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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:50931 term browser browse the term
Definition:An organochlorine compound that has formula C18H18ClNS.
Synonyms:exact_synonym: (3Z)-3-(2-chloro-9H-thioxanthen-9-ylidene)-N,N-dimethylpropan-1-amine
 related_synonym: (Z)-2-Chloro-9-(omega-dimethylaminopropylidene)thioxanthene;   Chlorprothixene;   Chlorprothixenum;   Clorprotixeno;   Formula=C18H18ClNS;   InChI=1S/C18H18ClNS/c1-20(2)11-5-7-14-15-6-3-4-8-17(15)21-18-10-9-13(19)12-16(14)18/h3-4,6-10,12H,5,11H2,1-2H3/b14-7-;   InChIKey=WSPOMRSOLSGNFJ-AUWJEWJLSA-N;   SMILES=[H]\\C(CCN(C)C)=C1/c2ccccc2Sc2ccc(Cl)cc12;   cis-2-Chloro-9-(3-dimethylaminopropylidene)thioxanthene
 xref: Beilstein:9208755;   CAS:113-59-7;   DrugBank:DB01239;   Drug_Central:623;   KEGG:C07953;   KEGG:D00790
 xref_mesh: MESH:D002749
 xref: Wikipedia:Chlorprothixene
 cyclic_relationship: is_enantiomer_of CHEBI:50932

show annotations for term's descendants           Sort by:
(Z)-chlorprothixene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Htr1a 5-hydroxytryptamine receptor 1A multiple interactions ISO Chlorprothixene inhibits the reaction [(2-(2',6'-dimethoxy)phenoxyethylamino)methylbenzo-1,4-dioxane binds to HTR1A protein] CTD PMID:2891550 NCBI chr 2:36,694,174...36,695,442
Ensembl chr 2:36,694,174...36,695,442
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO Chlorprothixene results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008
JBrowse link
G Prl prolactin increases secretion ISO Chlorprothixene results in increased secretion of PRL protein CTD PMID:10525070 NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19821
    role 19769
      biological role 19769
        pharmacological role 18847
          analgesic 13302
            non-narcotic analgesic 12004
              chlorprothixene 3
                (Z)-chlorprothixene 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19821
    subatomic particle 19819
      composite particle 19819
        hadron 19819
          baryon 19819
            nucleon 19819
              atomic nucleus 19819
                atom 19819
                  main group element atom 19716
                    main group molecular entity 19716
                      s-block molecular entity 19502
                        hydrogen molecular entity 19498
                          hydrides 18852
                            inorganic hydride 17691
                              pnictogen hydride 17672
                                nitrogen hydride 17545
                                  azane 17279
                                    ammonia 17278
                                      organic amino compound 17278
                                        tertiary amino compound 8679
                                          tertiary amine 619
                                            chlorprothixene 3
                                              (Z)-chlorprothixene 3
paths to the root