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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:insulin-sensitizing drug
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Accession:CHEBI:50864 term browser browse the term
Definition:An agent which overcomes insulin resistance by activation of the peroxisome proliferator activated receptor gamma (PPAR-gamma).
Synonyms:related_synonym: PPAR-gamma agonist;   PPAR-gamma agonists;   PPARgamma agonist;   PPARgamma agonists;   glitazonas;   glitazone drug;   glitazones;   insulin sensitisers;   insulin sensitizers;   insulin-sensitising drug;   insulin-sensitizing agent;   peroxisome proliferator-activated receptor gamma agonist;   peroxisome proliferator-activated receptor gamma agonists;   proliferator activated receptor gamma agonist;   proliferator activated receptor gamma agonists;   thiazolidinediones;   tiazolidinedionas


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15-deoxy-Delta(12,14)-prostaglandin J2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP binding cassette subfamily C member 1 multiple interactions
affects export
affects glutathionylation
increases transport		 ISO [ABCC1 protein results in increased transport of 15-deoxy-delta(12,14)-prostaglandin J2 metabolite] affects the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of GCLC protein]; [verlukast binds to and results in decreased activity of ABCC1 protein] inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of GCLC protein]; ABCC1 protein affects the reaction [15-deoxy-delta(12,14)-prostaglandin J2 promotes the reaction [NFE2L2 protein results in increased expression of GCLC protein]]; ABCC1 protein affects the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of GCLC protein]
ABCC1 protein affects the export of 15-deoxy-delta(12,14)-prostaglandin J2 analog
ABCC1 protein affects the glutathionylation of 15-deoxy-delta(12,14)-prostaglandin J2		 CTD PMID:14979731 PMID:21728338 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114 		JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 affects export ISO ABCC3 protein affects the export of 15-deoxy-delta(12,14)-prostaglandin J2 analog CTD PMID:14979731 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595 		JBrowse link
G Acaa2 acetyl-CoA acyltransferase 2 multiple interactions ISO [15-deoxy-delta(12,14)-prostaglandin J2 co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ACAA2 mRNA CTD PMID:34323617 NCBI chr18:68,345,136...68,373,246
Ensembl chr18:68,345,012...68,373,249 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing multiple interactions ISO [15-deoxy-delta(12,14)-prostaglandin J2 co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ADIPOQ mRNA CTD PMID:34323617 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564 		JBrowse link
G Agt angiotensinogen multiple interactions EXP 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [AGT protein results in decreased expression of PPARG protein]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [AGT protein results in increased expression of and results in increased secretion of SERPINE1 protein]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [AGT protein results in increased expression of SERPINE1 mRNA]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [AGT protein results in increased expression of TGFB1 protein]; 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [AGT protein results in increased expression of and results in increased secretion of SERPINE1 protein]]; 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [AGT protein results in increased expression of SERPINE1 mRNA]]; 2-chloro-5-nitrobenzanilide inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [AGT protein results in increased expression of and results in increased secretion of SERPINE1 protein]]; 2-chloro-5-nitrobenzanilide inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [AGT protein results in increased expression of SERPINE1 mRNA]] CTD PMID:18278065 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977 		JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 multiple interactions ISO [Medroxyprogesterone Acetate inhibits the reaction [[AKR1C3 protein results in increased metabolism of Prostaglandin D2] which results in increased abundance of Dinoprost]] which results in increased abundance of 15-deoxy-delta(12,14)-prostaglandin J2 CTD PMID:19997560 NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO [15-deoxy-delta(12,14)-prostaglandin J2 co-treated with alitretinoin] results in decreased phosphorylation of AKT1 protein CTD PMID:16611854 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Bglap bone gamma-carboxyglutamate protein decreases expression ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of BGLAP mRNA CTD PMID:12021203 NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495 		JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 decreases expression ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of BIRC2 protein CTD PMID:15498850 NCBI chr 8:4,968,856...4,989,325
Ensembl chr 8:4,968,842...4,988,732 		JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 decreases expression ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of BIRC3 protein CTD PMID:15498850 NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802 		JBrowse link
G Casp3 caspase 3 increases activity
multiple interactions
increases cleavage		 ISO
EXP		 15-deoxy-delta(12,14)-prostaglandin J2 results in increased activity of CASP3 protein
[delta(12)-prostaglandin J(2) co-treated with 9-deoxy-delta-9-prostaglandin D2 co-treated with 15-deoxy-delta(12,14)-prostaglandin J2] results in increased cleavage of CASP3 protein
15-deoxy-delta(12,14)-prostaglandin J2 results in increased cleavage of CASP3 protein
15-deoxy-delta(12,14)-prostaglandin J2 results in increased cleavage of and results in increased activity of CASP3 protein		 CTD PMID:11785780 PMID:15498850 PMID:16299251 PMID:23973622 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp8 caspase 8 multiple interactions ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in increased cleavage of and results in increased activity of CASP8 protein CTD PMID:15498850 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Casp9 caspase 9 multiple interactions ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in increased cleavage of and results in increased activity of CASP9 protein CTD PMID:15498850 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Cat catalase multiple interactions ISO CAT protein inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased phosphorylation of STAT1 protein]] CTD PMID:12847270 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [[Dexamethasone binds to NR3C1 protein] which results in decreased expression of CCL2 protein] CTD PMID:15187150 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 multiple interactions ISO 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CCL5 mRNA] CTD PMID:23688403 NCBI chr10:68,322,826...68,327,365
Ensembl chr10:68,322,829...68,327,377 		JBrowse link
G Ccn2 cellular communication network factor 2 multiple interactions ISO 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [TGFB1 protein results in increased expression of and results in increased secretion of CCN2 protein]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [TGFB1 protein results in increased expression of CCN2 mRNA]; SMAD2 protein modified form affects the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [TGFB1 protein results in increased expression of CCN2]] CTD PMID:19429239 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734 		JBrowse link
G Ccna2 cyclin A2 decreases expression ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of CCNA2 protein CTD PMID:15729575 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577 		JBrowse link
G Ccnb1 cyclin B1 decreases expression ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of CCNB1 protein CTD PMID:15729575 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172 		JBrowse link
G Ccnd3 cyclin D3 decreases expression ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of CCND3 protein CTD PMID:15729575 NCBI chr 9:13,394,161...13,400,341
Ensembl chr 9:13,394,169...13,489,371 		JBrowse link
G Ccne1 cyclin E1 decreases expression ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of CCNE1 protein CTD PMID:15729575 NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101 		JBrowse link
G Cdk2 cyclin dependent kinase 2 decreases expression ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of CDK2 protein CTD PMID:15729575 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression
decreases expression		 ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of CDKN1A
15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of CDKN1A protein		 CTD PMID:15254749 PMID:15729575 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B decreases expression ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of CDKN1B protein CTD PMID:15729575 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982 		JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha increases expression ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of CEBPA mRNA CTD PMID:12021203 NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412 		JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator decreases expression ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of CFLAR protein CTD PMID:15498850 NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034 		JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex multiple interactions ISO
EXP		 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of CHUK protein]
15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [manganese chloride results in increased phosphorylation of CHUK protein]		 CTD PMID:15498850 PMID:22245093 NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065 		JBrowse link
G Cidec cell death-inducing DFFA-like effector c multiple interactions ISO [15-deoxy-delta(12,14)-prostaglandin J2 co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of CIDEC mRNA CTD PMID:34323617 NCBI chr 4:146,569,288...146,582,173
Ensembl chr 4:146,569,289...146,582,173 		JBrowse link
G Col1a1 collagen type I alpha 1 chain decreases expression ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of COL1A1 mRNA CTD PMID:12021203 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624 		JBrowse link
G Csf2 colony stimulating factor 2 multiple interactions ISO 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL1B protein results in increased expression of CSF2 mRNA]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL1B protein results in increased expression of CSF2 protein]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [Lipopolysaccharides results in increased expression of CSF2 mRNA]; Dexamethasone promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL1B protein results in increased expression of CSF2 mRNA]] CTD PMID:12604364 PMID:14998300 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199 		JBrowse link
G Ddx58 DEXD/H-box helicase 58 multiple interactions ISO 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [Lipopolysaccharides results in increased expression of DDX58 mRNA] CTD PMID:16303604 NCBI chr 5:55,321,229...55,369,947
Ensembl chr 5:55,321,235...55,370,819 		JBrowse link
G Egr1 early growth response 1 multiple interactions EXP 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [Oxygen deficiency results in increased expression of and results in increased activity of EGR1 protein]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [Oxygen deficiency results in increased expression of EGR1 mRNA] CTD PMID:12468449 NCBI chr18:26,463,333...26,465,531
Ensembl chr18:26,462,981...26,466,766 		JBrowse link
G Fabp4 fatty acid binding protein 4 multiple interactions
increases expression		 ISO [15-deoxy-delta(12,14)-prostaglandin J2 co-treated with Tretinoin] results in increased expression of FABP4 mRNA
[15-deoxy-delta(12,14)-prostaglandin J2 co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of FABP4 mRNA
15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of FABP4 mRNA		 CTD PMID:9543393 PMID:12021203 PMID:16573735 PMID:34323617 NCBI chr 2:91,580,858...91,585,578
Ensembl chr 2:91,580,885...91,585,578 		JBrowse link
G Fas Fas cell surface death receptor decreases expression ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of FAS mRNA CTD PMID:16712844 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression		 ISO
EXP		 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL1B protein results in increased activity of [FOS protein binds to JUN protein]]
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of FOS mRNA]; U 0126 inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of FOS mRNA]; wortmannin inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of FOS mRNA]		 CTD PMID:11457450 PMID:11687581 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions
increases expression		 ISO 15-deoxy-delta(12,14)-prostaglandin J2 promotes the reaction [NFE2L2 protein results in increased expression of GCLC protein]; [ABCC1 protein results in increased transport of 15-deoxy-delta(12,14)-prostaglandin J2 metabolite] affects the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of GCLC protein]; [verlukast binds to and results in decreased activity of ABCC1 protein] inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of GCLC protein]; ABCC1 protein affects the reaction [15-deoxy-delta(12,14)-prostaglandin J2 promotes the reaction [NFE2L2 protein results in increased expression of GCLC protein]]; ABCC1 protein affects the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of GCLC protein]; Acetylcysteine inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of GCLC protein]; NFE2L2 protein affects the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of GCLC protein]
15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of GCLC mRNA; 15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of GCLC protein		 CTD PMID:21728338 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544 		JBrowse link
G Gfap glial fibrillary acidic protein increases expression
decreases expression
multiple interactions		 ISO
EXP		 15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of GFAP
15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of GFAP mRNA
15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [ochratoxin A results in decreased expression of GFAP mRNA]		 CTD PMID:15254749 PMID:15994020 NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589 		JBrowse link
G Gsta3 glutathione S-transferase alpha 3 increases expression ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of GSTA3 mRNA CTD PMID:14652005 NCBI chr 9:23,658,574...23,684,240
Ensembl chr 9:23,658,574...23,684,240 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 multiple interactions ISO GSTM1 protein affects the metabolism of [15-deoxy-delta(12,14)-prostaglandin J2 co-treated with Glutathione] CTD PMID:14979731 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 increases expression
multiple interactions		 EXP 15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of GSTP1 mRNA; 15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of GSTP1 protein
Soybean Oil promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of GSTP1 mRNA]; Soybean Oil promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of GSTP1 protein]		 CTD PMID:11600134 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Hdac1 histone deacetylase 1 decreases expression ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of HDAC1 mRNA CTD PMID:21957481 NCBI chr 5:141,853,992...141,881,057
Ensembl chr 5:141,853,989...141,881,111 		JBrowse link
G Hdac2 histone deacetylase 2 decreases expression ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of HDAC2 mRNA CTD PMID:21957481 NCBI chr20:40,548,250...40,571,609
Ensembl chr20:40,548,250...40,571,609 		JBrowse link
G Hdac3 histone deacetylase 3 decreases expression ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of HDAC3 mRNA CTD PMID:21957481 NCBI chr18:29,770,637...29,789,850
Ensembl chr18:29,770,636...29,793,856 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha affects stability
multiple interactions
increases expression		 ISO 15-deoxy-delta(12,14)-prostaglandin J2 affects the stability of HIF1A protein
Acetylcysteine inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of HIF1A protein]; Buthionine Sulfoximine promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of HIF1A protein]; Dithiothreitol inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of HIF1A protein]; Glutathione inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of HIF1A protein]		 CTD PMID:17658243 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression		 ISO
EXP		 15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of and results in increased activity of HMOX1 protein; [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of and results in increased activity of HMOX1 protein] which results in increased abundance of Iron; [[15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of and results in increased activity of HMOX1 protein] which results in increased abundance of Iron] which results in increased abundance of Reactive Oxygen Species; [[15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of and results in increased activity of HMOX1 protein] which results in increased abundance of Iron] which results in increased expression of MMP1 mRNA; [[[15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of and results in increased activity of HMOX1 protein] which results in increased abundance of Iron] which results in increased abundance of Reactive Oxygen Species] which results in increased expression of MMP1 protein; Acetylcysteine inhibits the reaction [[[[15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of and results in increased activity of HMOX1 protein] which results in increased abundance of Iron] which results in increased abundance of Reactive Oxygen Species] which results in increased expression of MMP1 protein]; HMOX1 protein promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of and results in increased activity of MMP1 protein]; HSF1 protein inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of HMOX1 mRNA]; NFE2L2 protein promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of HMOX1 mRNA]; zinc protoporphyrin inhibits the reaction [[15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of and results in increased activity of HMOX1 protein] which results in increased abundance of Iron]
ochratoxin A inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of HMOX1 mRNA]
15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of HMOX1 mRNA; 15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of HMOX1 protein		 CTD PMID:11078701 PMID:15618017 PMID:15994020 PMID:19136476 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hsf1 heat shock transcription factor 1 multiple interactions
increases activity		 ISO HSF1 protein inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of HMOX1 mRNA]
15-deoxy-delta(12,14)-prostaglandin J2 results in increased activity of HSF1 protein		 CTD PMID:15618017 PMID:34170685 NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011 		JBrowse link
G Hspb1 heat shock protein family B (small) member 1 decreases expression ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of HSPB1 protein CTD PMID:16299251 NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743 		JBrowse link
G Ifng interferon gamma multiple interactions
decreases expression
decreases secretion		 ISO 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [[IFNG protein results in increased expression of NOS2 protein] which results in increased chemical synthesis of Nitric Oxide]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased activity of and results in increased localization of [STAT1 protein binds to STAT1 protein]]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased expression of IRF1 mRNA]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased expression of NOS2 mRNA]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased phosphorylation of and results in increased activity of JAK2 protein]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased phosphorylation of STAT1 protein]; 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in decreased secretion of IFNG protein]; Acetylcysteine inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased phosphorylation of and results in increased activity of JAK2 protein]]; Acetylcysteine inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased phosphorylation of STAT1 protein]]; CAT protein inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased phosphorylation of STAT1 protein]]; Glutathione inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased phosphorylation of and results in increased activity of JAK2 protein]]; Glutathione inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased phosphorylation of STAT1 protein]]; Hydrogen Peroxide promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased phosphorylation of STAT1 protein]]; peroxyvanadate inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased abundance of Nitric Oxide]]; peroxyvanadate inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased phosphorylation of STAT1 protein]]; T 0070907 inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in decreased secretion of IFNG protein]
15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of IFNG protein		 CTD PMID:12847270 PMID:16844232 PMID:19888466 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL1B protein results in increased expression of IL1A mRNA] CTD PMID:14998300 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Il1b interleukin 1 beta multiple interactions
decreases expression
decreases activity		 ISO
EXP		 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL1B protein affects the localization of RELA protein]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL1B protein results in decreased abundance of Prostaglandins]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL1B protein results in increased abundance of Nitric Oxide]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL1B protein results in increased activity of [FOS protein binds to JUN protein]]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL1B protein results in increased activity of [RELA protein binds to NFKB1 protein]]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL1B protein results in increased expression of CSF2 mRNA]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL1B protein results in increased expression of CSF2 protein]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL1B protein results in increased expression of CXCL8 mRNA]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL1B protein results in increased expression of IL1A mRNA]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL1B protein results in increased expression of NOS2 mRNA]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL1B protein results in increased expression of PTGS2 mRNA]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; 15-deoxy-delta(12,14)-prostaglandin J2 promotes the reaction [IL1B protein affects the localization of JUN protein]; Dexamethasone promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL1B protein results in increased expression of CSF2 mRNA]]
15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of IL1B protein
[15-deoxy-delta(12,14)-prostaglandin J2 co-treated with IL1B protein] results in decreased secretion of IL1B protein
15-deoxy-delta(12,14)-prostaglandin J2 results in decreased activity of IL1B protein		 CTD PMID:11457450 PMID:12604364 PMID:14998300 PMID:15751073 PMID:16461118 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il1rn interleukin 1 receptor antagonist decreases expression EXP 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of IL1RN mRNA CTD PMID:15751073 NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445 		JBrowse link
G Il4 interleukin 4 multiple interactions ISO 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased degradation of NFKBIA protein]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CCL5 mRNA]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CXCL8 mRNA]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of 15-deoxy-delta(12,14)-prostaglandin J2]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [butenafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of 15-deoxy-delta(12,14)-prostaglandin J2]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [Itraconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of 15-deoxy-delta(12,14)-prostaglandin J2]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [Ketoconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of 15-deoxy-delta(12,14)-prostaglandin J2]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [luliconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of 15-deoxy-delta(12,14)-prostaglandin J2]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [Terbinafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of 15-deoxy-delta(12,14)-prostaglandin J2]]; [Poly I-C co-treated with IL4 protein] results in decreased secretion of 15-deoxy-delta(12,14)-prostaglandin J2; amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of 15-deoxy-delta(12,14)-prostaglandin J2]; butenafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of 15-deoxy-delta(12,14)-prostaglandin J2]; Itraconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of 15-deoxy-delta(12,14)-prostaglandin J2]; Ketoconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of 15-deoxy-delta(12,14)-prostaglandin J2]; luliconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of 15-deoxy-delta(12,14)-prostaglandin J2]; Terbinafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of 15-deoxy-delta(12,14)-prostaglandin J2] CTD PMID:23688403 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL6 protein results in increased phosphorylation of STAT1 protein]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA] CTD PMID:12604364 PMID:12847270 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Ins2 insulin 2 multiple interactions ISO 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [Fatty Acids, Nonesterified inhibits the reaction [INS protein results in increased secretion of Glucose]]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [Fatty Acids, Nonesterified results in decreased expression of INS mRNA] CTD PMID:14625208 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775 		JBrowse link
G Irf1 interferon regulatory factor 1 multiple interactions ISO 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased expression of IRF1 mRNA] CTD PMID:12847270 NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166 		JBrowse link
G Jak2 Janus kinase 2 multiple interactions ISO 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased phosphorylation of and results in increased activity of JAK2 protein]; Acetylcysteine inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased phosphorylation of and results in increased activity of JAK2 protein]]; Glutathione inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased phosphorylation of and results in increased activity of JAK2 protein]] CTD PMID:12847270 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL1B protein results in increased activity of [FOS protein binds to JUN protein]]; 15-deoxy-delta(12,14)-prostaglandin J2 promotes the reaction [IL1B protein affects the localization of JUN protein] CTD PMID:11457450 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Klf6 Kruppel-like factor 6 multiple interactions ISO [15-deoxy-delta(12,14)-prostaglandin J2 co-treated with alitretinoin] results in decreased phosphorylation of KLF6 protein; RPS6KB1 protein inhibits the reaction [[15-deoxy-delta(12,14)-prostaglandin J2 co-treated with alitretinoin] results in decreased phosphorylation of KLF6 protein] CTD PMID:16611854 NCBI chr17:64,539,456...64,548,451
Ensembl chr17:64,531,463...64,588,570 		JBrowse link
G Lep leptin multiple interactions
increases secretion		 ISO [Dexamethasone co-treated with 15-deoxy-delta(12,14)-prostaglandin J2] results in decreased secretion of LEP protein
15-deoxy-delta(12,14)-prostaglandin J2 results in increased secretion of LEP protein		 CTD PMID:11092516 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262 		JBrowse link
G Lif LIF, interleukin 6 family cytokine multiple interactions ISO 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [LIF protein results in increased expression of STAT3 protein]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [LIF protein results in increased phosphorylation of STAT3 protein]; 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [LIF protein results in increased expression of STAT3 protein]]; 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [LIF protein results in increased phosphorylation of STAT3 protein]]; T 0070907 inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [LIF protein results in increased expression of STAT3 protein]]; T 0070907 inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [LIF protein results in increased phosphorylation of STAT3 protein]] CTD PMID:19922793 NCBI chr14:79,131,049...79,140,486
Ensembl chr14:79,134,574...79,140,482 		JBrowse link
G Lpl lipoprotein lipase increases expression ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of LPL mRNA CTD PMID:12021203 NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 decreases phosphorylation
multiple interactions
increases phosphorylation		 ISO
EXP		 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased phosphorylation of MAPK1 protein
15-deoxy-delta(12,14)-prostaglandin J2 results in increased phosphorylation of and results in increased activity of MAPK1 protein; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased phosphorylation of and results in increased activity of MAPK1 protein]; U 0126 inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased phosphorylation of and results in increased activity of MAPK1 protein]
15-deoxy-delta(12,14)-prostaglandin J2 results in increased phosphorylation of MAPK1 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased phosphorylation of MAPK1 protein]; [15-deoxy-delta(12,14)-prostaglandin J2 co-treated with alitretinoin] results in decreased phosphorylation of MAPK1 protein; Glutathione inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased phosphorylation of MAPK1 protein]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased phosphorylation of MAPK1 protein]		 CTD PMID:11687581 PMID:12083801 PMID:16611854 PMID:19888466 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 decreases phosphorylation
multiple interactions
increases phosphorylation		 ISO
EXP		 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased phosphorylation of MAPK3 protein
15-deoxy-delta(12,14)-prostaglandin J2 results in increased phosphorylation of and results in increased activity of MAPK3 protein; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased phosphorylation of and results in increased activity of MAPK3 protein]; U 0126 inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased phosphorylation of and results in increased activity of MAPK3 protein]
15-deoxy-delta(12,14)-prostaglandin J2 results in increased phosphorylation of MAPK3 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased phosphorylation of MAPK3 protein]; [15-deoxy-delta(12,14)-prostaglandin J2 co-treated with alitretinoin] results in decreased phosphorylation of MAPK3 protein; Glutathione inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased phosphorylation of MAPK3 protein]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased phosphorylation of MAPK3 protein]		 CTD PMID:11687581 PMID:12083801 PMID:16611854 PMID:19888466 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Med1 mediator complex subunit 1 multiple interactions ISO MED1 protein promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased activity of PPARG protein] CTD PMID:16324150 NCBI chr10:83,145,538...83,189,260
Ensembl chr10:83,145,568...83,189,299 		JBrowse link
G Mmp1 matrix metallopeptidase 1 multiple interactions
increases expression		 ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of and results in increased activity of MMP1 protein; [[15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of and results in increased activity of HMOX1 protein] which results in increased abundance of Iron] which results in increased expression of MMP1 mRNA; [[[15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of and results in increased activity of HMOX1 protein] which results in increased abundance of Iron] which results in increased abundance of Reactive Oxygen Species] which results in increased expression of MMP1 protein; Acetylcysteine inhibits the reaction [[[[15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of and results in increased activity of HMOX1 protein] which results in increased abundance of Iron] which results in increased abundance of Reactive Oxygen Species] which results in increased expression of MMP1 protein]; Cycloheximide inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of MMP1 protein]; Dactinomycin inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of MMP1 protein]; Deferoxamine inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of MMP1 mRNA]; Deferoxamine inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of MMP1 protein]; HMOX1 protein promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of and results in increased activity of MMP1 protein]; NFE2L2 protein promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of MMP1 mRNA] CTD PMID:19136476 NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097 		JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
decreases expression		 ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased activity of and results in decreased expression of MMP9 protein; 2-chloro-5-nitrobenzanilide inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in decreased activity of and results in decreased expression of MMP9 protein]; 2-chloro-5-nitrobenzanilide inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of MMP9 mRNA] CTD PMID:19997048 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Mtor mechanistic target of rapamycin kinase multiple interactions ISO [15-deoxy-delta(12,14)-prostaglandin J2 co-treated with alitretinoin] results in decreased phosphorylation of MTOR protein CTD PMID:16611854 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311 		JBrowse link
G Nes nestin increases expression EXP 15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of NES protein CTD PMID:15212945 NCBI chr 2:173,437,867...173,447,777
Ensembl chr 2:173,438,734...173,447,777 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions ISO
EXP		 15-deoxy-delta(12,14)-prostaglandin J2 affects the localization of and results in increased activity of NFE2L2 protein; 15-deoxy-delta(12,14)-prostaglandin J2 promotes the reaction [NFE2L2 protein results in increased expression of GCLC protein]; ABCC1 protein affects the reaction [15-deoxy-delta(12,14)-prostaglandin J2 promotes the reaction [NFE2L2 protein results in increased expression of GCLC protein]]; Acetylcysteine inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased activity of NFE2L2 protein]; NFE2L2 protein affects the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of GCLC protein]; NFE2L2 protein promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of HMOX1 mRNA]; NFE2L2 protein promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of MMP1 mRNA]
15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of and affects the localization of NFE2L2 protein; manganese chloride inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of NFE2L2 protein]		 CTD PMID:19136476 PMID:21728338 PMID:22245093 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions
decreases localization		 ISO 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL1B protein results in increased activity of [RELA protein binds to NFKB1 protein]]
15-deoxy-delta(12,14)-prostaglandin J2 results in decreased localization of NFKB1 protein		 CTD PMID:11457450 PMID:16299251 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404 		JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions
decreases phosphorylation		 ISO
EXP		 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased degradation of NFKBIA protein]
15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [manganese chloride results in increased degradation of NFKBIA protein]
15-deoxy-delta(12,14)-prostaglandin J2 results in decreased phosphorylation of NFKBIA protein		 CTD PMID:15498850 PMID:22245093 PMID:23688403 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
decreases activity
decreases expression		 ISO
EXP		 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL1B protein results in increased expression of NOS2 mRNA]
15-deoxy-delta(12,14)-prostaglandin J2 results in decreased activity of NOS2 protein
15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [ochratoxin A results in increased expression of NOS2 mRNA]; 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased activity of and results in decreased expression of NOS2 protein
15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of NOS2 mRNA
15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [[IFNG protein results in increased expression of NOS2 protein] which results in increased chemical synthesis of Nitric Oxide]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [Bleomycin results in increased expression of NOS2 protein]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased expression of NOS2 mRNA]; 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased activity of and results in decreased expression of NOS2 protein; 2-chloro-5-nitrobenzanilide inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in decreased activity of and results in decreased expression of NOS2 protein]; 2-chloro-5-nitrobenzanilide inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of NOS2 mRNA]		 CTD PMID:11457450 PMID:11890746 PMID:12847270 PMID:15684285 PMID:15994020 More... NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Nos3 nitric oxide synthase 3 decreases activity EXP 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased activity of NOS3 protein CTD PMID:11890746 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 affects activity
multiple interactions		 ISO 15-deoxy-delta(12,14)-prostaglandin J2 affects the activity of NR3C1 protein
15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [[Dexamethasone binds to NR3C1 protein] which results in decreased expression of CCL2 protein]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [Dexamethasone binds to NR3C1 protein]		 CTD PMID:15187150 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375 		JBrowse link
G Park7 Parkinsonism associated deglycase multiple interactions EXP 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [manganese chloride results in decreased expression of PARK7 mRNA]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [manganese chloride results in decreased expression of PARK7 protein] CTD PMID:22245093 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage
multiple interactions		 ISO
EXP		 15-deoxy-delta(12,14)-prostaglandin J2 results in increased cleavage of PARP1 protein
[delta(12)-prostaglandin J(2) co-treated with 9-deoxy-delta-9-prostaglandin D2 co-treated with 15-deoxy-delta(12,14)-prostaglandin J2] results in increased cleavage of PARP1 protein		 CTD PMID:15498850 PMID:23973622 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 increases expression ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of PCK1 mRNA CTD PMID:9518257 NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191 		JBrowse link
G Plin1 perilipin 1 multiple interactions ISO [15-deoxy-delta(12,14)-prostaglandin J2 co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of PLIN1 mRNA CTD PMID:34323617 NCBI chr 1:133,664,294...133,676,854
Ensembl chr 1:133,664,892...133,676,828 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO 15-deoxy-delta(12,14)-prostaglandin J2 binds to and results in increased activity of PPARA protein
[15-deoxy-delta(12,14)-prostaglandin J2 co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of PPARA mRNA		 CTD PMID:9013583 PMID:34323617 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
G Ppard peroxisome proliferator-activated receptor delta increases expression ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of PPARD protein CTD PMID:17341418 NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma affects expression
decreases response to substance
increases expression
increases activity
multiple interactions
decreases expression		 ISO
EXP		 15-deoxy-delta(12,14)-prostaglandin J2 affects the expression of PPARG
PPARG protein mutant form results in decreased susceptibility to 15-deoxy-delta(12,14)-prostaglandin J2
15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of PPARG mRNA; 15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of PPARG protein
15-deoxy-delta(12,14)-prostaglandin J2 results in increased activity of PPARG protein
15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [AGT protein results in decreased expression of PPARG protein]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [ochratoxin A results in increased expression of PPARG mRNA]
15-deoxy-delta(12,14)-prostaglandin J2 binds to and results in increased activity of PPARG protein; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [PPARG protein affects the reaction [Lipopolysaccharides results in increased abundance of Nitric Oxide]]; MED1 protein promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased activity of PPARG protein]
15-deoxy-delta(12,14)-prostaglandin J2 affects the localization of and results in increased expression of PPARG protein; 15-deoxy-delta(12,14)-prostaglandin J2 binds to and results in decreased activity of PPARG protein; 15-deoxy-delta(12,14)-prostaglandin J2 binds to and results in increased activity of PPARG protein; 15-deoxy-delta(12,14)-prostaglandin J2 binds to and results in increased localization of and results in increased activity of PPARG protein; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [deoxynivalenol results in increased expression of PPARG protein]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [Fatty Acids, Nonesterified results in decreased expression of PPARG mRNA]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [Lipopolysaccharides results in decreased expression of PPARG mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased activity of PPARG protein]; MG 262 promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased activity of PPARG protein]; PPARG protein affects the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of TBXA2R mRNA alternative form]
15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of PPARG protein		 CTD PMID:9013583 PMID:10662598 PMID:11030710 PMID:12065695 PMID:12604364 More... NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Pten phosphatase and tensin homolog multiple interactions ISO [15-deoxy-delta(12,14)-prostaglandin J2 co-treated with alitretinoin] results in increased expression of PTEN protein CTD PMID:16611854 NCBI chr 1:230,631,303...230,696,754
Ensembl chr 1:230,630,338...230,696,838 		JBrowse link
G Ptgdr prostaglandin D2 receptor multiple interactions ISO 15-deoxy-delta(12,14)-prostaglandin J2 binds to and results in increased activity of PTGDR protein; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [Prostaglandin D2 binds to PTGDR protein] CTD PMID:9579725 NCBI chr15:17,360,304...17,367,679
Ensembl chr15:17,360,304...17,367,679 		JBrowse link
G Ptgdr2 prostaglandin D2 receptor 2 multiple interactions ISO 15-deoxy-delta(12,14)-prostaglandin J2 binds to and results in increased activity of PTGDR2 protein; ramatroban inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 binds to and results in increased activity of PTGDR2 protein]
15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [Prostaglandin D2 binds to PTGDR2 protein]		 CTD PMID:12721327 PMID:16256979 NCBI chr 1:207,585,088...207,590,275
Ensembl chr 1:207,587,917...207,589,213 		JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 multiple interactions ISO PTGS1 protein promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased abundance of 15-deoxy-delta(12,14)-prostaglandin J2] CTD PMID:17439952 NCBI chr 3:19,584,015...19,605,589
Ensembl chr 3:19,584,015...19,605,586 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
decreases expression
increases expression		 ISO 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL1B protein results in increased expression of PTGS2 mRNA]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]
15-deoxy-delta(12,14)-prostaglandin J2 results in decreased activity of and results in decreased expression of PTGS2 protein; 2-chloro-5-nitrobenzanilide inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in decreased activity of and results in decreased expression of PTGS2 protein]; 2-chloro-5-nitrobenzanilide inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of PTGS2 mRNA]
15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of PTGS2		 CTD PMID:11457450 PMID:12604364 PMID:15254749 PMID:19997048 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 increases phosphorylation EXP 15-deoxy-delta(12,14)-prostaglandin J2 results in increased phosphorylation of PTPN11 protein CTD PMID:12584205 NCBI chr12:35,365,436...35,424,925
Ensembl chr12:35,383,144...35,424,925 		JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase multiple interactions ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in increased activity of and results in decreased phosphorylation of RAF1 protein CTD PMID:12083801 NCBI chr 4:148,679,534...148,740,265
Ensembl chr 4:148,679,530...148,740,317 		JBrowse link
G Rarb retinoic acid receptor, beta multiple interactions
increases expression		 ISO 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [ciglitazone promotes the reaction [SR 11237 results in increased expression of RARB protein]]
15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of RARB		 CTD PMID:12839938 PMID:15254749 NCBI chr15:8,700,533...9,051,288
Ensembl chr15:8,406,492...9,051,288 		JBrowse link
G Rb1 RB transcriptional corepressor 1 multiple interactions ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased phosphorylation of and results in decreased expression of RB1 protein CTD PMID:15729575 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
decreases activity		 ISO
EXP		 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL1B protein affects the localization of RELA protein]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL1B protein results in increased activity of [RELA protein binds to NFKB1 protein]]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [Lipopolysaccharides results in increased activity of RELA protein]
15-deoxy-delta(12,14)-prostaglandin J2 results in decreased activity of RELA protein
15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [manganese chloride affects the localization of RELA protein]		 CTD PMID:11457450 PMID:15498850 PMID:20174873 PMID:22245093 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Rps6ka1 ribosomal protein S6 kinase A1 multiple interactions ISO [15-deoxy-delta(12,14)-prostaglandin J2 co-treated with alitretinoin] results in decreased phosphorylation of RPS6KA1 protein CTD PMID:16611854 NCBI chr 5:146,079,018...146,118,272
Ensembl chr 5:146,079,021...146,118,272 		JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 multiple interactions ISO [15-deoxy-delta(12,14)-prostaglandin J2 co-treated with alitretinoin] results in decreased phosphorylation of and results in decreased activity of RPS6KB1 protein; RPS6KB1 protein inhibits the reaction [[15-deoxy-delta(12,14)-prostaglandin J2 co-treated with alitretinoin] results in decreased expression of TGFB1 mRNA]; RPS6KB1 protein inhibits the reaction [[15-deoxy-delta(12,14)-prostaglandin J2 co-treated with alitretinoin] results in decreased phosphorylation of KLF6 protein] CTD PMID:16611854 NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908 		JBrowse link
G Runx2 RUNX family transcription factor 2 decreases expression ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of RUNX2 mRNA CTD PMID:12021203 NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167 		JBrowse link
G Rxra retinoid X receptor alpha increases expression ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of RXRA CTD PMID:15254749 NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712 		JBrowse link
G Serpine1 serpin family E member 1 multiple interactions EXP 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [AGT protein results in increased expression of and results in increased secretion of SERPINE1 protein]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [AGT protein results in increased expression of SERPINE1 mRNA]; 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [AGT protein results in increased expression of and results in increased secretion of SERPINE1 protein]]; 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [AGT protein results in increased expression of SERPINE1 mRNA]]; 2-chloro-5-nitrobenzanilide inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [AGT protein results in increased expression of and results in increased secretion of SERPINE1 protein]]; 2-chloro-5-nitrobenzanilide inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [AGT protein results in increased expression of SERPINE1 mRNA]] CTD PMID:18278065 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657 		JBrowse link
G Smad2 SMAD family member 2 multiple interactions ISO 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD2 protein]; SMAD2 protein modified form affects the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [TGFB1 protein results in increased expression of CCN2]] CTD PMID:19429239 NCBI chr18:69,849,884...69,918,926
Ensembl chr18:69,850,377...69,912,323 		JBrowse link
G Socs1 suppressor of cytokine signaling 1 increases expression EXP 15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of SOCS1 mRNA CTD PMID:12584205 NCBI chr10:4,882,651...4,884,342
Ensembl chr10:4,882,560...4,884,383 		JBrowse link
G Socs3 suppressor of cytokine signaling 3 increases expression EXP 15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of SOCS3 mRNA CTD PMID:12584205 NCBI chr10:103,193,909...103,197,322
Ensembl chr10:103,193,537...103,197,787 		JBrowse link
G Spp1 secreted phosphoprotein 1 decreases expression ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of SPP1 mRNA CTD PMID:12021203 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162 		JBrowse link
G Stat1 signal transducer and activator of transcription 1 multiple interactions ISO
EXP		 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL6 protein results in increased phosphorylation of STAT1 protein]
15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of STAT1 protein]
15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased activity of and results in increased localization of [STAT1 protein binds to STAT1 protein]]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased phosphorylation of STAT1 protein]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [peroxyvanadate results in increased phosphorylation of STAT1 protein]; Acetylcysteine inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased phosphorylation of STAT1 protein]]; CAT protein inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased phosphorylation of STAT1 protein]]; Glutathione inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased phosphorylation of STAT1 protein]]; Hydrogen Peroxide promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased phosphorylation of STAT1 protein]]; peroxyvanadate inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased phosphorylation of STAT1 protein]]		 CTD PMID:12584205 PMID:12847270 NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO
EXP		 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [LIF protein results in increased expression of STAT3 protein]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [LIF protein results in increased phosphorylation of STAT3 protein]; 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [LIF protein results in increased expression of STAT3 protein]]; 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [LIF protein results in increased phosphorylation of STAT3 protein]]; T 0070907 inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [LIF protein results in increased expression of STAT3 protein]]; T 0070907 inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [LIF protein results in increased phosphorylation of STAT3 protein]]
15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of STAT3 protein]
15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein]		 CTD PMID:12584205 PMID:12847270 PMID:19922793 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
G Tbxa2r thromboxane A2 receptor multiple interactions
decreases expression		 ISO PPARG protein affects the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of TBXA2R mRNA alternative form] CTD PMID:16499875 NCBI chr 7:8,383,347...8,390,753
Ensembl chr 7:8,383,378...8,388,176 		JBrowse link
G Tg thyroglobulin multiple interactions
increases expression		 ISO 15-deoxy-delta(12,14)-prostaglandin J2 promotes the reaction [TSHB protein results in increased expression of TG protein]
15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of TG protein		 CTD PMID:11078701 NCBI chr 7:98,418,293...98,603,210
Ensembl chr 7:98,418,293...98,603,210 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions
decreases expression
decreases response to substance		 ISO
EXP		 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [TGFB1 protein results in increased expression of and results in increased secretion of CCN2 protein]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [TGFB1 protein results in increased expression of CCN2 mRNA]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD2 protein]; SMAD2 protein modified form affects the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [TGFB1 protein results in increased expression of CCN2]]
15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of TGFB1 mRNA
15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [AGT protein results in increased expression of TGFB1 protein]
15-deoxy-delta(12,14)-prostaglandin J2 promotes the reaction [alitretinoin results in decreased expression of TGFB1 mRNA]; 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [[alitretinoin co-treated with 15-deoxy-delta(12,14)-prostaglandin J2] results in decreased expression of TGFB1 mRNA]; 2-chloro-5-nitrobenzanilide inhibits the reaction [[alitretinoin co-treated with 15-deoxy-delta(12,14)-prostaglandin J2] results in decreased expression of TGFB1 mRNA]; RPS6KB1 protein inhibits the reaction [[15-deoxy-delta(12,14)-prostaglandin J2 co-treated with alitretinoin] results in decreased expression of TGFB1 mRNA]
15-deoxy-delta(12,14)-prostaglandin J2 results in decreased susceptibility to TGFB1 protein		 CTD PMID:16611854 PMID:18278065 PMID:19429239 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Th tyrosine hydroxylase increases expression EXP 15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of TH protein CTD PMID:15212945 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767 		JBrowse link
G Tlr2 toll-like receptor 2 multiple interactions
decreases expression		 ISO 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [Lipopolysaccharides results in increased expression of TLR2 mRNA]
15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of TLR2 mRNA		 CTD PMID:20174873 NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630 		JBrowse link
G Tnf tumor necrosis factor decreases expression
multiple interactions		 ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of TNF protein
15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]		 CTD PMID:12604364 PMID:19888466 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tshb thyroid stimulating hormone subunit beta multiple interactions ISO 15-deoxy-delta(12,14)-prostaglandin J2 promotes the reaction [TSHB protein results in increased expression of TG protein] CTD PMID:11078701 NCBI chr 2:190,224,676...190,229,559
Ensembl chr 2:190,224,676...190,229,559 		JBrowse link
G Tslp thymic stromal lymphopoietin multiple interactions ISO 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein] CTD PMID:23688403 NCBI chr18:24,447,409...24,454,244
Ensembl chr18:24,449,844...24,453,548 		JBrowse link
G Vim vimentin decreases expression ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of VIM CTD PMID:15254749 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187 		JBrowse link
G Wnt10b Wnt family member 10B decreases expression ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of WNT10B mRNA CTD PMID:12021203 NCBI chr 7:129,922,088...129,927,892
Ensembl chr 7:129,922,088...129,927,892 		JBrowse link
G Xiap X-linked inhibitor of apoptosis decreases expression ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of XIAP protein CTD PMID:15498850 PMID:16299251 NCBI chr  X:120,890,537...120,938,413
Ensembl chr  X:120,897,907...120,934,700 		JBrowse link
bixin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nfe2l2 NFE2 like bZIP transcription factor 2 decreases ubiquitination ISO bixin results in decreased ubiquitination of NFE2L2 protein CTD PMID:30698894 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
ciglitazone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 decreases activity ISO ciglitazone results in decreased activity of ABCB11 protein CTD PMID:20829430 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730 		JBrowse link
G Abhd3 abhydrolase domain containing 3, phospholipase multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of ABHD3 mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of ABHD3 mRNA CTD PMID:16197558 NCBI chr18:1,723,203...1,778,488
Ensembl chr18:1,720,718...1,803,428 		JBrowse link
G Acaa1a acetyl-CoA acyltransferase 1A multiple interactions ISO [ciglitazone binds to PPARG protein] which results in increased expression of ACAA1 mRNA CTD PMID:16197558 NCBI chr 8:119,079,401...119,088,624
Ensembl chr 8:119,079,775...119,088,624 		JBrowse link
G Acaa2 acetyl-CoA acyltransferase 2 multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of ACAA2 mRNA CTD PMID:16197558 NCBI chr18:68,345,136...68,373,246
Ensembl chr18:68,345,012...68,373,249 		JBrowse link
G Acadm acyl-CoA dehydrogenase medium chain multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of ACADM mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of ACADM mRNA CTD PMID:16197558 NCBI chr 2:242,858,865...242,883,036
Ensembl chr 2:242,858,865...242,883,147 		JBrowse link
G Acadvl acyl-CoA dehydrogenase, very long chain multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of ACADVL mRNA CTD PMID:16197558 NCBI chr10:54,732,875...54,738,102
Ensembl chr10:54,732,469...54,738,075 		JBrowse link
G Acsl1 acyl-CoA synthetase long-chain family member 1 multiple interactions ISO [ciglitazone binds to PPARG protein] which results in increased expression of ACSL1 mRNA CTD PMID:16197558 NCBI chr16:45,755,246...45,821,541
Ensembl chr16:45,755,254...45,821,541 		JBrowse link
G Acsm3 acyl-CoA synthetase medium-chain family member 3 multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of ACSM3 mRNA CTD PMID:16197558 NCBI chr 1:174,133,260...174,159,966
Ensembl chr 1:174,133,288...174,160,184 		JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions ISO ciglitazone inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 mRNA] CTD PMID:18162602 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554 		JBrowse link
G Agpat2 1-acylglycerol-3-phosphate O-acyltransferase 2 increases expression ISO ciglitazone results in increased expression of AGPAT2 mRNA CTD PMID:16847310 NCBI chr 3:9,416,842...9,428,567
Ensembl chr 3:9,416,843...9,428,371 		JBrowse link
G Agt angiotensinogen decreases response to substance EXP ciglitazone results in decreased susceptibility to AGT protein modified form CTD PMID:16820301 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977 		JBrowse link
G Akap2 A-kinase anchoring protein 2 multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of PALM2AKAP2 mRNA CTD PMID:16197558 NCBI chr 5:72,536,986...72,648,524
Ensembl chr 5:72,181,718...72,648,524 		JBrowse link
G Akr1c1 aldo-keto reductase family 1, member C1 multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of AKR1C1 mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of AKR1C1 mRNA CTD PMID:16197558 NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326 		JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of AKR1C2 mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of AKR1C2 mRNA CTD PMID:16197558 NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764 		JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 decreases expression EXP ciglitazone results in decreased expression of ALDH1A1 mRNA CTD PMID:22193206 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961 		JBrowse link
G Ang angiogenin multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of ANG mRNA CTD PMID:16197558 NCBI chr15:24,317,733...24,323,361 JBrowse link
G Angptl4 angiopoietin-like 4 multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of ANGPTL4 mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of ANGPTL4 mRNA CTD PMID:16197558 NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519 		JBrowse link
G Apom apolipoprotein M multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of APOM mRNA CTD PMID:16197558 NCBI chr20:3,690,950...3,693,550
Ensembl chr20:3,688,413...3,693,550 		JBrowse link
G Aqp1 aquaporin 1 decreases expression EXP ciglitazone results in decreased expression of AQP1 mRNA CTD PMID:22193206 NCBI chr 4:84,482,512...84,494,690
Ensembl chr 4:84,482,512...84,494,690 		JBrowse link
G Aqp3 aquaporin 3 (Gill blood group) multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of AQP3 mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of AQP3 mRNA CTD PMID:16197558 NCBI chr 5:56,239,200...56,244,718
Ensembl chr 5:56,239,201...56,244,720 		JBrowse link
G Arhgef2 Rho/Rac guanine nucleotide exchange factor 2 multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of ARHGEF2 mRNA CTD PMID:16197558 NCBI chr 2:174,061,126...174,118,355
Ensembl chr 2:174,062,976...174,118,355 		JBrowse link
G Atf7ip2 activating transcription factor 7 interacting protein 2 multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of ATF7IP2 mRNA CTD PMID:16197558 NCBI chr10:5,403,099...5,445,989
Ensembl chr10:5,403,105...5,446,142 		JBrowse link
G Atp1b1 ATPase Na+/K+ transporting subunit beta 1 decreases expression EXP ciglitazone results in decreased expression of ATP1B1 mRNA CTD PMID:22193206 NCBI chr13:76,786,580...76,807,096
Ensembl chr13:76,786,578...76,807,459 		JBrowse link
G Atp1b3 ATPase Na+/K+ transporting subunit beta 3 decreases expression EXP ciglitazone results in decreased expression of ATP1B3 mRNA CTD PMID:22193206 NCBI chr 8:96,910,265...96,941,592
Ensembl chr 8:96,910,309...96,941,598 		JBrowse link
G Bad BCL2-associated agonist of cell death increases expression EXP ciglitazone results in increased expression of BAD protein CTD PMID:12065618 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
affects response to substance
increases expression		 ISO
EXP		 [Niflumic Acid co-treated with ciglitazone] results in increased activity of BAX protein; DDIT3 mutant form inhibits the reaction [[Niflumic Acid co-treated with ciglitazone] results in increased activity of BAX protein]
BAX mRNA affects the susceptibility to ciglitazone
ciglitazone results in increased expression of BAX protein		 CTD PMID:12065618 PMID:15492468 PMID:21067863 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO ciglitazone results in decreased expression of BCL2 protein CTD PMID:15492468 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bcl6 BCL6, transcription repressor multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of BCL6 mRNA CTD PMID:16197558 NCBI chr11:76,854,090...76,877,389
Ensembl chr11:76,854,090...76,877,389 		JBrowse link
G Bdh1 3-hydroxybutyrate dehydrogenase 1 multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of BDH1 mRNA CTD PMID:16197558 NCBI chr11:69,302,534...69,343,173
Ensembl chr11:69,302,534...69,337,671 		JBrowse link
G Bhmt betaine-homocysteine S-methyltransferase multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of BHMT mRNA CTD PMID:16197558 NCBI chr 2:24,859,871...24,879,449
Ensembl chr 2:24,859,873...24,879,742 		JBrowse link
G Bid BH3 interacting domain death agonist multiple interactions ISO [Niflumic Acid co-treated with ciglitazone] results in increased cleavage of BID protein; DDIT3 mutant form inhibits the reaction [[Niflumic Acid co-treated with ciglitazone] results in increased cleavage of BID protein] CTD PMID:21067863 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases expression ISO ciglitazone results in decreased expression of BIRC5 CTD PMID:17940898 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380 		JBrowse link
G Blvrb biliverdin reductase B multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of BLVRB mRNA CTD PMID:16197558 NCBI chr 1:82,738,646...82,756,312
Ensembl chr 1:82,738,695...82,770,375 		JBrowse link
G Cadm1 cell adhesion molecule 1 decreases expression EXP ciglitazone results in decreased expression of CADM1 mRNA CTD PMID:22193206 NCBI chr 8:47,847,836...48,178,703
Ensembl chr 8:47,847,325...48,182,833 		JBrowse link
G Casp3 caspase 3 multiple interactions
increases expression		 ISO [Niflumic Acid co-treated with ciglitazone] results in increased cleavage of CASP3 protein; benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [[Niflumic Acid co-treated with ciglitazone] results in increased cleavage of CASP3 protein]; DDIT3 mutant form inhibits the reaction [[Niflumic Acid co-treated with ciglitazone] results in increased cleavage of CASP3 protein]; GAST protein inhibits the reaction [ciglitazone results in increased expression of CASP3 mRNA] CTD PMID:15387324 PMID:21067863 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp8 caspase 8 multiple interactions
increases activity		 ISO benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [ciglitazone promotes the reaction [Niflumic Acid results in increased activity of CASP8 protein]]; benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [Niflumic Acid promotes the reaction [ciglitazone results in increased activity of CASP8 protein]]; ciglitazone promotes the reaction [Niflumic Acid results in increased activity of CASP8 protein]; DDIT3 mutant form inhibits the reaction [ciglitazone promotes the reaction [Niflumic Acid results in increased activity of CASP8 protein]]; DDIT3 mutant form inhibits the reaction [Niflumic Acid promotes the reaction [ciglitazone results in increased activity of CASP8 protein]]; Niflumic Acid promotes the reaction [ciglitazone results in increased activity of CASP8 protein] CTD PMID:21067863 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Casp9 caspase 9 multiple interactions ISO [Niflumic Acid co-treated with ciglitazone] results in increased cleavage of CASP9 protein; benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [[Niflumic Acid co-treated with ciglitazone] results in increased cleavage of CASP9 protein]; DDIT3 mutant form inhibits the reaction [[Niflumic Acid co-treated with ciglitazone] results in increased cleavage of CASP9 protein] CTD PMID:21067863 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Cat catalase multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of CAT mRNA CTD PMID:16197558 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Ccl20 C-C motif chemokine ligand 20 multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of CCL20 mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of CCL20 mRNA CTD PMID:16197558 NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 multiple interactions ISO ciglitazone inhibits the reaction [Thioglycolates results in increased secretion of CCL5 protein] CTD PMID:12624547 NCBI chr10:68,322,826...68,327,365
Ensembl chr10:68,322,829...68,327,377 		JBrowse link
G Ccl9 chemokine (C-C motif) ligand 9 multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of CCL15 mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of CCL15 mRNA CTD PMID:16197558 NCBI chr10:68,366,486...68,371,408
Ensembl chr10:68,366,487...68,371,369 		JBrowse link
G Ccna2 cyclin A2 decreases expression ISO ciglitazone results in decreased expression of CCNA2 protein CTD PMID:21080969 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577 		JBrowse link
G Ccnd1 cyclin D1 decreases expression
increases expression		 ISO
EXP		 ciglitazone results in decreased expression of CCND1
ciglitazone results in increased expression of CCND1 mRNA
ciglitazone results in decreased expression of CCND1 protein		 CTD PMID:12787395 PMID:18162602 PMID:20578043 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Cdh1 cadherin 1 multiple interactions
decreases expression		 ISO
EXP		 [ciglitazone binds to PPARG protein alternative form] which results in increased expression of CDH1 mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of CDH1 mRNA; ciglitazone results in increased expression of and results in increased activity of CDH1 protein
ciglitazone results in decreased expression of CDH1 mRNA		 CTD PMID:12391285 PMID:16197558 PMID:22193206 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775 		JBrowse link
G Cdk1 cyclin-dependent kinase 1 decreases expression
multiple interactions		 ISO ciglitazone results in decreased expression of CDK1 protein
CREBBP protein inhibits the reaction [ciglitazone results in decreased expression of CDK1 protein]; NCOA1 protein inhibits the reaction [ciglitazone results in decreased expression of CDK1 protein]		 CTD PMID:21080969 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408 		JBrowse link
G Cdk4 cyclin-dependent kinase 4 decreases expression
multiple interactions		 ISO
EXP		 ciglitazone results in decreased expression of CDK4 protein
ciglitazone results in decreased expression of CDK4 mRNA
CREBBP protein inhibits the reaction [ciglitazone results in decreased expression of CDK4 protein]; NCOA1 protein inhibits the reaction [ciglitazone results in decreased expression of CDK4 protein]		 CTD PMID:20578043 PMID:21080969 NCBI chr 7:62,885,647...62,889,562
Ensembl chr 7:62,883,105...62,942,403 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A decreases expression
increases expression		 ISO ciglitazone results in decreased expression of CDKN1A
ciglitazone results in increased expression of CDKN1A protein		 CTD PMID:12787395 PMID:19140230 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases expression EXP ciglitazone results in increased expression of CDKN1B mRNA CTD PMID:20578043 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982 		JBrowse link
G Cebpb CCAAT/enhancer binding protein beta increases expression EXP ciglitazone results in increased expression of CEBPB mRNA CTD PMID:22193206 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473 		JBrowse link
G Cebpd CCAAT/enhancer binding protein delta multiple interactions ISO [ciglitazone binds to PPARG protein] which results in increased expression of CEBPD mRNA CTD PMID:16197558 NCBI chr11:84,764,670...84,765,808
Ensembl chr11:84,764,565...84,765,829 		JBrowse link
G Ces1d carboxylesterase 1D decreases expression ISO ciglitazone results in decreased expression of CES1 mRNA CTD PMID:11409902 NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035 		JBrowse link
G Chmp5 charged multivesicular body protein 5 multiple interactions ISO [ciglitazone binds to PPARG protein] which results in increased expression of CHMP5 mRNA CTD PMID:16197558 NCBI chr 5:56,081,385...56,098,529
Ensembl chr 5:56,081,343...56,098,529 		JBrowse link
G Cidec cell death-inducing DFFA-like effector c multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of CIDEC mRNA CTD PMID:16197558 NCBI chr 4:146,569,288...146,582,173
Ensembl chr 4:146,569,289...146,582,173 		JBrowse link
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 multiple interactions ISO [ciglitazone binds to PPARG protein] which results in increased expression of CITED2 mRNA CTD PMID:16197558 NCBI chr 1:12,312,426...12,314,869
Ensembl chr 1:12,312,160...12,314,897 		JBrowse link
G Cobll1 cordon-bleu WH2 repeat protein-like 1 multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of COBLL1 mRNA CTD PMID:16197558 NCBI chr 3:49,753,260...49,915,168
Ensembl chr 3:49,753,262...49,915,194 		JBrowse link
G Col10a1 collagen type X alpha 1 chain multiple interactions EXP ciglitazone inhibits the reaction [Triiodothyronine results in increased expression of COL10A1 mRNA] CTD PMID:16023420 NCBI chr20:38,183,103...38,189,488
Ensembl chr20:38,182,494...38,189,494 		JBrowse link
G Col11a1 collagen type XI alpha 1 chain decreases expression EXP ciglitazone results in decreased expression of COL11A1 mRNA CTD PMID:22193206 NCBI chr 2:201,820,715...202,013,853
Ensembl chr 2:201,820,715...202,013,853 		JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions ISO ciglitazone inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA] CTD PMID:27936102 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624 		JBrowse link
G Col4a1 collagen type IV alpha 1 chain decreases expression EXP ciglitazone results in decreased expression of COL4A1 mRNA CTD PMID:22193206 NCBI chr16:78,183,533...78,294,412
Ensembl chr16:78,183,533...78,294,412 		JBrowse link
G Col4a5 collagen type IV alpha 5 chain decreases expression EXP ciglitazone results in decreased expression of COL4A5 mRNA CTD PMID:22193206 NCBI chr  X:105,118,762...105,322,699
Ensembl chr  X:105,118,820...105,322,692 		JBrowse link
G Col5a1 collagen type V alpha 1 chain decreases expression EXP ciglitazone results in decreased expression of COL5A1 mRNA CTD PMID:22193206 NCBI chr 3:11,208,429...11,356,715
Ensembl chr 3:11,208,512...11,354,588 		JBrowse link
G Copa COPI coat complex subunit alpha multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of COPA mRNA CTD PMID:16197558 NCBI chr13:84,546,483...84,586,879
Ensembl chr13:84,545,943...84,586,874 		JBrowse link
G Cp ceruloplasmin decreases expression EXP ciglitazone results in decreased expression of CP mRNA CTD PMID:22193206 NCBI chr 2:102,439,433...102,498,075
Ensembl chr 2:102,439,624...102,498,075 		JBrowse link
G Cpm carboxypeptidase M decreases expression EXP ciglitazone results in decreased expression of CPM mRNA CTD PMID:22193206 NCBI chr 7:53,225,647...53,286,220
Ensembl chr 7:53,225,696...53,286,220 		JBrowse link
G Crebbp CREB binding protein multiple interactions
affects response to substance		 ISO ciglitazone inhibits the reaction [CREBBP protein binds to EGFR promoter]; CREBBP protein inhibits the reaction [ciglitazone results in decreased expression of CDK1 protein]; CREBBP protein inhibits the reaction [ciglitazone results in decreased expression of CDK4 protein]; CREBBP protein inhibits the reaction [ciglitazone results in decreased expression of EGFR protein]; CREBBP protein inhibits the reaction [ciglitazone results in decreased expression of MAPK3 protein]; CREBBP protein inhibits the reaction [ciglitazone results in decreased expression of MYC protein]
CREBBP affects the susceptibility to ciglitazone		 CTD PMID:21080969 NCBI chr10:11,335,551...11,461,888
Ensembl chr10:11,335,953...11,461,888 		JBrowse link
G Cstb cystatin B multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of CSTB mRNA CTD PMID:16197558 NCBI chr20:10,245,462...10,247,505
Ensembl chr20:10,245,462...10,247,526 		JBrowse link
G Ctsc cathepsin C multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of CTSC mRNA CTD PMID:16197558 NCBI chr 1:142,028,386...142,059,841
Ensembl chr 1:142,028,392...142,060,387 		JBrowse link
G Cyb5r3 cytochrome b5 reductase 3 multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of CYB5R3 mRNA CTD PMID:16197558 NCBI chr 7:114,306,686...114,324,247
Ensembl chr 7:114,306,685...114,324,298 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of CYP1A2 mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of CYP1A2 mRNA CTD PMID:16197558 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions
increases expression		 ISO ciglitazone promotes the reaction [Niflumic Acid results in increased expression of DDIT3 protein]; DDIT3 mutant form inhibits the reaction [[Niflumic Acid co-treated with ciglitazone] results in increased activity of BAX protein]; DDIT3 mutant form inhibits the reaction [[Niflumic Acid co-treated with ciglitazone] results in increased cleavage of BID protein]; DDIT3 mutant form inhibits the reaction [[Niflumic Acid co-treated with ciglitazone] results in increased cleavage of CASP3 protein]; DDIT3 mutant form inhibits the reaction [[Niflumic Acid co-treated with ciglitazone] results in increased cleavage of CASP9 protein]; DDIT3 mutant form inhibits the reaction [ciglitazone promotes the reaction [Niflumic Acid results in increased activity of CASP8 protein]]; DDIT3 mutant form inhibits the reaction [ciglitazone promotes the reaction [Niflumic Acid results in increased cleavage of PARP1 protein]]; DDIT3 mutant form inhibits the reaction [Niflumic Acid promotes the reaction [ciglitazone results in increased activity of CASP8 protein]]; DDIT3 mutant form inhibits the reaction [Niflumic Acid promotes the reaction [ciglitazone results in increased cleavage of PARP1 protein]]; DDIT3 results in increased susceptibility to [Niflumic Acid co-treated with ciglitazone]; Niflumic Acid promotes the reaction [ciglitazone results in increased expression of DDIT3 protein] CTD PMID:21067863 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201 		JBrowse link
G Dgat1 diacylglycerol O-acyltransferase 1 increases expression ISO ciglitazone results in increased expression of DGAT1 mRNA CTD PMID:16847310 NCBI chr 7:108,223,860...108,235,413
Ensembl chr 7:108,218,524...108,234,299 		JBrowse link
G Dio2 iodothyronine deiodinase 2 multiple interactions
increases activity		 ISO PPARG protein promotes the reaction [ciglitazone results in increased activity of DIO2 protein] CTD PMID:19036883 NCBI chr 6:109,665,523...109,679,809
Ensembl chr 6:109,665,523...109,679,809 		JBrowse link
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of DKK1 mRNA CTD PMID:16197558 NCBI chr 1:228,381,521...228,385,202
Ensembl chr 1:228,381,521...228,385,202 		JBrowse link
G Dlc1 DLC1 Rho GTPase activating protein multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of DLC1 mRNA CTD PMID:16197558 NCBI chr16:55,246,716...55,671,441
Ensembl chr16:55,291,584...55,671,439 		JBrowse link
G Dnajb5 DnaJ heat shock protein family (Hsp40) member B5 increases expression EXP ciglitazone results in increased expression of DNAJB5 mRNA CTD PMID:22193206 NCBI chr 5:57,176,840...57,185,492
Ensembl chr 5:57,176,845...57,185,490 		JBrowse link
G Dok4 docking protein 4 multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of DOK4 mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of DOK4 mRNA CTD PMID:16197558 NCBI chr19:10,146,520...10,157,187
Ensembl chr19:10,146,474...10,158,203 		JBrowse link
G Dusp1 dual specificity phosphatase 1 increases expression EXP ciglitazone results in increased expression of DUSP1 mRNA CTD PMID:22193206 NCBI chr10:16,680,489...16,683,276 JBrowse link
G Efemp1 EGF containing fibulin extracellular matrix protein 1 decreases expression EXP ciglitazone results in decreased expression of EFEMP1 mRNA CTD PMID:22193206 NCBI chr14:102,610,813...102,690,027
Ensembl chr14:102,610,908...102,690,018 		JBrowse link
G Efna1 ephrin A1 multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of EFNA1 mRNA CTD PMID:16197558 NCBI chr 2:174,681,676...174,690,306
Ensembl chr 2:174,681,682...174,690,866 		JBrowse link
G Egfr epidermal growth factor receptor multiple interactions
decreases expression		 ISO ciglitazone inhibits the reaction [CREBBP protein binds to EGFR promoter]; ciglitazone inhibits the reaction [NCOA1 protein binds to EGFR promoter]; CREBBP protein inhibits the reaction [ciglitazone results in decreased expression of EGFR protein]; NCOA1 protein inhibits the reaction [ciglitazone results in decreased expression of EGFR protein] CTD PMID:21080969 NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Eif2a eukaryotic translation initiation factor 2A increases phosphorylation
multiple interactions		 ISO ciglitazone results in increased phosphorylation of EIF2A protein
ciglitazone promotes the reaction [Niflumic Acid results in increased phosphorylation of EIF2A protein]; Niflumic Acid promotes the reaction [ciglitazone results in increased phosphorylation of EIF2A protein]		 CTD PMID:21067863 NCBI chr 2:142,761,303...142,794,767
Ensembl chr 2:142,761,416...142,795,068 		JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 multiple interactions
increases phosphorylation		 ISO ciglitazone promotes the reaction [Niflumic Acid results in increased phosphorylation of EIF2AK3 protein]; Niflumic Acid promotes the reaction [ciglitazone results in increased phosphorylation of EIF2AK3 protein] CTD PMID:21067863 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911 		JBrowse link
G Elf5 E74 like ETS transcription factor 5 multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of ELF5 mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of ELF5 mRNA CTD PMID:16197558 NCBI chr 3:89,808,836...89,836,977
Ensembl chr 3:89,797,880...89,836,973 		JBrowse link
G Emp1 epithelial membrane protein 1 increases expression EXP ciglitazone results in increased expression of EMP1 mRNA CTD PMID:22193206 NCBI chr 4:168,212,901...168,233,039
Ensembl chr 4:168,212,861...168,232,904 		JBrowse link
G Epas1 endothelial PAS domain protein 1 multiple interactions ISO [ciglitazone binds to PPARG protein] which results in increased expression of EPAS1 mRNA CTD PMID:16197558 NCBI chr 6:7,790,236...7,871,246
Ensembl chr 6:7,790,647...7,871,228 		JBrowse link
G Fabp1 fatty acid binding protein 1 multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of FABP1 mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of FABP1 mRNA CTD PMID:16197558 NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788 		JBrowse link
G Fabp4 fatty acid binding protein 4 increases expression ISO ciglitazone results in increased expression of FABP4 mRNA CTD PMID:16847310 NCBI chr 2:91,580,858...91,585,578
Ensembl chr 2:91,580,885...91,585,578 		JBrowse link
G Fads1 fatty acid desaturase 1 multiple interactions
increases expression		 ISO [beta-hydroxy simvastatin acid co-treated with ciglitazone] results in increased expression of FADS1 mRNA
ciglitazone results in increased expression of FADS1 mRNA		 CTD PMID:17655842 NCBI chr 1:206,827,724...206,842,734
Ensembl chr 1:206,827,765...206,842,734 		JBrowse link
G Fam102a family with sequence similarity 102, member A multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of FAM102A mRNA CTD PMID:16197558 NCBI chr 3:15,823,147...15,854,651
Ensembl chr 3:15,823,144...15,854,643 		JBrowse link
G Fam13a family with sequence similarity 13, member A multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of FAM13A mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of FAM13A mRNA CTD PMID:16197558 NCBI chr 4:88,056,521...88,155,782
Ensembl chr 4:88,058,403...88,155,860 		JBrowse link
G Flnb filamin B multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of FLNB mRNA CTD PMID:16197558 NCBI chr15:16,961,999...17,095,059
Ensembl chr15:16,962,003...17,095,006 		JBrowse link
G Flnc filamin C increases expression EXP ciglitazone results in increased expression of FLNC mRNA CTD PMID:22193206 NCBI chr 4:58,034,088...58,061,882
Ensembl chr 4:58,034,189...58,061,844 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit decreases expression
increases expression		 ISO
EXP		 ciglitazone results in decreased expression of FOS
ciglitazone results in increased expression of FOS mRNA		 CTD PMID:12787395 PMID:22193206 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Foxo1 forkhead box O1 multiple interactions ISO [ciglitazone binds to PPARG protein] which results in increased expression of FOXO1 mRNA CTD PMID:16197558 NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790 		JBrowse link
G Gadd45g growth arrest and DNA-damage-inducible, gamma increases expression EXP ciglitazone results in increased expression of GADD45G mRNA CTD PMID:22193206 NCBI chr17:13,376,842...13,378,587
Ensembl chr17:13,376,839...13,378,610 		JBrowse link
G Galnt2 polypeptide N-acetylgalactosaminyltransferase 2 multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of GALNT2 mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of GALNT2 mRNA CTD PMID:16197558 NCBI chr19:52,213,226...52,324,816
Ensembl chr19:52,213,351...52,324,813 		JBrowse link
G Gast gastrin multiple interactions ISO GAST protein inhibits the reaction [ciglitazone results in increased expression of CASP3 mRNA] CTD PMID:15387324 NCBI chr10:85,264,832...85,269,393
Ensembl chr10:85,264,832...85,267,496 		JBrowse link
G Gcn1 GCN1 activator of EIF2AK4 multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of GCN1 mRNA CTD PMID:16197558 NCBI chr12:40,991,512...41,052,661
Ensembl chr12:40,991,512...41,052,555 		JBrowse link
G Gk glycerol kinase multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of GK mRNA CTD PMID:16197558 NCBI chr  X:50,162,089...50,238,707
Ensembl chr  X:50,163,123...50,238,631 		JBrowse link
G Gpx3 glutathione peroxidase 3 multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of GPX3 mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of GPX3 mRNA CTD PMID:16197558 NCBI chr10:39,028,624...39,036,695
Ensembl chr10:39,028,570...39,037,035 		JBrowse link
G Gramd2b GRAM domain containing 2B multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of GRAMD2B mRNA CTD PMID:16197558 NCBI chr18:49,884,014...49,981,955
Ensembl chr18:49,884,014...49,981,953 		JBrowse link
G Gstm2 glutathione S-transferase mu 2 decreases expression EXP ciglitazone results in decreased expression of GSTM2 mRNA CTD PMID:22193206 NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961 		JBrowse link
G Gys2 glycogen synthase 2 increases expression ISO ciglitazone results in increased expression of GYS2 mRNA; ciglitazone results in increased expression of GYS2 protein CTD PMID:17437057 NCBI chr 4:175,365,054...175,406,228
Ensembl chr 4:175,365,054...175,406,228 		JBrowse link
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of HADHA mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of HADHA mRNA CTD PMID:16197558 NCBI chr 6:26,187,969...26,227,605
Ensembl chr 6:26,187,956...26,227,869 		JBrowse link
G Hamp hepcidin antimicrobial peptide multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of HAMP mRNA CTD PMID:16197558 NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha decreases expression EXP ciglitazone results in decreased expression of HIF1A mRNA CTD PMID:22193206 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261 		JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of HMGCS2 mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of HMGCS2 mRNA CTD PMID:16197558 NCBI chr 2:185,875,609...185,903,505
Ensembl chr 2:185,875,616...185,902,130 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of HMOX1 mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of HMOX1 mRNA CTD PMID:16197558 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hpn hepsin multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of HPN mRNA CTD PMID:16197558 NCBI chr 1:86,337,085...86,352,785
Ensembl chr 1:86,337,087...86,352,811 		JBrowse link
G Icam1 intercellular adhesion molecule 1 decreases expression ISO ciglitazone results in decreased expression of ICAM1 mRNA; ciglitazone results in decreased expression of ICAM1 protein CTD PMID:17425601 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Ier2 immediate early response 2 increases expression EXP ciglitazone results in increased expression of IER2 mRNA CTD PMID:22193206 NCBI chr19:23,494,551...23,496,075
Ensembl chr19:23,494,184...23,499,211 		JBrowse link
G Ifng interferon gamma multiple interactions
decreases secretion		 ISO 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [ciglitazone results in decreased secretion of IFNG protein]; ciglitazone inhibits the reaction [[IFNG protein results in increased expression of NOS2 protein] which results in increased chemical synthesis of Nitric Oxide]; ciglitazone inhibits the reaction [IFNG protein results in increased expression of IRF1 mRNA]; ciglitazone inhibits the reaction [IFNG protein results in increased expression of NOS2 mRNA]; T 0070907 inhibits the reaction [ciglitazone results in decreased secretion of IFNG protein] CTD PMID:12847270 PMID:16844232 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases expression		 ISO ciglitazone inhibits the reaction [Thioglycolates results in increased secretion of IL1B protein]
ciglitazone promotes the reaction [IL1B protein results in increased abundance of Dinoprostone]; Dexamethasone inhibits the reaction [ciglitazone results in increased expression of [IL1B protein results in increased expression of PTGS2 protein]]		 CTD PMID:12517972 PMID:12624547 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il1r1 interleukin 1 receptor type 1 multiple interactions ISO [ciglitazone binds to PPARG protein] which results in increased expression of IL1R1 mRNA CTD PMID:16197558 NCBI chr 9:42,504,917...42,580,958
Ensembl chr 9:42,504,735...42,579,937 		JBrowse link
G Il2 interleukin 2 multiple interactions ISO ciglitazone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcium Ionophores] results in increased secretion of IL2 protein]; T 0070907 inhibits the reaction [ciglitazone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcium Ionophores] results in increased secretion of IL2 protein]] CTD PMID:21511917 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO ciglitazone inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; ciglitazone inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]; Mifepristone inhibits the reaction [ciglitazone inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]] CTD PMID:15684043 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Il6st interleukin 6 cytokine family signal transducer multiple interactions ISO [ciglitazone binds to PPARG protein] which results in increased expression of IL6ST mRNA CTD PMID:16197558 NCBI chr 2:44,065,979...44,106,255
Ensembl chr 2:44,066,130...44,109,936 		JBrowse link
G Irf1 interferon regulatory factor 1 multiple interactions ISO ciglitazone inhibits the reaction [IFNG protein results in increased expression of IRF1 mRNA] CTD PMID:12847270 NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166 		JBrowse link
G Itgb5 integrin subunit beta 5 multiple interactions ISO [ciglitazone binds to PPARG protein] which results in increased expression of ITGB5 mRNA CTD PMID:16197558 NCBI chr11:66,828,428...66,944,231
Ensembl chr11:66,829,285...66,944,472 		JBrowse link
G Itih3 inter-alpha trypsin inhibitor, heavy chain 3 multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of ITIH3 mRNA CTD PMID:16197558 NCBI chr16:6,101,922...6,117,154
Ensembl chr16:6,101,930...6,116,924 		JBrowse link
G Jag1 jagged canonical Notch ligand 1 multiple interactions ISO [ciglitazone binds to PPARG protein] which results in increased expression of JAG1 mRNA CTD PMID:16197558 NCBI chr 3:124,406,794...124,442,220
Ensembl chr 3:124,406,794...124,442,209 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions		 EXP
ISO		 ciglitazone results in increased expression of JUN mRNA
ciglitazone results in increased expression of JUN mRNA; ciglitazone results in increased expression of JUN protein
[Bucladesine co-treated with ciglitazone] results in increased expression of and results in increased phosphorylation of JUN protein; [ciglitazone co-treated with Bucladesine] promotes the reaction [JUN protein results in increased expression of STAR mRNA]; Bucladesine promotes the reaction [ciglitazone results in increased expression of JUN mRNA]; ciglitazone promotes the reaction [Bucladesine results in increased expression of JUN mRNA]		 CTD PMID:19698295 PMID:22193206 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Klf4 Kruppel like factor 4 increases expression EXP ciglitazone results in increased expression of KLF4 mRNA CTD PMID:22193206 NCBI chr 5:70,278,843...70,283,751
Ensembl chr 5:70,278,972...70,283,602 		JBrowse link
G Lama1 laminin subunit alpha 1 decreases expression EXP ciglitazone results in decreased expression of LAMA1 mRNA CTD PMID:22193206 NCBI chr 9:107,692,770...107,816,847
Ensembl chr 9:107,692,770...107,817,478 		JBrowse link
G Lamb2 laminin subunit beta 2 decreases expression EXP ciglitazone results in decreased expression of LAMB2 mRNA CTD PMID:22193206 NCBI chr 8:109,178,367...109,190,552
Ensembl chr 8:109,178,409...109,190,549 		JBrowse link
G Lgals3 galectin 3 multiple interactions ISO [ciglitazone binds to PPARG protein] which results in increased expression of LGALS3 mRNA CTD PMID:16197558 NCBI chr15:20,620,083...20,632,019
Ensembl chr15:20,607,692...20,632,025 		JBrowse link
G Lif LIF, interleukin 6 family cytokine multiple interactions ISO 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [ciglitazone inhibits the reaction [LIF protein results in increased expression of STAT3 protein]]; 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [ciglitazone inhibits the reaction [LIF protein results in increased phosphorylation of STAT3 protein]]; ciglitazone inhibits the reaction [LIF protein results in increased expression of STAT3 protein]; ciglitazone inhibits the reaction [LIF protein results in increased phosphorylation of STAT3 protein]; T 0070907 inhibits the reaction [ciglitazone inhibits the reaction [LIF protein results in increased expression of STAT3 protein]]; T 0070907 inhibits the reaction [ciglitazone inhibits the reaction [LIF protein results in increased phosphorylation of STAT3 protein]] CTD PMID:19922793 NCBI chr14:79,131,049...79,140,486
Ensembl chr14:79,134,574...79,140,482 		JBrowse link
G Lipc lipase C, hepatic type multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of LIPC mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of LIPC mRNA CTD PMID:16197558 NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464 		JBrowse link
G Lmcd1 LIM and cysteine-rich domains 1 multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of LMCD1 mRNA CTD PMID:16197558 NCBI chr 4:145,393,153...145,452,049
Ensembl chr 4:145,393,145...145,452,046 		JBrowse link
G Lox lysyl oxidase multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of LOX mRNA CTD PMID:16197558 NCBI chr18:45,964,311...46,041,477
Ensembl chr18:45,967,343...46,041,477 		JBrowse link
G Lpcat1 lysophosphatidylcholine acyltransferase 1 multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of LPCAT1 mRNA CTD PMID:16197558 NCBI chr 1:29,766,070...29,816,401
Ensembl chr 1:29,766,071...29,816,401 		JBrowse link
G Lpcat3 lysophosphatidylcholine acyltransferase 3 multiple interactions ISO [ciglitazone binds to PPARG protein] which results in increased expression of LPCAT3 mRNA CTD PMID:16197558 NCBI chr 4:157,468,397...157,509,889
Ensembl chr 4:157,468,290...157,509,880 		JBrowse link
G Map4k3 mitogen-activated protein kinase kinase kinase kinase 3 multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of MAP4K3 mRNA CTD PMID:16197558 NCBI chr 6:14,276,623...14,446,321
Ensembl chr 6:14,277,121...14,446,334 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 decreases phosphorylation
increases phosphorylation
multiple interactions		 ISO
EXP		 ciglitazone results in decreased phosphorylation of MAPK1 protein
ciglitazone results in increased phosphorylation of MAPK1 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [ciglitazone results in increased phosphorylation of MAPK1 protein]; Glutathione inhibits the reaction [ciglitazone results in increased phosphorylation of MAPK1 protein]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [ciglitazone results in increased phosphorylation of MAPK1 protein]		 CTD PMID:12083801 PMID:19140230 PMID:20578043 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk14 mitogen activated protein kinase 14 multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of MAPK14 mRNA CTD PMID:16197558 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 decreases phosphorylation
increases phosphorylation
multiple interactions
decreases expression		 ISO
EXP		 ciglitazone results in decreased phosphorylation of MAPK3 protein
ciglitazone results in increased phosphorylation of MAPK3 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [ciglitazone results in increased phosphorylation of MAPK3 protein]; Glutathione inhibits the reaction [ciglitazone results in increased phosphorylation of MAPK3 protein]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [ciglitazone results in increased phosphorylation of MAPK3 protein]
CREBBP protein inhibits the reaction [ciglitazone results in decreased expression of MAPK3 protein]; NCOA1 protein inhibits the reaction [ciglitazone results in decreased expression of MAPK3 protein]		 CTD PMID:12083801 PMID:19140230 PMID:20578043 PMID:21080969 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mki67 marker of proliferation Ki-67 multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of MKI67 mRNA CTD PMID:16197558 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762 		JBrowse link
G Mogat1 monoacylglycerol O-acyltransferase 1 increases expression ISO ciglitazone results in increased expression of MOGAT1 mRNA CTD PMID:16847310 NCBI chr 9:79,980,963...79,988,513
Ensembl chr 9:79,956,649...79,988,513 		JBrowse link
G Mpc1 mitochondrial pyruvate carrier 1 multiple interactions ISO [ciglitazone binds to PPARG protein] which results in increased expression of MPC1 mRNA CTD PMID:16197558 NCBI chr 1:52,437,745...52,449,369
Ensembl chr 1:52,437,741...52,449,400 		JBrowse link
G Mpzl2 myelin protein zero-like 2 multiple interactions ISO [ciglitazone binds to PPARG protein] which results in increased expression of MPZL2 mRNA CTD PMID:16197558 NCBI chr 8:45,348,285...45,359,298
Ensembl chr 8:45,348,285...45,359,298 		JBrowse link
G Mtmr4 myotubularin related protein 4 multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of MTMR4 mRNA CTD PMID:16197558 NCBI chr10:72,393,411...72,416,342
Ensembl chr10:72,392,551...72,416,342 		JBrowse link
G Mxra8 matrix remodeling associated 8 decreases expression EXP ciglitazone results in decreased expression of MXRA8 mRNA CTD PMID:22193206 NCBI chr 5:166,448,919...166,453,645
Ensembl chr 5:166,449,154...166,453,636 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor multiple interactions
decreases expression		 ISO CREBBP protein inhibits the reaction [ciglitazone results in decreased expression of MYC protein]; NCOA1 protein inhibits the reaction [ciglitazone results in decreased expression of MYC protein] CTD PMID:21080969 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Ncoa1 nuclear receptor coactivator 1 multiple interactions
affects response to substance		 ISO ciglitazone inhibits the reaction [NCOA1 protein binds to EGFR promoter]; NCOA1 protein inhibits the reaction [ciglitazone results in decreased expression of CDK1 protein]; NCOA1 protein inhibits the reaction [ciglitazone results in decreased expression of CDK4 protein]; NCOA1 protein inhibits the reaction [ciglitazone results in decreased expression of EGFR protein]; NCOA1 protein inhibits the reaction [ciglitazone results in decreased expression of MAPK3 protein]; NCOA1 protein inhibits the reaction [ciglitazone results in decreased expression of MYC protein]
NCOA1 affects the susceptibility to ciglitazone		 CTD PMID:21080969 NCBI chr 6:27,232,609...27,507,992
Ensembl chr 6:27,232,611...27,475,664 		JBrowse link
G Ndrg2 NDRG family member 2 multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of NDRG2 mRNA CTD PMID:16197558 NCBI chr15:24,600,981...24,609,621
Ensembl chr15:24,600,982...24,609,626 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions
decreases activity		 ISO ciglitazone results in decreased activity of [RELA protein binds to NFKB1 protein]
ciglitazone results in decreased activity of NFKB1 protein		 CTD PMID:17425601 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404 		JBrowse link
G Nfkbia NFKB inhibitor alpha decreases expression ISO ciglitazone results in decreased expression of NFKBIA protein CTD PMID:12517972 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO ciglitazone inhibits the reaction [[IFNG protein results in increased expression of NOS2 protein] which results in increased chemical synthesis of Nitric Oxide]; ciglitazone inhibits the reaction [IFNG protein results in increased expression of NOS2 mRNA]; ciglitazone inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; ciglitazone inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] CTD PMID:12031542 PMID:12847270 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Npc1 NPC intracellular cholesterol transporter 1 multiple interactions ISO [ciglitazone binds to PPARG protein] which results in increased expression of NPC1 mRNA CTD PMID:16197558 NCBI chr18:3,379,482...3,425,100
Ensembl chr18:3,379,482...3,425,049 		JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of NR1H3 mRNA CTD PMID:16197558 NCBI chr 3:77,158,808...77,168,907
Ensembl chr 3:77,158,808...77,168,722 		JBrowse link
G Nr2f1 nuclear receptor subfamily 2, group F, member 1 multiple interactions ISO NR2F1 protein promotes the reaction [[SR 11237 co-treated with ciglitazone] results in increased expression of RARB protein] CTD PMID:12839938 NCBI chr 2:8,040,375...8,050,123
Ensembl chr 2:8,040,377...8,050,123 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 affects localization ISO ciglitazone affects the localization of NR3C1 protein CTD PMID:15684043 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375 		JBrowse link
G Nrep neuronal regeneration related protein multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of NREP mRNA CTD PMID:16197558 NCBI chr18:25,017,069...25,046,564
Ensembl chr18:25,017,083...25,046,591 		JBrowse link
G Oas1a 2'-5' oligoadenylate synthetase 1A multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of OAS1 mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of OAS1 mRNA CTD PMID:16197558 NCBI chr12:35,669,798...35,680,505
Ensembl chr12:35,669,801...35,680,517 		JBrowse link
G Optn optineurin multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of OPTN mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of OPTN mRNA CTD PMID:16197558 NCBI chr17:73,209,572...73,260,251
Ensembl chr17:73,209,575...73,260,251 		JBrowse link
G Osmr oncostatin M receptor multiple interactions ISO [ciglitazone binds to PPARG protein] which results in increased expression of OSMR mRNA CTD PMID:16197558 NCBI chr 2:55,907,119...55,961,373
Ensembl chr 2:55,907,132...55,961,262 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions
increases cleavage		 ISO benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [ciglitazone promotes the reaction [Niflumic Acid results in increased cleavage of PARP1 protein]]; benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [Niflumic Acid promotes the reaction [ciglitazone results in increased cleavage of PARP1 protein]]; ciglitazone promotes the reaction [Niflumic Acid results in increased cleavage of PARP1 protein]; ciglitazone results in increased cleavage of and results in increased activity of PARP1 protein; DDIT3 mutant form inhibits the reaction [ciglitazone promotes the reaction [Niflumic Acid results in increased cleavage of PARP1 protein]]; DDIT3 mutant form inhibits the reaction [Niflumic Acid promotes the reaction [ciglitazone results in increased cleavage of PARP1 protein]]; Niflumic Acid promotes the reaction [ciglitazone results in increased cleavage of PARP1 protein] CTD PMID:15492468 PMID:21067863 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of PCK1 mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of PCK1 mRNA CTD PMID:16197558 NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191 		JBrowse link
G Pdzk1 PDZ domain containing 1 multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of PDZK1 mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of PDZK1 mRNA CTD PMID:16197558 NCBI chr 2:184,376,161...184,407,514
Ensembl chr 2:184,376,161...184,407,514 		JBrowse link
G Phka2 phosphorylase kinase regulatory subunit alpha 2 multiple interactions ISO [ciglitazone binds to PPARG protein] which results in increased expression of PHKA2 mRNA CTD PMID:16197558 NCBI chr  X:34,170,959...34,293,498
Ensembl chr  X:34,171,323...34,293,466 		JBrowse link
G Phlpp1 PH domain and leucine rich repeat protein phosphatase 1 multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of PHLPP1 mRNA CTD PMID:16197558 NCBI chr13:22,308,532...22,530,978
Ensembl chr13:22,308,548...22,530,977 		JBrowse link
G Pim1 Pim-1 proto-oncogene, serine/threonine kinase multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of PIM1 mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of PIM1 mRNA CTD PMID:16197558 NCBI chr20:7,554,921...7,559,174
Ensembl chr20:7,554,921...7,559,174 		JBrowse link
G Pla2g2a phospholipase A2 group IIA multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of PLA2G2A mRNA CTD PMID:16197558 NCBI chr 5:151,076,442...151,079,019
Ensembl chr 5:151,076,442...151,079,014 		JBrowse link
G Plac8 placenta associated 8 multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of PLAC8 mRNA CTD PMID:16197558 NCBI chr14:9,052,601...9,074,264
Ensembl chr14:9,063,048...9,074,264 		JBrowse link
G Plcxd1 phosphatidylinositol-specific phospholipase C, X domain containing 1 multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of PLCXD1 mRNA CTD PMID:16197558 NCBI chr12:46,578,917...46,582,181
Ensembl chr12:46,579,225...46,582,392 		JBrowse link
G Plin2 perilipin 2 multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of PLIN2 mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of PLIN2 mRNA CTD PMID:16197558 NCBI chr 5:101,156,643...101,211,738
Ensembl chr 5:101,154,411...101,242,319 		JBrowse link
G Plod2 procollagen lysine, 2-oxoglutarate 5-dioxygenase 2 decreases expression EXP ciglitazone results in decreased expression of PLOD2 mRNA CTD PMID:22193206 NCBI chr 8:93,084,548...93,167,255
Ensembl chr 8:93,084,513...93,167,255 		JBrowse link
G Plscr4 phospholipid scramblase 4 multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of PLSCR4 mRNA CTD PMID:16197558 NCBI chr 8:92,987,290...93,026,056
Ensembl chr 8:92,987,381...93,026,049 		JBrowse link
G Pmm1 phosphomannomutase 1 multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of PMM1 mRNA CTD PMID:16197558 NCBI chr 7:113,466,632...113,477,004
Ensembl chr 7:113,466,632...113,477,022 		JBrowse link
G Pnrc1 proline-rich nuclear receptor coactivator 1 multiple interactions ISO [ciglitazone binds to PPARG protein] which results in increased expression of PNRC1 mRNA CTD PMID:16197558 NCBI chr 5:47,647,070...47,657,832
Ensembl chr 5:47,647,071...47,650,161 		JBrowse link
G Por cytochrome p450 oxidoreductase multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of POR mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of POR mRNA CTD PMID:16197558 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions
decreases expression
increases expression		 ISO ciglitazone promotes the reaction [PPARA protein results in increased expression of PTGS2 mRNA]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [ciglitazone results in increased expression of PPARA mRNA]; nimesulide inhibits the reaction [ciglitazone promotes the reaction [PPARA protein results in increased expression of PTGS2 mRNA]]; nimesulide inhibits the reaction [ciglitazone results in increased expression of PPARA mRNA]
ciglitazone results in decreased expression of PPARA mRNA		 CTD PMID:11056218 PMID:11840453 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions
affects localization
increases expression
decreases response to substance
affects binding
increases localization
increases activity		 ISO
EXP		 [ciglitazone binds to PPARG protein alternative form] which results in increased expression of ABHD3 mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of ACAA2 mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of ACADM mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of ACADVL mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of ACSM3 mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of AKR1C1 mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of AKR1C2 mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of ANG mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of ANGPTL4 mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of APOL1 mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of APOM mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of AQP3 mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of ARHGEF2 mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of ATF7IP2 mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of BCL6 mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of BDH1 mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of BHMT mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of BLVRB mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of CAT mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of CCL14 mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of CCL15 mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of CCL20 mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of CDH1 mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of CIDEC mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of COBLL1 mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of COPA mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of CSTB mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of CTSC mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of CYB5R3 mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of CYP1A2 mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of DKK1 mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of DLC1 mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of DOK4 mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of EFNA1 mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of ELF5 mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of FABP1 mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of FAM102A mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of FAM13A mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of FLNB mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of GALNT2 mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of GCN1 mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of GK mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of GK3P mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of GPX3 mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of GRAMD2B mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of HADHA mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of HAMP mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of HMGCS2 mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of HMOX1 mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of HPN mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of ITIH3 mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of LIPC mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of LMCD1 mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of LOX mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of LPCAT1 mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of MAGED4 mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of MAGED4B mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of MAP4K3 mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of MAPK14 mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of MKI67 mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of MTMR4 mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of NDRG2 mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of NR1H3 mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of NREP mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of OAS1 mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of OPTN mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of PALM2AKAP2 mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of PCK1 mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of PDZK1 mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of PHLPP1 mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of PIM1 mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of PLA2G2A mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of PLAC8 mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of PLCXD1 mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of PLIN2 mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of PLSCR4 mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of PMM1 mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of POR mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of PRKCD mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of PSD4 mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of RETSAT mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of RNASE4 mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of RNF128 mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of RPS6KC1 mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of S100P mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of SEC23A mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of SEMA3G mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of SEPTIN10 mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of SERPINE1 mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of SLC30A10 mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of SLC50A1 mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of SNRK mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of SORL1 mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of SOWAHC mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of STBD1 mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of SUN2 mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of TCAF1 mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of TIMP3 mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of TMEM53 mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of TNS1 mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of TRAF3IP2 mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of UGT1A6 mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of UGT1A9 mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of VEGFA mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of VNN1 mRNA; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of ZNF185 mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of ABHD3 mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of ACAA1 mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of ACADM mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of ACSL1 mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of AKR1C1 mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of AKR1C2 mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of ANGPTL4 mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of AQP3 mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of CCL14 mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of CCL15 mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of CCL20 mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of CDH1 mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of CEBPD mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of CHMP5 mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of CITED2 mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of CYP1A2 mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of DOK4 mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of ELF5 mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of EPAS1 mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of FABP1 mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of FAM13A mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of FOXO1 mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of GALNT2 mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of GPX3 mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of HADHA mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of HCAR3 mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of HMGCS2 mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of HMOX1 mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of IL1R1 mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of IL6ST mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of ITGB5 mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of JAG1 mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of LGALS3 mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of LIPC mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of LPCAT3 mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of MPC1 mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of MPZL2 mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of NPC1 mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of OAS1 mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of OPTN mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of OSMR mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of PCK1 mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of PDZK1 mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of PHKA2 mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of PIM1 mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of PLIN2 mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of PNRC1 mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of POR mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of RBMS1 mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of RNF10 mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of S100P mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of SERPINE1 mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of SLC30A10 mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of SLC4A7 mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of SORL1 mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of SOWAHC mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of SQSTM1 mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of STBD1 mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of STX7 mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of TBC1D4 mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of TCAF1 mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of TGIF1 mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of TMBIM1 mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of VEGFA mRNA; ciglitazone binds to and results in decreased activity of PPARG protein; ciglitazone binds to and results in increased activity of PPARG protein; ciglitazone inhibits the reaction [Lipopolysaccharides results in decreased expression of PPARG mRNA]; ciglitazone promotes the reaction [PPARG protein results in increased expression of PTGS2 mRNA]; monobutyl phthalate inhibits the reaction [ciglitazone binds to and results in increased activity of PPARG protein]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [ciglitazone results in increased expression of PPARG mRNA]; nimesulide inhibits the reaction [ciglitazone promotes the reaction [PPARG protein results in increased expression of PTGS2 mRNA]]; nimesulide inhibits the reaction [ciglitazone results in increased expression of PPARG mRNA]; norathyriol inhibits the reaction [ciglitazone results in increased activity of PPARG protein]; PPARG promotes the reaction [ciglitazone results in increased expression of PTGS2 mRNA]; PPARG promotes the reaction [ciglitazone results in increased expression of PTGS2 protein]; PPARG protein promotes the reaction [ciglitazone promotes the reaction [SR 11237 results in increased expression of RARB protein]]; PPARG protein promotes the reaction [ciglitazone results in increased activity of DIO2 protein]; Quercetin inhibits the reaction [ciglitazone results in increased activity of PPARG protein]
ciglitazone affects the localization of PPARG protein
ciglitazone results in increased expression of PPARG protein
PPARG protein mutant form results in decreased susceptibility to ciglitazone
ciglitazone results in increased localization of PPARG protein
[ciglitazone co-treated with Bucladesine] affects the expression of PPARG mRNA; [ciglitazone co-treated with Bucladesine] results in increased expression of PPARG protein; ciglitazone binds to and results in increased activity of PPARG protein; ciglitazone inhibits the reaction [PPARG protein affects the reaction [Lipopolysaccharides results in increased abundance of Nitric Oxide]]; ciglitazone inhibits the reaction [PPARG protein results in increased susceptibility to Methamphetamine]; PPARG protein promotes the reaction [ciglitazone results in increased expression of PPARGC1A mRNA]
[ciglitazone binds to and results in increased activity of PPARG protein] which results in increased transport of Glucose; ciglitazone binds to and results in increased activity of PPARG protein; ciglitazone inhibits the reaction [Glycerol results in decreased expression of PPARG protein]
ciglitazone results in increased expression of PPARG mRNA; ciglitazone results in increased expression of PPARG protein		 CTD PMID:11030710 PMID:11343236 PMID:11683414 PMID:11840453 PMID:12391285 More... NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Ppargc1a PPARG coactivator 1 alpha increases expression
multiple interactions		 ISO ciglitazone results in increased expression of PPARGC1A mRNA
PPARG protein promotes the reaction [ciglitazone results in increased expression of PPARGC1A mRNA]		 CTD PMID:16513826 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656 		JBrowse link
G Prkcd protein kinase C, delta multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of PRKCD mRNA CTD PMID:16197558 NCBI chr16:5,769,226...5,807,214
Ensembl chr16:5,769,215...5,799,352 		JBrowse link
G Prodh1 proline dehydrogenase 1 increases expression ISO ciglitazone results in increased expression of PRODH mRNA CTD PMID:17535976 NCBI chr11:82,910,043...82,927,305
Ensembl chr11:82,910,137...82,927,305 		JBrowse link
G Psd4 pleckstrin and Sec7 domain containing 4 multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of PSD4 mRNA CTD PMID:16197558 NCBI chr 3:7,137,069...7,173,571
Ensembl chr 3:7,137,155...7,173,571 		JBrowse link
G Pten phosphatase and tensin homolog increases expression EXP ciglitazone results in increased expression of PTEN protein CTD PMID:20578043 NCBI chr 1:230,631,303...230,696,754
Ensembl chr 1:230,630,338...230,696,838 		JBrowse link
G Ptger3 prostaglandin E receptor 3 multiple interactions ISO [Cisplatin co-treated with ciglitazone] results in decreased expression of PTGER3 CTD PMID:21681689 NCBI chr 2:246,606,131...246,750,970
Ensembl chr 2:246,606,183...246,684,434 		JBrowse link
G Ptges prostaglandin E synthase multiple interactions ISO [Cisplatin co-treated with ciglitazone] results in decreased expression of PTGES CTD PMID:21681689 NCBI chr 3:14,177,892...14,189,236 JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases expression
affects expression		 ISO
EXP		 2-chloro-5-nitrobenzanilide inhibits the reaction [ciglitazone results in increased expression of PTGS2 mRNA]; 2-chloro-5-nitrobenzanilide inhibits the reaction [ciglitazone results in increased expression of PTGS2 protein]; [Cisplatin co-treated with ciglitazone] results in decreased expression of PTGS2; ciglitazone promotes the reaction [PPARA protein results in increased expression of PTGS2 mRNA]; ciglitazone promotes the reaction [PPARG protein results in increased expression of PTGS2 mRNA]; ciglitazone results in increased expression of and results in increased activity of PTGS2 protein; Dexamethasone inhibits the reaction [ciglitazone results in increased expression of [IL1B protein results in increased expression of PTGS2 protein]]; Dexamethasone inhibits the reaction [ciglitazone results in increased expression of and results in increased activity of PTGS2 protein]; nimesulide inhibits the reaction [ciglitazone promotes the reaction [PPARA protein results in increased expression of PTGS2 mRNA]]; nimesulide inhibits the reaction [ciglitazone promotes the reaction [PPARG protein results in increased expression of PTGS2 mRNA]]; nimesulide inhibits the reaction [ciglitazone results in increased expression of PTGS2 mRNA]; nimesulide inhibits the reaction [ciglitazone results in increased expression of PTGS2 protein]; PPARG promotes the reaction [ciglitazone results in increased expression of PTGS2 mRNA]; PPARG promotes the reaction [ciglitazone results in increased expression of PTGS2 protein]
ciglitazone results in increased expression of [IL1B protein results in increased expression of PTGS2 protein]; ciglitazone results in increased expression of PTGS2 mRNA; ciglitazone results in increased expression of PTGS2 protein
ciglitazone promotes the reaction [[PAR-1-activating peptide results in increased expression of PTGS2 protein] which results in increased abundance of Dinoprostone]; ciglitazone promotes the reaction [PAR-1-activating peptide results in increased expression of PTGS2 protein]
ciglitazone inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; ciglitazone inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]
ciglitazone affects the expression of PTGS2 protein		 CTD PMID:11840453 PMID:12031542 PMID:12517972 PMID:16417216 PMID:19954759 More... NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Pxdn peroxidasin decreases expression EXP ciglitazone results in decreased expression of PXDN mRNA CTD PMID:22193206 NCBI chr 6:46,580,749...46,658,345
Ensembl chr 6:46,580,761...46,658,345 		JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase increases activity ISO ciglitazone results in increased activity of RAF1 protein CTD PMID:12083801 NCBI chr 4:148,679,534...148,740,265
Ensembl chr 4:148,679,530...148,740,317 		JBrowse link
G Rarb retinoic acid receptor, beta multiple interactions ISO 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [ciglitazone promotes the reaction [SR 11237 results in increased expression of RARB protein]]; 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [ciglitazone promotes the reaction [SR 11237 results in increased expression of RARB protein]]; ciglitazone promotes the reaction [SR 11237 results in increased expression of RARB protein]; NR2F1 protein promotes the reaction [[SR 11237 co-treated with ciglitazone] results in increased expression of RARB protein]; PPARG protein promotes the reaction [ciglitazone promotes the reaction [SR 11237 results in increased expression of RARB protein]] CTD PMID:12839938 NCBI chr15:8,700,533...9,051,288
Ensembl chr15:8,406,492...9,051,288 		JBrowse link
G Rbms1 RNA binding motif, single stranded interacting protein 1 multiple interactions ISO [ciglitazone binds to PPARG protein] which results in increased expression of RBMS1 mRNA CTD PMID:16197558 NCBI chr 3:45,195,828...45,420,406
Ensembl chr 3:45,197,972...45,420,376 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit decreases activity
multiple interactions		 ISO ciglitazone results in decreased activity of RELA protein
ciglitazone results in decreased activity of [RELA protein binds to NFKB1 protein]		 CTD PMID:17425601 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Retsat retinol saturase multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of RETSAT mRNA CTD PMID:16197558 NCBI chr 4:104,653,306...104,662,069
Ensembl chr 4:104,653,155...104,668,310 		JBrowse link
G Rnase4 ribonuclease A family member 4 multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of RNASE4 mRNA CTD PMID:16197558 NCBI chr15:24,312,765...24,330,116
Ensembl chr15:24,312,464...24,330,117 		JBrowse link
G Rnf10 ring finger protein 10 multiple interactions ISO [ciglitazone binds to PPARG protein] which results in increased expression of RNF10 mRNA CTD PMID:16197558 NCBI chr12:41,341,717...41,375,505
Ensembl chr12:41,341,717...41,375,504 		JBrowse link
G Rnf128 ring finger protein 128 multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of RNF128 mRNA CTD PMID:16197558 NCBI chr  X:103,183,643...103,298,431
Ensembl chr  X:103,183,831...103,298,423 		JBrowse link
G Rps6kc1 ribosomal protein S6 kinase C1 multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of RPS6KC1 mRNA CTD PMID:16197558 NCBI chr13:102,346,160...102,491,000
Ensembl chr13:102,346,160...102,490,303 		JBrowse link
G Sec23a Sec23 homolog A, COPII coat complex component multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of SEC23A mRNA CTD PMID:16197558 NCBI chr 6:76,658,793...76,706,125
Ensembl chr 6:76,658,427...76,706,035 		JBrowse link
G Sema3g semaphorin 3G multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of SEMA3G mRNA CTD PMID:16197558 NCBI chr16:6,413,589...6,425,221
Ensembl chr16:6,413,589...6,425,221 		JBrowse link
G Septin10 septin 10 multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of SEPTIN10 mRNA CTD PMID:16197558 NCBI chr20:27,101,764...27,194,997
Ensembl chr20:27,101,752...27,194,780 		JBrowse link
G Serpine1 serpin family E member 1 multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of SERPINE1 mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of SERPINE1 mRNA CTD PMID:16197558 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657 		JBrowse link
G Slc24a2 solute carrier family 24 member 2 decreases expression EXP ciglitazone results in decreased expression of SLC24A2 mRNA CTD PMID:22193206 NCBI chr 5:101,499,536...101,739,337
Ensembl chr 5:101,502,278...101,739,337 		JBrowse link
G Slc24a4 solute carrier family 24 member 4 decreases expression EXP ciglitazone results in decreased expression of SLC24A4 mRNA CTD PMID:22193206 NCBI chr 6:121,278,746...121,419,811
Ensembl chr 6:121,280,031...121,414,949 		JBrowse link
G Slc30a10 solute carrier family 30, member 10 multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of SLC30A10 mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of SLC30A10 mRNA CTD PMID:16197558 NCBI chr13:96,998,143...97,048,076
Ensembl chr13:96,998,143...97,009,103 		JBrowse link
G Slc4a7 solute carrier family 4 member 7 multiple interactions ISO [ciglitazone binds to PPARG protein] which results in increased expression of SLC4A7 mRNA CTD PMID:16197558 NCBI chr15:10,585,307...10,664,781
Ensembl chr15:10,588,979...10,664,781 		JBrowse link
G Slc50a1 solute carrier family 50 member 1 multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of SLC50A1 mRNA CTD PMID:16197558 NCBI chr 2:174,677,985...174,680,366
Ensembl chr 2:174,677,708...174,680,366 		JBrowse link
G Snrk SNF related kinase multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of SNRK mRNA CTD PMID:16197558 NCBI chr 8:121,779,704...121,833,949
Ensembl chr 8:121,793,302...121,832,323 		JBrowse link
G Sod3 superoxide dismutase 3 decreases expression EXP ciglitazone results in decreased expression of SOD3 mRNA CTD PMID:22193206 NCBI chr14:58,610,104...58,615,845
Ensembl chr14:58,609,958...58,615,990 		JBrowse link
G Sorl1 sortilin related receptor 1 multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of SORL1 mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of SORL1 mRNA CTD PMID:16197558 NCBI chr 8:42,341,704...42,504,435
Ensembl chr 8:42,341,704...42,504,513 		JBrowse link
G Sowahc sosondowah ankyrin repeat domain family member C multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of SOWAHC mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of SOWAHC mRNA CTD PMID:16197558 NCBI chr20:27,195,198...27,199,664 JBrowse link
G Sqstm1 sequestosome 1 multiple interactions ISO [ciglitazone binds to PPARG protein] which results in increased expression of SQSTM1 mRNA CTD PMID:16197558 NCBI chr10:34,525,517...34,536,685
Ensembl chr10:34,525,519...34,536,673 		JBrowse link
G Srxn1 sulfiredoxin 1 increases expression EXP ciglitazone results in increased expression of SRXN1 mRNA CTD PMID:22193206 NCBI chr 3:140,604,490...140,610,050
Ensembl chr 3:140,599,608...140,628,448 		JBrowse link
G Star steroidogenic acute regulatory protein multiple interactions
increases expression		 ISO [Bucladesine co-treated with ciglitazone] results in increased expression of STAR mRNA; [Bucladesine co-treated with ciglitazone] results in increased phosphorylation of STAR protein; [ciglitazone co-treated with Bucladesine] promotes the reaction [JUN protein results in increased expression of STAR mRNA]; Bucladesine promotes the reaction [ciglitazone results in increased expression of STAR mRNA]; Bucladesine promotes the reaction [ciglitazone results in increased expression of STAR protein]; ciglitazone promotes the reaction [Bucladesine results in increased expression of STAR mRNA]; ciglitazone promotes the reaction [Bucladesine results in increased expression of STAR protein] CTD PMID:19698295 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [ciglitazone inhibits the reaction [LIF protein results in increased expression of STAT3 protein]]; 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [ciglitazone inhibits the reaction [LIF protein results in increased phosphorylation of STAT3 protein]]; ciglitazone inhibits the reaction [LIF protein results in increased expression of STAT3 protein]; ciglitazone inhibits the reaction [LIF protein results in increased phosphorylation of STAT3 protein]; T 0070907 inhibits the reaction [ciglitazone inhibits the reaction [LIF protein results in increased expression of STAT3 protein]]; T 0070907 inhibits the reaction [ciglitazone inhibits the reaction [LIF protein results in increased phosphorylation of STAT3 protein]] CTD PMID:19922793 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
G Stbd1 starch binding domain 1 multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of STBD1 mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of STBD1 mRNA CTD PMID:16197558 NCBI chr14:15,470,452...15,473,857
Ensembl chr14:15,469,582...15,477,443 		JBrowse link
G Stx7 syntaxin 7 multiple interactions ISO [ciglitazone binds to PPARG protein] which results in increased expression of STX7 mRNA CTD PMID:16197558 NCBI chr 1:21,197,075...21,237,320
Ensembl chr 1:21,197,075...21,237,279 		JBrowse link
G Sun2 Sad1 and UNC84 domain containing 2 multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of SUN2 mRNA CTD PMID:16197558 NCBI chr 7:111,275,374...111,292,565
Ensembl chr 7:111,275,380...111,292,553 		JBrowse link
G Tbc1d4 TBC1 domain family, member 4 multiple interactions
increases phosphorylation		 ISO
EXP		 [ciglitazone binds to PPARG protein] which results in increased expression of TBC1D4 mRNA
ciglitazone results in increased phosphorylation of TBC1D4 protein		 CTD PMID:16197558 PMID:18063688 NCBI chr15:78,256,030...78,434,168
Ensembl chr15:78,257,121...78,434,265 		JBrowse link
G Tcaf1 TRPM8 channel-associated factor 1 multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of TCAF1 mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of TCAF1 mRNA CTD PMID:16197558 NCBI chr 4:71,589,674...71,639,309
Ensembl chr 4:71,591,200...71,613,309 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO ciglitazone inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 mRNA]; ciglitazone inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA] CTD PMID:18162602 PMID:27936102 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Tgif1 TGFB-induced factor homeobox 1 multiple interactions ISO [ciglitazone binds to PPARG protein] which results in increased expression of TGIF1 mRNA CTD PMID:16197558 NCBI chr 9:110,748,094...110,757,714
Ensembl chr 9:110,720,921...110,757,802 		JBrowse link
G Thra thyroid hormone receptor alpha decreases activity EXP ciglitazone results in decreased activity of THRA protein CTD PMID:16023420 NCBI chr10:83,701,885...83,729,408
Ensembl chr10:83,700,755...83,729,936 		JBrowse link
G Timp3 TIMP metallopeptidase inhibitor 3 multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of TIMP3 mRNA CTD PMID:16197558 NCBI chr 7:17,520,827...17,571,871
Ensembl chr 7:17,521,919...17,571,839 		JBrowse link
G Tmbim1 transmembrane BAX inhibitor motif containing 1 multiple interactions ISO [ciglitazone binds to PPARG protein] which results in increased expression of TMBIM1 mRNA CTD PMID:16197558 NCBI chr 9:75,871,835...75,889,366
Ensembl chr 9:75,871,835...75,889,069 		JBrowse link
G Tmem53 transmembrane protein 53 multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of TMEM53 mRNA CTD PMID:16197558 NCBI chr 5:130,721,780...130,737,692
Ensembl chr 5:130,721,659...130,737,692 		JBrowse link
G Tnfrsf12a TNF receptor superfamily member 12A increases expression EXP ciglitazone results in increased expression of TNFRSF12A mRNA CTD PMID:22193206 NCBI chr10:12,707,077...12,709,071
Ensembl chr10:12,689,890...12,709,045 		JBrowse link
G Tns1 tensin 1 multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of TNS1 mRNA CTD PMID:16197558 NCBI chr 9:75,491,886...75,702,853
Ensembl chr 9:75,495,814...75,703,225 		JBrowse link
G Tpm3 tropomyosin 3 increases expression EXP ciglitazone results in increased expression of TPM3 mRNA CTD PMID:22193206 NCBI chr 2:175,517,198...175,545,014
Ensembl chr 2:175,517,226...175,545,013 		JBrowse link
G Traf3ip2 Traf3 interacting protein 2 multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of TRAF3IP2 mRNA CTD PMID:16197558 NCBI chr20:43,011,405...43,054,654
Ensembl chr20:43,011,450...43,054,667 		JBrowse link
G Trib3 tribbles pseudokinase 3 increases expression EXP ciglitazone results in increased expression of TRIB3 mRNA CTD PMID:22193206 NCBI chr 3:140,809,634...140,815,230
Ensembl chr 3:140,809,043...140,814,497 		JBrowse link
G Ucp2 uncoupling protein 2 decreases expression ISO ciglitazone results in decreased expression of UCP2 mRNA CTD PMID:11056218 NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611 		JBrowse link
G Ucp3 uncoupling protein 3 decreases expression ISO ciglitazone results in decreased expression of UCP3 mRNA CTD PMID:11056218 NCBI chr 1:154,815,777...154,828,764
Ensembl chr 1:154,815,777...154,828,762 		JBrowse link
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of UGT1A6 mRNA CTD PMID:16197558 NCBI chr 9:88,747,229...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of UGT1A9 mRNA CTD PMID:16197558 NCBI chr 9:88,696,981...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions
increases expression		 ISO [[Cisplatin co-treated with ciglitazone] results in decreased expression of VEGFA] which results in decreased abundance of Dinoprostone; [ciglitazone binds to PPARG protein alternative form] which results in increased expression of VEGFA mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of VEGFA mRNA; [Cisplatin co-treated with ciglitazone] results in decreased expression of VEGFA
ciglitazone results in increased expression of VEGFA mRNA		 CTD PMID:16197558 PMID:18599600 PMID:21681689 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
G Vnn1 vanin 1 multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of VNN1 mRNA CTD PMID:16197558 NCBI chr 1:21,537,084...21,547,395
Ensembl chr 1:21,537,094...21,547,395 		JBrowse link
G Xiap X-linked inhibitor of apoptosis decreases expression ISO ciglitazone results in decreased expression of XIAP CTD PMID:17940898 NCBI chr  X:120,890,537...120,938,413
Ensembl chr  X:120,897,907...120,934,700 		JBrowse link
G Zfp185 zinc finger protein 185 multiple interactions ISO [ciglitazone binds to PPARG protein alternative form] which results in increased expression of ZNF185 mRNA CTD PMID:16197558 NCBI chr  X:150,831,869...150,877,652
Ensembl chr  X:150,831,862...150,874,810 		JBrowse link
pioglitazone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abat 4-aminobutyrate aminotransferase multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ABAT mRNA CTD PMID:27935865 NCBI chr10:6,996,688...7,092,835
Ensembl chr10:6,999,819...7,092,835 		JBrowse link
G Abca1 ATP binding cassette subfamily A member 1 affects expression
increases expression		 ISO pioglitazone affects the expression of ABCA1 protein
pioglitazone results in increased expression of ABCA1 mRNA; pioglitazone results in increased expression of ABCA1 protein		 CTD PMID:15381068 PMID:17961437 PMID:19201410 NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170 		JBrowse link
G Abca4 ATP binding cassette subfamily A member 4 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ABCA4 mRNA CTD PMID:27935865 NCBI chr 2:210,164,813...210,302,069
Ensembl chr 2:210,164,813...210,302,069 		JBrowse link
G Abca6 ATP binding cassette subfamily A member 6 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ABCA6 mRNA CTD PMID:27935865 NCBI chr10:95,142,805...95,212,087
Ensembl chr10:95,142,966...95,211,530 		JBrowse link
G Abca8 ATP binding cassette subfamily A member 8 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ABCA8B mRNA CTD PMID:27935865 NCBI chr10:94,917,520...94,991,199
Ensembl chr10:94,917,520...94,990,988 		JBrowse link
G Abcb11 ATP binding cassette subfamily B member 11 decreases activity ISO pioglitazone results in decreased activity of ABCB11 protein CTD PMID:20829430 PMID:22646477 PMID:23956101 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730 		JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A increases expression ISO Pioglitazone results in increased expression of ABCB1 mRNA CTD PMID:31233785 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Abcc9 ATP binding cassette subfamily C member 9 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ABCC9 mRNA CTD PMID:27935865 NCBI chr 4:175,531,854...175,655,849
Ensembl chr 4:175,532,547...175,655,356 		JBrowse link
G Abi3bp ABI family member 3 binding protein multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ABI3BP mRNA CTD PMID:27935865 NCBI chr11:43,912,187...44,128,888
Ensembl chr11:43,913,043...44,128,929 		JBrowse link
G Ablim2 actin binding LIM protein family, member 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ABLIM2 mRNA CTD PMID:27935865 NCBI chr14:74,865,409...74,990,334
Ensembl chr14:74,866,281...74,990,334 		JBrowse link
G Abra actin-binding Rho activating protein multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ABRA mRNA CTD PMID:27935865 NCBI chr 7:72,970,187...72,974,255
Ensembl chr 7:72,970,186...72,974,255 		JBrowse link
G Acat1 acetyl-CoA acetyltransferase 1 decreases expression ISO pioglitazone results in decreased expression of ACAT1 mRNA CTD PMID:15381068 NCBI chr 8:53,979,813...54,008,861
Ensembl chr 8:53,979,813...54,008,855 		JBrowse link
G Acat2 acetyl-CoA acetyltransferase 2 decreases expression ISO Pioglitazone results in decreased expression of ACAT2 mRNA CTD PMID:30031879 NCBI chr 1:47,695,833...47,713,879
Ensembl chr 1:47,695,788...47,752,821 		JBrowse link
G Ace angiotensin I converting enzyme multiple interactions EXP pioglitazone inhibits the reaction [Streptozocin results in increased expression of ACE mRNA]; pioglitazone inhibits the reaction [Streptozocin results in increased expression of ACE protein] CTD PMID:16979161 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131 		JBrowse link
G Ace2 angiotensin I converting enzyme 2 increases expression
increases secretion		 EXP Pioglitazone results in increased expression of ACE2 protein
Pioglitazone results in increased secretion of ACE2 protein		 CTD PMID:24114819 PMID:24558317 NCBI chr  X:30,293,597...30,340,961
Ensembl chr  X:30,293,589...30,340,977 		JBrowse link
G Acod1 aconitate decarboxylase 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of ACOD1 mRNA CTD PMID:27935865 NCBI chr15:79,871,819...79,881,101
Ensembl chr15:79,871,827...79,880,529 		JBrowse link
G Acta1 actin, alpha 1, skeletal muscle multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ACTA1 mRNA CTD PMID:27935865 NCBI chr19:51,883,713...51,886,725
Ensembl chr19:51,883,715...51,886,742 		JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions EXP
ISO		 pioglitazone affects the reaction [Carbon Tetrachloride results in increased expression of ACTA2 protein]
Pioglitazone inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 mRNA]
pioglitazone inhibits the reaction [[Choline deficiency co-treated with Methionine deficiency] results in increased expression of ACTA2 mRNA]; pioglitazone inhibits the reaction [Carbon Tetrachloride results in increased expression of ACTA2 protein]		 CTD PMID:15052691 PMID:16484506 PMID:18513333 PMID:32613381 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554 		JBrowse link
G Actc1 actin, alpha, cardiac muscle 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ACTC1 mRNA CTD PMID:27935865 NCBI chr 3:100,811,987...100,817,523
Ensembl chr 3:100,811,987...100,817,523 		JBrowse link
G Actg2 actin gamma 2, smooth muscle multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ACTG2 mRNA CTD PMID:27935865 NCBI chr 4:116,021,832...116,046,475
Ensembl chr 4:116,021,832...116,046,465 		JBrowse link
G Actn2 actinin alpha 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ACTN2 mRNA CTD PMID:27935865 NCBI chr17:58,143,334...58,210,622
Ensembl chr17:58,142,625...58,210,622 		JBrowse link
G Adam23 ADAM metallopeptidase domain 23 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ADAM23 mRNA CTD PMID:27935865 NCBI chr 9:64,862,878...65,006,515
Ensembl chr 9:64,862,878...65,006,515 		JBrowse link
G Adam5 ADAM metallopeptidase domain 5 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ADAM5 mRNA CTD PMID:27935865 NCBI chr16:67,223,095...67,298,733
Ensembl chr16:67,223,143...67,298,737 		JBrowse link
G Adam9 ADAM metallopeptidase domain 9 multiple interactions ISO pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of ADAM9 mRNA] CTD PMID:20847119 NCBI chr16:67,022,538...67,101,647
Ensembl chr16:67,022,655...67,100,917 		JBrowse link
G Adcy5 adenylate cyclase 5 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ADCY5 mRNA CTD PMID:27935865 NCBI chr11:65,471,612...65,618,877
Ensembl chr11:65,471,612...65,618,974 		JBrowse link
G Adcyap1r1 ADCYAP receptor type I multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ADCYAP1R1 mRNA CTD PMID:27935865 NCBI chr 4:84,593,558...84,642,700
Ensembl chr 4:84,593,892...84,642,700 		JBrowse link
G Adhfe1 alcohol dehydrogenase, iron containing, 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ADHFE1 mRNA CTD PMID:27935865 NCBI chr 5:9,705,966...9,732,580
Ensembl chr 5:9,705,970...9,732,517 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing multiple interactions
decreases expression
increases expression		 ISO
EXP		 2-chloro-5-nitrobenzanilide inhibits the reaction [Pioglitazone results in increased expression of ADIPOQ mRNA]; [N-nitroso-tris-chloroethylurea co-treated with Pioglitazone] results in decreased expression of ADIPOQ mRNA; [Sodium Glutamate co-treated with Pioglitazone] results in increased expression of ADIPOQ protein; Pioglitazone promotes the reaction [Palmitates results in increased secretion of ADIPOQ protein]; PPARG protein affects the reaction [Pioglitazone results in increased expression of ADIPOQ mRNA]
Pioglitazone results in decreased expression of ADIPOQ protein
2-chloro-5-nitrobenzanilide inhibits the reaction [Pioglitazone promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased secretion of ADIPOQ protein]]; Pioglitazone promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased secretion of ADIPOQ protein]; Pioglitazone promotes the reaction [[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ADIPOQ protein]; T 0070907 inhibits the reaction [Pioglitazone promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased secretion of ADIPOQ protein]]
Pioglitazone inhibits the reaction [Dietary Fats results in decreased expression of ADIPOQ protein]; Pioglitazone inhibits the reaction [Fructose results in decreased secretion of ADIPOQ protein]
pioglitazone results in increased expression of ADIPOQ mRNA; pioglitazone results in increased expression of ADIPOQ protein		 CTD PMID:12927809 PMID:18303122 PMID:18513333 PMID:18815186 PMID:19048458 More... NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564 		JBrowse link
G Adm adrenomedullin multiple interactions ISO [pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of ADM mRNA CTD PMID:20847119 NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654 		JBrowse link
G Adora1 adenosine A1 receptor multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ADORA1 mRNA CTD PMID:27935865 NCBI chr13:45,658,872...45,695,821
Ensembl chr13:45,658,872...45,695,801 		JBrowse link
G Agbl1 AGBL carboxypeptidase 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of AGBL1 mRNA CTD PMID:27935865 NCBI chr 1:130,043,914...130,950,739
Ensembl chr 1:130,043,970...130,951,638 		JBrowse link
G Ager advanced glycosylation end product-specific receptor multiple interactions EXP Pioglitazone inhibits the reaction [Fructose results in increased expression of AGER protein] CTD PMID:25679220 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078 		JBrowse link
G Agt angiotensinogen multiple interactions EXP pioglitazone inhibits the reaction [AGT protein results in increased expression of KLF5 mRNA]; pioglitazone inhibits the reaction [AGT protein results in increased expression of KLF5 protein] CTD PMID:25874449 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977 		JBrowse link
G Agtr1a angiotensin II receptor, type 1a multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of AGTR1A mRNA CTD PMID:27935865 NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946 		JBrowse link
G Agtr2 angiotensin II receptor, type 2 multiple interactions ISO [ANGPT2 protein binds to and results in increased activity of AGTR2 protein] promotes the reaction [pioglitazone binds to and results in increased activity of PPARG protein]; [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of AGTR2 mRNA CTD PMID:15992368 PMID:27935865 NCBI chr  X:112,119,673...112,124,060
Ensembl chr  X:112,120,228...112,124,057 		JBrowse link
G Aifm3 apoptosis inducing factor, mitochondria associated 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of AIFM3 mRNA CTD PMID:27935865 NCBI chr11:83,504,859...83,523,630
Ensembl chr11:83,504,861...83,521,248 		JBrowse link
G Ajuba ajuba LIM protein multiple interactions ISO [pioglitazone co-treated with tert-Butylhydroperoxide] results in decreased expression of AJUBA mRNA CTD PMID:20847119 NCBI chr15:28,019,775...28,031,537
Ensembl chr15:28,019,778...28,030,021 		JBrowse link
G Alpk3 alpha-kinase 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ALPK3 mRNA CTD PMID:27935865 NCBI chr 1:135,014,455...135,062,294
Ensembl chr 1:135,014,499...135,062,302 		JBrowse link
G Amigo2 adhesion molecule with Ig like domain 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of AMIGO2 mRNA CTD PMID:27935865 NCBI chr 7:128,391,493...128,394,589
Ensembl chr 7:128,390,412...128,394,695 		JBrowse link
G Amotl2 angiomotin like 2 multiple interactions ISO [pioglitazone co-treated with tert-Butylhydroperoxide] results in decreased expression of AMOTL2 mRNA CTD PMID:20847119 NCBI chr 8:103,303,368...103,319,161
Ensembl chr 8:103,302,992...103,318,910 		JBrowse link
G Ampd1 adenosine monophosphate deaminase 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of AMPD1 mRNA CTD PMID:27935865 NCBI chr 2:190,598,707...190,619,938
Ensembl chr 2:190,598,700...190,619,938 		JBrowse link
G Angpt2 angiopoietin 2 multiple interactions ISO [ANGPT2 protein binds to and results in increased activity of AGTR2 protein] promotes the reaction [pioglitazone binds to and results in increased activity of PPARG protein] CTD PMID:15992368 NCBI chr16:71,088,364...71,138,805
Ensembl chr16:71,088,364...71,138,804 		JBrowse link
G Angptl2 angiopoietin-like 2 multiple interactions ISO [pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of ANGPTL2 mRNA; pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of ANGPTL2 mRNA] CTD PMID:20847119 NCBI chr 3:16,517,185...16,547,024
Ensembl chr 3:16,517,420...16,548,178 		JBrowse link
G Angptl4 angiopoietin-like 4 increases expression ISO Pioglitazone results in increased expression of ANGPTL4 mRNA CTD PMID:30031879 NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519 		JBrowse link
G Ank1 ankyrin 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ANK1 mRNA CTD PMID:27935865 NCBI chr16:68,876,294...69,054,812
Ensembl chr16:68,877,504...69,054,759 		JBrowse link
G Ankrd37 ankyrin repeat domain 37 multiple interactions ISO [pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of ANKRD37 mRNA; pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of ANKRD37 mRNA] CTD PMID:20847119 NCBI chr16:46,269,025...46,271,971
Ensembl chr16:46,268,443...46,271,963 		JBrowse link
G Ankrd63 ankyrin repeat domain 63 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ANKRD63 mRNA CTD PMID:27935865 NCBI chr 3:105,675,147...105,680,200
Ensembl chr 3:105,663,638...105,682,404 		JBrowse link
G Ano5 anoctamin 5 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ANO5 mRNA CTD PMID:27935865 NCBI chr 1:101,086,490...101,187,547
Ensembl chr 1:101,087,341...101,187,555 		JBrowse link
G Anos1 anosmin 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of WFDC17 mRNA CTD PMID:27935865 NCBI chr10:68,561,954...68,562,801
Ensembl chr10:68,561,954...68,562,801 		JBrowse link
G Aoc3 amine oxidase, copper containing 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of AOC3 mRNA CTD PMID:27935865 NCBI chr10:86,272,757...86,280,702 JBrowse link
G Ap1s2 adaptor related protein complex 1 subunit sigma 2 decreases expression ISO Pioglitazone results in decreased expression of AP1S2 mRNA CTD PMID:30031879 NCBI chr  X:30,572,746...30,598,961
Ensembl chr  X:30,572,751...30,597,262 		JBrowse link
G Apc2 APC regulator of WNT signaling pathway 2 increases expression ISO pioglitazone results in increased expression of APC2 mRNA CTD PMID:21347706 NCBI chr 7:9,392,336...9,414,364
Ensembl chr 7:9,392,336...9,414,310 		JBrowse link
G Apob apolipoprotein B decreases expression ISO pioglitazone results in decreased expression of APOB protein CTD PMID:16324916 NCBI chr 6:30,844,386...30,883,983
Ensembl chr 6:30,844,368...30,892,497 		JBrowse link
G Apoc1 apolipoprotein C1 multiple interactions ISO [Ephedrine co-treated with Caffeine co-treated with pioglitazone] results in increased expression of APOC1 protein CTD PMID:16324916 NCBI chr 1:79,347,057...79,350,340
Ensembl chr 1:79,346,136...79,350,375 		JBrowse link
G Apoc2 apolipoprotein C2 multiple interactions ISO [Ephedrine co-treated with Caffeine co-treated with pioglitazone] results in decreased expression of APOC2 protein
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of APOC2 mRNA		 CTD PMID:16324916 PMID:27935865 NCBI chr 1:79,329,429...79,334,397
Ensembl chr 1:79,329,428...79,334,476 		JBrowse link
G Apoc3 apolipoprotein C3 multiple interactions ISO [Ephedrine co-treated with Caffeine co-treated with pioglitazone] results in decreased expression of APOC3 protein CTD PMID:16324916 NCBI chr 8:46,531,478...46,533,658
Ensembl chr 8:46,531,478...46,533,583 		JBrowse link
G Apol9a apolipoprotein L 9a multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of APOL6 mRNA CTD PMID:27935865 NCBI chr 7:109,140,871...109,149,799
Ensembl chr 7:109,140,871...109,147,649 		JBrowse link
G App amyloid beta precursor protein decreases expression
multiple interactions		 ISO pioglitazone results in decreased expression of APP protein mutant form
pioglitazone inhibits the reaction [[IFNG protein co-treated with IL1B protein] results in increased metabolism of and results in increased secretion of APP protein alternative form]; pioglitazone inhibits the reaction [[IFNG protein co-treated with TNF protein] results in increased metabolism of and results in increased secretion of APP protein alternative form]		 CTD PMID:14586007 PMID:15817521 PMID:16407166 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Aqp7 aquaporin 7 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of AQP7 mRNA CTD PMID:27935865 NCBI chr 5:56,171,649...56,186,642
Ensembl chr 5:56,172,519...56,186,642 		JBrowse link
G Ar androgen receptor multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of AR mRNA CTD PMID:27935865 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Areg amphiregulin multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of AREG mRNA CTD PMID:27935865 NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535 		JBrowse link
G Armcx2 armadillo repeat containing, X-linked 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ARMCX2 mRNA CTD PMID:27935865 NCBI chr  X:97,980,662...97,985,523
Ensembl chr  X:97,980,660...97,985,552 		JBrowse link
G Art1 ADP-ribosyltransferase 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ART1 mRNA CTD PMID:27935865 NCBI chr 1:156,478,096...156,487,172
Ensembl chr 1:156,482,621...156,487,172 		JBrowse link
G Asb10 ankyrin repeat and SOCS box-containing 10 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ASB10 mRNA CTD PMID:27935865 NCBI chr 4:10,630,318...10,644,270
Ensembl chr 4:10,630,448...10,639,060 		JBrowse link
G Asb14 ankyrin repeat and SOCS box-containing 14 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ASB14 mRNA CTD PMID:27935865 NCBI chr16:2,095,567...2,123,259
Ensembl chr16:2,095,644...2,115,135 		JBrowse link
G Asb5 ankyrin repeat and SOCS box-containing 5 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ASB5 mRNA CTD PMID:27935865 NCBI chr16:37,237,869...37,305,207
Ensembl chr16:37,235,405...37,278,109 		JBrowse link
G Atf3 activating transcription factor 3 multiple interactions ISO [pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of ATF3 mRNA CTD PMID:20847119 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631 		JBrowse link
G Atp1a2 ATPase Na+/K+ transporting subunit alpha 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ATP1A2 mRNA CTD PMID:27935865 NCBI chr13:84,729,597...84,754,544
Ensembl chr13:84,729,601...84,754,544 		JBrowse link
G Atp2a1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ATP2A1 mRNA CTD PMID:27935865 NCBI chr 1:181,026,606...181,044,859
Ensembl chr 1:181,026,608...181,044,838 		JBrowse link
G Atp5f1b ATP synthase F1 subunit beta decreases expression ISO pioglitazone results in decreased expression of ATP5F1B mRNA CTD PMID:20860658 NCBI chr 7:515,454...521,858
Ensembl chr 7:515,460...567,273 		JBrowse link
G Avpr1a arginine vasopressin receptor 1A multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of AVPR1A mRNA CTD PMID:27935865 NCBI chr 7:58,114,306...58,118,230
Ensembl chr 7:58,114,284...58,122,215 		JBrowse link
G B4galnt2 beta-1,4-N-acetyl-galactosaminyl transferase 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of B4GALNT2 mRNA CTD PMID:27935865 NCBI chr10:80,801,594...80,828,005
Ensembl chr10:80,802,941...80,857,700 		JBrowse link
G B4galnt3 beta-1,4-N-acetyl-galactosaminyl transferase 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of B4GALNT3 mRNA CTD PMID:27935865 NCBI chr 4:153,410,907...153,509,019
Ensembl chr 4:153,409,004...153,509,321 		JBrowse link
G Bace1 beta-secretase 1 multiple interactions
decreases expression
decreases activity		 ISO pioglitazone inhibits the reaction [[IFNG protein co-treated with TNF protein] results in increased expression of and results in increased activity of BACE1 protein]
pioglitazone results in decreased expression of BACE1 mRNA; pioglitazone results in decreased expression of BACE1 protein
pioglitazone results in decreased activity of BACE1 protein		 CTD PMID:14586007 PMID:15817521 PMID:16407166 NCBI chr 8:46,142,060...46,166,268
Ensembl chr 8:46,142,116...46,165,876 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions EXP [naringin co-treated with Pioglitazone] inhibits the reaction [Quinolinic Acid results in increased expression of BAX mRNA]; Pioglitazone inhibits the reaction [Quinolinic Acid results in increased expression of BAX mRNA] CTD PMID:30130594 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bche butyrylcholinesterase multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of BCHE mRNA CTD PMID:27935865 NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148 		JBrowse link
G Bcl11a BAF chromatin remodeling complex subunit BCL11A decreases expression ISO Pioglitazone results in decreased expression of BCL11A mRNA CTD PMID:30031879 NCBI chr14:98,029,018...98,124,181
Ensembl chr14:98,030,461...98,124,180 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions EXP [naringin co-treated with Pioglitazone] inhibits the reaction [Quinolinic Acid results in decreased expression of BCL2 mRNA]; Pioglitazone inhibits the reaction [Quinolinic Acid results in decreased expression of BCL2 mRNA] CTD PMID:30130594 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions ISO Pioglitazone inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of BDNF protein] CTD PMID:32735850 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Bend5 BEN domain containing 5 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of BEND5 mRNA CTD PMID:27935865 NCBI chr 5:126,290,648...126,336,662
Ensembl chr 5:125,254,956...126,534,367 		JBrowse link
G Bglap bone gamma-carboxyglutamate protein multiple interactions ISO Pioglitazone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA] CTD PMID:32473317 NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495 		JBrowse link
G Bhlha15 basic helix-loop-helix family, member a15 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of BHLHA15 mRNA CTD PMID:27935865 NCBI chr12:10,420,465...10,424,641
Ensembl chr12:10,420,467...10,424,713 		JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 decreases expression ISO Pioglitazone results in decreased expression of BIRC3 mRNA CTD PMID:30031879 NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802 		JBrowse link
G Bmp6 bone morphogenetic protein 6 increases expression ISO Pioglitazone results in increased expression of BMP6 mRNA CTD PMID:32816093 NCBI chr17:26,318,121...26,469,034
Ensembl chr17:26,318,569...26,470,365 		JBrowse link
G Bpifa5 BPI fold containing family A, member 5 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of BPIFA5 mRNA CTD PMID:27935865 NCBI chr 3:142,646,103...142,652,884
Ensembl chr 3:142,646,103...142,652,883 		JBrowse link
G Bpifb1 BPI fold containing family B, member 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of BPIFB1 mRNA CTD PMID:27935865 NCBI chr 3:142,672,995...142,706,258
Ensembl chr 3:142,672,995...142,706,256 		JBrowse link
G Bsg basigin (Ok blood group) multiple interactions
decreases expression		 ISO 2-chloro-5-nitrobenzanilide inhibits the reaction [pioglitazone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BSG protein]]; pioglitazone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BSG mRNA]; pioglitazone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BSG protein]
pioglitazone results in decreased expression of BSG protein		 CTD PMID:16860414 PMID:17007354 PMID:17055343 NCBI chr 7:9,993,170...10,000,387
Ensembl chr 7:9,993,170...10,000,387 		JBrowse link
G Btn2a2 butyrophilin, subfamily 2, member A2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of BTN2A2 mRNA CTD PMID:27935865 NCBI chr17:41,620,807...41,632,621
Ensembl chr17:41,620,839...41,632,618 		JBrowse link
G Bzw1 basic leucine zipper and W2 domains 1 multiple interactions ISO [pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of BZW1 mRNA; pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of BZW1 mRNA] CTD PMID:20847119 NCBI chr 9:59,930,672...59,944,468
Ensembl chr 9:59,930,744...59,944,430 		JBrowse link
G C1qtnf7 C1q and TNF related 7 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of C1QTNF7 mRNA CTD PMID:27935865 NCBI chr14:67,467,888...67,580,477
Ensembl chr14:67,468,014...67,580,410 		JBrowse link
G C2H1orf54 chromosome 2 C1orf54 homolog decreases expression ISO Pioglitazone results in decreased expression of C1ORF54 mRNA CTD PMID:30031879 NCBI chr 2:183,424,989...183,434,773
Ensembl chr 2:183,424,984...183,435,089 		JBrowse link
G C4a complement C4A multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of C4A mRNA CTD PMID:27935865 NCBI chr20:4,005,731...4,020,083
Ensembl chr20:4,005,731...4,020,080 		JBrowse link
G C5ar1 complement C5a receptor 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of C5AR1 mRNA CTD PMID:27935865 NCBI chr 1:76,948,622...76,959,826 JBrowse link
G Ca3 carbonic anhydrase 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CAR3 mRNA CTD PMID:27935865 NCBI chr 2:86,770,418...86,780,011
Ensembl chr 2:86,770,420...86,784,280 		JBrowse link
G Cabcoco1 ciliary associated calcium binding coiled-coil 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CABCOCO1 mRNA CTD PMID:27935865 NCBI chr20:20,058,492...20,167,973
Ensembl chr20:20,058,454...20,167,725 		JBrowse link
G Cacna1c calcium voltage-gated channel subunit alpha1 C multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CACNA1C mRNA CTD PMID:27935865 NCBI chr 4:151,764,138...152,379,454
Ensembl chr 4:151,764,138...152,379,648 		JBrowse link
G Cacna1s calcium voltage-gated channel subunit alpha1 S multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CACNA1S mRNA CTD PMID:27935865 NCBI chr13:47,493,949...47,564,194
Ensembl chr13:47,493,949...47,564,318 		JBrowse link
G Cacna2d3 calcium voltage-gated channel auxiliary subunit alpha2delta 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CACNA2D3 mRNA CTD PMID:27935865 NCBI chr16:4,098,439...4,912,498
Ensembl chr16:4,098,445...4,912,351 		JBrowse link
G Cadm2 cell adhesion molecule 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CADM2 mRNA CTD PMID:27935865 NCBI chr11:4,548,367...5,525,420
Ensembl chr11:4,555,159...5,525,400 		JBrowse link
G Calhm5 calcium homeostasis modulator family member 5 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CALHM5 mRNA CTD PMID:27935865 NCBI chr20:26,066,270...26,072,348
Ensembl chr20:26,066,242...26,072,272 		JBrowse link
G Casp3 caspase 3 multiple interactions ISO
EXP		 pioglitazone inhibits the reaction [Galactose results in increased activity of CASP3 protein]
[naringin co-treated with Pioglitazone] inhibits the reaction [Quinolinic Acid results in increased expression of CASP3 mRNA]; Pioglitazone inhibits the reaction [Quinolinic Acid results in increased expression of CASP3 mRNA]		 CTD PMID:23795773 PMID:30130594 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casq1 calsequestrin 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CASQ1 mRNA CTD PMID:27935865 NCBI chr13:84,670,648...84,680,339
Ensembl chr13:84,670,649...84,680,339 		JBrowse link
G Cat catalase multiple interactions EXP
ISO		 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [Pioglitazone inhibits the reaction [Quinolinic Acid results in decreased activity of CAT protein]]; Pioglitazone inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased activity of CAT protein]; Pioglitazone inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of CAT protein]; Pioglitazone inhibits the reaction [Quinolinic Acid results in decreased activity of CAT protein]; Pioglitazone inhibits the reaction [Streptozocin results in decreased activity of CAT protein]
Pioglitazone inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased activity of CAT protein]		 CTD PMID:20450929 PMID:27350165 PMID:29233026 PMID:29247773 PMID:32735850 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Cav1 caveolin 1 affects expression ISO pioglitazone affects the expression of CAV1 protein CTD PMID:17961437 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705 		JBrowse link
G Cav3 caveolin 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CAV3 mRNA CTD PMID:27935865 NCBI chr 4:145,582,168...145,598,142
Ensembl chr 4:145,582,060...145,598,137 		JBrowse link
G Ccdc159 coiled-coil domain containing 159 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CCDC159 mRNA CTD PMID:27935865 NCBI chr 8:20,457,905...20,467,232
Ensembl chr 8:20,457,909...20,466,562 		JBrowse link
G Ccdc85a coiled-coil domain containing 85A multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CCDC85A mRNA CTD PMID:27935865 NCBI chr14:102,126,574...102,359,207
Ensembl chr14:102,129,029...102,359,058 		JBrowse link
G Ccl11 C-C motif chemokine ligand 11 multiple interactions ISO pioglitazone inhibits the reaction [Toluene 2,4-Diisocyanate results in increased expression of CCL11 protein] CTD PMID:17015710 NCBI chr10:67,028,328...67,032,929
Ensembl chr10:67,028,328...67,032,926 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO [Pioglitazone co-treated with tert-Butylhydroperoxide] results in decreased expression of CCL2 mRNA; Pioglitazone inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of CCL2 mRNA		 CTD PMID:20847119 PMID:27935865 PMID:32613381 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 multiple interactions
decreases expression		 ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of CCL3 mRNA
Pioglitazone results in decreased expression of CCL3 mRNA		 CTD PMID:27935865 PMID:30031879 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 multiple interactions
decreases response to substance		 ISO pioglitazone inhibits the reaction [Toluene 2,4-Diisocyanate results in increased expression of CCL5 protein]
pioglitazone results in decreased susceptibility to CCL5 protein		 CTD PMID:17015710 PMID:18158351 NCBI chr10:68,322,826...68,327,365
Ensembl chr10:68,322,829...68,327,377 		JBrowse link
G Ccl7 C-C motif chemokine ligand 7 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of CCL7 mRNA CTD PMID:27935865 NCBI chr10:67,016,446...67,018,296
Ensembl chr10:67,016,446...67,018,303 		JBrowse link
G Ccn2 cellular communication network factor 2 multiple interactions ISO
EXP		 [Pioglitazone co-treated with tert-Butylhydroperoxide] results in decreased expression of CCN2 mRNA; Pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in decreased expression of CCN2 mRNA]
Pioglitazone affects the reaction [Carbon Tetrachloride results in increased expression of CCN2 mRNA]		 CTD PMID:16484506 PMID:20847119 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734 		JBrowse link
G Ccna1 cyclin A1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CCNA1 mRNA CTD PMID:27935865 NCBI chr 2:139,231,738...139,278,066
Ensembl chr 2:139,201,074...139,243,157 		JBrowse link
G Ccna2 cyclin A2 decreases expression ISO pioglitazone results in decreased expression of CCNA2 protein CTD PMID:15729575 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577 		JBrowse link
G Ccnb1 cyclin B1 decreases expression ISO pioglitazone results in decreased expression of CCNB1 protein CTD PMID:15729575 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172 		JBrowse link
G Ccnd1 cyclin D1 decreases expression
multiple interactions		 ISO pioglitazone results in decreased expression of CCND1 mRNA; pioglitazone results in decreased expression of CCND1 protein
pioglitazone inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased expression of CCND1 protein]
Pioglitazone results in decreased expression of CCND1 mRNA		 CTD PMID:17077279 PMID:26643070 PMID:30031879 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Ccnd3 cyclin D3 decreases expression ISO pioglitazone results in decreased expression of CCND3 protein CTD PMID:15729575 NCBI chr 9:13,394,161...13,400,341
Ensembl chr 9:13,394,169...13,489,371 		JBrowse link
G Ccne1 cyclin E1 decreases expression ISO pioglitazone results in decreased expression of CCNE1 protein CTD PMID:15729575 NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101 		JBrowse link
G Ccno cyclin O multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CCNO mRNA CTD PMID:27935865 NCBI chr 2:44,630,640...44,633,914
Ensembl chr 2:44,626,369...44,633,914 		JBrowse link
G Cd36 CD36 molecule increases expression
multiple interactions		 ISO
EXP		 Pioglitazone results in increased expression of CD36 mRNA; Pioglitazone results in increased expression of CD36 protein
Pioglitazone inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; PPARG protein affects the reaction [Pioglitazone results in increased expression of CD36 protein]
[pioglitazone co-treated with Buthionine Sulfoximine] results in increased expression of CD36 mRNA
pioglitazone results in increased expression of CD36 mRNA		 CTD PMID:15381068 PMID:16484506 PMID:17143554 PMID:19048458 PMID:20723549 More... NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903 		JBrowse link
G Cd84 CD84 molecule decreases expression ISO Pioglitazone results in decreased expression of CD84 mRNA CTD PMID:30031879 NCBI chr13:84,327,580...84,367,153
Ensembl chr13:84,327,553...84,362,076 		JBrowse link
G Cdc20b cell division cycle 20B multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CDC20B mRNA CTD PMID:27935865 NCBI chr 2:44,688,349...44,738,056 JBrowse link
G Cdc42 cell division cycle 42 decreases expression ISO Pioglitazone results in decreased expression of CDC42 mRNA CTD PMID:32589349 NCBI chr 5:149,555,069...149,593,239
Ensembl chr 5:149,553,724...149,593,111 		JBrowse link
G Cdk2 cyclin dependent kinase 2 decreases expression ISO pioglitazone results in decreased expression of CDK2 protein CTD PMID:15729575 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403 		JBrowse link
G Cdkl1 cyclin dependent kinase like 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CDKL1 mRNA CTD PMID:27935865 NCBI chr 6:88,224,154...88,273,434
Ensembl chr 6:88,224,143...88,270,276 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
decreases expression		 EXP
ISO		 pioglitazone inhibits the reaction [2-Acetylaminofluorene inhibits the reaction [Diethylnitrosamine results in decreased expression of CDKN1A protein]]; pioglitazone promotes the reaction [Diethylnitrosamine results in decreased expression of CDKN1A protein]
Melatonin promotes the reaction [Pioglitazone inhibits the reaction [Indican results in increased expression of CDKN1A protein]]; Pioglitazone inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased expression of CDKN1A protein]; Pioglitazone inhibits the reaction [Indican results in increased expression of CDKN1A protein]; Pioglitazone promotes the reaction [Melatonin inhibits the reaction [Indican results in increased expression of CDKN1A protein]]; PRNP protein promotes the reaction [Melatonin promotes the reaction [Pioglitazone inhibits the reaction [Indican results in increased expression of CDKN1A protein]]]; PRNP protein promotes the reaction [Pioglitazone promotes the reaction [Melatonin inhibits the reaction [Indican results in increased expression of CDKN1A protein]]]
pioglitazone results in decreased expression of CDKN1A protein		 CTD PMID:15729575 PMID:17582756 PMID:26643070 PMID:29734669 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B multiple interactions
increases expression		 EXP
ISO		 pioglitazone inhibits the reaction [2-Acetylaminofluorene promotes the reaction [Diethylnitrosamine results in decreased expression of CDKN1B protein]]; pioglitazone promotes the reaction [Diethylnitrosamine results in decreased expression of CDKN1B protein]
pioglitazone inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased degradation of CDKN1B protein]; PRKAA1 protein affects the reaction [pioglitazone results in increased expression of CDKN1B protein]		 CTD PMID:17582756 PMID:26643070 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982 		JBrowse link
G Cdkn1c cyclin-dependent kinase inhibitor 1C multiple interactions ISO [pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of CDKN1C mRNA CTD PMID:20847119 NCBI chr 1:198,655,394...198,658,097
Ensembl chr 1:198,655,407...198,658,048 		JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha increases expression ISO pioglitazone results in increased expression of CEBPA mRNA CTD PMID:28242381 NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412 		JBrowse link
G Cemip cell migration inducing hyaluronidase 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of CEMIP mRNA CTD PMID:27935865 NCBI chr 1:137,906,921...138,062,430
Ensembl chr 1:137,908,920...138,062,415 		JBrowse link
G Ces1d carboxylesterase 1D increases expression ISO pioglitazone results in increased expression of CES1 mRNA CTD PMID:15381068 NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035 		JBrowse link
G Cfd complement factor D multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CFD mRNA CTD PMID:27935865 NCBI chr 7:9,813,148...9,814,871
Ensembl chr 7:9,813,150...9,815,053 		JBrowse link
G Chchd6 coiled-coil-helix-coiled-coil-helix domain containing 6 decreases expression ISO Pioglitazone results in decreased expression of CHCHD6 mRNA CTD PMID:30031879 NCBI chr 4:121,803,501...122,024,209
Ensembl chr 4:121,792,717...122,024,216 		JBrowse link
G Chi3l1 chitinase 3 like 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of CHIL1 mRNA CTD PMID:27935865 NCBI chr13:45,641,802...45,649,787
Ensembl chr13:45,641,802...45,649,787 		JBrowse link
G Chit1 chitinase 1 decreases expression ISO Pioglitazone results in decreased expression of CHIT1 mRNA CTD PMID:30031879 NCBI chr13:45,565,841...45,613,593
Ensembl chr13:45,593,845...45,613,592 		JBrowse link
G Chp2 calcineurin-like EF hand protein 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CHP2 mRNA CTD PMID:27935865 NCBI chr 1:176,757,945...176,772,443
Ensembl chr 1:176,757,876...176,772,139 		JBrowse link
G Chrm1 cholinergic receptor, muscarinic 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CHRM1 mRNA CTD PMID:27935865 NCBI chr 1:205,567,046...205,583,001
Ensembl chr 1:205,567,220...205,582,356 		JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CHRM2 mRNA CTD PMID:27935865 NCBI chr 4:65,015,408...65,149,104
Ensembl chr 4:65,014,144...65,149,103 		JBrowse link
G Chrna1 cholinergic receptor nicotinic alpha 1 subunit multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CHRNA1 mRNA CTD PMID:27935865 NCBI chr 3:58,454,763...58,469,832
Ensembl chr 3:58,454,744...58,469,840 		JBrowse link
G Chrne cholinergic receptor nicotinic epsilon subunit multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CHRNE mRNA CTD PMID:27935865 NCBI chr10:55,331,211...55,339,923
Ensembl chr10:55,331,212...55,335,530 		JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex multiple interactions ISO [Metformin co-treated with Pioglitazone] results in decreased expression of CHUK mRNA CTD PMID:32589349 NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065 		JBrowse link
G Cidec cell death-inducing DFFA-like effector c multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CIDEC mRNA CTD PMID:27935865 NCBI chr 4:146,569,288...146,582,173
Ensembl chr 4:146,569,289...146,582,173 		JBrowse link
G Ckm creatine kinase, M-type multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CKM mRNA CTD PMID:27935865 NCBI chr 1:79,061,390...79,071,721
Ensembl chr 1:79,061,456...79,071,720 		JBrowse link
G Ckmt2 creatine kinase, mitochondrial 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CKMT2 mRNA CTD PMID:27935865 NCBI chr 2:23,079,920...23,110,518
Ensembl chr 2:23,079,918...23,110,430 		JBrowse link
G Clec14a C-type lectin domain containing 14A multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CLEC14A mRNA CTD PMID:27935865 NCBI chr 6:75,881,470...75,884,612
Ensembl chr 6:75,881,473...75,884,612 		JBrowse link
G Clec1a C-type lectin domain family 1, member A increases expression ISO Pioglitazone results in increased expression of CLEC1A mRNA CTD PMID:30031879 NCBI chr 4:162,875,360...162,902,571
Ensembl chr 4:162,877,346...162,901,247 		JBrowse link
G Clec4a3 C-type lectin domain family 4, member A3 decreases expression ISO Pioglitazone results in decreased expression of CLEC4A mRNA CTD PMID:30031879 NCBI chr 4:156,214,030...156,224,818
Ensembl chr 4:156,214,718...156,224,817 		JBrowse link
G Clec4d C-type lectin domain family 4, member D multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of CLEC4D mRNA CTD PMID:27935865 NCBI chr 4:156,589,591...156,598,969
Ensembl chr 4:156,589,792...156,598,848 		JBrowse link
G Clec4e C-type lectin domain family 4, member E multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of CLEC4E mRNA CTD PMID:27935865 NCBI chr 4:156,606,927...156,612,911
Ensembl chr 4:156,607,614...156,612,767 		JBrowse link
G Clstn3 calsyntenin 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CLSTN3 mRNA CTD PMID:27935865 NCBI chr 4:157,331,494...157,364,769
Ensembl chr 4:157,331,494...157,364,769 		JBrowse link
G Cmya5 cardiomyopathy associated 5 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CMYA5 mRNA CTD PMID:27935865 NCBI chr 2:24,279,520...24,378,253
Ensembl chr 2:24,279,528...24,378,364 		JBrowse link
G Cnga3 cyclic nucleotide gated channel subunit alpha 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of CNGA3 mRNA CTD PMID:27935865 NCBI chr 9:39,447,532...39,497,883
Ensembl chr 9:39,448,034...39,493,183 		JBrowse link
G Cnn1 calponin 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CNN1 mRNA CTD PMID:27935865 NCBI chr 8:20,632,434...20,641,097
Ensembl chr 8:20,632,338...20,641,098 		JBrowse link
G Cnrip1 cannabinoid receptor interacting protein 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CNRIP1 mRNA CTD PMID:27935865 NCBI chr14:91,463,046...91,492,736
Ensembl chr14:91,462,647...91,492,735 		JBrowse link
G Cntd1 cyclin N-terminal domain containing 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CNTD1 mRNA CTD PMID:27935865 NCBI chr10:86,221,430...86,231,812 JBrowse link
G Cog8 component of oligomeric golgi complex 8 multiple interactions ISO [pioglitazone co-treated with tert-Butylhydroperoxide] results in decreased expression of COG8 mRNA CTD PMID:20847119 NCBI chr19:34,951,625...34,962,377
Ensembl chr19:34,951,627...34,962,397 		JBrowse link
G Col6a5 collagen type VI alpha 5 chain multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of COL6A5 mRNA CTD PMID:27935865 NCBI chr 8:106,483,806...106,584,114
Ensembl chr 8:106,483,799...106,584,113 		JBrowse link
G Coro6 coronin 6 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CORO6 mRNA CTD PMID:27935865 NCBI chr10:62,311,552...62,319,659
Ensembl chr10:62,311,660...62,319,659 		JBrowse link
G Cox6a2 cytochrome c oxidase subunit 6A2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of COX6A2 mRNA CTD PMID:27935865 NCBI chr 1:182,788,528...182,790,746
Ensembl chr 1:182,788,528...182,789,274 		JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A multiple interactions ISO Pioglitazone affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA] CTD PMID:32613381 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055 		JBrowse link
G Cpt1b carnitine palmitoyltransferase 1B increases expression ISO pioglitazone results in increased expression of CPT1B mRNA CTD PMID:20723549 NCBI chr 7:120,491,354...120,500,833
Ensembl chr 7:120,491,354...120,500,404 		JBrowse link
G Cpxm1 carboxypeptidase X (M14 family), member 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CPXM1 mRNA CTD PMID:27935865 NCBI chr 3:117,588,532...117,595,330
Ensembl chr 3:117,588,532...117,595,330 		JBrowse link
G Cpz carboxypeptidase Z multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CPZ mRNA CTD PMID:27935865 NCBI chr14:75,223,692...75,246,946
Ensembl chr14:75,223,605...75,246,945 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions ISO Pioglitazone inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of CREB1 protein] CTD PMID:32735850 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Crh corticotropin releasing hormone increases expression ISO Pioglitazone results in increased expression of CRH mRNA CTD PMID:30031879 NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919 		JBrowse link
G Crhr2 corticotropin releasing hormone receptor 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CRHR2 mRNA CTD PMID:27935865 NCBI chr 4:84,222,897...84,265,924
Ensembl chr 4:84,224,002...84,265,904 		JBrowse link
G Crispld1 cysteine-rich secretory protein LCCL domain containing 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CRISPLD1 mRNA CTD PMID:27935865 NCBI chr 5:1,267,347...1,314,926
Ensembl chr 5:1,274,647...1,314,926 		JBrowse link
G Crp C-reactive protein affects expression
decreases expression		 EXP
ISO		 pioglitazone affects the expression of CRP protein
Pioglitazone results in decreased expression of CRP protein		 CTD PMID:28705172 PMID:28744220 NCBI chr13:85,131,635...85,175,179
Ensembl chr13:85,124,977...85,175,178 		JBrowse link
G Cryab crystallin, alpha B multiple interactions ISO [pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of CRYAB mRNA; pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of CRYAB mRNA] CTD PMID:20847119 NCBI chr 8:51,093,441...51,099,161
Ensembl chr 8:51,093,441...51,099,157 		JBrowse link
G Crym crystallin, mu multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CRYM mRNA CTD PMID:27935865 NCBI chr 1:174,560,423...174,575,660
Ensembl chr 1:174,560,416...174,575,633 		JBrowse link
G Csn1s1 casein alpha s1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of CSN1S1 mRNA CTD PMID:27935865 NCBI chr14:20,343,620...20,359,614
Ensembl chr14:20,343,619...20,359,614 		JBrowse link
G Csrp3 cysteine and glycine rich protein 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CSRP3 mRNA CTD PMID:27935865 NCBI chr 1:98,528,067...98,546,647
Ensembl chr 1:98,528,068...98,546,653 		JBrowse link
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of CTLA4 mRNA CTD PMID:27935865 NCBI chr 9:62,318,874...62,325,978
Ensembl chr 9:62,319,312...62,324,963 		JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions ISO [pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of CTNNB1 mRNA CTD PMID:20847119 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 decreases response to substance
multiple interactions		 ISO pioglitazone results in decreased susceptibility to CXCL12 protein
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CXCL12 mRNA
pioglitazone inhibits the reaction [CXCL12 protein affects the localization of ICAM3 protein]		 CTD PMID:18158351 PMID:27935865 NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168 		JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of CXCL2 mRNA; [pioglitazone co-treated with Buthionine Sulfoximine] results in increased expression of CXCL2 mRNA CTD PMID:27935865 PMID:28263783 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075 		JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of CXCL3 mRNA CTD PMID:27935865 NCBI chr14:17,270,146...17,289,458
Ensembl chr14:17,270,146...17,289,511 		JBrowse link
G Cxcl6 C-X-C motif chemokine ligand 6 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with Pioglitazone] results in increased expression of CXCL5 mRNA CTD PMID:27935865 NCBI chr14:17,310,089...17,312,303
Ensembl chr14:17,310,426...17,313,093 		JBrowse link
G Cxcr3 C-X-C motif chemokine receptor 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CXCR3 mRNA CTD PMID:27935865 NCBI chr  X:66,844,318...66,846,969
Ensembl chr  X:66,844,318...66,846,969 		JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 multiple interactions ISO [pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of CXCR4 mRNA CTD PMID:20847119 NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883 		JBrowse link
G Cyba cytochrome b-245 alpha chain decreases expression
affects activity		 ISO pioglitazone results in decreased expression of CYBA mRNA
pioglitazone affects the activity of CYBA protein		 CTD PMID:11172467 PMID:21962020 NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721 		JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 multiple interactions
decreases expression
decreases activity		 ISO pioglitazone inhibits the reaction [2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one results in increased activity of CYP17A1 protein]; pioglitazone inhibits the reaction [2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one results in increased expression of CYP17A1 mRNA]
pioglitazone results in decreased expression of CYP17A1 mRNA
pioglitazone results in decreased activity of CYP17A1 protein		 CTD PMID:15072549 PMID:17138841 NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573 		JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 increases expression EXP
ISO		 pioglitazone results in increased expression of CYP2B1 mRNA
Pioglitazone results in increased expression of CYP2B10 mRNA		 CTD PMID:16597547 PMID:28541575 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases expression ISO pioglitazone results in increased expression of CYP2B6 protein CTD PMID:12642470 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143 		JBrowse link
G Cyp2c24 cytochrome P450, family 2, subfamily c, polypeptide 24 increases expression ISO Pioglitazone results in increased expression of CYP2C55 mRNA CTD PMID:28541575 NCBI chr 1:236,873,967...236,936,238
Ensembl chr 1:236,873,967...236,936,238 		JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 multiple interactions
increases expression
decreases activity
affects metabolic processing		 ISO Gemfibrozil inhibits the reaction [CYP2C8 protein affects the metabolism of pioglitazone]
Pioglitazone results in increased expression of CYP2C8 mRNA
pioglitazone results in decreased activity of CYP2C8 protein		 CTD PMID:12642470 PMID:15900286 PMID:31233785
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CYP2E1 mRNA CTD PMID:27935865 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Cyp2g1 cytochrome P450, family 2, subfamily g, polypeptide 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CYP2G1 mRNA CTD PMID:27935865 NCBI chr 1:82,145,635...82,156,862
Ensembl chr 1:82,145,073...82,156,828 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions
decreases activity
affects metabolic processing
increases expression		 EXP
ISO		 pioglitazone inhibits the reaction [Endotoxins results in decreased expression of CYP3A2 protein]
Pioglitazone results in decreased activity of CYP3A4 protein
CYP3A4 protein affects the metabolism of Pioglitazone
Pioglitazone results in increased expression of CYP3A4 mRNA; Pioglitazone results in increased expression of CYP3A4 protein
[Pioglitazone results in increased expression of CYP3A4 protein] which results in decreased abundance of Ethinyl Estradiol; [Pioglitazone results in increased expression of CYP3A4 protein] which results in decreased abundance of Midazolam; Pioglitazone results in increased expression of and results in increased activity of CYP3A4 protein		 CTD PMID:12642470 PMID:15364003 PMID:15860655 PMID:15900286 PMID:16837568 More... NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 increases expression EXP Pioglitazone results in increased expression of CYP3A23-3A1 mRNA CTD PMID:16597547 NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030 		JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 multiple interactions
increases expression		 ISO pioglitazone promotes the reaction [U 0126 results in increased expression of CYP7A1 mRNA]; U 0126 promotes the reaction [pioglitazone results in increased expression of CYP7A1 mRNA] CTD PMID:22593575 NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688 		JBrowse link
G Dcaf12l1 DDB1 and CUL4 associated factor 12-like 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of DCAF12L1 mRNA CTD PMID:27935865 NCBI chr  X:123,695,286...123,698,905
Ensembl chr  X:123,695,286...123,698,905 		JBrowse link
G Dcx doublecortin multiple interactions ISO Pioglitazone inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of DCX protein] CTD PMID:32735850 NCBI chr  X:107,430,767...107,573,612
Ensembl chr  X:107,430,767...107,507,476 		JBrowse link
G Ddah1 dimethylarginine dimethylaminohydrolase 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of DDAH1 mRNA CTD PMID:27935865 NCBI chr 2:234,667,499...234,800,322
Ensembl chr 2:234,667,491...234,799,339 		JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 multiple interactions
increases expression		 ISO [Metformin co-treated with Pioglitazone] results in increased expression of DDIT4 mRNA
Pioglitazone results in increased expression of DDIT4 mRNA		 CTD PMID:32589349 NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105 		JBrowse link
G Ddit4l DNA-damage-inducible transcript 4-like multiple interactions
increases expression		 ISO [Metformin co-treated with Pioglitazone] results in increased expression of DDIT4L mRNA
Pioglitazone results in increased expression of DDIT4L mRNA		 CTD PMID:32589349 NCBI chr 2:226,128,273...226,131,044
Ensembl chr 2:226,128,276...226,131,375 		JBrowse link
G Depp1 DEPP1, autophagy regulator multiple interactions ISO [pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of DEPP1 mRNA; pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of DEPP1 mRNA] CTD PMID:20847119 NCBI chr 4:149,910,794...149,913,013
Ensembl chr 4:149,910,779...149,914,542 		JBrowse link
G Deptor DEP domain containing MTOR-interacting protein multiple interactions ISO [Metformin co-treated with Pioglitazone] results in decreased expression of DEPTOR mRNA CTD PMID:32589349 NCBI chr 7:86,514,859...86,668,817
Ensembl chr 7:86,514,988...86,667,773 		JBrowse link
G Derl3 derlin 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of DERL3 mRNA CTD PMID:27935865 NCBI chr20:12,754,490...12,768,454
Ensembl chr20:12,763,543...12,767,027 		JBrowse link
G Des desmin multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of DES mRNA CTD PMID:27935865 NCBI chr 9:76,850,979...76,858,695
Ensembl chr 9:76,850,982...76,858,699 		JBrowse link
G Deup1 deuterosome assembly protein 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of DEUP1 mRNA CTD PMID:27935865 NCBI chr 8:12,380,300...12,442,649
Ensembl chr 8:12,380,302...12,442,199 		JBrowse link
G Dgat1 diacylglycerol O-acyltransferase 1 increases expression ISO pioglitazone results in increased expression of DGAT1 mRNA CTD PMID:20723549 NCBI chr 7:108,223,860...108,235,413
Ensembl chr 7:108,218,524...108,234,299 		JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 increases expression ISO pioglitazone results in increased expression of DGAT2 mRNA CTD PMID:20723549 NCBI chr 1:153,454,078...153,484,432
Ensembl chr 1:153,454,080...153,484,428 		JBrowse link
G Dhrs7c dehydrogenase/reductase 7C multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of DHRS7C mRNA CTD PMID:27935865 NCBI chr10:52,495,262...52,513,338
Ensembl chr10:52,495,262...52,513,338 		JBrowse link
G Dio2 iodothyronine deiodinase 2 increases activity
increases expression
multiple interactions		 ISO pioglitazone results in increased activity of DIO2 protein
pioglitazone results in increased expression of DIO2 mRNA
PPARG protein promotes the reaction [pioglitazone results in increased activity of DIO2 protein]		 CTD PMID:19036883 NCBI chr 6:109,665,523...109,679,809
Ensembl chr 6:109,665,523...109,679,809 		JBrowse link
G Dio3 iodothyronine deiodinase 3 decreases activity ISO pioglitazone results in decreased activity of DIO3 protein CTD PMID:19036883 NCBI chr 6:129,285,747...129,287,608
Ensembl chr 6:129,285,749...129,286,660 		JBrowse link
G Dlg1 discs large MAGUK scaffold protein 1 multiple interactions ISO pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of DLG1 mRNA] CTD PMID:20847119 NCBI chr11:68,911,883...69,103,230
Ensembl chr11:68,911,883...69,102,689 		JBrowse link
G Dmbt1 deleted in malignant brain tumors 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of DMBT1 mRNA CTD PMID:27935865 NCBI chr 1:185,617,469...185,696,476
Ensembl chr 1:185,617,294...185,696,478 		JBrowse link
G Dnaaf2 dynein, axonemal, assembly factor 2 multiple interactions ISO [pioglitazone co-treated with tert-Butylhydroperoxide] results in decreased expression of DNAAF2 mRNA; pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in decreased expression of DNAAF2 mRNA] CTD PMID:20847119 NCBI chr 6:87,661,101...87,670,267
Ensembl chr 6:87,660,821...87,670,199 		JBrowse link
G Dnah8 dynein, axonemal, heavy chain 8 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of DNAH8 mRNA CTD PMID:27935865 NCBI chr20:8,692,939...8,946,780
Ensembl chr20:8,692,963...8,946,772 		JBrowse link
G Dner delta/notch-like EGF repeat containing multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of DNER mRNA CTD PMID:27935865 NCBI chr 9:85,586,985...85,902,820
Ensembl chr 9:85,586,987...85,902,637 		JBrowse link
G Dpt dermatopontin multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of DPT mRNA CTD PMID:27935865 NCBI chr13:77,122,926...77,151,646
Ensembl chr13:77,123,115...77,151,639 		JBrowse link
G Dpy19l2 dpy-19 like 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of DPY19L2 mRNA CTD PMID:27935865 NCBI chr 8:23,062,592...23,181,817
Ensembl chr 8:23,063,115...23,181,798 		JBrowse link
G Drd1 dopamine receptor D1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of DRD1 mRNA CTD PMID:27935865 NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002 		JBrowse link
G Dusp10 dual specificity phosphatase 10 multiple interactions ISO [pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of DUSP10 mRNA CTD PMID:20847119 NCBI chr13:95,613,716...95,651,716
Ensembl chr13:95,614,292...95,651,716 		JBrowse link
G Dusp26 dual specificity phosphatase 26 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of DUSP26 mRNA CTD PMID:27935865 NCBI chr16:61,041,784...61,049,319
Ensembl chr16:61,041,792...61,049,051 		JBrowse link
G Eddm3b epididymal protein 3B multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with Pioglitazone] results in decreased expression of EDDM3B mRNA CTD PMID:27935865 NCBI chr15:24,343,835...24,346,774
Ensembl chr15:24,345,573...24,346,025 		JBrowse link
G Eef1a2 eukaryotic translation elongation factor 1 alpha 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of EEF1A2 mRNA CTD PMID:27935865 NCBI chr 3:168,265,893...168,275,071
Ensembl chr 3:168,195,357...168,275,071 		JBrowse link
G Egf epidermal growth factor multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of EGF mRNA CTD PMID:27935865 NCBI chr 2:218,219,408...218,302,370
Ensembl chr 2:218,219,415...218,302,064 		JBrowse link
G Egflam EGF-like, fibronectin type III and laminin G domains multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of EGFLAM mRNA CTD PMID:27935865 NCBI chr 2:56,301,945...56,476,665
Ensembl chr 2:56,302,566...56,476,298 		JBrowse link
G Eif4e eukaryotic translation initiation factor 4E multiple interactions ISO [Metformin co-treated with Pioglitazone] results in decreased expression of EIF4E mRNA CTD PMID:32589349 NCBI chr 2:227,066,519...227,099,261
Ensembl chr 2:227,066,673...227,098,683 		JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 multiple interactions
increases expression
decreases phosphorylation		 ISO pioglitazone inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased expression of EIF4EBP1 protein]
Pioglitazone results in increased expression of EIF4EBP1 mRNA
pioglitazone results in decreased phosphorylation of EIF4EBP1 protein		 CTD PMID:26643070 PMID:32589349 NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984 		JBrowse link
G Eif4ebp2 eukaryotic translation initiation factor 4E binding protein 2 increases expression ISO Pioglitazone results in increased expression of EIF4EBP2 mRNA CTD PMID:32589349 NCBI chr20:29,379,444...29,400,131
Ensembl chr20:29,382,668...29,399,946 		JBrowse link
G Eif5a eukaryotic translation initiation factor 5A increases expression ISO pioglitazone results in increased expression of EIF5A mRNA CTD PMID:21347706 NCBI chr10:54,640,104...54,644,845
Ensembl chr10:54,640,024...54,644,656 		JBrowse link
G Elovl4 ELOVL fatty acid elongase 4 increases expression ISO Pioglitazone results in increased expression of ELOVL4 mRNA CTD PMID:30031879 NCBI chr 8:84,702,916...84,729,466
Ensembl chr 8:84,702,362...84,729,697 		JBrowse link
G Eno3 enolase 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ENO3 mRNA CTD PMID:27935865 NCBI chr10:55,370,531...55,375,921
Ensembl chr10:55,366,975...55,375,921 		JBrowse link
G Epgn epithelial mitogen multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of EPGN mRNA CTD PMID:27935865 NCBI chr14:17,076,774...17,084,806
Ensembl chr14:17,076,774...17,084,806 		JBrowse link
G Epha3 Eph receptor A3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of EPHA3 mRNA CTD PMID:27935865 NCBI chr11:1,138,485...1,474,102
Ensembl chr11:1,140,985...1,473,900 		JBrowse link
G Epha5 EPH receptor A5 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of EPHA5 mRNA CTD PMID:27935865 NCBI chr14:23,653,393...24,020,135
Ensembl chr14:23,653,393...24,017,317 		JBrowse link
G Epyc epiphycan multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of EPYC mRNA CTD PMID:27935865 NCBI chr 7:32,436,620...32,474,326
Ensembl chr 7:32,436,620...32,474,135 		JBrowse link
G Erbin erbb2 interacting protein multiple interactions ISO pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of ERBIN mRNA] CTD PMID:20847119 NCBI chr 2:34,926,962...35,028,440
Ensembl chr 2:34,928,863...35,027,852 		JBrowse link
G Ereg epiregulin increases expression ISO Pioglitazone results in increased expression of EREG mRNA CTD PMID:32816093 NCBI chr14:17,027,287...17,041,062
Ensembl chr14:17,027,287...17,041,062 		JBrowse link
G F10 coagulation factor X multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of F10 mRNA CTD PMID:27935865 NCBI chr16:76,468,834...76,488,141
Ensembl chr16:76,468,838...76,488,141 		JBrowse link
G Fabp3 fatty acid binding protein 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of FABP3 mRNA CTD PMID:27935865 NCBI chr 5:142,651,962...142,658,707
Ensembl chr 5:142,651,956...142,658,718 		JBrowse link
G Fabp4 fatty acid binding protein 4 multiple interactions
increases expression		 ISO [pioglitazone co-treated with Tretinoin] results in increased expression of FABP4 mRNA
Pioglitazone results in increased expression of FABP4 mRNA
pioglitazone results in increased expression of FABP4 mRNA
Pioglitazone promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FABP4 mRNA]; Pioglitazone promotes the reaction [[Dexamethasone co-treated with INS protein co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of FABP4 mRNA]		 CTD PMID:9543393 PMID:12927809 PMID:15273253 PMID:16573735 PMID:17290005 More... NCBI chr 2:91,580,858...91,585,578
Ensembl chr 2:91,580,885...91,585,578 		JBrowse link
G Fam13a family with sequence similarity 13, member A increases expression ISO Pioglitazone results in increased expression of FAM13A mRNA CTD PMID:30031879 NCBI chr 4:88,056,521...88,155,782
Ensembl chr 4:88,058,403...88,155,860 		JBrowse link
G Fam171b family with sequence similarity 171, member B multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of FAM171B mRNA CTD PMID:27935865 NCBI chr 3:68,930,755...68,986,113
Ensembl chr 3:68,930,822...68,986,127 		JBrowse link
G Fam184b family with sequence similarity 184, member B multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of FAM184B mRNA CTD PMID:27935865 NCBI chr14:65,475,489...65,591,388
Ensembl chr14:65,475,489...65,591,388 		JBrowse link
G Fam210a family with sequence similarity 210, member A multiple interactions ISO [pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of FAM210A mRNA CTD PMID:20847119 NCBI chr18:61,846,447...61,886,123
Ensembl chr18:61,852,907...61,886,171 		JBrowse link
G Fam240b family with sequence similarity 240 member B multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with Pioglitazone] results in decreased expression of FAM240B mRNA CTD PMID:27935865 NCBI chr17:657,248...663,209
Ensembl chr17:657,303...663,206 		JBrowse link
G Fam47e family with sequence similarity 47, member E multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of FAM47E mRNA CTD PMID:27935865 NCBI chr14:15,485,537...15,521,599
Ensembl chr14:15,485,127...15,521,775 		JBrowse link
G Fat4 FAT atypical cadherin 4 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of FAT4 mRNA CTD PMID:27935865 NCBI chr 2:121,928,188...122,056,711
Ensembl chr 2:121,927,942...122,056,707 		JBrowse link
G Fbln1 fibulin 1 increases expression ISO Pioglitazone results in increased expression of FBLN1 mRNA CTD PMID:30031879 NCBI chr 7:116,310,582...116,390,075
Ensembl chr 7:116,310,582...116,390,075 		JBrowse link
G Fbln7 fibulin 7 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of FBLN7 mRNA CTD PMID:27935865 NCBI chr 3:116,111,581...116,145,839
Ensembl chr 3:116,111,677...116,147,983 		JBrowse link
G Fbxl16 F-box and leucine-rich repeat protein 16 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of FBXL16 mRNA CTD PMID:27935865 NCBI chr10:14,829,453...14,841,739
Ensembl chr10:14,829,449...14,840,986 		JBrowse link
G Fbxo40 F-box protein 40 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of FBXO40 mRNA CTD PMID:27935865 NCBI chr11:63,794,452...63,812,697
Ensembl chr11:63,794,624...63,812,697 		JBrowse link
G Fbxo43 F-box protein 43 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of FBXO43 mRNA CTD PMID:27935865 NCBI chr 7:67,333,161...67,346,751
Ensembl chr 7:67,333,162...67,346,751 		JBrowse link
G Fcmr Fc mu receptor increases expression ISO Pioglitazone results in increased expression of FCMR mRNA CTD PMID:30031879 NCBI chr13:42,337,363...42,351,706
Ensembl chr13:42,337,414...42,351,653 		JBrowse link
G Fgf21 fibroblast growth factor 21 increases expression ISO pioglitazone results in increased expression of FGF21 mRNA CTD PMID:21720023 NCBI chr 1:96,083,495...96,084,738
Ensembl chr 1:96,083,441...96,090,454 		JBrowse link
G Fgf7 fibroblast growth factor 7 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of FGF7 mRNA CTD PMID:27935865 NCBI chr 3:113,280,448...113,333,279
Ensembl chr 3:113,281,283...113,332,929 		JBrowse link
G Fgl1 fibrinogen-like 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of FGL1 mRNA CTD PMID:27935865 NCBI chr16:51,120,652...51,150,907
Ensembl chr16:51,120,694...51,151,093 		JBrowse link
G Fhl1 four and a half LIM domains 1 increases expression ISO Pioglitazone results in increased expression of FHL1 mRNA CTD PMID:30031879 NCBI chr  X:134,555,399...134,614,930
Ensembl chr  X:134,555,479...134,614,928 		JBrowse link
G Filip1 filamin A interacting protein 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of FILIP1 mRNA CTD PMID:27935865 NCBI chr 8:80,761,283...80,956,556
Ensembl chr 8:80,764,604...80,922,549 		JBrowse link
G Fjx1 four-jointed box kinase 1 multiple interactions ISO [pioglitazone co-treated with tert-Butylhydroperoxide] results in decreased expression of FJX1 mRNA CTD PMID:20847119 NCBI chr 3:88,774,220...88,776,321
Ensembl chr 3:88,774,220...88,776,321 		JBrowse link
G Fkbp1a FKBP prolyl isomerase 1A increases expression ISO Pioglitazone results in increased expression of FKBP1A mRNA CTD PMID:32589349 NCBI chr 3:140,040,359...140,060,107
Ensembl chr 3:140,040,278...140,060,743 		JBrowse link
G Fkbp8 FKBP prolyl isomerase 8 increases expression ISO Pioglitazone results in increased expression of FKBP8 mRNA CTD PMID:32589349 NCBI chr16:18,895,608...18,902,648
Ensembl chr16:18,893,576...18,902,612 		JBrowse link
G Flnc filamin C multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of FLNC mRNA CTD PMID:27935865 NCBI chr 4:58,034,088...58,061,882
Ensembl chr 4:58,034,189...58,061,844 		JBrowse link
G Fndc5 fibronectin type III domain containing 5 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of FNDC5 mRNA CTD PMID:27935865 NCBI chr 5:141,481,593...141,491,257
Ensembl chr 5:141,481,590...141,490,731 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression EXP pioglitazone results in increased expression of FOS mRNA CTD PMID:11687581 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of FOSB mRNA CTD PMID:27935865 NCBI chr 1:78,954,312...78,961,492
Ensembl chr 1:78,954,115...78,961,465 		JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of FOSL1 mRNA CTD PMID:27935865 NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930 		JBrowse link
G Foxn4 forkhead box N4 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of FOXN4 mRNA CTD PMID:27935865 NCBI chr12:42,336,706...42,359,932
Ensembl chr12:42,340,323...42,359,921 		JBrowse link
G Fpr1 formyl peptide receptor 1 decreases expression ISO Pioglitazone results in decreased expression of FPR1 mRNA CTD PMID:30031879 NCBI chr 1:58,745,019...58,756,776
Ensembl chr 1:58,747,246...58,756,559 		JBrowse link
G Frzb frizzled-related protein multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of FRZB mRNA CTD PMID:27935865 NCBI chr 3:65,332,274...65,365,208
Ensembl chr 3:65,332,277...65,365,208 		JBrowse link
G Fscn1 fascin actin-bundling protein 1 decreases expression ISO Pioglitazone results in decreased expression of FSCN1 mRNA CTD PMID:30031879 NCBI chr12:11,597,042...11,610,183
Ensembl chr12:11,597,048...11,610,211 		JBrowse link
G Fsd2 fibronectin type III and SPRY domain containing 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of FSD2 mRNA CTD PMID:27935865 NCBI chr 1:135,484,002...135,522,517
Ensembl chr 1:135,489,266...135,522,472 		JBrowse link
G Fxyd1 FXYD domain-containing ion transport regulator 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of FXYD1 mRNA CTD PMID:27935865 NCBI chr 1:86,287,163...86,291,478
Ensembl chr 1:86,287,165...86,291,278 		JBrowse link
G Gabra3 gamma-aminobutyric acid type A receptor subunit alpha 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of GABRA3 mRNA CTD PMID:27935865 NCBI chr  X:150,244,745...150,501,566
Ensembl chr  X:150,261,607...150,501,559 		JBrowse link
G Gabra4 gamma-aminobutyric acid type A receptor subunit alpha 4 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of GABRA4 mRNA CTD PMID:27935865 NCBI chr14:36,590,782...36,667,724
Ensembl chr14:36,590,782...36,665,844 		JBrowse link
G Galnt16 polypeptide N-acetylgalactosaminyltransferase 16 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of GALNT16 mRNA CTD PMID:27935865 NCBI chr 6:100,168,943...100,250,718
Ensembl chr 6:100,170,306...100,250,705 		JBrowse link
G Galnt17 polypeptide N-acetylgalactosaminyltransferase 17 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with Pioglitazone] results in decreased expression of GALNT17 mRNA CTD PMID:27935865 NCBI chr12:25,323,839...25,780,036
Ensembl chr12:25,322,701...25,781,290 		JBrowse link
G Galnt9 polypeptide N-acetylgalactosaminyltransferase 9 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of GALNT9 mRNA CTD PMID:27935865 NCBI chr12:46,050,395...46,128,626
Ensembl chr12:46,050,413...46,128,578 		JBrowse link
G Gdf15 growth differentiation factor 15 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of GDF15 mRNA CTD PMID:27935865 NCBI chr16:18,805,312...18,807,893
Ensembl chr16:18,805,239...18,808,055 		JBrowse link
G Gem GTP binding protein overexpressed in skeletal muscle multiple interactions ISO [pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of GEM mRNA CTD PMID:20847119 NCBI chr 5:25,214,309...25,225,222
Ensembl chr 5:25,214,309...25,225,222 		JBrowse link
G Gfra1 GDNF family receptor alpha 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of GFRA1 mRNA CTD PMID:27935865 NCBI chr 1:257,315,682...257,552,004
Ensembl chr 1:257,321,742...257,551,473 		JBrowse link
G Gh1 growth hormone 1 increases expression ISO Pioglitazone results in increased expression of GH1 mRNA CTD PMID:30031879 NCBI chr10:91,228,102...91,230,079
Ensembl chr10:91,228,103...91,230,078 		JBrowse link
G Gimap4 GTPase, IMAP family member 4 decreases expression ISO Pioglitazone results in decreased expression of GIMAP4 mRNA CTD PMID:30031879 NCBI chr 4:77,636,401...77,643,315
Ensembl chr 4:77,636,401...77,643,306 		JBrowse link
G Gldn gliomedin multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decre