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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:organic halide salt
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Accession:CHEBI:51069 term browser browse the term
Synonyms:related_synonym: organic halide salts


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(1R,3S)-3-(adamantan-1-yl)-1-(aminomethyl)-3,4-dihydroisochromene-5,6-diol hydrochloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Drd1 dopamine receptor D1 multiple interactions
affects localization
ISO A 77636 binds to and results in increased activity of DRD1 protein; SCH 23390 inhibits the reaction [A 77636 affects the localization of DRD1 protein]; SCH 23390 inhibits the reaction [A 77636 results in increased activity of DRD1 protein] CTD PMID:15985612 NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002
JBrowse link
(S)-duloxetine hydrochloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor multiple interactions ISO Duloxetine Hydrochloride binds to and results in decreased activity of AR protein CTD PMID:25752796 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 decreases activity
multiple interactions
ISO Duloxetine Hydrochloride results in decreased activity of CYP17A1 protein
Duloxetine Hydrochloride inhibits the reaction [[CYP17A1 protein results in increased hydroxylation of Pregnenolone] which results in increased chemical synthesis of 17-alpha-Hydroxypregnenolone]; Duloxetine Hydrochloride inhibits the reaction [[CYP17A1 protein results in increased hydroxylation of Progesterone] which results in increased chemical synthesis of 17-alpha-Hydroxyprogesterone]; Duloxetine Hydrochloride inhibits the reaction [[CYP17A1 protein results in increased metabolism of 17-alpha-Hydroxypregnenolone] which results in increased chemical synthesis of Dehydroepiandrosterone]; Duloxetine Hydrochloride inhibits the reaction [[CYP17A1 protein results in increased metabolism of 17-alpha-Hydroxyprogesterone] which results in increased chemical synthesis of Androstenedione]; Duloxetine Hydrochloride inhibits the reaction [CYP17A1 protein results in increased hydroxylation of Pregnenolone]; Duloxetine Hydrochloride inhibits the reaction [CYP17A1 protein results in increased hydroxylation of Progesterone]; Duloxetine Hydrochloride inhibits the reaction [CYP17A1 protein results in increased metabolism of 17-alpha-Hydroxypregnenolone]; Duloxetine Hydrochloride inhibits the reaction [CYP17A1 protein results in increased metabolism of 17-alpha-Hydroxyprogesterone]
CTD PMID:29100959 NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions EXP [furafylline results in decreased activity of CYP1A2 protein] which results in decreased glutathionylation of Duloxetine Hydrochloride; CYP1A2 protein results in increased activity of and results in increased glutathionylation of Duloxetine Hydrochloride CTD PMID:20669986 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 multiple interactions EXP [Quinidine results in decreased activity of CYP2D6 protein] which results in decreased glutathionylation of Duloxetine Hydrochloride; CYP2D6 protein results in increased activity of and results in increased glutathionylation of Duloxetine Hydrochloride CTD PMID:20669986 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO Duloxetine Hydrochloride results in increased expression of HMOX1 mRNA CTD PMID:29134401 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO Duloxetine Hydrochloride results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008
JBrowse link
G Kcnj3 potassium inwardly-rectifying channel, subfamily J, member 3 multiple interactions ISO Duloxetine Hydrochloride results in decreased activity of [KCNJ3 mRNA co-treated with KCNJ5 mRNA]; Duloxetine Hydrochloride results in decreased activity of [KCNJ3 mRNA co-treated with KCNJ6 mRNA] CTD PMID:22164246 NCBI chr 3:39,944,896...40,106,646
Ensembl chr 3:39,945,351...40,109,124
JBrowse link
G Kcnj5 potassium inwardly-rectifying channel, subfamily J, member 5 multiple interactions ISO Duloxetine Hydrochloride results in decreased activity of [KCNJ3 mRNA co-treated with KCNJ5 mRNA] CTD PMID:22164246 NCBI chr 8:30,724,923...30,753,083
Ensembl chr 8:30,724,925...30,753,518
JBrowse link
G Kcnj6 potassium inwardly-rectifying channel, subfamily J, member 6 multiple interactions ISO Duloxetine Hydrochloride results in decreased activity of [KCNJ3 mRNA co-treated with KCNJ6 mRNA] CTD PMID:22164246 NCBI chr11:34,061,705...34,309,128
Ensembl chr11:34,061,708...34,308,758
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 affects localization ISO Duloxetine Hydrochloride affects the localization of NFE2L2 protein CTD PMID:29134401 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Prl prolactin increases expression ISO Duloxetine Hydrochloride results in increased expression of PRL protein CTD PMID:17606668 NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062
JBrowse link
1,1-dimethyl-4-phenylpiperazinium iodide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrna2 cholinergic receptor nicotinic alpha 2 subunit multiple interactions ISO
EXP
Dimethylphenylpiperazinium Iodide results in increased activity of [CHRNB4 protein binds to CHRNA2 protein]
1,1-dimethyl-4-phenylpiperazinium iodide affects binding competes with [Epibatidine binds to Chrna2 protein]
CTD PMID:9454827 PMID:15016836 RGD:2303194 NCBI chr15:40,342,317...40,358,601
Ensembl chr15:40,342,317...40,358,601
JBrowse link
G Chrna3 cholinergic receptor nicotinic alpha 3 subunit multiple interactions ISO
EXP
Dimethylphenylpiperazinium Iodide results in increased activity of [CHRNB4 protein binds to CHRNA3 protein]
1,1-dimethyl-4-phenylpiperazinium iodide affects binding [Epibatidine binds to Chrna3 protein]
CTD PMID:9454827 PMID:15016836 RGD:2303194 NCBI chr 8:55,401,981...55,415,012
Ensembl chr 8:55,401,702...55,415,165
JBrowse link
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit multiple interactions ISO
EXP
Dimethylphenylpiperazinium Iodide inhibits the reaction [epibatidine binds to [CHRNA4 protein binds to CHRNB2 protein]]; Dimethylphenylpiperazinium Iodide results in increased activity of [CHRNA4 protein binds to CHRNB2 protein]; Dimethylphenylpiperazinium Iodide results in increased activity of [CHRNB4 protein binds to CHRNA4 protein]
1,1-dimethyl-4-phenylpiperazinium iodide affects binding to Chrna4 protein; 1,1-dimethyl-4-phenylpiperazinium iodide competes with [Epibatidine binds to Chrna4 protein]
CTD PMID:9454827 PMID:14645658 PMID:15016836 RGD:2303194 NCBI chr 3:168,136,246...168,157,839
Ensembl chr 3:168,136,266...168,156,957
JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit multiple interactions
increases response to substance
increases activity
ISO Dimethylphenylpiperazinium Iodide inhibits the reaction [Bungarotoxins binds to CHRNA7 protein]
CHRNA7 protein mutant form results in increased susceptibility to Dimethylphenylpiperazinium Iodide
Dimethylphenylpiperazinium Iodide results in increased activity of CHRNA7 protein
CTD PMID:10082212 PMID:10216184 NCBI chr 1:116,715,286...116,837,223
Ensembl chr 1:116,714,711...116,837,240
JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit multiple interactions ISO
EXP
Dimethylphenylpiperazinium Iodide inhibits the reaction [epibatidine binds to [CHRNA4 protein binds to CHRNB2 protein]]; Dimethylphenylpiperazinium Iodide results in increased activity of [CHRNA4 protein binds to CHRNB2 protein]
1,1-dimethyl-4-phenylpiperazinium iodide affects binding to Chrnb2 protein; 1,1-dimethyl-4-phenylpiperazinium iodide competes with [Epibatidine binds to Chrnb2 protein]
CTD PMID:14645658 PMID:15016836 RGD:2303194 NCBI chr 2:175,181,402...175,189,619
Ensembl chr 2:175,181,402...175,189,619
JBrowse link
G Chrnb4 cholinergic receptor nicotinic beta 4 subunit multiple interactions ISO Dimethylphenylpiperazinium Iodide results in increased activity of [CHRNB4 protein binds to CHRNA2 protein]; Dimethylphenylpiperazinium Iodide results in increased activity of [CHRNB4 protein binds to CHRNA3 protein]; Dimethylphenylpiperazinium Iodide results in increased activity of [CHRNB4 protein binds to CHRNA4 protein] CTD PMID:9454827 NCBI chr 8:55,418,379...55,436,967
Ensembl chr 8:55,418,313...55,437,027
JBrowse link
G Tnf tumor necrosis factor increases activity EXP TNF results in increased activity of Dimethylphenylpiperazinium Iodide CTD PMID:15086448 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A decreases activity ISO thiazolyl blue results in decreased activity of ABCB1 protein CTD PMID:15451006 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Aco2 aconitase 2 multiple interactions ISO [Calcium results in increased activity of ACO2 protein] which results in increased reduction of thiazolyl blue; [Potassium deficiency results in decreased activity of ACO2 protein] which results in decreased reduction of thiazolyl blue CTD PMID:12548706 NCBI chr 7:113,385,677...113,428,794
Ensembl chr 7:113,385,646...113,428,261
JBrowse link
G Casp3 caspase 3 increases activity ISO thiazolyl blue results in increased activity of CASP3 protein CTD PMID:22401948 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp8 caspase 8 increases activity ISO thiazolyl blue results in increased activity of CASP8 protein CTD PMID:22401948 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Nqo2 N-ribosyldihydronicotinamide:quinone reductase 2 increases reduction
multiple interactions
ISO NQO2 protein results in increased reduction of thiazolyl blue
resveratrol inhibits the reaction [NQO2 protein results in increased reduction of thiazolyl blue]; Tacrine inhibits the reaction [NQO2 protein results in increased reduction of thiazolyl blue]
CTD PMID:29281794 NCBI chr17:30,909,482...30,938,725
Ensembl chr17:30,909,187...30,938,320
JBrowse link
4-fluoro-N-\{2-[4-(7-methoxynaphthalen-1-yl)piperazin-1-yl]ethyl\}benzamide hydrochloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Htr1a 5-hydroxytryptamine receptor 1A multiple interactions EXP [1-((4-fluorobenzoylamino)ethyl)-4-(7-methoxy-1-naphthyl)piperazine hydrochloride binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to 1-(3-chlorophenyl)piperazine; [1-((4-fluorobenzoylamino)ethyl)-4-(7-methoxy-1-naphthyl)piperazine hydrochloride binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to Apomorphine; [1-((4-fluorobenzoylamino)ethyl)-4-(7-methoxy-1-naphthyl)piperazine hydrochloride binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to Physostigmine; tertatolol inhibits the reaction [[1-((4-fluorobenzoylamino)ethyl)-4-(7-methoxy-1-naphthyl)piperazine hydrochloride binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to Apomorphine]; tertatolol inhibits the reaction [[1-((4-fluorobenzoylamino)ethyl)-4-(7-methoxy-1-naphthyl)piperazine hydrochloride binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to Physostigmine] CTD PMID:8539317 NCBI chr 2:36,694,174...36,695,442
Ensembl chr 2:36,694,174...36,695,442
JBrowse link
acridine orange term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator increases response to substance ISO BAX protein results in increased susceptibility to Acridine Orange CTD PMID:16177561 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions ISO [Acridine Orange binds to Platinum Compounds] which results in increased expression of GSTP1 mRNA; [Acridine Orange binds to Platinum] which results in increased expression of GSTP1 mRNA CTD PMID:16814760 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO Acridine Orange results in increased stability of and results in increased activity of TP53 protein CTD PMID:16177561 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
ambenonium chloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G App amyloid beta precursor protein affects cleavage EXP Ambenonium Chloride affects the cleavage of APP protein CTD PMID:11099780 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
amprolium term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc19a3 solute carrier family 19 member 3 multiple interactions ISO Amprolium inhibits the reaction [SLC19A3 protein results in increased uptake of Metformin]; Amprolium inhibits the reaction [SLC19A3 protein results in increased uptake of Thiamine] CTD PMID:26528626 NCBI chr 9:84,275,722...84,299,368
Ensembl chr 9:84,277,024...84,299,337
JBrowse link
atomoxetine hydrochloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 increases hydroxylation ISO CYP2D6 protein results in increased hydroxylation of Atomoxetine Hydrochloride CTD PMID:17470523 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759
JBrowse link
auramine O term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 multiple interactions
increases expression
ISO ALDH1A1 protein promotes the reaction [Benzophenoneidum results in increased lipidation of and results in increased cleavage of MAP1LC3B protein]
Benzophenoneidum results in increased expression of ALDH1A1 protein
CTD PMID:28722353 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
JBrowse link
G Ano6 anoctamin 6 increases expression ISO Benzophenoneidum results in increased expression of ANO6 protein CTD PMID:28722353 NCBI chr 7:126,933,629...127,113,589
Ensembl chr 7:126,933,936...127,113,589
JBrowse link
G Araf A-Raf proto-oncogene, serine/threonine kinase increases expression ISO Benzophenoneidum results in increased expression of ARAF protein CTD PMID:28722353 NCBI chr  X:1,227,392...1,292,356
Ensembl chr  X:1,227,392...1,239,073
JBrowse link
G Atp6ap2 ATPase H+ transporting accessory protein 2 increases expression ISO Benzophenoneidum results in increased expression of ATP6AP2 protein CTD PMID:28722353 NCBI chr  X:10,183,983...10,210,948
Ensembl chr  X:10,183,068...10,210,918
JBrowse link
G Ccdc22 coiled-coil domain containing 22 increases expression ISO Benzophenoneidum results in increased expression of CCDC22 protein CTD PMID:28722353 NCBI chr  X:14,898,296...14,910,244
Ensembl chr  X:14,898,296...14,910,244
JBrowse link
G Ccdc39 coiled-coil domain containing 39 increases expression ISO Benzophenoneidum results in increased expression of CCDC39 protein CTD PMID:28722353 NCBI chr 2:116,665,261...116,703,364
Ensembl chr 2:116,665,261...116,703,350
JBrowse link
G Cd44 CD44 molecule (Indian blood group) increases expression ISO Benzophenoneidum results in increased expression of CD44 protein CTD PMID:28722353 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620
JBrowse link
G Chtf18 chromosome transmission fidelity factor 18 increases expression ISO Benzophenoneidum results in increased expression of CHTF18 protein CTD PMID:28722353 NCBI chr10:14,743,006...14,751,044
Ensembl chr10:14,742,621...14,751,050
JBrowse link
G Commd1 copper metabolism domain containing 1 increases expression ISO Benzophenoneidum results in increased expression of COMMD1 protein CTD PMID:28722353 NCBI chr14:96,880,463...96,984,494
Ensembl chr14:96,880,463...96,984,501
JBrowse link
G Cops7b COP9 signalosome subunit 7B increases expression ISO Benzophenoneidum results in increased expression of COPS7B protein CTD PMID:28722353 NCBI chr 9:87,238,132...87,263,967
Ensembl chr 9:87,238,375...87,263,967
JBrowse link
G Cul3 cullin 3 increases expression ISO Benzophenoneidum results in increased expression of CUL3 protein CTD PMID:28722353 NCBI chr 9:81,592,641...81,670,428
Ensembl chr 9:81,592,641...81,670,462
JBrowse link
G Dynlt1 dynein light chain Tctex-type 1 increases expression ISO Benzophenoneidum results in increased expression of DYNLT1 protein CTD PMID:28722353 NCBI chr 1:46,887,017...46,893,956
Ensembl chr 1:46,887,017...46,893,881
JBrowse link
G Eif4g3 eukaryotic translation initiation factor 4 gamma, 3 increases expression ISO Benzophenoneidum results in increased expression of EIF4G3 protein CTD PMID:28722353 NCBI chr 5:150,197,410...150,418,363
Ensembl chr 5:150,195,226...150,418,363
JBrowse link
G Fastkd2 FAST kinase domains 2 increases expression ISO Benzophenoneidum results in increased expression of FASTKD2 protein CTD PMID:28722353 NCBI chr 9:65,166,148...65,188,184
Ensembl chr 9:65,168,228...65,188,174
JBrowse link
G Hook3 hook microtubule-tethering protein 3 increases expression ISO Benzophenoneidum results in increased expression of HOOK3 protein CTD PMID:28722353 NCBI chr16:65,954,293...66,058,812 JBrowse link
G Hsd17b7 hydroxysteroid (17-beta) dehydrogenase 7 increases expression ISO Benzophenoneidum results in increased expression of HSD17B7 protein CTD PMID:28722353 NCBI chr13:82,170,079...82,190,018
Ensembl chr13:82,173,179...82,190,017
JBrowse link
G Htt huntingtin increases expression ISO Benzophenoneidum results in increased expression of HTT protein CTD PMID:28722353 NCBI chr14:75,845,836...75,996,094
Ensembl chr14:75,845,836...75,995,070
JBrowse link
G Iqgap3 IQ motif containing GTPase activating protein 3 increases expression ISO Benzophenoneidum results in increased expression of IQGAP3 protein CTD PMID:28722353 NCBI chr 2:173,542,151...173,583,956
Ensembl chr 2:173,542,110...173,583,956
JBrowse link
G Kifap3 kinesin-associated protein 3 increases expression ISO Benzophenoneidum results in increased expression of KIFAP3 protein CTD PMID:28722353 NCBI chr13:76,127,702...76,264,654
Ensembl chr13:76,127,696...76,264,650
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta multiple interactions ISO ALDH1A1 protein promotes the reaction [Benzophenoneidum results in increased lipidation of and results in increased cleavage of MAP1LC3B protein]; Benzophenoneidum results in increased lipidation of and results in increased cleavage of MAP1LC3B protein CTD PMID:28722353 NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
JBrowse link
G Map2k4 mitogen activated protein kinase kinase 4 increases expression ISO Benzophenoneidum results in increased expression of MAP2K4 protein CTD PMID:28722353 NCBI chr10:50,343,227...50,447,956
Ensembl chr10:50,344,915...50,447,993
JBrowse link
G Mbd3 methyl-CpG binding domain protein 3 increases expression ISO Benzophenoneidum results in increased expression of MBD3 protein CTD PMID:28722353 NCBI chr 7:9,312,961...9,320,166
Ensembl chr 7:9,313,098...9,320,165
JBrowse link
G Noa1 nitric oxide associated 1 increases expression ISO Benzophenoneidum results in increased expression of NOA1 protein CTD PMID:28722353 NCBI chr14:30,835,012...30,851,296
Ensembl chr14:30,835,247...30,851,293
JBrowse link
G Nup62 nucleoporin 62 increases expression ISO Benzophenoneidum results in increased expression of NUP62 protein CTD PMID:28722353 NCBI chr 1:95,298,995...95,314,902
Ensembl chr 1:95,295,526...95,315,174
JBrowse link
G Plcg1 phospholipase C, gamma 1 increases expression ISO Benzophenoneidum results in increased expression of PLCG1 protein CTD PMID:28722353 NCBI chr 3:149,385,587...149,416,330
Ensembl chr 3:149,385,587...149,416,330
JBrowse link
G Ppp4r1 protein phosphatase 4, regulatory subunit 1 increases expression ISO Benzophenoneidum results in increased expression of PPP4R1 protein CTD PMID:28722353 NCBI chr 9:105,391,271...105,450,626
Ensembl chr 9:105,391,412...105,450,633
JBrowse link
G Prim2 DNA primase subunit 2 increases expression ISO Benzophenoneidum results in increased expression of PRIM2 protein CTD PMID:28722353 NCBI chr 9:35,692,376...35,904,521
Ensembl chr 9:35,692,376...35,903,030
JBrowse link
G Prom1 prominin 1 increases expression ISO Benzophenoneidum results in increased expression of PROM1 protein CTD PMID:28722353 NCBI chr14:66,989,545...67,094,534
Ensembl chr14:66,990,160...67,094,527
JBrowse link
G Prorp protein only RNase P catalytic subunit increases expression ISO Benzophenoneidum results in increased expression of PRORP protein CTD PMID:28722353 NCBI chr 6:72,669,659...72,762,419
Ensembl chr 6:72,670,847...72,762,416
JBrowse link
G Shmt1 serine hydroxymethyltransferase 1 increases expression ISO Benzophenoneidum results in increased expression of SHMT1 protein CTD PMID:28722353 NCBI chr10:45,468,698...45,497,820
Ensembl chr10:45,468,700...45,497,820
JBrowse link
G Srsf11 serine and arginine rich splicing factor 11 increases expression ISO Benzophenoneidum results in increased expression of SRSF11 protein CTD PMID:28722353 NCBI chr 2:247,074,623...247,101,460
Ensembl chr 2:247,074,631...247,101,425
JBrowse link
G Tbc1d15 TBC1 domain family, member 15 increases expression ISO Benzophenoneidum results in increased expression of TBC1D15 protein CTD PMID:28722353 NCBI chr 7:50,804,553...50,860,272
Ensembl chr 7:50,804,012...50,860,175
JBrowse link
G Tfam transcription factor A, mitochondrial increases expression ISO Benzophenoneidum results in increased expression of TFAM protein CTD PMID:28722353 NCBI chr20:17,356,243...17,368,293
Ensembl chr20:17,356,197...17,368,292
JBrowse link
G Usp24 ubiquitin specific peptidase 24 increases expression ISO Benzophenoneidum results in increased expression of USP24 protein CTD PMID:28722353 NCBI chr 5:121,080,687...121,210,321
Ensembl chr 5:121,080,470...121,210,311
JBrowse link
G Washc5 WASH complex subunit 5 increases expression ISO Benzophenoneidum results in increased expression of WASHC5 protein CTD PMID:28722353 NCBI chr 7:90,884,333...90,936,118
Ensembl chr 7:90,884,197...90,936,103
JBrowse link
azure A term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpt glutamic--pyruvic transaminase increases activity EXP Azure A results in increased activity of GPT protein CTD PMID:33775737 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
azure B term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G App amyloid beta precursor protein multiple interactions ISO [Azure B affects the cleavage of APP protein] which results in decreased secretion of APP protein modified form; Azure B results in decreased expression of and affects the cleavage of APP protein CTD PMID:30500345 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Bace1 beta-secretase 1 decreases activity ISO Azure B results in decreased activity of BACE1 protein CTD PMID:30500345 NCBI chr 8:46,142,060...46,166,268
Ensembl chr 8:46,142,116...46,165,876
JBrowse link
benzalkonium chloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aacs acetoacetyl-CoA synthetase increases expression ISO Benzalkonium Compounds results in increased expression of AACS mRNA CTD PMID:31199489 NCBI chr12:31,113,098...31,156,411
Ensembl chr12:31,113,098...31,160,954
JBrowse link
G Abca1 ATP binding cassette subfamily A member 1 decreases expression ISO Benzalkonium Compounds results in decreased expression of ABCA1 mRNA CTD PMID:26919959 NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
JBrowse link
G Abca12 ATP binding cassette subfamily A member 12 increases expression ISO Benzalkonium Compounds results in increased expression of ABCA12 mRNA CTD PMID:25377654 NCBI chr 9:72,822,661...72,995,748
Ensembl chr 9:72,823,350...72,996,049
JBrowse link
G Abca6 ATP binding cassette subfamily A member 6 decreases expression ISO Benzalkonium Compounds results in decreased expression of ABCA6 mRNA CTD PMID:20713136 NCBI chr10:95,142,805...95,212,087
Ensembl chr10:95,142,966...95,211,530
JBrowse link
G Acod1 aconitate decarboxylase 1 increases expression ISO Benzalkonium Compounds results in increased expression of ACOD1 mRNA CTD PMID:30171875 NCBI chr15:79,871,819...79,881,101
Ensembl chr15:79,871,827...79,880,529
JBrowse link
G Acp6 acid phosphatase 6, lysophosphatidic increases expression ISO Benzalkonium Compounds results in increased expression of ACP6 mRNA CTD PMID:31199489 NCBI chr 2:184,711,975...184,733,067
Ensembl chr 2:184,711,619...184,733,017
JBrowse link
G Acsl4 acyl-CoA synthetase long-chain family member 4 increases expression ISO Benzalkonium Compounds results in increased expression of ACSL4 mRNA CTD PMID:31199489 NCBI chr  X:105,942,794...106,006,573
Ensembl chr  X:105,942,799...106,006,427
JBrowse link
G Ada adenosine deaminase increases expression ISO Benzalkonium Compounds results in increased expression of ADA mRNA CTD PMID:30171875 NCBI chr 3:152,398,745...152,422,854
Ensembl chr 3:152,398,747...152,447,088
JBrowse link
G Adh1 alcohol dehydrogenase 1 (class I) decreases expression ISO Benzalkonium Compounds results in decreased expression of ADH1 mRNA CTD PMID:31199489 NCBI chr 2:226,797,303...226,808,892
Ensembl chr 2:226,797,303...226,808,892
JBrowse link
G Adora1 adenosine A1 receptor decreases expression ISO Benzalkonium Compounds results in decreased expression of ADORA1 mRNA CTD PMID:30171875 NCBI chr13:45,658,872...45,695,821
Ensembl chr13:45,658,872...45,695,801
JBrowse link
G Adra2a adrenoceptor alpha 2A multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of ADRA2A mRNA CTD PMID:30171875 NCBI chr 1:253,061,480...253,064,280
Ensembl chr 1:253,060,218...253,064,365
JBrowse link
G Agtr2 angiotensin II receptor, type 2 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of AGTR2 mRNA CTD PMID:30171875 NCBI chr  X:112,119,673...112,124,060
Ensembl chr  X:112,120,228...112,124,057
JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 increases expression ISO Benzalkonium Compounds results in increased expression of AKR1B10 mRNA CTD PMID:30806763 NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852
JBrowse link
G Alb albumin decreases expression ISO Benzalkonium Compounds results in decreased expression of ALB mRNA CTD PMID:31199489 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Apoa1 apolipoprotein A1 decreases expression ISO Benzalkonium Compounds results in decreased expression of APOA1 mRNA CTD PMID:31199489 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
JBrowse link
G Apoa2 apolipoprotein A2 decreases expression ISO Benzalkonium Compounds results in decreased expression of APOA2 mRNA CTD PMID:31199489 NCBI chr13:83,644,460...83,646,358
Ensembl chr13:83,644,470...83,646,355
JBrowse link
G Apoc1 apolipoprotein C1 decreases expression ISO Benzalkonium Compounds results in decreased expression of APOC1 mRNA CTD PMID:31199489 NCBI chr 1:79,347,057...79,350,340
Ensembl chr 1:79,346,136...79,350,375
JBrowse link
G Aqp3 aquaporin 3 (Gill blood group) increases expression ISO Benzalkonium Compounds results in increased expression of AQP3 mRNA CTD PMID:30171875 NCBI chr 5:56,239,200...56,244,718
Ensembl chr 5:56,239,201...56,244,720
JBrowse link
G Areg amphiregulin increases expression ISO Benzalkonium Compounds results in increased expression of AREG mRNA CTD PMID:30171875 NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535
JBrowse link
G Arg2 arginase 2 increases expression ISO Benzalkonium Compounds results in increased expression of ARG2 mRNA CTD PMID:30171875 NCBI chr 6:97,936,002...97,961,379
Ensembl chr 6:97,936,002...97,961,378
JBrowse link
G Art3 ADP-ribosyltransferase 3 decreases expression ISO Benzalkonium Compounds results in decreased expression of ART3 mRNA CTD PMID:31199489 NCBI chr14:15,637,230...15,719,442
Ensembl chr14:15,637,237...15,665,407
JBrowse link
G Atf4 activating transcription factor 4 decreases expression ISO Benzalkonium Compounds results in decreased expression of ATF4 mRNA CTD PMID:28236482 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
JBrowse link
G Atp5f1e ATP synthase F1 subunit epsilon decreases expression ISO Benzalkonium Compounds results in decreased expression of ATP5E mRNA CTD PMID:31199489 NCBI chr 3:163,259,072...163,261,974
Ensembl chr 3:163,260,476...163,261,450
JBrowse link
G Atp5mg ATP synthase membrane subunit g decreases expression ISO Benzalkonium Compounds results in decreased expression of ATP5L mRNA CTD PMID:31199489 NCBI chr 8:45,226,750...45,233,582
Ensembl chr 8:45,225,686...45,233,559
JBrowse link
G B3galt4 Beta-1,3-galactosyltransferase 4 affects response to substance ISO B3GALT4 SNP affects the susceptibility to Benzalkonium Compounds CTD PMID:27258892 NCBI chr20:4,936,089...4,937,664
Ensembl chr20:4,931,768...4,938,315
JBrowse link
G Bambi BMP and activin membrane-bound inhibitor increases expression ISO Benzalkonium Compounds results in increased expression of BAMBI mRNA CTD PMID:20146380 NCBI chr17:54,121,251...54,125,816
Ensembl chr17:54,121,255...54,126,060
JBrowse link
G Bcl3 BCL3, transcription coactivator increases expression ISO Benzalkonium Compounds results in increased expression of BCL3 mRNA CTD PMID:30171875 NCBI chr 1:79,471,368...79,485,908
Ensembl chr 1:79,471,369...79,485,607
JBrowse link
G Btc betacellulin decreases expression ISO Benzalkonium Compounds results in decreased expression of BTC mRNA CTD PMID:30171875 NCBI chr14:16,708,447...16,746,961
Ensembl chr14:16,707,982...16,747,049
JBrowse link
G C1s complement C1s multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of C1S2 mRNA CTD PMID:30171875 NCBI chr 4:157,430,249...157,442,438
Ensembl chr 4:157,430,117...157,442,303
JBrowse link
G C3 complement C3 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of C3 mRNA CTD PMID:30171875 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429
JBrowse link
G Casp3 caspase 3 increases cleavage
multiple interactions
ISO Benzalkonium Compounds analog results in increased cleavage of CASP3 protein
benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [Benzalkonium Compounds analog results in increased cleavage of CASP3 protein]
CTD PMID:31982400 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp8 caspase 8 decreases expression ISO Benzalkonium Compounds results in decreased expression of CASP8 mRNA CTD PMID:28236482 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Ccl11 C-C motif chemokine ligand 11 increases expression ISO Benzalkonium Compounds results in increased expression of CCL11 protein CTD PMID:30517752 NCBI chr10:67,028,328...67,032,929
Ensembl chr10:67,028,328...67,032,926
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression
increases secretion
ISO Benzalkonium Compounds results in increased expression of CCL2 mRNA; Benzalkonium Compounds results in increased expression of CCL2 protein
Benzalkonium Compounds results in increased secretion of CCL2 protein
CTD PMID:30171875 PMID:30517752 PMID:31707104 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl20 C-C motif chemokine ligand 20 increases expression ISO Benzalkonium Compounds results in increased expression of CCL20 mRNA CTD PMID:30806763 NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629
JBrowse link
G Ccl24 C-C motif chemokine ligand 24 decreases expression ISO Benzalkonium Compounds results in decreased expression of CCL24 mRNA CTD PMID:30171875 NCBI chr12:21,100,835...21,104,832
Ensembl chr12:21,100,835...21,104,893
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 increases expression
multiple interactions
ISO Benzalkonium Compounds results in increased expression of CCL3 protein
[IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in increased expression of CCL3 protein
CTD PMID:30517752 PMID:31158415 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
JBrowse link
G Ccl4 C-C motif chemokine ligand 4 decreases expression
multiple interactions
increases expression
ISO Benzalkonium Compounds results in decreased expression of CCL4 mRNA; Benzalkonium Compounds results in decreased expression of CCL4 protein
[IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in increased expression of CCL4 protein
Benzalkonium Compounds results in increased expression of CCL4 protein
CTD PMID:18353026 PMID:20713136 PMID:30517752 PMID:31158415 NCBI chr10:68,466,469...68,467,941
Ensembl chr10:68,452,052...68,468,231
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 increases expression ISO Benzalkonium Compounds results in increased expression of CCL5 protein CTD PMID:30517752 NCBI chr10:68,322,826...68,327,365
Ensembl chr10:68,322,829...68,327,377
JBrowse link
G Ccl7 C-C motif chemokine ligand 7 increases expression ISO Benzalkonium Compounds results in increased expression of CCL7 mRNA; Benzalkonium Compounds results in increased expression of CCL7 protein CTD PMID:30171875 PMID:30517752 NCBI chr10:67,016,446...67,018,296
Ensembl chr10:67,016,446...67,018,303
JBrowse link
G Ccn2 cellular communication network factor 2 decreases expression ISO Benzalkonium Compounds results in decreased expression of CCN2 mRNA CTD PMID:25377654 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734
JBrowse link
G Ccn3 cellular communication network factor 3 increases expression ISO Benzalkonium Compounds results in increased expression of CCN3 mRNA CTD PMID:30171875 NCBI chr 7:86,094,000...86,101,022
Ensembl chr 7:86,094,000...86,101,019
JBrowse link
G Ccr4 C-C motif chemokine receptor 4 decreases expression ISO Benzalkonium Compounds results in decreased expression of CCR4 mRNA CTD PMID:30171875 NCBI chr 8:114,176,256...114,182,155
Ensembl chr 8:114,176,974...114,178,056
JBrowse link
G Ccr5 C-C motif chemokine receptor 5 increases expression ISO Benzalkonium Compounds results in increased expression of CCR5 mRNA CTD PMID:30171875 NCBI chr 8:123,752,423...123,757,538
Ensembl chr 8:123,752,325...123,759,260
JBrowse link
G Cd177 CD177 molecule multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of CD177 mRNA CTD PMID:30171875 NCBI chr 1:80,340,034...80,360,599
Ensembl chr 1:80,340,034...80,360,621
JBrowse link
G Cd274 CD274 molecule multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of CD274 mRNA CTD PMID:30171875 NCBI chr 1:227,116,627...227,137,379
Ensembl chr 1:227,116,649...227,134,450
JBrowse link
G Cd300c2 CD300C molecule 2 increases expression ISO Benzalkonium Compounds results in increased expression of CD300C2 mRNA CTD PMID:30171875 NCBI chr10:100,253,312...100,258,553
Ensembl chr10:100,156,238...100,182,647
JBrowse link
G Cfap61 cilia and flagella associated protein 61 increases expression ISO Benzalkonium Compounds results in increased expression of CFAP61 mRNA CTD PMID:31199489 NCBI chr 3:133,354,400...133,633,310
Ensembl chr 3:133,354,197...133,633,320
JBrowse link
G Cfd complement factor D decreases expression ISO Benzalkonium Compounds results in decreased expression of CFD mRNA CTD PMID:30171875 NCBI chr 7:9,813,148...9,814,871
Ensembl chr 7:9,813,150...9,815,053
JBrowse link
G Chi3l1 chitinase 3 like 1 increases expression ISO Benzalkonium Compounds results in increased expression of CHIL1 mRNA CTD PMID:30171875 NCBI chr13:45,641,802...45,649,787
Ensembl chr13:45,641,802...45,649,787
JBrowse link
G Chrnb4 cholinergic receptor nicotinic beta 4 subunit decreases expression ISO Benzalkonium Compounds results in decreased expression of CHRNB4 mRNA CTD PMID:30171875 NCBI chr 8:55,418,379...55,436,967
Ensembl chr 8:55,418,313...55,437,027
JBrowse link
G Clcf1 cardiotrophin-like cytokine factor 1 increases expression ISO Benzalkonium Compounds results in increased expression of CLCF1 mRNA CTD PMID:30171875 NCBI chr 1:201,507,763...201,517,607
Ensembl chr 1:201,507,859...201,517,605
JBrowse link
G Cnfn cornifelin increases expression ISO Benzalkonium Compounds results in increased expression of CNFN mRNA; Benzalkonium Compounds results in increased expression of CNFN protein CTD PMID:25377654 NCBI chr 1:80,949,699...80,953,747
Ensembl chr 1:80,951,600...80,953,747
JBrowse link
G Csf1 colony stimulating factor 1 increases expression ISO Benzalkonium Compounds results in increased expression of CSF1 protein CTD PMID:30517752 NCBI chr 2:195,377,215...195,396,608
Ensembl chr 2:195,377,215...195,411,704
JBrowse link
G Csf2 colony stimulating factor 2 increases expression ISO Benzalkonium Compounds results in increased expression of CSF2 protein CTD PMID:30517752 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
JBrowse link
G Csf3 colony stimulating factor 3 increases expression ISO Benzalkonium Compounds results in increased expression of CSF3 protein CTD PMID:30517752 NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603
JBrowse link
G Ctps1 CTP synthase 1 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of CTPS mRNA CTD PMID:30171875 NCBI chr 5:134,125,022...134,154,155
Ensembl chr 5:134,125,025...134,154,180
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 increases expression
multiple interactions
ISO Benzalkonium Compounds results in increased expression of CXCL10 mRNA; Benzalkonium Compounds results in increased expression of CXCL10 protein
[IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in increased expression of CXCL10 protein
CTD PMID:23445166 PMID:30517752 PMID:31158415 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 increases expression
multiple interactions
ISO Benzalkonium Compounds results in increased expression of CXCL2 mRNA; Benzalkonium Compounds results in increased expression of CXCL2 protein
[IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in increased expression of CXCL2 protein
CTD PMID:30171875 PMID:30517752 PMID:31158415 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 multiple interactions
increases expression
ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of CXCL3 mRNA
Benzalkonium Compounds results in increased expression of CXCL1 protein; Benzalkonium Compounds results in increased expression of CXCL3 mRNA
CTD PMID:30171875 PMID:30517752 NCBI chr14:17,270,146...17,289,458
Ensembl chr14:17,270,146...17,289,511
JBrowse link
G Cxcl6 C-X-C motif chemokine ligand 6 multiple interactions
increases expression
ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of CXCL5 mRNA
Benzalkonium Compounds results in increased expression of CXCL5 mRNA; Benzalkonium Compounds results in increased expression of CXCL5 protein
CTD PMID:30171875 PMID:30517752 NCBI chr14:17,310,089...17,312,303
Ensembl chr14:17,310,426...17,313,093
JBrowse link
G Cxcr1 C-X-C motif chemokine receptor 1 increases expression ISO Benzalkonium Compounds results in increased expression of CXCR1 mRNA CTD PMID:30806763 NCBI chr 9:75,768,124...75,771,122
Ensembl chr 9:75,766,770...75,771,084
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 increases expression ISO Benzalkonium Compounds results in increased expression of CXCR4 mRNA CTD PMID:20713136 NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases expression
increases expression
ISO Benzalkonium Compounds results in decreased expression of CYP1A1 mRNA
Benzalkonium Compounds results in increased expression of CYP1A1 mRNA
CTD PMID:20713136 PMID:30806763 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 decreases expression ISO Benzalkonium Compounds results in decreased expression of CYP27A1 mRNA CTD PMID:20713136 NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551
JBrowse link
G Cyp51 cytochrome P450, family 51 increases expression ISO Benzalkonium Compounds results in increased expression of CYP51 mRNA CTD PMID:31199489 NCBI chr 4:30,036,956...30,055,410
Ensembl chr 4:30,036,865...30,055,410
JBrowse link
G Dhcr24 24-dehydrocholesterol reductase increases expression ISO Benzalkonium Compounds results in increased expression of DHCR24 mRNA CTD PMID:31199489 NCBI chr 5:121,344,637...121,368,853
Ensembl chr 5:121,344,575...121,371,137
JBrowse link
G Dhcr7 7-dehydrocholesterol reductase decreases activity
increases expression
ISO Benzalkonium Compounds results in decreased activity of DHCR7 protein
Benzalkonium Compounds results in increased expression of DHCR7 mRNA
CTD PMID:26919959 NCBI chr 1:199,015,081...199,031,055
Ensembl chr 1:199,015,081...199,031,055
JBrowse link
G Dio1 iodothyronine deiodinase 1 decreases activity ISO Benzalkonium Compounds results in decreased activity of DIO1 protein CTD PMID:30561685 NCBI chr 5:122,074,285...122,090,983
Ensembl chr 5:122,074,279...122,090,970
JBrowse link
G Dio2 iodothyronine deiodinase 2 decreases activity ISO Benzalkonium Compounds results in decreased activity of DIO2 protein CTD PMID:30561685 NCBI chr 6:109,665,523...109,679,809
Ensembl chr 6:109,665,523...109,679,809
JBrowse link
G Dio3 iodothyronine deiodinase 3 decreases activity ISO Benzalkonium Compounds results in decreased activity of DIO3 protein CTD PMID:30561685 NCBI chr 6:129,285,747...129,287,608
Ensembl chr 6:129,285,749...129,286,660
JBrowse link
G Dlk1 delta like non-canonical Notch ligand 1 decreases expression ISO Benzalkonium Compounds results in decreased expression of DLK1 mRNA CTD PMID:31199489 NCBI chr 6:128,410,216...128,417,518
Ensembl chr 6:128,410,316...128,417,522
JBrowse link
G Dusp1 dual specificity phosphatase 1 increases expression ISO Benzalkonium Compounds results in increased expression of DUSP1 mRNA CTD PMID:30806763 NCBI chr10:16,680,489...16,683,276 JBrowse link
G Ebp EBP, cholestenol delta-isomerase increases expression ISO Benzalkonium Compounds results in increased expression of EBP mRNA CTD PMID:26919959 NCBI chr  X:14,299,427...14,305,826
Ensembl chr  X:14,299,448...14,305,826
JBrowse link
G Egf epidermal growth factor decreases expression ISO Benzalkonium Compounds results in decreased expression of EGF mRNA CTD PMID:30171875 NCBI chr 2:218,219,408...218,302,370
Ensembl chr 2:218,219,415...218,302,064
JBrowse link
G Egr1 early growth response 1 increases expression ISO Benzalkonium Compounds results in increased expression of EGR1 mRNA CTD PMID:25377654 NCBI chr18:26,463,333...26,465,531
Ensembl chr18:26,462,981...26,466,766
JBrowse link
G Elf3 E74 like ETS transcription factor 3 increases expression ISO Benzalkonium Compounds results in increased expression of ELF3 mRNA CTD PMID:30171875 NCBI chr13:46,690,460...46,695,394
Ensembl chr13:46,690,466...46,695,481
JBrowse link
G Elovl1 ELOVL fatty acid elongase 1 increases expression ISO Benzalkonium Compounds results in increased expression of ELOVL1 mRNA CTD PMID:29155129 NCBI chr 5:131,961,478...131,965,961
Ensembl chr 5:131,961,322...131,965,958
JBrowse link
G Elovl6 ELOVL fatty acid elongase 6 increases expression ISO Benzalkonium Compounds results in increased expression of ELOVL6 mRNA CTD PMID:31199489 NCBI chr 2:218,063,682...218,174,767
Ensembl chr 2:218,063,804...218,171,186
JBrowse link
G Endou endonuclease, poly(U)-specific increases expression ISO Benzalkonium Compounds results in increased expression of ENDOU mRNA CTD PMID:30171875 NCBI chr 7:128,845,862...128,866,542
Ensembl chr 7:128,844,862...128,866,596
JBrowse link
G Eno1 enolase 1 decreases expression ISO Benzalkonium Compounds results in decreased expression of ENO1 mRNA CTD PMID:31199489 NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336
JBrowse link
G Etnk1 ethanolamine kinase 1 increases expression ISO Benzalkonium Compounds results in increased expression of ETNK1 mRNA CTD PMID:31199489 NCBI chr 4:176,126,056...176,170,325
Ensembl chr 4:176,126,180...176,193,770
JBrowse link
G Exo1 exonuclease 1 increases expression ISO Benzalkonium Compounds results in increased expression of EXO1 mRNA CTD PMID:30171875 NCBI chr13:87,809,725...87,834,654
Ensembl chr13:87,809,810...87,834,654
JBrowse link
G Ezr ezrin increases expression ISO Benzalkonium Compounds results in increased expression of EZR mRNA; Benzalkonium Compounds results in increased expression of EZR protein CTD PMID:29893927 NCBI chr 1:46,967,961...47,011,505
Ensembl chr 1:46,967,658...47,011,505
JBrowse link
G Fam83a family with sequence similarity 83, member A increases expression ISO Benzalkonium Compounds results in increased expression of FAM83A mRNA CTD PMID:30171875 NCBI chr 7:89,522,826...89,547,284
Ensembl chr 7:89,522,826...89,547,388
JBrowse link
G Fgf2 fibroblast growth factor 2 affects response to substance ISO FGF2 SNP affects the susceptibility to Benzalkonium Compounds CTD PMID:27206134 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221
JBrowse link
G Fgr FGR proto-oncogene, Src family tyrosine kinase increases expression ISO Benzalkonium Compounds results in increased expression of FGR mRNA CTD PMID:30171875 NCBI chr 5:145,189,814...145,219,571
Ensembl chr 5:145,189,841...145,217,326
JBrowse link
G Flg filaggrin increases expression ISO Benzalkonium Compounds results in increased expression of FLG mRNA CTD PMID:30171875 NCBI chr 2:178,888,688...178,912,731 JBrowse link
G Foxc1 forkhead box C1 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of FOXC1 mRNA CTD PMID:30171875 NCBI chr17:32,631,379...32,635,361
Ensembl chr17:32,633,142...32,634,803
JBrowse link
G Foxn1 forkhead box N1 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of FOXN1 mRNA CTD PMID:30171875 NCBI chr10:63,251,400...63,273,710
Ensembl chr10:63,251,400...63,273,710
JBrowse link
G Foxp3 forkhead box P3 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of FOXP3 mRNA CTD PMID:30171875 NCBI chr  X:14,908,494...14,924,994
Ensembl chr  X:14,908,494...14,923,838
JBrowse link
G Gata3 GATA binding protein 3 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of GATA3 mRNA CTD PMID:30171875 NCBI chr17:68,643,760...68,666,000
Ensembl chr17:68,643,873...68,665,391
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression ISO Benzalkonium Compounds results in increased expression of GCLC mRNA CTD PMID:30806763 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO Benzalkonium Compounds results in increased expression of GCLM mRNA CTD PMID:30806763 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
JBrowse link
G Gpx2 glutathione peroxidase 2 increases expression ISO Benzalkonium Compounds results in increased expression of GPX2 mRNA CTD PMID:30171875 NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877
JBrowse link
G Hbegf heparin-binding EGF-like growth factor increases expression ISO Benzalkonium Compounds results in increased expression of HBEGF mRNA CTD PMID:30171875 NCBI chr18:28,106,284...28,116,167
Ensembl chr18:28,105,760...28,116,441
JBrowse link
G Hck HCK proto-oncogene, Src family tyrosine kinase multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of HCK mRNA CTD PMID:30171875 NCBI chr 3:141,571,587...141,614,696
Ensembl chr 3:141,571,587...141,614,693
JBrowse link
G Hgf hepatocyte growth factor multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of HGF mRNA CTD PMID:30171875 NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha increases expression ISO Benzalkonium Compounds results in increased expression of HIF1A mRNA CTD PMID:30171875 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase increases expression ISO Benzalkonium Compounds results in increased expression of HMGCR mRNA CTD PMID:26919959 PMID:31199489 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 increases expression ISO Benzalkonium Compounds results in increased expression of HMGCS2 mRNA CTD PMID:31199489 NCBI chr 2:185,875,609...185,903,505
Ensembl chr 2:185,875,616...185,902,130
JBrowse link
G Hoxa7 homeobox A7 decreases expression ISO Benzalkonium Compounds results in decreased expression of HOXA7 mRNA CTD PMID:30171875 NCBI chr 4:81,315,730...81,317,629
Ensembl chr 4:81,314,625...81,317,659
JBrowse link
G Hsd17b7 hydroxysteroid (17-beta) dehydrogenase 7 increases expression ISO Benzalkonium Compounds results in increased expression of HSD17B7 mRNA CTD PMID:31199489 NCBI chr13:82,170,079...82,190,018
Ensembl chr13:82,173,179...82,190,017
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 decreases expression ISO Benzalkonium Compounds results in decreased expression of HSPA5 mRNA CTD PMID:28236482 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
JBrowse link
G Icam1 intercellular adhesion molecule 1 increases expression ISO Benzalkonium Compounds results in increased expression of ICAM1 mRNA; Benzalkonium Compounds results in increased expression of ICAM1 protein CTD PMID:21742781 PMID:30806763 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Idi1 isopentenyl-diphosphate delta isomerase 1 increases expression ISO Benzalkonium Compounds results in increased expression of IDI1 mRNA CTD PMID:31199489 NCBI chr17:61,629,592...61,637,357
Ensembl chr17:61,629,594...61,637,357
JBrowse link
G Ifng interferon gamma increases expression ISO Benzalkonium Compounds results in increased expression of IFNG protein CTD PMID:30517752 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Il10 interleukin 10 multiple interactions
increases expression
ISO Benzalkonium Compounds results in increased expression of and results in decreased secretion of IL10 protein
[IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in decreased expression of IL10 protein
Benzalkonium Compounds results in increased expression of IL10 protein
CTD PMID:29953848 PMID:30517752 PMID:31158415 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il13ra2 interleukin 13 receptor subunit alpha 2 increases expression ISO Benzalkonium Compounds results in increased expression of IL13RA2 mRNA CTD PMID:30171875 NCBI chr  X:111,002,590...111,074,053
Ensembl chr  X:111,002,592...111,072,381
JBrowse link
G Il15 interleukin 15 increases expression ISO Benzalkonium Compounds results in increased expression of IL15 protein CTD PMID:30517752 NCBI chr19:25,640,013...25,706,818
Ensembl chr19:25,640,251...25,706,820
JBrowse link
G Il17f interleukin 17F increases expression ISO Benzalkonium Compounds results in increased expression of IL17F mRNA CTD PMID:23445166 NCBI chr 9:23,190,094...23,201,482
Ensembl chr 9:23,190,100...23,201,482
JBrowse link
G Il18 interleukin 18 increases expression ISO Benzalkonium Compounds results in increased expression of IL18 protein
Benzalkonium Compounds results in increased expression of IL18 mRNA
CTD PMID:30517752 PMID:30806763 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
JBrowse link
G Il1a interleukin 1 alpha increases secretion
multiple interactions
increases expression
ISO Benzalkonium Compounds results in increased secretion of IL1A protein
[IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in increased expression of IL1A protein
Benzalkonium Compounds results in increased expression of IL1A protein
Benzalkonium Compounds results in increased expression of IL1A mRNA; Benzalkonium Compounds results in increased expression of IL1A protein
CTD PMID:8006454 PMID:12781210 PMID:25290854 PMID:30240708 PMID:30517752 More... NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Il1b interleukin 1 beta increases expression
multiple interactions
ISO Benzalkonium Compounds results in increased expression of IL1B protein
[IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in increased expression of IL1B protein
CTD PMID:29953848 PMID:30517752 PMID:31158415 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il1f10 interleukin 1 family member 10 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of IL1F10 mRNA CTD PMID:30171875 NCBI chr 3:7,072,511...7,075,439
Ensembl chr 3:7,072,511...7,075,439
JBrowse link
G Il23a interleukin 23 subunit alpha increases expression ISO Benzalkonium Compounds results in increased expression of IL23A mRNA CTD PMID:30171875 NCBI chr 7:721,809...723,923
Ensembl chr 7:721,809...723,923
JBrowse link
G Il27 interleukin 27 increases expression ISO Benzalkonium Compounds results in increased expression of IL27 protein CTD PMID:30517752 NCBI chr 1:181,173,108...181,178,720
Ensembl chr 1:181,173,372...181,178,582
JBrowse link
G Il3 interleukin 3 increases expression ISO Benzalkonium Compounds results in increased expression of IL3 protein CTD PMID:30517752 NCBI chr10:38,405,716...38,408,066
Ensembl chr10:38,405,716...38,408,066
JBrowse link
G Il31 interleukin 31 increases expression ISO Benzalkonium Compounds results in increased expression of IL31 protein CTD PMID:30517752 NCBI chr12:33,095,108...33,105,026 JBrowse link
G Il31ra interleukin 31 receptor A decreases expression ISO Benzalkonium Compounds results in decreased expression of IL31RA mRNA CTD PMID:30171875 NCBI chr 2:44,118,748...44,189,943
Ensembl chr 2:44,122,624...44,183,767
JBrowse link
G Il34 interleukin 34 decreases expression ISO Benzalkonium Compounds results in decreased expression of IL34 mRNA CTD PMID:30171875 NCBI chr19:38,714,990...38,782,749
Ensembl chr19:38,714,991...38,764,000
JBrowse link
G Il36a interleukin 36, alpha increases expression ISO Benzalkonium Compounds results in increased expression of IL36A mRNA CTD PMID:30171875 NCBI chr 3:6,996,851...7,001,400
Ensembl chr 3:6,996,851...7,001,400
JBrowse link
G Il36b interleukin 36, beta increases expression ISO Benzalkonium Compounds results in increased expression of IL36B mRNA CTD PMID:30171875 NCBI chr 3:7,024,862...7,122,489
Ensembl chr 3:7,021,973...7,031,619
JBrowse link
G Il36g interleukin 36, gamma increases expression ISO Benzalkonium Compounds results in increased expression of IL36G mRNA CTD PMID:30171875 NCBI chr 3:6,948,323...6,954,485
Ensembl chr 3:6,948,297...6,954,480
JBrowse link
G Il4 interleukin 4 increases expression
multiple interactions
ISO Benzalkonium Compounds results in increased expression of IL4 protein
[IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in decreased expression of IL4 protein
CTD PMID:30517752 PMID:31158415 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Il5 interleukin 5 increases expression ISO Benzalkonium Compounds results in increased expression of IL5 protein CTD PMID:30517752 NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213
JBrowse link
G Il6 interleukin 6 increases secretion
multiple interactions
affects response to substance
increases expression
ISO Benzalkonium Compounds results in increased secretion of IL6 protein
[IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of ADRA2A mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of AGTR2 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of C1S2 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of C3 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of CD177 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of CD274 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of CTPS mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of CXCL3 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of CXCL5 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of FOXC1 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of FOXN1 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of FOXP3 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of GATA3 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of GSDMA3 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of HCK mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of HGF mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of IGHA mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of IL1F10 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of KRT2 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of KRTAP14 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of KRTAP16-3 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of KRTAP19-2 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of KRTAP19-5 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of KRTAP19-9B mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of KRTAP6-1 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of KRTAP6-2 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of LTB mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of MMP25 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of MMP9 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of MRGPRA2B mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of MSX2 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of MYLK3 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of NRG2 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of PDCD1 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of PROKR2 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of PTX3 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of REG1 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of REG3G mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of RYR1 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of SAA3 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of SERPINB13 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of SIGLECE mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of SOX21 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of SRMS mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of ST14 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of TFAP2B mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of TNFRSF13C mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of TNFRSF26 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of TNFSF8 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of TSLP mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of VTCN1 mRNA; [IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in increased expression of IL6 protein
Benzalkonium Compounds results in increased expression of IL6 mRNA; Benzalkonium Compounds results in increased expression of IL6 protein
Benzalkonium Compounds results in increased expression of and results in increased secretion of IL6 protein
CTD PMID:17763283 PMID:28214551 PMID:29953848 PMID:30171875 PMID:30517752 More... NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Il6r interleukin 6 receptor multiple interactions
increases response to substance
ISO [IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in decreased expression of IL10 protein; [IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in decreased expression of IL4 protein; [IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in increased expression of CCL3 protein; [IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in increased expression of CCL4 protein; [IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in increased expression of CXCL10 protein; [IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in increased expression of CXCL2 protein; [IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in increased expression of IL1A protein; [IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in increased expression of IL1B protein; [IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in increased expression of IL22 protein; [IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in increased expression of IL6 protein CTD PMID:31158415 NCBI chr 2:175,289,157...175,347,719
Ensembl chr 2:175,298,686...175,347,536
JBrowse link
G Il7r interleukin 7 receptor increases expression ISO Benzalkonium Compounds results in increased expression of IL7R mRNA CTD PMID:20713136 NCBI chr 2:58,452,393...58,477,757
Ensembl chr 2:58,454,217...58,477,757
JBrowse link
G Inhba inhibin subunit beta A increases expression ISO Benzalkonium Compounds results in increased expression of INHBA mRNA CTD PMID:30171875 NCBI chr17:49,091,635...49,111,573
Ensembl chr17:49,095,920...49,108,982
JBrowse link
G Insig1 insulin induced gene 1 increases expression ISO Benzalkonium Compounds results in increased expression of INSIG1 mRNA CTD PMID:31199489 NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952
JBrowse link
G Isl1 ISL LIM homeobox 1 decreases expression ISO Benzalkonium Compounds results in decreased expression of ISL1 mRNA CTD PMID:30171875 NCBI chr 2:48,079,412...48,090,704
Ensembl chr 2:48,080,522...48,095,584
JBrowse link
G Iyd iodotyrosine deiodinase multiple interactions ISO Benzalkonium Compounds inhibits the reaction [IYD protein results in increased metabolism of Monoiodotyrosine] CTD PMID:33352258 NCBI chr 1:40,003,999...40,019,323
Ensembl chr 1:40,004,041...40,019,319
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO Benzalkonium Compounds results in decreased activity of KCNH2 protein CTD PMID:24052561 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008
JBrowse link
G Kdm8 lysine demethylase 8 decreases expression ISO Benzalkonium Compounds results in decreased expression of KDM8 mRNA CTD PMID:31199489 NCBI chr 1:180,013,969...180,028,829
Ensembl chr 1:180,020,656...180,028,841
JBrowse link
G Klk8 kallikrein related-peptidase 8 increases expression ISO Benzalkonium Compounds results in increased expression of KLK8 mRNA CTD PMID:30171875 NCBI chr 1:94,251,803...94,258,646
Ensembl chr 1:94,251,803...94,258,646
JBrowse link
G Krt2 keratin 2 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of KRT2 mRNA CTD PMID:30171875 NCBI chr 7:132,941,275...132,947,963
Ensembl chr 7:132,940,862...132,947,963
JBrowse link
G Krtap14 keratin associated protein 14 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of KRTAP14 mRNA CTD PMID:30171875 NCBI chr11:28,126,660...28,127,502
Ensembl chr11:28,126,660...28,127,502
JBrowse link
G Lce3e late cornified envelope 3E increases expression ISO Benzalkonium Compounds results in increased expression of LCE3C mRNA CTD PMID:30171875 NCBI chr 2:178,579,162...178,579,458 JBrowse link
G Ldha lactate dehydrogenase A decreases expression ISO Benzalkonium Compounds results in decreased expression of LDHA mRNA CTD PMID:31199489 NCBI chr 1:97,371,823...97,381,247
Ensembl chr 1:97,366,021...97,433,472
JBrowse link
G Ldlr low density lipoprotein receptor increases expression ISO Benzalkonium Compounds results in increased expression of LDLR mRNA CTD PMID:31199489 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
JBrowse link
G Lif LIF, interleukin 6 family cytokine increases expression ISO Benzalkonium Compounds results in increased expression of LIF protein CTD PMID:30517752 NCBI chr14:79,131,049...79,140,486
Ensembl chr14:79,134,574...79,140,482
JBrowse link
G LOC102551406 keratin-associated protein 20-2-like multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of KRTAP6-1 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of KRTAP6-2 mRNA CTD PMID:30171875 NCBI chr11:28,412,307...28,412,508
Ensembl chr11:28,481,578...28,481,748
JBrowse link
G LOC102552326 late cornified envelope protein 5A-like decreases expression ISO Benzalkonium Compounds results in decreased expression of LCE1M mRNA CTD PMID:30171875 Ensembl chr 2:178,275,020...178,275,469 JBrowse link
G Loxl1 lysyl oxidase-like 1 decreases expression ISO Benzalkonium Compounds results in decreased expression of LOXL1 mRNA CTD PMID:31199489 NCBI chr 8:58,692,592...58,716,356
Ensembl chr 8:58,692,593...58,716,356
JBrowse link
G Lst1 leukocyte specific transcript 1 increases expression ISO Benzalkonium Compounds results in increased expression of LST1 mRNA CTD PMID:30171875 NCBI chr20:3,634,680...3,639,731
Ensembl chr20:3,634,749...3,637,997
JBrowse link
G Ltb lymphotoxin beta multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of LTB mRNA CTD PMID:30171875 NCBI chr20:3,627,536...3,629,381
Ensembl chr20:3,627,537...3,629,381
JBrowse link
G Mapk14 mitogen activated protein kinase 14 increases phosphorylation ISO Benzalkonium Compounds results in increased phosphorylation of MAPK14 protein CTD PMID:15737199 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
JBrowse link
G Mesp2 mesoderm posterior bHLH transcription factor 2 decreases expression ISO Benzalkonium Compounds results in decreased expression of MESP2 mRNA CTD PMID:30171875 NCBI chr 1:133,756,601...133,759,207
Ensembl chr 1:133,756,601...133,759,198
JBrowse link
G Mif macrophage migration inhibitory factor increases secretion ISO Benzalkonium Compounds results in increased secretion of MIF protein CTD PMID:31707104 NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504
JBrowse link
G Mmp10 matrix metallopeptidase 10 increases expression ISO Benzalkonium Compounds results in increased expression of MMP10 mRNA CTD PMID:30806763 NCBI chr 8:4,689,840...4,697,748
Ensembl chr 8:4,689,840...4,697,748
JBrowse link
G Mmp12 matrix metallopeptidase 12 increases expression ISO Benzalkonium Compounds results in increased expression of MMP12 mRNA CTD PMID:30171875 NCBI chr 8:4,581,785...4,591,687
Ensembl chr 8:4,581,785...4,599,611
JBrowse link
G Mmp25 matrix metallopeptidase 25 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of MMP25 mRNA CTD PMID:30171875 NCBI chr10:12,661,297...12,676,119 JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of MMP9 mRNA CTD PMID:30171875 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Msmo1 methylsterol monooxygenase 1 increases expression ISO Benzalkonium Compounds results in increased expression of MSMO1 mRNA CTD PMID:31199489 NCBI chr16:24,980,680...24,997,927
Ensembl chr16:24,980,697...24,998,016
JBrowse link
G Msx2 msh homeobox 2 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of MSX2 mRNA CTD PMID:30171875 NCBI chr17:11,097,214...11,102,879
Ensembl chr17:11,097,103...11,102,879
JBrowse link
G Mt2A metallothionein 2A decreases expression ISO Benzalkonium Compounds results in decreased expression of MT2 mRNA CTD PMID:31199489 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
JBrowse link
G Mthfd2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase decreases expression ISO Benzalkonium Compounds results in decreased expression of MTHFD2 mRNA CTD PMID:31199489 NCBI chr 4:115,811,135...115,822,663
Ensembl chr 4:115,811,139...115,822,608
JBrowse link
G Mylk3 myosin light chain kinase 3 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of MYLK3 mRNA CTD PMID:30171875 NCBI chr19:21,685,085...21,743,587
Ensembl chr19:21,691,929...21,742,954
JBrowse link
G Ndufa4 NDUFA4, mitochondrial complex associated decreases expression ISO Benzalkonium Compounds results in decreased expression of NDUFA4 mRNA CTD PMID:31199489 NCBI chr 4:40,002,216...40,009,384
Ensembl chr 4:40,002,216...40,023,920
JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 increases expression ISO Benzalkonium Compounds results in increased expression of NR4A2 mRNA CTD PMID:25377654 NCBI chr 3:41,689,847...41,707,036
Ensembl chr 3:41,689,851...41,697,877
JBrowse link
G Nrg2 neuregulin 2 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of NRG2 mRNA CTD PMID:30171875 NCBI chr18:27,619,635...27,798,505
Ensembl chr18:27,619,661...27,798,505
JBrowse link
G Ntrk3 neurotrophic receptor tyrosine kinase 3 affects response to substance ISO NTRK3 SNP affects the susceptibility to Benzalkonium Compounds CTD PMID:27206134 NCBI chr 1:132,116,472...132,503,849
Ensembl chr 1:132,132,849...132,503,286
JBrowse link
G Ocln occludin decreases expression ISO Benzalkonium Compounds results in decreased expression of OCLN protein CTD PMID:29514330 NCBI chr 2:31,657,217...31,707,466
Ensembl chr 2:31,657,220...31,764,150
JBrowse link
G Odc1 ornithine decarboxylase 1 decreases expression ISO Benzalkonium Compounds results in decreased expression of ODC1 mRNA CTD PMID:31199489 NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440
JBrowse link
G Odf3l2 outer dense fiber of sperm tails 3-like 2 decreases expression ISO Benzalkonium Compounds results in decreased expression of ODF3L2 mRNA CTD PMID:30171875 NCBI chr 7:10,049,472...10,065,626
Ensembl chr 7:10,059,589...10,065,125
JBrowse link
G Olr1 oxidized low density lipoprotein receptor 1 increases expression ISO Benzalkonium Compounds results in increased expression of OLR1 mRNA CTD PMID:30171875 NCBI chr 4:162,926,436...162,949,057
Ensembl chr 4:162,926,439...162,948,523
JBrowse link
G Orm1 orosomucoid 1 decreases expression ISO Benzalkonium Compounds results in decreased expression of ORM1 mRNA CTD PMID:30171875 NCBI chr 5:76,766,637...76,776,149
Ensembl chr 5:76,772,941...76,776,154
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage
multiple interactions
ISO Benzalkonium Compounds analog results in increased cleavage of PARP1 protein
benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [Benzalkonium Compounds analog results in increased cleavage of PARP1 protein]
CTD PMID:31982400 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pbk PDZ binding kinase increases expression ISO Benzalkonium Compounds results in increased expression of PBK mRNA CTD PMID:30171875 NCBI chr15:40,022,873...40,034,014
Ensembl chr15:40,023,002...40,034,014
JBrowse link
G Pcsk9 proprotein convertase subtilisin/kexin type 9 decreases expression ISO Benzalkonium Compounds results in decreased expression of PCSK9 mRNA CTD PMID:31199489 NCBI chr 5:121,211,278...121,233,688
Ensembl chr 5:121,211,278...121,233,688
JBrowse link
G Pdcd1 programmed cell death 1 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of PDCD1 mRNA CTD PMID:30171875 NCBI chr 9:94,418,786...94,431,945
Ensembl chr 9:94,418,791...94,431,937
JBrowse link
G Pfdn6 prefoldin subunit 6 affects response to substance ISO PFDN6 SNP affects the susceptibility to Benzalkonium Compounds CTD PMID:27258892 NCBI chr20:4,945,959...4,947,433
Ensembl chr20:4,945,959...4,947,433
JBrowse link
G Pglyrp3 peptidoglycan recognition protein 3 increases expression ISO Benzalkonium Compounds results in increased expression of PGLYRP3 mRNA CTD PMID:30171875 NCBI chr 2:177,479,693...177,490,867
Ensembl chr 2:176,855,732...176,874,162
Ensembl chr 2:176,855,732...176,874,162
JBrowse link
G Pgp phosphoglycolate phosphatase increases expression ISO Benzalkonium Compounds results in increased expression of PGP mRNA CTD PMID:31199489 NCBI chr10:13,495,232...13,497,858
Ensembl chr10:13,494,291...13,497,858
JBrowse link
G Pla2g5 phospholipase A2, group V decreases expression ISO Benzalkonium Compounds results in decreased expression of PLA2G5 mRNA CTD PMID:30171875 NCBI chr 5:151,041,339...151,109,433
Ensembl chr 5:151,041,340...151,062,658
JBrowse link
G Plcxd3 phosphatidylinositol-specific phospholipase C, X domain containing 3 increases expression ISO Benzalkonium Compounds results in increased expression of PLCXD3 mRNA CTD PMID:31199489 NCBI chr 2:53,567,022...53,746,384
Ensembl chr 2:53,567,022...53,746,384
JBrowse link
G Pnpla2 patatin-like phospholipase domain containing 2 decreases expression ISO Benzalkonium Compounds results in decreased expression of PNPLA2 mRNA CTD PMID:31199489 NCBI chr 1:196,552,723...196,557,805
Ensembl chr 1:196,552,723...196,557,805
JBrowse link
G Polr1d RNA polymerase I and III subunit D decreases expression ISO Benzalkonium Compounds results in decreased expression of POLR1D mRNA CTD PMID:31199489 NCBI chr12:7,970,592...8,004,157
Ensembl chr12:7,970,595...8,005,624
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha decreases expression ISO Benzalkonium Compounds results in decreased expression of PPARA mRNA CTD PMID:31199489 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Prkaa2 protein kinase AMP-activated catalytic subunit alpha 2 increases expression ISO Benzalkonium Compounds results in increased expression of PRKAA2 mRNA CTD PMID:31199489 NCBI chr 5:119,807,992...119,879,987
Ensembl chr 5:119,813,226...119,879,543
JBrowse link
G Prkag2 protein kinase AMP-activated non-catalytic subunit gamma 2 increases expression ISO Benzalkonium Compounds results in increased expression of PRKAG2 mRNA CTD PMID:31199489 NCBI chr 4:10,010,574...10,252,152
Ensembl chr 4:10,010,890...10,252,142
JBrowse link
G Prokr2 prokineticin receptor 2 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of PROKR2 mRNA CTD PMID:30171875 NCBI chr 3:119,624,738...119,639,442
Ensembl chr 3:119,627,601...119,635,718
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression ISO Benzalkonium Compounds results in increased expression of PTGS2 mRNA CTD PMID:30806763 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Ptx3 pentraxin 3 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of PTX3 mRNA CTD PMID:30171875 NCBI chr 2:150,487,513...150,493,323
Ensembl chr 2:150,487,513...150,493,323
JBrowse link
G Reg1a regenerating family member 1 alpha multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of REG1 mRNA CTD PMID:30171875 NCBI chr 4:110,892,451...110,895,115
Ensembl chr 4:110,892,453...110,895,570
JBrowse link
G Reg3g regenerating family member 3 gamma multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of REG3G mRNA CTD PMID:30171875 NCBI chr 4:110,922,805...110,927,803
Ensembl chr 4:110,924,168...110,926,723
JBrowse link
G Rgl2 ral guanine nucleotide dissociation stimulator-like 2 affects response to substance ISO RGL2 SNP affects the susceptibility to Benzalkonium Compounds CTD PMID:27258892 NCBI chr20:4,948,495...4,956,774
Ensembl chr20:4,948,497...4,969,911
JBrowse link
G Rps18 ribosomal protein S18 affects response to substance ISO RPS18 SNP affects the susceptibility to Benzalkonium Compounds CTD PMID:27258892 NCBI chr20:4,931,427...4,935,538 JBrowse link
G RT1-DOa RT1 class II, locus DOa affects response to substance ISO HLA-DOA SNP affects the susceptibility to Benzalkonium Compounds CTD PMID:27258892 NCBI chr20:4,753,587...4,756,590
Ensembl chr20:4,753,598...4,756,577
JBrowse link
G RT1-DOb RT1 class II, locus DOb affects response to substance ISO HLA-DOB SNP affects the susceptibility to Benzalkonium Compounds CTD PMID:27258892 NCBI chr20:4,619,599...4,625,627
Ensembl chr20:4,619,816...4,625,667
JBrowse link
G RT1-Ha RT1 class II, locus Ha affects response to substance ISO HLA-DPA1 SNP affects the susceptibility to Benzalkonium Compounds CTD PMID:27258892 NCBI chr20:4,760,631...4,770,662 JBrowse link
G Ryr1 ryanodine receptor 1 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of RYR1 mRNA CTD PMID:30171875 NCBI chr 1:84,292,578...84,423,799
Ensembl chr 1:84,292,578...84,423,812
JBrowse link
G Scd stearoyl-CoA desaturase increases expression
decreases expression
ISO Benzalkonium Compounds results in increased expression of SCD mRNA
Benzalkonium Compounds results in decreased expression of SCD1 mRNA
CTD PMID:29155129 PMID:31199489 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
JBrowse link
G Serpinb13 serpin family B member 13 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of SERPINB13 mRNA CTD PMID:30171875 NCBI chr13:23,118,584...23,150,760
Ensembl chr13:23,118,584...23,150,760
JBrowse link
G Serpine1 serpin family E member 1 increases expression ISO Benzalkonium Compounds results in increased expression of SERPINE1 mRNA CTD PMID:30171875 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
JBrowse link
G Sesn2 sestrin 2 decreases expression ISO Benzalkonium Compounds results in decreased expression of SESN2 mRNA CTD PMID:31199489 NCBI chr 5:144,702,287...144,721,241
Ensembl chr 5:144,701,530...144,721,260
JBrowse link
G Sfn stratifin increases expression ISO Benzalkonium Compounds results in increased expression of SFN mRNA CTD PMID:30171875 Ensembl chr 5:145,826,201...145,831,314 JBrowse link
G Sfrp4 secreted frizzled-related protein 4 decreases expression ISO Benzalkonium Compounds results in decreased expression of SFRP4 mRNA CTD PMID:30171875 NCBI chr17:45,278,867...45,330,806
Ensembl chr17:45,234,097...45,330,736
JBrowse link
G Siglec8 sialic acid binding Ig-like lectin 8 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of SIGLECE mRNA CTD PMID:30171875 NCBI chr 1:94,092,737...94,103,134
Ensembl chr 1:94,093,395...94,103,034
JBrowse link
G Slc16a1 solute carrier family 16 member 1 increases expression ISO Benzalkonium Compounds results in increased expression of SLC16A1 mRNA CTD PMID:31199489 NCBI chr 2:192,123,755...192,144,617
Ensembl chr 2:192,124,289...192,144,611
JBrowse link
G Slc7a11 solute carrier family 7 member 11 increases expression ISO Benzalkonium Compounds results in increased expression of SLC7A11 mRNA CTD PMID:30806763 NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536
JBrowse link
G Sox21 SRY-box transcription factor 21 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of SOX21 mRNA CTD PMID:30171875 NCBI chr15:95,292,272...95,295,316 JBrowse link
G Sprr1a small proline-rich protein 1A increases expression ISO Benzalkonium Compounds results in increased expression of SPRR1A mRNA CTD PMID:30171875 NCBI chr 2:178,055,096...178,057,012
Ensembl chr 2:178,055,096...178,057,063
JBrowse link
G Sprr1b small proline-rich protein 1B increases expression ISO Benzalkonium Compounds results in increased expression of SPRR1B mRNA CTD PMID:30171875 NCBI chr 2:178,009,130...178,009,567
Ensembl chr 2:178,009,130...178,009,567
JBrowse link
G Sprr2f small proline rich protein 2F increases expression ISO Benzalkonium Compounds results in increased expression of SPRR2F mRNA CTD PMID:30171875 NCBI chr 2:177,989,974...177,990,204 JBrowse link
G Sqle squalene epoxidase increases expression ISO Benzalkonium Compounds results in increased expression of SQLE mRNA CTD PMID:31199489 NCBI chr 7:90,867,973...90,883,623
Ensembl chr 7:90,868,011...90,883,618
JBrowse link
G Srebf2 sterol regulatory element binding transcription factor 2 increases expression ISO Benzalkonium Compounds results in increased expression of SREBF2 mRNA CTD PMID:26919959 NCBI chr 7:113,663,202...113,720,850
Ensembl chr 7:113,663,202...113,720,848
JBrowse link
G Srms src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of SRMS mRNA CTD PMID:30171875 NCBI chr 3:168,318,511...168,324,915
Ensembl chr 3:168,318,512...168,324,915
JBrowse link
G St14 ST14 transmembrane serine protease matriptase multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of ST14 mRNA CTD PMID:30171875 NCBI chr 8:29,540,805...29,581,704
Ensembl chr 8:29,540,811...29,581,517
JBrowse link
G Tapbp TAP binding protein affects response to substance ISO TAPBP SNP affects the susceptibility to Benzalkonium Compounds CTD PMID:27258892 NCBI chr20:4,956,937...4,966,191
Ensembl chr20:4,956,937...4,966,181
JBrowse link
G Tfap2b transcription factor AP-2 beta multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of TFAP2B mRNA CTD PMID:30171875 NCBI chr 9:21,786,250...21,815,785
Ensembl chr 9:21,786,258...21,814,520
JBrowse link
G Tgfb1 transforming growth factor, beta 1 increases expression ISO Benzalkonium Compounds results in increased expression of TGFB1 protein CTD PMID:30517752 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tgm3 transglutaminase 3 increases expression ISO Benzalkonium Compounds results in increased expression of TGM3 mRNA CTD PMID:30171875 NCBI chr 3:117,228,661...117,264,078
Ensembl chr 3:117,228,661...117,264,075
JBrowse link
G Tgm7 transglutaminase 7 decreases expression ISO Benzalkonium Compounds results in decreased expression of TGM7 mRNA CTD PMID:30171875 NCBI chr 3:108,051,890...108,068,116
Ensembl chr 3:108,051,890...108,076,239
JBrowse link
G Thbs1 thrombospondin 1 increases expression ISO Benzalkonium Compounds results in increased expression of THBS1 mRNA CTD PMID:30171875 NCBI chr 3:105,056,286...105,071,445
Ensembl chr 3:105,056,292...105,071,440
JBrowse link
G Tlr1 toll-like receptor 1 increases expression ISO Benzalkonium Compounds results in increased expression of TLR1 mRNA CTD PMID:30171875 NCBI chr14:43,384,127...43,396,765
Ensembl chr14:43,384,932...43,397,125
JBrowse link
G Tlr4 toll-like receptor 4 increases activity ISO Benzalkonium Compounds results in increased activity of TLR4 protein CTD PMID:29514330 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Tmprss11b transmembrane serine protease 11B increases expression ISO Benzalkonium Compounds results in increased expression of TMPRSS11B mRNA CTD PMID:30171875 NCBI chr14:21,385,924...21,405,894
Ensembl chr14:21,383,862...21,408,817
JBrowse link
G Tnf tumor necrosis factor decreases secretion
increases expression
ISO Benzalkonium Compounds results in decreased secretion of TNF protein
Benzalkonium Compounds results in increased expression of TNF mRNA; Benzalkonium Compounds results in increased expression of TNF protein
CTD PMID:29953848 PMID:30171875 PMID:30517752 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfaip6 TNF alpha induced protein 6 increases expression ISO Benzalkonium Compounds results in increased expression of TNFAIP6 mRNA CTD PMID:30171875 NCBI chr 3:36,502,250...36,521,652
Ensembl chr 3:36,502,188...36,521,649
JBrowse link
G Tnfrsf13c TNF receptor superfamily member 13C multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of TNFRSF13C mRNA CTD PMID:30171875 NCBI chr 7:113,736,046...113,738,523
Ensembl chr 7:113,736,055...113,738,517
JBrowse link
G Tnfrsf9 TNF receptor superfamily member 9 increases expression ISO Benzalkonium Compounds results in increased expression of TNFRSF9 mRNA CTD PMID:30171875 NCBI chr 5:161,381,662...161,408,003
Ensembl chr 5:161,381,662...161,408,000
JBrowse link
G Tnfsf8 TNF superfamily member 8 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of TNFSF8 mRNA CTD PMID:30171875 NCBI chr 5:77,253,881...77,277,078
Ensembl chr 5:77,251,373...77,277,421
JBrowse link
G Tp53 tumor protein p53 decreases expression ISO Benzalkonium Compounds results in decreased expression of TP53 mRNA CTD PMID:28236482 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Tpi1 triosephosphate isomerase 1 decreases expression ISO Benzalkonium Compounds results in decreased expression of TPI1 mRNA CTD PMID:31199489 NCBI chr 4:157,615,283...157,618,813
Ensembl chr 4:157,615,386...157,619,541
JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 increases expression ISO Benzalkonium Compounds results in increased expression of TREM2 mRNA CTD PMID:30171875 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170
JBrowse link
G Tslp thymic stromal lymphopoietin multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of TSLP mRNA CTD PMID:30171875 NCBI chr18:24,447,409...24,454,244
Ensembl chr18:24,449,844...24,453,548
JBrowse link
G Upk3b uroplakin 3B decreases expression ISO Benzalkonium Compounds results in decreased expression of UPK3B mRNA CTD PMID:30171875 NCBI chr12:20,629,491...20,638,193
Ensembl chr12:20,631,525...20,637,724
JBrowse link
G Uqcrq ubiquinol-cytochrome c reductase, complex III subunit VII decreases expression ISO Benzalkonium Compounds results in decreased expression of UQCRQ mRNA CTD PMID:31199489 NCBI chr10:37,585,864...37,589,328
Ensembl chr10:37,586,888...37,589,169
JBrowse link
G Vegfd vascular endothelial growth factor D increases expression ISO Benzalkonium Compounds results in increased expression of VEGFD mRNA CTD PMID:20146380 NCBI chr  X:30,073,122...30,108,413
Ensembl chr  X:30,074,163...30,108,295
JBrowse link
G Vtcn1 V-set domain containing T cell activation inhibitor 1 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of VTCN1 mRNA CTD PMID:30171875 NCBI chr 2:188,253,594...188,321,658
Ensembl chr 2:188,253,594...188,321,658
JBrowse link
G Wdr46 WD repeat domain 46 affects response to substance ISO WDR46 SNP affects the susceptibility to Benzalkonium Compounds CTD PMID:27258892 NCBI chr20:4,937,845...4,945,796
Ensembl chr20:4,937,847...4,946,535
JBrowse link
G Xbp1 X-box binding protein 1 decreases expression ISO Benzalkonium Compounds results in decreased expression of XBP1 mRNA alternative form CTD PMID:28236482 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693
JBrowse link
G Xcl1 X-C motif chemokine ligand 1 decreases expression ISO Benzalkonium Compounds results in decreased expression of XCL1 mRNA CTD PMID:30171875 NCBI chr13:77,248,865...77,252,308
Ensembl chr13:77,248,717...77,252,329
JBrowse link
butylscopolamine bromide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Butylscopolammonium Bromide inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268
JBrowse link
chlormequat chloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor multiple interactions ISO Chlormequat promotes the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein] CTD PMID:25684042 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Bglap bone gamma-carboxyglutamate protein decreases expression EXP Chlormequat results in decreased expression of BGLAP protein CTD PMID:28214531 NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 decreases expression EXP Chlormequat results in decreased expression of CYP11A1 protein CTD PMID:29447956 NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 increases expression ISO Chlormequat results in increased expression of CYP7A1 protein CTD PMID:32194361 NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
JBrowse link
G Gh1 growth hormone 1 increases expression EXP Chlormequat results in increased expression of GH1 protein CTD PMID:31704167 PMID:32622971 NCBI chr10:91,228,102...91,230,079
Ensembl chr10:91,228,103...91,230,078
JBrowse link
G Ghr growth hormone receptor decreases expression EXP Chlormequat results in decreased expression of GHR mRNA CTD PMID:28214531 NCBI chr 2:52,541,452...52,804,960
Ensembl chr 2:52,542,594...52,804,735
JBrowse link
G Ghrh growth hormone releasing hormone increases expression EXP Chlormequat results in increased expression of GHRH protein CTD PMID:32622971 NCBI chr 3:145,992,762...146,012,528
Ensembl chr 3:145,992,763...146,011,889
JBrowse link
G Gnrh1 gonadotropin releasing hormone 1 increases expression EXP Chlormequat results in increased expression of GNRH1 protein CTD PMID:29447956 NCBI chr15:41,972,482...41,976,690
Ensembl chr15:41,972,905...41,973,581
Ensembl chr15:41,972,905...41,973,581
JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 decreases expression EXP Chlormequat results in decreased expression of HSD3B1 protein CTD PMID:29447956 NCBI chr 2:186,169,864...186,175,984
Ensembl chr 2:186,169,863...186,175,999
JBrowse link
G Igf1 insulin-like growth factor 1 affects expression
increases expression
EXP Chlormequat affects the expression of IGF1 protein
Chlormequat results in increased expression of IGF1 protein
CTD PMID:28214531 PMID:31704167 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Lhb luteinizing hormone subunit beta increases expression EXP Chlormequat results in increased expression of LHB protein CTD PMID:29447956 NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972
Ensembl chr 1:95,900,984...95,901,972
JBrowse link
G Star steroidogenic acute regulatory protein decreases expression EXP Chlormequat results in decreased expression of STAR protein CTD PMID:29447956 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672
JBrowse link
G Tnfsf11 TNF superfamily member 11 affects expression EXP Chlormequat affects the expression of TNFSF11 mRNA CTD PMID:28214531 NCBI chr15:53,674,990...53,705,171
Ensembl chr15:53,673,877...53,705,445
JBrowse link
colesevelam hydrochloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crp C-reactive protein decreases expression ISO Colesevelam Hydrochloride results in decreased expression of CRP protein CTD PMID:16616026 NCBI chr13:85,131,635...85,175,179
Ensembl chr13:85,124,977...85,175,178
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase multiple interactions
increases expression
ISO Colesevelam Hydrochloride promotes the reaction [Simvastatin results in increased expression of HMGCR mRNA]
Colesevelam Hydrochloride results in increased expression of HMGCR mRNA
CTD PMID:22120639 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
JBrowse link
G Ldlr low density lipoprotein receptor increases expression ISO Colesevelam Hydrochloride results in increased expression of LDLR mRNA CTD PMID:22120639 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
JBrowse link
colforsin daropate hydrochloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions
increases expression
ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Colforsin results in increased expression of ABCB1 mRNA] CTD PMID:12926078 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcb4 ATP binding cassette subfamily B member 4 multiple interactions
decreases expression
ISO Colforsin inhibits the reaction [Doxorubicin results in increased expression of ABCB4 mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Colforsin results in decreased expression of ABCB4 mRNA] CTD PMID:12926078 NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 increases expression ISO Colforsin results in increased expression of ABCC2 mRNA; Colforsin results in increased expression of ABCC2 protein CTD PMID:19580841 PMID:26049102 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 increases expression
multiple interactions
ISO Colforsin results in increased expression of ABCG2 mRNA
Colforsin inhibits the reaction [anandamide inhibits the reaction [CREB1 protein modified form binds to ABCG2 promoter]]
CTD PMID:19580841 PMID:30610963 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409
JBrowse link
G Acaca acetyl-CoA carboxylase alpha increases phosphorylation ISO Colforsin results in increased phosphorylation of ACACA protein CTD PMID:18390901 NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457
JBrowse link
G Ache acetylcholinesterase increases activity
increases expression
EXP Colforsin results in increased activity of ACHE protein; Colforsin results in increased activity of ACHE protein alternative form
Colforsin results in increased expression of ACHE mRNA
CTD PMID:18514641 NCBI chr12:19,407,359...19,413,713
Ensembl chr12:19,407,360...19,413,651
JBrowse link
G Acsl3 acyl-CoA synthetase long-chain family member 3 increases expression ISO Colforsin results in increased expression of ACSL3 mRNA CTD PMID:16751804 NCBI chr 9:80,140,996...80,164,636
Ensembl chr 9:80,115,112...80,164,627
JBrowse link
G Acta2 actin alpha 2, smooth muscle decreases expression
multiple interactions
ISO
EXP
Colforsin results in decreased expression of ACTA2 protein
Colforsin inhibits the reaction [Carbon Tetrachloride results in increased expression of ACTA2 protein]
CTD PMID:21603974 PMID:27590029 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
JBrowse link
G Adam12 ADAM metallopeptidase domain 12 decreases expression ISO Colforsin results in decreased expression of ADAM12 mRNA CTD PMID:15313392 PMID:15967414 NCBI chr 1:188,686,984...189,014,206
Ensembl chr 1:188,686,989...189,020,667
JBrowse link
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 decreases expression ISO Colforsin results in decreased expression of ADAMTS1 mRNA CTD PMID:15313392 PMID:15967414 NCBI chr11:24,932,227...24,941,068
Ensembl chr11:24,931,761...24,941,103
JBrowse link
G Adcy5 adenylate cyclase 5 multiple interactions ISO ADCY5 protein results in increased susceptibility to [Colforsin co-treated with Quinpirole] CTD PMID:12223546 NCBI chr11:65,471,612...65,618,877
Ensembl chr11:65,471,612...65,618,974
JBrowse link
G Adcy6 adenylate cyclase 6 affects response to substance ISO ADCY6 protein affects the susceptibility to Colforsin CTD PMID:12393090 NCBI chr 7:129,742,827...129,763,922
Ensembl chr 7:129,742,838...129,763,754
JBrowse link
G Adcy9 adenylate cyclase 9 multiple interactions
increases activity
ISO [Colforsin co-treated with Miconazole] results in increased activity of ADCY9 protein
Colforsin results in increased activity of ADCY9 protein
CTD PMID:30607468 NCBI chr10:11,138,966...11,262,067
Ensembl chr10:11,139,446...11,262,066
JBrowse link
G Adra1a adrenoceptor alpha 1A multiple interactions ISO [Colforsin co-treated with 1-Methyl-3-isobutylxanthine] affects the reaction [[Phenylephrine binds to and results in increased activity of ADRA1A protein] which affects the transport of Potassium] CTD PMID:19419905 NCBI chr15:40,830,125...40,935,902
Ensembl chr15:40,832,534...40,927,500
JBrowse link
G Adra2c adrenoceptor alpha 2C multiple interactions
affects localization
increases expression
ISO AKAP13 protein modified form affects the reaction [Colforsin affects the localization of ADRA2C protein]; AKAP13 protein modified form affects the reaction [Colforsin results in increased expression of ADRA2C mRNA] CTD PMID:24701590 NCBI chr14:75,471,143...75,472,846
Ensembl chr14:75,471,143...75,472,846
JBrowse link
G Adrb1 adrenoceptor beta 1 affects response to substance
multiple interactions
ISO ADRB1 protein polymorphism affects the susceptibility to Colforsin
[[Colforsin co-treated with 1-Methyl-3-isobutylxanthine] results in increased activity of [ADRB1 protein binds to ADRB2 protein]] affects the reaction [KCNH2 protein results in increased transport of Potassium]; [Colforsin co-treated with 1-Methyl-3-isobutylxanthine] promotes the reaction [[ADRB1 protein binds to ADRB2 protein] which results in increased abundance of Cyclic AMP]; [Colforsin co-treated with 1-Methyl-3-isobutylxanthine] results in increased activity of [ADRB1 protein binds to ADRB2 protein]
CTD PMID:14502278 PMID:19419905 NCBI chr 1:255,772,217...255,773,617
Ensembl chr 1:255,771,597...255,807,259
JBrowse link
G Adrb2 adrenoceptor beta 2 multiple interactions
increases expression
increases phosphorylation
ISO [[Colforsin co-treated with 1-Methyl-3-isobutylxanthine] results in increased activity of [ADRB1 protein binds to ADRB2 protein]] affects the reaction [KCNH2 protein results in increased transport of Potassium]; [Colforsin co-treated with 1-Methyl-3-isobutylxanthine] promotes the reaction [[ADRB1 protein binds to ADRB2 protein] which results in increased abundance of Cyclic AMP]; [Colforsin co-treated with 1-Methyl-3-isobutylxanthine] results in increased activity of [ADRB1 protein binds to ADRB2 protein]
Colforsin results in increased expression of ADRB2 mRNA
Colforsin results in increased phosphorylation of ADRB2 protein
CTD PMID:14722251 PMID:19419905 PMID:24705868 NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512
JBrowse link
G Adrb3 adrenoceptor beta 3 decreases expression ISO Colforsin results in decreased expression of ADRB3 mRNA CTD PMID:10725275 NCBI chr16:64,839,820...64,844,552
Ensembl chr16:64,841,788...64,844,552
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions
affects localization
ISO [Colforsin results in increased activity of AHR protein] which results in increased expression of CXCL8 mRNA; [Colforsin results in increased activity of AHR protein] which results in increased expression of CXCL8 protein; [Colforsin results in increased activity of AHR protein] which results in increased secretion of CXCL8 protein; Colforsin promotes the reaction [[AHR protein binds to RELB protein] which binds to CXCL8 promoter]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Colforsin promotes the reaction [[AHR protein binds to RELB protein] which binds to CXCL8 promoter]]; PDE2A protein inhibits the reaction [Colforsin affects the localization of AHR protein]
AHR protein inhibits the reaction [[Colforsin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PER1 mRNA]
CTD PMID:15972329 PMID:17329248 PMID:17823304 PMID:23291558 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Akap13 A-kinase anchoring protein 13 multiple interactions ISO AKAP13 protein modified form affects the reaction [Colforsin affects the localization of ADRA2C protein]; AKAP13 protein modified form affects the reaction [Colforsin results in increased expression of ADRA2C mRNA]; AKAP13 protein modified form inhibits the reaction [Colforsin results in increased phosphorylation of CREB1 protein] CTD PMID:24701590 NCBI chr 1:129,313,183...129,619,647
Ensembl chr 1:129,314,402...129,619,646
JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 decreases expression ISO Colforsin results in decreased expression of AKR1C3 mRNA CTD PMID:28235592 NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions EXP Colforsin inhibits the reaction [Oxidopamine results in decreased phosphorylation of AKT1 protein] CTD PMID:16339297 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Akt2 AKT serine/threonine kinase 2 multiple interactions EXP Colforsin inhibits the reaction [Oxidopamine results in decreased phosphorylation of AKT2 protein] CTD PMID:16339297 NCBI chr 1:82,877,228...82,933,828
Ensembl chr 1:82,883,547...82,933,817
JBrowse link
G Akt3 AKT serine/threonine kinase 3 multiple interactions EXP Colforsin inhibits the reaction [Oxidopamine results in decreased phosphorylation of AKT3 protein] CTD PMID:16339297 NCBI chr13:88,943,708...89,225,831
Ensembl chr13:88,946,091...89,225,708
JBrowse link
G Alb albumin multiple interactions EXP Colforsin inhibits the reaction [Carbon Tetrachloride results in decreased expression of ALB protein] CTD PMID:27590029 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Alpi alkaline phosphatase, intestinal multiple interactions ISO Colforsin inhibits the reaction [Methotrexate results in increased activity of ALPI protein] CTD PMID:16598758 NCBI chr 9:87,773,411...87,776,877
Ensembl chr 9:87,773,411...87,776,877
JBrowse link
G Alpp alkaline phosphatase, placental increases expression
multiple interactions
ISO Colforsin results in increased expression of ALPP mRNA
[Colforsin results in increased abundance of Cyclic AMP] which results in increased expression of ALPP mRNA; Chlorpromazine inhibits the reaction [Colforsin results in increased expression of ALPP mRNA]; Clozapine inhibits the reaction [Colforsin results in increased expression of ALPP mRNA]; Desipramine inhibits the reaction [Colforsin results in increased expression of ALPP mRNA]
CTD PMID:16036225 NCBI chr 9:87,765,846...87,768,606
Ensembl chr 9:87,765,860...87,768,606
JBrowse link
G Aoc1 amine oxidase, copper containing 1 increases activity EXP Colforsin results in increased activity of AOC1 protein CTD PMID:2860926 NCBI chr 4:77,812,260...77,831,846
Ensembl chr 4:77,812,260...77,831,840
JBrowse link
G Appbp2 amyloid beta precursor protein binding protein 2 decreases expression ISO Colforsin results in decreased expression of APPBP2 mRNA CTD PMID:16751804 NCBI chr10:70,057,774...70,099,877
Ensembl chr10:70,057,774...70,099,835
JBrowse link
G Ar androgen receptor multiple interactions
increases expression
ISO AR protein affects the reaction [Colforsin results in decreased expression of SESN1 protein]; AR protein promotes the reaction [Colforsin results in increased expression of HMGCR protein]; AR protein promotes the reaction [Colforsin results in increased expression of INSIG1 protein]; AR protein promotes the reaction [Colforsin results in increased expression of KLK2 protein]; AR protein promotes the reaction [Colforsin results in increased expression of KLK3 protein]; Colforsin promotes the reaction [Metribolone results in increased activity of AR protein]
Colforsin results in increased expression of AR protein
CTD PMID:16751804 PMID:17219378 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Areg amphiregulin increases expression
multiple interactions
ISO Colforsin results in increased expression of AREG mRNA
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Colforsin results in increased expression of AREG mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Colforsin results in increased expression of AREG protein]
CTD PMID:15284208 PMID:15313392 PMID:15474502 PMID:15967414 PMID:20378682 NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535
JBrowse link
G Arntl aryl hydrocarbon receptor nuclear translocator-like increases expression ISO Colforsin results in increased expression of ARNTL mRNA CTD PMID:30524225 NCBI chr 1:167,331,756...167,430,235
Ensembl chr 1:167,331,633...167,430,231
JBrowse link
G Arrb1 arrestin, beta 1 multiple interactions ISO Colforsin inhibits the reaction [[carvedilol co-treated with ARRB1 protein] results in increased expression of MIR190A mRNA] CTD PMID:24334028 NCBI chr 1:153,837,964...153,912,111
Ensembl chr 1:153,838,078...153,904,061
JBrowse link
G Atxn3 ataxin 3 decreases expression ISO Colforsin results in decreased expression of ATXN3 mRNA CTD PMID:16751804 NCBI chr 6:121,072,228...121,107,902
Ensembl chr 6:121,074,448...121,107,902
JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions
increases expression
ISO 1-bromopropane inhibits the reaction [Colforsin results in increased expression of BDNF mRNA]; 1-bromopropane inhibits the reaction [Colforsin results in increased expression of BDNF protein]
Colforsin results in increased expression of BDNF mRNA; Colforsin results in increased expression of BDNF protein
CTD PMID:19189864 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G Bmp6 bone morphogenetic protein 6 multiple interactions ISO BMP6 protein inhibits the reaction [Colforsin results in increased expression of CYP11A1 mRNA]; BMP6 protein inhibits the reaction [Colforsin results in increased expression of CYP19A1 mRNA]; BMP6 protein inhibits the reaction [Colforsin results in increased expression of HSD3B1 mRNA]; BMP6 protein inhibits the reaction [Colforsin results in increased expression of OXT mRNA]; BMP6 protein inhibits the reaction [Colforsin results in increased expression of STAR mRNA]; BMP6 protein inhibits the reaction [Colforsin results in increased secretion of Progesterone]; FST protein inhibits the reaction [BMP6 protein inhibits the reaction [Colforsin results in increased secretion of Progesterone]] CTD PMID:18936084 NCBI chr17:26,318,121...26,469,034
Ensembl chr17:26,318,569...26,470,365
JBrowse link
G Cacna1g calcium voltage-gated channel subunit alpha1 G multiple interactions EXP Mibefradil inhibits the reaction [[Colforsin co-treated with 1-Methyl-3-isobutylxanthine] results in increased activity of CACNA1G protein]; Nickel inhibits the reaction [[Colforsin co-treated with 1-Methyl-3-isobutylxanthine] results in increased activity of CACNA1G protein] CTD PMID:17110049 NCBI chr10:79,354,998...79,422,960
Ensembl chr10:79,355,008...79,422,752
JBrowse link
G Cacna1h calcium voltage-gated channel subunit alpha1 H multiple interactions EXP Mibefradil inhibits the reaction [[Colforsin co-treated with 1-Methyl-3-isobutylxanthine] results in increased activity of CACNA1H protein]; Nickel inhibits the reaction [[Colforsin co-treated with 1-Methyl-3-isobutylxanthine] results in increased activity of CACNA1H protein] CTD PMID:17110049 NCBI chr10:14,390,104...14,448,204
Ensembl chr10:14,390,113...14,448,376
JBrowse link
G Cacna1i calcium voltage-gated channel subunit alpha1 I multiple interactions EXP Mibefradil inhibits the reaction [[Colforsin co-treated with 1-Methyl-3-isobutylxanthine] results in increased activity of CACNA1I protein]; Nickel inhibits the reaction [[Colforsin co-treated with 1-Methyl-3-isobutylxanthine] results in increased activity of CACNA1I protein] CTD PMID:17110049 NCBI chr 7:111,835,996...111,947,418
Ensembl chr 7:111,836,012...111,944,688
JBrowse link
G Calcrl calcitonin receptor like receptor multiple interactions ISO Colforsin inhibits the reaction [EDN1 protein results in increased expression of CALCRL mRNA] CTD PMID:25194819 NCBI chr 3:69,428,348...69,525,910
Ensembl chr 3:69,430,120...69,525,910
JBrowse link
G Camkk2 calcium/calmodulin-dependent protein kinase kinase 2 increases expression ISO Colforsin results in increased expression of CAMKK2 mRNA CTD PMID:16751804 NCBI chr12:33,791,023...33,845,000
Ensembl chr12:33,791,052...33,843,279
JBrowse link
G Cask calcium/calmodulin dependent serine protein kinase multiple interactions
increases phosphorylation
EXP Colforsin promotes the reaction [CASK protein modified form binds to TBR1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Colforsin results in increased phosphorylation of CASK protein] CTD PMID:20067577 NCBI chr  X:8,899,500...9,243,014
Ensembl chr  X:8,899,833...9,238,694
JBrowse link
G Casp1 caspase 1 increases activity EXP Colforsin results in increased activity of CASP1 mRNA; Colforsin results in increased activity of CASP1 protein CTD PMID:21832250 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
JBrowse link
G Casp3 caspase 3 increases activity
multiple interactions
ISO
EXP
Colforsin results in increased activity of CASP3 protein
Colforsin inhibits the reaction [Puromycin Aminonucleoside results in increased activity of CASP3 protein]
KT 5720 inhibits the reaction [Colforsin results in increased activity of CASP3 protein]
Colforsin inhibits the reaction [Cisplatin results in increased cleavage of and results in increased activity of CASP3 protein]
CTD PMID:16396944 PMID:20131233 PMID:21745194 PMID:31278978 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Cat catalase multiple interactions EXP Colforsin inhibits the reaction [mancozeb results in decreased activity of CAT protein] CTD PMID:29283200 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 multiple interactions ISO Colforsin inhibits the reaction [Reactive Oxygen Species results in increased expression of CCL5 mRNA]; Colforsin inhibits the reaction [TNF protein results in increased expression of CCL5 mRNA] CTD PMID:10495789 NCBI chr10:68,322,826...68,327,365
Ensembl chr10:68,322,829...68,327,377
JBrowse link
G Cd55 CD55 molecule (Cromer blood group) multiple interactions
increases expression
ISO 3',4'-dimethoxy-alpha-naphthoflavone inhibits the reaction [Colforsin results in increased expression of CD55 mRNA] CTD PMID:22553215 NCBI chr13:41,857,242...41,885,966
Ensembl chr13:41,857,395...41,885,831
JBrowse link
G Cdc6 cell division cycle 6 increases expression ISO Colforsin results in increased expression of CDC6 mRNA CTD PMID:16751804 NCBI chr10:83,864,189...83,878,011
Ensembl chr10:83,864,638...83,878,011
JBrowse link
G Cdh1 cadherin 1 affects activity
increases expression
ISO Colforsin affects the activity of CDH1 protein
Colforsin results in increased expression of CDH1 protein
CTD PMID:10413674 PMID:30983542 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha multiple interactions
increases expression
ISO
EXP
Colforsin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CEBPA mRNA]
Colforsin inhibits the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of CEBPA protein]
Colforsin results in increased expression of CEBPA protein
CTD PMID:17407152 PMID:21832167 NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta increases expression
multiple interactions
ISO
EXP
Colforsin results in increased expression of CEBPB mRNA
[Atrazine co-treated with Colforsin] results in increased expression of CEBPB protein
CTD PMID:14684744 PMID:25253736 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
JBrowse link
G Cftr CF transmembrane conductance regulator affects localization
increases activity
multiple interactions
ISO
EXP
Colforsin affects the localization of CFTR protein
Colforsin results in increased activity of CFTR protein
[Colforsin co-treated with Genistein] results in increased activity of CFTR protein; AICA ribonucleotide inhibits the reaction [Colforsin results in increased activity of CFTR protein]
[1-Methyl-3-isobutylxanthine co-treated with Colforsin] results in increased activity of CFTR protein
3-((3-trifluoromethyl)phenyl)-5-((3-carboxyphenyl)methylene)-2-thioxo-4-thiazolidinone inhibits the reaction [[[Colforsin co-treated with Genistein] results in increased activity of CFTR protein] which results in increased transport of Iodides]; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [Colforsin results in increased activity of CFTR protein]; 5-butyl-6-hydroxy-10-chlorobenzo(c)quinolizinium chloride inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]; 5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]; 6-hydroxy-10-chlorobenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]; [1-Methyl-3-isobutylxanthine co-treated with Colforsin] results in increased activity of CFTR protein; [1-Methyl-3-isobutylxanthine co-treated with Colforsin] results in increased activity of CFTR protein mutant form; [5-butyl-6-hydroxy-10-chlorobenzo(c)quinolizinium chloride co-treated with Colforsin] results in increased activity of CFTR protein mutant form; [[Colforsin co-treated with Genistein] results in increased activity of CFTR protein] which results in increased transport of Iodides; [Colforsin co-treated with 1-Methyl-3-isobutylxanthine] results in increased activity of CFTR protein; [Colforsin co-treated with Genistein] results in increased activity of CFTR protein; [Colforsin co-treated with lumacaftor] results in increased activity of CFTR protein mutant form; [Colforsin co-treated with NS 004] results in increased activity of CFTR protein mutant form; [ivacaftor co-treated with Colforsin co-treated with lumacaftor] results in increased activity of CFTR protein mutant form; [ivacaftor co-treated with Colforsin] results in increased activity of CFTR protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [miglustat inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]; Brefeldin A inhibits the reaction [5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]; Brefeldin A inhibits the reaction [miglustat inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]; CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]; Colforsin binds to and results in decreased activity of CFTR protein; Colforsin promotes the reaction [CFTR protein affects the export of Chlorides]; Colforsin results in increased phosphorylation of and results in increased activity of CFTR protein; fenamic acid inhibits the reaction [[[Colforsin co-treated with Genistein] results in increased activity of CFTR protein] which results in increased transport of Iodides]; fenamic acid inhibits the reaction [Colforsin results in increased activity of CFTR protein]; geldanamycin promotes the reaction [5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]; geldanamycin promotes the reaction [miglustat inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]; Glyburide inhibits the reaction [[[Colforsin co-treated with Genistein] results in increased activity of CFTR protein] which results in increased transport of Iodides]; Glyburide inhibits the reaction [Colforsin results in increased activity of CFTR protein]; miglustat inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Colforsin results in increased activity of CFTR protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Colforsin results in increased phosphorylation of CFTR protein]; Ozone inhibits the reaction [Colforsin results in increased activity of CFTR protein]; Thapsigargin promotes the reaction [5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]; Thapsigargin promotes the reaction [miglustat inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]; VRT 532 analog promotes the reaction [Colforsin results in increased activity of CFTR protein mutant form]; VRT 532 promotes the reaction [Colforsin results in increased activity of CFTR protein mutant form]
Colforsin analog results in increased activity of CFTR protein mutant form; Colforsin results in increased activity of CFTR protein; Colforsin results in increased activity of CFTR protein mutant form
CTD PMID:12519745 PMID:12914781 PMID:14502435 PMID:14967738 PMID:15163550 More... NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756
JBrowse link
G Cga glycoprotein hormones, alpha polypeptide increases secretion
increases expression
multiple interactions
ISO
EXP
Colforsin results in increased secretion of CGA protein
Colforsin results in increased expression of CGA protein
Colforsin results in increased expression of CGA mRNA
Colforsin promotes the reaction [CGA protein results in increased abundance of Cyclic AMP]; perfluorobutanesulfonic acid inhibits the reaction [Colforsin results in increased expression of CGA protein]; perfluorooctane sulfonic acid inhibits the reaction [Colforsin results in increased expression of CGA protein]
Colforsin inhibits the reaction [ESR2 gene mutant form inhibits the reaction [CGA protein results in increased abundance of Cyclic AMP]]
CTD PMID:8404651 PMID:16503475 PMID:20378682 PMID:33144174 NCBI chr 5:49,486,915...49,499,192
Ensembl chr 5:49,487,068...49,499,191
JBrowse link
G Cidec cell death-inducing DFFA-like effector c increases expression ISO Colforsin results in increased expression of CIDEC protein CTD PMID:21097823 NCBI chr 4:146,569,288...146,582,173
Ensembl chr 4:146,569,289...146,582,173
JBrowse link
G Cnr1 cannabinoid receptor 1 multiple interactions
affects response to substance
increases activity
ISO (1-(2-morpholin-4-yl-ethyl)-1H-indol-3-yl)-(2,2,3,3-tetramethylcyclopropyl)methanone inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; (1-pentyl-1H-indol-3-yl)(2,2,3,3-tetramethylcyclopropyl)methanone inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; (4-ethyl-1-naphthalenyl)(1-(5-fluoropentyl)-1H-indol-3-yl)methanone inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 1-(2-cyclohexylethyl)-3-(2-methoxyphenylacetyl)indole inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 1-(5-fluoropentyl)-3-(4-methyl-1-naphthoyl)indole analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 1-(5-fluoropentyl)-3-(4-methyl-1-naphthoyl)indole inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 1-(cyclohexylmethyl)-1H-indole-3-carboxylic acid 8-quinolinyl ester inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 1-pentyfluoro-1H-indole-3-carboxylic acid 8-quinolinyl ester inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 1-pentyl-1H-indole-3-carboxylic acid 8-quinolinyl ester inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 1-pentyl-3-(1-naphthoyl)indole analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 2-(4-methoxyphenyl)-1-(1-pentyl-indol-3-yl)methanone inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 3-((adamantan-1-yl)carbonyl)-1-pentylindole analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 3-((adamantan-1-yl)carbonyl)-1-pentylindole inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol inhibits the reaction [Colforsin results in increased activity of CNR1 protein]; [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]; [Dronabinol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]; [Medroxyprogesterone Acetate co-treated with Estradiol co-treated with Colforsin] results in increased expression of CNR1 mRNA; AM 6527 analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; AM 6527 inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; CNR1 protein inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]; delta(9)-tetrahydrocannabinolic acid inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol inhibits the reaction [Colforsin results in increased activity of CNR1 protein]]; delta(9)-tetrahydrocannabinolic acid inhibits the reaction [Colforsin results in increased activity of CNR1 protein]; Dronabinol inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; Dronabinol inhibits the reaction [Colforsin results in increased activity of CNR1 protein]; FDU-PB-22 inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; FUB-PB-22 compound inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; Indazoles analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; Indoles analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; N-(1-adamantyl)-1-(5-fluoropentyl)-1H-indazole-3-carboxamide inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; N-(1-adamantyl)-1-pentylindazole-3-carboxamide analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; N-(adamantan-1-yl)-1-(5-fluoropentyl)-1H-indole-3-carboxamide inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; N-(adamtan-1-yl)-1-pentyl-1H-indole-3-carboxamide analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; N-(adamtan-1-yl)-1-pentyl-1H-indole-3-carboxamide inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; N-1-naphthalenyl-1-pentyl-1H-indazole-3-carboxamide analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; N-1-naphthalenyl-1-pentyl-1H-indazole-3-carboxamide inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; napht-1-yl 1-(5-fluoropentyl)-1H-indole-3-carboxylate inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; THJ-2201 inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; XLR-11 analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; XLR-11 inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]
CNR1 protein affects the susceptibility to Colforsin
CTD PMID:27429655 PMID:27527584 PMID:28861508 PMID:31154070 NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099
JBrowse link
G Cnr2 cannabinoid receptor 2 multiple interactions
increases activity
affects response to substance
ISO (1-(2-morpholin-4-yl-ethyl)-1H-indol-3-yl)-(2,2,3,3-tetramethylcyclopropyl)methanone inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; (1-pentyl-1H-indol-3-yl)(2,2,3,3-tetramethylcyclopropyl)methanone inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; (4-ethyl-1-naphthalenyl)(1-(5-fluoropentyl)-1H-indol-3-yl)methanone inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 1-(2-cyclohexylethyl)-3-(2-methoxyphenylacetyl)indole inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 1-(5-fluoropentyl)-3-(4-methyl-1-naphthoyl)indole analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 1-(5-fluoropentyl)-3-(4-methyl-1-naphthoyl)indole inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 1-(cyclohexylmethyl)-1H-indole-3-carboxylic acid 8-quinolinyl ester inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 1-pentyfluoro-1H-indole-3-carboxylic acid 8-quinolinyl ester inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 1-pentyl-1H-indole-3-carboxylic acid 8-quinolinyl ester inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 1-pentyl-3-(1-naphthoyl)indole analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 2-(4-methoxyphenyl)-1-(1-pentyl-indol-3-yl)methanone inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 3-((adamantan-1-yl)carbonyl)-1-pentylindole analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 3-((adamantan-1-yl)carbonyl)-1-pentylindole inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol inhibits the reaction [Colforsin results in increased activity of CNR2 protein]; [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]; [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]; [Dronabinol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]; [Medroxyprogesterone Acetate co-treated with Estradiol co-treated with Colforsin] results in increased expression of CNR2 mRNA; [virodhamine binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]; AM 6527 analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; AM 6527 inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; CNR2 protein inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]; Dronabinol inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; Dronabinol inhibits the reaction [Colforsin results in increased activity of CNR2 protein]; FDU-PB-22 inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; FUB-PB-22 compound inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; Indazoles analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; Indoles analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; N-(1-adamantyl)-1-(5-fluoropentyl)-1H-indazole-3-carboxamide inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; N-(1-adamantyl)-1-pentylindazole-3-carboxamide analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; N-(adamantan-1-yl)-1-(5-fluoropentyl)-1H-indole-3-carboxamide inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; N-(adamtan-1-yl)-1-pentyl-1H-indole-3-carboxamide analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; N-(adamtan-1-yl)-1-pentyl-1H-indole-3-carboxamide inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; N-1-naphthalenyl-1-pentyl-1H-indazole-3-carboxamide analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; N-1-naphthalenyl-1-pentyl-1H-indazole-3-carboxamide inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; napht-1-yl 1-(5-fluoropentyl)-1H-indole-3-carboxylate inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; Pertussis Toxin inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]]; Pertussis Toxin inhibits the reaction [[virodhamine binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]]; SR 144528 inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]]; SR 144528 inhibits the reaction [[virodhamine binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]]; THJ-2201 inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; XLR-11 analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; XLR-11 inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]
CNR2 protein affects the susceptibility to Colforsin
CTD PMID:17558435 PMID:27429655 PMID:27527584 PMID:28861508 PMID:30504240 More... NCBI chr 5:148,125,222...148,151,548
Ensembl chr 5:148,125,604...148,151,548
JBrowse link
G Creb1 cAMP responsive element binding protein 1 increases activity
increases expression
increases phosphorylation
multiple interactions
ISO
EXP
Colforsin results in increased activity of CREB1 protein
Colforsin results in increased expression of CREB1 protein modified form
Colforsin results in increased phosphorylation of CREB1 protein
3-(3-chloro-4-hydroxyphenylamino)-4-(4-nitrophenyl)-1H-pyrrole-2,5-dione inhibits the reaction [resveratrol inhibits the reaction [Colforsin results in increased phosphorylation of CREB1 protein]]; Colforsin inhibits the reaction [Carbon Tetrachloride results in decreased expression of CREB1 protein modified form]; Colforsin promotes the reaction [CREB1 protein binds to POU1F1 promoter]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Colforsin results in increased phosphorylation of CREB1 protein]; Okadaic Acid inhibits the reaction [resveratrol inhibits the reaction [Colforsin results in increased phosphorylation of CREB1 protein]]; resveratrol inhibits the reaction [Colforsin promotes the reaction [CREB1 protein binds to POU1F1 promoter]]; resveratrol inhibits the reaction [Colforsin results in increased phosphorylation of CREB1 protein]; SIRT1 mutant form inhibits the reaction [resveratrol inhibits the reaction [Colforsin results in increased phosphorylation of CREB1 protein]]; SIRT1 protein inhibits the reaction [Colforsin results in increased phosphorylation of CREB1 protein]; SIRT1 protein mutant form inhibits the reaction [Colforsin results in increased phosphorylation of CREB1 protein]
AKAP13 protein modified form inhibits the reaction [Colforsin results in increased phosphorylation of CREB1 protein]; anandamide inhibits the reaction [Colforsin results in increased phosphorylation of CREB1 protein]; Colforsin inhibits the reaction [anandamide inhibits the reaction [CREB1 protein modified form binds to ABCG2 promoter]]; Colforsin results in increased phosphorylation of and results in increased activity of CREB1 protein
oxophenylarsine inhibits the reaction [Colforsin results in increased activity of CREB1 protein]; oxophenylarsine inhibits the reaction [Colforsin results in increased phosphorylation of CREB1 protein]; RTKI cpd inhibits the reaction [Colforsin results in increased phosphorylation of CREB1 protein]
CTD PMID:10908723 PMID:15522277 PMID:17141199 PMID:17322281 PMID:17460731 More... NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Crebbp CREB binding protein multiple interactions ISO Colforsin promotes the reaction [GCM1 protein binds to CREBBP protein]; CREBBP protein affects the reaction [Colforsin results in increased activity of GCM1 protein] CTD PMID:16166624 NCBI chr10:11,335,551...11,461,888
Ensembl chr10:11,335,953...11,461,888
JBrowse link
G Crem cAMP responsive element modulator increases expression EXP Colforsin results in increased expression of CREM mRNA; Colforsin results in increased expression of CREM mRNA alternative form; Colforsin results in increased expression of CREM protein CTD PMID:8810303 PMID:12791704 NCBI chr17:54,238,889...54,305,989
Ensembl chr17:54,239,030...54,305,989
JBrowse link
G Crh corticotropin releasing hormone multiple interactions
increases secretion
EXP
ISO
CRH protein inhibits the reaction [[Colforsin co-treated with CGB3 protein] results in increased chemical synthesis of Cyclic AMP]; CRH protein inhibits the reaction [[Colforsin co-treated with CGB3 protein] results in increased chemical synthesis of Testosterone]; CRH protein inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]; CRH protein inhibits the reaction [Colforsin results in increased chemical synthesis of Testosterone]
Colforsin results in increased secretion of CRH protein
[perfluorooctane sulfonic acid co-treated with Colforsin] results in increased expression of CRH mRNA
CTD PMID:2153673 PMID:33144174 NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919
JBrowse link
G Crls1 cardiolipin synthase 1 increases expression ISO Colforsin results in increased expression of CRLS1 mRNA CTD PMID:16751804 NCBI chr 3:120,119,822...120,138,674
Ensembl chr 3:120,119,852...120,138,655
JBrowse link
G Cryab crystallin, alpha B multiple interactions EXP Colforsin inhibits the reaction [arsenite results in increased expression of CRYAB protein] CTD PMID:8769853 NCBI chr 8:51,093,441...51,099,161
Ensembl chr 8:51,093,441...51,099,157
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 affects expression
multiple interactions
increases expression
ISO
EXP
Colforsin affects the expression of CYP11A1 mRNA
[Colforsin co-treated with Zearalenone] results in increased expression of CYP11A1 mRNA
Colforsin results in increased expression of CYP11A1 mRNA
[Colforsin co-treated with triptolide] results in decreased expression of CYP11A1 mRNA; Aminoglutethimide inhibits the reaction [Colforsin results in increased expression of CYP11A1 mRNA]; BMP6 protein inhibits the reaction [Colforsin results in increased expression of CYP11A1 mRNA]; Hexachlorocyclohexane inhibits the reaction [Colforsin results in increased expression of CYP11A1 mRNA]; Metyrapone inhibits the reaction [Colforsin results in increased expression of CYP11A1 mRNA]; Valproic Acid affects the reaction [Colforsin affects the expression of CYP11A1 mRNA]
[Atrazine co-treated with Colforsin] results in increased expression of CYP11A1 mRNA; RARRES2 protein inhibits the reaction [Colforsin results in increased expression of CYP11A1 protein]
CTD PMID:14691014 PMID:16935330 PMID:17080404 PMID:18936084 PMID:20726872 More... NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338
JBrowse link
G Cyp11b3 cytochrome P450, family 11, subfamily b, polypeptide 3 increases expression
multiple interactions
increases activity
ISO Colforsin results in increased expression of CYP11B2 mRNA
1-chloro-4-(2,2-dichloro-1-(4-chlorophenyl)ethenyl)-3-(methylsulfonyl)benzene inhibits the reaction [Colforsin results in increased activity of CYP11B1 protein]; 2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene inhibits the reaction [Colforsin results in increased activity of CYP11B1 protein]; Etomidate inhibits the reaction [Colforsin results in increased activity of CYP11B1 protein]
[1-chloro-4-(2,2-dichloro-1-(4-chlorophenyl)ethenyl)-3-(methylsulfonyl)benzene co-treated with Colforsin] affects the expression of CYP11B2 mRNA; [Colforsin co-treated with triptolide] results in decreased expression of CYP11B2 mRNA; Hexachlorocyclohexane inhibits the reaction [Colforsin results in increased expression of CYP11B2 mRNA]; Ketoconazole promotes the reaction [Colforsin results in increased expression of CYP11B2 mRNA]
CTD PMID:16935330 PMID:17080404 PMID:18651133 PMID:19164467 PMID:19900470 More... NCBI chr 7:106,808,559...106,814,048
Ensembl chr 7:106,808,559...106,814,048
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 increases expression
multiple interactions
ISO Colforsin results in increased expression of CYP17A1 mRNA
[Colforsin co-treated with triptolide] results in decreased expression of CYP17A1 mRNA; Apigenin inhibits the reaction [Colforsin results in increased expression of CYP17A1 mRNA]; Hexachlorocyclohexane inhibits the reaction [Colforsin results in increased expression of CYP17A1 mRNA]; Ketoconazole inhibits the reaction [Colforsin results in increased expression of CYP17A1 mRNA]; Metyrapone inhibits the reaction [Colforsin results in increased expression of CYP17A1 mRNA]; TGFB1 protein inhibits the reaction [Colforsin results in increased expression of CYP17A1 mRNA]; Valproic Acid inhibits the reaction [Colforsin results in increased expression of CYP17A1 mRNA]
CTD PMID:15625562 PMID:15886251 PMID:16935330 PMID:17080404 PMID:20726872 More... NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 increases activity
increases expression
multiple interactions
ISO
EXP
Colforsin results in increased activity of CYP19A1 protein
Colforsin results in increased expression of CYP19A1 mRNA
1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Colforsin results in increased expression of CYP19A1 mRNA]; [Colforsin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CYP19A1 mRNA; [Colforsin results in increased activity of CYP19A1 protein] which results in increased abundance of Estradiol; [Colforsin results in increased activity of CYP19A1 protein] which results in increased abundance of Testosterone; Alitretinoin inhibits the reaction [NR5A2 protein promotes the reaction [[Colforsin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CYP19A1 mRNA]]; Aminoglutethimide inhibits the reaction [Colforsin results in increased expression of CYP19A1 mRNA]; Atrazine inhibits the reaction [Colforsin results in increased expression of CYP19A1 mRNA]; BMP6 protein inhibits the reaction [Colforsin results in increased expression of CYP19A1 mRNA]; Hexachlorocyclohexane inhibits the reaction [Colforsin results in increased expression of CYP19A1 mRNA]; mono-(2-ethylhexyl)phthalate inhibits the reaction [Colforsin results in increased expression of CYP19A1 mRNA]; NR4A1 protein inhibits the reaction [Colforsin results in increased expression of CYP19A1 mRNA]; NR4A2 protein inhibits the reaction [Colforsin results in increased expression of CYP19A1 mRNA]; NR4A3 protein inhibits the reaction [Colforsin results in increased expression of CYP19A1 mRNA]; NR5A2 protein promotes the reaction [[Colforsin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CYP19A1 mRNA]; Valproic Acid inhibits the reaction [Colforsin results in increased activity of CYP19A1 protein]; Valproic Acid inhibits the reaction [Colforsin results in increased expression of CYP19A1 mRNA]; ZNF461 protein inhibits the reaction [Colforsin results in increased expression of CYP19A1 mRNA]
RARRES2 protein inhibits the reaction [Colforsin results in increased expression of CYP19A1 protein]
CTD PMID:14691014 PMID:16357189 PMID:16935330 PMID:16996190 PMID:17080404 More... NCBI chr 8:54,553,165...54,580,758
Ensembl chr 8:54,553,165...54,580,758
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
affects expression
EXP
ISO
Colforsin inhibits the reaction [Lipopolysaccharides results in decreased activity of CYP1A1 protein]
Valproic Acid affects the reaction [Colforsin affects the expression of CYP1A1 mRNA]
Colforsin affects the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA]
CTD PMID:1849469 PMID:15710352 PMID:20726872 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions ISO
EXP
Colforsin affects the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]
Colforsin inhibits the reaction [Lipopolysaccharides results in decreased activity of CYP1A2 protein]
CTD PMID:1849469 PMID:15710352 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases expression EXP Colforsin results in increased expression of CYP1B1 mRNA; Colforsin results in increased expression of CYP1B1 protein CTD PMID:7588239 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Cyp2a3 cytochrome P450, family 2, subfamily a, polypeptide 3 increases expression ISO Colforsin results in increased expression of CYP2A5 mRNA CTD PMID:11162586 NCBI chr 1:82,171,914...82,179,980
Ensembl chr 1:82,169,949...82,179,979
JBrowse link
G Dbh dopamine beta-hydroxylase multiple interactions
increases expression
EXP Colforsin inhibits the reaction [Atrazine results in decreased expression of DBH protein]; Colforsin inhibits the reaction [Simazine results in decreased expression of DBH protein]
Colforsin results in increased expression of DBH protein
CTD PMID:14550852 NCBI chr 3:10,488,260...10,505,245
Ensembl chr 3:10,488,260...10,505,248
JBrowse link
G Dct dopachrome tautomerase increases expression ISO Colforsin results in increased expression of DCT mRNA; Colforsin results in increased expression of DCT protein CTD PMID:17460731 PMID:28601556 NCBI chr15:95,062,006...95,100,863
Ensembl chr15:95,062,003...95,100,836
JBrowse link
G Dio2 iodothyronine deiodinase 2 increases activity
multiple interactions
increases expression
ISO
EXP
Colforsin results in increased activity of DIO2 protein
Buthionine Sulfoximine inhibits the reaction [Colforsin results in increased activity of DIO2 protein]; Hydrogen Peroxide inhibits the reaction [Colforsin results in increased activity of DIO2 protein]; Hydrogen Peroxide inhibits the reaction [Colforsin results in increased expression of DIO2 mRNA]; Sodium Selenite inhibits the reaction [Hydrogen Peroxide inhibits the reaction [Colforsin results in increased activity of DIO2 protein]]; U 0126 inhibits the reaction [Hydrogen Peroxide inhibits the reaction [Colforsin results in increased activity of DIO2 protein]]; U 0126 inhibits the reaction [Hydrogen Peroxide inhibits the reaction [Colforsin results in increased expression of DIO2 mRNA]]
CTD PMID:18420745 PMID:19036883 NCBI chr 6:109,665,523...109,679,809
Ensembl chr 6:109,665,523...109,679,809
JBrowse link
G Dio3 iodothyronine deiodinase 3 multiple interactions EXP Colforsin promotes the reaction [Hydrogen Peroxide results in increased expression of DIO3 mRNA] CTD PMID:18420745 NCBI chr 6:129,285,747...129,287,608
Ensembl chr 6:129,285,749...129,286,660
JBrowse link
G Dnm1l dynamin 1-like multiple interactions
decreases expression
ISO PINK1 protein affects the reaction [Colforsin results in decreased expression of DNM1L protein] CTD PMID:24792327 NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482
JBrowse link
G Drd2 dopamine receptor D2 multiple interactions ISO [Quinpirole binds to and results in increased activity of DRD2 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]; epigallocatechin gallate inhibits the reaction [[Quinpirole binds to and results in increased activity of DRD2 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]] CTD PMID:17958328 NCBI chr 8:49,708,903...49,772,888
Ensembl chr 8:49,708,927...49,772,875
JBrowse link
G Dynll2 dynein light chain LC8-type 2 increases expression ISO Colforsin results in increased expression of DYNLL2 mRNA CTD PMID:16751804 NCBI chr10:72,767,035...72,785,824
Ensembl chr10:72,767,035...72,785,805
JBrowse link
G Edn1 endothelin 1 multiple interactions ISO Colforsin inhibits the reaction [EDN1 protein results in increased expression of CALCRL mRNA]; Colforsin inhibits the reaction [EDN1 protein results in increased expression of ICAM2 mRNA] CTD PMID:25194819 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Egf epidermal growth factor multiple interactions ISO [EGF co-treated with Colforsin co-treated with Rotenone] results in increased expression of HSPD1 mRNA; [EGF co-treated with Colforsin co-treated with Rotenone] results in increased expression of SOD1 mRNA; [EGF co-treated with Colforsin co-treated with Rotenone] results in increased expression of SOD1 protein; [EGF co-treated with Colforsin co-treated with Rotenone] results in increased expression of SOD2 mRNA; [EGF co-treated with Colforsin co-treated with Rotenone] results in increased expression of SOD2 protein; Acetylcysteine inhibits the reaction [[EGF co-treated with Colforsin co-treated with Rotenone] results in increased expression of HSPD1 mRNA]; Acetylcysteine inhibits the reaction [[EGF co-treated with Colforsin co-treated with Rotenone] results in increased expression of SOD1 mRNA]; Acetylcysteine inhibits the reaction [[EGF co-treated with Colforsin co-treated with Rotenone] results in increased expression of SOD1 protein]; Acetylcysteine inhibits the reaction [[EGF co-treated with Colforsin co-treated with Rotenone] results in increased expression of SOD2 mRNA]; Acetylcysteine inhibits the reaction [[EGF co-treated with Colforsin co-treated with Rotenone] results in increased expression of SOD2 protein] CTD PMID:32092105 NCBI chr 2:218,219,408...218,302,370
Ensembl chr 2:218,219,415...218,302,064
JBrowse link
G Egr1 early growth response 1 decreases expression
multiple interactions
ISO Colforsin results in decreased expression of EGR1 mRNA; Colforsin results in decreased expression of EGR1 protein
Colforsin inhibits the reaction [Ethanol results in increased expression of EGR1 mRNA]; Colforsin inhibits the reaction [Ethanol results in increased expression of EGR1 protein]; Ethanol inhibits the reaction [Colforsin results in decreased expression of EGR1 mRNA]; Ethanol inhibits the reaction [Colforsin results in decreased expression of EGR1 protein]
CTD PMID:29802914 NCBI chr18:26,463,333...26,465,531
Ensembl chr18:26,462,981...26,466,766
JBrowse link
G Eif2b5 eukaryotic translation initiation factor 2B subunit epsilon increases expression ISO Colforsin results in increased expression of EIF2B5 mRNA CTD PMID:16751804 NCBI chr11:80,394,433...80,404,468
Ensembl chr11:80,394,433...80,404,419
JBrowse link
G Eif5a2 eukaryotic translation initiation factor 5A2 decreases expression ISO Colforsin results in decreased expression of EIF5A2 mRNA CTD PMID:30983542 NCBI chr 2:111,728,587...111,746,087
Ensembl chr 2:111,729,323...111,746,087
JBrowse link
G Ephx1 epoxide hydrolase 1 affects expression
multiple interactions
ISO Colforsin affects the expression of EPHX1 mRNA
Valproic Acid affects the reaction [Colforsin affects the expression of EPHX1 mRNA]
CTD PMID:20726872 NCBI chr13:92,714,315...92,744,124
Ensembl chr13:92,714,315...92,790,235
JBrowse link
G Eps8 epidermal growth factor receptor pathway substrate 8 decreases expression ISO Colforsin results in decreased expression of EPS8 mRNA CTD PMID:15313392 PMID:15967414 NCBI chr 4:170,388,378...170,486,873
Ensembl chr 4:170,388,378...170,486,873
JBrowse link
G Ereg epiregulin increases expression ISO Colforsin results in increased expression of EREG mRNA CTD PMID:15313392 PMID:15474502 PMID:15967414 PMID:20378682 NCBI chr14:17,027,287...17,041,062
Ensembl chr14:17,027,287...17,041,062
JBrowse link
G Ervfrd-1 endogenous retrovirus group FRD member 1, envelope multiple interactions
increases expression
increases secretion
ISO Colforsin promotes the reaction [Benzo(a)pyrene results in increased expression of ERVFRD-1 mRNA]
Colforsin results in increased expression of ERVFRD-1 mRNA; Colforsin results in increased expression of ERVFRD-1 protein
Colforsin results in increased secretion of ERVFRD-1 protein
CTD PMID:24361490 PMID:29679653 PMID:31278978 PMID:33144174 NCBI chr12:22,151,211...22,158,264
Ensembl chr12:22,151,211...22,158,264
JBrowse link
G Esr1 estrogen receptor 1 decreases expression ISO Colforsin results in decreased expression of ESR1 mRNA CTD PMID:31278978 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions
decreases expression
ISO Colforsin inhibits the reaction [ESR2 gene mutant form inhibits the reaction [CGA protein results in increased abundance of Cyclic AMP]]
Colforsin results in decreased expression of ESR2 mRNA
CTD PMID:20378682 PMID:31278978 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
JBrowse link
G Esrra estrogen related receptor, alpha increases expression ISO Colforsin results in increased expression of ESRRA mRNA; Colforsin results in increased expression of ESRRA protein CTD PMID:20351196 NCBI chr 1:204,104,100...204,114,182
Ensembl chr 1:204,104,101...204,114,268
JBrowse link
G Evi5 ecotropic viral integration site 5 increases expression ISO Colforsin results in increased expression of EVI5 mRNA CTD PMID:16751804 NCBI chr14:1,875,601...2,021,678
Ensembl chr14:1,875,647...2,021,678
JBrowse link
G F2 coagulation factor II multiple interactions ISO Colforsin inhibits the reaction [F2 protein results in increased uptake of Manganese] CTD PMID:2125206 NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486
JBrowse link
G F2r coagulation factor II (thrombin) receptor multiple interactions ISO [C186 65 binds to and results in increased activity of F2R protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP] CTD PMID:22207716 NCBI chr 2:26,869,343...26,885,856
Ensembl chr 2:26,868,404...26,885,870
JBrowse link
G F2rl3 F2R like thrombin or trypsin receptor 3 multiple interactions ISO [GYPGKF-NH(2) binds to and results in increased activity of F2RL3 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP] CTD PMID:22207716 NCBI chr16:17,117,441...17,119,434
Ensembl chr16:17,117,441...17,119,472
JBrowse link
G Fads1 fatty acid desaturase 1 increases expression ISO Colforsin results in increased expression of FADS1 mRNA CTD PMID:16751804 NCBI chr 1:206,827,724...206,842,734
Ensembl chr 1:206,827,765...206,842,734
JBrowse link
G Fasn fatty acid synthase multiple interactions ISO [Colforsin co-treated with 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime] results in increased expression of FASN mRNA; [Colforsin co-treated with Leflunomide] results in increased expression of FASN mRNA; [Colforsin co-treated with teriflunomide] results in increased expression of FASN mRNA CTD PMID:30364229 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
JBrowse link
G Fgf10 fibroblast growth factor 10 multiple interactions ISO Colforsin inhibits the reaction [FGF10 protein results in increased phosphorylation of MAPK1 protein]; Colforsin inhibits the reaction [FGF10 protein results in increased phosphorylation of MAPK3 protein] CTD PMID:12533312 PMID:14975937 NCBI chr 2:50,801,897...50,875,428
Ensembl chr 2:50,800,992...50,876,866
JBrowse link
G Fgf2 fibroblast growth factor 2 increases expression ISO Colforsin results in increased expression of FGF2 mRNA; Colforsin results in increased expression of FGF2 protein CTD PMID:10320526 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221
JBrowse link
G Fgf5 fibroblast growth factor 5 decreases expression EXP Colforsin results in decreased expression of FGF5 mRNA CTD PMID:11598998 NCBI chr14:11,325,334...11,346,570
Ensembl chr14:11,325,334...11,345,997
JBrowse link
G Fgf8 fibroblast growth factor 8 increases activity ISO Colforsin results in increased activity of FGF8 protein CTD PMID:15193767 NCBI chr 1:244,584,477...244,590,359
Ensembl chr 1:244,584,652...244,590,359
JBrowse link
G Fgf9 fibroblast growth factor 9 multiple interactions ISO FGF9 protein inhibits the reaction [Colforsin promotes the reaction [IGF1 protein results in increased abundance of Estradiol]]; FGF9 protein inhibits the reaction [IGF1 protein promotes the reaction [Colforsin results in increased abundance of Progesterone]] CTD PMID:22798350 NCBI chr15:32,208,993...32,254,952
Ensembl chr15:32,210,074...32,253,309
JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 increases expression ISO Colforsin results in increased expression of FGFR1 mRNA CTD PMID:10320526 NCBI chr16:66,492,445...66,546,731
Ensembl chr16:66,494,042...66,547,350
JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 increases expression ISO Colforsin results in increased expression of FGFR2 mRNA CTD PMID:10320526 NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626
JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 multiple interactions ISO Colforsin promotes the reaction [Dexamethasone results in increased expression of FKBP5 mRNA] CTD PMID:19255438 NCBI chr20:6,457,207...6,575,404
Ensembl chr20:6,457,216...6,541,674
JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 increases expression ISO Colforsin results in increased expression of FLT1 mRNA CTD PMID:33144174 NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626
JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit increases expression EXP Colforsin results in increased expression of FOSB mRNA; Colforsin results in increased expression of FOSB protein CTD PMID:17324382 NCBI chr 1:78,954,312...78,961,492
Ensembl chr 1:78,954,115...78,961,465
JBrowse link
G Fshb follicle stimulating hormone subunit beta increases expression EXP Colforsin results in increased expression of FSHB mRNA; Colforsin results in increased expression of FSHB protein CTD PMID:8404651 NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370
JBrowse link
G Fst follistatin multiple interactions ISO FST protein inhibits the reaction [BMP6 protein inhibits the reaction [Colforsin results in increased secretion of Progesterone]]; FST protein inhibits the reaction [INHBA protein inhibits the reaction [Colforsin results in increased secretion of Progesterone]] CTD PMID:18936084 NCBI chr 2:46,123,260...46,130,584
Ensembl chr 2:46,123,439...46,130,571
JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 multiple interactions EXP
ISO
[Dexamethasone co-treated with Colforsin] results in increased expression of G6PC1 mRNA
Colforsin inhibits the reaction [Leflunomide results in increased expression of G6PC1 mRNA]; Colforsin inhibits the reaction [teriflunomide results in increased expression of G6PC1 mRNA]
CTD PMID:18972406 PMID:30364229 NCBI chr10:86,307,400...86,318,766 JBrowse link
G Gabra1 gamma-aminobutyric acid type A receptor subunit alpha 1 increases expression EXP Colforsin results in increased expression of GABRA1 CTD PMID:9147380 NCBI chr10:26,595,151...26,650,611
Ensembl chr10:26,595,160...26,650,864
JBrowse link
G Gabra6 gamma-aminobutyric acid type A receptor subunit alpha6 decreases expression EXP Colforsin results in decreased expression of GABRA6 CTD PMID:9147380 NCBI chr10:26,810,411...26,825,768
Ensembl chr10:26,810,423...26,825,769
JBrowse link
G Gas6 growth arrest specific 6 decreases expression ISO Colforsin results in decreased expression of GAS6 mRNA CTD PMID:15313392 NCBI chr16:76,045,430...76,075,904
Ensembl chr16:76,045,426...76,075,904
JBrowse link
G Gast gastrin multiple interactions
increases secretion
ISO
EXP
Calcium promotes the reaction [Colforsin results in increased secretion of GAST protein]; Nitrendipine inhibits the reaction [Colforsin results in increased secretion of GAST protein]
2',5'-dideoxyadenosine inhibits the reaction [Colforsin results in increased secretion of GAST protein]
CTD PMID:9277405 PMID:19208342 NCBI chr10:85,264,832...85,269,393
Ensembl chr10:85,264,832...85,267,496
JBrowse link
G Gcg glucagon multiple interactions
increases secretion
EXP Colforsin promotes the reaction [Pyruvic Acid results in increased secretion of GCG protein]
Colforsin results in increased secretion of GCG protein
CTD PMID:15919803 NCBI chr 3:47,113,914...47,122,929
Ensembl chr 3:47,113,914...47,122,929
JBrowse link
G Gcm1 glial cells missing transcription factor 1 multiple interactions
decreases expression
ISO Colforsin promotes the reaction [GCM1 protein binds to CREBBP protein]; Colforsin results in increased acetylation of and results in increased activity of GCM1 protein; CREBBP protein affects the reaction [Colforsin results in increased activity of GCM1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Colforsin results in increased activity of GCM1 protein]; trichostatin A promotes the reaction [Colforsin results in increased acetylation of and results in increased activity of GCM1 protein]
Colforsin results in decreased expression of GCM1 mRNA
CTD PMID:16166624 PMID:31278978 NCBI chr 8:78,925,687...78,938,924
Ensembl chr 8:78,925,687...78,938,924
JBrowse link
G Gh1 growth hormone 1 increases secretion
multiple interactions
ISO
EXP
Colforsin results in increased secretion of GH1 protein
GH1 protein promotes the reaction [Colforsin results in increased metabolism of Lipids]
CTD PMID:14981226 PMID:19952226 NCBI chr10:91,228,102...91,230,079
Ensembl chr10:91,228,103...91,230,078
JBrowse link
G Gli1 GLI family zinc finger 1 decreases expression ISO Colforsin results in decreased expression of GLI1 mRNA; Colforsin results in decreased expression of GLI1 protein CTD PMID:30983542 NCBI chr 7:63,156,926...63,169,579
Ensembl chr 7:63,156,926...63,169,251
JBrowse link
G Gli2 GLI family zinc finger 2 multiple interactions EXP Colforsin inhibits the reaction [Carbon Tetrachloride results in increased expression of GLI2 mRNA] CTD PMID:27590029 NCBI chr13:29,946,809...30,163,901
Ensembl chr13:29,946,809...30,163,574
JBrowse link
G Gnai3 G protein subunit alpha i3 increases expression ISO Colforsin results in increased expression of GNAI3 mRNA CTD PMID:16751804 NCBI chr 2:195,742,765...195,780,720
Ensembl chr 2:195,742,642...195,780,742
JBrowse link
G Gpbar1 G protein-coupled bile acid receptor 1 multiple interactions ISO [Colforsin binds to and results in increased activity of GPBAR1 protein] which results in increased abundance of Cyclic AMP; Colforsin binds to and results in increased activity of GPBAR1 protein CTD PMID:17963371 NCBI chr 9:75,862,151...75,863,140
Ensembl chr 9:75,860,677...75,863,168
JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 increases phosphorylation
multiple interactions
EXP Colforsin results in increased phosphorylation of GRIN1 protein
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Colforsin results in increased phosphorylation of GRIN1 protein]
CTD PMID:14622123 NCBI chr 3:8,103,680...8,130,603
Ensembl chr 3:8,103,680...8,130,603
JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B multiple interactions
increases expression
EXP N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Colforsin results in increased expression of GRIN2B protein]
Colforsin results in increased expression of GRIN2B mRNA; Colforsin results in increased expression of GRIN2B protein
CTD PMID:20067577 NCBI chr 4:168,580,824...169,044,110
Ensembl chr 4:168,599,546...169,042,279
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions EXP Colforsin results in increased phosphorylation of and results in decreased activity of GSK3B protein CTD PMID:15950778 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Hamp hepcidin antimicrobial peptide affects expression
multiple interactions
ISO Colforsin affects the expression of HAMP mRNA
Colforsin inhibits the reaction [IL6 protein results in increased expression of HAMP mRNA]
CTD PMID:25633564 NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891
JBrowse link
G Hcar2 hydroxycarboxylic acid receptor 2 multiple interactions ISO [3-Hydroxybutyric Acid results in increased activity of HCAR2 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]; [Niacin results in increased activity of HCAR2 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]; [Nicotinic Acids binds to and results in increased activity of HCAR2 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]; Pertussis Toxin inhibits the reaction [[Nicotinic Acids binds to and results in increased activity of HCAR2 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]] CTD PMID:17124637 PMID:19223991 NCBI chr12:32,726,334...32,727,416
Ensembl chr12:32,726,184...32,728,504
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase affects expression
increases expression
multiple interactions
ISO Colforsin affects the expression of HMGCR mRNA
Colforsin results in increased expression of HMGCR mRNA
[Colforsin co-treated with Ketoconazole] results in decreased expression of HMGCR mRNA; [Colforsin co-treated with triptolide] results in decreased expression of HMGCR mRNA; AR protein promotes the reaction [Colforsin results in increased expression of HMGCR protein]; Colforsin inhibits the reaction [Caffeine results in increased expression of HMGCR mRNA]; Valproic Acid affects the reaction [Colforsin affects the expression of HMGCR mRNA]
CTD PMID:16751804 PMID:16935330 PMID:20726872 PMID:30825513 PMID:31557376 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 multiple interactions ISO Colforsin inhibits the reaction [Caffeine results in increased expression of HMGCS1 mRNA] CTD PMID:30825513 NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100
JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
ISO
EXP
Colforsin results in increased expression of HMOX1 protein
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Colforsin results in increased expression of HMOX1 protein]
Colforsin results in increased expression of HMOX1 mRNA; Colforsin results in increased expression of HMOX1 protein
CTD PMID:15179140 PMID:16439612 PMID:19483313 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hnrnpa1 heterogeneous nuclear ribonucleoprotein A1 multiple interactions EXP HNRNPA1 mutant form inhibits the reaction [Colforsin affects the splicing of RUNX1 exon]; HNRNPA1 mutant form inhibits the reaction [Colforsin affects the splicing of SNAP25 exon] CTD PMID:22684629 NCBI chr 7:134,375,318...134,381,610
Ensembl chr 7:134,375,150...134,381,609
JBrowse link
G Hnrnpk heterogeneous nuclear ribonucleoprotein K multiple interactions EXP Colforsin promotes the reaction [HNRNPK protein binds to SNAP25 exon] CTD PMID:22684629 NCBI chr17:6,262,936...6,275,001
Ensembl chr17:6,262,998...6,274,997
JBrowse link
G Hrh2 histamine receptor H 2 multiple interactions ISO Dimaprit inhibits the reaction [HRH2 protein promotes the reaction [Colforsin results in increased abundance of Cyclic AMP]]; HRH2 protein promotes the reaction [Colforsin results in increased abundance of Cyclic AMP] CTD PMID:9187264 NCBI chr17:10,368,355...10,407,791
Ensembl chr17:10,368,298...10,407,631
JBrowse link
G Hrh3 histamine receptor H3 multiple interactions EXP [imetit results in increased activity of HRH3 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]; ciproxifan inhibits the reaction [[imetit results in increased activity of HRH3 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]]; Pertussis Toxin inhibits the reaction [[imetit results in increased activity of HRH3 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]]; thioperamide inhibits the reaction [[imetit results in increased activity of HRH3 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]] CTD PMID:21276809 NCBI chr 3:167,191,551...167,196,642
Ensembl chr 3:167,191,558...167,196,642
JBrowse link
G Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 multiple interactions
increases expression
ISO Colforsin inhibits the reaction [1,7-dimethylxanthine results in decreased expression of and results in decreased activity of HSD11B2 protein]; Colforsin inhibits the reaction [1,7-dimethylxanthine results in decreased expression of HSD11B2 mRNA]; Colforsin inhibits the reaction [Caffeine results in decreased expression of and results in decreased activity of HSD11B2 protein]; Colforsin inhibits the reaction [Caffeine results in decreased expression of HSD11B2 mRNA]; Colforsin inhibits the reaction [Ethanol results in decreased expression of HSD11B2 mRNA]; Colforsin inhibits the reaction [Ethanol results in decreased expression of HSD11B2 protein]; Ethanol inhibits the reaction [Colforsin results in increased expression of HSD11B2 mRNA]; Ethanol inhibits the reaction [Colforsin results in increased expression of HSD11B2 protein]
Colforsin results in increased expression of HSD11B2 mRNA; Colforsin results in increased expression of HSD11B2 protein
CTD PMID:22701600 PMID:24361490 PMID:29802914 PMID:33144174 NCBI chr19:33,397,656...33,402,899
Ensembl chr19:33,397,656...33,402,899
JBrowse link
G Hsd17b1 hydroxysteroid (17-beta) dehydrogenase 1 affects expression
increases expression
multiple interactions
ISO Colforsin affects the expression of HSD17B1 mRNA
Colforsin results in increased expression of HSD17B1 mRNA
[Colforsin co-treated with Aminoglutethimide] results in decreased expression of HSD17B1 mRNA; [Colforsin co-treated with Metyrapone] results in decreased expression of HSD17B1 mRNA; Valproic Acid affects the reaction [Colforsin affects the expression of HSD17B1 mRNA]
CTD PMID:16935330 PMID:20726872 PMID:22446829 NCBI chr10:86,009,728...86,011,928
Ensembl chr10:86,009,728...86,011,927
JBrowse link
G Hsd17b3 hydroxysteroid (17-beta) dehydrogenase 3 increases expression ISO Colforsin results in increased expression of HSD17B3 mRNA CTD PMID:22461451 NCBI chr17:1,027,229...1,058,554
Ensembl chr17:1,027,229...1,058,554
JBrowse link
G Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 affects expression
multiple interactions
increases expression
ISO Colforsin affects the expression of HSD17B4 mRNA
Aminoglutethimide inhibits the reaction [Colforsin results in increased expression of HSD17B4 mRNA]; Ketoconazole promotes the reaction [Colforsin results in increased expression of HSD17B4 mRNA]; Valproic Acid affects the reaction [Colforsin affects the expression of HSD17B4 mRNA]
CTD PMID:16935330 PMID:20726872 PMID:22446829 NCBI chr18:43,328,903...43,417,950
Ensembl chr18:43,328,824...43,417,952
JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 multiple interactions ISO BMP6 protein inhibits the reaction [Colforsin results in increased expression of HSD3B1 mRNA] CTD PMID:18936084 NCBI chr 2:186,169,864...186,175,984
Ensembl chr 2:186,169,863...186,175,999
JBrowse link
G Hsd3b2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 increases expression
multiple interactions
ISO Colforsin results in increased expression of HSD3B2 mRNA
[Colforsin co-treated with Ketoconazole] results in decreased expression of HSD3B2 mRNA; [Colforsin co-treated with Metyrapone] results in decreased expression of HSD3B2 mRNA; [Colforsin co-treated with triptolide] results in decreased expression of HSD3B2 mRNA; Apigenin inhibits the reaction [Colforsin results in increased expression of HSD3B2 mRNA]; daidzein inhibits the reaction [Colforsin results in increased expression of HSD3B2 mRNA]; Hexachlorocyclohexane inhibits the reaction [Colforsin results in increased expression of HSD3B2 mRNA]; Valproic Acid inhibits the reaction [Colforsin results in increased expression of HSD3B2 mRNA]
CTD PMID:16935330 PMID:17080404 PMID:20726872 PMID:21256172 PMID:22446829 More... NCBI chr 2:186,095,897...186,105,354
Ensembl chr 2:186,095,897...186,101,852
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 increases response to substance ISO HSPA5 protein results in increased susceptibility to Colforsin CTD PMID:22912664 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 multiple interactions ISO [EGF co-treated with Colforsin co-treated with Rotenone] results in increased expression of HSPD1 mRNA; Acetylcysteine inhibits the reaction [[EGF co-treated with Colforsin co-treated with Rotenone] results in increased expression of HSPD1 mRNA] CTD PMID:32092105 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662
JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A multiple interactions ISO [JB-788 binds to and results in increased activity of HTR1A protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]; Arachidonic Acid metabolite inhibits the reaction [HTR1A protein inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]]; HTR1A protein inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]; Melitten inhibits the reaction [HTR1A protein inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]] CTD PMID:11356925 PMID:20580787 NCBI chr 2:36,694,174...36,695,442
Ensembl chr 2:36,694,174...36,695,442
JBrowse link
G Htr1b 5-hydroxytryptamine receptor 1B multiple interactions ISO HTR1B affects the reaction [almotriptan inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]] CTD PMID:11134654 NCBI chr 8:82,513,572...82,534,892
Ensembl chr 8:82,517,360...82,534,549
JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A multiple interactions EXP Colforsin inhibits the reaction [N-(piperidin-1-yl)-1-(2,4-dichlorophenyl)-1,4-dihydro-6-methylindeno(1,2-c)pyrazole-3-carboxamide results in increased expression of HTR2A mRNA] CTD PMID:22791651 NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928
JBrowse link
G Htr7 5-hydroxytryptamine receptor 7 multiple interactions ISO [Bromocriptine binds to and results in decreased activity of HTR7 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]; [Lisuride binds to and results in decreased activity of HTR7 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]; [Metergoline binds to and results in decreased activity of HTR7 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]; [Methiothepin binds to and results in decreased activity of HTR7 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]; [Paliperidone Palmitate binds to and results in decreased activity of HTR7 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]; [Risperidone binds to and results in decreased activity of HTR7 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP] CTD PMID:19509219 NCBI chr 1:233,636,442...233,761,063
Ensembl chr 1:233,636,452...233,760,626
JBrowse link
G Iapp islet amyloid polypeptide increases expression EXP Colforsin results in increased expression of IAPP mRNA CTD PMID:9142872 NCBI chr 4:175,237,013...175,244,373
Ensembl chr 4:175,237,115...175,242,920
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO Colforsin inhibits the reaction [Reactive Oxygen Species results in increased expression of ICAM1 mRNA]; Colforsin inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA] CTD PMID:10495789 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Icam2 intercellular adhesion molecule 2 multiple interactions ISO Colforsin inhibits the reaction [EDN1 protein results in increased expression of ICAM2 mRNA] CTD PMID:25194819 NCBI chr10:91,308,608...91,319,536
Ensembl chr10:91,308,538...91,315,293
JBrowse link
G Ier3 immediate early response 3 affects response to substance ISO IER3 protein affects the susceptibility to Colforsin CTD PMID:20713914 NCBI chr20:2,928,378...2,929,582
Ensembl chr20:2,928,378...2,929,583
JBrowse link
G Ifng interferon gamma multiple interactions ISO Colforsin inhibits the reaction [IFNG protein promotes the reaction [decitabine results in increased expression of PLA2G2A protein]] CTD PMID:18953428 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions ISO Colforsin promotes the reaction [IGF1 protein results in increased abundance of Estradiol]; FGF9 protein inhibits the reaction [Colforsin promotes the reaction [IGF1 protein results in increased abundance of Estradiol]]; FGF9 protein inhibits the reaction [IGF1 protein promotes the reaction [Colforsin results in increased abundance of Progesterone]]; IGF1 protein promotes the reaction [Colforsin results in increased abundance of Progesterone] CTD PMID:22798350 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 increases expression
multiple interactions
ISO Colforsin results in increased expression of IGFBP1
[Medroxyprogesterone Acetate co-treated with Estradiol co-treated with Colforsin] results in increased expression of IGFBP1 mRNA
CTD PMID:12093828 PMID:31154070 NCBI chr14:82,047,415...82,052,482
Ensembl chr14:82,047,415...82,052,482
JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta multiple interactions ISO Colforsin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of IKBKB mRNA] CTD PMID:17407152 NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250
JBrowse link
G Il10 interleukin 10 decreases expression ISO Colforsin results in decreased expression of IL10 protein CTD PMID:10996031 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il11 interleukin 11 increases expression ISO Colforsin results in increased expression of IL11 mRNA CTD PMID:22138297 NCBI chr 1:69,069,829...69,076,129
Ensembl chr 1:69,068,137...69,076,129
JBrowse link
G Il12a interleukin 12A decreases expression ISO Colforsin results in decreased expression of IL12A protein CTD PMID:10996031 NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734
JBrowse link
G Il12b interleukin 12B multiple interactions
increases expression
ISO Colforsin inhibits the reaction [oxophenylarsine promotes the reaction [Lipopolysaccharides results in increased expression of IL12B protein]]; Colforsin results in increased expression of [IL12B protein binds to IL23A protein]
Colforsin results in increased expression of IL12B protein
CTD PMID:10996031 PMID:15180965 PMID:20512473 NCBI chr10:28,888,832...28,903,796
Ensembl chr10:28,893,008...28,902,903
JBrowse link
G Il13 interleukin 13 decreases secretion
decreases expression
ISO Colforsin results in decreased secretion of IL13 protein
Colforsin results in decreased expression of IL13 mRNA
CTD PMID:16083514 NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO
EXP
Colforsin promotes the reaction [IL1B protein results in increased expression of PTGS2 protein]
Colforsin inhibits the reaction [Carbon Tetrachloride results in increased expression of IL1B protein]
CTD PMID:11112151 PMID:27590029 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il23a interleukin 23 subunit alpha increases expression
multiple interactions
ISO Colforsin results in increased expression of IL23A protein
Colforsin results in increased expression of [IL12B protein binds to IL23A protein]
CTD PMID:15180965 NCBI chr 7:721,809...723,923
Ensembl chr 7:721,809...723,923
JBrowse link
G Il2ra interleukin 2 receptor subunit alpha decreases expression ISO Colforsin results in decreased expression of IL2RA protein CTD PMID:1709825 NCBI chr17:66,849,974...66,898,665
Ensembl chr17:66,849,974...66,898,697
JBrowse link
G Il4 interleukin 4 multiple interactions ISO Colforsin inhibits the reaction [Itraconazole results in decreased expression of IL4 mRNA]; Colforsin inhibits the reaction [Itraconazole results in decreased secretion of IL4 protein]; Colforsin inhibits the reaction [Ketoconazole results in decreased expression of IL4 mRNA]; Colforsin inhibits the reaction [Ketoconazole results in decreased secretion of IL4 protein]; Colforsin inhibits the reaction [Miconazole results in decreased expression of IL4 mRNA]; Colforsin inhibits the reaction [Miconazole results in decreased secretion of IL4 protein]; Colforsin inhibits the reaction [terbinafine results in decreased expression of IL4 mRNA]; Colforsin inhibits the reaction [terbinafine results in decreased secretion of IL4 protein]; Colforsin inhibits the reaction [Tolnaftate results in decreased expression of IL4 mRNA]; Colforsin inhibits the reaction [Tolnaftate results in decreased secretion of IL4 protein] CTD PMID:11886533 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Il5 interleukin 5 multiple interactions ISO Colforsin inhibits the reaction [Itraconazole results in decreased expression of IL5 mRNA]; Colforsin inhibits the reaction [Itraconazole results in decreased secretion of IL5 protein]; Colforsin inhibits the reaction [Ketoconazole results in decreased expression of IL5 mRNA]; Colforsin inhibits the reaction [Ketoconazole results in decreased secretion of IL5 protein]; Colforsin inhibits the reaction [Miconazole results in decreased expression of IL5 mRNA]; Colforsin inhibits the reaction [Miconazole results in decreased secretion of IL5 protein]; Colforsin inhibits the reaction [terbinafine results in decreased expression of IL5 mRNA]; Colforsin inhibits the reaction [terbinafine results in decreased secretion of IL5 protein]; Colforsin inhibits the reaction [Tolnaftate results in decreased expression of IL5 mRNA]; Colforsin inhibits the reaction [Tolnaftate results in decreased secretion of IL5 protein] CTD PMID:11886533 NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213
JBrowse link
G Il6 interleukin 6 multiple interactions
increases secretion
EXP
ISO
Colforsin inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]
Colforsin inhibits the reaction [IL6 protein results in increased expression of HAMP mRNA]; Colforsin promotes the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]; Colforsin promotes the reaction [TNF protein results in increased expression of IL6 mRNA]
Colforsin results in increased secretion of IL6 protein
oxophenylarsine inhibits the reaction [Colforsin results in increased secretion of IL6 protein]
CTD PMID:17141199 PMID:20388727 PMID:21803157 PMID:24771768 PMID:25633564 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Inhba inhibin subunit beta A multiple interactions ISO FST protein inhibits the reaction [INHBA protein inhibits the reaction [Colforsin results in increased secretion of Progesterone]]; INHBA protein inhibits the reaction [Colforsin results in increased secretion of Progesterone] CTD PMID:18936084 NCBI chr17:49,091,635...49,111,573
Ensembl chr17:49,095,920...49,108,982
JBrowse link
G Insig1 insulin induced gene 1 multiple interactions
increases expression
ISO AR protein promotes the reaction [Colforsin results in increased expression of INSIG1 protein]
Colforsin results in increased expression of INSIG1 mRNA; Colforsin results in increased expression of INSIG1 protein
CTD PMID:16751804 NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952
JBrowse link
G Irs1 insulin receptor substrate 1 multiple interactions ISO Colforsin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of IRS1 mRNA] CTD PMID:17407152 NCBI chr 9:83,552,964...83,605,797
Ensembl chr 9:83,548,944...83,606,122
JBrowse link
G Itga1 integrin subunit alpha 1 affects response to substance EXP ITGA1 protein affects the susceptibility to Colforsin CTD PMID:15836982 NCBI chr 2:46,646,125...46,812,237
Ensembl chr 2:46,653,193...46,812,238
JBrowse link
G Itga3 integrin subunit alpha 3 affects response to substance EXP ITGA3 protein affects the susceptibility to Colforsin CTD PMID:15836982 NCBI chr10:79,990,160...80,022,206
Ensembl chr10:79,990,161...80,022,118
JBrowse link
G Itgb1 integrin subunit beta 1 affects response to substance EXP ITGB1 protein affects the susceptibility to Colforsin CTD PMID:15836982 NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195
JBrowse link
G Itgb5 integrin subunit beta 5 increases expression ISO Colforsin results in increased expression of ITGB5 mRNA CTD PMID:16751804 NCBI chr11:66,828,428...66,944,231
Ensembl chr11:66,829,285...66,944,472
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 multiple interactions ISO [[Colforsin co-treated with 1-Methyl-3-isobutylxanthine] results in increased activity of [ADRB1 protein binds to ADRB2 protein]] affects the reaction [KCNH2 protein results in increased transport of Potassium] CTD PMID:19419905 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008
JBrowse link
G Lep leptin decreases expression
decreases secretion
multiple interactions
ISO Colforsin results in decreased expression of LEP mRNA
Colforsin results in decreased secretion of LEP protein
Colforsin inhibits the reaction [Caffeine results in decreased expression of LEP mRNA]
CTD PMID:9002984 PMID:26367767 PMID:27381457 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link
G Lhb luteinizing hormone subunit beta increases expression
multiple interactions
EXP Colforsin results in increased expression of LHB protein
[Colforsin co-treated with CGB3 protein] results in increased chemical synthesis of Cyclic AMP; [Colforsin co-treated with CGB3 protein] results in increased chemical synthesis of Testosterone; CRH protein inhibits the reaction [[Colforsin co-treated with CGB3 protein] results in increased chemical synthesis of Cyclic AMP]; CRH protein inhibits the reaction [[Colforsin co-treated with CGB3 protein] results in increased chemical synthesis of Testosterone]; Tetradecanoylphorbol Acetate inhibits the reaction [[Colforsin co-treated with CGB3 protein] results in increased chemical synthesis of Cyclic AMP]; Tetradecanoylphorbol Acetate inhibits the reaction [[Colforsin co-treated with CGB3 protein] results in increased chemical synthesis of Testosterone]
CTD PMID:2153673 PMID:8404651 NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972
Ensembl chr 1:95,900,984...95,901,972
JBrowse link
G Lhcgr luteinizing hormone/choriogonadotropin receptor multiple interactions ISO [Colforsin co-treated with deoxynivalenol] results in increased expression of LHCGR mRNA; [Colforsin co-treated with Zearalenone] results in increased expression of LHCGR mRNA CTD PMID:26783879 NCBI chr 6:5,661,871...5,728,109
Ensembl chr 6:5,661,871...5,724,521
JBrowse link
G Lipe lipase E, hormone sensitive type affects localization EXP Colforsin affects the localization of LIPE protein CTD PMID:11160373 NCBI chr 1:80,965,612...80,984,313
Ensembl chr 1:80,965,627...80,984,310
JBrowse link
G Lpl lipoprotein lipase increases expression EXP Colforsin results in increased expression of LPL mRNA CTD PMID:9032464 NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249
JBrowse link
G Ltbp2 latent transforming growth factor beta binding protein 2 decreases expression ISO Colforsin results in decreased expression of LTBP2 mRNA CTD PMID:15313392 NCBI chr 6:104,429,947...104,530,498
Ensembl chr 6:104,429,947...104,526,208
JBrowse link
G Ltc4s leukotriene C4 synthase decreases secretion ISO Colforsin results in decreased secretion of LTC4S protein CTD PMID:16083514 NCBI chr10:34,560,476...34,562,790
Ensembl chr10:34,560,360...34,562,651
JBrowse link
G Lyz2 lysozyme 2 multiple interactions
decreases secretion
increases secretion
ISO 3-((3-trifluoromethyl)phenyl)-5-((3-carboxyphenyl)methylene)-2-thioxo-4-thiazolidinone inhibits the reaction [Colforsin results in increased secretion of LYZ protein]; [Thapsigargin co-treated with Colforsin] results in increased secretion of LYZ protein
Colforsin results in decreased secretion of LYZ protein
CTD PMID:15194485 PMID:15234967 NCBI chr 7:52,906,810...52,912,154
Ensembl chr 7:52,906,811...52,912,106
JBrowse link
G Maf MAF bZIP transcription factor decreases expression ISO Colforsin results in decreased expression of MAF mRNA CTD PMID:16751804 NCBI chr19:43,353,867...43,713,162
Ensembl chr19:43,360,342...43,712,365
JBrowse link
G Map7 microtubule-associated protein 7 increases expression ISO Colforsin results in increased expression of MAP7 mRNA CTD PMID:16751804 NCBI chr 1:14,910,433...15,037,574
Ensembl chr 1:14,910,551...15,037,574
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation
increases activity
ISO
EXP
Colforsin inhibits the reaction [FGF10 protein results in increased phosphorylation of MAPK1 protein]; Colforsin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK1 protein]; Colforsin inhibits the reaction [Shiga Toxin results in increased activity of MAPK1 protein]
1-Methyl-3-isobutylxanthine promotes the reaction [Colforsin inhibits the reaction [Testosterone results in increased phosphorylation of MAPK1 protein]]; Colforsin inhibits the reaction [Testosterone results in increased phosphorylation of MAPK1 protein]; Colforsin promotes the reaction [1-Methyl-3-isobutylxanthine inhibits the reaction [Testosterone results in increased phosphorylation of MAPK1 protein]]; Colforsin promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Colforsin promotes the reaction [1-Methyl-3-isobutylxanthine inhibits the reaction [Testosterone results in increased phosphorylation of MAPK1 protein]]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Colforsin results in increased phosphorylation of MAPK1 protein]; Propranolol inhibits the reaction [Colforsin results in increased activity of MAPK1 protein]; Tetradecanoylphorbol Acetate promotes the reaction [Colforsin results in increased phosphorylation of MAPK1 protein]
CTD PMID:11093795 PMID:11675405 PMID:12533312 PMID:14975937 PMID:15385614 More... NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation
increases activity
multiple interactions
ISO
EXP
Colforsin results in increased phosphorylation of MAPK3 protein
Colforsin results in increased activity of MAPK3 protein
1-Methyl-3-isobutylxanthine promotes the reaction [Colforsin inhibits the reaction [Testosterone results in increased phosphorylation of MAPK3 protein]]; Colforsin inhibits the reaction [Testosterone results in increased phosphorylation of MAPK3 protein]; Colforsin promotes the reaction [1-Methyl-3-isobutylxanthine inhibits the reaction [Testosterone results in increased phosphorylation of MAPK3 protein]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Colforsin promotes the reaction [1-Methyl-3-isobutylxanthine inhibits the reaction [Testosterone results in increased phosphorylation of MAPK3 protein]]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Colforsin results in increased phosphorylation of MAPK3 protein]; Propranolol inhibits the reaction [Colforsin results in increased activity of MAPK3 protein]
Colforsin inhibits the reaction [FGF10 protein results in increased phosphorylation of MAPK3 protein]; Colforsin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK3 protein]; Colforsin inhibits the reaction [Shiga Toxin results in increased activity of MAPK3 protein]
CTD PMID:11093795 PMID:11675405 PMID:12533312 PMID:14975937 PMID:15385614 More... NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mc2r melanocortin 2 receptor multiple interactions
increases expression
ISO Valproic Acid inhibits the reaction [Colforsin results in increased expression of MC2R mRNA] CTD PMID:20726872 PMID:25765474 NCBI chr18:62,001,980...62,015,567
Ensembl chr18:62,004,948...62,015,488
JBrowse link
G Med28 mediator complex subunit 28 increases expression ISO Colforsin results in increased expression of MED28 mRNA CTD PMID:16751804 NCBI chr14:65,594,785...65,603,583
Ensembl chr14:65,594,647...65,603,583
JBrowse link
G Mir190 microRNA 190 multiple interactions ISO Colforsin inhibits the reaction [[carvedilol co-treated with ARRB1 protein] results in increased expression of MIR190A mRNA] CTD PMID:24334028 NCBI chr 8:67,850,987...67,851,071 JBrowse link
G Mitf melanocyte inducing transcription factor increases expression ISO Colforsin results in increased expression of MITF mRNA; Colforsin results in increased expression of MITF protein CTD PMID:17460731 PMID:28601556 NCBI chr 4:130,409,020...130,621,145
Ensembl chr 4:130,409,217...130,621,145
JBrowse link
G Mmp16 matrix metallopeptidase 16 increases expression ISO Colforsin results in increased expression of MMP16 mRNA CTD PMID:16751804 NCBI chr 5:31,312,280...31,556,276
Ensembl chr 5:31,312,280...31,548,388
JBrowse link
G Mterf4 mitochondrial transcription termination factor 4 decreases expression ISO Colforsin results in decreased expression of MTERF4 mRNA CTD PMID:16751804 NCBI chr 9:93,834,162...93,838,838
Ensembl chr 9:93,834,144...93,838,864
JBrowse link
G Muc4 mucin 4, cell surface associated increases expression ISO Colforsin results in increased expression of MUC4 protein CTD PMID:28049186 NCBI chr11:68,008,245...68,053,229 JBrowse link
G Myh7 myosin heavy chain 7 multiple interactions EXP Colforsin inhibits the reaction [Dinoprostone results in increased expression of MYH7 protein]; Colforsin inhibits the reaction [Phenylephrine results in increased expression of MYH7 mRNA] CTD PMID:18851973 NCBI chr15:28,446,550...28,469,888
Ensembl chr15:28,446,550...28,468,217
JBrowse link
G Nav1 neuron navigator 1 decreases expression ISO Colforsin results in decreased expression of NAV1 mRNA CTD PMID:16751804 NCBI chr13:46,866,972...47,119,368
Ensembl chr13:46,873,689...47,126,449
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO Colforsin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of NFKB1 mRNA] CTD PMID:17407152 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Ngf nerve growth factor multiple interactions
increases expression
EXP [Colforsin results in increased abundance of Cyclic AMP] which results in increased expression of NGF mRNA
Colforsin results in increased expression of NGF mRNA
CTD PMID:2174743 PMID:2853697 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452
JBrowse link
G Ngly1 N-glycanase 1 increases expression ISO Colforsin results in increased expression of NGLY1 mRNA CTD PMID:16751804 NCBI chr15:9,153,738...9,210,228
Ensembl chr15:9,153,738...9,204,630
JBrowse link
G Nmu neuromedin U increases expression EXP Colforsin results in increased expression of NMU mRNA CTD PMID:23423171 NCBI chr14:31,844,564...31,872,196
Ensembl chr14:31,844,728...31,872,192
JBrowse link
G Nppa natriuretic peptide A multiple interactions EXP Colforsin inhibits the reaction [Dinoprostone results in increased expression of NPPA protein]; Colforsin inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA] CTD PMID:11470465 PMID:18851973 NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351
JBrowse link
G Nr0b1 nuclear receptor subfamily 0, group B, member 1 decreases expression
multiple interactions
ISO Colforsin results in decreased expression of NR0B1 mRNA
Valproic Acid inhibits the reaction [Colforsin results in decreased expression of NR0B1 mRNA]
CTD PMID:20726872 NCBI chr  X:50,756,886...50,761,014
Ensembl chr  X:50,756,886...50,761,011
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity
decreases expression
EXP
ISO
Colforsin results in increased activity of NR1I2 protein
Colforsin results in decreased expression of NR1I2 mRNA
CTD PMID:27732639 PMID:29933105 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 increases activity ISO Colforsin results in increased activity of NR3C1 protein CTD PMID:19255438 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 increases expression
multiple interactions
ISO Colforsin results in increased expression of NR4A1 mRNA; Colforsin results in increased expression of NR4A1 protein
[Colforsin co-treated with deoxynivalenol] results in increased expression of NR4A1 mRNA; Colforsin promotes the reaction [Zearalenone results in increased expression of NR4A1 mRNA]; NR4A1 protein inhibits the reaction [Ryanodine inhibits the reaction [Colforsin results in increased expression of STAR protein]]; Ryanodine inhibits the reaction [Colforsin results in increased expression of NR4A1 mRNA]; Ryanodine inhibits the reaction [Colforsin results in increased expression of NR4A1 protein]; W 7 inhibits the reaction [Colforsin results in increased expression of NR4A1 mRNA]; W 7 inhibits the reaction [Colforsin results in increased expression of NR4A1 protein]
NR4A1 protein inhibits the reaction [Colforsin results in increased expression of CYP19A1 mRNA]
CTD PMID:8164692 PMID:19822197 PMID:23183170 PMID:26783879 NCBI chr 7:132,368,399...132,389,300
Ensembl chr 7:132,374,840...132,389,297
JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 multiple interactions
increases expression
ISO 666-15 compound inhibits the reaction [Colforsin results in increased expression of NR4A2 mRNA]; NR4A2 protein inhibits the reaction [Colforsin results in increased expression of CYP19A1 mRNA]
Colforsin results in increased expression of NR4A2 mRNA; Colforsin results in increased expression of NR4A2 protein
CTD PMID:19732956 PMID:19822197 PMID:26023867 NCBI chr 3:41,689,847...41,707,036
Ensembl chr 3:41,689,851...41,697,877
JBrowse link
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 multiple interactions ISO NR4A3 protein inhibits the reaction [Colforsin results in increased expression of CYP19A1 mRNA] CTD PMID:19822197 NCBI chr 5:62,361,588...62,401,489
Ensembl chr 5:62,361,822...62,402,733
JBrowse link
G Nr5a1 nuclear receptor subfamily 5, group A, member 1 affects expression ISO Colforsin affects the expression of NR5A1 mRNA CTD PMID:20726872 NCBI chr 3:22,464,786...22,486,328
Ensembl chr 3:22,465,502...22,486,328
JBrowse link
G Nr5a2 nuclear receptor subfamily 5, group A, member 2 multiple interactions
increases expression
ISO alitretinoin inhibits the reaction [NR5A2 protein promotes the reaction [[Colforsin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CYP19A1 mRNA]]; NR5A2 protein promotes the reaction [[Colforsin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CYP19A1 mRNA]
Colforsin results in increased expression of NR5A2 mRNA
CTD PMID:16357189 NCBI chr13:48,313,634...48,433,494
Ensembl chr13:48,316,301...48,433,326
JBrowse link
G Nrg1 neuregulin 1 multiple interactions ISO [Colforsin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of NRG1 mRNA; U 0126 inhibits the reaction [[Colforsin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of NRG1 mRNA] CTD PMID:21047912 NCBI chr16:59,250,658...60,303,024
Ensembl chr16:59,250,854...60,296,884
JBrowse link
G Ntf3 neurotrophin 3 increases expression EXP Colforsin results in increased expression of NTF3 protein CTD PMID:19854260 NCBI chr 4:158,914,984...158,984,453
Ensembl chr 4:158,914,957...158,984,596
JBrowse link
G Numa1 nuclear mitotic apparatus protein 1 decreases expression ISO Colforsin results in decreased expression of NUMA1 mRNA CTD PMID:16751804 NCBI chr 1:156,297,907...156,372,855
Ensembl chr 1:156,326,259...156,372,855
JBrowse link
G Oxt oxytocin/neurophysin I prepropeptide multiple interactions ISO BMP6 protein inhibits the reaction [Colforsin results in increased expression of OXT mRNA] CTD PMID:18936084 NCBI chr 3:117,782,650...117,783,490
Ensembl chr 3:117,782,650...117,783,490
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions
increases cleavage
ISO [Colforsin co-treated with Theophylline] inhibits the reaction [Etoposide results in increased cleavage of PARP1 protein]
Colforsin results in increased cleavage of PARP1 protein
CTD PMID:9454737 PMID:31278978 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pax8 paired box 8 increases expression ISO Colforsin results in increased expression of PAX8 mRNA; Colforsin results in increased expression of PAX8 protein CTD PMID:15961562 NCBI chr 3:7,185,721...7,242,363
Ensembl chr 3:7,185,723...7,242,363
JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 increases expression
multiple interactions
EXP
ISO
Colforsin results in increased expression of PCK1 mRNA
Colforsin inhibits the reaction [Leflunomide results in increased expression of PCK1 mRNA]; Colforsin inhibits the reaction [teriflunomide results in increased expression of PCK1 mRNA]
Dexamethasone promotes the reaction [Colforsin results in increased expression of PCK1 mRNA]
CTD PMID:25851902 PMID:30364229 NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191
JBrowse link
G Pde1b phosphodiesterase 1B multiple interactions ISO PDE1B protein affects the reaction [Colforsin results in increased phosphorylation of PPP1R1B protein] CTD PMID:12077213 NCBI chr 7:134,627,378...134,654,581
Ensembl chr 7:134,627,322...134,654,580
JBrowse link
G Pde2a phosphodiesterase 2A multiple interactions ISO PDE2A protein inhibits the reaction [Colforsin affects the localization of AHR protein] CTD PMID:17329248 NCBI chr 1:155,823,590...155,915,434
Ensembl chr 1:155,813,180...155,915,434
JBrowse link
G Pde4b phosphodiesterase 4B increases expression ISO Colforsin results in increased expression of PDE4B mRNA CTD PMID:15967414 NCBI chr 5:116,799,827...117,367,707
Ensembl chr 5:116,799,971...117,367,696
JBrowse link
G Pde4d phosphodiesterase 4D increases expression ISO Colforsin results in increased expression of PDE4D mRNA CTD PMID:15967414 NCBI chr 2:40,014,933...41,529,190
Ensembl chr 2:40,019,933...41,525,884
JBrowse link
G Pdk1 pyruvate dehydrogenase kinase 1 affects response to substance
multiple interactions
ISO PDK1 protein affects the susceptibility to Colforsin
[PDK1 protein affects the susceptibility to Colforsin] which affects the abundance of Cyclic AMP; tubacin affects the reaction [[PDK1 protein affects the susceptibility to Colforsin] which affects the abundance of Cyclic AMP]
CTD PMID:28887310 NCBI chr 3:56,705,824...56,733,040
Ensembl chr 3:56,705,871...56,733,038
JBrowse link
G Per1 period circadian regulator 1 multiple interactions
increases expression
ISO [Colforsin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PER1 mRNA; AHR protein inhibits the reaction [[Colforsin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PER1 mRNA]; beta-Naphthoflavone inhibits the reaction [Colforsin results in increased expression of PER1 mRNA] CTD PMID:23291558 NCBI chr10:53,800,126...53,814,963
Ensembl chr10:53,805,535...53,814,431
JBrowse link
G Pgf placental growth factor increases expression
multiple interactions
ISO Colforsin results in increased expression of PGF mRNA
perfluorooctane sulfonic acid inhibits the reaction [Colforsin results in increased expression of PGF mRNA]
CTD PMID:33144174 NCBI chr 6:104,816,102...104,826,685
Ensembl chr 6:104,816,104...104,826,685
JBrowse link
G Pgr progesterone receptor increases expression ISO Colforsin results in increased expression of PGR mRNA CTD PMID:20378682 NCBI chr 8:6,073,216...6,131,552
Ensembl chr 8:6,072,673...6,131,344
JBrowse link
G Pias1 protein inhibitor of activated STAT, 1 decreases expression ISO Colforsin results in decreased expression of PIAS1 mRNA CTD PMID:16751804 NCBI chr 8:63,338,150...63,451,670
Ensembl chr 8:63,338,150...63,438,905
JBrowse link
G Pink1 PTEN induced kinase 1 multiple interactions ISO PINK1 protein affects the reaction [Colforsin results in decreased expression of DNM1L protein] CTD PMID:24792327 NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635
JBrowse link
G Pla2g2a phospholipase A2 group IIA multiple interactions ISO Colforsin inhibits the reaction [IFNG protein promotes the reaction [decitabine results in increased expression of PLA2G2A protein]] CTD PMID:18953428 NCBI chr 5:151,076,442...151,079,019
Ensembl chr 5:151,076,442...151,079,014
JBrowse link
G Pnpla2 patatin-like phospholipase domain containing 2 multiple interactions ISO PNPLA2 protein affects the reaction [Colforsin results in increased phosphorylation of and results in increased activity of PRKAA1 protein] CTD PMID:18390901 NCBI chr 1:196,552,723...196,557,805
Ensembl chr 1:196,552,723...196,557,805
JBrowse link
G Pnpla6 patatin-like phospholipase domain containing 6 multiple interactions
increases expression
ISO 1-Methyl-3-isobutylxanthine promotes the reaction [Colforsin results in increased expression of and results in increased activity of PNPLA6 protein]; [Colforsin co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of PNPLA6 mRNA; Colforsin results in increased expression of and results in increased activity of PNPLA6 protein; Cycloheximide inhibits the reaction [[Colforsin co-treated with 1-Methyl-3-isobutylxanthine] results in increased activity of PNPLA6 protein]; Cycloheximide inhibits the reaction [Colforsin results in increased activity of PNPLA6 protein]
Colforsin results in increased expression of PNPLA6 mRNA
CTD PMID:20380879 NCBI chr12:1,574,387...1,603,735
Ensembl chr12:1,560,363...1,603,734
JBrowse link
G Pou1f1 POU class 1 homeobox 1 multiple interactions EXP Colforsin promotes the reaction [CREB1 protein binds to POU1F1 promoter]; resveratrol inhibits the reaction [Colforsin promotes the reaction [CREB1 protein binds to POU1F1 promoter]] CTD PMID:23292070 NCBI chr11:3,316,818...3,334,804
Ensembl chr11:3,317,058...3,334,801
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma decreases expression ISO Colforsin results in decreased expression of PPARG mRNA CTD PMID:31278978 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha increases expression ISO Colforsin results in increased expression of PPARGC1A mRNA CTD PMID:16357189 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
JBrowse link
G Ppargc1b PPARG coactivator 1 beta increases expression ISO Colforsin results in increased expression of PPARGC1B mRNA CTD PMID:16357189 NCBI chr18:54,758,891...54,861,103
Ensembl chr18:54,758,902...54,861,194
JBrowse link
G Ppp1r12a protein phosphatase 1, regulatory subunit 12A increases phosphorylation
multiple interactions
ISO Colforsin results in increased phosphorylation of PPP1R12A protein
Capsaicin inhibits the reaction [Colforsin results in increased phosphorylation of PPP1R12A protein]; capsazepine inhibits the reaction [Colforsin results in increased phosphorylation of PPP1R12A protein]
CTD PMID:21474433 NCBI chr 7:43,482,808...43,593,689
Ensembl chr 7:43,482,803...43,593,425
JBrowse link
G Ppp1r1b protein phosphatase 1, regulatory (inhibitor) subunit 1B increases phosphorylation
multiple interactions
ISO Colforsin results in increased phosphorylation of PPP1R1B protein
PDE1B protein affects the reaction [Colforsin results in increased phosphorylation of PPP1R1B protein]
CTD PMID:12077213 NCBI chr10:83,347,731...83,356,775
Ensembl chr10:83,347,731...83,356,775
JBrowse link
G Prima1 proline rich membrane anchor 1 increases expression EXP Colforsin results in increased expression of PRIMA1 mRNA CTD PMID:18514641 NCBI chr 6:122,338,365...122,390,955
Ensembl chr 6:122,338,370...122,389,921
JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 multiple interactions ISO Colforsin results in increased phosphorylation of and results in increased activity of PRKAA1 protein; PNPLA2 protein affects the reaction [Colforsin results in increased phosphorylation of and results in increased activity of PRKAA1 protein] CTD PMID:18390901 NCBI chr 2:54,240,298...54,275,978
Ensembl chr 2:54,240,137...54,275,978
JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha multiple interactions
increases activity
EXP
ISO
Colforsin inhibits the reaction [Oxidopamine results in decreased phosphorylation of PRKACA protein]
Colforsin results in increased activity of PRKACA protein
CTD PMID:16339297 PMID:28601556 NCBI chr19:24,155,081...24,178,430
Ensembl chr19:24,155,090...24,178,430
JBrowse link
G Prkacb protein kinase cAMP-activated catalytic subunit beta multiple interactions ISO [PRKACB protein mutant form results in increased susceptibility to [Colforsin co-treated with 1-Methyl-3-isobutylxanthine]] results in decreased stability of [PRKACB protein mutant form binds to PRKAR1A protein]; [PRKACB protein mutant form results in increased susceptibility to [Colforsin co-treated with 1-Methyl-3-isobutylxanthine]] results in decreased stability of [PRKACB protein mutant form binds to PRKAR1B protein]; PRKACB protein mutant form results in increased susceptibility to [Colforsin co-treated with 1-Methyl-3-isobutylxanthine] CTD PMID:29669941 NCBI chr 2:235,636,878...235,726,928
Ensembl chr 2:235,636,885...235,726,198
JBrowse link
G Prkar1a protein kinase cAMP-dependent type I regulatory subunit alpha multiple interactions ISO [PRKACB protein mutant form results in increased susceptibility to [Colforsin co-treated with 1-Methyl-3-isobutylxanthine]] results in decreased stability of [PRKACB protein mutant form binds to PRKAR1A protein] CTD PMID:29669941 NCBI chr10:94,621,042...94,639,534
Ensembl chr10:94,620,039...94,639,041
JBrowse link
G Prkar1b protein kinase cAMP-dependent type I regulatory subunit beta multiple interactions ISO [PRKACB protein mutant form results in increased susceptibility to [Colforsin co-treated with 1-Methyl-3-isobutylxanthine]] results in decreased stability of [PRKACB protein mutant form binds to PRKAR1B protein] CTD PMID:29669941 NCBI chr12:15,492,233...15,624,942
Ensembl chr12:15,511,801...15,624,942
JBrowse link
G Prkar2a protein kinase cAMP-dependent type II regulatory subunit alpha increases phosphorylation ISO Colforsin results in increased phosphorylation of PRKAR2A protein CTD PMID:25943029 NCBI chr 8:109,393,189...109,458,832
Ensembl chr 8:109,395,833...109,455,628
JBrowse link
G Prl prolactin multiple interactions
increases expression
EXP
ISO
Colforsin inhibits the reaction [Octreotide results in decreased secretion of PRL protein]; Octreotide inhibits the reaction [Colforsin results in increased expression of PRL protein]
[Medroxyprogesterone Acetate co-treated with Estradiol co-treated with Colforsin] results in increased expression of PRL mRNA; [Medroxyprogesterone Acetate co-treated with Estradiol co-treated with Colforsin] results in increased secretion of PRL protein; Cannabidiol inhibits the reaction [[Medroxyprogesterone Acetate co-treated with Estradiol co-treated with Colforsin] results in increased expression of PRL mRNA]; Cannabidiol inhibits the reaction [[Medroxyprogesterone Acetate co-treated with Estradiol co-treated with Colforsin] results in increased secretion of PRL protein]; Cannabinol inhibits the reaction [[Medroxyprogesterone Acetate co-treated with Estradiol co-treated with Colforsin] results in increased expression of PRL mRNA]; Cannabinol inhibits the reaction [[Medroxyprogesterone Acetate co-treated with Estradiol co-treated with Colforsin] results in increased secretion of PRL protein]; Dronabinol inhibits the reaction [[Medroxyprogesterone Acetate co-treated with Estradiol co-treated with Colforsin] results in increased expression of PRL mRNA]; Dronabinol inhibits the reaction [[Medroxyprogesterone Acetate co-treated with Estradiol co-treated with Colforsin] results in increased secretion of PRL protein]; Rimonabant inhibits the reaction [Dronabinol inhibits the reaction [[Medroxyprogesterone Acetate co-treated with Estradiol co-treated with Colforsin] results in increased expression of PRL mRNA]]
CTD PMID:1322274 PMID:31154070 NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062
JBrowse link
G Ptch1 patched 1 multiple interactions EXP Colforsin inhibits the reaction [Carbon Tetrachloride results in increased expression of PTCH1 mRNA] CTD PMID:27590029 NCBI chr17:1,542,705...1,607,730
Ensembl chr17:1,542,877...1,607,333
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases expression
ISO
EXP
Colforsin promotes the reaction [bisperoxovanadium results in increased expression of PTGS2 mRNA]; Colforsin promotes the reaction [IL1B protein results in increased expression of PTGS2 protein]
Colforsin results in increased expression of PTGS2 mRNA
bifenthrin inhibits the reaction [Colforsin results in increased expression of PTGS2 mRNA]; Colforsin inhibits the reaction [Carbon Tetrachloride results in increased expression of PTGS2 protein]
Colforsin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA]; Colforsin promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA]
CTD PMID:11112151 PMID:12493747 PMID:15213229 PMID:17407152 PMID:19063610 More... NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Rap1a RAP1A, member of RAS oncogene family increases activity
multiple interactions
EXP Colforsin results in increased activity of RAP1A protein
Rolipram affects the reaction [Colforsin results in increased activity of RAP1A protein]
CTD PMID:10908723 NCBI chr 2:193,208,631...193,286,513
Ensembl chr 2:193,208,635...193,286,501
JBrowse link
G Rap1b RAP1B, member of RAS oncogene family multiple interactions
increases activity
EXP Rolipram affects the reaction [Colforsin results in increased activity of RAP1B protein] CTD PMID:10908723 NCBI chr 7:53,423,039...53,456,388
Ensembl chr 7:53,423,130...53,456,370
JBrowse link
G Rarres2 retinoic acid receptor responder 2 multiple interactions EXP RARRES2 protein inhibits the reaction [Colforsin results in increased expression of CYP11A1 protein]; RARRES2 protein inhibits the reaction [Colforsin results in increased expression of CYP19A1 protein] CTD PMID:22948218 NCBI chr 4:77,522,549...77,525,733
Ensembl chr 4:77,522,535...77,525,556
JBrowse link
G Rb1 RB transcriptional corepressor 1 multiple interactions ISO [Colforsin co-treated with Theophylline] inhibits the reaction [Etoposide results in decreased phosphorylation of RB1 protein] CTD PMID:9454737 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions EXP
ISO
Colforsin inhibits the reaction [Carbon Tetrachloride results in increased expression of RELA protein]; Colforsin inhibits the reaction [Morphine results in increased phosphorylation of RELA protein]
RELA affects the reaction [[monobutyl phthalate co-treated with Colforsin] results in increased secretion of Progesterone]
CTD PMID:22258905 PMID:26745512 PMID:27590029 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Relb RELB proto-oncogene, NF-kB subunit multiple interactions ISO Colforsin promotes the reaction [[AHR protein binds to RELB protein] which binds to CXCL8 promoter]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Colforsin promotes the reaction [[AHR protein binds to RELB protein] which binds to CXCL8 promoter]] CTD PMID:17823304 NCBI chr 1:79,257,738...79,285,490
Ensembl chr 1:79,257,725...79,285,507
JBrowse link
G Ren renin increases expression
multiple interactions
increases secretion
ISO Colforsin results in increased expression of REN mRNA
[Sodium, Dietary deficiency results in increased susceptibility to Colforsin] which results in increased secretion of REN protein
Colforsin results in increased secretion of REN protein
CTD PMID:9256163 PMID:10432392 NCBI chr13:44,796,260...44,807,491
Ensembl chr13:44,796,091...44,807,489
JBrowse link
G Rnf4 ring finger protein 4 multiple interactions EXP [Tetradecanoylphorbol Acetate co-treated with Colforsin] results in increased expression of RNF4 mRNA CTD PMID:14749358 NCBI chr14:76,401,292...76,423,270
Ensembl chr14:76,401,299...76,422,566
JBrowse link
G Rrp12 ribosomal RNA processing 12 homolog increases expression ISO Colforsin results in increased expression of RRP12 mRNA CTD PMID:16751804 NCBI chr 1:240,672,378...240,706,499
Ensembl chr 1:240,672,382...240,706,018
JBrowse link
G Runx1 RUNX family transcription factor 1 affects splicing
multiple interactions
EXP Colforsin affects the splicing of RUNX1 exon
HNRNPA1 mutant form inhibits the reaction [Colforsin affects the splicing of RUNX1 exon]
CTD PMID:22684629 NCBI chr11:31,839,880...32,074,427
Ensembl chr11:31,843,764...32,074,542
JBrowse link
G Runx2 RUNX family transcription factor 2 increases expression EXP Colforsin results in increased expression of RUNX2 mRNA CTD PMID:20197312 NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167
JBrowse link
G Sele selectin E multiple interactions ISO [Colforsin co-treated with Rolipram] inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of SELE protein]; [Colforsin co-treated with Rolipram] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SELE protein]; [Colforsin co-treated with Rolipram] inhibits the reaction [TNF protein results in increased expression of SELE protein]; [Colforsin co-treated with Rolipram] inhibits the reaction [TNF protein results in increased secretion of SELE protein] CTD PMID:8780174 NCBI chr13:76,402,841...76,412,741
Ensembl chr13:76,403,304...76,412,741
JBrowse link
G Selenop selenoprotein P multiple interactions EXP Colforsin promotes the reaction [Dexamethasone results in increased expression of SELENOP mRNA] CTD PMID:18972406 NCBI chr 2:52,498,123...52,508,409
Ensembl chr 2:52,498,339...52,508,852
JBrowse link
G Sesn1 sestrin 1 decreases expression
multiple interactions
ISO Colforsin results in decreased expression of SESN1 mRNA; Colforsin results in decreased expression of SESN1 protein
AR protein affects the reaction [Colforsin results in decreased expression of SESN1 protein]
CTD PMID:16751804 NCBI chr20:45,294,876...45,387,698
Ensembl chr20:45,294,871...45,387,697
JBrowse link
G Sftpc surfactant protein C increases expression ISO Colforsin results in increased expression of SFTPC mRNA CTD PMID:2539393 NCBI chr15:45,596,565...45,599,615
Ensembl chr15:45,596,574...45,610,777
JBrowse link
G Sirt1 sirtuin 1 multiple interactions EXP
ISO
SIRT1 mutant form inhibits the reaction [Resveratrol inhibits the reaction [Colforsin results in increased phosphorylation of CREB1 protein]]; SIRT1 protein inhibits the reaction [Colforsin results in increased phosphorylation of CREB1 protein]; SIRT1 protein mutant form inhibits the reaction [Colforsin results in increased phosphorylation of CREB1 protein]
Colforsin inhibits the reaction [Caffeine results in decreased expression of SIRT1 mRNA]
CTD PMID:23292070 PMID:30825513 NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Slc26a4 solute carrier family 26 member 4 increases expression ISO Colforsin results in increased expression of SLC26A4 protein CTD PMID:22811483 NCBI chr 6:48,107,575...48,153,762
Ensembl chr 6:48,107,588...48,145,703
JBrowse link
G Slc2a4 solute carrier family 2 member 4 multiple interactions ISO Colforsin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of SLC2A4 mRNA] CTD PMID:17407152 NCBI chr10:54,666,015...54,671,581
Ensembl chr10:54,666,015...54,671,565
JBrowse link
G Slc2a5 solute carrier family 2 member 5 multiple interactions
increases expression
ISO
EXP
Colforsin promotes the reaction [Fructose results in increased expression of SLC2A5 mRNA]; Colforsin promotes the reaction [Glucose results in increased expression of SLC2A5 mRNA]
[[Colforsin results in increased abundance of Cyclic AMP] which results in increased expression of SLC2A5 protein] which results in increased uptake of Fructose; [Colforsin results in increased abundance of Cyclic AMP] which results in increased expression of SLC2A5 protein; Colforsin results in increased expression of and results in decreased degradation of SLC2A5 mRNA
Colforsin results in increased expression of SLC2A5 mRNA
CTD PMID:8037665 PMID:12820898 NCBI chr 5:160,583,055...160,609,994
Ensembl chr 5:160,583,234...160,611,106
JBrowse link
G Slc30a1 solute carrier family 30 member 1 increases expression ISO Colforsin results in increased expression of SLC30A1 mRNA CTD PMID:16503475 NCBI chr13:103,491,037...103,494,910
Ensembl chr13:103,491,037...103,494,910
JBrowse link
G Slc30a2 solute carrier family 30 member 2 increases expression ISO Colforsin results in increased expression of SLC30A2 mRNA CTD PMID:16503475 NCBI chr 5:146,559,733...146,571,957
Ensembl chr 5:146,559,733...146,571,956
JBrowse link
G Slc30a4 solute carrier family 30 member 4 increases expression ISO Colforsin results in increased expression of SLC30A4 mRNA CTD PMID:16503475 NCBI chr 3:109,753,270...109,775,306
Ensembl chr 3:109,753,273...109,775,306
JBrowse link
G Slc30a7 solute carrier family 30 member 7 decreases expression ISO Colforsin results in decreased expression of SLC30A7 mRNA CTD PMID:16751804 NCBI chr 2:203,855,484...203,922,155
Ensembl chr 2:203,859,175...203,922,132
JBrowse link
G Slc45a2 solute carrier family 45, member 2 increases expression ISO Colforsin results in increased expression of SLC45A2 mRNA CTD PMID:17460731 NCBI chr 2:59,963,599...59,996,408
Ensembl chr 2:59,963,706...59,996,317
JBrowse link
G Slc5a5 solute carrier family 5 member 5 multiple interactions
increases expression
ISO
EXP
Colforsin inhibits the reaction [[Tretinoin co-treated with Hydrocortisone] results in increased activity of SLC5A5 protein]
Colforsin results in increased expression of SLC5A5 mRNA; Colforsin results in increased expression of SLC5A5 protein
CTD PMID:16439463 PMID:16954431 NCBI chr16:18,546,709...18,556,698
Ensembl chr16:18,546,709...18,556,697
JBrowse link
G Smo smoothened, frizzled class receptor multiple interactions EXP Colforsin inhibits the reaction [Carbon Tetrachloride results in increased expression of SMO mRNA] CTD PMID:27590029 NCBI chr 4:58,344,101...58,372,828
Ensembl chr 4:58,343,529...58,373,829
JBrowse link
G Snai1 snail family transcriptional repressor 1 decreases expression ISO Colforsin results in decreased expression of SNAI1 mRNA CTD PMID:30983542 NCBI chr 3:156,248,479...156,252,969
Ensembl chr 3:156,248,485...156,252,969
JBrowse link
G Snai2 snail family transcriptional repressor 2 decreases expression ISO Colforsin results in decreased expression of SNAI2 mRNA CTD PMID:30983542 NCBI chr11:86,183,800...86,186,109
Ensembl chr11:86,181,909...86,186,200
JBrowse link
G Snap25 synaptosome associated protein 25 affects splicing
multiple interactions
EXP Colforsin affects the splicing of SNAP25 exon
Colforsin promotes the reaction [HNRNPK protein binds to SNAP25 exon]; HNRNPA1 mutant form inhibits the reaction [Colforsin affects the splicing of SNAP25 exon]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Colforsin affects the splicing of SNAP25 exon]
CTD PMID:22684629 NCBI chr 3:124,041,898...124,123,761
Ensembl chr 3:124,041,898...124,123,760
JBrowse link
G Socs3 suppressor of cytokine signaling 3 multiple interactions
increases expression
ISO Colforsin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of SOCS3 mRNA]
Colforsin results in increased expression of SOCS3 protein
2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide inhibits the reaction [[[Colforsin co-treated with Rolipram] results in increased abundance of Cyclic AMP] which results in increased expression of SOCS3 protein]; [[Colforsin co-treated with Rolipram] results in increased abundance of Cyclic AMP] which results in increased expression of SOCS3 protein; dorsomorphin inhibits the reaction [[[Colforsin co-treated with Rolipram] results in increased abundance of Cyclic AMP] which results in increased expression of SOCS3 protein]
CTD PMID:17407152 PMID:23782265 NCBI chr10:103,193,909...103,197,322
Ensembl chr10:103,193,537...103,197,787
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions ISO [EGF co-treated with Colforsin co-treated with Rotenone] results in increased expression of SOD1 mRNA; [EGF co-treated with Colforsin co-treated with Rotenone] results in increased expression of SOD1 protein; Acetylcysteine inhibits the reaction [[EGF co-treated with Colforsin co-treated with Rotenone] results in increased expression of SOD1 mRNA]; Acetylcysteine inhibits the reaction [[EGF co-treated with Colforsin co-treated with Rotenone] results in increased expression of SOD1 protein] CTD PMID:32092105 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Sod2 superoxide dismutase 2 increases expression
multiple interactions
increases activity
ISO Colforsin results in increased expression of SOD2 mRNA
[EGF co-treated with Colforsin co-treated with Rotenone] results in increased expression of SOD2 mRNA; [EGF co-treated with Colforsin co-treated with Rotenone] results in increased expression of SOD2 protein; Acetylcysteine inhibits the reaction [[EGF co-treated with Colforsin co-treated with Rotenone] results in increased expression of SOD2 mRNA]; Acetylcysteine inhibits the reaction [[EGF co-treated with Colforsin co-treated with Rotenone] results in increased expression of SOD2 protein]
Colforsin results in increased activity of SOD2 protein
CTD PMID:12093828 PMID:32092105 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Spcs3 signal peptidase complex subunit 3 increases expression ISO Colforsin results in increased expression of SPCS3 mRNA CTD PMID:16751804 NCBI chr16:37,305,358...37,310,792
Ensembl chr16:37,305,305...37,331,746
JBrowse link
G Sqstm1 sequestosome 1 increases degradation ISO Colforsin results in increased degradation of SQSTM1 protein CTD PMID:25943029 NCBI chr10:34,525,517...34,536,685
Ensembl chr10:34,525,519...34,536,673
JBrowse link
G Srd5a1 steroid 5 alpha-reductase 1 increases expression ISO Colforsin results in increased expression of SRD5A1 mRNA CTD PMID:22461451 NCBI chr 1:33,686,069...33,720,468
Ensembl chr 1:33,686,391...33,720,461
JBrowse link
G Srebf2 sterol regulatory element binding transcription factor 2 multiple interactions ISO Colforsin inhibits the reaction [Caffeine results in increased expression of SREBF2 mRNA] CTD PMID:30825513 NCBI chr 7:113,663,202...113,720,850
Ensembl chr 7:113,663,202...113,720,848
JBrowse link
G Sst somatostatin multiple interactions ISO [SST protein co-treated with SSTR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP] CTD PMID:22056254 NCBI chr11:76,956,896...76,958,173
Ensembl chr11:76,956,896...76,958,173
JBrowse link
G Sstr2 somatostatin receptor 2 multiple interactions ISO [64Cu-CB-TE2A-Y3-TATE co-treated with SSTR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]; [SST protein co-treated with SSTR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP] CTD PMID:22056254 NCBI chr10:98,664,204...98,671,370
Ensembl chr10:98,664,216...98,674,351
JBrowse link
G Star steroidogenic acute regulatory protein multiple interactions
increases expression
ISO
EXP
BMP6 protein inhibits the reaction [Colforsin results in increased expression of STAR mRNA]; Hexachlorocyclohexane inhibits the reaction [Colforsin results in increased expression of STAR mRNA]; Valproic Acid inhibits the reaction [Colforsin results in increased expression of STAR mRNA]
[Colforsin co-treated with deoxynivalenol] results in increased expression of STAR mRNA; Colforsin affects the reaction [Zearalenone results in increased expression of STAR mRNA]; NR4A1 protein inhibits the reaction [Ryanodine inhibits the reaction [Colforsin results in increased expression of STAR protein]]; Ryanodine inhibits the reaction [Colforsin results in increased expression of STAR mRNA]; Ryanodine inhibits the reaction [Colforsin results in increased expression of STAR protein]; W 7 inhibits the reaction [Colforsin results in increased expression of STAR mRNA]; W 7 inhibits the reaction [Colforsin results in increased expression of STAR protein]
Colforsin results in increased expression of STAR mRNA; Colforsin results in increased expression of STAR protein
[Atrazine co-treated with Colforsin] results in increased expression of STAR mRNA
CTD PMID:14691014 PMID:15967414 PMID:16254025 PMID:16935330 PMID:17080404 More... NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672
JBrowse link
G Sult1e1 sulfotransferase family 1E member 1 decreases expression ISO Colforsin results in decreased expression of SULT1E1 mRNA CTD PMID:22446829 NCBI chr14:20,422,324...20,439,562
Ensembl chr14:20,422,324...20,439,275
JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 decreases expression
multiple interactions
ISO Colforsin results in decreased expression of SULT2A1 mRNA
Hexachlorocyclohexane promotes the reaction [Colforsin results in decreased expression of SULT2A1 mRNA]
CTD PMID:17080404 PMID:22446829 NCBI chr 1:75,451,178...75,508,142 JBrowse link
G Sult2b1 sulfotransferase family 2B member 1 decreases expression ISO Colforsin results in decreased expression of SULT2B1 mRNA CTD PMID:22446829 NCBI chr 1:96,200,155...96,261,295
Ensembl chr 1:96,200,156...96,261,295
JBrowse link
G Tac1 tachykinin, precursor 1 multiple interactions EXP Colforsin promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]; HU 211 inhibits the reaction [Colforsin promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]] CTD PMID:15750287 NCBI chr 4:35,679,183...35,687,180
Ensembl chr 4:35,679,704...35,687,178
JBrowse link
G Tbr1 T-box brain transcription factor 1 multiple interactions EXP Colforsin promotes the reaction [CASK protein modified form binds to TBR1 protein] CTD PMID:20067577 NCBI chr 3:46,350,237...46,368,397
Ensembl chr 3:46,351,213...46,361,041
JBrowse link
G Testin testin gene affects expression EXP Colforsin affects the expression of TESTIN mRNA CTD PMID:11090432 NCBI chr17:3,824,222...3,859,385
Ensembl chr17:3,846,899...3,859,385
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO