Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:serotonin uptake inhibitor
go back to main search page
Accession:CHEBI:50949 term browser browse the term
Definition:A compound that specifically inhibits the reuptake of serotonin in the brain. This increases the serotonin concentration in the synaptic cleft which then activates serotonin receptors to a greater extent.
Synonyms:related_synonym: SSRI;   serotonin reuptake inhibitor
 xref: Wikipedia:Selective_serotonin_reuptake_inhibitor


show annotations for term's descendants           Sort by:


Your selection has 3462 annotated objects. The maximum number of objects that can be shown is 2000. The list is too large to display.

  • Select a more specific term using the term browser
  • Download the entire list for this term
  • Display annotations for this term only (exclude descendants)


    • Term paths to the root
    Path 1
    Term Annotations click to browse term
      CHEBI ontology 19932
        role 19904
          biological role 19902
            pharmacological role 19120
              neurotransmitter agent 16808
                serotonergic drug 4340
                  serotonin uptake inhibitor 3462
                    (R)-fluoxetine + 400
                    (R)-fluoxetine hydrochloride + 1
                    (R,R)-tramadol + 38
                    (R,R)-tramadol hydrochloride + 0
                    (S)-fenfluramine + 2
                    (S)-fenfluramine hydrochloride 0
                    (S)-fluoxetine + 400
                    (S)-fluoxetine hydrochloride + 1
                    (S,S)-tramadol + 38
                    (S,S)-tramadol hydrochloride + 0
                    LY-367,265 0
                    N-methylparoxetine 0
                    amoxapine 8
                    chlorphenamine + 14
                    citalopram 50
                    citalopram hydrobromide 0
                    clomipramine 93
                    cocaine 1448
                    desipramine + 51
                    escitalopram hydrobromide + 0
                    fenfluramine + 42
                    fenfluramine hydrochloride + 0
                    fluoxetine 400
                    fluoxetine hydrochloride 1
                    fluvoxamine 20
                    methadone + 32
                    minaprine + 0
                    nefazodone + 1760
                    nefopam 1
                    nefopam hydrochloride 0
                    noribogaine 0
                    olanzapine 149
                    paroxetine + 50
                    paroxetine hydrochloride 0
                    paroxetine maleate 0
                    sertraline 130
                    sertraline hydrochloride 0
                    sibutramine 11
                    tramadol 38
                    tramadol hydrochloride 0
                    trazodone + 24
                    trazodone hydrochloride 0
                    venlafaxine + 182
                    vilazodone 0
                    vilazodone hydrochloride 0
    Path 2
    Term Annotations click to browse term
      CHEBI ontology 19932
        role 19904
          application 19741
            pharmaceutical 19579
              drug 19579
                neurotransmitter agent 16808
                  serotonergic drug 4340
                    serotonin uptake inhibitor 3462
                      (R)-fluoxetine + 400
                      (R)-fluoxetine hydrochloride + 1
                      (R,R)-tramadol + 38
                      (R,R)-tramadol hydrochloride + 0
                      (S)-fenfluramine + 2
                      (S)-fenfluramine hydrochloride 0
                      (S)-fluoxetine + 400
                      (S)-fluoxetine hydrochloride + 1
                      (S,S)-tramadol + 38
                      (S,S)-tramadol hydrochloride + 0
                      LY-367,265 0
                      N-methylparoxetine 0
                      amoxapine 8
                      chlorphenamine + 14
                      citalopram 50
                      citalopram hydrobromide 0
                      clomipramine 93
                      cocaine 1448
                      desipramine + 51
                      escitalopram hydrobromide + 0
                      fenfluramine + 42
                      fenfluramine hydrochloride + 0
                      fluoxetine 400
                      fluoxetine hydrochloride 1
                      fluvoxamine 20
                      methadone + 32
                      minaprine + 0
                      nefazodone + 1760
                      nefopam 1
                      nefopam hydrochloride 0
                      noribogaine 0
                      olanzapine 149
                      paroxetine + 50
                      paroxetine hydrochloride 0
                      paroxetine maleate 0
                      sertraline 130
                      sertraline hydrochloride 0
                      sibutramine 11
                      tramadol 38
                      tramadol hydrochloride 0
                      trazodone + 24
                      trazodone hydrochloride 0
                      venlafaxine + 182
                      vilazodone 0
                      vilazodone hydrochloride 0
    paths to the root