Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:metixene
go back to main search page
Accession:CHEBI:51024 term browser browse the term
Definition:A thioxanthene that has formula C20H23NS.
Synonyms:exact_synonym: 1-methyl-3-(9H-thioxanthen-9-ylmethyl)piperidine
 related_synonym: Formula=C20H23NS;   InChI=1S/C20H23NS/c1-21-12-6-7-15(14-21)13-18-16-8-2-4-10-19(16)22-20-11-5-3-9-17(18)20/h2-5,8-11,15,18H,6-7,12-14H2,1H3;   InChIKey=MJFJKKXQDNNUJF-UHFFFAOYSA-N;   Methixen;   Metisene;   SMILES=CN1CCCC(CC2c3ccccc3Sc3ccccc23)C1;   metixeno;   metixenum
 xref: Beilstein:267181;   CAS:4969-02-2;   DrugBank:DB00340;   Drug_Central:1780;   LINCS:LSM-1467
 xref_mesh: MESH:C005111
 xref: Wikipedia:Metixene


show annotations for term's descendants           Sort by:
 
metixene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO methixene results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19786
    role 19732
      biological role 19732
        pharmacological role 18842
          antagonist 16280
            histamine antagonist 4619
              metixene 1
                methixene hydrochloride 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19786
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19675
                    p-block element atom 19675
                      carbon group element atom 19596
                        carbon atom 19586
                          organic molecular entity 19586
                            organic molecule 19519
                              organic cyclic compound 19349
                                organic heterocyclic compound 18574
                                  organic heteropolycyclic compound 18065
                                    organic heterotricyclic compound 14615
                                      thioxanthenes 202
                                        metixene 1
                                          methixene hydrochloride 0
paths to the root