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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:nitrate salt
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Accession:CHEBI:51082 term browser browse the term


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ammonium nitrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL1B interleukin 1 beta increases expression EXP ammonium nitrate results in increased expression of IL1B protein CTD PMID:29953848 NCBI chr 2:112,829,751...112,836,843
Ensembl chr 2:112,829,751...112,836,816
JBrowse link
cadmium nitrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAV1 caveolin 1 decreases expression EXP cadmium nitrate results in decreased expression of CAV1 protein CTD PMID:19061949 NCBI chr 7:116,525,009...116,561,185
Ensembl chr 7:116,525,001...116,561,184
JBrowse link
G G6PD glucose-6-phosphate dehydrogenase decreases activity ISO cadmium nitrate results in decreased activity of G6PD protein CTD PMID:28557068 NCBI chr  X:154,531,390...154,547,569
Ensembl chr  X:154,531,391...154,547,572
JBrowse link
G ITGB4 integrin subunit beta 4 decreases expression EXP cadmium nitrate results in decreased expression of ITGB4 protein CTD PMID:19061949 NCBI chr17:75,721,339...75,757,819
Ensembl chr17:75,721,328...75,757,818
JBrowse link
chromium trinitrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AHSG alpha 2-HS glycoprotein decreases expression ISO chromium nitrate results in decreased expression of AHSG protein CTD PMID:23618972 NCBI chr 3:186,613,060...186,621,318
Ensembl chr 3:186,613,060...186,621,318
JBrowse link
G ALDH1L2 aldehyde dehydrogenase 1 family member L2 increases expression ISO chromium nitrate results in increased expression of ALDH1L2 protein CTD PMID:22144121 NCBI chr12:105,019,784...105,084,609
Ensembl chr12:105,019,784...105,107,643
JBrowse link
G APCS amyloid P component, serum increases expression ISO chromium nitrate results in increased expression of APCS protein CTD PMID:23618972 NCBI chr 1:159,587,826...159,588,865
Ensembl chr 1:159,587,826...159,588,865
JBrowse link
G APOA1 apolipoprotein A1 decreases expression ISO chromium nitrate results in decreased expression of APOA1 protein CTD PMID:23618972 NCBI chr11:116,835,751...116,837,950
Ensembl chr11:116,835,751...116,837,622
Ensembl chr11:116,835,751...116,837,622
JBrowse link
G ATP5F1B ATP synthase F1 subunit beta increases expression ISO chromium nitrate results in increased expression of ATP5B protein CTD PMID:19771553 NCBI chr12:56,638,175...56,645,984
Ensembl chr12:56,638,175...56,645,984
JBrowse link
G BCKDHB branched chain keto acid dehydrogenase E1 subunit beta decreases expression ISO chromium nitrate results in decreased expression of BCKDHB protein CTD PMID:22144121 NCBI chr 6:80,106,610...80,469,088
Ensembl chr 6:80,106,647...80,346,270
JBrowse link
G CCT5 chaperonin containing TCP1 subunit 5 decreases expression ISO chromium nitrate results in decreased expression of CCT5 protein CTD PMID:22144121 NCBI chr 5:10,249,921...10,266,412
Ensembl chr 5:10,249,929...10,266,389
JBrowse link
G CES1 carboxylesterase 1 increases expression ISO chromium nitrate results in increased expression of CES1D protein CTD PMID:22144121 NCBI chr16:55,802,851...55,833,127
Ensembl chr16:55,802,851...55,833,337
JBrowse link
G DBT dihydrolipoamide branched chain transacylase E2 increases expression ISO chromium nitrate results in increased expression of DBT protein CTD PMID:22144121 NCBI chr 1:100,186,919...100,249,864
Ensembl chr 1:100,186,919...100,249,834
JBrowse link
G DDAH1 dimethylarginine dimethylaminohydrolase 1 decreases expression ISO chromium nitrate results in decreased expression of DDAH1 protein CTD PMID:22144121 NCBI chr 1:85,318,485...85,578,274
Ensembl chr 1:85,318,481...85,578,363
JBrowse link
G ECH1 enoyl-CoA hydratase 1 increases expression ISO chromium nitrate results in increased expression of ECH1 protein CTD PMID:22144121 NCBI chr19:38,815,422...38,831,794
Ensembl chr19:38,815,422...38,831,841
JBrowse link
G FBP1 fructose-bisphosphatase 1 increases expression ISO chromium nitrate results in increased expression of FBP1 protein CTD PMID:22144121 NCBI chr 9:94,603,133...94,640,263
Ensembl chr 9:94,603,133...94,640,249
JBrowse link
G FGB fibrinogen beta chain increases expression ISO chromium nitrate results in increased expression of FGB protein CTD PMID:23618972 NCBI chr 4:154,562,980...154,572,807
Ensembl chr 4:154,563,011...154,572,807
Ensembl chr 4:154,563,011...154,572,807
JBrowse link
G FGG fibrinogen gamma chain increases expression ISO chromium nitrate results in increased expression of FGG protein CTD PMID:23618972 NCBI chr 4:154,604,136...154,612,656
Ensembl chr 4:154,604,134...154,612,967
JBrowse link
G FKRP fukutin related protein increases expression ISO chromium nitrate results in increased expression of FKRP protein CTD PMID:23618972 NCBI chr19:46,746,015...46,758,575
Ensembl chr19:46,746,046...46,776,988
JBrowse link
G GC GC vitamin D binding protein decreases expression ISO chromium nitrate results in decreased expression of GC protein CTD PMID:23618972 NCBI chr 4:71,741,693...71,805,520
Ensembl chr 4:71,741,696...71,804,041
JBrowse link
G GCLC glutamate-cysteine ligase catalytic subunit increases expression EXP chromium nitrate results in increased expression of GCLC mRNA CTD PMID:20491607 NCBI chr 6:53,497,341...53,545,101
Ensembl chr 6:53,497,341...53,616,970
JBrowse link
G HAAO 3-hydroxyanthranilate 3,4-dioxygenase increases expression ISO chromium nitrate results in increased expression of HAAO protein CTD PMID:22144121 NCBI chr 2:42,767,087...42,801,002
Ensembl chr 2:42,767,089...42,792,593
JBrowse link
G HACL1 2-hydroxyacyl-CoA lyase 1 increases expression ISO chromium nitrate results in increased expression of HACL1 protein CTD PMID:22144121 NCBI chr 3:15,560,699...15,601,569
Ensembl chr 3:15,560,699...15,601,852
JBrowse link
G HIBADH 3-hydroxyisobutyrate dehydrogenase increases expression ISO chromium nitrate results in increased expression of HIBADH protein CTD PMID:22144121 NCBI chr 7:27,525,440...27,662,903
Ensembl chr 7:27,525,442...27,662,883
JBrowse link
G HMOX1 heme oxygenase 1 increases expression EXP chromium nitrate results in increased expression of HMOX1 mRNA CTD PMID:20491607 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,207
JBrowse link
G HSPD1 heat shock protein family D (Hsp60) member 1 increases expression ISO chromium nitrate results in increased expression of HSPD1 protein CTD PMID:19771553 NCBI chr 2:197,486,584...197,500,274
Ensembl chr 2:197,486,584...197,516,737
JBrowse link
G KHK ketohexokinase decreases expression ISO chromium nitrate results in decreased expression of KHK protein CTD PMID:22144121 NCBI chr 2:27,086,760...27,100,762
Ensembl chr 2:27,086,747...27,100,762
JBrowse link
G KNG1 kininogen 1 increases expression ISO chromium nitrate results in increased expression of KNG1 protein CTD PMID:23618972 NCBI chr 3:186,717,359...186,744,410
Ensembl chr 3:186,717,348...186,744,410
JBrowse link
G KRT10 keratin 10 increases expression ISO chromium nitrate results in increased expression of KRT10 protein CTD PMID:19771553 NCBI chr17:40,818,117...40,822,614
Ensembl chr17:40,818,117...40,822,614
JBrowse link
G KRT16 keratin 16 increases expression ISO chromium nitrate results in increased expression of KRT16 protein CTD PMID:19771553 NCBI chr17:41,609,778...41,612,767
Ensembl chr17:41,609,778...41,615,899
JBrowse link
G KRT17 keratin 17 increases expression ISO chromium nitrate results in increased expression of KRT17 protein CTD PMID:19771553 NCBI chr17:41,619,442...41,624,575
Ensembl chr17:41,619,442...41,624,842
JBrowse link
G KRT18 keratin 18 decreases expression ISO chromium nitrate results in decreased expression of KRT18 protein CTD PMID:22144121 NCBI chr12:52,948,855...52,952,906
Ensembl chr12:52,948,871...52,952,906
JBrowse link
G KRT25 keratin 25 increases expression ISO chromium nitrate results in increased expression of KRT25 protein CTD PMID:19771553 NCBI chr17:40,748,021...40,755,542
Ensembl chr17:40,748,021...40,755,331
JBrowse link
G KRT27 keratin 27 increases expression ISO chromium nitrate results in increased expression of KRT27 protein CTD PMID:19771553 NCBI chr17:40,776,808...40,782,550
Ensembl chr17:40,776,808...40,782,550
JBrowse link
G MDH1 malate dehydrogenase 1 increases expression ISO chromium nitrate results in increased expression of MDH1 protein CTD PMID:22144121 NCBI chr 2:63,588,963...63,607,197
Ensembl chr 2:63,588,609...63,607,197
JBrowse link
G MT2A metallothionein 2A increases expression EXP chromium nitrate results in increased expression of MT2A mRNA CTD PMID:20491607 NCBI chr16:56,608,584...56,609,497
Ensembl chr16:56,608,584...56,609,497
JBrowse link
G PARK7 Parkinsonism associated deglycase increases expression ISO chromium nitrate results in increased expression of PARK7 protein CTD PMID:22144121 NCBI chr 1:7,961,711...7,985,505
Ensembl chr 1:7,954,291...7,985,505
JBrowse link
G PCCA propionyl-CoA carboxylase subunit alpha increases expression ISO chromium nitrate results in increased expression of PCCA protein CTD PMID:22144121 NCBI chr13:100,089,020...100,530,435
Ensembl chr13:100,089,015...100,530,437
JBrowse link
G PDHB pyruvate dehydrogenase E1 subunit beta decreases expression ISO chromium nitrate results in decreased expression of PDHB protein CTD PMID:22144121 NCBI chr 3:58,427,630...58,433,832
Ensembl chr 3:58,427,630...58,433,857
JBrowse link
G PHB prohibitin decreases expression ISO chromium nitrate results in decreased expression of PHB protein CTD PMID:22144121 NCBI chr17:49,404,052...49,414,882
Ensembl chr17:49,404,049...49,414,905
JBrowse link
G RGN regucalcin decreases expression ISO chromium nitrate results in decreased expression of RGN protein CTD PMID:22144121 NCBI chr  X:47,078,414...47,093,313
Ensembl chr  X:47,078,355...47,093,314
JBrowse link
G RPLP0 ribosomal protein lateral stalk subunit P0 decreases expression ISO chromium nitrate results in decreased expression of RPLP0 protein CTD PMID:22144121 NCBI chr12:120,196,699...120,201,111
Ensembl chr12:120,196,699...120,201,235
JBrowse link
G SERPINC1 serpin family C member 1 decreases expression ISO chromium nitrate results in decreased expression of SERPINC1 protein CTD PMID:23618972 NCBI chr 1:173,903,800...173,917,327
Ensembl chr 1:173,903,804...173,917,378
JBrowse link
G SUCLG2 succinate-CoA ligase GDP-forming subunit beta decreases expression ISO chromium nitrate results in decreased expression of SUCLG2 protein CTD PMID:22144121 NCBI chr 3:67,360,460...67,654,612
Ensembl chr 3:67,360,460...67,654,612
Ensembl chr 3:67,360,460...67,654,612
JBrowse link
G TKFC triokinase and FMN cyclase increases expression ISO chromium nitrate results in increased expression of TKFC protein CTD PMID:22144121 NCBI chr11:61,333,228...61,353,426
Ensembl chr11:61,333,210...61,353,295
JBrowse link
G UQCRC1 ubiquinol-cytochrome c reductase core protein 1 decreases expression ISO chromium nitrate results in decreased expression of UQCRC1 protein CTD PMID:22144121 NCBI chr 3:48,599,002...48,609,664
Ensembl chr 3:48,599,002...48,610,976
JBrowse link
G VCP valosin containing protein decreases expression ISO chromium nitrate results in decreased expression of VCP protein CTD PMID:22144121 NCBI chr 9:35,056,064...35,072,625
Ensembl chr 9:35,056,064...35,072,627
JBrowse link
copper(II) nitrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AHR aryl hydrocarbon receptor multiple interactions EXP [copper(II) nitrate binds to 1,10-phenanthroline binds to Quinolones] which results in increased activity of AHR protein; [copper(II) nitrate binds to 5-methyl-1,10-phenanthroline binds to Quinolones] which results in increased activity of AHR protein; Resveratrol inhibits the reaction [[copper(II) nitrate binds to 1,10-phenanthroline binds to Quinolones] which results in increased activity of AHR protein]; Resveratrol inhibits the reaction [[copper(II) nitrate binds to 5-methyl-1,10-phenanthroline binds to Quinolones] which results in increased activity of AHR protein] CTD PMID:27180721 NCBI chr 7:17,298,652...17,346,147
Ensembl chr 7:16,916,359...17,346,152
JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 multiple interactions EXP [copper(II) nitrate binds to 1,10-phenanthroline binds to Quinolones] which results in increased expression of CYP1A1 mRNA; [copper(II) nitrate binds to 5-methyl-1,10-phenanthroline binds to Quinolones] which results in increased expression of CYP1A1 mRNA; [copper(II) nitrate binds to bathophenanthroline binds to Quinolones] which results in increased expression of CYP1A1 mRNA CTD PMID:27180721 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536
JBrowse link
G IL2 interleukin 2 decreases secretion EXP copper(II) nitrate results in decreased secretion of IL2 protein CTD PMID:27714827 NCBI chr 4:122,451,470...122,456,725
Ensembl chr 4:122,451,470...122,456,725
JBrowse link
lead nitrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACO1 aconitase 1 decreases expression
multiple interactions
EXP lead nitrate results in decreased expression of ACO1 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [lead nitrate results in decreased expression of ACO1 protein]
CTD PMID:22502979 NCBI chr 9:32,384,643...32,454,769
Ensembl chr 9:32,384,603...32,454,769
JBrowse link
G ACTA1 actin alpha 1, skeletal muscle increases expression ISO lead nitrate results in increased expression of ACTA1 protein CTD PMID:20435106 NCBI chr 1:229,431,245...229,434,094
Ensembl chr 1:229,431,245...229,434,098
JBrowse link
G AKAP3 A-kinase anchoring protein 3 decreases expression ISO lead nitrate results in decreased expression of AKAP3 mRNA CTD PMID:21628963 NCBI chr12:4,615,514...4,649,051
Ensembl chr12:4,615,508...4,649,051
JBrowse link
G ALAD aminolevulinate dehydratase multiple interactions
decreases activity
EXP lead nitrate inhibits the reaction [Dithiothreitol results in increased activity of ALAD protein]; lead nitrate inhibits the reaction [zinc chloride promotes the reaction [Dithiothreitol results in increased activity of ALAD protein]]
lead nitrate results in decreased activity of ALAD protein
CTD PMID:2061546 NCBI chr 9:113,386,312...113,401,301
Ensembl chr 9:113,386,312...113,401,290
JBrowse link
G APAF1 apoptotic peptidase activating factor 1 decreases expression
multiple interactions
ISO lead nitrate results in decreased expression of APAF1 protein
mangiferin inhibits the reaction [lead nitrate results in decreased expression of APAF1 protein]
CTD PMID:23451106 NCBI chr12:98,645,141...98,735,433
Ensembl chr12:98,645,141...98,735,433
Ensembl chr12:98,645,141...98,735,433
JBrowse link
G ARHGDIB Rho GDP dissociation inhibitor beta increases expression ISO lead nitrate results in increased expression of ARHGDIB protein CTD PMID:20435106 NCBI chr12:14,942,015...14,961,601
Ensembl chr12:14,942,031...14,961,728
JBrowse link
G ARRDC5 arrestin domain containing 5 decreases expression ISO lead nitrate results in decreased expression of ARRDC5 mRNA CTD PMID:21628963 NCBI chr19:4,867,614...4,915,469
Ensembl chr19:4,890,437...4,902,896
JBrowse link
G AZIN2 antizyme inhibitor 2 decreases expression ISO lead nitrate results in decreased expression of AZIN2 mRNA CTD PMID:21628963 NCBI chr 1:33,081,152...33,162,288
Ensembl chr 1:33,081,104...33,123,492
JBrowse link
G BAX BCL2 associated X, apoptosis regulator multiple interactions
increases expression
ISO
EXP
mangiferin inhibits the reaction [lead nitrate results in increased expression of BAX protein]
[lead nitrate results in increased abundance of Lead] which results in increased expression of BAX mRNA; titanium dioxide inhibits the reaction [[lead nitrate results in increased abundance of Lead] which results in decreased expression of BAX mRNA]; titanium dioxide inhibits the reaction [[lead nitrate results in increased abundance of Lead] which results in increased expression of BAX mRNA]
CTD PMID:23451106, PMID:30738203 NCBI chr19:48,954,825...48,961,798
Ensembl chr19:48,954,815...48,961,798
JBrowse link
G BCL2 BCL2 apoptosis regulator decreases expression
multiple interactions
ISO
EXP
lead nitrate results in decreased expression of BCL2 protein
[lead nitrate results in increased abundance of Lead] which results in decreased expression of BCL2 mRNA
mangiferin inhibits the reaction [lead nitrate results in decreased expression of BCL2 protein]
CTD PMID:23451106, PMID:30738203 NCBI chr18:63,123,346...63,320,280
Ensembl chr18:63,123,346...63,320,128
JBrowse link
G C1orf56 chromosome 1 open reading frame 56 decreases expression ISO lead nitrate results in decreased expression of RGD1359334 mRNA CTD PMID:21628963 NCBI chr 1:151,047,751...151,051,420
Ensembl chr 1:151,047,751...151,051,986
JBrowse link
G CASP3 caspase 3 increases expression
multiple interactions
increases activity
ISO
EXP
lead nitrate results in increased expression of CASP3 protein
[lead nitrate results in increased abundance of Lead] which results in increased activity of CASP3 protein; [lead nitrate results in increased abundance of Lead] which results in increased expression of CASP3 mRNA; titanium dioxide inhibits the reaction [[lead nitrate results in increased abundance of Lead] which results in increased activity of CASP3 protein]; titanium dioxide inhibits the reaction [[lead nitrate results in increased abundance of Lead] which results in increased expression of CASP3 mRNA]
puerarin inhibits the reaction [lead nitrate results in increased activity of CASP3 protein]
mangiferin inhibits the reaction [lead nitrate results in increased expression of CASP3 protein]
CTD PMID:23451106, PMID:24505050, PMID:30738203 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,649,509
JBrowse link
G CASP7 caspase 7 multiple interactions
decreases expression
ISO lead nitrate affects the reaction [CASP7 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [CASP7 affects the expression of MT2 mRNA]
lead nitrate results in decreased expression of CASP7 mRNA
CTD PMID:11891201 NCBI chr10:113,679,194...113,730,909
Ensembl chr10:113,679,162...113,730,907
JBrowse link
G CASP9 caspase 9 multiple interactions
increases expression
ISO
EXP
mangiferin inhibits the reaction [lead nitrate results in increased expression of CASP9 protein]
[lead nitrate results in increased abundance of Lead] which results in increased activity of CASP9 protein; [lead nitrate results in increased abundance of Lead] which results in increased expression of CASP9 mRNA; titanium dioxide inhibits the reaction [[lead nitrate results in increased abundance of Lead] which results in increased activity of CASP9 protein]; titanium dioxide inhibits the reaction [[lead nitrate results in increased abundance of Lead] which results in increased expression of CASP9 mRNA]
CTD PMID:23451106, PMID:30738203 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534
JBrowse link
G CAT catalase decreases activity
multiple interactions
ISO
EXP
lead nitrate results in decreased activity of CAT protein
[lead nitrate results in increased abundance of Lead] which results in decreased activity of CAT protein; titanium dioxide inhibits the reaction [[lead nitrate results in increased abundance of Lead] which results in decreased activity of CAT protein]
Ashwagandha inhibits the reaction [lead nitrate results in decreased activity of CAT protein]; puerarin inhibits the reaction [lead nitrate results in decreased activity of CAT protein]
mangiferin inhibits the reaction [lead nitrate results in decreased activity of CAT protein]
CTD PMID:23315276, PMID:23451106, PMID:24987671, PMID:30738203 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
JBrowse link
G CCNG1 cyclin G1 multiple interactions ISO lead nitrate affects the reaction [CCNG1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [CCNG1 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr 5:163,437,571...163,448,199
Ensembl chr 5:163,437,569...163,446,151
JBrowse link
G CD86 CD86 molecule increases expression ISO lead nitrate results in increased expression of CD86 protein CTD PMID:23376802 NCBI chr 3:122,055,362...122,121,136
Ensembl chr 3:122,055,362...122,121,139
JBrowse link
G CDYL chromodomain Y like decreases expression ISO lead nitrate results in decreased expression of CDYL mRNA CTD PMID:21628963 NCBI chr 6:4,706,138...4,955,544
Ensembl chr 6:4,706,159...4,955,551
JBrowse link
G CHUK component of inhibitor of nuclear factor kappa B kinase complex increases phosphorylation
multiple interactions
ISO lead nitrate results in increased phosphorylation of CHUK protein
mangiferin inhibits the reaction [lead nitrate results in increased phosphorylation of CHUK protein]
CTD PMID:23451106 NCBI chr10:100,188,300...100,229,610
Ensembl chr10:100,188,300...100,229,596
JBrowse link
G COX8C cytochrome c oxidase subunit 8C decreases expression ISO lead nitrate results in decreased expression of COX8C mRNA CTD PMID:21628963 NCBI chr14:93,347,182...93,348,356
Ensembl chr14:93,347,182...93,348,356
JBrowse link
G CRISP2 cysteine rich secretory protein 2 decreases expression ISO lead nitrate results in decreased expression of CRISP2 mRNA CTD PMID:21628963 NCBI chr 6:49,676,665...49,714,198
Ensembl chr 6:49,692,358...49,713,590
JBrowse link
G CRYAA crystallin alpha A affects metabolic processing ISO lead nitrate affects the metabolism of CRYAA protein CTD PMID:21139692 NCBI chr21:43,169,008...43,172,810
Ensembl chr21:43,169,008...43,172,805
JBrowse link
G CRYAB crystallin alpha B affects metabolic processing ISO lead nitrate affects the metabolism of CRYAB protein CTD PMID:21139692 NCBI chr11:111,908,564...111,923,740
Ensembl chr11:111,908,564...111,923,722
JBrowse link
G CST8 cystatin 8 decreases expression ISO lead nitrate results in decreased expression of CST8 mRNA CTD PMID:21628963 NCBI chr20:23,491,077...23,507,124
Ensembl chr20:23,491,101...23,496,010
JBrowse link
G CTNNA1 catenin alpha 1 multiple interactions ISO lead nitrate affects the reaction [CTNNA1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [CTNNA1 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr 5:138,753,425...138,935,034
Ensembl chr 5:138,610,967...138,935,034
JBrowse link
G CTNNB1 catenin beta 1 multiple interactions ISO [lead nitrate results in increased abundance of Lead] which results in decreased expression of and affects the localization of CTNNB1 protein; [lead nitrate results in increased abundance of Lead] which results in decreased expression of CTNNB1 mRNA; icaritin inhibits the reaction [[lead nitrate results in increased abundance of Lead] which results in decreased expression of and affects the localization of CTNNB1 protein]; icaritin inhibits the reaction [[lead nitrate results in increased abundance of Lead] which results in decreased expression of CTNNB1 mRNA] CTD PMID:30731080 NCBI chr 3:41,199,422...41,240,445
Ensembl chr 3:41,194,741...41,260,096
JBrowse link
G CUX2 cut like homeobox 2 multiple interactions ISO lead nitrate affects the reaction [CUX2 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [CUX2 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr12:111,034,165...111,350,556
Ensembl chr12:111,034,165...111,350,554
JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 multiple interactions
increases expression
EXP
ISO
lead nitrate inhibits the reaction [1,2,5,6-dibenzanthracene results in increased activity of CYP1A1 protein]; lead nitrate inhibits the reaction [benz(a)anthracene results in increased activity of CYP1A1 protein]; lead nitrate inhibits the reaction [Benzo(a)pyrene results in increased activity of CYP1A1 protein]; lead nitrate inhibits the reaction [benzo(b)fluoranthene results in increased activity of CYP1A1 protein]; lead nitrate inhibits the reaction [benzo(k)fluoranthene results in increased activity of CYP1A1 protein]; lead nitrate inhibits the reaction [benzo(k)fluoranthene results in increased expression of CYP1A1 protein]; lead nitrate inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of CYP1A1 protein]; lead nitrate promotes the reaction [benzo(k)fluoranthene results in increased expression of CYP1A1 protein]
lead nitrate inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CYP1A1 protein]; lead nitrate inhibits the reaction [2-amino-3-methyl-9H-pyrido(2,3-b)indole results in increased expression of CYP1A1 mRNA]; lead nitrate inhibits the reaction [2-amino-3-methyl-9H-pyrido(2,3-b)indole results in increased expression of CYP1A1 protein]; lead nitrate inhibits the reaction [2-methoxy-4-aminoazobenzene results in increased expression of CYP1A1 protein]; lead nitrate inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 protein]; lead nitrate inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 protein]; lead nitrate inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 protein]; resveratrol inhibits the reaction [lead nitrate results in increased expression of CYP1A1 mRNA]
lead nitrate results in increased expression of CYP1A1 mRNA; lead nitrate results in increased expression of CYP1A1 protein
CTD PMID:8902619, PMID:11162773, PMID:11408366, PMID:17889500, PMID:23391631 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536
JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 decreases activity
multiple interactions
EXP
ISO
lead nitrate results in decreased activity of CYP1A2 protein
lead nitrate inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CYP1A2 mRNA]; lead nitrate inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CYP1A2 protein]; lead nitrate inhibits the reaction [2-amino-3-methyl-9H-pyrido(2,3-b)indole results in increased expression of CYP1A2 mRNA]; lead nitrate inhibits the reaction [2-amino-3-methyl-9H-pyrido(2,3-b)indole results in increased expression of CYP1A2 protein]; lead nitrate inhibits the reaction [2-methoxy-4-aminoazobenzene results in increased expression of CYP1A2 mRNA]; lead nitrate inhibits the reaction [2-methoxy-4-aminoazobenzene results in increased expression of CYP1A2 protein]; lead nitrate inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 protein]; lead nitrate inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A2 protein]; lead nitrate inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A2 protein]; lead nitrate results in decreased expression of and results in decreased activity of CYP1A2 protein
CTD PMID:8902619, PMID:11162773 NCBI chr15:74,748,845...74,756,607
Ensembl chr15:74,748,845...74,756,607
JBrowse link
G CYP4A22 cytochrome P450 family 4 subfamily A member 22 increases expression ISO lead nitrate results in increased expression of CYP4A1 mRNA CTD PMID:23391631 NCBI chr 1:47,137,441...47,149,738
Ensembl chr 1:47,137,435...47,149,735
JBrowse link
G CYP51A1 cytochrome P450 family 51 subfamily A member 1 increases expression
multiple interactions
ISO lead nitrate results in increased expression of CYP51 mRNA
[IL1A gene mutant form co-treated with IL1B gene mutant form] inhibits the reaction [lead nitrate results in increased expression of CYP51 mRNA]
CTD PMID:15475176, PMID:22293356 NCBI chr 7:92,112,153...92,134,803
Ensembl chr 7:92,112,153...92,134,803
JBrowse link
G CYP7A1 cytochrome P450 family 7 subfamily A member 1 decreases expression
multiple interactions
ISO lead nitrate results in decreased expression of CYP7A1 mRNA
[IL1A gene mutant form co-treated with IL1B gene mutant form] inhibits the reaction [lead nitrate results in decreased expression of CYP7A1 mRNA]
CTD PMID:15475176, PMID:16049268, PMID:22293356 NCBI chr 8:58,490,178...58,500,163
Ensembl chr 8:58,490,178...58,500,163
JBrowse link
G DDIT3 DNA damage inducible transcript 3 increases expression EXP lead nitrate results in increased expression of DDIT3 mRNA CTD PMID:14971657 NCBI chr12:57,516,588...57,520,517
Ensembl chr12:57,516,588...57,521,737
JBrowse link
G DKK1 dickkopf WNT signaling pathway inhibitor 1 multiple interactions ISO [lead nitrate results in increased abundance of Lead] which results in increased expression of DKK1 mRNA; [lead nitrate results in increased abundance of Lead] which results in increased expression of DKK1 protein; icaritin inhibits the reaction [[lead nitrate results in increased abundance of Lead] which results in increased expression of DKK1 mRNA]; icaritin inhibits the reaction [[lead nitrate results in increased abundance of Lead] which results in increased expression of DKK1 protein] CTD PMID:30731080 NCBI chr10:52,314,281...52,317,657
Ensembl chr10:52,314,281...52,318,042
JBrowse link
G DNASE1 deoxyribonuclease 1 multiple interactions ISO lead nitrate affects the reaction [DNASE1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [DNASE1 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr16:3,611,737...3,665,472
Ensembl chr16:3,611,728...3,680,143
JBrowse link
G DNMT3A DNA methyltransferase 3 alpha multiple interactions
decreases expression
EXP 4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline inhibits the reaction [lead nitrate results in decreased expression of DNMT3A mRNA]; E2F1 protein inhibits the reaction [lead nitrate results in decreased expression of DNMT3A mRNA]; RTKI cpd inhibits the reaction [lead nitrate results in decreased expression of DNMT3A mRNA]
lead nitrate results in decreased expression of DNMT3A mRNA; lead nitrate results in decreased expression of DNMT3A protein
CTD PMID:24639330 NCBI chr 2:25,227,874...25,342,590
Ensembl chr 2:25,227,855...25,342,590
JBrowse link
G E2F1 E2F transcription factor 1 multiple interactions EXP E2F1 protein inhibits the reaction [lead nitrate results in decreased expression of DNMT3A mRNA]; E2F1 protein inhibits the reaction [lead nitrate results in increased expression of PTGS2 mRNA]; lead nitrate inhibits the reaction [E2F1 protein results in decreased expression of PTGS2 mRNA] CTD PMID:24639330 NCBI chr20:33,675,477...33,686,385
Ensembl chr20:33,675,477...33,686,385
JBrowse link
G EGFL8 EGF like domain multiple 8 increases expression ISO lead nitrate results in increased expression of EGFL8 protein CTD PMID:19332663 NCBI chr 6:32,164,595...32,168,281
Ensembl chr 6:32,164,595...32,168,281
JBrowse link
G EGFR epidermal growth factor receptor multiple interactions
increases phosphorylation
EXP EGFR mutant form affects the reaction [[lead nitrate results in increased expression of PLA2G4A mRNA] which results in increased secretion of Dinoprostone]; EGFR mutant form affects the reaction [lead nitrate results in increased expression of PLA2G4A mRNA]; EGFR mutant form affects the reaction [lead nitrate results in increased secretion of Dinoprostone]; EGFR promotes the reaction [lead nitrate results in increased expression of PLA2G4A mRNA]; RTKI cpd inhibits the reaction [lead nitrate results in increased phosphorylation of EGFR protein] CTD PMID:20850495 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628
JBrowse link
G EIF2AK1 eukaryotic translation initiation factor 2 alpha kinase 1 increases response to substance
multiple interactions
ISO EIF2AK1 gene mutant form results in increased susceptibility to lead nitrate
[lead nitrate co-treated with EIF2AK1 gene mutant form] results in increased abundance of Bilirubin; [lead nitrate co-treated with EIF2AK1 gene mutant form] results in increased abundance of Malondialdehyde; [lead nitrate co-treated with EIF2AK1 gene mutant form] results in increased expression of HAMP mRNA
CTD PMID:25411909 NCBI chr 7:6,022,247...6,059,175
Ensembl chr 7:6,022,247...6,059,175
JBrowse link
G EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 increases phosphorylation
multiple interactions
ISO lead nitrate results in increased phosphorylation of EIF4EBP1 protein
puerarin inhibits the reaction [lead nitrate results in increased phosphorylation of EIF4EBP1 protein]
CTD PMID:27762461 NCBI chr 8:38,030,534...38,060,365
Ensembl chr 8:38,030,534...38,060,365
JBrowse link
G ERCC1 ERCC excision repair 1, endonuclease non-catalytic subunit multiple interactions ISO lead nitrate affects the reaction [ERCC1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [ERCC1 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr19:45,407,334...45,451,547
Ensembl chr19:45,407,333...45,478,828
Ensembl chr19:45,407,333...45,478,828
JBrowse link
G ERCC3 ERCC excision repair 3, TFIIH core complex helicase subunit multiple interactions ISO lead nitrate affects the reaction [ERCC3 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [ERCC3 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr 2:127,257,290...127,294,166
Ensembl chr 2:127,257,290...127,294,166
Ensembl chr 2:127,257,290...127,294,166
JBrowse link
G EZR ezrin multiple interactions ISO lead nitrate affects the reaction [EZR affects the expression of MT1 mRNA]; lead nitrate affects the reaction [EZR affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr 6:158,765,744...158,819,368
Ensembl chr 6:158,765,741...158,819,368
JBrowse link
G FABP9 fatty acid binding protein 9 decreases expression ISO lead nitrate results in decreased expression of FABP9 mRNA CTD PMID:21628963 NCBI chr 8:81,458,253...81,461,579
Ensembl chr 8:81,458,253...81,461,579
Ensembl chr 8:81,458,253...81,461,579
JBrowse link
G FAM71F1 family with sequence similarity 71 member F1 decreases expression ISO lead nitrate results in decreased expression of FAM71F1 mRNA CTD PMID:21628963 NCBI chr 7:128,709,061...128,731,741
Ensembl chr 7:128,709,061...128,731,743
JBrowse link
G FDFT1 farnesyl-diphosphate farnesyltransferase 1 increases expression ISO lead nitrate results in increased expression of FDFT1 mRNA CTD PMID:15475176 NCBI chr 8:11,795,582...11,839,309
Ensembl chr 8:11,795,573...11,839,304
JBrowse link
G FDPS farnesyl diphosphate synthase increases expression ISO lead nitrate results in increased expression of FDPS mRNA CTD PMID:15475176 NCBI chr 1:155,308,801...155,320,665
Ensembl chr 1:155,308,748...155,320,666
JBrowse link
G FHL1 four and a half LIM domains 1 decreases expression ISO lead nitrate results in decreased expression of FHL1 mRNA CTD PMID:21628963 NCBI chr  X:136,146,702...136,211,359
Ensembl chr  X:136,146,702...136,211,359
JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit increases expression EXP lead nitrate results in increased expression of FOS mRNA CTD PMID:14971657 NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,282,230
JBrowse link
G FOXA2 forkhead box A2 multiple interactions ISO lead nitrate affects the reaction [FOXA2 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [FOXA2 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr20:22,580,998...22,585,490
Ensembl chr20:22,581,005...22,585,455
JBrowse link
G FTL ferritin light chain increases expression ISO lead nitrate results in increased expression of FTL protein CTD PMID:19332663 NCBI chr19:48,963,941...48,966,879
Ensembl chr19:48,965,309...48,966,879
JBrowse link
G G6PD glucose-6-phosphate dehydrogenase decreases activity ISO lead nitrate results in decreased activity of G6PD protein CTD PMID:28557068 NCBI chr  X:154,531,390...154,547,569
Ensembl chr  X:154,531,391...154,547,572
JBrowse link
G GADD45A growth arrest and DNA damage inducible alpha increases expression EXP lead nitrate results in increased expression of GADD45A mRNA CTD PMID:14971657 NCBI chr 1:67,685,201...67,688,334
Ensembl chr 1:67,685,201...67,688,334
JBrowse link
G GFAP glial fibrillary acidic protein multiple interactions
increases expression
ISO Ashwagandha inhibits the reaction [lead nitrate results in increased expression of GFAP mRNA]; Ashwagandha inhibits the reaction [lead nitrate results in increased expression of GFAP protein]
lead nitrate results in increased expression of GFAP mRNA; lead nitrate results in increased expression of GFAP protein
CTD PMID:24987671 NCBI chr17:44,903,159...44,915,552
Ensembl chr17:44,903,159...44,916,937
JBrowse link
G GGNBP1 gametogenetin binding protein 1 (pseudogene) decreases expression ISO lead nitrate results in decreased expression of GGNBP1 mRNA CTD PMID:21628963 NCBI chr 6:33,583,699...33,589,026
Ensembl chr 6:33,540,046...33,589,026
JBrowse link
G GH1 growth hormone 1 multiple interactions
decreases secretion
ISO lead nitrate inhibits the reaction [GHRH protein results in increased expression of GH1 protein]
lead nitrate results in decreased secretion of GH1 protein
CTD PMID:12022635 NCBI chr17:63,917,203...63,918,839
Ensembl chr17:63,917,200...63,918,839
JBrowse link
G GHRH growth hormone releasing hormone multiple interactions ISO lead nitrate inhibits the reaction [GHRH protein results in increased expression of GH1 protein] CTD PMID:12022635 NCBI chr20:37,251,086...37,261,814
Ensembl chr20:37,251,082...37,261,835
JBrowse link
G GJA5 gap junction protein alpha 5 multiple interactions
increases expression
ISO lead nitrate affects the reaction [GJA5 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [GJA5 affects the expression of MT2 mRNA]
lead nitrate results in increased expression of GJA5 mRNA
CTD PMID:11891201 NCBI chr 1:147,756,199...147,781,127
Ensembl chr 1:147,756,199...147,773,362
JBrowse link
G GJB2 gap junction protein beta 2 multiple interactions ISO lead nitrate affects the reaction [GJB2 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [GJB2 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr13:20,187,470...20,192,938
Ensembl chr13:20,187,463...20,192,938
JBrowse link
G GRIN2A glutamate ionotropic receptor NMDA type subunit 2A multiple interactions ISO lead nitrate affects the reaction [GRIN2A affects the expression of MT1 mRNA]; lead nitrate affects the reaction [GRIN2A affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr16:9,753,404...10,182,928
Ensembl chr16:9,753,404...10,182,928
Ensembl chr16:9,753,404...10,182,928
JBrowse link
G GRIN2C glutamate ionotropic receptor NMDA type subunit 2C increases expression ISO lead nitrate results in increased expression of GRIN2C mRNA CTD PMID:23358146 NCBI chr17:74,842,021...74,860,843
Ensembl chr17:74,842,023...74,861,504
JBrowse link
G GSG1 germ cell associated 1 decreases expression ISO lead nitrate results in decreased expression of GSG1 mRNA CTD PMID:21628963 NCBI chr12:13,083,532...13,103,678
Ensembl chr12:13,083,532...13,103,683
JBrowse link
G GSK3B glycogen synthase kinase 3 beta multiple interactions ISO [lead nitrate results in increased abundance of Lead] which results in decreased phosphorylation of GSK3B protein; icaritin inhibits the reaction [[lead nitrate results in increased abundance of Lead] which results in decreased phosphorylation of GSK3B protein] CTD PMID:30731080 NCBI chr 3:119,821,321...120,095,823
Ensembl chr 3:119,821,323...120,094,417
Ensembl chr 3:119,821,323...120,094,417
JBrowse link
G GSR glutathione-disulfide reductase multiple interactions
decreases activity
ISO mangiferin inhibits the reaction [lead nitrate results in decreased activity of GSR protein] CTD PMID:23451106 NCBI chr 8:30,678,066...30,727,846
Ensembl chr 8:30,678,066...30,727,846
JBrowse link
G GSTT1 glutathione S-transferase theta 1 multiple interactions ISO lead nitrate affects the reaction [GSTT1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [GSTT1 affects the expression of MT2 mRNA] CTD PMID:11891201
G HAMP hepcidin antimicrobial peptide multiple interactions ISO [lead nitrate co-treated with EIF2AK1 gene mutant form] results in increased expression of HAMP mRNA CTD PMID:25411909 NCBI chr19:35,282,528...35,285,143
Ensembl chr19:35,280,716...35,285,143
JBrowse link
G HMGB4 high mobility group box 4 decreases expression ISO lead nitrate results in decreased expression of HMGB4 mRNA CTD PMID:21628963 NCBI chr 1:33,860,475...33,864,791
Ensembl chr 1:33,860,475...33,864,791
JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase increases expression
multiple interactions
ISO lead nitrate results in increased expression of HMGCR mRNA
[IL1A gene mutant form co-treated with IL1B gene mutant form] inhibits the reaction [lead nitrate results in increased expression of HMGCR mRNA]
CTD PMID:15475176, PMID:16705668, PMID:22293356 NCBI chr 5:75,336,334...75,362,116
Ensembl chr 5:75,336,329...75,362,101
JBrowse link
G HMOX1 heme oxygenase 1 increases expression ISO lead nitrate results in increased expression of HMOX1 mRNA CTD PMID:23391631 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,207
JBrowse link
G HNF4A hepatocyte nuclear factor 4 alpha decreases expression ISO lead nitrate results in decreased expression of HNF4A mRNA CTD PMID:16049268 NCBI chr20:44,355,699...44,434,596
Ensembl chr20:44,355,700...44,434,596
JBrowse link
G HSP90AB1 heat shock protein 90 alpha family class B member 1 multiple interactions ISO lead nitrate affects the reaction [HSP90AB1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [HSP90AB1 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr 6:44,246,194...44,253,883
Ensembl chr 6:44,246,166...44,253,888
JBrowse link
G HSPA2 heat shock protein family A (Hsp70) member 2 multiple interactions
decreases expression
increases expression
ISO Ashwagandha inhibits the reaction [lead nitrate results in increased expression of HSPA2 mRNA]
lead nitrate results in decreased expression of HSPA2 mRNA
CTD PMID:21628963, PMID:24987671 NCBI chr14:64,540,741...64,543,237
Ensembl chr14:64,535,905...64,546,173
JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 increases expression ISO
EXP
lead nitrate results in increased expression of HSPA5 protein
lead nitrate results in increased expression of HSPA5 mRNA
CTD PMID:14971657, PMID:20435106 NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,343
JBrowse link
G HSPA9 heat shock protein family A (Hsp70) member 9 multiple interactions
increases expression
ISO Ashwagandha inhibits the reaction [lead nitrate results in increased expression of HSPA9 mRNA]; Ashwagandha inhibits the reaction [lead nitrate results in increased expression of HSPA9 protein]
lead nitrate results in increased expression of HSPA9 mRNA; lead nitrate results in increased expression of HSPA9 protein
CTD PMID:24987671 NCBI chr 5:138,553,756...138,575,401
Ensembl chr 5:138,553,756...138,575,416
JBrowse link
G IGF2 insulin like growth factor 2 multiple interactions ISO lead nitrate affects the reaction [IGF2 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [IGF2 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr11:2,129,112...2,149,603
Ensembl chr11:2,129,112...2,141,238
JBrowse link
G IGFBP6 insulin like growth factor binding protein 6 multiple interactions ISO lead nitrate affects the reaction [IGFBP6 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [IGFBP6 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr12:53,097,667...53,102,340
Ensembl chr12:53,097,436...53,102,345
JBrowse link
G IL1A interleukin 1 alpha multiple interactions
increases expression
ISO [IL1A gene mutant form co-treated with IL1B gene mutant form] inhibits the reaction [lead nitrate results in decreased expression of CYP7A1 mRNA]; [IL1A gene mutant form co-treated with IL1B gene mutant form] inhibits the reaction [lead nitrate results in increased expression of CYP51 mRNA]; [IL1A gene mutant form co-treated with IL1B gene mutant form] inhibits the reaction [lead nitrate results in increased expression of HMGCR mRNA]; [IL1A gene mutant form co-treated with IL1B gene mutant form] inhibits the reaction [lead nitrate results in increased expression of TNF mRNA]; [IL1A gene mutant form co-treated with IL1B gene mutant form] results in decreased susceptibility to lead nitrate
lead nitrate results in increased expression of IL1A mRNA
CTD PMID:22293356 NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493
JBrowse link
G IL1B interleukin 1 beta multiple interactions
increases expression
ISO [IL1A gene mutant form co-treated with IL1B gene mutant form] inhibits the reaction [lead nitrate results in decreased expression of CYP7A1 mRNA]; [IL1A gene mutant form co-treated with IL1B gene mutant form] inhibits the reaction [lead nitrate results in increased expression of CYP51 mRNA]; [IL1A gene mutant form co-treated with IL1B gene mutant form] inhibits the reaction [lead nitrate results in increased expression of HMGCR mRNA]; [IL1A gene mutant form co-treated with IL1B gene mutant form] inhibits the reaction [lead nitrate results in increased expression of TNF mRNA]; [IL1A gene mutant form co-treated with IL1B gene mutant form] results in decreased susceptibility to lead nitrate
lead nitrate results in increased expression of IL1B mRNA
lead nitrate results in increased expression of IL1B mRNA; lead nitrate results in increased expression of IL1B protein
CTD PMID:15475176, PMID:16049268, PMID:22293356 NCBI chr 2:112,829,751...112,836,843
Ensembl chr 2:112,829,751...112,836,816
JBrowse link
G IL2 interleukin 2 decreases secretion EXP lead nitrate results in decreased secretion of IL2 protein CTD PMID:27714827 NCBI chr 4:122,451,470...122,456,725
Ensembl chr 4:122,451,470...122,456,725
JBrowse link
G IL6R interleukin 6 receptor multiple interactions ISO lead nitrate affects the reaction [IL6RA affects the expression of MT1 mRNA]; lead nitrate affects the reaction [IL6RA affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr 1:154,405,343...154,469,450
Ensembl chr 1:154,405,193...154,469,450
JBrowse link
G IQCF1 IQ motif containing F1 decreases expression ISO lead nitrate results in decreased expression of IQCF1 mRNA CTD PMID:21628963 NCBI chr 3:51,894,876...51,903,353
Ensembl chr 3:51,894,876...51,903,353
JBrowse link
G IQCF5 IQ motif containing F5 decreases expression ISO lead nitrate results in decreased expression of IQCF5 mRNA CTD PMID:21628963 NCBI chr 3:51,873,721...51,875,601
Ensembl chr 3:51,873,721...51,875,601
JBrowse link
G ITGA6 integrin subunit alpha 6 multiple interactions ISO lead nitrate affects the reaction [ITGA6 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [ITGA6 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr 2:172,427,336...172,506,459
Ensembl chr 2:172,427,354...172,506,459
JBrowse link
G ITGAM integrin subunit alpha M multiple interactions ISO lead nitrate affects the reaction [ITGAM affects the expression of MT1 mRNA]; lead nitrate affects the reaction [ITGAM affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr16:31,259,975...31,332,877
Ensembl chr16:31,259,967...31,332,892
JBrowse link
G KRT14 keratin 14 increases expression ISO lead nitrate results in increased expression of KRT14 protein CTD PMID:20435106 NCBI chr17:41,582,279...41,586,895
Ensembl chr17:41,582,279...41,586,895
JBrowse link
G LAMP1 lysosomal associated membrane protein 1 increases expression ISO lead nitrate results in increased expression of LAMP1 protein CTD PMID:23376802 NCBI chr13:113,297,239...113,323,672
Ensembl chr13:113,297,239...113,323,672
JBrowse link
G LAMP2 lysosomal associated membrane protein 2 increases expression ISO lead nitrate results in increased expression of LAMP2 protein CTD PMID:23376802 NCBI chr  X:120,426,148...120,469,349
Ensembl chr  X:120,426,148...120,469,365
Ensembl chr  X:120,426,148...120,469,365
JBrowse link
G LDHC lactate dehydrogenase C decreases expression ISO lead nitrate results in decreased expression of LDHC mRNA CTD PMID:21628963 NCBI chr11:18,412,298...18,452,063
Ensembl chr11:18,412,318...18,452,063
JBrowse link
G LRRC46 leucine rich repeat containing 46 decreases expression ISO lead nitrate results in decreased expression of LRRC46 mRNA CTD PMID:21628963 NCBI chr17:47,831,670...47,837,719
Ensembl chr17:47,831,634...47,837,719
JBrowse link
G LTA lymphotoxin alpha multiple interactions ISO lead nitrate affects the reaction [LTA affects the expression of MT1 mRNA]; lead nitrate affects the reaction [LTA affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr 6:31,560,550...31,574,324
Ensembl chr 6:31,572,054...31,574,324
JBrowse link
G LYPD4 LY6/PLAUR domain containing 4 decreases expression ISO lead nitrate results in decreased expression of LYPD4 mRNA CTD PMID:21628963 NCBI chr19:41,833,686...41,845,204
Ensembl chr19:41,837,074...41,844,697
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 multiple interactions
increases phosphorylation
EXP
ISO
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [lead nitrate results in increased phosphorylation of MAPK1 protein]; 4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline inhibits the reaction [lead nitrate results in increased phosphorylation of MAPK1 protein]; RTKI cpd inhibits the reaction [lead nitrate results in increased phosphorylation of MAPK1 protein]
mangiferin inhibits the reaction [lead nitrate results in increased phosphorylation of MAPK1 protein]
CTD PMID:20850495, PMID:22502979, PMID:23451106 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,754,500...21,867,680
Ensembl chr22:21,754,500...21,867,680
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions
increases phosphorylation
EXP
ISO
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [lead nitrate results in increased phosphorylation of MAPK3 protein]; 4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline inhibits the reaction [lead nitrate results in increased phosphorylation of MAPK3 protein]; RTKI cpd inhibits the reaction [lead nitrate results in increased phosphorylation of MAPK3 protein]
mangiferin inhibits the reaction [lead nitrate results in increased phosphorylation of MAPK3 protein]
CTD PMID:20850495, PMID:22502979, PMID:23451106 NCBI chr16:30,114,105...30,123,309
Ensembl chr16:30,114,105...30,123,506
JBrowse link
G MARCHF11 membrane associated ring-CH-type finger 11 decreases expression ISO lead nitrate results in decreased expression of MARCHF11 mRNA CTD PMID:21628963 NCBI chr 5:16,067,139...16,179,791
Ensembl chr 5:16,067,139...16,180,762
JBrowse link
G MCL1 MCL1 apoptosis regulator, BCL2 family member multiple interactions ISO lead nitrate affects the reaction [MCL1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [MCL1 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr 1:150,574,558...150,579,610
Ensembl chr 1:150,574,551...150,579,738
JBrowse link
G MET MET proto-oncogene, receptor tyrosine kinase multiple interactions ISO lead nitrate affects the reaction [MET affects the expression of MT1 mRNA]; lead nitrate affects the reaction [MET affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr 7:116,672,196...116,798,386
Ensembl chr 7:116,672,196...116,798,386
JBrowse link
G MGST1 microsomal glutathione S-transferase 1 multiple interactions ISO lead nitrate affects the reaction [MGST1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [MGST1 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr12:16,347,115...16,377,192
Ensembl chr12:16,347,142...16,609,259
JBrowse link
G MROH2B maestro heat like repeat family member 2B decreases expression ISO lead nitrate results in decreased expression of MROH2B mRNA CTD PMID:21628963 NCBI chr 5:40,998,020...41,071,342
Ensembl chr 5:40,998,017...41,071,342
JBrowse link
G MT-CO1 mitochondrially encoded cytochrome c oxidase I multiple interactions
decreases expression
ISO puerarin inhibits the reaction [lead nitrate results in decreased expression of COX1 mRNA] CTD PMID:23315276 NCBI chr MT:5,904...7,445
Ensembl chr MT:5,904...7,445
JBrowse link
G MT-CO2 mitochondrially encoded cytochrome c oxidase II multiple interactions
decreases expression
ISO puerarin inhibits the reaction [lead nitrate results in decreased expression of COX2 mRNA] CTD PMID:23315276 NCBI chr MT:7,586...8,269
Ensembl chr MT:7,586...8,269
JBrowse link
G MT-CO3 mitochondrially encoded cytochrome c oxidase III multiple interactions
decreases expression
ISO puerarin inhibits the reaction [lead nitrate results in decreased expression of COX3 mRNA] CTD PMID:23315276 NCBI chr MT:9,207...9,990
Ensembl chr MT:9,207...9,990
JBrowse link
G MT1X metallothionein 1X increases expression
multiple interactions
decreases response to substance
affects localization
ISO lead nitrate results in increased expression of MT1 mRNA
lead nitrate affects the reaction [CASP7 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [CCNG1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [CTNNA1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [CUX2 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [DNASE1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [ERCC1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [ERCC3 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [EZR affects the expression of MT1 mRNA]; lead nitrate affects the reaction [FOXA2 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [GJA5 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [GJB2 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [GRIN2A affects the expression of MT1 mRNA]; lead nitrate affects the reaction [GSTT1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [HSP90AB1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [IGF2 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [IGFBP6 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [IL6RA affects the expression of MT1 mRNA]; lead nitrate affects the reaction [ITGA6 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [ITGAM affects the expression of MT1 mRNA]; lead nitrate affects the reaction [LTA affects the expression of MT1 mRNA]; lead nitrate affects the reaction [MCL1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [MET affects the expression of MT1 mRNA]; lead nitrate affects the reaction [MGST1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [MYC affects the expression of MT1 mRNA]; lead nitrate affects the reaction [NFKBIB affects the expression of MT1 mRNA]; lead nitrate affects the reaction [NUMB affects the expression of MT1 mRNA]; lead nitrate affects the reaction [PIAS2 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [POLD1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [POU3F3 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [RAD23 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [RBL2 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [RUNX1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [SERPINA1B affects the expression of MT1 mRNA]; lead nitrate affects the reaction [SOCS1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [SP3 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [SQSTM1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [SUMO1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [TBX2 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [TNFRSF1A affects the expression of MT1 mRNA]; lead nitrate affects the reaction [TNFRSF1B affects the expression of MT1 mRNA]; lead nitrate affects the reaction [TRIM27 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [TSG101 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [TTF1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [WNT4 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [ZFHX3 affects the expression of MT1 mRNA]; MT1 protein promotes the reaction [lead nitrate results in increased expression of SNCA mRNA]
MT1 results in decreased susceptibility to lead nitrate
lead nitrate affects the localization of MT1 protein
CTD PMID:11891201, PMID:19542206 NCBI chr16:56,682,470...56,684,196
Ensembl chr16:56,682,470...56,684,196
JBrowse link
G MT2A metallothionein 2A multiple interactions
decreases response to substance
ISO lead nitrate affects the reaction [CASP7 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [CCNG1 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [CTNNA1 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [CUX2 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [DNASE1 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [ERCC1 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [ERCC3 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [EZR affects the expression of MT2 mRNA]; lead nitrate affects the reaction [FOXA2 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [GJA5 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [GJB2 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [GRIN2A affects the expression of MT2 mRNA]; lead nitrate affects the reaction [GSTT1 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [HSP90AB1 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [IGF2 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [IGFBP6 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [IL6RA affects the expression of MT2 mRNA]; lead nitrate affects the reaction [ITGA6 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [ITGAM affects the expression of MT2 mRNA]; lead nitrate affects the reaction [LTA affects the expression of MT2 mRNA]; lead nitrate affects the reaction [MCL1 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [MET affects the expression of MT2 mRNA]; lead nitrate affects the reaction [MGST1 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [MYC affects the expression of MT2 mRNA]; lead nitrate affects the reaction [NFKBIB affects the expression of MT2 mRNA]; lead nitrate affects the reaction [NUMB affects the expression of MT2 mRNA]; lead nitrate affects the reaction [PIAS2 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [POLD1 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [POU3F3 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [RAD23 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [RBL2 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [RUNX1 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [SERPINA1B affects the expression of MT2 mRNA]; lead nitrate affects the reaction [SOCS1 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [SP3 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [SQSTM1 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [SUMO1 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [TBX2 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [TNFRSF1A affects the expression of MT2 mRNA]; lead nitrate affects the reaction [TNFRSF1B affects the expression of MT2 mRNA]; lead nitrate affects the reaction [TRIM27 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [TSG101 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [TTF1 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [WNT4 affects the expression of MT2 mRNA]; lead nitrate affects the reaction [ZFHX3 affects the expression of MT2 mRNA]
MT2 results in decreased susceptibility to lead nitrate
CTD PMID:11891201 NCBI chr16:56,608,584...56,609,497
Ensembl chr16:56,608,584...56,609,497
JBrowse link
G MTOR mechanistic target of rapamycin kinase increases phosphorylation
multiple interactions
ISO lead nitrate results in increased phosphorylation of MTOR protein
puerarin inhibits the reaction [lead nitrate results in increased phosphorylation of MTOR protein]
CTD PMID:27762461 NCBI chr 1:11,106,535...11,273,497
Ensembl chr 1:11,106,535...11,262,551
JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor multiple interactions ISO lead nitrate affects the reaction [MYC affects the expression of MT1 mRNA]; lead nitrate affects the reaction [MYC affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951
JBrowse link
G MYH6 myosin heavy chain 6 decreases expression ISO lead nitrate results in decreased expression of MYH6 protein CTD PMID:23391631 NCBI chr14:23,381,987...23,408,273
Ensembl chr14:23,381,982...23,408,273
JBrowse link
G MYH7 myosin heavy chain 7 increases expression
multiple interactions
ISO lead nitrate results in increased expression of MYH7 mRNA; lead nitrate results in increased expression of MYH7 protein
resveratrol inhibits the reaction [lead nitrate results in increased expression of MYH7 mRNA]
CTD PMID:23391631 NCBI chr14:23,412,740...23,435,677
Ensembl chr14:23,412,740...23,435,660
JBrowse link
G NCAM1 neural cell adhesion molecule 1 multiple interactions
decreases expression
ISO Ashwagandha inhibits the reaction [lead nitrate results in decreased expression of NCAM1 mRNA]; Ashwagandha inhibits the reaction [lead nitrate results in decreased expression of NCAM1 protein]
lead nitrate results in decreased expression of NCAM1 mRNA; lead nitrate results in decreased expression of NCAM1 protein
CTD PMID:24987671 NCBI chr11:112,961,420...113,278,436
Ensembl chr11:112,961,247...113,278,436
JBrowse link
G NFKBIA NFKB inhibitor alpha decreases expression
multiple interactions
ISO lead nitrate results in decreased expression of NFKBIA protein
mangiferin inhibits the reaction [lead nitrate results in decreased expression of NFKBIA protein]
CTD PMID:23451106 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,511...35,404,749
Ensembl chr14:35,401,511...35,404,749
JBrowse link
G NFKBIB NFKB inhibitor beta multiple interactions ISO lead nitrate affects the reaction [NFKBIB affects the expression of MT1 mRNA]; lead nitrate affects the reaction [NFKBIB affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr19:38,899,503...38,908,894
Ensembl chr19:38,899,700...38,908,893
JBrowse link
G NPPB natriuretic peptide B increases expression ISO lead nitrate results in increased expression of NPPB mRNA CTD PMID:23391631 NCBI chr 1:11,857,464...11,858,945
Ensembl chr 1:11,857,464...11,858,945
JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 increases expression ISO lead nitrate results in increased expression of NQO1 mRNA CTD PMID:23391631 NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668
JBrowse link
G NR0B2 nuclear receptor subfamily 0 group B member 2 decreases expression ISO lead nitrate results in decreased expression of NR0B2 mRNA CTD PMID:15475176, PMID:16049268 NCBI chr 1:26,911,489...26,914,110
Ensembl chr 1:26,911,489...26,913,975
JBrowse link
G NR1H3 nuclear receptor subfamily 1 group H member 3 decreases expression ISO lead nitrate results in decreased expression of NR1H3 mRNA CTD PMID:15475176 NCBI chr11:47,248,300...47,269,033
Ensembl chr11:47,248,300...47,269,033
JBrowse link
G NR5A2 nuclear receptor subfamily 5 group A member 2 increases expression ISO lead nitrate results in increased expression of NR5A2 mRNA CTD PMID:16049268 NCBI chr 1:200,027,710...200,177,415
Ensembl chr 1:200,027,614...200,177,420
JBrowse link
G NUMB NUMB endocytic adaptor protein multiple interactions ISO lead nitrate affects the reaction [NUMB affects the expression of MT1 mRNA]; lead nitrate affects the reaction [NUMB affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr14:73,275,216...73,458,546
Ensembl chr14:73,275,107...73,458,617
JBrowse link
G ODF1 outer dense fiber of sperm tails 1 decreases expression ISO lead nitrate results in decreased expression of ODF1 mRNA CTD PMID:21628963 NCBI chr 8:102,551,589...102,561,018
Ensembl chr 8:102,551,589...102,561,018
JBrowse link
G PAQR5 progestin and adipoQ receptor family member 5 decreases expression ISO lead nitrate results in decreased expression of PAQR5 mRNA CTD PMID:21628963 NCBI chr15:69,284,134...69,407,780
Ensembl chr15:69,298,912...69,407,780
JBrowse link
G PIAS2 protein inhibitor of activated STAT 2 multiple interactions ISO lead nitrate affects the reaction [PIAS2 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [PIAS2 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr18:46,803,218...46,920,167
Ensembl chr18:46,803,218...46,920,160
JBrowse link
G PLA2G4A phospholipase A2 group IVA multiple interactions
increases expression
EXP 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[lead nitrate results in increased expression of PLA2G4A mRNA] which results in increased secretion of Dinoprostone]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [lead nitrate results in increased expression of PLA2G4A mRNA]; 2-aminoethoxydiphenyl borate inhibits the reaction [lead nitrate results in increased expression of PLA2G4A mRNA]; 4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline inhibits the reaction [[lead nitrate results in increased expression of PLA2G4A mRNA] which results in increased secretion of Dinoprostone]; 4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline inhibits the reaction [lead nitrate results in increased expression of PLA2G4A mRNA]; [lead nitrate results in increased expression of PLA2G4A mRNA] which results in increased secretion of Dinoprostone; EGFR mutant form affects the reaction [[lead nitrate results in increased expression of PLA2G4A mRNA] which results in increased secretion of Dinoprostone]; EGFR mutant form affects the reaction [lead nitrate results in increased expression of PLA2G4A mRNA]; EGFR promotes the reaction [lead nitrate results in increased expression of PLA2G4A mRNA]; RTKI cpd inhibits the reaction [[lead nitrate results in increased expression of PLA2G4A mRNA] which results in increased secretion of Dinoprostone]; RTKI cpd inhibits the reaction [lead nitrate results in increased expression of PLA2G4A mRNA] CTD PMID:20850495 NCBI chr 1:186,828,949...186,988,981
Ensembl chr 1:186,828,949...186,988,981
JBrowse link
G POLD1 DNA polymerase delta 1, catalytic subunit multiple interactions ISO lead nitrate affects the reaction [POLD1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [POLD1 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr19:50,384,291...50,418,018
Ensembl chr19:50,384,204...50,418,018
JBrowse link
G POU3F3 POU class 3 homeobox 3 multiple interactions ISO lead nitrate affects the reaction [POU3F3 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [POU3F3 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr 2:104,854,115...104,858,574
Ensembl chr 2:104,853,287...104,858,574
Ensembl chr 2:104,853,287...104,858,574
JBrowse link
G PRM1 protamine 1 decreases expression ISO lead nitrate results in decreased expression of PRM1 mRNA CTD PMID:21628963 NCBI chr16:11,280,841...11,281,330
Ensembl chr16:11,280,841...11,281,330
JBrowse link
G PRM3 protamine 3 decreases expression ISO lead nitrate results in decreased expression of PRM3 mRNA CTD PMID:21628963 NCBI chr16:11,273,199...11,273,629
Ensembl chr16:11,273,199...11,273,629
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases expression
EXP 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[lead nitrate results in increased expression of PTGS2 mRNA] which results in increased secretion of Dinoprostone]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [lead nitrate results in increased expression of PTGS2 mRNA]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [lead nitrate results in increased expression of PTGS2 mRNA]; 4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline inhibits the reaction [[lead nitrate results in increased expression of PTGS2 mRNA] which results in increased secretion of Dinoprostone]; 4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline inhibits the reaction [lead nitrate results in increased expression of PTGS2 mRNA]; 4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline inhibits the reaction [lead nitrate results in increased expression of PTGS2 protein]; [lead nitrate results in increased expression of PTGS2 mRNA] which results in increased secretion of Dinoprostone; Decitabine promotes the reaction [lead nitrate results in increased expression of PTGS2 mRNA]; E2F1 protein inhibits the reaction [lead nitrate results in increased expression of PTGS2 mRNA]; lead nitrate inhibits the reaction [E2F1 protein results in decreased expression of PTGS2 mRNA]; lead nitrate promotes the reaction [RB1 protein results in increased expression of PTGS2 mRNA]; RB1 protein promotes the reaction [lead nitrate results in increased expression of PTGS2 mRNA]; RTKI cpd inhibits the reaction [[lead nitrate results in increased expression of PTGS2 mRNA] which results in increased secretion of Dinoprostone]; RTKI cpd inhibits the reaction [lead nitrate results in increased expression of PTGS2 mRNA]; RTKI cpd inhibits the reaction [lead nitrate results in increased expression of PTGS2 protein]
lead nitrate results in increased expression of PTGS2 mRNA; lead nitrate results in increased expression of PTGS2 protein
CTD PMID:20850495, PMID:21435385, PMID:24639330 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,423
JBrowse link
G RB1 RB transcriptional corepressor 1 multiple interactions
increases expression
EXP 4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline inhibits the reaction [lead nitrate results in increased expression of RB1 mRNA]; 4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline inhibits the reaction [lead nitrate results in increased expression of RB1 protein]; lead nitrate promotes the reaction [RB1 protein results in increased expression of PTGS2 mRNA]; RB1 protein promotes the reaction [lead nitrate results in increased expression of PTGS2 mRNA]; RTKI cpd inhibits the reaction [lead nitrate results in increased expression of RB1 mRNA]; RTKI cpd inhibits the reaction [lead nitrate results in increased expression of RB1 protein] CTD PMID:24639330 NCBI chr13:48,303,751...48,481,890
Ensembl chr13:48,303,744...48,599,436
Ensembl chr13:48,303,744...48,599,436
JBrowse link
G RBL2 RB transcriptional corepressor like 2 multiple interactions ISO lead nitrate affects the reaction [RBL2 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [RBL2 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr16:53,434,471...53,491,648
Ensembl chr16:53,433,977...53,491,648
JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit multiple interactions
increases expression
ISO mangiferin inhibits the reaction [lead nitrate results in increased expression of RELA protein] CTD PMID:23451106 NCBI chr11:65,653,601...65,662,946
Ensembl chr11:65,653,597...65,663,090
JBrowse link
G RIBC2 RIB43A domain with coiled-coils 2 decreases expression ISO lead nitrate results in decreased expression of RIBC2 mRNA CTD PMID:21628963 NCBI chr22:45,413,693...45,432,509
Ensembl chr22:45,413,693...45,432,509
JBrowse link
G RPS6KB1 ribosomal protein S6 kinase B1 increases phosphorylation
multiple interactions
ISO lead nitrate results in increased phosphorylation of RPS6KB1 protein
puerarin inhibits the reaction [lead nitrate results in increased phosphorylation of RPS6KB1 protein]
CTD PMID:27762461 NCBI chr17:59,893,121...59,950,574
Ensembl chr17:59,893,046...59,950,574
JBrowse link
G RUNX1 RUNX family transcription factor 1 multiple interactions ISO lead nitrate affects the reaction [RUNX1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [RUNX1 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr21:34,787,801...35,049,334
Ensembl chr21:34,787,801...36,004,667
JBrowse link
G RUNX2 RUNX family transcription factor 2 multiple interactions ISO [lead nitrate results in increased abundance of Lead] which results in decreased expression of RUNX2 mRNA; [lead nitrate results in increased abundance of Lead] which results in decreased expression of RUNX2 protein; icaritin inhibits the reaction [[lead nitrate results in increased abundance of Lead] which results in decreased expression of RUNX2 mRNA]; icaritin inhibits the reaction [[lead nitrate results in increased abundance of Lead] which results in decreased expression of RUNX2 protein] CTD PMID:30731080 NCBI chr 6:45,328,330...45,551,082
Ensembl chr 6:45,328,157...45,664,349
JBrowse link
G SMCP sperm mitochondria associated cysteine rich protein decreases expression ISO lead nitrate results in decreased expression of SMCP mRNA CTD PMID:21628963 NCBI chr 1:152,878,322...152,885,047
Ensembl chr 1:152,878,322...152,885,047
JBrowse link
G SNCA synuclein alpha affects localization
multiple interactions
increases expression
ISO lead nitrate affects the localization of SNCA protein
MT1 protein promotes the reaction [lead nitrate results in increased expression of SNCA mRNA]
CTD PMID:19542206 NCBI chr 4:89,724,099...89,838,324
Ensembl chr 4:89,700,345...89,838,315
Ensembl chr 4:89,700,345...89,838,315
JBrowse link
G SOCS1 suppressor of cytokine signaling 1 multiple interactions ISO lead nitrate affects the reaction [SOCS1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [SOCS1 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr16:11,254,417...11,256,182
Ensembl chr16:11,254,408...11,256,204
Ensembl chr16:11,254,408...11,256,204
JBrowse link
G SOD1 superoxide dismutase 1 multiple interactions
decreases activity
ISO Ashwagandha inhibits the reaction [lead nitrate results in decreased activity of SOD1 protein] CTD PMID:24987671 NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,622...31,668,931
Ensembl chr21:31,659,622...31,668,931
JBrowse link
G SP3 Sp3 transcription factor multiple interactions
decreases expression
ISO lead nitrate affects the reaction [SP3 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [SP3 affects the expression of MT2 mRNA]
lead nitrate results in decreased expression of SP3 mRNA
CTD PMID:11891201 NCBI chr 2:173,900,775...173,965,702
Ensembl chr 2:173,880,850...173,965,702
JBrowse link
G SPATA18 spermatogenesis associated 18 decreases expression ISO lead nitrate results in decreased expression of SPATA18 mRNA CTD PMID:21628963 NCBI chr 4:52,051,304...52,097,299
Ensembl chr 4:52,051,304...52,097,299
JBrowse link
G SPATA20 spermatogenesis associated 20 decreases expression ISO lead nitrate results in decreased expression of SPATA20 mRNA CTD PMID:21628963 NCBI chr17:50,547,174...50,555,852
Ensembl chr17:50,543,058...50,555,852
JBrowse link
G SPATA21 spermatogenesis associated 21 decreases expression ISO lead nitrate results in decreased expression of SPATA21 mRNA CTD PMID:21628963 NCBI chr 1:16,395,606...16,437,842
Ensembl chr 1:16,387,117...16,437,424
JBrowse link
G SPATA6 spermatogenesis associated 6 decreases expression ISO lead nitrate results in decreased expression of SPATA6 mRNA CTD PMID:21628963 NCBI chr 1:48,258,643...48,472,204
Ensembl chr 1:48,295,373...48,472,208
JBrowse link
G SQSTM1 sequestosome 1 multiple interactions
increases expression
ISO lead nitrate affects the reaction [SQSTM1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [SQSTM1 affects the expression of MT2 mRNA]
puerarin inhibits the reaction [lead nitrate results in increased expression of SQSTM1 protein]
CTD PMID:11891201, PMID:27762461 NCBI chr 5:179,806,393...179,838,078
Ensembl chr 5:179,806,398...179,838,078
JBrowse link
G SREBF2 sterol regulatory element binding transcription factor 2 increases expression ISO lead nitrate results in increased expression of SREBF2 mRNA CTD PMID:15475176, PMID:16705668 NCBI chr22:41,833,105...41,907,308
Ensembl chr22:41,833,079...41,907,307
JBrowse link
G SUMO1 small ubiquitin like modifier 1 multiple interactions ISO lead nitrate affects the reaction [SUMO1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [SUMO1 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr 2:202,206,171...202,238,597
Ensembl chr 2:202,206,180...202,238,608
Ensembl chr 2:202,206,180...202,238,608
JBrowse link
G TBX2 T-box transcription factor 2 multiple interactions ISO lead nitrate affects the reaction [TBX2 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [TBX2 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr17:61,399,843...61,409,466
Ensembl chr17:61,399,843...61,409,466
JBrowse link
G TEKT2 tektin 2 decreases expression ISO lead nitrate results in decreased expression of TEKT2 mRNA CTD PMID:21628963 NCBI chr 1:36,084,094...36,088,275
Ensembl chr 1:36,084,094...36,088,275
JBrowse link
G TEKT4 tektin 4 decreases expression ISO lead nitrate results in decreased expression of TEKT4 mRNA CTD PMID:21628963 NCBI chr 2:94,871,430...94,876,823
Ensembl chr 2:94,871,430...94,876,823
JBrowse link
G TMOD1 tropomodulin 1 decreases expression ISO lead nitrate results in decreased expression of TMOD1 mRNA CTD PMID:21628963 NCBI chr 9:97,501,180...97,601,743
Ensembl chr 9:97,501,180...97,601,743
JBrowse link
G TNF tumor necrosis factor multiple interactions
increases expression
ISO [IL1A gene mutant form co-treated with IL1B gene mutant form] inhibits the reaction [lead nitrate results in increased expression of TNF mRNA]
Lead nitrate increases expression of Tnf mRNA in liver
CTD PMID:15475176, PMID:16049268, PMID:22293356, PMID:9049203 RGD:14995487 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
G TNFRSF1A TNF receptor superfamily member 1A multiple interactions ISO lead nitrate affects the reaction [TNFRSF1A affects the expression of MT1 mRNA]; lead nitrate affects the reaction [TNFRSF1A affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr12:6,328,771...6,342,076
Ensembl chr12:6,328,757...6,342,114
JBrowse link
G TNFRSF1B TNF receptor superfamily member 1B multiple interactions ISO lead nitrate affects the reaction [TNFRSF1B affects the expression of MT1 mRNA]; lead nitrate affects the reaction [TNFRSF1B affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr 1:12,166,948...12,209,222
Ensembl chr 1:12,166,991...12,209,228
JBrowse link
G TNP1 transition protein 1 decreases expression ISO lead nitrate results in decreased expression of TNP1 mRNA CTD PMID:21628963 NCBI chr 2:216,859,458...216,860,064
Ensembl chr 2:216,859,458...216,860,064
JBrowse link
G TNP2 transition protein 2 decreases expression ISO lead nitrate results in decreased expression of TNP2 mRNA CTD PMID:21628963 NCBI chr16:11,267,857...11,269,325
Ensembl chr16:11,267,748...11,269,533
JBrowse link
G TP53 tumor protein p53 multiple interactions EXP [lead nitrate results in increased abundance of Lead] which results in increased expression of TP53 mRNA; titanium dioxide inhibits the reaction [[lead nitrate results in increased abundance of Lead] which results in increased expression of TP53 mRNA] CTD PMID:30738203 NCBI chr17:7,668,402...7,687,550
Ensembl chr17:7,661,779...7,687,538
Ensembl chr17:7,661,779...7,687,538
JBrowse link
G TPPP2 tubulin polymerization promoting protein family member 2 decreases expression ISO lead nitrate results in decreased expression of TPPP2 mRNA CTD PMID:21628963 NCBI chr14:21,024,262...21,036,352
Ensembl chr14:21,024,109...21,036,276
JBrowse link
G TRIM27 tripartite motif containing 27 multiple interactions ISO lead nitrate affects the reaction [TRIM27 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [TRIM27 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr 6:28,903,002...28,923,985
Ensembl chr 6:28,903,002...28,923,988
JBrowse link
G TRPM2 transient receptor potential cation channel subfamily M member 2 multiple interactions EXP lead nitrate inhibits the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein] CTD PMID:22750002 NCBI chr21:44,350,112...44,443,081
Ensembl chr21:44,350,163...44,443,081
JBrowse link
G TSC22D3 TSC22 domain family member 3 multiple interactions ISO [lead nitrate results in increased abundance of Lead] inhibits the reaction [Hydrocortisone results in increased expression of TSC22D3 mRNA] CTD PMID:29957541 NCBI chr  X:107,713,221...107,777,329
Ensembl chr  X:107,713,221...107,777,342
JBrowse link
G TSG101 tumor susceptibility 101 multiple interactions ISO lead nitrate affects the reaction [TSG101 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [TSG101 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr11:18,480,311...18,526,942
Ensembl chr11:18,468,336...18,526,951
JBrowse link
G TSSK2 testis specific serine kinase 2 decreases expression ISO lead nitrate results in decreased expression of TSSK2 mRNA CTD PMID:21628963 NCBI chr22:19,131,308...19,132,622
Ensembl chr22:19,131,308...19,132,622
JBrowse link
G TSSK3 testis specific serine kinase 3 decreases expression ISO lead nitrate results in decreased expression of TSSK3 mRNA CTD PMID:21628963 NCBI chr 1:32,352,720...32,365,265
Ensembl chr 1:32,351,521...32,364,312
JBrowse link
G TTF1 transcription termination factor 1 multiple interactions ISO lead nitrate affects the reaction [TTF1 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [TTF1 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr 9:132,375,548...132,406,840
Ensembl chr 9:132,375,548...132,406,851
JBrowse link
G TUBA8 tubulin alpha 8 decreases expression ISO lead nitrate results in decreased expression of TUBA8 mRNA CTD PMID:21628963 NCBI chr22:18,110,809...18,131,732
Ensembl chr22:18,110,331...18,146,554
JBrowse link
G TULP2 TUB like protein 2 decreases expression ISO lead nitrate results in decreased expression of TULP2 mRNA CTD PMID:21628963 NCBI chr19:48,880,817...48,900,221
Ensembl chr19:48,880,967...48,898,744
JBrowse link
G WNT3A Wnt family member 3A multiple interactions ISO [lead nitrate results in increased abundance of Lead] which results in decreased expression of WNT3A mRNA; [lead nitrate results in increased abundance of Lead] which results in decreased expression of WNT3A protein; icaritin inhibits the reaction [[lead nitrate results in increased abundance of Lead] which results in decreased expression of WNT3A mRNA]; icaritin inhibits the reaction [[lead nitrate results in increased abundance of Lead] which results in decreased expression of WNT3A protein] CTD PMID:30731080 NCBI chr 1:228,006,998...228,067,113
Ensembl chr 1:228,006,998...228,061,271
JBrowse link
G WNT4 Wnt family member 4 multiple interactions ISO lead nitrate affects the reaction [WNT4 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [WNT4 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr 1:22,117,308...22,143,981
Ensembl chr 1:22,117,313...22,143,969
JBrowse link
G ZFHX3 zinc finger homeobox 3 multiple interactions ISO lead nitrate affects the reaction [ZFHX3 affects the expression of MT1 mRNA]; lead nitrate affects the reaction [ZFHX3 affects the expression of MT2 mRNA] CTD PMID:11891201 NCBI chr16:72,782,885...73,891,931
Ensembl chr16:72,782,885...73,891,871
JBrowse link
G ZNRF4 zinc and ring finger 4 decreases expression ISO lead nitrate results in decreased expression of ZNRF4 mRNA CTD PMID:21628963 NCBI chr19:5,455,417...5,456,856
Ensembl chr19:5,455,417...5,456,856
JBrowse link
potassium nitrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCDC120 coiled-coil domain containing 120 decreases expression EXP potassium nitrate results in decreased expression of CCDC120 mRNA CTD PMID:15878651 NCBI chr  X:49,053,572...49,069,858
Ensembl chr  X:49,053,572...49,069,857
JBrowse link
G CLK1 CDC like kinase 1 decreases expression EXP potassium nitrate results in decreased expression of CLK1 mRNA CTD PMID:15878651 NCBI chr 2:200,853,009...200,864,658
Ensembl chr 2:200,853,009...200,864,744
JBrowse link
G DCLRE1C DNA cross-link repair 1C increases expression EXP potassium nitrate results in increased expression of DCLRE1C mRNA CTD PMID:15878651 NCBI chr10:14,897,359...14,954,432
Ensembl chr10:14,897,359...14,954,432
JBrowse link
G FTH1 ferritin heavy chain 1 increases expression EXP potassium nitrate results in increased expression of FTH1 mRNA CTD PMID:15878651 NCBI chr11:61,964,285...61,967,634
Ensembl chr11:61,959,718...61,967,634
JBrowse link
G FTL ferritin light chain increases expression EXP potassium nitrate results in increased expression of FTL mRNA CTD PMID:15878651 NCBI chr19:48,963,941...48,966,879
Ensembl chr19:48,965,309...48,966,879
JBrowse link
G HMGB1 high mobility group box 1 increases expression EXP potassium nitrate results in increased expression of HMGB1 mRNA CTD PMID:15878651 NCBI chr13:30,456,704...30,617,597
Ensembl chr13:30,456,704...30,617,597
JBrowse link
G HMGB2 high mobility group box 2 increases expression EXP potassium nitrate results in increased expression of HMGB2 mRNA CTD PMID:15878651 NCBI chr 4:173,331,376...173,334,358
Ensembl chr 4:173,331,376...173,334,432
JBrowse link
G PCNA proliferating cell nuclear antigen increases expression EXP potassium nitrate results in increased expression of PCNA mRNA CTD PMID:15878651 NCBI chr20:5,114,953...5,126,622
Ensembl chr20:5,114,953...5,126,626
JBrowse link
G SEPTIN7 septin 7 decreases expression EXP potassium nitrate results in decreased expression of SEPTIN7 mRNA CTD PMID:15878651 NCBI chr 7:35,800,986...35,915,763
Ensembl chr 7:35,800,932...35,907,105
JBrowse link
G STMN1 stathmin 1 increases expression EXP potassium nitrate results in increased expression of STMN1 mRNA CTD PMID:15878651 NCBI chr 1:25,884,179...25,906,880
Ensembl chr 1:25,884,181...25,906,991
JBrowse link
G VEGFA vascular endothelial growth factor A decreases expression EXP potassium nitrate results in decreased expression of VEGFA mRNA CTD PMID:15878651 NCBI chr 6:43,770,209...43,786,487
Ensembl chr 6:43,770,184...43,786,487
JBrowse link
silver(1+) nitrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC1 ATP binding cassette subfamily C member 1 multiple interactions
increases response to substance
EXP [ABCC1 protein results in increased susceptibility to Silver Nitrate] which results in decreased export of calcein AM CTD PMID:27376922 NCBI chr16:15,949,616...16,143,062
Ensembl chr16:15,949,577...16,143,074
JBrowse link
G ATM ATM serine/threonine kinase increases expression EXP Silver Nitrate analog results in increased expression of ATM mRNA CTD PMID:22831968 NCBI chr11:108,222,484...108,369,102
Ensembl chr11:108,222,832...108,369,102
Ensembl chr11:108,222,832...108,369,102
JBrowse link
G ATR ATR serine/threonine kinase increases expression EXP Silver Nitrate analog results in increased expression of ATR mRNA CTD PMID:22831968 NCBI chr 3:142,449,235...142,578,793
Ensembl chr 3:142,449,007...142,578,733
JBrowse link
G AURKA aurora kinase A increases expression
multiple interactions
EXP Silver Nitrate results in increased expression of AURKA protein modified form
CFL1 mRNA promotes the reaction [Silver Nitrate results in increased expression of AURKA protein modified form]
CTD PMID:28499611 NCBI chr20:56,369,390...56,392,308
Ensembl chr20:56,369,389...56,392,337
JBrowse link
G AURKB aurora kinase B multiple interactions
increases phosphorylation
EXP CFL1 mRNA promotes the reaction [Silver Nitrate results in increased phosphorylation of AURKB protein] CTD PMID:28499611 NCBI chr17:8,204,731...8,210,767
Ensembl chr17:8,204,733...8,210,600
JBrowse link
G AURKC aurora kinase C increases expression
multiple interactions
EXP Silver Nitrate results in increased expression of AURKC protein modified form
CFL1 mRNA promotes the reaction [Silver Nitrate results in increased expression of AURKC protein modified form]
CTD PMID:28499611 NCBI chr19:57,230,317...57,235,550
Ensembl chr19:57,230,802...57,235,548
JBrowse link
G BUB1 BUB1 mitotic checkpoint serine/threonine kinase increases expression EXP Silver Nitrate analog results in increased expression of BUB1 mRNA; Silver Nitrate results in increased expression of BUB1 mRNA CTD PMID:22831968 NCBI chr 2:110,637,528...110,678,063
Ensembl chr 2:110,637,528...110,678,063
JBrowse link
G BUB1B BUB1 mitotic checkpoint serine/threonine kinase B increases expression EXP Silver Nitrate analog results in increased expression of BUB1B mRNA; Silver Nitrate results in increased expression of BUB1B mRNA CTD PMID:22831968 NCBI chr15:40,161,069...40,221,123
Ensembl chr15:40,161,023...40,221,136
Ensembl chr15:40,161,023...40,221,136
JBrowse link
G CAT catalase increases expression EXP Silver Nitrate results in increased expression of CAT mRNA CTD PMID:19508889 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
JBrowse link
G CCNA2 cyclin A2 decreases expression EXP Silver Nitrate analog results in decreased expression of CCNA2 mRNA CTD PMID:22831968 NCBI chr 4:121,816,444...121,823,883
Ensembl chr 4:121,816,444...121,823,883
Ensembl chr 4:121,816,444...121,823,883
JBrowse link
G CCNB1 cyclin B1 decreases expression EXP Silver Nitrate analog results in decreased expression of CCNB1 mRNA; Silver Nitrate results in decreased expression of CCNB1 mRNA CTD PMID:22831968 NCBI chr 5:69,167,150...69,178,245
Ensembl chr 5:69,167,135...69,178,245
JBrowse link
G CCNE1 cyclin E1 increases expression EXP Silver Nitrate analog results in increased expression of CCNE1 mRNA; Silver Nitrate results in increased expression of CCNE1 mRNA CTD PMID:22831968 NCBI chr19:29,811,991...29,824,312
Ensembl chr19:29,811,991...29,824,312
JBrowse link
G CD28 CD28 molecule multiple interactions
affects response to substance
ISO CD28 protein affects the reaction [Silver Nitrate results in decreased activity of FBL protein]
CD28 protein affects the susceptibility to Silver Nitrate
CTD PMID:19077085 NCBI chr 2:203,706,509...203,739,756
Ensembl chr 2:203,706,475...203,738,912
JBrowse link
G CDC14A cell division cycle 14A increases expression EXP Silver Nitrate analog results in increased expression of CDC14A mRNA CTD PMID:22831968 NCBI chr 1:100,345,001...100,520,281
Ensembl chr 1:100,345,001...100,520,277
JBrowse link
G CDC25B cell division cycle 25B affects expression EXP Silver Nitrate analog affects the expression of CDC25B mRNA CTD PMID:22831968 NCBI chr20:3,786,951...3,806,118
Ensembl chr20:3,786,772...3,806,121
JBrowse link
G CDC25C cell division cycle 25C affects expression EXP Silver Nitrate analog affects the expression of CDC25C mRNA CTD PMID:22831968 NCBI chr 5:138,285,265...138,338,355
Ensembl chr 5:138,285,265...138,338,355
JBrowse link
G CDC45 cell division cycle 45 increases expression EXP Silver Nitrate analog results in increased expression of CDC45 mRNA; Silver Nitrate results in increased expression of CDC45 mRNA CTD PMID:22831968 NCBI chr22:19,479,294...19,520,612
Ensembl chr22:19,479,457...19,520,612
JBrowse link
G CDC6 cell division cycle 6 increases expression EXP Silver Nitrate analog results in increased expression of CDC6 mRNA; Silver Nitrate results in increased expression of CDC6 mRNA CTD PMID:22831968 NCBI chr17:40,287,878...40,304,657
Ensembl chr17:40,287,879...40,304,657
JBrowse link
G CDC7 cell division cycle 7 affects expression
increases expression
EXP Silver Nitrate analog affects the expression of CDC7 mRNA
Silver Nitrate results in increased expression of CDC7 mRNA
CTD PMID:22831968 NCBI chr 1:91,498,968...91,525,764
Ensembl chr 1:91,500,851...91,525,764
JBrowse link
G CDK1 cyclin dependent kinase 1 affects expression EXP Silver Nitrate analog affects the expression of CDK1 mRNA CTD PMID:22831968 NCBI chr10:60,778,331...60,794,852
Ensembl chr10:60,778,331...60,794,852
JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A increases expression EXP Silver Nitrate results in increased expression of CDKN2A mRNA CTD PMID:22831968 NCBI chr 9:21,967,752...21,995,324
Ensembl chr 9:21,967,753...21,995,301
JBrowse link
G CDKN2C cyclin dependent kinase inhibitor 2C affects expression EXP Silver Nitrate analog affects the expression of CDKN2C mRNA CTD PMID:22831968 NCBI chr 1:50,968,706...50,974,634
Ensembl chr 1:50,960,745...50,974,634
JBrowse link
G CFL1 cofilin 1 multiple interactions EXP CFL1 mRNA promotes the reaction [Silver Nitrate results in increased expression of AURKA protein modified form]; CFL1 mRNA promotes the reaction [Silver Nitrate results in increased expression of AURKC protein modified form]; CFL1 mRNA promotes the reaction [Silver Nitrate results in increased phosphorylation of AURKB protein] CTD PMID:28499611 NCBI chr11:65,854,673...65,858,180
Ensembl chr11:65,823,022...65,862,026
JBrowse link
G CHEK1 checkpoint kinase 1 increases expression EXP Silver Nitrate analog results in increased expression of CHEK1 mRNA CTD PMID:22831968 NCBI chr11:125,624,910...125,676,256
Ensembl chr11:125,625,665...125,676,255
JBrowse link
G CHEK2 checkpoint kinase 2 increases expression EXP Silver Nitrate analog results in increased expression of CHEK2 mRNA CTD PMID:22831968 NCBI chr22:28,687,743...28,741,866
Ensembl chr22:28,687,743...28,742,422
JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 increases expression EXP Silver Nitrate results in increased expression of CXCL8 mRNA CTD PMID:20491607 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,541...73,743,716
JBrowse link
G DBF4 DBF4 zinc finger increases expression EXP Silver Nitrate analog results in increased expression of DBF4 mRNA; Silver Nitrate results in increased expression of DBF4 mRNA CTD PMID:22831968 NCBI chr 7:87,876,493...87,909,553
Ensembl chr 7:87,876,216...87,909,553
JBrowse link
G DNAJA1 DnaJ heat shock protein family (Hsp40) member A1 increases expression EXP Silver Nitrate analog results in increased expression of DNAJA1 mRNA CTD PMID:22831968 NCBI chr 9:33,025,273...33,039,907
Ensembl chr 9:33,025,273...33,039,907
JBrowse link
G DNAJB1 DnaJ heat shock protein family (Hsp40) member B1 increases expression EXP Silver Nitrate analog results in increased expression of DNAJB1 mRNA CTD PMID:22831968 NCBI chr19:14,514,769...14,530,597
Ensembl chr19:14,514,769...14,529,770
JBrowse link
G DNAJC19 DnaJ heat shock protein family (Hsp40) member C19 decreases expression EXP Silver Nitrate analog results in decreased expression of DNAJC19 mRNA CTD PMID:22831968 NCBI chr 3:180,983,709...180,989,838
Ensembl chr 3:180,983,709...180,989,774
JBrowse link
G E2F1 E2F transcription factor 1 increases expression EXP Silver Nitrate analog results in increased expression of E2F1 mRNA CTD PMID:22831968 NCBI chr20:33,675,477...33,686,385
Ensembl chr20:33,675,477...33,686,385
JBrowse link
G E2F2 E2F transcription factor 2 increases expression EXP Silver Nitrate analog results in increased expression of E2F2 mRNA CTD PMID:22831968 NCBI chr 1:23,505,696...23,531,250
Ensembl chr 1:23,506,438...23,531,233
JBrowse link
G E2F3 E2F transcription factor 3 increases expression EXP Silver Nitrate analog results in increased expression of E2F3 mRNA CTD PMID:22831968 NCBI chr 6:20,401,879...20,493,714
Ensembl chr 6:20,401,879...20,493,714
JBrowse link
G E2F4 E2F transcription factor 4 increases expression EXP Silver Nitrate results in increased expression of E2F4 mRNA CTD PMID:22831968 NCBI chr16:67,192,155...67,198,918
Ensembl chr16:67,192,155...67,198,918
JBrowse link
G E2F5 E2F transcription factor 5 increases expression EXP Silver Nitrate results in increased expression of E2F5 mRNA CTD PMID:22831968 NCBI chr 8:85,177,154...85,214,518
Ensembl chr 8:85,177,154...85,217,158
JBrowse link
G FBL fibrillarin multiple interactions
decreases activity
ISO CD28 protein affects the reaction [Silver Nitrate results in decreased activity of FBL protein]; IFNG protein affects the reaction [Silver Nitrate results in decreased activity of FBL protein]; IL4 protein affects the reaction [Silver Nitrate results in decreased activity of FBL protein]; IL6 protein affects the reaction [Silver Nitrate results in decreased activity of FBL protein] CTD PMID:19077085 NCBI chr19:39,834,458...39,846,395
Ensembl chr19:39,834,458...39,846,379
JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit increases expression EXP Silver Nitrate results in increased expression of FOS mRNA CTD PMID:10362023 NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,282,230
JBrowse link
G FOSB FosB proto-oncogene, AP-1 transcription factor subunit decreases expression EXP Silver Nitrate results in decreased expression of FOSB mRNA CTD PMID:27180073 NCBI chr19:45,467,996...45,475,179
Ensembl chr19:45,467,995...45,475,179
JBrowse link
G G6PD glucose-6-phosphate dehydrogenase decreases activity ISO Silver Nitrate results in decreased activity of G6PD protein CTD PMID:28557068 NCBI chr  X:154,531,390...154,547,569
Ensembl chr  X:154,531,391...154,547,572
JBrowse link
G GCLC glutamate-cysteine ligase catalytic subunit decreases expression EXP Silver Nitrate results in decreased expression of GCLC mRNA CTD PMID:19733233 NCBI chr 6:53,497,341...53,545,101
Ensembl chr 6:53,497,341...53,616,970
JBrowse link
G GPX1 glutathione peroxidase 1 increases expression EXP Silver Nitrate results in increased expression of GPX1 mRNA CTD PMID:19508889 NCBI chr 3:49,357,176...49,358,353
Ensembl chr 3:49,357,176...49,358,358
JBrowse link
G GPX7 glutathione peroxidase 7 increases expression EXP Silver Nitrate results in increased expression of GPX7 mRNA CTD PMID:27180073 NCBI chr 1:52,602,371...52,609,051
Ensembl chr 1:52,602,371...52,609,051
JBrowse link
G H1-3 H1.3 linker histone, cluster member decreases expression EXP Silver Nitrate analog results in decreased expression of H1-3 mRNA CTD PMID:22831968 NCBI chr 6:26,234,212...26,234,987
Ensembl chr 6:26,234,268...26,234,933
Ensembl chr 6:26,234,268...26,234,933
JBrowse link
G H1-5 H1.5 linker histone, cluster member decreases expression EXP Silver Nitrate analog results in decreased expression of H1-5 mRNA; Silver Nitrate results in decreased expression of H1-5 mRNA CTD PMID:22831968 NCBI chr 6:27,866,792...27,867,588
Ensembl chr 6:27,866,849...27,867,529
Ensembl chr 6:27,866,849...27,867,529
JBrowse link
G HMOX1 heme oxygenase 1 multiple interactions
increases expression
EXP Silver Nitrate promotes the reaction [HSF1 protein binds to HMOX1 promoter]
Silver Nitrate results in increased expression of HMOX1 mRNA
CTD PMID:17244614, PMID:27180073 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,207
JBrowse link
G HSF1 heat shock transcription factor 1 multiple interactions
increases activity
EXP Silver Nitrate promotes the reaction [HSF1 protein binds to HMOX1 promoter]; Silver Nitrate promotes the reaction [HSF1 protein binds to HSPA1A enhancer]; Silver Nitrate promotes the reaction [HSF1 protein binds to HSPA1A promoter]
Silver Nitrate results in increased activity of HSF1 protein
CTD PMID:16460681, PMID:17244614 NCBI chr 8:144,291,603...144,314,720
Ensembl chr 8:144,291,591...144,314,720
JBrowse link
G HSP90AA1 heat shock protein 90 alpha family class A member 1 increases expression EXP Silver Nitrate analog results in increased expression of HSP90AA1 mRNA CTD PMID:22831968 NCBI chr14:102,080,742...102,139,749
Ensembl chr14:102,080,738...102,139,699
Ensembl chr14:102,080,738...102,139,699
JBrowse link
G HSP90AA2P heat shock protein 90 alpha family class A member 2, pseudogene increases expression EXP Silver Nitrate analog results in increased expression of HSP90AA2P mRNA CTD PMID:22831968 NCBI chr11:27,888,171...27,891,092
Ensembl chr11:27,888,838...27,891,033
JBrowse link
G HSP90AA4P heat shock protein 90 alpha family class A member 4, pseudogene increases expression EXP Silver Nitrate analog results in increased expression of HSP90AA4P mRNA CTD PMID:22831968 NCBI chr 4:189,472,906...189,475,853
Ensembl chr 4:189,472,965...189,475,192
JBrowse link
G HSP90AA5P heat shock protein 90 alpha family class A member 5, pseudogene increases expression EXP Silver Nitrate analog results in increased expression of HSP90AA5P mRNA CTD PMID:22831968 NCBI chr 3:184,115,842...184,118,003
Ensembl chr 3:184,115,352...184,117,898
JBrowse link
G HSP90AA6P heat shock protein 90 alpha family class A member 6, pseudogene increases expression EXP Silver Nitrate analog results in increased expression of HSP90AA6P mRNA; Silver Nitrate results in increased expression of HSP90AA6P mRNA CTD PMID:22831968 NCBI chr 4:170,604,715...170,605,458
Ensembl chr 4:170,581,470...170,605,450
JBrowse link
G HSP90AB2P heat shock protein 90 alpha family class B member 2, pseudogene increases expression EXP Silver Nitrate analog results in increased expression of HSP90AB2P mRNA CTD PMID:22831968 NCBI chr 4:13,336,387...13,338,931
Ensembl chr 4:13,333,414...13,338,657
JBrowse link
G HSP90AB6P heat shock protein 90 alpha family class B member 6, pseudogene increases expression EXP Silver Nitrate analog results in increased expression of HSP90AB6P mRNA CTD PMID:22831968 NCBI chr13:96,883,419...96,885,912
Ensembl chr13:96,883,842...96,885,821
JBrowse link
G HSPA12A heat shock protein family A (Hsp70) member 12A decreases expression EXP Silver Nitrate analog results in decreased expression of HSPA12A mRNA CTD PMID:22831968 NCBI chr10:116,671,192...116,853,272
Ensembl chr10:116,671,192...116,850,236
Ensembl chr10:116,671,192...116,850,236
JBrowse link
G HSPA12B heat shock protein family A (Hsp70) member 12B increases expression EXP Silver Nitrate analog results in increased expression of HSPA12B mRNA CTD PMID:22831968 NCBI chr20:3,732,685...3,753,111
Ensembl chr20:3,732,685...3,753,111
JBrowse link
G HSPA1A heat shock protein family A (Hsp70) member 1A multiple interactions
increases expression
EXP Silver Nitrate promotes the reaction [HSF1 protein binds to HSPA1A enhancer]; Silver Nitrate promotes the reaction [HSF1 protein binds to HSPA1A promoter]
Silver Nitrate results in increased expression of HSPA1A mRNA
CTD PMID:16460681, PMID:17244614, PMID:27180073 NCBI chr 6:31,815,543...31,817,942
Ensembl chr 6:31,815,543...31,817,946
JBrowse link
G HSPA6 heat shock protein family A (Hsp70) member 6 increases expression EXP Silver Nitrate analog results in increased expression of HSPA6 mRNA CTD PMID:22831968 NCBI chr 1:161,524,540...161,526,894
Ensembl chr 1:161,524,540...161,526,894
JBrowse link
G HSPA7 heat shock protein family A (Hsp70) member 7 (pseudogene) increases expression EXP Silver Nitrate analog results in increased expression of HSPA7 mRNA; Silver Nitrate results in increased expression of HSPA7 mRNA CTD PMID:22831968 NCBI chr 1:161,606,059...161,608,551
Ensembl chr 1:161,606,291...161,608,217
JBrowse link
G HSPB11 heat shock protein family B (small) member 11 decreases expression EXP Silver Nitrate analog results in decreased expression of HSPB11 mRNA CTD PMID:22831968 NCBI chr 1:53,916,573...53,946,305
Ensembl chr 1:53,916,574...53,945,929
JBrowse link
G HSPB9 heat shock protein family B (small) member 9 increases expression EXP Silver Nitrate analog results in increased expression of HSPB9 mRNA CTD PMID:22831968 NCBI chr17:42,122,804...42,123,352
Ensembl chr17:42,122,804...42,123,352
JBrowse link
G HSPH1 heat shock protein family H (Hsp110) member 1 increases expression EXP Silver Nitrate analog results in increased expression of HSPH1 mRNA CTD PMID:22831968 NCBI chr13:31,134,973...31,162,388
Ensembl chr13:31,134,973...31,162,388
JBrowse link
G IFNG interferon gamma affects response to substance
multiple interactions
ISO IFNG protein affects the susceptibility to Silver Nitrate
IFNG protein affects the reaction [Silver Nitrate results in decreased activity of FBL protein]
CTD PMID:19077085 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740
JBrowse link
G IL1B interleukin 1 beta increases expression ISO Silver Nitrate results in increased expression of IL1B protein CTD PMID:25527144 NCBI chr 2:112,829,751...112,836,843
Ensembl chr 2:112,829,751...112,836,816
JBrowse link
G IL4 interleukin 4 affects response to substance
multiple interactions
ISO IL4 protein affects the susceptibility to Silver Nitrate
IL4 protein affects the reaction [Silver Nitrate results in decreased activity of FBL protein]
CTD PMID:19077085 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678
JBrowse link
G IL6 interleukin 6 affects response to substance
multiple interactions
ISO IL6 protein affects the susceptibility to Silver Nitrate
IL6 protein affects the reaction [Silver Nitrate results in decreased activity of FBL protein]
CTD PMID:19077085 NCBI chr 7:22,725,889...22,732,002
Ensembl chr 7:22,725,884...22,732,002
JBrowse link
G KITLG KIT ligand increases expression EXP Silver Nitrate results in increased expression of KITLG mRNA CTD PMID:22831968 NCBI chr12:88,492,793...88,580,471
Ensembl chr12:88,492,793...88,580,851
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 increases phosphorylation ISO Silver Nitrate results in increased phosphorylation of MAPK1 protein CTD PMID:27624343 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,754,500...21,867,680
Ensembl chr22:21,754,500...21,867,680
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 increases phosphorylation ISO Silver Nitrate results in increased phosphorylation of MAPK3 protein CTD PMID:27624343 NCBI chr16:30,114,105...30,123,309
Ensembl chr16:30,114,105...30,123,506
JBrowse link
G MCM3 minichromosome maintenance complex component 3 decreases expression EXP Silver Nitrate analog results in decreased expression of MCM3 mRNA CTD PMID:22831968 NCBI chr 6:52,264,015...52,284,742
Ensembl chr 6:52,264,014...52,284,881
JBrowse link
G MCM4 minichromosome maintenance complex component 4 increases expression EXP Silver Nitrate results in increased expression of MCM4 mRNA CTD PMID:22831968 NCBI chr 8:47,960,941...47,978,160
Ensembl chr 8:47,960,185...47,978,160
JBrowse link
G MCM6 minichromosome maintenance complex component 6 increases expression EXP Silver Nitrate results in increased expression of MCM6 mRNA CTD PMID:22831968 NCBI chr 2:135,839,626...135,876,443
Ensembl chr 2:135,839,626...135,876,443
JBrowse link
G MT1A metallothionein 1A multiple interactions
increases expression
EXP MTF1 mutant form inhibits the reaction [Silver Nitrate results in increased expression of MT1A mRNA]
Silver Nitrate analog results in increased expression of MT1A mRNA; Silver Nitrate results in increased expression of MT1A mRNA
CTD PMID:19733233, PMID:22831968, PMID:23333424 NCBI chr16:56,638,666...56,640,087
Ensembl chr16:56,638,666...56,640,087
JBrowse link
G MT1B metallothionein 1B increases expression EXP Silver Nitrate analog results in increased expression of MT1B mRNA; Silver Nitrate results in increased expression of MT1B mRNA CTD PMID:19508889, PMID:22831968, PMID:27180073 NCBI chr16:56,651,886...56,653,204
Ensembl chr16:56,651,886...56,653,204
JBrowse link
G MT1E metallothionein 1E increases expression EXP Silver Nitrate analog results in increased expression of MT1E mRNA; Silver Nitrate results in increased expression of MT1E mRNA CTD PMID:22831968 NCBI chr16:56,625,781...56,627,112
Ensembl chr16:56,625,475...56,627,112
JBrowse link
G MT1F metallothionein 1F increases expression EXP Silver Nitrate analog results in increased expression of MT1F mRNA; Silver Nitrate results in increased expression of MT1F mRNA CTD PMID:22831968 NCBI chr16:56,657,959...56,659,303
Ensembl chr16:56,657,731...56,660,698
JBrowse link
G MT1H metallothionein 1H increases expression EXP Silver Nitrate analog results in increased expression of MT1H mRNA; Silver Nitrate results in increased expression of MT1H mRNA CTD PMID:22831968, PMID:27180073 NCBI chr16:56,669,814...56,671,129
Ensembl chr16:56,669,814...56,671,129
JBrowse link
G MT1X metallothionein 1X increases expression EXP
ISO
Silver Nitrate analog results in increased expression of MT1X mRNA; Silver Nitrate results in increased expression of MT1X mRNA
Silver Nitrate results in increased expression of MT1 mRNA
CTD PMID:22831968, PMID:27180073, PMID:27624343 NCBI chr16:56,682,470...56,684,196
Ensembl chr16:56,682,470...56,684,196
JBrowse link
G MT2A metallothionein 2A increases expression EXP
ISO
Silver Nitrate results in increased expression of MT2A mRNA
Silver Nitrate results in increased expression of MT2 mRNA
CTD PMID:10362023, PMID:20491607, PMID:23333424, PMID:27180073, PMID:27624343 NCBI chr16:56,608,584...56,609,497
Ensembl chr16:56,608,584...56,609,497
JBrowse link
G MT3 metallothionein 3 increases expression EXP Silver Nitrate analog results in increased expression of MT3 mRNA CTD PMID:22831968 NCBI chr16:56,589,528...56,591,085
Ensembl chr16:56,589,074...56,591,088
JBrowse link
G MT4 metallothionein 4 increases expression EXP Silver Nitrate analog results in increased expression of MT4 mRNA; Silver Nitrate results in increased expression of MT4 mRNA CTD PMID:22831968 NCBI chr16:56,565,073...56,568,957
Ensembl chr16:56,565,073...56,568,957
JBrowse link
G MTF1 metal regulatory transcription factor 1 multiple interactions
increases activity
EXP MTF1 mutant form inhibits the reaction [Silver Nitrate results in increased expression of MT1A mRNA]; MTF1 mutant form inhibits the reaction [Silver Nitrate results in increased expression of SLC30A1 mRNA]
Silver Nitrate results in increased activity of MTF1 protein
CTD PMID:19733233 NCBI chr 1:37,809,570...37,859,614
Ensembl chr 1:37,809,574...37,859,592
JBrowse link
G NFE2L2 nuclear factor, erythroid 2 like 2 decreases expression
increases activity
EXP Silver Nitrate results in decreased expression of NFE2L2 mRNA
Silver Nitrate results in increased activity of NFE2L2 protein
CTD PMID:19733233, PMID:23872425 NCBI chr 2:177,230,303...177,265,131
Ensembl chr 2:177,227,595...177,392,697
JBrowse link
G ORC6 origin recognition complex subunit 6 increases expression EXP Silver Nitrate results in increased expression of ORC6 mRNA CTD PMID:22831968 NCBI chr16:46,689,656...46,698,394
Ensembl chr16:46,689,643...46,698,394
JBrowse link
G PCNA proliferating cell nuclear antigen increases expression EXP Silver Nitrate analog results in increased expression of PCNA mRNA; Silver Nitrate results in increased expression of PCNA mRNA CTD PMID:22831968 NCBI chr20:5,114,953...5,126,622
Ensembl chr20:5,114,953...5,126,626
JBrowse link
G PLK1 polo like kinase 1 decreases expression EXP Silver Nitrate analog results in decreased expression of PLK1 mRNA CTD PMID:22831968 NCBI chr16:23,678,889...23,690,367
Ensembl chr16:23,677,656...23,690,367
JBrowse link
G PTTG1 PTTG1 regulator of sister chromatid separation, securin increases expression
affects expression
EXP Silver Nitrate results in increased expression of PTTG1 mRNA
Silver Nitrate analog affects the expression of PTTG1 mRNA
CTD PMID:22831968 NCBI chr 5:160,421,855...160,428,744
Ensembl chr 5:160,421,855...160,428,739
JBrowse link
G RBL1 RB transcriptional corepressor like 1 increases expression EXP Silver Nitrate analog results in increased expression of RBL1 mRNA; Silver Nitrate results in increased expression of RBL1 mRNA CTD PMID:22831968 NCBI chr20:36,996,349...37,096,029
Ensembl chr20:36,996,349...37,095,997
JBrowse link
G RBL2 RB transcriptional corepressor like 2 increases expression EXP Silver Nitrate analog results in increased expression of RBL2 mRNA; Silver Nitrate results in increased expression of RBL2 mRNA CTD PMID:22831968 NCBI chr16:53,434,471...53,491,648
Ensembl chr16:53,433,977...53,491,648
JBrowse link
G SKP2 S-phase kinase associated protein 2 increases expression EXP Silver Nitrate analog results in increased expression of SKP2 mRNA CTD PMID:22831968 NCBI chr 5:36,152,067...36,184,319
Ensembl chr 5:36,151,989...36,184,319
JBrowse link
G SLC30A1 solute carrier family 30 member 1 multiple interactions
increases expression
EXP MTF1 mutant form inhibits the reaction [Silver Nitrate results in increased expression of SLC30A1 mRNA] CTD PMID:19733233 NCBI chr 1:211,571,568...211,579,161
Ensembl chr 1:211,571,568...211,579,161
JBrowse link
G SLC31A1 solute carrier family 31 member 1 increases expression EXP Silver Nitrate results in increased expression of SLC31A1 mRNA CTD PMID:24132751 NCBI chr 9:113,221,544...113,264,492
Ensembl chr 9:113,221,544...113,264,492
JBrowse link
G SMAD2 SMAD family member 2 decreases expression
increases expression
EXP Silver Nitrate analog results in decreased expression of SMAD2 mRNA
Silver Nitrate results in increased expression of SMAD2 mRNA
CTD PMID:22831968 NCBI chr18:47,808,957...47,931,188
Ensembl chr18:47,808,957...47,931,146
JBrowse link
G SMAD3 SMAD family member 3 decreases expression
increases expression
EXP Silver Nitrate analog results in decreased expression of SMAD3 mRNA
Silver Nitrate results in increased expression of SMAD3 mRNA
CTD PMID:22831968 NCBI chr15:67,065,602...67,195,195
Ensembl chr15:67,063,763...67,195,169
JBrowse link
G SOD1 superoxide dismutase 1 increases expression EXP Silver Nitrate results in increased expression of SOD1 mRNA CTD PMID:19508889 NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,622...31,668,931
Ensembl chr21:31,659,622...31,668,931
JBrowse link
G SP1 Sp1 transcription factor increases expression EXP Silver Nitrate results in increased expression of SP1 mRNA CTD PMID:24132751 NCBI chr12:53,380,176...53,416,446
Ensembl chr12:53,380,176...53,416,446
JBrowse link
G TFDP1 transcription factor Dp-1 increases expression EXP Silver Nitrate analog results in increased expression of TFDP1 mRNA CTD PMID:22831968 NCBI chr13:113,584,688...113,641,473
Ensembl chr13:113,584,721...113,641,473
JBrowse link
G TFDP2 transcription factor Dp-2 increases expression EXP Silver Nitrate analog results in increased expression of TFDP2 mRNA CTD PMID:22831968 NCBI chr 3:141,944,428...142,149,544
Ensembl chr 3:141,944,428...142,149,544
JBrowse link
G TP53 tumor protein p53 decreases expression EXP Silver Nitrate analog results in decreased expression of TP53 mRNA CTD PMID:22831968 NCBI chr17:7,668,402...7,687,550
Ensembl chr17:7,661,779...7,687,538
Ensembl chr17:7,661,779...7,687,538
JBrowse link
G TPO thyroid peroxidase increases expression EXP Silver Nitrate results in increased expression of TPO mRNA CTD PMID:27180073 NCBI chr 2:1,413,288...1,543,673
Ensembl chr 2:1,374,066...1,543,711
JBrowse link
sodium nitrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACADL acyl-CoA dehydrogenase long chain multiple interactions ISO sodium nitrate inhibits the reaction [Doxorubicin results in increased expression of ACADL protein] CTD PMID:21251210 NCBI chr 2:210,187,923...210,225,447
Ensembl chr 2:210,187,126...210,225,447
JBrowse link
G ACTC1 actin alpha cardiac muscle 1 multiple interactions ISO sodium nitrate inhibits the reaction [Doxorubicin results in increased expression of ACTC1 protein] CTD PMID:21251210 NCBI chr15:34,790,230...34,795,549
Ensembl chr15:34,790,230...34,795,549
JBrowse link
G AFP alpha fetoprotein multiple interactions ISO sodium nitrate inhibits the reaction [Doxorubicin results in decreased expression of AFP protein] CTD PMID:21251210 NCBI chr 4:73,436,221...73,456,174
Ensembl chr 4:73,431,138...73,456,174
JBrowse link
G ATP5F1B ATP synthase F1 subunit beta multiple interactions ISO sodium nitrate inhibits the reaction [Doxorubicin results in increased expression of ATP5B protein] CTD PMID:21251210 NCBI chr12:56,638,175...56,645,984
Ensembl chr12:56,638,175...56,645,984
JBrowse link
G ATP5PD ATP synthase peripheral stalk subunit d multiple interactions ISO sodium nitrate inhibits the reaction [Doxorubicin results in increased expression of ATP5H protein] CTD PMID:21251210 NCBI chr17:75,038,863...75,046,969
Ensembl chr17:75,038,863...75,046,985
JBrowse link
G CACNA2D1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 increases expression ISO sodium nitrate results in increased expression of CACNA2D1 protein CTD PMID:22687611 NCBI chr 7:81,946,444...82,443,956
Ensembl chr 7:81,946,444...82,443,777
JBrowse link
G CASQ1 calsequestrin 1 increases expression ISO sodium nitrate results in increased expression of CASQ1 protein CTD PMID:22687611 NCBI chr 1:160,190,575...160,201,886
Ensembl chr 1:160,190,575...160,201,886
JBrowse link
G CAT catalase decreases activity ISO sodium nitrate results in decreased activity of CAT protein CTD PMID:24740966 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
JBrowse link
G COX4I1 cytochrome c oxidase subunit 4I1 multiple interactions ISO sodium nitrate inhibits the reaction [Doxorubicin results in increased expression of COX4I1 protein] CTD PMID:21251210 NCBI chr16:85,799,695...85,807,068
Ensembl chr16:85,798,633...85,807,068
Ensembl chr16:85,798,633...85,807,068
JBrowse link
G CRYAB crystallin alpha B multiple interactions ISO sodium nitrate inhibits the reaction [Doxorubicin results in increased expression of CRYAB protein] CTD PMID:21251210 NCBI chr11:111,908,564...111,923,740
Ensembl chr11:111,908,564...111,923,722
JBrowse link
G FABP3 fatty acid binding protein 3 multiple interactions ISO sodium nitrate inhibits the reaction [Doxorubicin results in increased expression of FABP3 protein] CTD PMID:21251210 NCBI chr 1:31,359,595...31,373,618
Ensembl chr 1:31,365,253...31,376,850
JBrowse link
G FTH1 ferritin heavy chain 1 multiple interactions ISO sodium nitrate inhibits the reaction [Doxorubicin results in decreased expression of FTH1 protein] CTD PMID:21251210 NCBI chr11:61,964,285...61,967,634
Ensembl chr11:61,959,718...61,967,634
JBrowse link
G G6PD glucose-6-phosphate dehydrogenase decreases activity ISO sodium nitrate results in decreased activity of G6PD protein CTD PMID:19922758 NCBI chr  X:154,531,390...154,547,569
Ensembl chr  X:154,531,391...154,547,572
JBrowse link
G GOT1 glutamic-oxaloacetic transaminase 1 multiple interactions ISO sodium nitrate inhibits the reaction [Doxorubicin results in increased expression of GOT1 protein] CTD PMID:21251210 NCBI chr10:99,396,870...99,430,624
Ensembl chr10:99,396,870...99,430,624
JBrowse link
G GSR glutathione-disulfide reductase multiple interactions ISO [Quercetin co-treated with sodium nitrate] results in increased activity of GSR protein CTD PMID:24860958 NCBI chr 8:30,678,066...30,727,846
Ensembl chr 8:30,678,066...30,727,846
JBrowse link
G IDH3A isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha multiple interactions ISO sodium nitrate inhibits the reaction [Doxorubicin results in increased expression of IDH3A protein] CTD PMID:21251210 NCBI chr15:78,149,362...78,171,945
Ensembl chr15:78,131,498...78,171,945
JBrowse link
G LDHC lactate dehydrogenase C decreases activity ISO sodium nitrate results in decreased activity of LDHC protein CTD PMID:19922758 NCBI chr11:18,412,298...18,452,063
Ensembl chr11:18,412,318...18,452,063
JBrowse link
G MB myoglobin multiple interactions ISO sodium nitrate inhibits the reaction [Doxorubicin results in increased expression of MB protein] CTD PMID:21251210 NCBI chr22:35,606,764...35,623,354
Ensembl chr22:35,606,764...35,637,951
JBrowse link
G MPO myeloperoxidase multiple interactions ISO sodium nitrate inhibits the reaction [Diclofenac results in increased activity of MPO protein] CTD PMID:17275683 NCBI chr17:58,269,855...58,280,935
Ensembl chr17:58,269,855...58,280,935
JBrowse link
G MUC6 mucin 6, oligomeric mucus/gel-forming increases expression ISO sodium nitrate results in increased expression of MUC6 mRNA CTD PMID:17275683 NCBI chr11:1,012,823...1,036,718
Ensembl chr11:1,012,823...1,036,718
JBrowse link
G MYH6 myosin heavy chain 6 multiple interactions ISO sodium nitrate inhibits the reaction [Doxorubicin results in decreased expression of MYH6 protein] CTD PMID:21251210 NCBI chr14:23,381,987...23,408,273
Ensembl chr14:23,381,982...23,408,273
JBrowse link
G MYL2 myosin light chain 2 multiple interactions ISO [sodium nitrate co-treated with Doxorubicin] results in decreased expression of MYL2 protein; sodium nitrate inhibits the reaction [Doxorubicin results in increased expression of MYL2 protein] CTD PMID:21251210 NCBI chr12:110,910,845...110,920,579
Ensembl chr12:110,910,819...110,921,443
JBrowse link
G MYL3 myosin light chain 3 multiple interactions ISO sodium nitrate inhibits the reaction [Doxorubicin results in increased expression of MYL3 protein] CTD PMID:21251210 NCBI chr 3:46,857,872...46,863,444
Ensembl chr 3:46,835,111...46,882,172
JBrowse link
G MYOZ2 myozenin 2 multiple interactions ISO sodium nitrate inhibits the reaction [Doxorubicin results in increased expression of MYOZ2 protein] CTD PMID:21251210 NCBI chr 4:119,135,832...119,187,789
Ensembl chr 4:119,135,784...119,187,789
Ensembl chr 4:119,135,784...119,187,789
JBrowse link
G NOS2 nitric oxide synthase 2 multiple interactions ISO sodium nitrate inhibits the reaction [Diclofenac results in increased expression of NOS2 mRNA] CTD PMID:17275683 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529
JBrowse link
G NOS3 nitric oxide synthase 3 multiple interactions ISO sodium nitrate inhibits the reaction [NOS3 gene mutant form results in increased abundance of Triglycerides] CTD PMID:20876122 NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588
JBrowse link
G PKM pyruvate kinase M1/2 multiple interactions ISO sodium nitrate inhibits the reaction [Doxorubicin results in increased expression of PKM protein] CTD PMID:21251210 NCBI chr15:72,199,029...72,231,389
Ensembl chr15:72,199,029...72,231,822
JBrowse link
G PRDX3 peroxiredoxin 3 multiple interactions ISO sodium nitrate inhibits the reaction [Doxorubicin results in increased expression of PRDX3 protein] CTD PMID:21251210 NCBI chr10:119,167,720...119,178,812
Ensembl chr10:119,167,720...119,178,812
JBrowse link
G PRDX5 peroxiredoxin 5 increases expression
multiple interactions
ISO sodium nitrate results in increased expression of PRDX5 protein
sodium nitrate inhibits the reaction [Doxorubicin results in decreased expression of PRDX5 protein]
CTD PMID:21251210, PMID:22484629 NCBI chr11:64,318,121...64,321,811
Ensembl chr11:64,318,121...64,321,811
JBrowse link
G PYGB glycogen phosphorylase B multiple interactions ISO sodium nitrate inhibits the reaction [Doxorubicin results in decreased expression of PYGB protein] CTD PMID:21251210 NCBI chr20:25,248,039...25,298,012
Ensembl chr20:25,248,085...25,298,012
JBrowse link
G PYGM glycogen phosphorylase, muscle associated multiple interactions ISO sodium nitrate inhibits the reaction [Doxorubicin results in increased expression of PYGM protein] CTD PMID:21251210 NCBI chr11:64,746,389...64,760,715
Ensembl chr11:64,746,389...64,759,974
JBrowse link
G SOD2 superoxide dismutase 2 multiple interactions ISO sodium nitrate inhibits the reaction [Doxorubicin results in increased expression of SOD2 protein] CTD PMID:21251210 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529
Ensembl chr 6:159,669,069...159,762,529
Ensembl chr 6:159,669,069...159,762,529
JBrowse link
G SRL sarcalumenin multiple interactions ISO sodium nitrate inhibits the reaction [Doxorubicin results in increased expression of SRL protein] CTD PMID:21251210 NCBI chr16:4,189,374...4,242,253
Ensembl chr16:4,189,374...4,242,080
JBrowse link
G SUCLG2 succinate-CoA ligase GDP-forming subunit beta multiple interactions ISO sodium nitrate inhibits the reaction [Doxorubicin results in decreased expression of SUCLG2 protein] CTD PMID:21251210 NCBI chr 3:67,360,460...67,654,612
Ensembl chr 3:67,360,460...67,654,612
Ensembl chr 3:67,360,460...67,654,612
JBrowse link
G UQCRC1 ubiquinol-cytochrome c reductase core protein 1 multiple interactions ISO sodium nitrate inhibits the reaction [Doxorubicin results in increased expression of UQCRC1 protein] CTD PMID:21251210 NCBI chr 3:48,599,002...48,609,664
Ensembl chr 3:48,599,002...48,610,976
JBrowse link
G XDH xanthine dehydrogenase increases metabolic processing ISO XDH protein results in increased metabolism of sodium nitrate CTD PMID:20142047 NCBI chr 2:31,334,320...31,414,777
Ensembl chr 2:31,334,321...31,414,742
JBrowse link
G YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta multiple interactions ISO sodium nitrate inhibits the reaction [Doxorubicin results in decreased expression of YWHAZ protein] CTD PMID:21251210 NCBI chr 8:100,916,523...100,954,068
Ensembl chr 8:100,916,523...100,953,388
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 24359
    chemical entity 24327
      group 24209
        polyatomic entity 24209
          heteroatomic molecular entity 23798
            salt 15663
              nitrate salt 334
                inorganic nitrate salt + 334
                organic nitrate salt + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 24359
    subatomic particle 24315
      composite particle 24315
        hadron 24315
          baryon 24315
            nucleon 24315
              atomic nucleus 24315
                atom 24315
                  main group element atom 24160
                    p-block element atom 24160
                      chalcogen 23180
                        chalcogen molecular entity 23180
                          oxygen molecular entity 23052
                            oxide 12523
                              oxoanion 9155
                                pnictogen oxoanion 3709
                                  nitrogen oxoanion 347
                                    nitrate 334
                                      nitrate salt 334
                                        inorganic nitrate salt + 334
                                        organic nitrate salt + 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.