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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:azaphilone
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Accession:CHEBI:50941 term browser browse the term
Definition:Any member of a family of natural products which contains a 6H-isochromene-6,8(7H)-dione or an isoquinoline-6,8(2H,7H)-dione skeleton and its substituted derivatives thereof.
Synonyms:related_synonym: azaphilone natural products;   azaphilones


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chaetomugilin D term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnf tumor necrosis factor multiple interactions ISO chaetomugilin D results in increased expression of and results in increased secretion of TNF protein CTD PMID:28535995 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19911
    role 19886
      biological role 19884
        biochemical role 19575
          metabolite 19560
            eukaryotic metabolite 19369
              fungal metabolite 17761
                azaphilone 1
                  (-)-rotiorin 0
                  (7R,8R)-7,8-Dihydroxy-3,5,7-trimethyl-8H-isochromen-6-one 0
                  12beta-hydroxychaetoviridin C 0
                  2-thiophenecarboxylic acid [3-(4-methoxy-4-oxobutyl)-7-methyl-6,8-dioxo-2-phenyl-7-isoquinolinyl] ester 0
                  3-(3,4-Dihydroxy-3,5-dimethylhept-1-enyl)-7,8-dihydroxy-7-methyl-8,8a-dihydro-1H-isochromen-6-one 0
                  3-phenylpropanoic acid [3-(4-cyanophenyl)-2-cyclohexyl-7-methyl-6,8-dioxo-7-isoquinolinyl] ester 0
                  3-phenylpropanoic acid [3-(4-cyanophenyl)-7-methyl-6,8-dioxo-2-[2-(2-pyridinyl)ethyl]-7-isoquinolinyl] ester 0
                  4'-epichaetoviridin A 0
                  4'-epichaetoviridin F 0
                  5'-epichaetoviridin A 0
                  5-Chloro-3-[(E)-3,4-dihydroxy-3,5-dimethylhept-1-enyl]-7,8-dihydroxy-7-methyl-8,8a-dihydro-1H-isochromen-6-one 0
                  5-Chloro-3-[(E)-3,4-dihydroxy-3,5-dimethylhept-1-enyl]-7,8-dihydroxy-7-methyl-8H-isochromen-6-one 0
                  7,8-Dihydroxy-3,7-dimethyl-6-oxo-7,8-dihydro-6H-isochromene-5-carbaldehyde 0
                  7,8-dihydroxy-3,5,7-trimethyl-8,8a-dihydro-1H-isochromen-6-one 0
                  Austdiol 0
                  Berkazaphilone A 0
                  CT2108A 0
                  CT2108B 0
                  Dihydrodeoxy-8-epiaustdiol 0
                  Sclerotiorin 0
                  [(6R,7R)-7-hydroxy-7-methyl-8-oxo-3-[(E)-prop-1-enyl]-5,6-dihydro-1H-isochromen-6-yl] 3,6-dihydroxy-4-methoxy-2-methylbenzoate 0
                  [5-Chloranyl-3-[(1E,3E)-3,5-dimethylhepta-1,3-dienyl]-7-methyl-6,8-bis(oxidanylidene)isochromen-7-yl] ethanoate 0
                  [7-hydroxy-7-methyl-8-oxo-3-[(E)-prop-1-enyl]-5,6-dihydro-1H-isochromen-6-yl] 2-hydroxy-4-methoxy-6-methylbenzoate 0
                  acetic acid [5-chloro-3-(3,5-dimethylhepta-1,3-dienyl)-7-methyl-6,8-dioxo-2-benzopyran-7-yl] ester 0
                  azanigerone A 0
                  azanigerone B 0
                  azanigerone C 0
                  azanigerone D 0
                  azanigerone E 0
                  azanigerone F 0
                  chaetomugilin A 0
                  chaetomugilin D 1
                  chaetoviridin A 0
                  chaetoviridin C + 0
                  chaetoviridin E 0
                  chaetoviridin G 0
                  chaetoviridin H 0
                  chaetoviridin I 0
                  chermesinone A 0
                  chermesinone B 0
                  chermesinone C 0
                  comazaphilone A 0
                  comazaphilone B 0
                  comazaphilone C 0
                  comazaphilone D 0
                  comazaphilone E 0
                  comazaphilone F 0
                  epi-isochromophilone II 0
                  longirostrerone A 0
                  longirostrerone B 0
                  longirostrerone C 0
                  longirostrerone D 0
                  mitorubrin + 0
                  monascorubrin 0
                  purpurquinone A 0
                  purpurquinone B 0
                  purpurquinone C 0
                  rotiorinol A 0
                  rotiorinol B 0
                  rotiorinol C 0
                  rubrorotiorin 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19911
    subatomic particle 19909
      composite particle 19909
        hadron 19909
          baryon 19909
            nucleon 19909
              atomic nucleus 19909
                atom 19909
                  main group element atom 19856
                    p-block element atom 19856
                      carbon group element atom 19802
                        carbon atom 19797
                          organic molecular entity 19797
                            organic molecule 19754
                              organic cyclic compound 19562
                                organic heterocyclic compound 18899
                                  azaphilone 1
                                    (-)-rotiorin 0
                                    (7R,8R)-7,8-Dihydroxy-3,5,7-trimethyl-8H-isochromen-6-one 0
                                    12beta-hydroxychaetoviridin C 0
                                    2-thiophenecarboxylic acid [3-(4-methoxy-4-oxobutyl)-7-methyl-6,8-dioxo-2-phenyl-7-isoquinolinyl] ester 0
                                    3-(3,4-Dihydroxy-3,5-dimethylhept-1-enyl)-7,8-dihydroxy-7-methyl-8,8a-dihydro-1H-isochromen-6-one 0
                                    3-phenylpropanoic acid [3-(4-cyanophenyl)-2-cyclohexyl-7-methyl-6,8-dioxo-7-isoquinolinyl] ester 0
                                    3-phenylpropanoic acid [3-(4-cyanophenyl)-7-methyl-6,8-dioxo-2-[2-(2-pyridinyl)ethyl]-7-isoquinolinyl] ester 0
                                    4'-epichaetoviridin A 0
                                    4'-epichaetoviridin F 0
                                    5'-epichaetoviridin A 0
                                    5-Chloro-3-[(E)-3,4-dihydroxy-3,5-dimethylhept-1-enyl]-7,8-dihydroxy-7-methyl-8,8a-dihydro-1H-isochromen-6-one 0
                                    5-Chloro-3-[(E)-3,4-dihydroxy-3,5-dimethylhept-1-enyl]-7,8-dihydroxy-7-methyl-8H-isochromen-6-one 0
                                    7,8-Dihydroxy-3,7-dimethyl-6-oxo-7,8-dihydro-6H-isochromene-5-carbaldehyde 0
                                    7,8-dihydroxy-3,5,7-trimethyl-8,8a-dihydro-1H-isochromen-6-one 0
                                    Austdiol 0
                                    Berkazaphilone A 0
                                    CT2108A 0
                                    CT2108B 0
                                    Dihydrodeoxy-8-epiaustdiol 0
                                    Sclerotiorin 0
                                    [(6R,7R)-7-hydroxy-7-methyl-8-oxo-3-[(E)-prop-1-enyl]-5,6-dihydro-1H-isochromen-6-yl] 3,6-dihydroxy-4-methoxy-2-methylbenzoate 0
                                    [5-Chloranyl-3-[(1E,3E)-3,5-dimethylhepta-1,3-dienyl]-7-methyl-6,8-bis(oxidanylidene)isochromen-7-yl] ethanoate 0
                                    [7-hydroxy-7-methyl-8-oxo-3-[(E)-prop-1-enyl]-5,6-dihydro-1H-isochromen-6-yl] 2-hydroxy-4-methoxy-6-methylbenzoate 0
                                    acetic acid [5-chloro-3-(3,5-dimethylhepta-1,3-dienyl)-7-methyl-6,8-dioxo-2-benzopyran-7-yl] ester 0
                                    azanigerone A 0
                                    azanigerone B 0
                                    azanigerone C 0
                                    azanigerone D 0
                                    azanigerone E 0
                                    azanigerone F 0
                                    chaetomugilin A 0
                                    chaetomugilin D 1
                                    chaetoviridin A 0
                                    chaetoviridin C + 0
                                    chaetoviridin E 0
                                    chaetoviridin G 0
                                    chaetoviridin H 0
                                    chaetoviridin I 0
                                    chermesinone A 0
                                    chermesinone B 0
                                    chermesinone C 0
                                    comazaphilone A 0
                                    comazaphilone B 0
                                    comazaphilone C 0
                                    comazaphilone D 0
                                    comazaphilone E 0
                                    comazaphilone F 0
                                    epi-isochromophilone II 0
                                    longirostrerone A 0
                                    longirostrerone B 0
                                    longirostrerone C 0
                                    longirostrerone D 0
                                    mitorubrin + 0
                                    monascorubrin 0
                                    purpurquinone A 0
                                    purpurquinone B 0
                                    purpurquinone C 0
                                    rotiorinol A 0
                                    rotiorinol B 0
                                    rotiorinol C 0
                                    rubrorotiorin 0
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