:94,478,904...94,486,179
JBrowse link
G Spata21 spermatogenesis associated 21 decreases expression ISO lead nitrate results in decreased expression of SPATA21 mRNA CTD PMID:21628963 NCBI chr 4:141,088,320...141,112,760
Ensembl chr 4:141,088,333...141,112,760
JBrowse link
G Spata6 spermatogenesis associated 6 decreases expression ISO lead nitrate results in decreased expression of SPATA6 mRNA CTD PMID:21628963 NCBI chr 4:111,719,951...111,829,142
Ensembl chr 4:111,719,984...111,829,184
JBrowse link
G Sqstm1 sequestosome 1 multiple interactions
increases expression
EXP
ISO
lead nitrate affects the reaction [SQSTM1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [SQSTM1 affects the expression of MT2 mRNA]
puerarin inhibits the reaction [lead nitrate results in increased expression of SQSTM1 protein]
CTD PMID:11891201, PMID:27762461 NCBI chr11:50,200,152...50,210,820
Ensembl chr11:50,199,366...50,210,827
JBrowse link
G Srebf2 sterol regulatory element binding factor 2 increases expression ISO lead nitrate results in increased expression of SREBF2 mRNA CTD PMID:15475176, PMID:16705668 NCBI chr15:82,147,269...82,205,379
Ensembl chr15:82,147,181...82,205,379
JBrowse link
G Sumo1 small ubiquitin-like modifier 1 multiple interactions EXP lead nitrate affects the reaction [SUMO1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [SUMO1 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr 1:59,639,434...59,670,834
Ensembl chr 1:59,586,558...59,670,834
JBrowse link
G Tbx2 T-box 2 multiple interactions EXP lead nitrate affects the reaction [TBX2 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [TBX2 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr11:85,832,615...85,841,948
Ensembl chr11:85,832,551...85,841,948
JBrowse link
G Tekt2 tektin 2 decreases expression ISO lead nitrate results in decreased expression of TEKT2 mRNA CTD PMID:21628963 NCBI chr 4:126,322,121...126,325,688
Ensembl chr 4:126,322,121...126,325,688
JBrowse link
G Tekt4 tektin 4 decreases expression ISO lead nitrate results in decreased expression of TEKT4 mRNA CTD PMID:21628963 NCBI chr17:25,454,549...25,476,602
Ensembl chr17:25,454,615...25,476,602
JBrowse link
G Tmod1 tropomodulin 1 decreases expression ISO lead nitrate results in decreased expression of TMOD1 mRNA CTD PMID:21628963 NCBI chr 4:46,038,940...46,116,032
Ensembl chr 4:46,038,935...46,116,032
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
EXP
ISO
[IL1A gene mutant form co-treated with IL1B gene mutant form] inhibits the reaction [lead nitrate results in increased expression of TNF mRNA]
Lead nitrate increases expression of Tnf mRNA in liver
CTD PMID:15475176, PMID:16049268, PMID:22293356, PMID:9049203, PMID:7943184 RGD:14995487, RGD:14995476 NCBI chr17:35,199,367...35,202,007
Ensembl chr17:35,199,381...35,202,007
JBrowse link
G Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a multiple interactions EXP lead nitrate affects the reaction [TNFRSF1A affects the expression of MT1 mRNA]; lead nitrate affects the reaction [TNFRSF1A affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr 6:125,349,723...125,362,483
Ensembl chr 6:125,349,362...125,362,484
JBrowse link
G Tnfrsf1b tumor necrosis factor receptor superfamily, member 1b multiple interactions EXP lead nitrate affects the reaction [TNFRSF1B affects the expression of MT1 mRNA]; lead nitrate affects the reaction [TNFRSF1B affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr 4:145,212,368...145,246,870
Ensembl chr 4:145,213,463...145,246,870
JBrowse link
G Tnp1 transition protein 1 decreases expression ISO lead nitrate results in decreased expression of TNP1 mRNA CTD PMID:21628963 NCBI chr 1:73,015,074...73,015,899
Ensembl chr 1:73,015,074...73,015,909
JBrowse link
G Tnp2 transition protein 2 decreases expression ISO lead nitrate results in decreased expression of TNP2 mRNA CTD PMID:21628963 NCBI chr16:10,787,935...10,788,655
Ensembl chr16:10,787,936...10,788,660
JBrowse link
G Tppp2 tubulin polymerization-promoting protein family member 2 decreases expression ISO lead nitrate results in decreased expression of TPPP2 mRNA CTD PMID:21628963 NCBI chr14:51,918,430...51,920,704
Ensembl chr14:51,918,425...51,920,700
JBrowse link
G Trim27 tripartite motif-containing 27 multiple interactions EXP lead nitrate affects the reaction [TRIM27 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [TRIM27 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr13:21,179,450...21,194,723
Ensembl chr13:21,179,445...21,194,724
JBrowse link
G Trp53 transformation related protein 53 multiple interactions ISO [lead nitrate results in increased abundance of Lead] which results in increased expression of TP53 mRNA; titanium dioxide inhibits the reaction [[lead nitrate results in increased abundance of Lead] which results in increased expression of TP53 mRNA] CTD PMID:30738203 NCBI chr11:69,580,348...69,591,873
Ensembl chr11:69,580,359...69,591,873
JBrowse link
G Trpm2 transient receptor potential cation channel, subfamily M, member 2 multiple interactions ISO lead nitrate inhibits the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein] CTD PMID:22750002 NCBI chr10:77,907,722...77,969,909
Ensembl chr10:77,907,722...77,970,563
JBrowse link
G Tsc22d3 TSC22 domain family, member 3 multiple interactions EXP [lead nitrate results in increased abundance of Lead] inhibits the reaction [Hydrocortisone results in increased expression of TSC22D3 mRNA] CTD PMID:29957541 NCBI chr  X:140,539,528...140,600,522
Ensembl chr  X:140,539,528...140,600,659
JBrowse link
G Tsg101 tumor susceptibility gene 101 multiple interactions EXP lead nitrate affects the reaction [TSG101 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [TSG101 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr 7:46,888,949...46,926,320
Ensembl chr 7:46,888,949...46,919,969
JBrowse link
G Tssk2 testis-specific serine kinase 2 decreases expression ISO lead nitrate results in decreased expression of TSSK2 mRNA CTD PMID:21628963 NCBI chr16:17,898,637...17,900,024
Ensembl chr16:17,898,637...17,900,024
JBrowse link
G Tssk3 testis-specific serine kinase 3 decreases expression ISO lead nitrate results in decreased expression of TSSK3 mRNA CTD PMID:21628963 NCBI chr 4:129,489,008...129,491,730
Ensembl chr 4:129,489,014...129,491,022
JBrowse link
G Ttf1 transcription termination factor, RNA polymerase I multiple interactions EXP lead nitrate affects the reaction [TTF1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [TTF1 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr 2:29,060,199...29,087,656
Ensembl chr 2:29,060,262...29,087,656
JBrowse link
G Tuba8 tubulin, alpha 8 decreases expression ISO lead nitrate results in decreased expression of TUBA8 mRNA CTD PMID:21628963 NCBI chr 6:121,210,734...121,226,098
Ensembl chr 6:121,210,696...121,226,854
JBrowse link
G Tulp2 tubby-like protein 2 decreases expression ISO lead nitrate results in decreased expression of TULP2 mRNA CTD PMID:21628963 NCBI chr 7:45,482,026...45,523,646
Ensembl chr 7:45,481,877...45,523,632
JBrowse link
G Wnt3a wingless-type MMTV integration site family, member 3A multiple interactions EXP [lead nitrate results in increased abundance of Lead] which results in decreased expression of WNT3A mRNA; [lead nitrate results in increased abundance of Lead] which results in decreased expression of WNT3A protein; icaritin inhibits the reaction [[lead nitrate results in increased abundance of Lead] which results in decreased expression of WNT3A mRNA]; icaritin inhibits the reaction [[lead nitrate results in increased abundance of Lead] which results in decreased expression of WNT3A protein] CTD PMID:30731080 NCBI chr11:59,248,036...59,290,751
Ensembl chr11:59,248,033...59,290,752
JBrowse link
G Wnt4 wingless-type MMTV integration site family, member 4 multiple interactions EXP lead nitrate affects the reaction [WNT4 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [WNT4 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr 4:137,277,635...137,299,501
Ensembl chr 4:137,277,489...137,299,726
JBrowse link
G Zfhx3 zinc finger homeobox 3 multiple interactions EXP lead nitrate affects the reaction [ZFHX3 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [ZFHX3 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr 8:108,279,311...108,961,636
Ensembl chr 8:107,942,644...108,961,630
JBrowse link
G Znrf4 zinc and ring finger 4 decreases expression ISO lead nitrate results in decreased expression of ZNRF4 mRNA CTD PMID:21628963 NCBI chr17:56,511,248...56,512,483
Ensembl chr17:56,511,248...56,512,431
JBrowse link
potassium nitrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccdc120 coiled-coil domain containing 120 decreases expression ISO potassium nitrate results in decreased expression of CCDC120 mRNA CTD PMID:15878651 NCBI chr  X:7,731,714...7,741,324
Ensembl chr  X:7,731,714...7,750,905
JBrowse link
G Clk1 CDC-like kinase 1 decreases expression ISO potassium nitrate results in decreased expression of CLK1 mRNA CTD PMID:15878651 NCBI chr 1:58,411,988...58,424,088
Ensembl chr 1:58,410,189...58,424,066
JBrowse link
G Dclre1c DNA cross-link repair 1C increases expression ISO potassium nitrate results in increased expression of DCLRE1C mRNA CTD PMID:15878651 NCBI chr 2:3,424,061...3,474,211
Ensembl chr 2:3,424,131...3,464,130
JBrowse link
G Fth1 ferritin heavy polypeptide 1 increases expression ISO potassium nitrate results in increased expression of FTH1 mRNA CTD PMID:15878651 NCBI chr19:9,980,600...9,985,111
Ensembl chr19:9,980,598...9,985,098
JBrowse link
G Ftl1 ferritin light polypeptide 1 increases expression ISO potassium nitrate results in increased expression of FTL mRNA CTD PMID:15878651 NCBI chr 7:45,457,944...45,459,886
Ensembl chr 7:45,457,944...45,459,884
JBrowse link
G Hmgb1 high mobility group box 1 increases expression ISO potassium nitrate results in increased expression of HMGB1 mRNA CTD PMID:15878651 NCBI chr 5:149,046,702...149,053,057
Ensembl chr 5:149,046,702...149,184,489
JBrowse link
G Hmgb2 high mobility group box 2 increases expression ISO potassium nitrate results in increased expression of HMGB2 mRNA CTD PMID:15878651 NCBI chr 8:57,511,843...57,515,999
Ensembl chr 8:57,511,907...57,515,999
JBrowse link
G Pcna proliferating cell nuclear antigen increases expression ISO potassium nitrate results in increased expression of PCNA mRNA CTD PMID:15878651 NCBI chr 2:132,249,286...132,253,180
Ensembl chr 2:132,249,162...132,253,314
JBrowse link
G Septin7 septin 7 decreases expression ISO potassium nitrate results in decreased expression of SEPTIN7 mRNA CTD PMID:15878651 NCBI chr 9:25,251,991...25,308,571
Ensembl chr 9:25,252,439...25,308,571
JBrowse link
G Stmn1 stathmin 1 increases expression ISO potassium nitrate results in increased expression of STMN1 mRNA CTD PMID:15878651 NCBI chr 4:134,468,320...134,473,843
Ensembl chr 4:134,468,320...134,473,843
JBrowse link
G Vegfa vascular endothelial growth factor A decreases expression ISO potassium nitrate results in decreased expression of VEGFA mRNA CTD PMID:15878651 NCBI chr17:46,016,993...46,032,377
Ensembl chr17:46,016,993...46,032,369
JBrowse link
silver(1+) nitrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 increases response to substance
multiple interactions
ISO ABCC1 protein results in increased susceptibility to Silver Nitrate
[ABCC1 protein results in increased susceptibility to Silver Nitrate] which results in decreased export of calcein AM
CTD PMID:27376922 NCBI chr16:14,361,453...14,474,878
Ensembl chr16:14,361,558...14,475,737
JBrowse link
G Atm ataxia telangiectasia mutated increases expression ISO Silver Nitrate analog results in increased expression of ATM mRNA CTD PMID:22831968 NCBI chr 9:53,437,122...53,536,828
Ensembl chr 9:53,439,149...53,536,740
JBrowse link
G Atr ataxia telangiectasia and Rad3 related increases expression ISO Silver Nitrate analog results in increased expression of ATR mRNA CTD PMID:22831968 NCBI chr 9:95,857,597...95,953,217
Ensembl chr 9:95,857,597...95,951,781
JBrowse link
G Aurka aurora kinase A increases expression
multiple interactions
ISO Silver Nitrate results in increased expression of AURKA protein modified form
CFL1 mRNA promotes the reaction [Silver Nitrate results in increased expression of AURKA protein modified form]
CTD PMID:28499611 NCBI chr 2:172,356,190...172,370,886
Ensembl chr 2:172,356,190...172,370,535
JBrowse link
G Aurkb aurora kinase B increases phosphorylation
multiple interactions
ISO Silver Nitrate results in increased phosphorylation of AURKB protein
CFL1 mRNA promotes the reaction [Silver Nitrate results in increased phosphorylation of AURKB protein]
CTD PMID:28499611 NCBI chr11:69,045,624...69,051,664
Ensembl chr11:69,045,647...69,051,664
JBrowse link
G Aurkc aurora kinase C multiple interactions
increases expression
ISO CFL1 mRNA promotes the reaction [Silver Nitrate results in increased expression of AURKC protein modified form] CTD PMID:28499611 NCBI chr 7:6,995,347...7,003,091
Ensembl chr 7:6,995,300...7,003,091
JBrowse link
G Bub1 BUB1, mitotic checkpoint serine/threonine kinase increases expression ISO Silver Nitrate analog results in increased expression of BUB1 mRNA; Silver Nitrate results in increased expression of BUB1 mRNA CTD PMID:22831968 NCBI chr 2:127,800,197...127,831,859
Ensembl chr 2:127,801,122...127,831,865
JBrowse link
G Bub1b BUB1B, mitotic checkpoint serine/threonine kinase increases expression ISO Silver Nitrate analog results in increased expression of BUB1B mRNA; Silver Nitrate results in increased expression of BUB1B mRNA CTD PMID:22831968 NCBI chr 2:118,598,202...118,641,592
Ensembl chr 2:118,598,211...118,641,591
JBrowse link
G Cat catalase increases expression ISO Silver Nitrate results in increased expression of CAT mRNA CTD PMID:19508889 NCBI chr 2:103,453,904...103,485,153
Ensembl chr 2:103,453,849...103,485,160
JBrowse link
G Ccna2 cyclin A2 decreases expression ISO Silver Nitrate analog results in decreased expression of CCNA2 mRNA CTD PMID:22831968 NCBI chr 3:36,564,865...36,573,038
Ensembl chr 3:36,564,865...36,572,150
JBrowse link
G Ccnb1 cyclin B1 decreases expression ISO Silver Nitrate analog results in decreased expression of CCNB1 mRNA; Silver Nitrate results in decreased expression of CCNB1 mRNA CTD PMID:22831968 NCBI chr13:100,778,739...100,786,486
Ensembl chr13:100,778,650...100,786,570
JBrowse link
G Ccne1 cyclin E1 increases expression ISO Silver Nitrate analog results in increased expression of CCNE1 mRNA; Silver Nitrate results in increased expression of CCNE1 mRNA CTD PMID:22831968 NCBI chr 7:38,097,984...38,107,490
Ensembl chr 7:38,097,984...38,107,534
JBrowse link
G Cd28 CD28 antigen multiple interactions
affects response to substance
EXP CD28 protein affects the reaction [Silver Nitrate results in decreased activity of FBL protein]
CD28 protein affects the susceptibility to Silver Nitrate
CTD PMID:19077085 NCBI chr 1:60,746,388...60,773,359
Ensembl chr 1:60,716,800...60,773,359
JBrowse link
G Cdc14a CDC14 cell division cycle 14A increases expression ISO Silver Nitrate analog results in increased expression of CDC14A mRNA CTD PMID:22831968 NCBI chr 3:116,272,553...116,428,741
Ensembl chr 3:116,272,553...116,428,745
JBrowse link
G Cdc25b cell division cycle 25B affects expression ISO Silver Nitrate analog affects the expression of CDC25B mRNA CTD PMID:22831968 NCBI chr 2:131,186,436...131,198,511
Ensembl chr 2:131,186,949...131,198,497
JBrowse link
G Cdc25c cell division cycle 25C affects expression ISO Silver Nitrate analog affects the expression of CDC25C mRNA CTD PMID:22831968 NCBI chr18:34,732,993...34,751,564
Ensembl chr18:34,732,993...34,751,533
JBrowse link
G Cdc45 cell division cycle 45 increases expression ISO Silver Nitrate analog results in increased expression of CDC45 mRNA; Silver Nitrate results in increased expression of CDC45 mRNA CTD PMID:22831968 NCBI chr16:18,780,447...18,811,972
Ensembl chr16:18,780,447...18,811,987
JBrowse link
G Cdc6 cell division cycle 6 increases expression ISO Silver Nitrate analog results in increased expression of CDC6 mRNA; Silver Nitrate results in increased expression of CDC6 mRNA CTD PMID:22831968 NCBI chr11:98,907,709...98,923,942
Ensembl chr11:98,907,801...98,923,940
JBrowse link
G Cdc7 cell division cycle 7 (S. cerevisiae) affects expression
increases expression
ISO Silver Nitrate analog affects the expression of CDC7 mRNA
Silver Nitrate results in increased expression of CDC7 mRNA
CTD PMID:22831968 NCBI chr 5:106,964,315...106,984,440
Ensembl chr 5:106,964,322...106,984,432
JBrowse link
G Cdk1 cyclin-dependent kinase 1 affects expression ISO Silver Nitrate analog affects the expression of CDK1 mRNA CTD PMID:22831968 NCBI chr10:69,335,146...69,352,912
Ensembl chr10:69,335,146...69,352,938
JBrowse link
G Cdkn2a cyclin dependent kinase inhibitor 2A increases expression ISO Silver Nitrate results in increased expression of CDKN2A mRNA CTD PMID:22831968 NCBI chr 4:89,274,473...89,294,619
Ensembl chr 4:89,274,471...89,294,653
JBrowse link
G Cdkn2c cyclin dependent kinase inhibitor 2C affects expression ISO Silver Nitrate analog affects the expression of CDKN2C mRNA CTD PMID:22831968 NCBI chr 4:109,660,876...109,666,756
Ensembl chr 4:109,660,876...109,667,189
JBrowse link
G Cfl1 cofilin 1, non-muscle multiple interactions ISO CFL1 mRNA promotes the reaction [Silver Nitrate results in increased expression of AURKA protein modified form]; CFL1 mRNA promotes the reaction [Silver Nitrate results in increased expression of AURKC protein modified form]; CFL1 mRNA promotes the reaction [Silver Nitrate results in increased phosphorylation of AURKB protein] CTD PMID:28499611 NCBI chr19:5,490,455...5,494,031
Ensembl chr19:5,490,455...5,495,201
JBrowse link
G Chek1 checkpoint kinase 1 increases expression ISO Silver Nitrate analog results in increased expression of CHEK1 mRNA CTD PMID:22831968 NCBI chr 9:36,708,482...36,726,658
Ensembl chr 9:36,708,482...36,727,065
JBrowse link
G Chek2 checkpoint kinase 2 increases expression ISO Silver Nitrate analog results in increased expression of CHEK2 mRNA CTD PMID:22831968 NCBI chr 5:110,839,800...110,874,140
Ensembl chr 5:110,839,979...110,874,145
JBrowse link
G Cxcl15 chemokine (C-X-C motif) ligand 15 increases expression ISO Silver Nitrate results in increased expression of CXCL8 mRNA CTD PMID:20491607 NCBI chr 5:90,794,534...90,803,067
Ensembl chr 5:90,794,534...90,803,067
JBrowse link
G Dbf4 DBF4 zinc finger increases expression ISO Silver Nitrate analog results in increased expression of DBF4 mRNA; Silver Nitrate results in increased expression of DBF4 mRNA CTD PMID:22831968 NCBI chr 5:8,396,969...8,422,725
Ensembl chr 5:8,396,973...8,422,716
JBrowse link
G Dnaja1 DnaJ heat shock protein family (Hsp40) member A1 increases expression ISO Silver Nitrate analog results in increased expression of DNAJA1 mRNA CTD PMID:22831968 NCBI chr 4:40,722,468...40,734,965
Ensembl chr 4:40,722,150...40,737,149
JBrowse link
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 increases expression ISO Silver Nitrate analog results in increased expression of DNAJB1 mRNA CTD PMID:22831968 NCBI chr 8:83,608,175...83,612,653
Ensembl chr 8:83,608,193...83,612,653
JBrowse link
G Dnajc19 DnaJ heat shock protein family (Hsp40) member C19 decreases expression ISO Silver Nitrate analog results in decreased expression of DNAJC19 mRNA CTD PMID:22831968 NCBI chr 3:34,057,280...34,081,354
Ensembl chr 3:34,056,020...34,081,321
JBrowse link
G E2f1 E2F transcription factor 1 increases expression ISO Silver Nitrate analog results in increased expression of E2F1 mRNA CTD PMID:22831968 NCBI chr 2:154,559,400...154,569,892
Ensembl chr 2:154,559,407...154,569,892
JBrowse link
G E2f2 E2F transcription factor 2 increases expression ISO Silver Nitrate analog results in increased expression of E2F2 mRNA CTD PMID:22831968 NCBI chr 4:136,172,274...136,196,057
Ensembl chr 4:136,172,394...136,196,057
JBrowse link
G E2f3 E2F transcription factor 3 increases expression ISO Silver Nitrate analog results in increased expression of E2F3 mRNA CTD PMID:22831968 NCBI chr13:29,906,575...29,986,064
Ensembl chr13:29,906,575...29,986,063
JBrowse link
G E2f4 E2F transcription factor 4 increases expression ISO Silver Nitrate results in increased expression of E2F4 mRNA CTD PMID:22831968 NCBI chr 8:105,297,663...105,305,370
Ensembl chr 8:105,297,663...105,305,370
JBrowse link
G E2f5 E2F transcription factor 5 increases expression ISO Silver Nitrate results in increased expression of E2F5 mRNA CTD PMID:22831968 NCBI chr 3:14,578,602...14,606,309
Ensembl chr 3:14,578,641...14,606,309
JBrowse link
G Fbl fibrillarin multiple interactions
decreases activity
EXP CD28 protein affects the reaction [Silver Nitrate results in decreased activity of FBL protein]; IFNG protein affects the reaction [Silver Nitrate results in decreased activity of FBL protein]; IL4 protein affects the reaction [Silver Nitrate results in decreased activity of FBL protein]; IL6 protein affects the reaction [Silver Nitrate results in decreased activity of FBL protein] CTD PMID:19077085 NCBI chr 7:28,168,893...28,179,269
Ensembl chr 7:28,169,710...28,179,269
JBrowse link
G Fos FBJ osteosarcoma oncogene increases expression ISO Silver Nitrate results in increased expression of FOS mRNA CTD PMID:10362023 NCBI chr12:85,473,890...85,477,274
Ensembl chr12:85,473,890...85,477,273
JBrowse link
G Fosb FBJ osteosarcoma oncogene B decreases expression ISO Silver Nitrate results in decreased expression of FOSB mRNA CTD PMID:27180073 NCBI chr 7:19,302,696...19,310,118
Ensembl chr 7:19,302,696...19,310,051
JBrowse link
G G6pdx glucose-6-phosphate dehydrogenase X-linked decreases activity ISO Silver Nitrate results in decreased activity of G6PD protein CTD PMID:28557068 NCBI chr  X:74,409,483...74,428,880
Ensembl chr  X:74,409,483...74,429,194
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit decreases expression ISO Silver Nitrate results in decreased expression of GCLC mRNA CTD PMID:19733233 NCBI chr 9:77,754,535...77,794,489
Ensembl chr 9:77,754,535...77,794,485
JBrowse link
G Gpx1 glutathione peroxidase 1 increases expression ISO Silver Nitrate results in increased expression of GPX1 mRNA CTD PMID:19508889 NCBI chr 9:108,339,080...108,340,342
Ensembl chr 9:108,338,903...108,340,343
JBrowse link
G Gpx7 glutathione peroxidase 7 increases expression ISO Silver Nitrate results in increased expression of GPX7 mRNA CTD PMID:27180073 NCBI chr 4:108,400,217...108,406,713
Ensembl chr 4:108,400,390...108,406,961
JBrowse link
G H1f3 H1.3 linker histone, cluster member decreases expression ISO Silver Nitrate analog results in decreased expression of H1-3 mRNA CTD PMID:22831968 NCBI chr13:23,555,032...23,555,807
Ensembl chr13:23,553,262...23,560,686
JBrowse link
G H1f5 H1.5 linker histone, cluster member decreases expression ISO Silver Nitrate analog results in decreased expression of H1-5 mRNA; Silver Nitrate results in decreased expression of H1-5 mRNA CTD PMID:22831968 NCBI chr13:21,779,832...21,780,625
Ensembl chr13:21,779,883...21,780,625
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression
ISO Silver Nitrate promotes the reaction [HSF1 protein binds to HMOX1 promoter]
Silver Nitrate results in increased expression of HMOX1 mRNA
CTD PMID:17244614, PMID:27180073 NCBI chr 8:75,093,618...75,100,593
Ensembl chr 8:75,093,621...75,100,589
JBrowse link
G Hsf1 heat shock factor 1 multiple interactions
increases activity
ISO Silver Nitrate promotes the reaction [HSF1 protein binds to HMOX1 promoter]; Silver Nitrate promotes the reaction [HSF1 protein binds to HSPA1A enhancer]; Silver Nitrate promotes the reaction [HSF1 protein binds to HSPA1A promoter]
Silver Nitrate results in increased activity of HSF1 protein
CTD PMID:16460681, PMID:17244614 NCBI chr15:76,477,362...76,501,155
Ensembl chr15:76,477,422...76,501,913
JBrowse link
G Hsp90aa1 heat shock protein 90, alpha (cytosolic), class A member 1 increases expression ISO Silver Nitrate analog results in increased expression of HSP90AA1 mRNA CTD PMID:22831968 NCBI chr12:110,691,036...110,696,395
Ensembl chr12:110,690,605...110,702,728
JBrowse link
G Hspa12a heat shock protein 12A decreases expression ISO Silver Nitrate analog results in decreased expression of HSPA12A mRNA CTD PMID:22831968 NCBI chr19:58,795,750...58,943,672
Ensembl chr19:58,795,750...58,943,654
JBrowse link
G Hspa12b heat shock protein 12B increases expression ISO Silver Nitrate analog results in increased expression of HSPA12B mRNA CTD PMID:22831968 NCBI chr 2:131,127,412...131,145,985
Ensembl chr 2:131,127,280...131,146,321
JBrowse link
G Hspa1a heat shock protein 1A multiple interactions
increases expression
ISO Silver Nitrate promotes the reaction [HSF1 protein binds to HSPA1A enhancer]; Silver Nitrate promotes the reaction [HSF1 protein binds to HSPA1A promoter]
Silver Nitrate results in increased expression of HSPA1A mRNA
CTD PMID:16460681, PMID:17244614, PMID:27180073 NCBI chr17:34,969,359...34,972,156
Ensembl chr17:34,969,190...34,972,156
JBrowse link
G Hspb11 heat shock protein family B (small), member 11 decreases expression ISO Silver Nitrate analog results in decreased expression of HSPB11 mRNA CTD PMID:22831968 NCBI chr 4:107,253,593...107,284,497
Ensembl chr 4:107,253,593...107,279,938
JBrowse link
G Hspb9 heat shock protein, alpha-crystallin-related, B9 increases expression ISO Silver Nitrate analog results in increased expression of HSPB9 mRNA CTD PMID:22831968 NCBI chr11:100,713,929...100,714,575
Ensembl chr11:100,713,850...100,714,575
JBrowse link
G Hsph1 heat shock 105kDa/110kDa protein 1 increases expression ISO Silver Nitrate analog results in increased expression of HSPH1 mRNA CTD PMID:22831968 NCBI chr 5:149,616,843...149,636,498
Ensembl chr 5:149,614,287...149,636,376
JBrowse link
G Ifng interferon gamma affects response to substance
multiple interactions
EXP IFNG protein affects the susceptibility to Silver Nitrate
IFNG protein affects the reaction [Silver Nitrate results in decreased activity of FBL protein]
CTD PMID:19077085 NCBI chr10:118,441,046...118,445,894
Ensembl chr10:118,441,046...118,445,892
JBrowse link
G Il1b interleukin 1 beta increases expression EXP Silver Nitrate results in increased expression of IL1B protein CTD PMID:25527144 NCBI chr 2:129,364,569...129,371,164
Ensembl chr 2:129,364,570...129,371,139
JBrowse link
G Il4 interleukin 4 affects response to substance
multiple interactions
EXP IL4 protein affects the susceptibility to Silver Nitrate
IL4 protein affects the reaction [Silver Nitrate results in decreased activity of FBL protein]
CTD PMID:19077085 NCBI chr11:53,612,460...53,618,665
Ensembl chr11:53,602,982...53,618,669
JBrowse link
G Il6 interleukin 6 affects response to substance
multiple interactions
EXP IL6 protein affects the susceptibility to Silver Nitrate
IL6 protein affects the reaction [Silver Nitrate results in decreased activity of FBL protein]
CTD PMID:19077085 NCBI chr 5:30,013,114...30,019,975
Ensembl chr 5:30,013,114...30,019,981
JBrowse link
G Kitl kit ligand increases expression ISO Silver Nitrate results in increased expression of KITLG mRNA CTD PMID:22831968 NCBI chr10:100,015,615...100,100,416
Ensembl chr10:100,015,630...100,100,416
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 increases phosphorylation EXP Silver Nitrate results in increased phosphorylation of MAPK1 protein CTD PMID:27624343 NCBI chr16:16,983,382...17,047,453
Ensembl chr16:16,983,382...17,047,453
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 increases phosphorylation EXP Silver Nitrate results in increased phosphorylation of MAPK3 protein CTD PMID:27624343 NCBI chr 7:126,759,626...126,765,816
Ensembl chr 7:126,759,601...126,765,819
JBrowse link
G Mcm3 minichromosome maintenance complex component 3 decreases expression ISO Silver Nitrate analog results in decreased expression of MCM3 mRNA CTD PMID:22831968 NCBI chr 1:20,802,966...20,820,312
Ensembl chr 1:20,802,968...20,820,312
JBrowse link
G Mcm4 minichromosome maintenance complex component 4 increases expression ISO Silver Nitrate results in increased expression of MCM4 mRNA CTD PMID:22831968 NCBI chr16:15,623,897...15,637,400
Ensembl chr16:15,623,897...15,637,400
JBrowse link
G Mcm6 minichromosome maintenance complex component 6 increases expression ISO Silver Nitrate results in increased expression of MCM6 mRNA CTD PMID:22831968 NCBI chr 1:128,331,575...128,359,705
Ensembl chr 1:128,331,590...128,359,664
JBrowse link
G Mt1 metallothionein 1 increases expression EXP
ISO
Silver Nitrate results in increased expression of MT1 mRNA
Silver Nitrate analog results in increased expression of MT1X mRNA; Silver Nitrate results in increased expression of MT1X mRNA
CTD PMID:22831968, PMID:27180073, PMID:27624343 NCBI chr 8:94,178,883...94,180,327
Ensembl chr 8:94,179,082...94,180,327
JBrowse link
G Mt2 metallothionein 2 increases expression ISO
EXP
Silver Nitrate results in increased expression of MT2A mRNA
Silver Nitrate results in increased expression of MT2 mRNA
CTD PMID:10362023, PMID:20491607, PMID:23333424, PMID:27180073, PMID:27624343 NCBI chr 8:94,172,618...94,173,567
Ensembl chr 8:94,172,664...94,173,568
JBrowse link
G Mt3 metallothionein 3 increases expression ISO Silver Nitrate analog results in increased expression of MT3 mRNA CTD PMID:22831968 NCBI chr 8:94,152,607...94,154,148
Ensembl chr 8:94,152,607...94,154,146
JBrowse link
G Mt4 metallothionein 4 increases expression ISO Silver Nitrate analog results in increased expression of MT4 mRNA; Silver Nitrate results in increased expression of MT4 mRNA CTD PMID:22831968 NCBI chr 8:94,137,204...94,139,031
Ensembl chr 8:94,137,197...94,139,031
JBrowse link
G Mtf1 metal response element binding transcription factor 1 multiple interactions
increases activity
ISO MTF1 mutant form inhibits the reaction [Silver Nitrate results in increased expression of MT1A mRNA]; MTF1 mutant form inhibits the reaction [Silver Nitrate results in increased expression of SLC30A1 mRNA]
Silver Nitrate results in increased activity of MTF1 protein
CTD PMID:19733233 NCBI chr 4:124,802,549...124,849,800
Ensembl chr 4:124,802,104...124,849,800
JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 decreases expression
increases activity
ISO Silver Nitrate results in decreased expression of NFE2L2 mRNA
Silver Nitrate results in increased activity of NFE2L2 protein
CTD PMID:19733233, PMID:23872425 NCBI chr 2:75,675,513...75,704,663
Ensembl chr 2:75,675,513...75,704,641
JBrowse link
G Orc6 origin recognition complex, subunit 6 increases expression ISO Silver Nitrate results in increased expression of ORC6 mRNA CTD PMID:22831968 NCBI chr 8:85,299,632...85,308,279
Ensembl chr 8:85,299,632...85,308,278
JBrowse link
G Pcna proliferating cell nuclear antigen increases expression ISO Silver Nitrate analog results in increased expression of PCNA mRNA; Silver Nitrate results in increased expression of PCNA mRNA CTD PMID:22831968 NCBI chr 2:132,249,286...132,253,180
Ensembl chr 2:132,249,162...132,253,314
JBrowse link
G Plk1 polo like kinase 1 decreases expression ISO Silver Nitrate analog results in decreased expression of PLK1 mRNA CTD PMID:22831968 NCBI chr 7:122,159,435...122,169,884
Ensembl chr 7:122,159,439...122,169,873
JBrowse link
G Pttg1 pituitary tumor-transforming gene 1 increases expression
affects expression
ISO Silver Nitrate results in increased expression of PTTG1 mRNA
Silver Nitrate analog affects the expression of PTTG1 mRNA
CTD PMID:22831968 NCBI chr11:43,420,244...43,427,463
Ensembl chr11:43,420,250...43,426,251
JBrowse link
G Rbl1 RB transcriptional corepressor like 1 increases expression ISO Silver Nitrate analog results in increased expression of RBL1 mRNA; Silver Nitrate results in increased expression of RBL1 mRNA CTD PMID:22831968 NCBI chr 2:157,145,893...157,204,534
Ensembl chr 2:157,145,893...157,204,534
JBrowse link
G Rbl2 RB transcriptional corepressor like 2 increases expression ISO Silver Nitrate analog results in increased expression of RBL2 mRNA; Silver Nitrate results in increased expression of RBL2 mRNA CTD PMID:22831968 NCBI chr 8:91,070,057...91,123,844
Ensembl chr 8:91,070,057...91,123,844
JBrowse link
G Skp2 S-phase kinase-associated protein 2 increases expression ISO Silver Nitrate analog results in increased expression of SKP2 mRNA CTD PMID:22831968 NCBI chr15:9,111,982...9,155,425
Ensembl chr15:9,111,985...9,155,425
JBrowse link
G Slc30a1 solute carrier family 30 (zinc transporter), member 1 multiple interactions
increases expression
ISO MTF1 mutant form inhibits the reaction [Silver Nitrate results in increased expression of SLC30A1 mRNA] CTD PMID:19733233 NCBI chr 1:191,906,697...191,913,248
Ensembl chr 1:191,906,767...191,913,247
JBrowse link
G Slc31a1 solute carrier family 31, member 1 increases expression ISO Silver Nitrate results in increased expression of SLC31A1 mRNA CTD PMID:24132751 NCBI chr 4:62,360,583...62,391,769
Ensembl chr 4:62,360,727...62,391,769
JBrowse link
G Smad2 SMAD family member 2 decreases expression
increases expression
ISO Silver Nitrate analog results in decreased expression of SMAD2 mRNA
Silver Nitrate results in increased expression of SMAD2 mRNA
CTD PMID:22831968 NCBI chr18:76,241,090...76,311,748
Ensembl chr18:76,241,580...76,310,963
JBrowse link
G Smad3 SMAD family member 3 decreases expression
increases expression
ISO Silver Nitrate analog results in decreased expression of SMAD3 mRNA
Silver Nitrate results in increased expression of SMAD3 mRNA
CTD PMID:22831968 NCBI chr 9:63,646,766...63,757,994
Ensembl chr 9:63,646,767...63,757,994
JBrowse link
G Sod1 superoxide dismutase 1, soluble increases expression ISO Silver Nitrate results in increased expression of SOD1 mRNA CTD PMID:19508889 NCBI chr16:90,220,762...90,226,333
Ensembl chr16:90,220,754...90,226,329
JBrowse link
G Sp1 trans-acting transcription factor 1 increases expression ISO Silver Nitrate results in increased expression of SP1 mRNA CTD PMID:24132751 NCBI chr15:102,406,316...102,436,404
Ensembl chr15:102,406,143...102,436,404
JBrowse link
G Tfdp1 transcription factor Dp 1 increases expression ISO Silver Nitrate analog results in increased expression of TFDP1 mRNA CTD PMID:22831968 NCBI chr 8:13,338,725...13,378,448
Ensembl chr 8:13,338,751...13,378,448
JBrowse link
G Tfdp2 transcription factor Dp 2 increases expression ISO Silver Nitrate analog results in increased expression of TFDP2 mRNA CTD PMID:22831968 NCBI chr 9:96,196,246...96,323,646
Ensembl chr 9:96,196,275...96,323,646
JBrowse link
G Tpo thyroid peroxidase increases expression ISO Silver Nitrate results in increased expression of TPO mRNA CTD PMID:27180073 NCBI chr12:30,054,659...30,132,984
Ensembl chr12:30,054,659...30,132,624
JBrowse link
G Trp53 transformation related protein 53 decreases expression ISO Silver Nitrate analog results in decreased expression of TP53 mRNA CTD PMID:22831968 NCBI chr11:69,580,348...69,591,873
Ensembl chr11:69,580,359...69,591,873
JBrowse link
sodium nitrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acadl acyl-Coenzyme A dehydrogenase, long-chain multiple interactions EXP sodium nitrate inhibits the reaction [Doxorubicin results in increased expression of ACADL protein] CTD PMID:21251210 NCBI chr 1:66,830,839...66,863,309
Ensembl chr 1:66,830,839...66,863,277
JBrowse link
G Actc1 actin, alpha, cardiac muscle 1 multiple interactions EXP sodium nitrate inhibits the reaction [Doxorubicin results in increased expression of ACTC1 protein] CTD PMID:21251210 NCBI chr 2:114,047,282...114,052,875
Ensembl chr 2:114,047,282...114,053,548
JBrowse link
G Afp alpha fetoprotein multiple interactions EXP sodium nitrate inhibits the reaction [Doxorubicin results in decreased expression of AFP protein] CTD PMID:21251210 NCBI chr 5:90,490,714...90,508,907
Ensembl chr 5:90,490,737...90,508,907
JBrowse link
G Atp5b ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit multiple interactions EXP sodium nitrate inhibits the reaction [Doxorubicin results in increased expression of ATP5B protein] CTD PMID:21251210 NCBI chr10:128,083,307...128,090,388
Ensembl chr10:128,083,273...128,090,391
JBrowse link
G Atp5h ATP synthase, H+ transporting, mitochondrial F0 complex, subunit D multiple interactions EXP sodium nitrate inhibits the reaction [Doxorubicin results in increased expression of ATP5H protein] CTD PMID:21251210 NCBI chr11:115,415,691...115,419,919
Ensembl chr11:115,415,689...115,419,962
JBrowse link
G Cacna2d1 calcium channel, voltage-dependent, alpha2/delta subunit 1 increases expression EXP sodium nitrate results in increased expression of CACNA2D1 protein CTD PMID:22687611 NCBI chr 5:15,934,264...16,374,511
Ensembl chr 5:15,934,691...16,374,511
JBrowse link
G Casq1 calsequestrin 1 increases expression EXP sodium nitrate results in increased expression of CASQ1 protein CTD PMID:22687611 NCBI chr 1:172,209,894...172,219,895
Ensembl chr 1:172,209,894...172,219,868
JBrowse link
G Cat catalase decreases activity ISO sodium nitrate results in decreased activity of CAT protein CTD PMID:24740966 NCBI chr 2:103,453,904...103,485,153
Ensembl chr 2:103,453,849...103,485,160
JBrowse link
G Cox4i1 cytochrome c oxidase subunit 4I1 multiple interactions EXP sodium nitrate inhibits the reaction [Doxorubicin results in increased expression of COX4I1 protein] CTD PMID:21251210 NCBI chr 8:120,668,225...120,674,209
Ensembl chr 8:120,668,222...120,674,207
JBrowse link
G Cryab crystallin, alpha B multiple interactions EXP sodium nitrate inhibits the reaction [Doxorubicin results in increased expression of CRYAB protein] CTD PMID:21251210 NCBI chr 9:50,745,951...50,756,636
Ensembl chr 9:50,751,325...50,756,636
JBrowse link
G Fabp3 fatty acid binding protein 3, muscle and heart multiple interactions EXP sodium nitrate inhibits the reaction [Doxorubicin results in increased expression of FABP3 protein] CTD PMID:21251210 NCBI chr 4:130,308,738...130,315,463
Ensembl chr 4:130,308,595...130,315,463
JBrowse link
G Fth1 ferritin heavy polypeptide 1 multiple interactions EXP sodium nitrate inhibits the reaction [Doxorubicin results in decreased expression of FTH1 protein] CTD PMID:21251210 NCBI chr19:9,980,600...9,985,111
Ensembl chr19:9,980,598...9,985,098
JBrowse link
G G6pdx glucose-6-phosphate dehydrogenase X-linked decreases activity ISO sodium nitrate results in decreased activity of G6PD protein CTD PMID:19922758 NCBI chr  X:74,409,483...74,428,880
Ensembl chr  X:74,409,483...74,429,194
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1, soluble multiple interactions EXP sodium nitrate inhibits the reaction [Doxorubicin results in increased expression of GOT1 protein] CTD PMID:21251210 NCBI chr19:43,499,752...43,524,605
Ensembl chr19:43,499,752...43,524,605
JBrowse link
G Gsr glutathione reductase multiple interactions EXP [Quercetin co-treated with sodium nitrate] results in increased activity of GSR protein CTD PMID:24860958 NCBI chr 8:33,653,238...33,698,162
Ensembl chr 8:33,652,523...33,698,163
JBrowse link
G Idh3a isocitrate dehydrogenase 3 (NAD+) alpha multiple interactions EXP sodium nitrate inhibits the reaction [Doxorubicin results in increased expression of IDH3A protein] CTD PMID:21251210 NCBI chr 9:54,586,511...54,604,662
Ensembl chr 9:54,586,334...54,604,661
JBrowse link
G Ldhc lactate dehydrogenase C decreases activity ISO sodium nitrate results in decreased activity of LDHC protein CTD PMID:19922758 NCBI chr 7:46,861,263...46,878,147
Ensembl chr 7:46,861,203...46,878,142
JBrowse link
G Mb myoglobin multiple interactions EXP sodium nitrate inhibits the reaction [Doxorubicin results in increased expression of MB protein] CTD PMID:21251210 NCBI chr15:77,015,487...77,050,668
Ensembl chr15:77,015,487...77,050,670
JBrowse link
G Mpo myeloperoxidase multiple interactions ISO sodium nitrate inhibits the reaction [Diclofenac results in increased activity of MPO protein] CTD PMID:17275683 NCBI chr11:87,793,784...87,804,412
Ensembl chr11:87,793,581...87,804,413
JBrowse link
G Muc6 mucin 6, gastric increases expression ISO sodium nitrate results in increased expression of MUC6 mRNA CTD PMID:17275683 NCBI chr 7:141,633,459...141,655,393
Ensembl chr 7:141,633,456...141,655,319
JBrowse link
G Myh6 myosin, heavy polypeptide 6, cardiac muscle, alpha multiple interactions EXP sodium nitrate inhibits the reaction [Doxorubicin results in decreased expression of MYH6 protein] CTD PMID:21251210 NCBI chr14:54,941,921...54,968,017
Ensembl chr14:54,941,921...54,966,927
JBrowse link
G Myl2 myosin, light polypeptide 2, regulatory, cardiac, slow multiple interactions EXP [sodium nitrate co-treated with Doxorubicin] results in decreased expression of MYL2 protein; sodium nitrate inhibits the reaction [Doxorubicin results in increased expression of MYL2 protein] CTD PMID:21251210 NCBI chr 5:122,092,724...122,113,473
Ensembl chr 5:122,100,951...122,113,472
JBrowse link
G Myl3 myosin, light polypeptide 3 multiple interactions EXP sodium nitrate inhibits the reaction [Doxorubicin results in increased expression of MYL3 protein] CTD PMID:21251210 NCBI chr 9:110,763,678...110,769,802
Ensembl chr 9:110,741,861...110,769,798
JBrowse link
G Myoz2 myozenin 2 multiple interactions EXP sodium nitrate inhibits the reaction [Doxorubicin results in increased expression of MYOZ2 protein] CTD PMID:21251210 NCBI chr 3:123,006,206...123,035,003
Ensembl chr 3:123,006,206...123,035,015
JBrowse link
G Nos2 nitric oxide synthase 2, inducible multiple interactions ISO sodium nitrate inhibits the reaction [Diclofenac results in increased expression of NOS2 mRNA] CTD PMID:17275683 NCBI chr11:78,920,787...78,960,226
Ensembl chr11:78,920,787...78,960,254
JBrowse link
G Nos3 nitric oxide synthase 3, endothelial cell multiple interactions EXP sodium nitrate inhibits the reaction [NOS3 gene mutant form results in increased abundance of Triglycerides] CTD PMID:20876122 NCBI chr 5:24,364,816...24,384,474
Ensembl chr 5:24,364,810...24,384,474
JBrowse link
G Pkm pyruvate kinase, muscle multiple interactions EXP sodium nitrate inhibits the reaction [Doxorubicin results in increased expression of PKM protein] CTD PMID:21251210 NCBI chr 9:59,656,576...59,679,372
Ensembl chr 9:59,656,368...59,679,375
JBrowse link
G Prdx3 peroxiredoxin 3 multiple interactions EXP sodium nitrate inhibits the reaction [Doxorubicin results in increased expression of PRDX3 protein] CTD PMID:21251210 NCBI chr19:60,864,066...60,874,538
Ensembl chr19:60,864,051...60,874,556
JBrowse link
G Prdx5 peroxiredoxin 5 increases expression
multiple interactions
EXP sodium nitrate results in increased expression of PRDX5 protein
sodium nitrate inhibits the reaction [Doxorubicin results in decreased expression of PRDX5 protein]
CTD PMID:21251210, PMID:22484629 NCBI chr19:6,906,697...6,910,106
Ensembl chr19:6,906,697...6,910,106
JBrowse link
G Pygb brain glycogen phosphorylase multiple interactions EXP sodium nitrate inhibits the reaction [Doxorubicin results in decreased expression of PYGB protein] CTD PMID:21251210 NCBI chr 2:150,786,796...150,831,748
Ensembl chr 2:150,786,735...150,831,758
JBrowse link
G Pygm muscle glycogen phosphorylase multiple interactions EXP sodium nitrate inhibits the reaction [Doxorubicin results in increased expression of PYGM protein] CTD PMID:21251210 NCBI chr19:6,384,408...6,398,464
Ensembl chr19:6,384,399...6,398,459
JBrowse link
G Serpina1c serine (or cysteine) peptidase inhibitor, clade A, member 1C multiple interactions EXP sodium nitrate inhibits the reaction [Doxorubicin affects the expression of SERPINA1C protein] CTD PMID:21251210 NCBI chr12:103,894,926...103,904,950
Ensembl chr12:103,894,926...103,904,887
JBrowse link
G Sod2 superoxide dismutase 2, mitochondrial multiple interactions EXP sodium nitrate inhibits the reaction [Doxorubicin results in increased expression of SOD2 protein] CTD PMID:21251210 NCBI chr17:13,007,839...13,018,119
Ensembl chr17:13,006,846...13,040,063
JBrowse link
G Srl sarcalumenin multiple interactions EXP sodium nitrate inhibits the reaction [Doxorubicin results in increased expression of SRL protein] CTD PMID:21251210 NCBI chr16:4,476,979...4,541,908
Ensembl chr16:4,480,216...4,541,816
JBrowse link
G Suclg2 succinate-Coenzyme A ligase, GDP-forming, beta subunit multiple interactions EXP sodium nitrate inhibits the reaction [Doxorubicin results in decreased expression of SUCLG2 protein] CTD PMID:21251210 NCBI chr 6:95,473,009...95,718,858
Ensembl chr 6:95,473,009...95,718,800
JBrowse link
G Uqcrc1 ubiquinol-cytochrome c reductase core protein 1 multiple interactions EXP sodium nitrate inhibits the reaction [Doxorubicin results in increased expression of UQCRC1 protein] CTD PMID:21251210 NCBI chr 9:108,936,648...108,949,641
Ensembl chr 9:108,936,633...108,949,623
JBrowse link
G Xdh xanthine dehydrogenase increases metabolic processing EXP XDH protein results in increased metabolism of sodium nitrate CTD PMID:20142047 NCBI chr17:73,883,895...73,950,397
Ensembl chr17:73,883,895...73,950,196
JBrowse link
G Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide multiple interactions EXP sodium nitrate inhibits the reaction [Doxorubicin results in decreased expression of YWHAZ protein] CTD PMID:21251210 NCBI chr15:36,770,261...36,802,984
Ensembl chr15:36,770,770...36,796,929
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 21475
    chemical entity 21474
      group 21329
        polyatomic entity 21329
          heteroatomic molecular entity 21249
            salt 15119
              nitrate salt 326
                inorganic nitrate salt + 326
                organic nitrate salt + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 21475
    subatomic particle 21460
      composite particle 21460
        hadron 21460
          baryon 21460
            nucleon 21460
              atomic nucleus 21460
                atom 21460
                  main group element atom 21361
                    p-block element atom 21361
                      chalcogen 20416
                        chalcogen molecular entity 20416
                          oxygen molecular entity 20392
                            oxide 12166
                              oxoanion 9023
                                pnictogen oxoanion 3613
                                  nitrogen oxoanion 339
                                    nitrate 326
                                      nitrate salt 326
                                        inorganic nitrate salt + 326
                                        organic nitrate salt + 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.