CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: acamprosate
Accession: CHEBI:51041
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Definition: An organosulfonic acid that is propane-1-sulfonic acid substituted by an acetylamino group at position 3.
Synonyms: exact_synonym: 3-acetamidopropane-1-sulfonic acid
related_synonym: 3-Acetamido-1-propanesulfonic acid; Formula=C5H11NO4S; InChI=1S/C5H11NO4S/c1-5(7)6-3-2-4-11(8,9)10/h2-4H2,1H3,(H,6,7)(H,8,9,10); InChIKey=AFCGFAGUEYAMAO-UHFFFAOYSA-N; N-Acetylhomotaurine; SMILES=CC(=O)NCCCS(O)(=O)=O; acamprosato; acamprosatum
xref: CAS:77337-76-9; DrugBank:DB00659; Drug_Central:38; KEGG:D07058
xref_mesh: MESH:C043877
xref: Reaxys:9618349; Wikipedia:Acamprosate
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DRD2
dopamine receptor D2
affects response to substance
EXP
DRD2 affects the susceptibility to acamprosate
CTD
PMID:19523047
NCBI chr11:113,409,605...113,475,398
Ensembl chr11:113,409,605...113,475,691
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FMR1
fragile X messenger ribonucleoprotein 1
multiple interactions
ISO
acamprosate inhibits the reaction [FMR1 protein affects the phosphorylation of MAPK1 protein]; acamprosate inhibits the reaction [FMR1 protein affects the phosphorylation of MAPK3 protein]
CTD
PMID:28616095
NCBI chr X:147,911,919...147,951,125
Ensembl chr X:147,911,919...147,951,125
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GABRA6
gamma-aminobutyric acid type A receptor subunit alpha6
affects response to substance
EXP
GABRA6 affects the susceptibility to acamprosate
CTD
PMID:19523047
NCBI chr 5:161,685,721...161,702,592
Ensembl chr 5:161,547,063...161,702,593
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GABRB2
gamma-aminobutyric acid type A receptor subunit beta2
affects response to substance
EXP
GABRB2 affects the susceptibility to acamprosate
CTD
PMID:19523047
NCBI chr 5:161,288,436...161,548,404
Ensembl chr 5:161,288,429...161,549,044
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GRM5
glutamate metabotropic receptor 5
affects response to substance
ISO
GRM5 affects the susceptibility to acamprosate
CTD
PMID:18377703
NCBI chr11:88,504,642...89,065,982
Ensembl chr11:88,504,576...89,065,982
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MAPK1
mitogen-activated protein kinase 1
multiple interactions
ISO
acamprosate inhibits the reaction [FMR1 protein affects the phosphorylation of MAPK1 protein]
CTD
PMID:28616095
NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680
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MAPK3
mitogen-activated protein kinase 3
multiple interactions
ISO
acamprosate inhibits the reaction [FMR1 protein affects the phosphorylation of MAPK3 protein]
CTD
PMID:28616095
NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506
G
PER2
period circadian regulator 2
affects response to substance
ISO
PER2 affects the susceptibility to acamprosate
CTD
PMID:21697518
NCBI chr 2:238,244,044...238,300,065
Ensembl chr 2:238,244,044...238,290,102
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