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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:allergen
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Accession:CHEBI:50904 term browser browse the term
Definition:A chemical compound, or part thereof, which causes the onset of an allergic reaction by interacting with any of the molecular pathways involved in an allergy.
Synonyms:related_synonym: alergeno;   allergene;   allergenic agent
 xref: Wikipedia:Allergen


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1,2-dihexadecanoyl-sn-glycero-3-phosphocholine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PLCG1 phospholipase C gamma 1 decreases activity
multiple interactions		 EXP 1,2-Dipalmitoylphosphatidylcholine results in decreased activity of PLCG1 protein
dipalmitoylphosphatidic acid inhibits the reaction [1,2-Dipalmitoylphosphatidylcholine results in decreased activity of PLCG1 protein]		 CTD PMID:2001791 NCBI chr24:29,198,536...29,213,899
Ensembl chr24:29,198,556...29,214,714 		JBrowse link
1,4-phenylenediamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CASP8 caspase 8 increases activity
multiple interactions		 EXP 4-phenylenediamine results in increased activity of CASP8 protein
benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [4-phenylenediamine results in increased activity of CASP8 protein]		 CTD PMID:20156547 NCBI chr37:10,362,071...10,402,108
Ensembl chr37:10,391,048...10,401,822 		JBrowse link
G CASP9 caspase 9 multiple interactions
increases activity		 EXP benzyloxycarbonyl-leucyl-glutamyl-histidyl-aspartic acid fluoromethyl ketone inhibits the reaction [4-phenylenediamine results in increased activity of CASP9 protein] CTD PMID:20156547 NCBI chr 2:82,033,759...82,076,710
Ensembl chr 2:82,031,563...82,090,484 		JBrowse link
acetylsalicylic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PTGS1 prostaglandin-endoperoxide synthase 1 decreases activity EXP Aspirin results in decreased activity of PTGS1 protein alternative form CTD PMID:12242329 NCBI chr 9:60,195,118...60,216,847
Ensembl chr 9:60,195,124...60,216,819 		JBrowse link
atropine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACHE acetylcholinesterase multiple interactions EXP [Obidoxime Chloride co-treated with Atropine] inhibits the reaction [Sarin results in decreased activity of ACHE protein]; [Obidoxime Chloride co-treated with Atropine] inhibits the reaction [Soman results in decreased activity of ACHE protein]; [Obidoxime Chloride co-treated with Atropine] inhibits the reaction [VX results in decreased activity of ACHE protein] CTD PMID:16915560 NCBI chr 6:8,874,747...8,879,926
Ensembl chr 6:8,873,584...8,879,702 		JBrowse link
G SCT secretin multiple interactions EXP Atropine inhibits the reaction [SCT protein results in increased abundance of Bicarbonates] CTD PMID:3562434
cobalt atom term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G VIP vasoactive intestinal peptide decreases expression EXP Cobalt results in decreased expression of VIP protein CTD PMID:3711722 NCBI chr 1:42,941,655...42,950,160
Ensembl chr 1:42,941,224...42,950,700 		JBrowse link
copper atom term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APP amyloid beta precursor protein increases expression EXP Copper results in increased expression of APP protein CTD PMID:16886094 NCBI chr31:21,351,207...21,614,466
Ensembl chr31:21,351,207...21,614,337 		JBrowse link
G COMMD1 copper metabolism domain containing 1 increases abundance
decreases export		 EXP COMMD1 gene mutant form results in increased abundance of Copper
COMMD1 gene mutant form results in decreased export of Copper		 CTD PMID:20433422 PMID:22879914 NCBI chr10:61,886,281...62,059,610
Ensembl chr10:61,886,281...62,059,591 		JBrowse link
copper(0) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APP amyloid beta precursor protein increases expression EXP Copper results in increased expression of APP protein CTD PMID:16886094 NCBI chr31:21,351,207...21,614,466
Ensembl chr31:21,351,207...21,614,337 		JBrowse link
G COMMD1 copper metabolism domain containing 1 increases abundance
decreases export		 EXP COMMD1 gene mutant form results in increased abundance of Copper
COMMD1 gene mutant form results in decreased export of Copper		 CTD PMID:20433422 PMID:22879914 NCBI chr10:61,886,281...62,059,610
Ensembl chr10:61,886,281...62,059,591 		JBrowse link
cortisol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CRH corticotropin releasing hormone increases abundance EXP CRH protein results in increased abundance of Hydrocortisone CTD PMID:2831029 NCBI chr29:15,831,944...15,840,560
Ensembl chr29:15,831,944...15,834,384 		JBrowse link
G INS insulin affects abundance
multiple interactions		 EXP INS protein affects the abundance of Hydrocortisone
Sodium affects the reaction [INS protein affects the abundance of Hydrocortisone]		 CTD PMID:1324617 NCBI chr18:46,324,047...46,324,933
Ensembl chr18:46,324,041...46,325,122 		JBrowse link
G POMC proopiomelanocortin increases abundance EXP POMC protein results in increased abundance of Hydrocortisone CTD PMID:2831029 NCBI chr17:19,431,396...19,438,247
Ensembl chr17:19,431,585...19,434,440 		JBrowse link
cyclophosphamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP2B6 cytochrome P450 2B11 increases hydroxylation EXP CYP2B6 protein results in increased hydroxylation of Cyclophosphamide CTD PMID:16546968 NCBI chr 1:112,817,561...112,833,294
Ensembl chr 1:112,816,502...112,833,293 		JBrowse link
D-mannitol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLDN4 claudin 4 increases expression EXP Mannitol results in increased expression of CLDN4 protein CTD PMID:23816505 NCBI chr 6:6,492,706...6,506,750
Ensembl chr 6:6,493,513...6,494,145 		JBrowse link
desipramine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP2D15 cytochrome P450 family 2 subfamily D member 15 affects metabolic processing EXP CYP2D15 affects the metabolism of Desipramine CTD PMID:7786018 NCBI chr10:23,255,259...23,259,380
Ensembl chr10:23,255,249...23,259,298 		JBrowse link
diclofenac term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP2C41 cytochrome P450 2C41 affects metabolic processing
increases hydroxylation		 EXP CYP2C9 protein affects the metabolism of Diclofenac
CYP2C19 protein results in increased hydroxylation of Diclofenac		 CTD PMID:15677349 PMID:15801540
G PTGS1 prostaglandin-endoperoxide synthase 1 decreases activity EXP Diclofenac results in decreased activity of PTGS1 protein alternative form CTD PMID:12242329 NCBI chr 9:60,195,118...60,216,847
Ensembl chr 9:60,195,124...60,216,819 		JBrowse link
eplerenone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AR androgen receptor multiple interactions EXP Eplerenone binds to and results in decreased activity of AR protein CTD PMID:23242577 NCBI chr24:34,713,390...34,731,461
NCBI chr  X:51,969,785...52,167,450
Ensembl chr  X:51,969,785...52,151,912 		JBrowse link
ibuprofen term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PTGS1 prostaglandin-endoperoxide synthase 1 decreases activity EXP Ibuprofen results in decreased activity of PTGS1 protein alternative form CTD PMID:12242329 NCBI chr 9:60,195,118...60,216,847
Ensembl chr 9:60,195,124...60,216,819 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 increases expression EXP Ibuprofen results in increased expression of PTGS2 protein CTD PMID:16105799 NCBI chr 7:19,668,079...19,674,903
Ensembl chr 7:19,668,082...19,674,903 		JBrowse link
paracetamol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PTGS1 prostaglandin-endoperoxide synthase 1 decreases activity EXP Acetaminophen results in decreased activity of PTGS1 protein alternative form CTD PMID:12242329 NCBI chr 9:60,195,118...60,216,847
Ensembl chr 9:60,195,124...60,216,819 		JBrowse link
G UGT1A6 UDP glucuronosyltransferase 1 family, polypeptide A6 increases glucuronidation EXP UGT1A6 protein results in increased glucuronidation of Acetaminophen CTD PMID:11903872 NCBI chr25:45,081,655...45,161,584
Ensembl chr25:45,032,130...45,160,941 		JBrowse link
phenacetin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 affects metabolic processing EXP CYP1A2 protein affects the metabolism of Phenacetin CTD PMID:15801540 NCBI chr30:37,818,400...37,824,192
Ensembl chr30:37,799,140...37,824,135 		JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 decreases activity EXP Phenacetin results in decreased activity of PTGS1 protein alternative form CTD PMID:12242329 NCBI chr 9:60,195,118...60,216,847
Ensembl chr 9:60,195,124...60,216,819 		JBrowse link
phenobarbital term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACAA1 acetyl-CoA acyltransferase 1 decreases expression EXP Phenobarbital results in decreased expression of ACAA1 mRNA CTD PMID:19952500 NCBI chr23:7,889,481...7,901,324
Ensembl chr23:7,889,500...7,901,229 		JBrowse link
G ACAA2 acetyl-CoA acyltransferase 2 decreases expression EXP Phenobarbital results in decreased expression of ACAA2 mRNA CTD PMID:19952500 NCBI chr 7:79,028,636...79,057,720 JBrowse link
G ACOX2 acyl-CoA oxidase 2 decreases expression EXP Phenobarbital results in decreased expression of ACOX2 mRNA CTD PMID:19952500 NCBI chr20:32,110,788...32,141,751
Ensembl chr20:32,113,217...32,141,734 		JBrowse link
G AGXT alanine--glyoxylate and serine--pyruvate aminotransferase decreases expression EXP Phenobarbital results in decreased expression of AGXT protein CTD PMID:19952500 NCBI chr25:50,968,291...50,976,089 JBrowse link
G AHCY adenosylhomocysteinase decreases expression EXP Phenobarbital results in decreased expression of AHCY protein CTD PMID:19952500 NCBI chr24:23,410,553...23,423,494
Ensembl chr24:23,411,140...23,419,767 		JBrowse link
G ASL argininosuccinate lyase decreases expression EXP Phenobarbital results in decreased expression of ASL protein CTD PMID:19952500 NCBI chr 6:768,522...779,144
Ensembl chr 6:730,358...779,424 		JBrowse link
G ASS1 argininosuccinate synthase 1 decreases expression EXP Phenobarbital results in decreased expression of ASS1 protein CTD PMID:19952500 NCBI chr 9:53,425,228...53,478,007
Ensembl chr 9:53,425,448...53,477,904 		JBrowse link
G BHMT betaine--homocysteine S-methyltransferase decreases expression EXP Phenobarbital results in decreased expression of BHMT protein CTD PMID:19952500 NCBI chr 3:27,732,381...27,752,168
Ensembl chr 3:27,734,108...27,752,046 		JBrowse link
G CA3 carbonic anhydrase 3 decreases expression EXP Phenobarbital results in decreased expression of CA3 protein CTD PMID:19952500 NCBI chr29:31,935,192...31,945,585
Ensembl chr29:31,935,172...31,980,579 		JBrowse link
G CPT1A carnitine palmitoyltransferase 1A decreases expression EXP Phenobarbital results in decreased expression of CPT1A mRNA CTD PMID:19952500 NCBI chr18:49,136,691...49,190,117
Ensembl chr18:49,136,691...49,190,117 		JBrowse link
G CRYZ crystallin zeta increases expression EXP Phenobarbital results in increased expression of CRYZ protein CTD PMID:19952500 NCBI chr 6:71,656,162...71,693,020
Ensembl chr 6:71,656,188...71,675,692 		JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 decreases expression EXP Phenobarbital results in decreased expression of CYP1A2 mRNA CTD PMID:19952500 NCBI chr30:37,818,400...37,824,192
Ensembl chr30:37,799,140...37,824,135 		JBrowse link
G CYP2A13 cytochrome P450 family 2 subfamily A polypeptide 13 decreases expression EXP Phenobarbital results in decreased expression of CYP2A13 mRNA CTD PMID:19952500 NCBI chr 1:112,932,246...112,938,248
Ensembl chr 1:112,931,985...112,938,350 		JBrowse link
G CYP2B6 cytochrome P450 2B11 increases expression EXP Phenobarbital results in increased expression of CYP2B6 protein CTD PMID:19952500 NCBI chr 1:112,817,561...112,833,294
Ensembl chr 1:112,816,502...112,833,293 		JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 decreases expression EXP Phenobarbital results in decreased expression of CYP2E1 mRNA CTD PMID:19952500 NCBI chr28:41,079,164...41,089,188
Ensembl chr28:41,035,025...41,122,754 		JBrowse link
G CYP3A12 cytochrome P-450 3A12 increases expression EXP Phenobarbital results in increased expression of CYP3A12 protein CTD PMID:19952500
G CYP3A26 cytochrome P450 3A26 increases expression EXP Phenobarbital results in increased expression of CYP3A26 mRNA CTD PMID:19952500 NCBI chr 6:9,777,663...9,815,345
Ensembl chr 6:9,777,659...9,869,352 		JBrowse link
G CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 increases expression EXP Phenobarbital results in increased expression of CYP3A4 mRNA CTD PMID:19952500 NCBI chr 6:9,836,685...9,869,520
Ensembl chr 6:9,777,659...9,869,352 		JBrowse link
G CYP4A11 cytochrome P450, family 4, subfamily A, polypeptide 11 decreases expression EXP Phenobarbital results in decreased expression of CYP4A11 mRNA CTD PMID:19952500 NCBI chr15:13,663,337...13,676,350
Ensembl chr15:13,604,130...13,676,344 		JBrowse link
G EHHADH enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase decreases expression EXP Phenobarbital results in decreased expression of EHHADH mRNA CTD PMID:19952500 NCBI chr34:18,021,047...18,080,993
Ensembl chr34:18,022,353...18,080,903 		JBrowse link
G FTCD formimidoyltransferase cyclodeaminase increases expression EXP Phenobarbital results in increased expression of FTCD protein CTD PMID:19952500 NCBI chr31:39,451,557...39,464,249
Ensembl chr31:39,275,159...39,464,715 		JBrowse link
G GOT1 glutamic-oxaloacetic transaminase 1 decreases expression EXP Phenobarbital results in decreased expression of GOT1 protein CTD PMID:19952500 NCBI chr28:12,352,658...12,377,960
Ensembl chr28:12,352,659...12,414,579 		JBrowse link
G GSTA4 glutathione S-transferase alpha 4 decreases expression EXP Phenobarbital results in decreased expression of GSTA4 mRNA CTD PMID:19952500 NCBI chr12:20,426,724...20,443,200
Ensembl chr12:20,426,726...20,443,200 		JBrowse link
G GSTO1 glutathione S-transferase omega 1 increases expression EXP Phenobarbital results in increased expression of GSTO1 mRNA CTD PMID:19952500 NCBI chr28:16,569,421...16,579,239
Ensembl chr28:16,569,066...16,619,880 		JBrowse link
G HADH hydroxyacyl-CoA dehydrogenase decreases expression EXP Phenobarbital results in decreased expression of HADH mRNA CTD PMID:19952500 NCBI chr32:28,460,445...28,506,141
Ensembl chr32:28,460,193...28,531,280 		JBrowse link
G HPD 4-hydroxyphenylpyruvate dioxygenase decreases expression EXP Phenobarbital results in decreased expression of HPD protein CTD PMID:19952500 NCBI chr26:7,430,891...7,440,643
Ensembl chr26:7,430,933...7,440,611 		JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 increases expression EXP Phenobarbital results in increased expression of HSPA5 protein CTD PMID:19952500 NCBI chr 9:57,850,870...57,855,607
Ensembl chr 9:57,850,922...57,855,257 		JBrowse link
G IDH1 isocitrate dehydrogenase (NADP(+)) 1 decreases expression EXP Phenobarbital results in decreased expression of IDH1 protein CTD PMID:19952500 NCBI chr37:16,512,027...16,531,269
Ensembl chr37:16,512,770...16,531,219 		JBrowse link
G LOC474938 glutathione S-transferase A2 increases expression EXP Phenobarbital results in increased expression of GSTA3 protein CTD PMID:19952500 NCBI chr12:20,349,133...20,365,023 JBrowse link
G LOC477540 SEC14-like protein 3 decreases expression EXP Phenobarbital results in decreased expression of SEC14L3 protein CTD PMID:19952500 NCBI chr26:23,580,899...23,590,676
Ensembl chr26:23,580,901...23,590,622 		JBrowse link
G LOC479912 glutathione S-transferase Mu 1 decreases expression EXP Phenobarbital results in decreased expression of GSTM1 mRNA CTD PMID:19952500 NCBI chr 6:42,201,697...42,207,886 JBrowse link
G LOC486353 SEC14-like protein 4 decreases expression EXP Phenobarbital results in decreased expression of SEC14L4 protein CTD PMID:19952500 NCBI chr26:23,598,434...23,611,727
Ensembl chr26:23,600,237...23,618,123 		JBrowse link
G MGST1 microsomal glutathione S-transferase 1 increases expression EXP Phenobarbital results in increased expression of MGST1 mRNA CTD PMID:19952500 NCBI chr27:30,370,588...30,391,898
Ensembl chr27:30,370,594...30,391,778 		JBrowse link
G MGST2 microsomal glutathione S-transferase 2 increases expression EXP Phenobarbital results in increased expression of MGST2 mRNA CTD PMID:19952500 NCBI chr19:3,067,062...3,070,579 JBrowse link
G MGST3 microsomal glutathione S-transferase 3 decreases expression EXP Phenobarbital results in decreased expression of MGST3 mRNA CTD PMID:19952500 NCBI chr38:17,670,329...17,691,822
Ensembl chr38:17,668,752...17,718,704 		JBrowse link
G PAH phenylalanine hydroxylase decreases expression EXP Phenobarbital results in decreased expression of PAH protein CTD PMID:19952500 NCBI chr15:41,590,253...41,670,156
Ensembl chr15:41,592,876...41,670,837 		JBrowse link
G PDIA3 protein disulfide isomerase family A member 3 increases expression EXP Phenobarbital results in increased expression of PDIA3 protein CTD PMID:19952500 NCBI chr30:10,487,926...10,513,437
Ensembl chr30:10,487,921...10,513,397 		JBrowse link
G PRDX6 peroxiredoxin 6 decreases expression EXP Phenobarbital results in decreased expression of PRDX6 protein CTD PMID:19952500 NCBI chr 7:25,663,238...25,675,855
Ensembl chr 7:25,663,579...25,675,754 		JBrowse link
G SELENBP1 selenium binding protein 1 decreases expression EXP Phenobarbital results in decreased expression of SELENBP1 protein CTD PMID:19952500 NCBI chr17:60,410,727...60,418,770
Ensembl chr17:60,410,734...60,418,704 		JBrowse link
G SOD1 superoxide dismutase 1 affects response to substance EXP SOD1 protein affects the susceptibility to Phenobarbital CTD PMID:6333936 NCBI chr31:26,540,291...26,544,212
Ensembl chr31:26,486,274...26,662,815 		JBrowse link
G UGDH UDP-glucose 6-dehydrogenase increases expression EXP Phenobarbital results in increased expression of UGDH protein CTD PMID:19952500 NCBI chr 3:72,935,532...72,964,151
Ensembl chr 3:72,839,920...72,963,208 		JBrowse link
G UGT2B31 UDP-glucuronosyltransferase UGT2B31 increases expression EXP Phenobarbital results in increased expression of UGT2B4 protein CTD PMID:19952500 NCBI chr13:58,993,957...59,007,420 JBrowse link
G UROC1 urocanate hydratase 1 decreases expression EXP Phenobarbital results in decreased expression of UROC1 protein CTD PMID:19952500 NCBI chr20:676,624...717,109
Ensembl chr20:678,073...717,141 		JBrowse link
salicylamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AHR aryl hydrocarbon receptor multiple interactions EXP [salicylamide binds to and results in decreased activity of AHR protein] which results in decreased susceptibility to prochloraz; [salicylamide binds to and results in decreased activity of AHR protein] which results in decreased susceptibility to Tetrachlorodibenzodioxin CTD PMID:24389113 NCBI chr14:31,743,704...31,793,484
Ensembl chr14:31,686,170...31,791,444 		JBrowse link
styrene oxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP3A12 cytochrome P-450 3A12 multiple interactions EXP CYP3A12 protein promotes the reaction [EPHX1 protein affects the hydrolysis of styrene oxide] CTD PMID:12051674
G EPHX1 epoxide hydrolase 1 multiple interactions EXP CYP3A12 protein promotes the reaction [EPHX1 protein affects the hydrolysis of styrene oxide] CTD PMID:12051674 NCBI chr 7:38,964,319...39,004,902
Ensembl chr 7:38,964,338...38,999,238 		JBrowse link
succinylcholine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCHE butyrylcholinesterase increases hydrolysis
multiple interactions		 EXP BCHE protein results in increased hydrolysis of Succinylcholine
Succinylcholine inhibits the reaction [BCHE protein results in increased hydrolysis of butyrylcholine]		 CTD PMID:4985882 NCBI chr34:30,912,632...30,977,624
Ensembl chr34:30,912,632...30,977,583 		JBrowse link
troleandomycin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NR1I2 nuclear receptor subfamily 1 group I member 2 increases activity EXP Troleandomycin results in increased activity of NR1I2 protein CTD PMID:27732639 NCBI chr33:23,444,367...23,456,405
Ensembl chr33:23,432,690...23,455,347 		JBrowse link
tropan-3alpha-yl 3-hydroxy-2-phenylpropanoate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACHE acetylcholinesterase multiple interactions EXP [Obidoxime Chloride co-treated with Atropine] inhibits the reaction [Sarin results in decreased activity of ACHE protein]; [Obidoxime Chloride co-treated with Atropine] inhibits the reaction [Soman results in decreased activity of ACHE protein]; [Obidoxime Chloride co-treated with Atropine] inhibits the reaction [VX results in decreased activity of ACHE protein] CTD PMID:16915560 NCBI chr 6:8,874,747...8,879,926
Ensembl chr 6:8,873,584...8,879,702 		JBrowse link
G SCT secretin multiple interactions EXP Atropine inhibits the reaction [SCT protein results in increased abundance of Bicarbonates] CTD PMID:3562434
UTP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G P2RY2 purinergic receptor P2Y2 multiple interactions
increases activity		 EXP [Uridine Triphosphate results in increased activity of P2RY2 protein] which results in increased abundance of Arachidonic Acid; [Uridine Triphosphate results in increased activity of P2RY2 protein] which results in increased abundance of Cyclic AMP; pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [[Uridine Triphosphate results in increased activity of P2RY2 protein] which results in increased abundance of Arachidonic Acid]; pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [[Uridine Triphosphate results in increased activity of P2RY2 protein] which results in increased abundance of Cyclic AMP] CTD PMID:10604969 NCBI chr21:24,987,568...25,009,754
Ensembl chr21:24,992,848...24,996,059 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 499
    role 499
      biological role 499
        aetiopathogenetic role 397
          allergen 66
            (2-sulfonatophenyl)azo group 0
            (2R)-2-\{(1R)-1-hydroxy-15-[2-(20-methoxy-21-methylnonatriacontyl)cyclopropyl]pentadecyl\}hexacosanoic acid + 0
            (3-sulfonatophenyl)azo group 0
            (4-sulfonatophenyl)azo group 0
            (4R)-limonene 1-hydroperoxide 0
            (4R)-limonene 2-hydroperoxide 0
            (5R)-5-isopropenyl-1,2-dimethylcyclohexane 1-hydroperoxide 0
            (5R)-5-isopropenyl-2-methylcyclohexane 1-hydroperoxide 0
            (5R)-5-isopropyl-2-methyl-2-cyclohexen-1-one 0
            (8Z,11Z)-urushiol III 0
            1,2-bis(diphenylphosphino)ethane 0
            1,3-diphenylguanidine + 0
            1,4-phenylenediamine + 2
            1-(2,6,6-trimethylcyclohex-2-en-1-yl)but-2-enone 0
            1-O-(alpha-D-galactosyl)-N-hexacosanoylphytosphingosine + 0
            1-chloro-2,4,6-trinitrobenzene 0
            1-chloro-2,4-dinitrobenzene 0
            1-fluoro-2,4-dinitrobenzene 0
            2,4,6-trinitrophenyl group + 0
            2,4-dinitrophenol + 0
            2,4-dinitrophenyl group + 0
            2,5,5-trimethyl-1,3-thiazolidine-4-carboxylic acid 0
            2,5-diaminotoluene sulfate 0
            2,5-dimethyl-p-phenylenediamine 0
            2-O-alpha-D-mannosyl-1-O-\{1-O-[(10S)-10-methyloctadecanoyl]-2-O-palmitoyl-sn-glycero-3-phosphonato\}-5-O-palmitoyl-6-O-(6-O-palmitoyl-alpha-D-mannosyl)-1D-myo-inositol + 0
            2-O-alpha-D-mannosyl-1-O-\{1-O-[(10S)-10-methyloctadecanoyl]-2-O-palmitoyl-sn-glycero-3-phosphono\}-5-O-palmitoyl-6-O-(6-O-palmitoyl-alpha-D-mannosyl)-1D-myo-inositol 0
            2-O-palmitoyl-2'-O-sulfo-3-O-[(2E,4S,6S,8S)-2,4,6,8-tetramethyltriacont-2-enoyl]-alpha,alpha-trehalose 0
            2-bromo-2-(bromomethyl)pentanedinitrile + 0
            2-hydroxyethyl methacrylate 0
            2-methyl-1,4-phenylenediamine + 0
            2-thienylacetic acid + 0
            2-thiobarbituric acid + 0
            3'-hydroxy-4'-methoxydiclofenac 0
            3'-hydroxydiclofenac 0
            3,4,5-trimethoxycinnamic acid 0
            3,4-dimethoxybenzoic acid + 0
            3,4-dimethoxyphenylethylamine 0
            3-(leucinocarbonyl)phenylazo group 0
            3-pentadecylcatechol 0
            4'-hydroxydiclofenac 0
            4,4'-(ethyl-2-nitropropane-1,3-diyl)bismorpholine 0
            4,4'-azodibenzenearsonic acid 0
            4,4'-diaminodiphenylmethane 0
            4,5,6-trimethyl-3-pentadecylcatechol 0
            4-(2-hydroxy-5-methylphenylazo)acetanilide 0
            4-(2-nitrobutyl)morpholine 0
            4-(4-nitrophenylazo)aniline 0
            4-(ethoxymethylene)-2-phenyloxazol-5-one 0
            4-(phenylazo)aniline 0
            4-aminobenzenesulfonic acid 0
            4-aminobenzoic acid + 0
            4-aminobutyl alpha-L-fucopyranoside 0
            4-aminophenol + 3
            4-chlorobenzoyl group 0
            4-isopropyl-1-methylcyclohexane 1-hydroperoxide 0
            4-methylaminophenol + 0
            4-nitrobenzyl bromide 0
            4-nitrosobenzenesulfonamide 0
            4-sulfanilamidobenzoic acid 0
            4-tert-butylphenol + 0
            4-tolyl isocyanate 0
            5,6-dimethyl-3-pentadecylcatechol 0
            5-(dimethylamino)-N-(4-nitrosobenzyl)naphthalene-1-sulfonamide 0
            5-[2-(2-oxoethoxy)ethoxy]-diclofenac 0
            5-hydroxydiclofenac 0
            6-aminopenicillanic acid + 0
            6-methylcoumarin 0
            6-tuliposide A 0
            Bandrowski's base 0
            Bismark brown Y 0
            D-mannitol + 1
            Disperse Blue 124 0
            Disperse Red 1 0
            N(4)-[alpha-L-fucosyl-(1->3)-N-acetyl-4-O-glycosyl-D-glucosaminyl]-L-asparagine residue 0
            N,N'-dibutylthiourea 0
            N,N'-diethylthiourea 0
            N,N'-diphenylthiourea 0
            N,S-isopropylidene-D-penicillamine 0
            N-(p-hydroxyphenyl)glycine 0
            N-isopropyl-N'-phenyl-p-phenylenediamine 0
            N-phenylglycine 0
            SQ 26,992 0
            alpha-D-Gal-(1->3)-beta-D-Gal-(1->4)-D-GlcNAc + 0
            alpha-D-fucose + 0
            alpha-L-Fucp-(1->3)-[alpha-D-Manp-(1->3)-[alpha-D-Manp-(1->6)]-beta-D-Manp-(1->4)-beta-D-GlcpNAc-(1->4)]-D-GlcpNAc + 0
            alpha-L-arabinofuranose + 0
            ammonium persulfate 0
            ammonium thioglycolate 0
            amoxicillin diketopiperazine 0
            amoxicilloic acid 0
            anthrarobin 0
            artemorin 0
            aztreonyl group + 0
            barbituric acid + 0
            benzocaine 0
            benzylamine + 0
            benzylpenicillenate + 0
            benzylpenicillenic acid + 0
            benzylpenicilloyl-benzylamine 0
            benzylpenilloaldehyde 0
            beryllium sulfate + 0
            beta-aminoarteether maleate 0
            beta-lactam antibiotic allergen + 0
            carbamazepine-10,11-epoxide 0
            carbohydrate allergen + 0
            carvone + 0
            ceramide allergen + 0
            chloramine T 0
            choline + 1
            cobalt chloride hexahydrate 0
            cobalt dichloride + 0
            cocamidopropyl betaine 0
            cyclohexyl isocyanate 0
            deacetyllaurenobiolide 0
            dehydroabietic acid 0
            dibenzothiazol-2-yl disulfide 0
            dicyclohexylmethane-4,4'-diisocyanate 0
            diisocyanate + 0
            diphenylmethane monoisocyanate 0
            diphenylmethane-4,4'-diisocyanate 0
            drug allergen + 52
            ethyl isothiocyanate 0
            ethylene glycol dimethacrylate 0
            ethylenediamine dihydrochloride 0
            eugenol + 0
            fluazinam 0
            formaldehyde + 0
            framycetin + 0
            geraniol + 0
            glyceryl monothioglycolate 0
            glyoxal + 0
            hexahydrophthalic anhydride 0
            hexamethylene diisocyanate 0
            hexyl isocyanate 0
            hydroxycitronellal 0
            isoeugenol + 0
            lamivudine 0
            laurenobiolide + 0
            linalool 6-hydroperoxide 0
            linalool 7-hydroperoxide 0
            linalool hydroperoxide + 0
            lissamine fast yellow 0
            lissamine fast yellow (acid form) 0
            litreol 0
            loracarbef anion 0
            maleic anhydride 0
            metal allergen + 3
            metal cation allergen + 0
            methyl isocyanate + 0
            methyl methacrylate 0
            methylhexahydrophthalic anhydride 0
            methyltetrahydrophthalic anhydride 0
            monobenzone 0
            n-butyl isocyanate 0
            neomycin sulfate 0
            nickel sulfate + 0
            nitrososulfadiazine 0
            nitrososulfamethoxazole 0
            nitrososulfapyridine 0
            oxirane + 4
            p-aminodiphenylamine + 0
            patent blue V 0
            penicillin + 0
            penicillin allergen + 0
            penicilloyl group allergen + 0
            peptide allergen + 0
            phenoxyacetic acid + 0
            phenyl isocyanate 0
            phenyl isothiocyanate 0
            phenylacetic acid + 4
            phosphocholine + 0
            phthalic anhydride + 0
            phthalyl group 0
            potassium dichromate 0
            primin 0
            propane-1,2-diol + 0
            pyridine-2-thiol 0
            pyrimidine-2-thiol 0
            quaternium-15 0
            resorcinol monobenzoate 0
            sodium aurothiomalate 0
            sodium aurothiosulfate 0
            sodium hydrogensulfite 0
            squaric acid dibutyl ester 0
            sulfamethoxazole hydroxylamine 0
            sulfapyridine hydroxylamine 0
            tetrachlorophthalic anhydride 0
            tixocortol pivalate 0
            toluene 2,4-diisocyanate 0
            toluene 2,6-diisocyanate 0
            toluene meta-diisocyanate + 0
            triforine 0
            trimellitic anhydride 0
            tulipinolide 0
            tylosin 0
            uracil + 1
            xylitol + 0
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