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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:genotoxin
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Accession:CHEBI:50902 term browser browse the term
Definition:A role played by a chemical compound to induce direct or indirect DNA damage. Such damage can potentially lead to the formation of a malignant tumour, but DNA damage does not lead inevitably to the creation of cancerous cells.
Synonyms:related_synonym: genotoxic agent;   genotoxic agents;   genotoxins
 xref: Wikipedia:Genotoxicity


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  CHEBI ontology 19810
    role 19758
      biological role 19758
        aetiopathogenetic role 18951
          genotoxin 16984
            1,5-dinitronaphthalene 0
            1-naphthol + 167
            2,6-dinitrotoluene 2204
            2-naphthol + 37
            4-methoxyestrone + 0
            7-epi-cylindrospermopsin 0
            MeIQx + 165
            N-(2,6-diethylphenyl)-2-chloroacetamide 0
            N-ethyl-N-nitrosourea 508
            N-hydroxy-MeIQx 0
            N-hydroxy-PhIP 27
            acridine + 28
            arsenic trichloride 40
            benzamidoxime 6
            benzo[a]pyrene-7,8-dione 18
            beryllium dichloride 3
            cadmium nitrate + 3
            cadmium nitrate tetrahydrate 0
            camptothecin 200
            catechol + 1358
            cisplatin 7339
            cobalt(2+) sulfate heptahydrate 0
            colibactin 0
            cylindrospermopsin 515
            ebselen 54
            ethoxyquin 43
            ethyl methanesulfonate 2169
            hydrogen peroxide + 3186
            hydrogen sulfide + 2050
            hydroxyurea 214
            imidacloprid + 84
            methyl methanesulfonate 3641
            mutagen + 16800
            o-anisidine 94
            p-anisidine + 39
            parathion-methyl 50
            riddelliine + 64
            riddelliine N-oxide 0
            tolylfluanid 7
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