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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:dopamine uptake inhibitor
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Accession:CHEBI:51039 term browser browse the term
Definition:A dopaminergic agent that blocks the transport of dopamine into axon terminals or into storage vesicles within terminals. Most of the adrenergic uptake inhibitors also inhibit dopamine uptake.
Synonyms:related_synonym: DARI;   DRI;   dopamine reuptake inhibitor;   dopamine reuptake inhibitors;   dopamine uptake inhibitors
 xref: Wikipedia:Dopamine_uptake_inhibitor


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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19816
    role 19764
      biological role 19764
        pharmacological role 18825
          neurotransmitter agent 16439
            dopaminergic agent 5082
              dopamine uptake inhibitor 4555
                (S)-amphetamine + 3478
                1-[1-(1-benzothiophen-2-yl)cyclohexyl]piperidine 0
                1-[1-(1-benzothiophen-2-yl)cyclohexyl]piperidine maleate 0
                1-[2-(benzhydryloxy)ethyl]-4-(3-phenylpropyl)piperazine 2
                1-[2-(benzhydryloxy)ethyl]-4-(3-phenylpropyl)piperazine dihydrochloride 0
                amineptine + 0
                amphetamine + 2209
                benzphetamine + 1
                benzphetamine hydrochloride 0
                cocaine 1434
                cyclo(L-His-L-Pro) 0
                methylphenidate 128
                minaprine + 0
                nefopam 1
                nefopam hydrochloride 0
                nomifensine + 5
                vanoxerine 0
                vanoxerine dihydrochloride 10
                venlafaxine + 176
Path 2
Term Annotations click to browse term
  CHEBI ontology 19816
    role 19764
      application 19426
        pharmaceutical 19301
          drug 19301
            neurotransmitter agent 16439
              dopaminergic agent 5082
                dopamine uptake inhibitor 4555
                  (S)-amphetamine + 3478
                  1-[1-(1-benzothiophen-2-yl)cyclohexyl]piperidine 0
                  1-[1-(1-benzothiophen-2-yl)cyclohexyl]piperidine maleate 0
                  1-[2-(benzhydryloxy)ethyl]-4-(3-phenylpropyl)piperazine 2
                  1-[2-(benzhydryloxy)ethyl]-4-(3-phenylpropyl)piperazine dihydrochloride 0
                  amineptine + 0
                  amphetamine + 2209
                  benzphetamine + 1
                  benzphetamine hydrochloride 0
                  cocaine 1434
                  cyclo(L-His-L-Pro) 0
                  methylphenidate 128
                  minaprine + 0
                  nefopam 1
                  nefopam hydrochloride 0
                  nomifensine + 5
                  vanoxerine 0
                  vanoxerine dihydrochloride 10
                  venlafaxine + 176
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.