|
G |
CYP2C49 |
cytochrome P450 2C49 |
decreases response to substance |
EXP |
CYP2C49 protein results in decreased susceptibility to alachlor |
CTD |
PMID:16315095 |
|
NCBI chr14:106,571,803...106,612,082
Ensembl chr14:106,285,173...106,612,455
|
|
|
G |
FMO1 |
flavin containing dimethylaniline monoxygenase 1 |
increases metabolic processing |
EXP |
FMO1 protein results in increased metabolism of Cysteamine |
CTD |
PMID:6439199 |
|
NCBI chr 9:63,860,957...63,895,086
Ensembl chr 9:63,868,064...63,895,076
|
|
|
G |
AGER |
advanced glycosylation end-product specific receptor |
increases expression |
EXP |
fumonisin B1 results in increased expression of AGER mRNA |
CTD |
PMID:32198028 |
|
NCBI chr 7:24,218,116...24,221,162
Ensembl chr 7:24,218,120...24,221,162
|
|
G |
APAF1 |
apoptotic peptidase activating factor 1 |
multiple interactions increases expression |
EXP |
fumonisin B1 promotes the reaction [ochratoxin A results in increased expression of APAF1 mRNA]; fumonisin B1 promotes the reaction [ochratoxin A results in increased expression of APAF1 protein] fumonisin B1 results in increased expression of APAF1 mRNA; fumonisin B1 results in increased expression of APAF1 protein |
CTD |
PMID:36397609 |
|
NCBI chr 5:85,166,616...85,258,751
Ensembl chr 5:85,166,628...85,258,364
|
|
G |
BAX |
BCL2 associated X, apoptosis regulator |
multiple interactions increases expression |
EXP |
[fumonisin B1 co-treated with ochratoxin A] results in increased expression of BAX mRNA; [fumonisin B1 co-treated with ochratoxin A] results in increased expression of BAX protein; Acetylcysteine inhibits the reaction [[fumonisin B1 co-treated with ochratoxin A] results in increased expression of BAX mRNA]; Acetylcysteine inhibits the reaction [[fumonisin B1 co-treated with ochratoxin A] results in increased expression of BAX protein]; fumonisin B1 promotes the reaction [ochratoxin A results in increased expression of BAX mRNA]; fumonisin B1 promotes the reaction [ochratoxin A results in increased expression of BAX protein]; ochratoxin A promotes the reaction [fumonisin B1 results in increased expression of BAX mRNA]; ochratoxin A promotes the reaction [fumonisin B1 results in increased expression of BAX protein]; pyrazolanthrone inhibits the reaction [[fumonisin B1 co-treated with ochratoxin A] results in increased expression of BAX mRNA] fumonisin B1 results in increased expression of BAX mRNA; fumonisin B1 results in increased expression of BAX protein |
CTD |
PMID:33905761 PMID:36397609 |
|
NCBI chr 6:54,222,341...54,228,150
Ensembl chr 6:54,222,336...54,228,140
|
|
G |
BCL2 |
BCL2 apoptosis regulator |
decreases expression multiple interactions |
EXP |
fumonisin B1 results in decreased expression of BCL2 mRNA; fumonisin B1 results in decreased expression of BCL2 protein [Acetylcysteine co-treated with fumonisin B1 co-treated with deoxynivalenol] results in increased expression of BCL2 protein; [Acetylcysteine co-treated with fumonisin B1] results in increased expression of BCL2 protein; [Acetylcysteine co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of BCL2 protein; [fumonisin B1 co-treated with deoxynivalenol] results in decreased expression of BCL2 mRNA; [fumonisin B1 co-treated with ochratoxin A] results in decreased expression of BCL2 mRNA; [fumonisin B1 co-treated with ochratoxin A] results in decreased expression of BCL2 protein; [fumonisin B1 co-treated with Zearalenone co-treated with deoxynivalenol] results in decreased expression of BCL2 protein; [fumonisin B1 co-treated with Zearalenone] results in decreased expression of BCL2 mRNA; Acetylcysteine inhibits the reaction [[fumonisin B1 co-treated with deoxynivalenol] results in decreased expression of BCL2 mRNA]; Acetylcysteine inhibits the reaction [[fumonisin B1 co-treated with ochratoxin A] results in decreased expression of BCL2 mRNA]; Acetylcysteine inhibits the reaction [[fumonisin B1 co-treated with ochratoxin A] results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [[fumonisin B1 co-treated with Zearalenone] results in decreased expression of BCL2 mRNA]; Acetylcysteine inhibits the reaction [fumonisin B1 promotes the reaction [Zearalenone results in decreased expression of BCL2 mRNA]]; fumonisin B1 inhibits the reaction [deoxynivalenol results in decreased expression of BCL2 protein]; fumonisin B1 inhibits the reaction [Zearalenone inhibits the reaction [deoxynivalenol results in decreased expression of BCL2 mRNA]]; fumonisin B1 promotes the reaction [ochratoxin A results in decreased expression of BCL2 mRNA]; fumonisin B1 promotes the reaction [ochratoxin A results in decreased expression of BCL2 protein]; fumonisin B1 promotes the reaction [Zearalenone results in decreased expression of BCL2 mRNA]; ochratoxin A promotes the reaction [fumonisin B1 results in decreased expression of BCL2 mRNA]; ochratoxin A promotes the reaction [fumonisin B1 results in decreased expression of BCL2 protein]; pyrazolanthrone inhibits the reaction [[fumonisin B1 co-treated with ochratoxin A] results in decreased expression of BCL2 mRNA]; Zearalenone inhibits the reaction [fumonisin B1 inhibits the reaction [deoxynivalenol results in decreased expression of BCL2 protein]]; Zearalenone inhibits the reaction [fumonisin B1 promotes the reaction [Zearalenone results in decreased expression of BCL2 mRNA]] |
CTD |
PMID:29109043 PMID:33905761 PMID:36397609 |
|
NCBI chr 1:158,337,403...158,518,214
Ensembl chr 1:158,337,522...158,518,879
|
|
G |
CASP1 |
caspase 1, apoptosis-related cysteine peptidase |
multiple interactions |
EXP |
N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [[fumonisin B1 co-treated with deoxynivalenol] results in increased expression of CASP1 mRNA]; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [[fumonisin B1 co-treated with deoxynivalenol] results in increased expression of CASP1 protein] |
CTD |
PMID:36309173 |
|
NCBI chr 9:35,188,066...35,199,364
Ensembl chr 9:35,186,420...35,200,328
|
|
G |
CASP10 |
caspase 10 |
multiple interactions increases expression |
EXP |
3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [fumonisin B1 results in increased expression of CASP10 mRNA] |
CTD |
PMID:32198028 |
|
NCBI chr15:104,858,082...104,895,941
Ensembl chr15:104,858,100...104,894,933
|
|
G |
CASP3 |
caspase 3 |
multiple interactions increases expression |
EXP |
3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [fumonisin B1 results in increased expression of CASP3 mRNA]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [fumonisin B1 results in increased expression of CASP3 protein]; [fumonisin B1 co-treated with deoxynivalenol] results in increased expression of CASP3 mRNA; [fumonisin B1 co-treated with deoxynivalenol] results in increased expression of CASP3 protein; [fumonisin B1 co-treated with ochratoxin A] results in increased expression of CASP3 mRNA; [fumonisin B1 co-treated with ochratoxin A] results in increased expression of CASP3 protein; [fumonisin B1 co-treated with ochratoxin A] results in increased expression of CASP3 protein modified form; [fumonisin B1 co-treated with Zearalenone] promotes the reaction [deoxynivalenol results in increased expression of CASP3 protein]; [fumonisin B1 co-treated with Zearalenone] results in increased expression of CASP3 mRNA; [fumonisin B1 co-treated with Zearalenone] results in increased expression of CASP3 protein; Acetylcysteine inhibits the reaction [[fumonisin B1 co-treated with ochratoxin A] results in increased expression of CASP3 mRNA]; Acetylcysteine inhibits the reaction [[fumonisin B1 co-treated with ochratoxin A] results in increased expression of CASP3 protein modified form]; Acetylcysteine inhibits the reaction [[fumonisin B1 co-treated with ochratoxin A] results in increased expression of CASP3 protein]; Acetylcysteine inhibits the reaction [[fumonisin B1 co-treated with Zearalenone] promotes the reaction [deoxynivalenol results in increased expression of CASP3 protein]]; Acetylcysteine inhibits the reaction [[fumonisin B1 co-treated with Zearalenone] results in increased expression of CASP3 protein]; Acetylcysteine inhibits the reaction [deoxynivalenol promotes the reaction [[fumonisin B1 co-treated with Zearalenone] results in increased expression of CASP3 mRNA]]; Acetylcysteine inhibits the reaction [Zearalenone promotes the reaction [[fumonisin B1 co-treated with deoxynivalenol] results in increased expression of CASP3 mRNA]]; deoxynivalenol promotes the reaction [[fumonisin B1 co-treated with Zearalenone] results in increased expression of CASP3 mRNA]; fumonisin B1 promotes the reaction [deoxynivalenol promotes the reaction [Zearalenone results in increased expression of CASP3 mRNA]]; fumonisin B1 promotes the reaction [ochratoxin A results in increased cleavage of CASP3 protein]; fumonisin B1 promotes the reaction [ochratoxin A results in increased expression of CASP3 mRNA]; fumonisin B1 promotes the reaction [ochratoxin A results in increased expression of CASP3 protein modified form]; fumonisin B1 promotes the reaction [ochratoxin A results in increased expression of CASP3 protein]; fumonisin B1 promotes the reaction [Zearalenone promotes the reaction [deoxynivalenol results in increased expression of CASP3 mRNA]]; ochratoxin A promotes the reaction [fumonisin B1 results in increased expression of CASP3 mRNA]; ochratoxin A promotes the reaction [fumonisin B1 results in increased expression of CASP3 protein modified form]; ochratoxin A promotes the reaction [fumonisin B1 results in increased expression of CASP3 protein]; pyrazolanthrone inhibits the reaction [[fumonisin B1 co-treated with ochratoxin A] results in increased expression of CASP3 mRNA]; pyrazolanthrone inhibits the reaction [[fumonisin B1 co-treated with ochratoxin A] results in increased expression of CASP3 protein modified form]; pyrazolanthrone inhibits the reaction [[fumonisin B1 co-treated with ochratoxin A] results in increased expression of CASP3 protein]; Zearalenone promotes the reaction [[fumonisin B1 co-treated with deoxynivalenol] results in increased expression of CASP3 mRNA] fumonisin B1 results in increased expression of CASP3 mRNA; fumonisin B1 results in increased expression of CASP3 protein; fumonisin B1 results in increased expression of CASP3 protein modified form |
CTD |
PMID:29109043 PMID:32198028 PMID:33905761 PMID:36397609 |
|
NCBI chr15:45,744,320...45,753,252
Ensembl chr15:45,742,751...45,764,213
|
|
G |
CASP8 |
caspase 8 |
multiple interactions increases expression |
EXP |
3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [fumonisin B1 results in increased expression of CASP8 mRNA] |
CTD |
PMID:32198028 |
|
NCBI chr15:104,923,659...104,948,470
Ensembl chr15:104,923,953...104,948,468
|
|
G |
CASP9 |
caspase 9 |
multiple interactions increases expression |
EXP |
[fumonisin B1 co-treated with ochratoxin A] results in increased expression of CASP9 mRNA; [fumonisin B1 co-treated with ochratoxin A] results in increased expression of CASP9 protein; [fumonisin B1 co-treated with ochratoxin A] results in increased expression of CASP9 protein modified form; Acetylcysteine inhibits the reaction [[fumonisin B1 co-treated with ochratoxin A] results in increased expression of CASP9 mRNA]; Acetylcysteine inhibits the reaction [[fumonisin B1 co-treated with ochratoxin A] results in increased expression of CASP9 protein modified form]; Acetylcysteine inhibits the reaction [[fumonisin B1 co-treated with ochratoxin A] results in increased expression of CASP9 protein]; fumonisin B1 promotes the reaction [ochratoxin A results in increased expression of CASP9 mRNA]; fumonisin B1 promotes the reaction [ochratoxin A results in increased expression of CASP9 protein modified form]; fumonisin B1 promotes the reaction [ochratoxin A results in increased expression of CASP9 protein]; ochratoxin A promotes the reaction [fumonisin B1 results in increased expression of CASP9 mRNA]; ochratoxin A promotes the reaction [fumonisin B1 results in increased expression of CASP9 protein modified form]; ochratoxin A promotes the reaction [fumonisin B1 results in increased expression of CASP9 protein]; pyrazolanthrone inhibits the reaction [[fumonisin B1 co-treated with ochratoxin A] results in increased expression of CASP9 mRNA]; pyrazolanthrone inhibits the reaction [[fumonisin B1 co-treated with ochratoxin A] results in increased expression of CASP9 protein modified form]; pyrazolanthrone inhibits the reaction [[fumonisin B1 co-treated with ochratoxin A] results in increased expression of CASP9 protein] fumonisin B1 results in increased expression of CASP9 mRNA; fumonisin B1 results in increased expression of CASP9 protein; fumonisin B1 results in increased expression of CASP9 protein modified form |
CTD |
PMID:33905761 PMID:36397609 |
|
NCBI chr 6:74,707,597...74,730,033
Ensembl chr 6:74,706,516...74,730,007
|
|
G |
CCL2 |
chemokine (C-C motif) ligand 2 |
multiple interactions increases expression decreases expression |
EXP |
[deoxynivalenol co-treated with fumonisin B1] results in increased expression of CCL2 mRNA; [deoxynivalenol co-treated with nivalenol co-treated with fumonisin B1] results in increased expression of CCL2 mRNA; [deoxynivalenol co-treated with nivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of CCL2 mRNA; [deoxynivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of CCL2 mRNA; [nivalenol co-treated with fumonisin B1] results in increased expression of CCL2 mRNA; [Zearalenone co-treated with fumonisin B1] results in increased expression of CCL2 mRNA; fumonisin B1 metabolite inhibits the reaction [[deoxynivalenol co-treated with Lipopolysaccharides] results in increased expression of CCL2 mRNA]; fumonisin B1 promotes the reaction [[deoxynivalenol co-treated with Lipopolysaccharides] results in increased expression of CCL2 mRNA] fumonisin B1 metabolite results in increased expression of CCL2 mRNA; fumonisin B1 results in increased expression of CCL2 mRNA fumonisin B1 results in decreased expression of CCL2 mRNA |
CTD |
PMID:23688591 PMID:30708112 |
|
NCBI chr12:40,798,109...40,800,013
Ensembl chr12:40,798,109...40,800,026
|
|
G |
CCL20 |
C-C motif chemokine ligand 20 |
increases expression multiple interactions |
EXP |
fumonisin B1 results in increased expression of CCL20 mRNA fumonisin B1 metabolite inhibits the reaction [[deoxynivalenol co-treated with Lipopolysaccharides] results in increased expression of CCL20 mRNA]; fumonisin B1 promotes the reaction [[deoxynivalenol co-treated with Lipopolysaccharides] results in increased expression of CCL20 mRNA] |
CTD |
PMID:30708112 |
|
NCBI chr15:129,172,743...129,176,069
|
|
G |
CHUK |
component of inhibitor of nuclear factor kappa B kinase complex |
increases expression |
EXP |
fumonisin B1 results in increased expression of CHUK mRNA |
CTD |
PMID:32198028 |
|
NCBI chr14:111,316,178...111,351,669
Ensembl chr14:111,315,141...111,351,868
|
|
G |
CLDN1 |
claudin 1 |
decreases expression |
EXP |
fumonisin B1 results in decreased expression of CLDN1 mRNA; fumonisin B1 results in decreased expression of CLDN1 protein |
CTD |
PMID:31557363 |
|
NCBI chr13:127,714,857...127,730,628
Ensembl chr13:127,712,777...127,730,657
|
|
G |
CXCL8 |
C-X-C motif chemokine ligand 8 |
multiple interactions increases expression |
EXP |
[deoxynivalenol co-treated with fumonisin B1] results in increased expression of CXCL8 mRNA; [deoxynivalenol co-treated with nivalenol co-treated with fumonisin B1] results in increased expression of CXCL8 mRNA; [deoxynivalenol co-treated with nivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of CXCL8 mRNA; [deoxynivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of CXCL8 mRNA; [nivalenol co-treated with fumonisin B1] results in increased expression of CXCL8 mRNA; [nivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of CXCL8 mRNA; [Zearalenone co-treated with fumonisin B1] results in increased expression of CXCL8 mRNA; fumonisin B1 metabolite inhibits the reaction [[deoxynivalenol co-treated with Lipopolysaccharides] results in increased expression of CXCL8 mRNA]; fumonisin B1 promotes the reaction [[deoxynivalenol co-treated with Lipopolysaccharides] results in increased expression of CXCL8 mRNA] fumonisin B1 results in increased expression of CXCL8 mRNA |
CTD |
PMID:23688591 PMID:30708112 |
|
NCBI chr 8:69,932,646...69,935,861
Ensembl chr 8:69,932,643...69,935,861
|
|
G |
CYCS |
cytochrome c, somatic |
multiple interactions |
EXP |
[deoxynivalenol co-treated with fumonisin B1] results in increased expression of CYCS mRNA; [Zearalenone co-treated with fumonisin B1] results in increased expression of CYCS mRNA; Acetylcysteine inhibits the reaction [deoxynivalenol promotes the reaction [[Zearalenone co-treated with fumonisin B1] results in increased expression of CYCS mRNA]]; Acetylcysteine inhibits the reaction [fumonisin B1 promotes the reaction [deoxynivalenol promotes the reaction [Zearalenone results in increased expression of CYCS mRNA]]]; Acetylcysteine inhibits the reaction [Zearalenone promotes the reaction [[deoxynivalenol co-treated with fumonisin B1] results in increased expression of CYCS mRNA]]; deoxynivalenol promotes the reaction [[Zearalenone co-treated with fumonisin B1] results in increased expression of CYCS mRNA]; fumonisin B1 promotes the reaction [deoxynivalenol promotes the reaction [Zearalenone results in increased expression of CYCS mRNA]]; fumonisin B1 promotes the reaction [ochratoxin A results in increased expression of CYCS mRNA]; Zearalenone promotes the reaction [[deoxynivalenol co-treated with fumonisin B1] results in increased expression of CYCS mRNA] |
CTD |
PMID:29109043 PMID:36397609 |
|
NCBI chr18:47,169,921...47,172,212
Ensembl chr18:47,169,866...47,173,866
|
|
G |
GSDMD |
gasdermin D |
multiple interactions |
EXP |
belnacasan inhibits the reaction [[fumonisin B1 co-treated with deoxynivalenol] results in increased expression of GSDMD mRNA]; belnacasan inhibits the reaction [[fumonisin B1 co-treated with deoxynivalenol] results in increased expression of GSDMD protein]; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [[fumonisin B1 co-treated with deoxynivalenol] results in increased expression of GSDMD mRNA]; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [[fumonisin B1 co-treated with deoxynivalenol] results in increased expression of GSDMD protein] |
CTD |
PMID:36309173 |
|
NCBI chr 4:995,753...1,001,964
Ensembl chr 4:995,763...1,000,271
|
|
G |
GSR |
glutathione-disulfide reductase |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [fumonisin B1 promotes the reaction [deoxynivalenol results in decreased activity of GSR protein]]; Acetylcysteine inhibits the reaction [fumonisin B1 promotes the reaction [Zearalenone promotes the reaction [deoxynivalenol results in decreased activity of GSR protein]]]; Acetylcysteine inhibits the reaction [Zearalenone promotes the reaction [fumonisin B1 promotes the reaction [deoxynivalenol results in decreased activity of GSR protein]]]; fumonisin B1 promotes the reaction [deoxynivalenol results in decreased activity of GSR protein]; fumonisin B1 promotes the reaction [Zearalenone promotes the reaction [deoxynivalenol results in decreased activity of GSR protein]]; Zearalenone promotes the reaction [fumonisin B1 promotes the reaction [deoxynivalenol results in decreased activity of GSR protein]] |
CTD |
PMID:29109043 |
|
NCBI chr15:54,382,564...54,433,989
Ensembl chr15:54,382,567...54,433,984
|
|
G |
HAVCR1 |
hepatitis A virus cellular receptor 1 |
multiple interactions |
EXP |
[fumonisin B1 co-treated with ochratoxin A] results in increased expression of HAVCR1 mRNA |
CTD |
PMID:33905761 |
|
NCBI chr16:66,162,318...66,208,868
|
|
G |
IFNG |
interferon gamma |
decreases expression |
EXP |
fumonisin B1 metabolite results in decreased expression of IFNG protein |
CTD |
PMID:30708112 |
|
NCBI chr 5:32,477,906...32,482,670
Ensembl chr 5:32,477,906...32,482,670
|
|
G |
IL17A |
interleukin 17A |
multiple interactions |
EXP |
fumonisin B1 inhibits the reaction [[deoxynivalenol co-treated with Lipopolysaccharides] results in increased expression of IL17A protein]; fumonisin B1 metabolite inhibits the reaction [[deoxynivalenol co-treated with Lipopolysaccharides] results in increased expression of IL17A protein] |
CTD |
PMID:30708112 |
|
NCBI chr 7:46,013,584...46,017,161
Ensembl chr 7:46,013,584...46,017,153
|
|
G |
IL18 |
interleukin 18 |
multiple interactions |
EXP |
belnacasan inhibits the reaction [[fumonisin B1 co-treated with deoxynivalenol] results in increased expression of IL18 mRNA]; belnacasan inhibits the reaction [[fumonisin B1 co-treated with deoxynivalenol] results in increased expression of IL18 protein]; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [[fumonisin B1 co-treated with deoxynivalenol] results in increased expression of IL18 mRNA]; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [[fumonisin B1 co-treated with deoxynivalenol] results in increased expression of IL18 protein] |
CTD |
PMID:36309173 |
|
NCBI chr 9:39,839,959...39,861,258
Ensembl chr 9:39,834,973...39,861,219
|
|
G |
IL1A |
interleukin 1 alpha |
multiple interactions decreases expression increases expression |
EXP |
[deoxynivalenol co-treated with fumonisin B1] results in decreased expression of IL1A mRNA; [deoxynivalenol co-treated with nivalenol co-treated with fumonisin B1] results in increased expression of IL1A mRNA; [deoxynivalenol co-treated with nivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of IL1A mRNA; [deoxynivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of IL1A mRNA; [nivalenol co-treated with fumonisin B1] results in increased expression of IL1A mRNA; [nivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of IL1A mRNA; [Zearalenone co-treated with fumonisin B1] results in increased expression of IL1A mRNA fumonisin B1 results in decreased expression of IL1A mRNA fumonisin B1 results in increased expression of IL1A mRNA |
CTD |
PMID:23688591 |
|
NCBI chr 3:43,718,320...43,731,668
Ensembl chr 3:43,718,368...43,731,119
|
|
G |
IL6 |
interleukin 6 |
multiple interactions increases expression decreases expression |
EXP |
[deoxynivalenol co-treated with fumonisin B1] results in increased expression of IL6 mRNA; [deoxynivalenol co-treated with nivalenol co-treated with fumonisin B1] results in increased expression of IL6 mRNA; [deoxynivalenol co-treated with nivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of IL6 mRNA; [deoxynivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of IL6 mRNA; [nivalenol co-treated with fumonisin B1] results in decreased expression of IL6 mRNA; [nivalenol co-treated with fumonisin B1] results in increased expression of IL6 mRNA; [nivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of IL6 mRNA; [Zearalenone co-treated with fumonisin B1] results in increased expression of IL6 mRNA fumonisin B1 results in increased expression of IL6 mRNA fumonisin B1 results in decreased expression of IL6 mRNA |
CTD |
PMID:23688591 PMID:30708112 |
|
NCBI chr 9:91,506,421...91,510,830
Ensembl chr 9:91,506,421...91,511,263
|
|
G |
LCN2 |
lipocalin 2 |
multiple interactions |
EXP |
[fumonisin B1 co-treated with ochratoxin A] results in increased expression of LCN2 mRNA |
CTD |
PMID:33905761 |
|
NCBI chr 1:268,609,975...268,614,651
Ensembl chr 1:268,609,887...268,614,644
|
|
G |
LOC110258578 |
interleukin-1 beta-like |
increases expression multiple interactions |
EXP |
fumonisin B1 results in increased expression of IL1B mRNA [deoxynivalenol co-treated with fumonisin B1] results in increased expression of IL1B mRNA; [deoxynivalenol co-treated with nivalenol co-treated with fumonisin B1] results in increased expression of IL1B mRNA; [deoxynivalenol co-treated with nivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of IL1B mRNA; [deoxynivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of IL1B mRNA; [nivalenol co-treated with fumonisin B1] results in increased expression of IL1B mRNA; [nivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of IL1B mRNA; [Zearalenone co-treated with fumonisin B1] results in increased expression of IL1B mRNA; belnacasan inhibits the reaction [[fumonisin B1 co-treated with deoxynivalenol] results in increased expression of IL1B mRNA]; belnacasan inhibits the reaction [[fumonisin B1 co-treated with deoxynivalenol] results in increased expression of IL1B protein]; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [[fumonisin B1 co-treated with deoxynivalenol] results in increased expression of IL1B mRNA]; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [[fumonisin B1 co-treated with deoxynivalenol] results in increased expression of IL1B protein] |
CTD |
PMID:23688591 PMID:36309173 |
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MAP3K14 |
mitogen-activated protein kinase kinase kinase 14 |
increases expression |
EXP |
fumonisin B1 results in increased expression of MAP3K14 mRNA |
CTD |
PMID:32198028 |
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NCBI chr12:18,142,899...18,182,931
Ensembl chr12:18,142,952...18,182,928
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G |
MAPK1 |
mitogen-activated protein kinase 1 |
increases phosphorylation |
EXP |
fumonisin B1 results in increased phosphorylation of MAPK1 protein |
CTD |
PMID:31557363 |
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NCBI chr14:50,083,079...50,165,528
Ensembl chr14:50,082,896...50,165,513
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G |
MAPK10 |
mitogen-activated protein kinase 10 |
increases expression multiple interactions |
EXP |
fumonisin B1 results in increased expression of MAPK10 mRNA 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [fumonisin B1 results in increased expression of MAPK10 mRNA] |
CTD |
PMID:32198028 |
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NCBI chr 8:132,445,818...132,751,575
Ensembl chr 8:132,298,299...132,776,820
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G |
MAPK3 |
mitogen-activated protein kinase 3 |
increases phosphorylation |
EXP |
fumonisin B1 results in increased phosphorylation of MAPK3 protein |
CTD |
PMID:31557363 |
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NCBI chr 3:18,291,444...18,299,410
Ensembl chr 3:18,291,445...18,299,567
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G |
MAPK8 |
mitogen-activated protein kinase 8 |
increases expression multiple interactions |
EXP |
fumonisin B1 results in increased expression of MAPK8 mRNA; fumonisin B1 results in increased expression of MAPK8 protein 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [fumonisin B1 results in increased expression of MAPK8 mRNA]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [fumonisin B1 results in increased expression of MAPK8 protein] |
CTD |
PMID:32198028 |
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NCBI chr14:88,988,914...89,108,875
Ensembl chr14:88,988,949...89,108,874
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G |
MAPK9 |
mitogen-activated protein kinase 9 |
increases expression multiple interactions |
EXP |
fumonisin B1 results in increased expression of MAPK9 mRNA 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [fumonisin B1 results in increased expression of MAPK9 mRNA] |
CTD |
PMID:32198028 |
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NCBI chr 2:78,338,466...78,399,108
Ensembl chr 2:78,338,376...78,399,100
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G |
MUC1 |
mucin 1, cell surface associated |
decreases expression |
EXP |
fumonisin B1 results in decreased expression of MUC1 mRNA |
CTD |
PMID:31557363 |
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NCBI chr 4:94,626,317...94,631,194
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G |
MUC2 |
mucin 2, oligomeric mucus/gel-forming |
increases expression |
EXP |
fumonisin B1 results in increased expression of MUC2 mRNA |
CTD |
PMID:31557363 |
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NCBI chr 2:689,363...719,542
Ensembl chr 2:689,364...710,330
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G |
NFKB1 |
nuclear factor kappa B subunit 1 |
increases expression multiple interactions |
EXP |
fumonisin B1 results in increased expression of NFKB1 mRNA; fumonisin B1 results in increased expression of NFKB1 protein 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [fumonisin B1 results in increased expression of NFKB1 mRNA]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [fumonisin B1 results in increased expression of NFKB1 protein] |
CTD |
PMID:32198028 |
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NCBI chr 8:118,391,010...118,478,927
Ensembl chr 8:118,390,638...118,506,691
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G |
NTN1 |
netrin 1 |
multiple interactions |
EXP |
fumonisin B1 promotes the reaction [ochratoxin A results in increased expression of NTN1 mRNA] |
CTD |
PMID:33905761 |
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NCBI chr12:54,089,444...54,292,191
Ensembl chr12:54,089,472...54,292,193
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OCLN |
occludin |
decreases expression |
EXP |
fumonisin B1 results in decreased expression of OCLN mRNA; fumonisin B1 results in decreased expression of OCLN protein |
CTD |
PMID:31557363 |
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NCBI chr16:47,600,175...47,652,435
Ensembl chr16:47,600,212...47,654,033
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G |
SLC15A1 |
solute carrier family 15 member 1 |
increases expression |
EXP |
fumonisin B1 results in increased expression of SLC15A1 mRNA |
CTD |
PMID:33443779 |
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NCBI chr11:67,652,808...67,690,457
Ensembl chr11:67,652,193...67,710,933
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G |
SLC1A1 |
solute carrier family 1 member 1 |
decreases expression |
EXP |
fumonisin B1 results in decreased expression of SLC1A1 mRNA |
CTD |
PMID:33443779 |
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NCBI chr 1:217,366,493...217,441,643
Ensembl chr 1:217,366,499...217,441,674
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G |
SLC27A4 |
solute carrier family 27 member 4 |
decreases expression |
EXP |
fumonisin B1 results in decreased expression of SLC27A4 mRNA |
CTD |
PMID:33443779 |
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NCBI chr 1:268,773,792...268,788,208
Ensembl chr 1:268,773,806...268,788,731
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G |
SLC2A2 |
solute carrier family 2 member 2 |
decreases expression |
EXP |
fumonisin B1 results in decreased expression of SLC2A2 mRNA |
CTD |
PMID:33443779 |
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NCBI chr13:109,592,595...109,614,105
Ensembl chr13:109,587,258...109,638,510
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G |
SLC7A1 |
solute carrier family 7 member 1 |
decreases expression |
EXP |
fumonisin B1 results in decreased expression of SLC7A1 mRNA |
CTD |
PMID:33443779 |
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NCBI chr11:6,538,053...6,604,654
Ensembl chr11:6,538,045...6,604,658
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SLC7A7 |
solute carrier family 7 member 7 |
decreases expression |
EXP |
fumonisin B1 results in decreased expression of SLC7A7 mRNA |
CTD |
PMID:33443779 |
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NCBI chr 7:76,195,774...76,235,406
Ensembl chr 7:76,198,256...76,235,402
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G |
SPP1 |
secreted phosphoprotein 1 |
increases expression multiple interactions |
EXP |
fumonisin B1 results in increased expression of SPP1 mRNA fumonisin B1 promotes the reaction [ochratoxin A results in increased expression of SPP1 mRNA]; ochratoxin A promotes the reaction [fumonisin B1 results in increased expression of SPP1 mRNA] |
CTD |
PMID:33905761 |
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NCBI chr 8:131,077,786...131,085,334
Ensembl chr 8:131,077,786...131,085,340
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G |
TJP1 |
tight junction protein 1 |
decreases expression |
EXP |
fumonisin B1 results in decreased expression of TJP1 mRNA; fumonisin B1 results in decreased expression of TJP1 protein |
CTD |
PMID:31557363 |
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NCBI chr 1:144,930,387...145,195,857
Ensembl chr 1:144,930,370...145,195,836
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G |
TNF |
tumor necrosis factor |
multiple interactions increases expression |
EXP |
[deoxynivalenol co-treated with fumonisin B1] results in increased expression of TNF mRNA; [deoxynivalenol co-treated with Lipopolysaccharides co-treated with fumonisin B1] results in increased expression of TNF mRNA; [deoxynivalenol co-treated with Lipopolysaccharides co-treated with fumonisin B1] results in increased expression of TNF protein; [deoxynivalenol co-treated with nivalenol co-treated with fumonisin B1] results in increased expression of TNF mRNA; [deoxynivalenol co-treated with nivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of TNF mRNA; [deoxynivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of TNF mRNA; [nivalenol co-treated with fumonisin B1] results in increased expression of TNF mRNA; [nivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of TNF mRNA; [Zearalenone co-treated with fumonisin B1] results in increased expression of TNF mRNA fumonisin B1 results in increased expression of TNF mRNA; fumonisin B1 results in increased expression of TNF protein |
CTD |
PMID:23688591 PMID:30708112 PMID:32198028 |
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NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,628...23,702,416
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TP53 |
tumor protein p53 |
increases expression multiple interactions |
EXP |
fumonisin B1 results in increased expression of TP53 mRNA [deoxynivalenol co-treated with fumonisin B1] results in increased expression of TP53 mRNA; Acetylcysteine inhibits the reaction [fumonisin B1 promotes the reaction [Zearalenone results in increased expression of TP53 mRNA]]; Acetylcysteine inhibits the reaction [Zearalenone promotes the reaction [fumonisin B1 results in increased expression of TP53 mRNA]]; fumonisin B1 inhibits the reaction [deoxynivalenol inhibits the reaction [Zearalenone results in increased expression of TP53 mRNA]]; fumonisin B1 promotes the reaction [Zearalenone results in increased expression of TP53 mRNA]; Zearalenone promotes the reaction [[deoxynivalenol co-treated with fumonisin B1] results in increased expression of TP53 mRNA]; Zearalenone promotes the reaction [fumonisin B1 results in increased expression of TP53 mRNA] |
CTD |
PMID:29109043 |
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NCBI chr12:52,939,643...52,953,786
Ensembl chr12:52,939,644...52,953,818
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TRADD |
TNFRSF1A associated via death domain |
increases expression |
EXP |
fumonisin B1 results in increased expression of TRADD mRNA |
CTD |
PMID:32198028 |
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NCBI chr 6:27,797,594...27,804,654
Ensembl chr 6:27,797,607...27,804,423
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G |
TRAF2 |
TNF receptor associated factor 2 |
increases expression |
EXP |
fumonisin B1 results in increased expression of TRAF2 mRNA |
CTD |
PMID:32198028 |
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FOS |
Fos proto-oncogene, AP-1 transcription factor subunit |
increases expression multiple interactions |
EXP |
Serotonin results in increased expression of FOS mRNA; Serotonin results in increased expression of FOS protein sarpogrelate inhibits the reaction [Serotonin results in increased expression of FOS mRNA]; sarpogrelate inhibits the reaction [Serotonin results in increased expression of FOS protein] |
CTD |
PMID:11426759 |
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NCBI chr 7:98,449,508...98,451,971
Ensembl chr 7:98,449,349...98,455,554
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G |
JUN |
Jun proto-oncogene, AP-1 transcription factor subunit |
multiple interactions increases expression |
EXP |
sarpogrelate inhibits the reaction [Serotonin results in increased expression of JUN mRNA]; sarpogrelate inhibits the reaction [Serotonin results in increased expression of JUN protein] Serotonin results in increased expression of JUN mRNA; Serotonin results in increased expression of JUN protein |
CTD |
PMID:11426759 |
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NCBI chr 6:153,686,425...153,687,635
Ensembl chr 6:153,685,682...153,687,636
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G |
MAPK1 |
mitogen-activated protein kinase 1 |
increases phosphorylation multiple interactions |
EXP |
Serotonin results in increased phosphorylation of MAPK1 protein sarpogrelate inhibits the reaction [Serotonin results in increased phosphorylation of MAPK1 protein] |
CTD |
PMID:11426759 |
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NCBI chr14:50,083,079...50,165,528
Ensembl chr14:50,082,896...50,165,513
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G |
MAPK3 |
mitogen-activated protein kinase 3 |
multiple interactions increases phosphorylation |
EXP |
sarpogrelate inhibits the reaction [Serotonin results in increased phosphorylation of MAPK3 protein] |
CTD |
PMID:11426759 |
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NCBI chr 3:18,291,444...18,299,410
Ensembl chr 3:18,291,445...18,299,567
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