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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:thioxanthenes
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Accession:CHEBI:50930 term browser browse the term
Definition:Thioxanthene and its substitution derivatives.


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(Z)-chlorprothixene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Htr1a 5-hydroxytryptamine receptor 1A multiple interactions ISO Chlorprothixene inhibits the reaction [(2-(2',6'-dimethoxy)phenoxyethylamino)methylbenzo-1,4-dioxane binds to HTR1A protein] CTD PMID:2891550 NCBI chr 2:36,246,628...36,247,896
Ensembl chr 2:36,246,628...36,247,896
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO Chlorprothixene results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253
JBrowse link
G Prl prolactin increases secretion ISO Chlorprothixene results in increased secretion of PRL protein CTD PMID:10525070 NCBI chr17:39,814,236...39,824,299
Ensembl chr17:39,814,244...39,824,299
JBrowse link
2-[4-[3-[2-(trifluoromethyl)-9-thioxanthenylidene]propyl]-1-piperazinyl]ethanol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A decreases activity
multiple interactions
ISO Flupenthixol analog results in decreased activity of ABCB1 protein; Flupenthixol analog results in decreased activity of ABCB1 protein mutant form
Flupenthixol analog inhibits the reaction [ABCB1 protein results in decreased susceptibility to Doxorubicin]; Flupenthixol analog inhibits the reaction [ABCB1 protein results in decreased susceptibility to Vincristine]
CTD PMID:7905786, PMID:12711602 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Drd1 dopamine receptor D1 affects binding ISO Flupenthixol binds to DRD1 protein CTD PMID:1352677 NCBI chr17:11,099,736...11,104,352
Ensembl chr17:11,101,306...11,103,541
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO Flupenthixol results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 decreases expression ISO Flupenthixol results in decreased expression of PTGS1 protein CTD PMID:8897462 NCBI chr 3:15,560,685...15,582,339
Ensembl chr 3:15,560,712...15,582,344
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression ISO Flupenthixol results in decreased expression of PTGS2 protein CTD PMID:8897462 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
chlorprothixene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Htr1a 5-hydroxytryptamine receptor 1A multiple interactions ISO Chlorprothixene inhibits the reaction [(2-(2',6'-dimethoxy)phenoxyethylamino)methylbenzo-1,4-dioxane binds to HTR1A protein] CTD PMID:2891550 NCBI chr 2:36,246,628...36,247,896
Ensembl chr 2:36,246,628...36,247,896
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO Chlorprothixene results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253
JBrowse link
G Prl prolactin increases secretion ISO Chlorprothixene results in increased secretion of PRL protein CTD PMID:10525070 NCBI chr17:39,814,236...39,824,299
Ensembl chr17:39,814,244...39,824,299
JBrowse link
clopenthixol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO Clopenthixol results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253
JBrowse link
flupenthixol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions
decreases activity
ISO Flupenthixol analog inhibits the reaction [ABCB1 protein results in decreased susceptibility to Doxorubicin]; Flupenthixol analog inhibits the reaction [ABCB1 protein results in decreased susceptibility to Vincristine]
Flupenthixol analog results in decreased activity of ABCB1 protein; Flupenthixol analog results in decreased activity of ABCB1 protein mutant form
CTD PMID:7905786, PMID:12711602 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Drd1 dopamine receptor D1 affects binding ISO Flupenthixol binds to DRD1 protein CTD PMID:1352677 NCBI chr17:11,099,736...11,104,352
Ensembl chr17:11,101,306...11,103,541
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO Flupenthixol results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 decreases expression ISO Flupenthixol results in decreased expression of PTGS1 protein CTD PMID:8897462 NCBI chr 3:15,560,685...15,582,339
Ensembl chr 3:15,560,712...15,582,344
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression ISO Flupenthixol results in decreased expression of PTGS2 protein CTD PMID:8897462 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
hycanthone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity ISO Hycanthone results in increased activity of NR1I2 protein CTD PMID:25455453 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
lucanthone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca12 ATP binding cassette subfamily A member 12 increases expression ISO Lucanthone results in increased expression of ABCA12 mRNA CTD PMID:21148553 NCBI chr 9:78,521,477...78,693,421
Ensembl chr 9:78,522,464...78,693,028
JBrowse link
G Acta2 actin alpha 2, smooth muscle increases expression ISO Lucanthone results in increased expression of ACTA2 mRNA CTD PMID:21148553 NCBI chr 1:252,537,614...252,550,394
Ensembl chr 1:252,537,615...252,550,394
JBrowse link
G Aldh1l2 aldehyde dehydrogenase 1 family, member L2 decreases expression ISO Lucanthone results in decreased expression of ALDH1L2 mRNA CTD PMID:21148553 NCBI chr 7:26,375,866...26,425,838
Ensembl chr 7:26,375,866...26,425,108
JBrowse link
G Anln anillin, actin binding protein decreases expression ISO Lucanthone results in decreased expression of ANLN mRNA CTD PMID:21148553 NCBI chr 8:23,336,455...23,397,122
Ensembl chr 8:23,337,621...23,390,773
JBrowse link
G Anxa3 annexin A3 decreases expression ISO Lucanthone results in decreased expression of ANXA3 mRNA CTD PMID:21148553 NCBI chr14:14,371,921...14,426,503
Ensembl chr14:14,364,008...14,426,437
JBrowse link
G Aqp3 aquaporin 3 (Gill blood group) increases expression ISO Lucanthone results in increased expression of AQP3 mRNA CTD PMID:21148553 NCBI chr 5:57,423,735...57,429,252
Ensembl chr 5:57,423,734...57,429,245
JBrowse link
G Arhgap11a Rho GTPase activating protein 11A decreases expression ISO Lucanthone results in decreased expression of ARHGAP11A mRNA CTD PMID:21148553 NCBI chr 3:105,281,827...105,298,108
Ensembl chr 3:105,281,827...105,298,108
JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) decreases expression ISO Lucanthone results in decreased expression of ASNS mRNA CTD PMID:21148553 NCBI chr 4:33,742,876...33,761,106
Ensembl chr 4:33,743,364...33,761,163
JBrowse link
G Aspm assembly factor for spindle microtubules decreases expression ISO Lucanthone results in decreased expression of ASPM mRNA CTD PMID:21148553 NCBI chr13:56,546,021...56,591,793
Ensembl chr13:56,546,021...56,591,793
JBrowse link
G Atad2 ATPase family, AAA domain containing 2 decreases expression ISO Lucanthone results in decreased expression of ATAD2 mRNA CTD PMID:21148553 NCBI chr 7:97,984,754...98,027,379
Ensembl chr 7:97,984,862...98,026,052
JBrowse link
G Aurka aurora kinase A decreases expression ISO Lucanthone results in decreased expression of AURKA mRNA CTD PMID:21148553 NCBI chr 3:170,364,177...170,380,278
Ensembl chr 3:170,364,181...170,378,210
JBrowse link
G Aurkb aurora kinase B decreases expression ISO Lucanthone results in decreased expression of AURKB mRNA CTD PMID:21148553 NCBI chr10:55,625,860...55,632,399
Ensembl chr10:55,626,741...55,634,991
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases expression ISO Lucanthone results in decreased expression of BIRC5 mRNA CTD PMID:21148553 NCBI chr10:106,856,097...106,864,419
Ensembl chr10:106,856,097...106,864,413
JBrowse link
G Blm BLM RecQ like helicase decreases expression ISO Lucanthone results in decreased expression of BLM mRNA CTD PMID:21148553 NCBI chr 1:142,246,773...142,332,616
Ensembl chr 1:142,246,790...142,332,588
JBrowse link
G Brca1 BRCA1, DNA repair associated decreases expression ISO Lucanthone results in decreased expression of BRCA1 mRNA CTD PMID:21148553 NCBI chr10:89,394,821...89,455,093
Ensembl chr10:89,394,803...89,454,681
JBrowse link
G Brca2 BRCA2, DNA repair associated decreases expression ISO Lucanthone results in decreased expression of BRCA2 mRNA CTD PMID:21148553 NCBI chr12:503,660...544,754
Ensembl chr12:504,007...544,748
JBrowse link
G Bub1 BUB1 mitotic checkpoint serine/threonine kinase decreases expression ISO Lucanthone results in decreased expression of BUB1 mRNA CTD PMID:21148553 NCBI chr 3:120,373,604...120,404,910
Ensembl chr 3:120,373,604...120,404,910
JBrowse link
G Bub1b BUB1 mitotic checkpoint serine/threonine kinase B decreases expression ISO Lucanthone results in decreased expression of BUB1B mRNA CTD PMID:21148553 NCBI chr 3:110,367,949...110,420,471
Ensembl chr 3:110,367,939...110,420,458
JBrowse link
G Ccn3 cellular communication network factor 3 increases expression ISO Lucanthone results in increased expression of CCN3 mRNA CTD PMID:21148553 NCBI chr 7:94,375,134...94,382,154
Ensembl chr 7:94,375,020...94,383,024
JBrowse link
G Ccna2 cyclin A2 decreases expression ISO Lucanthone results in decreased expression of CCNA2 mRNA CTD PMID:21148553 NCBI chr 2:123,274,727...123,282,266
Ensembl chr 2:123,275,881...123,282,214
JBrowse link
G Ccnb1 cyclin B1 decreases expression ISO Lucanthone results in decreased expression of CCNB1 mRNA CTD PMID:21148553 NCBI chr 2:30,782,133...30,791,106
Ensembl chr 2:30,783,915...30,791,221
JBrowse link
G Ccnb2 cyclin B2 decreases expression ISO Lucanthone results in decreased expression of CCNB2 mRNA CTD PMID:21148553 NCBI chr 8:76,847,972...76,861,165 JBrowse link
G Cdc20 cell division cycle 20 decreases expression ISO Lucanthone results in decreased expression of CDC20 mRNA CTD PMID:21148553 NCBI chr 5:137,260,728...137,264,931
Ensembl chr 5:137,260,739...137,265,015
JBrowse link
G Cdc25c cell division cycle 25C decreases expression ISO Lucanthone results in decreased expression of CDC25C mRNA CTD PMID:21148553 NCBI chr18:27,528,768...27,550,316
Ensembl chr18:27,528,354...27,550,224
JBrowse link
G Cdc45 cell division cycle 45 decreases expression ISO Lucanthone results in decreased expression of CDC45 mRNA CTD PMID:21148553 NCBI chr11:86,328,785...86,354,099
Ensembl chr11:86,329,012...86,358,453
JBrowse link
G Cdc6 cell division cycle 6 decreases expression ISO Lucanthone results in decreased expression of CDC6 mRNA CTD PMID:21148553 NCBI chr10:86,819,477...86,833,301
Ensembl chr10:86,819,472...86,833,402
JBrowse link
G Cdca2 cell division cycle associated 2 decreases expression ISO Lucanthone results in decreased expression of CDCA2 mRNA CTD PMID:21148553 NCBI chr15:44,365,396...44,411,601
Ensembl chr15:44,365,405...44,411,004
JBrowse link
G Cdk1 cyclin-dependent kinase 1 decreases expression ISO Lucanthone results in decreased expression of CDK1 mRNA CTD PMID:21148553 NCBI chr20:20,576,341...20,591,510
Ensembl chr20:20,576,377...20,591,549
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO Lucanthone results in increased expression of CDKN1A mRNA CTD PMID:21148553 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn3 cyclin-dependent kinase inhibitor 3 decreases expression ISO Lucanthone results in decreased expression of CDKN3 mRNA CTD PMID:21148553 NCBI chr15:23,553,171...23,564,538
Ensembl chr15:23,553,128...23,564,535
JBrowse link
G Cenpa centromere protein A decreases expression ISO Lucanthone results in decreased expression of CENPA mRNA CTD PMID:21148553 NCBI chr 6:27,072,259...27,080,863
Ensembl chr 6:27,072,166...27,080,856
JBrowse link
G Cenpe centromere protein E decreases expression ISO Lucanthone results in decreased expression of CENPE mRNA CTD PMID:21148553 NCBI chr 2:240,395,974...240,454,785
Ensembl chr 2:240,396,152...240,454,747
JBrowse link
G Cenpf centromere protein F decreases expression ISO Lucanthone results in decreased expression of CENPF mRNA CTD PMID:21148553 NCBI chr13:108,132,499...108,178,609
Ensembl chr13:108,132,499...108,178,609
JBrowse link
G Cenpi centromere protein I decreases expression ISO Lucanthone results in decreased expression of CENPI mRNA CTD PMID:21148553 NCBI chr  X:105,147,045...105,198,798
Ensembl chr  X:105,147,153...105,198,797
JBrowse link
G Cenpk centromere protein K decreases expression ISO Lucanthone results in decreased expression of CENPK mRNA CTD PMID:21148553 NCBI chr 2:34,312,766...34,373,945
Ensembl chr 2:34,312,766...34,335,776
JBrowse link
G Cenpl centromere protein L decreases expression ISO Lucanthone results in decreased expression of CENPL mRNA CTD PMID:21148553 NCBI chr13:78,886,092...78,901,025
Ensembl chr13:78,886,163...78,901,420
JBrowse link
G Cenpu centromere protein U decreases expression ISO Lucanthone results in decreased expression of CENPU mRNA CTD PMID:21148553 NCBI chr16:48,898,032...48,921,248
Ensembl chr16:48,897,982...48,921,242
JBrowse link
G Cep55 centrosomal protein 55 decreases expression ISO Lucanthone results in decreased expression of CEP55 mRNA CTD PMID:21148553 NCBI chr 1:256,745,251...256,760,794
Ensembl chr 1:256,745,288...256,760,796
JBrowse link
G Cip2a cellular inhibitor of PP2A decreases expression ISO Lucanthone results in decreased expression of CIP2A mRNA CTD PMID:21148553 NCBI chr11:54,373,794...54,404,704
Ensembl chr11:54,377,374...54,404,612
JBrowse link
G Cit citron rho-interacting serine/threonine kinase decreases expression ISO Lucanthone results in decreased expression of CIT mRNA CTD PMID:21148553 NCBI chr12:46,334,669...46,494,152
Ensembl chr12:46,334,665...46,494,174
JBrowse link
G Ckap2l cytoskeleton associated protein 2-like decreases expression ISO Lucanthone results in decreased expression of CKAP2L mRNA CTD PMID:21148553 NCBI chr 3:121,796,221...121,822,352
Ensembl chr 3:121,796,238...121,822,436
JBrowse link
G Cks1b CDC28 protein kinase regulatory subunit 1B decreases expression ISO Lucanthone results in decreased expression of CKS1B mRNA CTD PMID:21148553 NCBI chr 2:188,740,564...188,745,144
Ensembl chr 2:188,740,573...188,745,144
JBrowse link
G Clca2 chloride channel accessory 2 increases expression ISO Lucanthone results in increased expression of CLCA2 mRNA CTD PMID:21148553 NCBI chr 2:250,954,423...250,981,544
Ensembl chr 2:250,954,397...250,981,623
JBrowse link
G Cldn1 claudin 1 decreases expression ISO Lucanthone results in decreased expression of CLDN1 mRNA CTD PMID:21148553 NCBI chr11:77,815,216...77,830,373
Ensembl chr11:77,815,181...77,830,416
JBrowse link
G Clgn calmegin decreases expression ISO Lucanthone results in decreased expression of CLGN mRNA CTD PMID:21148553 NCBI chr19:24,545,257...24,578,527
Ensembl chr19:24,545,318...24,576,798
JBrowse link
G Ctsd cathepsin D increases expression ISO Lucanthone results in increased expression of CTSD mRNA; Lucanthone results in increased expression of CTSD protein CTD PMID:21148553 NCBI chr 1:215,541,570...215,553,446
Ensembl chr 1:215,541,542...215,553,451
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 increases expression ISO Lucanthone results in increased expression of CXCL10 mRNA CTD PMID:21148553 NCBI chr14:17,210,733...17,212,930
Ensembl chr14:17,210,733...17,212,930
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression ISO Lucanthone results in increased expression of CYP1A1 mRNA CTD PMID:21148553 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 decreases expression ISO Lucanthone results in decreased expression of DDIT3 mRNA CTD PMID:21148553 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Depdc1 DEP domain containing 1 decreases expression ISO Lucanthone results in decreased expression of DEPDC1 mRNA CTD PMID:21148553 NCBI chr 2:264,704,738...264,738,265
Ensembl chr 2:264,704,769...264,738,257
JBrowse link
G Depdc1b DEP domain containing 1B decreases expression ISO Lucanthone results in decreased expression of DEPDC1B mRNA CTD PMID:21148553 NCBI chr 2:39,980,796...40,069,982
Ensembl chr 2:40,000,313...40,069,975
JBrowse link
G Dhcr24 24-dehydrocholesterol reductase increases expression ISO Lucanthone results in increased expression of DHCR24 mRNA CTD PMID:21148553 NCBI chr 5:126,164,708...126,188,926
Ensembl chr 5:126,164,674...126,191,206
JBrowse link
G Diaph3 diaphanous-related formin 3 decreases expression ISO Lucanthone results in decreased expression of DIAPH3 mRNA CTD PMID:21148553 NCBI chr15:69,928,507...70,400,077
Ensembl chr15:70,039,424...70,399,924
JBrowse link
G Dlgap5 DLG associated protein 5 decreases expression ISO Lucanthone results in decreased expression of DLGAP5 mRNA CTD PMID:21148553 NCBI chr15:24,167,484...24,199,417
Ensembl chr15:24,167,486...24,199,341
JBrowse link
G Dnai3 dynein axonemal intermediate chain 3 increases expression ISO Lucanthone results in increased expression of DNAI3 mRNA CTD PMID:21148553 NCBI chr 2:251,912,432...251,970,699
Ensembl chr 2:251,912,368...251,970,768
JBrowse link
G Dpp4 dipeptidylpeptidase 4 increases expression ISO Lucanthone results in increased expression of DPP4 mRNA CTD PMID:21148553 NCBI chr 3:48,291,055...48,372,672
Ensembl chr 3:48,291,055...48,372,672
JBrowse link
G Dtl denticleless E3 ubiquitin protein ligase homolog decreases expression ISO Lucanthone results in decreased expression of DTL mRNA CTD PMID:21148553 NCBI chr13:110,219,276...110,257,345
Ensembl chr13:110,220,283...110,257,367
JBrowse link
G Ect2 epithelial cell transforming 2 decreases expression ISO Lucanthone results in decreased expression of ECT2 mRNA CTD PMID:21148553 NCBI chr 2:112,769,385...112,831,476
Ensembl chr 2:112,769,385...112,831,476
JBrowse link
G Efemp1 EGF containing fibulin extracellular matrix protein 1 decreases expression ISO Lucanthone results in decreased expression of EFEMP1 mRNA CTD PMID:21148553 NCBI chr14:113,202,382...113,294,993
Ensembl chr14:113,202,419...113,295,014
JBrowse link
G Ercc6l ERCC excision repair 6 like, spindle assembly checkpoint helicase decreases expression ISO Lucanthone results in decreased expression of ERCC6L mRNA CTD PMID:21148553 NCBI chr  X:72,018,373...72,034,140
Ensembl chr  X:72,018,373...72,034,099
JBrowse link
G Esco2 establishment of sister chromatid cohesion N-acetyltransferase 2 decreases expression ISO Lucanthone results in decreased expression of ESCO2 mRNA CTD PMID:21148553 NCBI chr15:42,500,929...42,519,019
Ensembl chr15:42,500,929...42,518,855
JBrowse link
G Espl1 extra spindle pole bodies like 1, separase decreases expression ISO Lucanthone results in decreased expression of ESPL1 mRNA CTD PMID:21148553 NCBI chr 7:143,896,890...143,923,868
Ensembl chr 7:143,897,014...143,923,868
JBrowse link
G Exo1 exonuclease 1 decreases expression ISO Lucanthone results in decreased expression of EXO1 mRNA CTD PMID:21148553 NCBI chr13:93,936,989...93,962,749
Ensembl chr13:93,939,022...93,960,342
JBrowse link
G Exosc8 exosome component 8 decreases expression ISO Lucanthone results in decreased expression of EXOSC8 mRNA CTD PMID:21148553 NCBI chr 2:143,925,643...143,932,240
Ensembl chr 2:143,925,546...143,931,940
JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit decreases expression ISO Lucanthone results in decreased expression of EZH2 mRNA CTD PMID:21148553 NCBI chr 4:77,284,404...77,347,011
Ensembl chr 4:77,284,404...77,347,011
JBrowse link
G Fam72a family with sequence similarity 72, member A decreases expression ISO Lucanthone results in decreased expression of FAM72A mRNA CTD PMID:21148553 NCBI chr13:48,288,071...48,298,604
Ensembl chr13:48,287,873...48,298,664
JBrowse link
G Fanci FA complementation group I decreases expression ISO Lucanthone results in decreased expression of FANCI mRNA CTD PMID:21148553 NCBI chr 1:141,116,565...141,172,997
Ensembl chr 1:141,120,166...141,172,483
JBrowse link
G Fbxo5 F-box protein 5 decreases expression ISO Lucanthone results in decreased expression of FBXO5 mRNA CTD PMID:21148553 NCBI chr 1:42,461,277...42,467,646
Ensembl chr 1:42,461,291...42,467,586
JBrowse link
G Flg filaggrin decreases expression ISO Lucanthone results in decreased expression of FLG mRNA CTD PMID:21148553 NCBI chr 2:193,565,401...193,574,297 JBrowse link
G Foxm1 forkhead box M1 decreases expression ISO Lucanthone results in decreased expression of FOXM1 mRNA CTD PMID:21148553 NCBI chr 4:161,685,236...161,697,633
Ensembl chr 4:161,685,258...161,696,305
JBrowse link
G Gbp1 guanylate binding protein 1 decreases expression ISO Lucanthone results in decreased expression of GBP1 mRNA CTD PMID:21148553 NCBI chr 2:248,343,334...248,423,402
Ensembl chr 2:248,398,917...248,409,570
JBrowse link
G Gdf15 growth differentiation factor 15 increases expression ISO Lucanthone results in increased expression of GDF15 mRNA CTD PMID:21148553 NCBI chr16:20,555,395...20,557,978
Ensembl chr16:20,555,395...20,557,978
JBrowse link
G Gpnmb glycoprotein nmb increases expression ISO Lucanthone results in increased expression of GPNMB mRNA CTD PMID:21148553 NCBI chr 4:78,694,447...78,715,685
Ensembl chr 4:78,694,447...78,715,683
JBrowse link
G Gpr1 G protein-coupled receptor 1 decreases expression ISO Lucanthone results in decreased expression of GPR1 mRNA CTD PMID:21148553 NCBI chr 9:69,958,607...69,991,410
Ensembl chr 9:69,959,025...69,960,086
JBrowse link
G Gpx8 glutathione peroxidase 8 decreases expression ISO Lucanthone results in decreased expression of GPX8 mRNA CTD PMID:21148553 NCBI chr 2:44,903,337...44,907,046
Ensembl chr 2:44,903,337...44,907,030
JBrowse link
G Gtpbp2 GTP binding protein 2 decreases expression ISO Lucanthone results in decreased expression of GTPBP2 mRNA CTD PMID:21148553 NCBI chr 9:17,198,957...17,208,456
Ensembl chr 9:17,198,957...17,209,220
JBrowse link
G H1f4 H1.4 linker histone, cluster member decreases expression ISO Lucanthone results in decreased expression of H1-4 mRNA CTD PMID:21148553 NCBI chr17:43,734,461...43,735,120
Ensembl chr17:43,734,461...43,735,120
JBrowse link
G H1f5 H1.5 linker histone, cluster member decreases expression ISO Lucanthone results in decreased expression of H1-5 mRNA CTD PMID:21148553 NCBI chr17:44,766,313...44,766,981
Ensembl chr17:44,766,313...44,766,981
JBrowse link
G H2ac12 H2A clustered histone 12 decreases expression ISO Lucanthone results in decreased expression of H2AC12 mRNA CTD PMID:21148553 NCBI chr17:44,527,990...44,528,557
Ensembl chr17:44,528,125...44,528,511
JBrowse link
G H2ac21 H2A clustered histone 21 decreases expression ISO Lucanthone results in decreased expression of H2AC21 mRNA CTD PMID:21148553 NCBI chr 2:198,359,754...198,360,146
Ensembl chr 2:198,359,754...198,360,146
JBrowse link
G H2bc9 H2B clustered histone 9 decreases expression ISO Lucanthone results in decreased expression of H2BC9 mRNA CTD PMID:21148553 NCBI chr17:44,519,815...44,520,269
Ensembl chr17:44,519,860...44,520,240
JBrowse link
G H3c13 H3 clustered histone 13 decreases expression ISO Lucanthone results in decreased expression of H3C13 mRNA CTD PMID:21148553 NCBI chr17:43,776,018...43,776,779
Ensembl chr17:43,791,657...43,792,067
Ensembl chr17:43,791,657...43,792,067
Ensembl chr17:43,791,657...43,792,067
Ensembl chr 2:43,791,657...43,792,067
Ensembl chr17:43,791,657...43,792,067
Ensembl chr17:43,791,657...43,792,067
Ensembl chr 2:43,791,657...43,792,067
Ensembl chr 2:43,791,657...43,792,067
JBrowse link
G H4f3 H1.3 linker histone, cluster member decreases expression ISO Lucanthone results in decreased expression of H1-3 mRNA CTD PMID:21148553 NCBI chr17:43,797,711...43,798,450
Ensembl chr17:43,797,721...43,798,383
JBrowse link
G Hist1h2ail1 histone cluster 1 H2a family member I like 1 decreases expression ISO Lucanthone results in decreased expression of H3C4 mRNA CTD PMID:21148553 NCBI chr17:43,814,773...43,815,183
Ensembl chr17:43,814,773...43,815,183
Ensembl chr17:43,814,773...43,815,183
JBrowse link
G Hist1h2ak histone cluster 1, H2ak decreases expression ISO Lucanthone results in decreased expression of H2AC4 mRNA CTD PMID:21148553 NCBI chr17:44,840,990...44,841,382
Ensembl chr17:44,840,990...44,841,382
JBrowse link
G Hist1h2bl histone cluster 1 H2B family member l decreases expression ISO Lucanthone results in decreased expression of H2BC8 mRNA CTD PMID:21148553 NCBI chr17:44,748,445...44,748,910
Ensembl chr17:44,748,482...44,748,862
JBrowse link
G Hist1h2bq histone cluster 1 H2B family member Q decreases expression ISO Lucanthone results in decreased expression of H2BC7 mRNA CTD PMID:21148553 NCBI chr17:43,679,925...43,689,311
Ensembl chr17:43,679,925...43,689,311
JBrowse link
G Hist1h3b histone cluster 1, H3b decreases expression ISO Lucanthone results in decreased expression of H3C12 mRNA CTD PMID:21148553 NCBI chr17:44,760,023...44,764,058
Ensembl chr17:44,839,721...44,840,131
Ensembl chr17:44,839,721...44,840,131
Ensembl chr17:44,839,721...44,840,131
Ensembl chr17:44,839,721...44,840,131
JBrowse link
G Hist2h4 histone cluster 2, H4 decreases expression ISO Lucanthone results in decreased expression of H4C2 mRNA CTD PMID:21148553 NCBI chr 2:198,411,955...198,412,350
Ensembl chr 2:198,411,955...198,412,350
JBrowse link
G Hist2h4a histone cluster 2 H4 family member A decreases expression ISO Lucanthone results in decreased expression of H4C4 mRNA CTD PMID:21148553 NCBI chr 4:170,800,539...170,800,979
Ensembl chr17:43,770,250...43,770,561
Ensembl chr17:43,770,250...43,770,561
Ensembl chr17:43,770,250...43,770,561
Ensembl chr17:43,770,250...43,770,561
Ensembl chr 2:43,770,250...43,770,561
Ensembl chr17:43,770,250...43,770,561
Ensembl chr17:43,770,250...43,770,561
Ensembl chr17:43,770,250...43,770,561
Ensembl chr 4:43,770,250...43,770,561
Ensembl chr 4:43,770,250...43,770,561
Ensembl chr 4:43,770,250...43,770,561
Ensembl chr 4:43,770,250...43,770,561
JBrowse link
G Hjurp Holliday junction recognition protein decreases expression ISO Lucanthone results in decreased expression of HJURP mRNA CTD PMID:21148553 NCBI chr 9:95,347,739...95,362,228
Ensembl chr 9:95,349,086...95,362,014
JBrowse link
G Hmgb2 high mobility group box 2 decreases expression ISO Lucanthone results in decreased expression of HMGB2 mRNA CTD PMID:21148553 NCBI chr16:36,077,615...36,080,191
Ensembl chr16:36,077,617...36,080,191
Ensembl chr11:36,077,617...36,080,191
JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 increases expression ISO Lucanthone results in increased expression of HMGCS1 mRNA CTD PMID:21148553 NCBI chr 2:52,427,351...52,445,082
Ensembl chr 2:52,431,601...52,445,055
JBrowse link
G Hmmr hyaluronan-mediated motility receptor decreases expression ISO Lucanthone results in decreased expression of HMMR mRNA CTD PMID:21148553 NCBI chr10:25,861,490...25,890,639
Ensembl chr10:25,861,490...25,890,639
JBrowse link
G Icam1 intercellular adhesion molecule 1 increases expression ISO Lucanthone results in increased expression of ICAM1 mRNA CTD PMID:21148553 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Idi1 isopentenyl-diphosphate delta isomerase 1 increases expression ISO Lucanthone results in increased expression of IDI1 mRNA CTD PMID:21148553 NCBI chr17:57,976,266...57,984,036
Ensembl chr17:57,976,268...57,984,036
JBrowse link
G Ifi30 IFI30, lysosomal thiol reductase increases expression ISO Lucanthone results in increased expression of IFI30 mRNA CTD PMID:21148553 NCBI chr16:20,426,566...20,430,772
Ensembl chr16:20,426,566...20,430,752
JBrowse link
G Il18 interleukin 18 decreases expression ISO Lucanthone results in decreased expression of IL18 mRNA CTD PMID:21148553 NCBI chr 8:55,009,666...55,016,286
Ensembl chr 8:54,993,859...55,016,299
JBrowse link
G Il24 interleukin 24 increases expression ISO Lucanthone results in increased expression of IL24 mRNA CTD PMID:21148553 NCBI chr13:47,618,451...47,623,849
Ensembl chr13:47,618,452...47,623,849
JBrowse link
G Il6 interleukin 6 increases expression ISO Lucanthone results in increased expression of IL6 mRNA CTD PMID:21148553 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Iqgap3 IQ motif containing GTPase activating protein 3 decreases expression ISO Lucanthone results in decreased expression of IQGAP3 mRNA CTD PMID:21148553 NCBI chr 2:187,447,477...187,489,630
Ensembl chr 2:187,447,501...187,489,630
JBrowse link
G Itga3 integrin subunit alpha 3 increases expression ISO Lucanthone results in increased expression of ITGA3 mRNA CTD PMID:21148553 NCBI chr10:82,855,841...82,887,755
Ensembl chr10:82,855,613...82,887,497
JBrowse link
G Kif11 kinesin family member 11 decreases expression ISO Lucanthone results in decreased expression of KIF11 mRNA CTD PMID:21148553 NCBI chr 1:256,035,866...256,088,299
Ensembl chr 1:256,035,866...256,088,299
JBrowse link
G Kif14 kinesin family member 14 decreases expression ISO Lucanthone results in decreased expression of KIF14 mRNA CTD PMID:21148553 NCBI chr13:53,350,073...53,421,992
Ensembl chr13:53,351,717...53,420,111
JBrowse link
G Kif15 kinesin family member 15 decreases expression ISO Lucanthone results in decreased expression of KIF15 mRNA CTD PMID:21148553 NCBI chr 8:132,033,117...132,103,528
Ensembl chr 8:132,032,944...132,103,927
JBrowse link
G Kif20a kinesin family member 20A decreases expression ISO Lucanthone results in decreased expression of KIF20A mRNA CTD PMID:21148553 NCBI chr18:27,424,328...27,432,814
Ensembl chr18:27,424,328...27,432,814
JBrowse link
G Kif20b kinesin family member 20B decreases expression ISO Lucanthone results in decreased expression of KIF20B mRNA CTD PMID:21148553 NCBI chr 1:253,220,038...253,275,523
Ensembl chr 1:253,221,812...253,275,490
JBrowse link
G Kif22 kinesin family member 22 decreases expression ISO Lucanthone results in decreased expression of KIF22 mRNA CTD PMID:21148553 NCBI chr 1:198,461,406...198,476,430
Ensembl chr 1:198,461,169...198,476,476
JBrowse link
G Kif23 kinesin family member 23 decreases expression ISO Lucanthone results in decreased expression of KIF23 mRNA CTD PMID:21148553 NCBI chr 8:66,866,043...66,893,241
Ensembl chr 8:66,866,082...66,893,196
JBrowse link
G Kif2c kinesin family member 2C decreases expression ISO Lucanthone results in decreased expression of KIF2C mRNA CTD PMID:21148553 NCBI chr 5:136,027,923...136,053,268
Ensembl chr 5:136,027,934...136,053,210
JBrowse link
G Kif4a kinesin family member 4A decreases expression ISO Lucanthone results in decreased expression of KIF4A mRNA CTD PMID:21148553 NCBI chr  X:70,461,700...70,561,084
Ensembl chr  X:70,461,718...70,561,189
JBrowse link
G Kifc1 kinesin family member C1 decreases expression ISO Lucanthone results in decreased expression of KIFC1 mRNA CTD PMID:21148553 NCBI chr20:5,509,059...5,526,175
Ensembl chr20:5,509,059...5,526,175
JBrowse link
G Lamp3 lysosomal-associated membrane protein 3 decreases expression ISO Lucanthone results in decreased expression of LAMP3 mRNA CTD PMID:21148553 NCBI chr11:84,930,965...85,000,694
Ensembl chr11:84,972,132...85,000,681
JBrowse link
G Lin9 lin-9 DREAM MuvB core complex component decreases expression ISO Lucanthone results in decreased expression of LIN9 mRNA CTD PMID:21148553 NCBI chr13:98,924,728...98,969,051
Ensembl chr13:98,924,962...98,967,735
JBrowse link
G LOC100911204 protein CASC5-like decreases expression ISO Lucanthone results in decreased expression of KNL1 mRNA CTD PMID:21148553 NCBI chr 3:112,531,429...112,560,698
Ensembl chr 3:112,531,703...112,560,634
JBrowse link
G LOC102551184 histone H4-like decreases expression ISO Lucanthone results in decreased expression of H4C12 mRNA CTD PMID:21148553 NCBI chr17:43,770,198...43,821,579 JBrowse link
G LOC690126 hypothetical protein LOC690126 decreases expression ISO Lucanthone results in decreased expression of H3C15 mRNA CTD PMID:21148553 NCBI chr 2:198,379,864...198,381,026
Ensembl chr 2:198,380,426...198,380,836
JBrowse link
G Lrp1 LDL receptor related protein 1 increases expression ISO Lucanthone results in increased expression of LRP1 mRNA CTD PMID:21148553 NCBI chr 7:70,846,313...70,927,028
Ensembl chr 7:70,846,344...70,926,903
JBrowse link
G Lxn latexin increases expression ISO Lucanthone results in increased expression of LXN mRNA CTD PMID:21148553 NCBI chr 2:164,628,565...164,634,434
Ensembl chr 2:164,628,566...164,634,434
JBrowse link
G Mad2l1 mitotic arrest deficient 2 like 1 decreases expression ISO Lucanthone results in decreased expression of MAD2L1 mRNA CTD PMID:21148553 NCBI chr 4:97,530,993...97,543,179
Ensembl chr 4:97,531,083...97,537,086
JBrowse link
G Mboat1 membrane bound O-acyltransferase domain containing 1 decreases expression ISO Lucanthone results in decreased expression of MBOAT1 mRNA CTD PMID:21148553 NCBI chr17:36,061,775...36,177,457
Ensembl chr17:36,061,775...36,177,457
JBrowse link
G Mcm10 minichromosome maintenance 10 replication initiation factor decreases expression ISO Lucanthone results in decreased expression of MCM10 mRNA CTD PMID:21148553 NCBI chr17:77,224,218...77,245,486
Ensembl chr17:77,224,112...77,246,478
JBrowse link
G Mcm8 minichromosome maintenance 8 homologous recombination repair factor decreases expression ISO Lucanthone results in decreased expression of MCM8 mRNA CTD PMID:21148553 NCBI chr 3:125,470,499...125,500,795
Ensembl chr 3:125,470,551...125,500,795
JBrowse link
G Melk maternal embryonic leucine zipper kinase decreases expression ISO Lucanthone results in decreased expression of MELK mRNA CTD PMID:21148553 NCBI chr 5:59,783,835...59,844,356
Ensembl chr 5:59,783,890...59,844,356
JBrowse link
G Mki67 marker of proliferation Ki-67 decreases expression ISO Lucanthone results in decreased expression of MKI67 mRNA CTD PMID:21148553 NCBI chr 1:207,993,895...208,020,454
Ensembl chr 1:207,993,895...208,020,454
JBrowse link
G Mmp1 matrix metallopeptidase 1 increases expression ISO Lucanthone results in increased expression of MMP1 mRNA CTD PMID:21148553 NCBI chr 8:5,703,206...5,723,593
Ensembl chr 8:5,703,206...5,723,591
JBrowse link
G Mnd1 meiotic nuclear divisions 1 decreases expression ISO Lucanthone results in decreased expression of MND1 mRNA CTD PMID:21148553 NCBI chr 2:183,073,029...183,140,768
Ensembl chr 2:183,073,187...183,128,932
JBrowse link
G Mocos molybdenum cofactor sulfurase decreases expression ISO Lucanthone results in decreased expression of MOCOS mRNA CTD PMID:21148553 NCBI chr18:16,590,086...16,636,312
Ensembl chr18:16,590,197...16,636,084
JBrowse link
G Msmo1 methylsterol monooxygenase 1 increases expression ISO Lucanthone results in increased expression of MSMO1 mRNA CTD PMID:21148553 NCBI chr16:26,859,441...26,875,880
Ensembl chr16:26,859,397...26,875,973
JBrowse link
G Mtfr2 mitochondrial fission regulator 2 decreases expression ISO Lucanthone results in decreased expression of MTFR2 mRNA CTD PMID:21148553 NCBI chr 1:15,834,779...15,850,424
Ensembl chr 1:15,782,477...15,860,624
JBrowse link
G Mx2 MX dynamin like GTPase 2 increases expression ISO Lucanthone results in increased expression of MX1 mRNA CTD PMID:21148553 NCBI chr11:38,035,306...38,066,185
Ensembl chr11:38,035,450...38,059,950
JBrowse link
G Mybl2 MYB proto-oncogene like 2 decreases expression ISO Lucanthone results in decreased expression of MYBL2 mRNA CTD PMID:21148553 NCBI chr 3:159,421,638...159,450,087
Ensembl chr 3:159,421,671...159,450,086
JBrowse link
G Ncapg non-SMC condensin I complex, subunit G decreases expression ISO Lucanthone results in decreased expression of NCAPG mRNA CTD PMID:21148553 NCBI chr14:69,898,268...69,927,885
Ensembl chr14:69,899,128...69,927,938
JBrowse link
G Ncapg2 non-SMC condensin II complex, subunit G2 decreases expression ISO Lucanthone results in decreased expression of NCAPG2 mRNA CTD PMID:21148553 NCBI chr 6:144,291,313...144,362,454
Ensembl chr 6:144,291,974...144,363,947
JBrowse link
G Ncaph non-SMC condensin I complex, subunit H decreases expression ISO Lucanthone results in decreased expression of NCAPH mRNA CTD PMID:21148553 NCBI chr 3:119,583,798...119,611,148
Ensembl chr 3:119,583,648...119,611,136
JBrowse link
G Ndc80 NDC80 kinetochore complex component decreases expression ISO Lucanthone results in decreased expression of NDC80 mRNA CTD PMID:21148553 NCBI chr 9:119,837,857...119,871,435
Ensembl chr 9:119,839,016...119,871,382
JBrowse link
G Nek2 NIMA-related kinase 2 decreases expression ISO Lucanthone results in decreased expression of NEK2 mRNA CTD PMID:21148553 NCBI chr13:110,511,546...110,524,750
Ensembl chr13:110,511,668...110,522,769
JBrowse link
G Nemp1 nuclear envelope integral membrane protein 1 decreases expression ISO Lucanthone results in decreased expression of NEMP1 mRNA CTD PMID:21148553 NCBI chr 7:70,987,860...70,996,029
Ensembl chr 7:70,987,861...70,995,474
JBrowse link
G Niban1 niban apoptosis regulator 1 decreases expression ISO Lucanthone results in decreased expression of NIBAN1 mRNA CTD PMID:21148553 NCBI chr13:68,949,665...69,101,600
Ensembl chr13:68,949,665...69,101,588
JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 increases expression ISO Lucanthone results in increased expression of NR4A2 mRNA CTD PMID:21148553 NCBI chr 3:43,111,258...43,128,391
Ensembl chr 3:43,111,240...43,119,159
JBrowse link
G Nuf2 NUF2 component of NDC80 kinetochore complex decreases expression ISO Lucanthone results in decreased expression of NUF2 mRNA CTD PMID:21148553 NCBI chr13:87,818,456...87,847,223
Ensembl chr13:87,818,391...87,847,263
JBrowse link
G Nusap1 nucleolar and spindle associated protein 1 decreases expression ISO Lucanthone results in decreased expression of NUSAP1 mRNA CTD PMID:21148553 NCBI chr 3:111,422,267...111,452,600
Ensembl chr 3:111,422,267...111,452,971
JBrowse link
G Orc6 origin recognition complex, subunit 6 decreases expression ISO Lucanthone results in decreased expression of ORC6 mRNA CTD PMID:21148553 NCBI chr19:27,457,541...27,464,804
Ensembl chr19:27,457,474...27,464,805
JBrowse link
G Otub2 OTU deubiquitinase, ubiquitin aldehyde binding 2 increases expression ISO Lucanthone results in increased expression of OTUB2 mRNA CTD PMID:21148553 NCBI chr 6:127,282,445...127,301,086
Ensembl chr 6:127,282,466...127,301,083
JBrowse link
G Pbk PDZ binding kinase decreases expression ISO Lucanthone results in decreased expression of PBK mRNA CTD PMID:21148553 NCBI chr15:42,489,253...42,500,377
Ensembl chr15:42,489,377...42,500,395
JBrowse link
G Pclaf PCNA clamp associated factor decreases expression ISO Lucanthone results in decreased expression of PCLAF mRNA CTD PMID:21148553 NCBI chr 8:71,514,281...71,526,182
Ensembl chr 8:71,514,281...71,526,182
JBrowse link
G Phgdh phosphoglycerate dehydrogenase decreases expression ISO Lucanthone results in decreased expression of PHGDH mRNA CTD PMID:21148553 NCBI chr 2:200,484,245...200,513,564
Ensembl chr 2:200,484,246...200,513,564
JBrowse link
G Plk1 polo-like kinase 1 decreases expression ISO Lucanthone results in decreased expression of PLK1 mRNA CTD PMID:21148553 NCBI chr 1:192,115,990...192,125,969
Ensembl chr 1:192,115,966...192,125,989
JBrowse link
G Plk4 polo-like kinase 4 decreases expression ISO Lucanthone results in decreased expression of PLK4 mRNA CTD PMID:21148553 NCBI chr 2:127,686,911...127,705,518
Ensembl chr 2:127,686,925...127,705,518
JBrowse link
G Pole2 DNA polymerase epsilon 2, accessory subunit decreases expression ISO Lucanthone results in decreased expression of POLE2 mRNA CTD PMID:21148553 NCBI chr 6:91,494,348...91,532,355
Ensembl chr 6:91,494,393...91,518,996
JBrowse link
G Prc1 protein regulator of cytokinesis 1 decreases expression ISO Lucanthone results in decreased expression of PRC1 mRNA CTD PMID:21148553 NCBI chr 1:142,087,181...142,108,746
Ensembl chr 1:142,087,208...142,108,746
JBrowse link
G Prim1 DNA primase subunit 1 decreases expression ISO Lucanthone results in decreased expression of PRIM1 mRNA CTD PMID:21148553 NCBI chr 7:2,435,524...2,451,169
Ensembl chr 7:2,435,553...2,451,165
JBrowse link
G Prr11 proline rich 11 decreases expression ISO Lucanthone results in decreased expression of PRR11 mRNA CTD PMID:21148553 NCBI chr10:74,393,683...74,436,073
Ensembl chr10:74,393,699...74,413,745
JBrowse link
G Psat1 phosphoserine aminotransferase 1 decreases expression ISO Lucanthone results in decreased expression of PSAT1 mRNA CTD PMID:21148553 NCBI chr 1:233,124,089...233,145,941
Ensembl chr 1:233,124,092...233,145,941
JBrowse link
G Psmc3ip PSMC3 interacting protein decreases expression ISO Lucanthone results in decreased expression of PSMC3IP mRNA CTD PMID:21148553 NCBI chr10:89,002,109...89,006,075
Ensembl chr10:89,002,116...89,005,213
JBrowse link
G Ptchd4 patched domain containing 4 increases expression ISO Lucanthone results in increased expression of PTCHD4 mRNA CTD PMID:21148553 NCBI chr 9:21,137,150...21,339,398
Ensembl chr 9:21,141,077...21,338,582
JBrowse link
G Pxdn peroxidasin increases expression ISO Lucanthone results in increased expression of PXDN mRNA CTD PMID:21148553 NCBI chr 6:48,866,496...48,982,368
Ensembl chr 6:48,866,601...48,980,340
JBrowse link
G Racgap1 Rac GTPase-activating protein 1 decreases expression ISO Lucanthone results in decreased expression of RACGAP1 mRNA CTD PMID:21148553 NCBI chr 7:141,277,303...141,308,849
Ensembl chr 7:141,277,312...141,307,233
JBrowse link
G Rad51 RAD51 recombinase decreases expression ISO Lucanthone results in decreased expression of RAD51 mRNA CTD PMID:21148553 NCBI chr 3:110,918,240...110,942,920
Ensembl chr 3:110,918,243...110,942,917
JBrowse link
G Rad51ap1 RAD51 associated protein 1 decreases expression ISO Lucanthone results in decreased expression of RAD51AP1 mRNA CTD PMID:21148553 NCBI chr 4:159,469,803...159,482,869
Ensembl chr 4:159,469,804...159,482,869
JBrowse link
G RGD1306227 similar to 4833420G17Rik protein decreases expression ISO Lucanthone results in decreased expression of C5ORF34 mRNA CTD PMID:21148553 NCBI chr 2:52,333,396...52,355,044
Ensembl chr 2:52,333,396...52,355,042
JBrowse link
G RGD1562378 histone H4 variant H4-v.1 increases expression ISO Lucanthone results in increased expression of H4C14 mRNA CTD PMID:21148553 NCBI chr 4:170,762,862...170,763,962
Ensembl chr 4:170,763,605...170,763,916
JBrowse link
G Rrm2 ribonucleotide reductase regulatory subunit M2 decreases expression ISO Lucanthone results in decreased expression of RRM2 mRNA CTD PMID:21148553 NCBI chr 6:43,884,627...43,890,818
Ensembl chr 6:43,884,678...43,889,515
JBrowse link
G Sat1 spermidine/spermine N1-acetyl transferase 1 increases expression ISO Lucanthone results in increased expression of SAT1 mRNA CTD PMID:21148553 NCBI chr  X:43,626,480...43,629,767
Ensembl chr  X:43,625,169...43,629,765
JBrowse link
G Scube1 signal peptide, CUB domain and EGF like domain containing 1 increases expression ISO Lucanthone results in increased expression of SCUBE1 mRNA CTD PMID:21148553 NCBI chr 7:124,501,988...124,620,755
Ensembl chr 7:124,501,988...124,620,703
JBrowse link
G Sectm1b secreted and transmembrane 1B increases expression ISO Lucanthone results in increased expression of SECTM1 mRNA CTD PMID:21148553 NCBI chr10:110,251,363...110,260,577
Ensembl chr10:110,251,363...110,259,985
JBrowse link
G Serpinb2 serpin family B member 2 increases expression ISO Lucanthone results in increased expression of SERPINB2 mRNA CTD PMID:21148553 NCBI chr13:27,449,907...27,463,015
Ensembl chr13:27,449,934...27,463,010
JBrowse link
G Sgo1 shugoshin 1 decreases expression ISO Lucanthone results in decreased expression of SGO1 mRNA CTD PMID:21148553 NCBI chr 9:4,420,158...4,435,939
Ensembl chr 9:4,421,069...4,436,601
JBrowse link
G Sgo2 shugoshin 2 decreases expression ISO Lucanthone results in decreased expression of SGO2 mRNA CTD PMID:21148553 NCBI chr 9:64,898,380...64,923,023
Ensembl chr 9:64,898,459...64,923,012
JBrowse link
G Shc4 SHC adaptor protein 4 increases expression ISO Lucanthone results in increased expression of SHC4 mRNA CTD PMID:21148553 NCBI chr 3:117,897,738...117,990,289
Ensembl chr 3:117,897,738...117,990,289
JBrowse link
G Shcbp1 SHC binding and spindle associated 1 decreases expression ISO Lucanthone results in decreased expression of SHCBP1 mRNA CTD PMID:21148553 NCBI chr16:90,613,826...90,642,683
Ensembl chr16:90,613,870...90,641,420
JBrowse link
G Slc1a4 solute carrier family 1 member 4 decreases expression ISO Lucanthone results in decreased expression of SLC1A4 mRNA CTD PMID:21148553 NCBI chr14:104,582,884...104,612,417
Ensembl chr14:104,581,190...104,612,597
JBrowse link
G Smc4 structural maintenance of chromosomes 4 decreases expression ISO Lucanthone results in decreased expression of SMC4 mRNA CTD PMID:21148553 NCBI chr 2:165,600,934...165,629,415
Ensembl chr 2:165,601,007...165,629,415
JBrowse link
G Spag5 sperm associated antigen 5 decreases expression ISO Lucanthone results in decreased expression of SPAG5 mRNA CTD PMID:21148553 NCBI chr10:65,552,780...65,585,773
Ensembl chr10:65,566,171...65,585,760
Ensembl chr10:65,566,171...65,585,760
JBrowse link
G Spata18 spermatogenesis associated 18 increases expression ISO Lucanthone results in increased expression of SPATA18 mRNA CTD PMID:21148553 NCBI chr14:37,081,529...37,108,245
Ensembl chr14:37,081,427...37,108,341
JBrowse link
G Spc25 SPC25 component of NDC80 kinetochore complex decreases expression ISO Lucanthone results in decreased expression of SPC25 mRNA CTD PMID:21148553 NCBI chr 3:55,438,534...55,451,961
Ensembl chr 3:55,438,536...55,451,798
JBrowse link
G Spdl1 spindle apparatus coiled-coil protein 1 decreases expression ISO Lucanthone results in decreased expression of SPDL1 mRNA CTD PMID:21148553 NCBI chr10:19,628,070...19,652,914
Ensembl chr10:19,628,258...19,652,898
JBrowse link
G Stmn1 stathmin 1 decreases expression ISO Lucanthone results in decreased expression of STMN1 mRNA CTD PMID:21148553 NCBI chr 5:152,680,412...152,686,807
Ensembl chr 5:152,680,407...152,686,806
JBrowse link
G Sulf2 sulfatase 2 increases expression ISO Lucanthone results in increased expression of SULF2 mRNA CTD PMID:21148553 NCBI chr 3:162,791,349...162,872,984
Ensembl chr 3:162,791,355...162,872,831
JBrowse link
G Tcp11l2 t-complex 11 like 2 increases expression ISO Lucanthone results in increased expression of TCP11L2 mRNA CTD PMID:21148553 NCBI chr 7:24,859,048...24,893,907
Ensembl chr 7:24,859,050...24,885,775
JBrowse link
G Tfpi2 tissue factor pathway inhibitor 2 increases expression ISO Lucanthone results in increased expression of TFPI2 mRNA CTD PMID:21148553 NCBI chr 4:28,947,951...28,953,261
Ensembl chr 4:28,947,965...28,953,067
JBrowse link
G Tiparp TCDD-inducible poly(ADP-ribose) polymerase increases expression ISO Lucanthone results in increased expression of TIPARP mRNA CTD PMID:21148553 NCBI chr 2:157,316,293...157,342,979
Ensembl chr 2:157,316,266...157,341,469
JBrowse link
G Tmem45a transmembrane protein 45A increases expression ISO Lucanthone results in increased expression of TMEM45A mRNA CTD PMID:21148553 NCBI chr11:46,009,216...46,093,969
Ensembl chr11:46,009,322...46,093,973
JBrowse link
G Tnfsf15 TNF superfamily member 15 increases expression ISO Lucanthone results in increased expression of TNFSF15 mRNA CTD PMID:21148553 NCBI chr 5:79,553,935...79,569,974
Ensembl chr 5:79,553,742...79,570,073
JBrowse link
G Top2a DNA topoisomerase II alpha decreases expression ISO Lucanthone results in decreased expression of TOP2A mRNA CTD PMID:21148553 NCBI chr10:86,901,467...86,930,947
Ensembl chr10:86,901,007...86,932,154
JBrowse link
G Tp53i3 tumor protein p53 inducible protein 3 increases expression ISO Lucanthone results in increased expression of TP53I3 mRNA CTD PMID:21148553 NCBI chr13:75,101,759...75,145,967
Ensembl chr13:75,105,615...75,143,441
JBrowse link
G Tp53inp1 tumor protein p53 inducible nuclear protein 1 increases expression ISO Lucanthone results in increased expression of TP53INP1 mRNA CTD PMID:21148553 NCBI chr 5:24,402,895...24,419,651
Ensembl chr 5:24,410,863...24,416,888
JBrowse link
G Tpx2 TPX2, microtubule nucleation factor decreases expression ISO Lucanthone results in decreased expression of TPX2 mRNA CTD PMID:21148553 NCBI chr 3:148,327,965...148,370,187
Ensembl chr 3:148,327,965...148,370,187
JBrowse link
G Ttk Ttk protein kinase decreases expression ISO Lucanthone results in decreased expression of TTK mRNA CTD PMID:21148553 NCBI chr 8:91,368,065...91,405,995
Ensembl chr 8:91,368,111...91,405,993
JBrowse link
G Ube2t ubiquitin-conjugating enzyme E2T decreases expression ISO Lucanthone results in decreased expression of UBE2T mRNA CTD PMID:21148553 NCBI chr13:51,790,877...51,801,379
Ensembl chr13:51,795,867...51,801,163
JBrowse link
G Wdr76 WD repeat domain 76 decreases expression ISO Lucanthone results in decreased expression of WDR76 mRNA CTD PMID:21148553 NCBI chr 3:113,445,498...113,479,483
Ensembl chr 3:113,448,877...113,478,215
JBrowse link
G Xrcc2 X-ray repair cross complementing 2 decreases expression ISO Lucanthone results in decreased expression of XRCC2 mRNA CTD PMID:21148553 NCBI chr 4:5,842,013...5,860,516
Ensembl chr 4:5,841,998...5,860,527
JBrowse link
G Zwint ZW10 interacting kinetochore protein decreases expression ISO Lucanthone results in decreased expression of ZWINT mRNA CTD PMID:21148553 NCBI chr20:17,075,781...17,091,715
Ensembl chr20:17,075,771...17,091,766
JBrowse link
metixene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO methixene results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19770
    chemical entity 19769
      atom 19768
        nonmetal atom 19642
          sulfur atom 16250
            sulfur molecular entity 16250
              organosulfur compound 15181
                organosulfur heterocyclic compound 5819
                  thioxanthenes 201
                    (9E)-7-chloro-9-[3-(dimethylamino)propylidene]thioxanthen-1-ol 0
                    (9Z)-7-chloro-9-[3-(dimethylamino)propylidene]thioxanthen-2-ol 0
                    1-methyl-4-(9-thioxanthenylidene)piperidine 0
                    2-(2,6-dimethyl-4-morpholinyl)-N-[5-[6-(4-morpholinyl)-4-oxo-2-pyranyl]-9H-thioxanthen-2-yl]acetamide 0
                    2-[4-[3-[2-(trifluoromethyl)-9-thioxanthenylidene]propyl]-1-piperazinyl]ethanol 5
                    Chloroprothixene sulfoxide 0
                    N,N-dimethyl-9-[3-(1-piperazinyl)propylidene]-2-thioxanthenesulfonamide 0
                    N,N-dimethyl-9-[3-(4-methyl-1-piperazinyl)propylidene]-2-thioxanthenesulfonamide 0
                    chlorprothixene + 3
                    cis-(z)-Flupenthixol 0
                    clopenthixol + 1
                    flupenthixol 5
                    hycanthone 1
                    lucanthone + 194
                    meprotixol 0
                    metixene + 1
                    thioxanthene + 0
                    zuclopenthixol acetate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19770
    subatomic particle 19768
      composite particle 19768
        hadron 19768
          baryon 19768
            nucleon 19768
              atomic nucleus 19768
                atom 19768
                  main group element atom 19655
                    p-block element atom 19655
                      carbon group element atom 19550
                        carbon atom 19539
                          organic molecular entity 19539
                            organic molecule 19461
                              organic cyclic compound 19232
                                organic heterocyclic compound 18404
                                  organic heteropolycyclic compound 17812
                                    organic heterotricyclic compound 14569
                                      thioxanthenes 201
                                        (9E)-7-chloro-9-[3-(dimethylamino)propylidene]thioxanthen-1-ol 0
                                        (9Z)-7-chloro-9-[3-(dimethylamino)propylidene]thioxanthen-2-ol 0
                                        1-methyl-4-(9-thioxanthenylidene)piperidine 0
                                        2-(2,6-dimethyl-4-morpholinyl)-N-[5-[6-(4-morpholinyl)-4-oxo-2-pyranyl]-9H-thioxanthen-2-yl]acetamide 0
                                        2-[4-[3-[2-(trifluoromethyl)-9-thioxanthenylidene]propyl]-1-piperazinyl]ethanol 5
                                        Chloroprothixene sulfoxide 0
                                        N,N-dimethyl-9-[3-(1-piperazinyl)propylidene]-2-thioxanthenesulfonamide 0
                                        N,N-dimethyl-9-[3-(4-methyl-1-piperazinyl)propylidene]-2-thioxanthenesulfonamide 0
                                        chlorprothixene + 3
                                        cis-(z)-Flupenthixol 0
                                        clopenthixol + 1
                                        flupenthixol 5
                                        hycanthone 1
                                        lucanthone + 194
                                        meprotixol 0
                                        metixene + 1
                                        thioxanthene + 0
                                        zuclopenthixol acetate 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.