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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:50931 term browser browse the term
Definition:An organochlorine compound that has formula C18H18ClNS.
Synonyms:exact_synonym: (3Z)-3-(2-chloro-9H-thioxanthen-9-ylidene)-N,N-dimethylpropan-1-amine
 related_synonym: (Z)-2-Chloro-9-(omega-dimethylaminopropylidene)thioxanthene;   Chlorprothixene;   Chlorprothixenum;   Clorprotixeno;   Formula=C18H18ClNS;   InChI=1S/C18H18ClNS/c1-20(2)11-5-7-14-15-6-3-4-8-17(15)21-18-10-9-13(19)12-16(14)18/h3-4,6-10,12H,5,11H2,1-2H3/b14-7-;   InChIKey=WSPOMRSOLSGNFJ-AUWJEWJLSA-N;   SMILES=[H]\\C(CCN(C)C)=C1/c2ccccc2Sc2ccc(Cl)cc12;   cis-2-Chloro-9-(3-dimethylaminopropylidene)thioxanthene
 xref: Beilstein:9208755;   CAS:113-59-7;   DrugBank:DB01239;   Drug_Central:623;   KEGG:C07953;   KEGG:D00790
 xref_mesh: MESH:D002749
 xref: Wikipedia:Chlorprothixene
 cyclic_relationship: is_enantiomer_of CHEBI:50932

show annotations for term's descendants           Sort by:
(Z)-chlorprothixene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Htr1a 5-hydroxytryptamine receptor 1A multiple interactions ISO Chlorprothixene inhibits the reaction [(2-(2',6'-dimethoxy)phenoxyethylamino)methylbenzo-1,4-dioxane binds to HTR1A protein] CTD PMID:2891550 NCBI chr 2:36,246,628...36,247,896
Ensembl chr 2:36,246,628...36,247,896
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO Chlorprothixene results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253
JBrowse link
G Prl prolactin increases secretion ISO Chlorprothixene results in increased secretion of PRL protein CTD PMID:10525070 NCBI chr17:39,814,236...39,824,299
Ensembl chr17:39,814,244...39,824,299
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19785
    role 19732
      biological role 19732
        pharmacological role 18793
          analgesic 13061
            non-narcotic analgesic 11980
              chlorprothixene 3
                (Z)-chlorprothixene 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19785
    subatomic particle 19782
      composite particle 19782
        hadron 19782
          baryon 19782
            nucleon 19782
              atomic nucleus 19782
                atom 19782
                  main group element atom 19670
                    main group molecular entity 19670
                      s-block molecular entity 19428
                        hydrogen molecular entity 19418
                          hydrides 18685
                            inorganic hydride 17409
                              pnictogen hydride 17381
                                nitrogen hydride 17223
                                  azane 16940
                                    ammonia 16939
                                      organic amino compound 16938
                                        tertiary amino compound 8629
                                          tertiary amine 616
                                            chlorprothixene 3
                                              (Z)-chlorprothixene 3
paths to the root


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