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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:bexarotene
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Accession:CHEBI:50859 term browser browse the term
Definition:A retinoid that has formula C24H28O2.
Synonyms:exact_synonym: 4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)vinyl]benzoic acid
 related_synonym: Formula=C24H28O2;   InChI=1S/C24H28O2/c1-15-13-20-21(24(5,6)12-11-23(20,3)4)14-19(15)16(2)17-7-9-18(10-8-17)22(25)26/h7-10,13-14H,2,11-12H2,1,3-6H3,(H,25,26);   InChIKey=NAVMQTYZDKMPEU-UHFFFAOYSA-N;   SMILES=Cc1cc2c(cc1C(=C)c1ccc(cc1)C(O)=O)C(C)(C)CCC2(C)C;   bexaroteno;   bexarotenum;   p-(1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthyl)vinyl)benzoic acid
 xref: CAS:153559-49-0;   DrugBank:DB00307;   Drug_Central:361;   KEGG:D03106
 xref_mesh: MESH:C095105
 xref: Patent:US5466861;   Patent:WO9321146;   Wikipedia:Bexarotene


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bexarotene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A1bg alpha-1-B glycoprotein multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in decreased expression of A1BG mRNA CTD PMID:17630414 NCBI chr 7:102,294,805...102,298,522
Ensembl chr 7:102,294,797...102,298,522
JBrowse link
G Abca1 ATP binding cassette subfamily A member 1 increases expression
increases expression
multiple interactions
ISO bexarotene results in increased expression of ABCA1; bexarotene results in increased expression of ABCA1 mRNA
bexarotene increases expression of abca1 protein in mouse hippocampus
bexarotene increases expression of Abca1 protein in mouse cerebral cortex
diazepinylbenzoic acid inhibits the reaction [bexarotene results in increased expression of ABCA1 mRNA]
[bexarotene co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 protein
CTD PMID:21622945, PMID:25932594, PMID:25217640, PMID:26688581 RGD:21408550, RGD:11056803 NCBI chr 5:69,857,717...69,983,042
Ensembl chr 5:69,857,771...69,983,015
JBrowse link
G Abcb11 ATP binding cassette subfamily B member 11 increases expression EXP bexarotene results in increased expression of ABCB11 mRNA CTD PMID:16648578 NCBI chr 3:55,480,024...55,587,946
Ensembl chr 3:55,480,024...55,587,946
JBrowse link
G Abcd3 ATP binding cassette subfamily D member 3 increases expression EXP bexarotene results in increased expression of ABCD3 mRNA CTD PMID:16648578, PMID:23292798 NCBI chr 2:225,335,708...225,389,120
Ensembl chr 2:225,335,718...225,389,120
JBrowse link
G Acaa1a acetyl-CoA acyltransferase 1A increases expression
multiple interactions
EXP bexarotene results in increased expression of ACAA1 mRNA; bexarotene results in increased expression of ACAA1A mRNA
[Tamoxifen co-treated with bexarotene] results in increased expression of ACAA1 mRNA
CTD PMID:16648578, PMID:17630414 NCBI chr 8:128,027,880...128,036,471
Ensembl chr 8:128,027,958...128,036,236
JBrowse link
G Acaca acetyl-CoA carboxylase alpha increases expression EXP bexarotene results in increased expression of ACACA mRNA CTD PMID:23292798 NCBI chr10:71,519,392...71,719,910
Ensembl chr10:71,536,533...71,719,910
JBrowse link
G Acadm acyl-CoA dehydrogenase medium chain increases expression EXP bexarotene results in increased expression of ACADM mRNA CTD PMID:23292798 NCBI chr 2:260,124,418...260,148,589
Ensembl chr 2:260,124,418...260,148,589
JBrowse link
G Acat1 acetyl-CoA acetyltransferase 1 increases expression
multiple interactions
EXP bexarotene results in increased expression of ACAT1 mRNA
[Tamoxifen co-treated with bexarotene] results in increased expression of ACAT1 mRNA
CTD PMID:16648578, PMID:17630414 NCBI chr 8:58,166,990...58,195,884
Ensembl chr 8:58,166,990...58,195,884
JBrowse link
G Ache acetylcholinesterase decreases expression EXP bexarotene results in decreased expression of ACHE mRNA CTD PMID:16648578 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
JBrowse link
G Acot1 acyl-CoA thioesterase 1 increases expression
multiple interactions
EXP Bexarotene results in increased expression of ACOT1 mRNA
[Tamoxifen co-treated with Bexarotene] results in increased expression of ACOT1 mRNA
CTD PMID:16648578, PMID:17630414 NCBI chr 6:107,485,088...107,493,082
Ensembl chr 6:107,485,249...107,493,798
JBrowse link
G Acot2 acyl-CoA thioesterase 2 increases expression EXP bexarotene results in increased expression of ACOT2 mRNA CTD PMID:16648578 NCBI chr 6:107,460,596...107,468,324
Ensembl chr 6:107,460,668...107,467,487
JBrowse link
G Acox1 acyl-CoA oxidase 1 increases expression EXP bexarotene results in increased expression of ACOX1 mRNA CTD PMID:16648578, PMID:23292798 NCBI chr10:104,724,534...104,748,003
Ensembl chr10:104,722,958...104,748,050
JBrowse link
G Acsl1 acyl-CoA synthetase long-chain family member 1 increases expression EXP bexarotene results in increased expression of ACSL1 mRNA CTD PMID:23292798 NCBI chr16:48,937,456...49,003,898
Ensembl chr16:48,937,456...49,003,246
JBrowse link
G Acsl5 acyl-CoA synthetase long-chain family member 5 increases expression EXP bexarotene results in increased expression of ACSL5 mRNA CTD PMID:23292798 NCBI chr 1:276,240,703...276,290,012
Ensembl chr 1:276,240,703...276,290,008
JBrowse link
G Acsm3 acyl-CoA synthetase medium-chain family member 3 multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in increased expression of SAH mRNA CTD PMID:17630414 NCBI chr 1:189,514,504...189,541,233
Ensembl chr 1:189,514,553...189,541,224
JBrowse link
G Acta2 actin alpha 2, smooth muscle increases expression EXP bexarotene results in increased expression of ACTA2 mRNA CTD PMID:16648578 NCBI chr 1:252,537,614...252,550,394
Ensembl chr 1:252,537,615...252,550,394
JBrowse link
G Actc1 actin, alpha, cardiac muscle 1 increases expression EXP bexarotene results in increased expression of ACTC1 mRNA CTD PMID:16648578 NCBI chr 3:105,507,403...105,512,939
Ensembl chr 3:105,507,403...105,512,939
JBrowse link
G Actg1 actin, gamma 1 increases expression EXP bexarotene results in increased expression of ACTG1 mRNA CTD PMID:16648578 NCBI chr10:109,518,429...109,521,288
Ensembl chr 3:75,643,054...75,644,954
Ensembl chr10:75,643,054...75,644,954
JBrowse link
G Acvr2b activin A receptor type 2B increases expression EXP bexarotene results in increased expression of ACVR2B mRNA CTD PMID:16648578 NCBI chr 8:128,087,308...128,126,776
Ensembl chr 8:128,087,345...128,118,746
JBrowse link
G Adcy6 adenylate cyclase 6 decreases expression EXP bexarotene results in decreased expression of ADCY6 mRNA CTD PMID:16648578 NCBI chr 7:140,270,678...140,291,722
Ensembl chr 7:140,270,692...140,291,620
JBrowse link
G Add3 adducin 3 increases expression ISO bexarotene results in increased expression of ADD3 mRNA CTD PMID:17178900 NCBI chr 1:273,854,195...273,961,982
Ensembl chr 1:273,854,248...273,961,982
JBrowse link
G Adh4 alcohol dehydrogenase 4 (class II), pi polypeptide increases expression EXP bexarotene results in increased expression of ADH4 mRNA CTD PMID:17630414 NCBI chr 2:243,702,035...243,720,063
Ensembl chr 2:243,700,784...243,740,899
JBrowse link
G Adig adipogenin multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in increased expression of ADIG mRNA CTD PMID:17630414 NCBI chr 3:153,946,828...153,952,269
Ensembl chr 3:153,949,215...153,952,108
JBrowse link
G Adra1b adrenoceptor alpha 1B decreases expression EXP bexarotene results in decreased expression of ADRA1B mRNA CTD PMID:16648578 NCBI chr10:29,392,762...29,450,644
Ensembl chr10:29,392,762...29,450,644
JBrowse link
G Adrb2 adrenoceptor beta 2 decreases expression ISO bexarotene results in decreased expression of ADRB2 mRNA CTD PMID:17178900 NCBI chr18:57,513,792...57,515,834
Ensembl chr18:57,513,793...57,515,834
JBrowse link
G Agxt alanine--glyoxylate and serine--pyruvate aminotransferase increases expression EXP bexarotene results in increased expression of AGXT mRNA CTD PMID:16648578 NCBI chr 9:100,281,339...100,291,292
Ensembl chr 9:100,281,339...100,291,291
JBrowse link
G Ahsg alpha-2-HS-glycoprotein decreases expression EXP bexarotene results in decreased expression of AHSG mRNA CTD PMID:16648578 NCBI chr11:81,711,269...81,717,594 JBrowse link
G Akap12 A-kinase anchoring protein 12 increases expression EXP bexarotene results in increased expression of AKAP12 mRNA CTD PMID:16648578 NCBI chr 1:40,816,130...40,906,582
Ensembl chr 1:40,816,107...40,906,581
JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 increases expression ISO bexarotene results in increased expression of AKR1C3 mRNA CTD PMID:17178900 NCBI chr17:69,761,126...69,778,021
Ensembl chr17:69,761,118...69,778,021
JBrowse link
G Aldh3a2 aldehyde dehydrogenase 3 family, member A2 decreases expression EXP bexarotene results in decreased expression of ALDH3A2 mRNA CTD PMID:16648578 NCBI chr10:47,525,486...47,546,535
Ensembl chr10:47,525,493...47,546,345
JBrowse link
G Aldoa aldolase, fructose-bisphosphate A increases expression EXP Bexarotene results in increased expression of ALDOA mRNA CTD PMID:16648578 NCBI chr 1:198,228,387...198,233,988
Ensembl chr 1:198,228,387...198,233,588
JBrowse link
G Aldob aldolase, fructose-bisphosphate B decreases expression EXP bexarotene results in decreased expression of ALDOB mRNA CTD PMID:16648578 NCBI chr 5:64,805,772...64,818,813
Ensembl chr 5:64,805,773...64,818,824
JBrowse link
G Aldoc aldolase, fructose-bisphosphate C increases expression EXP bexarotene results in increased expression of ALDOC mRNA CTD PMID:16648578 NCBI chr10:65,586,504...65,590,093
Ensembl chr10:65,586,504...65,590,126
JBrowse link
G Alpl alkaline phosphatase, biomineralization associated increases expression EXP bexarotene results in increased expression of ALPL mRNA CTD PMID:16648578 NCBI chr 5:156,086,496...156,141,513
Ensembl chr 5:156,086,497...156,141,537
JBrowse link
G Amotl2 angiomotin like 2 decreases expression ISO bexarotene results in decreased expression of AMOTL2 mRNA CTD PMID:17178900 NCBI chr 8:111,210,261...111,226,217
Ensembl chr 8:111,209,908...111,226,226
JBrowse link
G Angptl4 angiopoietin-like 4 increases expression ISO bexarotene results in increased expression of ANGPTL4 mRNA CTD PMID:21622945 NCBI chr 7:18,627,814...18,634,043
Ensembl chr 7:18,627,808...18,634,079
JBrowse link
G Ank3 ankyrin 3 decreases expression EXP bexarotene results in decreased expression of ANK3 mRNA CTD PMID:16648578 NCBI chr20:19,948,767...20,480,628
Ensembl chr20:20,105,047...20,480,623
JBrowse link
G Anxa3 annexin A3 multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in decreased expression of ANXA3 mRNA CTD PMID:17630414 NCBI chr14:14,371,921...14,426,503
Ensembl chr14:14,364,008...14,426,437
JBrowse link
G Aplp2 amyloid beta precursor like protein 2 increases expression EXP bexarotene results in increased expression of APLP2 mRNA CTD PMID:16648578 NCBI chr 8:32,298,526...32,328,821
Ensembl chr 8:32,298,532...32,328,839
JBrowse link
G Apoa2 apolipoprotein A2 multiple interactions
increases expression
decreases expression
ISO
EXP
RXRA promotes the reaction [bexarotene results in increased expression of APOA2 mRNA]
bexarotene results in decreased expression of APOA2 mRNA
CTD PMID:8668150, PMID:16648578 NCBI chr13:89,596,872...89,598,805
Ensembl chr13:89,597,138...89,598,802
JBrowse link
G Apob apolipoprotein B decreases expression EXP bexarotene results in decreased expression of APOB mRNA CTD PMID:16648578 NCBI chr 6:33,176,826...33,216,381
Ensembl chr 6:33,176,778...33,224,997
JBrowse link
G Apoc1 apolipoprotein C1 decreases expression EXP bexarotene results in decreased expression of APOC1 mRNA CTD PMID:16648578 NCBI chr 1:80,606,638...80,609,921
Ensembl chr 1:80,606,638...80,609,921
JBrowse link
G Apoc3 apolipoprotein C3 decreases expression EXP bexarotene results in decreased expression of APOC3 mRNA CTD PMID:16648578 NCBI chr 8:50,529,318...50,531,498
Ensembl chr 8:50,529,318...50,531,498
JBrowse link
G Apod apolipoprotein D increases expression ISO bexarotene results in increased expression of APOD mRNA CTD PMID:17849452 NCBI chr11:72,705,204...72,726,263
Ensembl chr11:72,705,129...72,726,301
JBrowse link
G App amyloid beta precursor protein increases expression EXP bexarotene results in increased expression of APP mRNA CTD PMID:16648578 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858
JBrowse link
G Aqp7 aquaporin 7 multiple interactions
decreases expression
EXP [bexarotene co-treated with Tamoxifen] results in increased expression of AQP7 mRNA
bexarotene results in decreased expression of AQP7 mRNA
CTD PMID:16648578, PMID:17630414 NCBI chr 5:57,358,297...57,372,332
Ensembl chr 5:57,358,327...57,372,239
JBrowse link
G Ar androgen receptor multiple interactions
increases expression
ISO
EXP
bexarotene binds to and results in decreased activity of AR protein
bexarotene results in increased expression of AR mRNA
CTD PMID:16648578, PMID:25752796 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Arf1 ADP-ribosylation factor 1 increases expression EXP bexarotene results in increased expression of ARF1 mRNA CTD PMID:16648578 NCBI chr10:45,562,700...45,579,214
Ensembl chr10:45,563,547...45,579,029
JBrowse link
G Arg1 arginase 1 decreases expression EXP bexarotene results in decreased expression of ARG1 mRNA CTD PMID:16648578 NCBI chr 1:21,525,421...21,537,872
Ensembl chr 1:21,525,421...21,537,863
JBrowse link
G Arl6ip5 ADP-ribosylation factor like GTPase 6 interacting protein 5 increases expression ISO bexarotene results in increased expression of ARL6IP5 mRNA CTD PMID:17178900 NCBI chr 4:129,574,363...129,598,240
Ensembl chr 4:129,574,264...129,598,915
JBrowse link
G Arpc1b actin related protein 2/3 complex, subunit 1B increases expression EXP bexarotene results in increased expression of ARPC1B mRNA CTD PMID:16648578 NCBI chr12:11,252,300...11,265,849
Ensembl chr12:11,252,296...11,265,865
JBrowse link
G Ascl1 achaete-scute family bHLH transcription factor 1 multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in decreased expression of ASCL1 mRNA CTD PMID:17630414 NCBI chr 7:28,038,662...28,040,504
Ensembl chr 7:28,038,662...28,040,510
JBrowse link
G Asgr1 asialoglycoprotein receptor 1 increases expression EXP bexarotene results in increased expression of ASGR1 mRNA CTD PMID:16648578 NCBI chr10:56,662,188...56,666,086
Ensembl chr10:56,662,242...56,666,086
JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) decreases expression ISO bexarotene results in decreased expression of ASNS mRNA CTD PMID:17178900 NCBI chr 4:33,742,876...33,761,106
Ensembl chr 4:33,743,364...33,761,163
JBrowse link
G Atm ATM serine/threonine kinase increases activity ISO bexarotene results in increased activity of ATM protein CTD PMID:19067706 NCBI chr 8:58,015,938...58,119,973
Ensembl chr 8:58,015,940...58,120,045
JBrowse link
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 increases expression EXP bexarotene results in increased expression of ATP1A1 mRNA CTD PMID:16648578 NCBI chr 2:204,003,742...204,032,023
Ensembl chr 2:204,003,742...204,032,023
JBrowse link
G Atp1b1 ATPase Na+/K+ transporting subunit beta 1 decreases expression EXP bexarotene results in decreased expression of ATP1B1 mRNA CTD PMID:16648578 NCBI chr13:82,737,161...82,757,681
Ensembl chr13:82,737,159...82,758,004
JBrowse link
G Atp4a ATPase H+/K+ transporting subunit alpha increases expression EXP bexarotene results in increased expression of ATP4A mRNA CTD PMID:16648578 NCBI chr 1:89,162,700...89,175,504
Ensembl chr 1:89,162,639...89,175,811
JBrowse link
G Atp5f1d ATP synthase F1 subunit delta increases expression EXP bexarotene results in increased expression of ATP5F1D mRNA CTD PMID:16648578 NCBI chr 7:12,426,807...12,432,120
Ensembl chr 7:12,426,809...12,432,130
JBrowse link
G Atp6v0c ATPase H+ transporting V0 subunit C increases expression EXP bexarotene results in increased expression of ATP6V0C mRNA CTD PMID:16648578 NCBI chr10:13,537,031...13,543,407
Ensembl chr10:13,537,033...13,542,077
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO bexarotene results in increased expression of and results in increased activity of BAX protein CTD PMID:19067706 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bbs2 Bardet-Biedl syndrome 2 multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in increased expression of BBS2 mRNA CTD PMID:17630414 NCBI chr19:11,385,921...11,421,523
Ensembl chr19:11,386,024...11,421,498
JBrowse link
G Bglap bone gamma-carboxyglutamate protein multiple interactions ISO bexarotene inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA] CTD PMID:25932594 NCBI chr 2:187,741,770...187,748,445
Ensembl chr 2:187,741,770...187,742,747
JBrowse link
G Bhlhe41 basic helix-loop-helix family, member e41 decreases expression EXP bexarotene results in decreased expression of BHLHE41 mRNA CTD PMID:16648578 NCBI chr 4:180,230,742...180,235,138
Ensembl chr 4:180,232,382...180,234,804
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases expression ISO bexarotene results in decreased expression of BIRC5 mRNA
bexarotene results in decreased expression of BIRC5 protein
CTD PMID:17849452, PMID:19067706 NCBI chr10:106,856,097...106,864,419
Ensembl chr10:106,856,097...106,864,413
JBrowse link
G Bmp2 bone morphogenetic protein 2 multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in decreased expression of BMP2 mRNA CTD PMID:17630414 NCBI chr 3:126,335,963...126,346,771
Ensembl chr 3:126,335,863...126,346,318
JBrowse link
G Bnip2 BCL2 interacting protein 2 decreases expression ISO bexarotene results in decreased expression of BNIP2 mRNA CTD PMID:17178900 NCBI chr 8:76,400,333...76,426,307
Ensembl chr 8:76,400,341...76,426,503
JBrowse link
G Btg2 BTG anti-proliferation factor 2 decreases expression EXP bexarotene results in decreased expression of BTG2 mRNA CTD PMID:16648578 NCBI chr13:50,913,185...50,916,944
Ensembl chr13:50,913,180...50,916,982
JBrowse link
G C1qb complement C1q B chain multiple interactions
increases expression
EXP [bexarotene co-treated with Tamoxifen] results in decreased expression of C1QB mRNA
bexarotene results in increased expression of C1QB mRNA
CTD PMID:16648578, PMID:17630414 NCBI chr 5:155,246,444...155,251,995
Ensembl chr 5:155,246,447...155,252,003
JBrowse link
G C3 complement C3 decreases expression EXP bexarotene results in decreased expression of C3 mRNA CTD PMID:16648578 NCBI chr 9:9,721,137...9,747,084
Ensembl chr 9:9,721,105...9,747,167
JBrowse link
G C4bpa complement component 4 binding protein, alpha decreases expression EXP bexarotene results in decreased expression of C4BPA mRNA CTD PMID:16648578 NCBI chr13:47,342,090...47,377,580
Ensembl chr13:47,342,079...47,377,703
JBrowse link
G Cacna2d3 calcium voltage-gated channel auxiliary subunit alpha2delta 3 multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in increased expression of CACNA2D3 mRNA CTD PMID:17630414 NCBI chr16:4,871,348...5,795,825
Ensembl chr16:4,871,650...5,795,825
JBrowse link
G Calr calreticulin increases expression EXP bexarotene results in increased expression of CALR mRNA CTD PMID:16648578 NCBI chr19:25,956,771...25,961,666
Ensembl chr19:25,956,771...25,961,666
JBrowse link
G Camk2g calcium/calmodulin-dependent protein kinase II gamma increases expression EXP bexarotene results in increased expression of CAMK2G mRNA CTD PMID:16648578 NCBI chr15:3,936,721...3,995,740
Ensembl chr15:3,936,786...3,995,915
JBrowse link
G Canx calnexin increases expression EXP bexarotene results in increased expression of CANX mRNA CTD PMID:16648578 NCBI chr10:35,800,942...35,833,939
Ensembl chr10:35,800,942...35,833,861
JBrowse link
G Casp3 caspase 3 decreases expression ISO bexarotene results in decreased expression of CASP3 mRNA CTD PMID:17849452 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp6 caspase 6 decreases expression EXP bexarotene results in decreased expression of CASP6 mRNA CTD PMID:16648578 NCBI chr 2:235,341,326...235,353,715
Ensembl chr 2:235,341,365...235,353,967
Ensembl chr 2:235,341,365...235,353,967
JBrowse link
G Cbr1 carbonyl reductase 1 increases expression EXP bexarotene results in increased expression of CBR1 mRNA CTD PMID:16648578 NCBI chr11:33,813,041...33,815,418
Ensembl chr11:33,845,463...33,847,793
JBrowse link
G Ccl11 C-C motif chemokine ligand 11 decreases expression EXP bexarotene results in decreased expression of CCL11 mRNA CTD PMID:16648578 NCBI chr10:69,434,965...69,439,566
Ensembl chr10:69,434,941...69,439,575
JBrowse link
G Ccn1 cellular communication network factor 1 decreases expression ISO Bexarotene results in decreased expression of CCN1 mRNA CTD PMID:17178900 NCBI chr 2:251,529,354...251,532,312
Ensembl chr 2:251,529,354...251,532,312
JBrowse link
G Ccnb1 cyclin B1 decreases expression ISO bexarotene results in decreased expression of CCNB1 protein CTD PMID:19067706 NCBI chr 2:30,782,133...30,791,106
Ensembl chr 2:30,783,915...30,791,221
JBrowse link
G Ccnb2 cyclin B2 decreases expression ISO bexarotene results in decreased expression of CCNB2 mRNA CTD PMID:17849452 NCBI chr 8:76,847,972...76,861,165 JBrowse link
G Ccnd1 cyclin D1 increases expression
decreases expression
EXP
ISO
bexarotene results in increased expression of CCND1 mRNA
bexarotene results in decreased expression of CCND1 mRNA
CTD PMID:16648578, PMID:17178900 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Ccne1 cyclin E1 decreases expression ISO bexarotene results in decreased expression of CCNE1 mRNA CTD PMID:17849452 NCBI chr 1:94,485,830...94,495,112
Ensembl chr 1:94,485,832...94,494,980
JBrowse link
G Cd14 CD14 molecule increases expression EXP bexarotene results in increased expression of CD14 mRNA CTD PMID:16648578 NCBI chr18:29,560,341...29,562,290
Ensembl chr18:29,560,365...29,562,153
JBrowse link
G Cd36 CD36 molecule increases expression EXP bexarotene results in increased expression of CD36 mRNA CTD PMID:16648578, PMID:23292798 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749
JBrowse link
G Cd37 CD37 molecule increases expression EXP bexarotene results in increased expression of CD37 mRNA CTD PMID:16648578 NCBI chr 1:101,230,470...101,236,061
Ensembl chr 1:101,230,533...101,236,065
JBrowse link
G Cd48 Cd48 molecule multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in decreased expression of CD48 mRNA CTD PMID:17630414 NCBI chr13:90,116,601...90,140,371
Ensembl chr13:90,116,843...90,140,371
JBrowse link
G Cd5l Cd5 molecule-like multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in decreased expression of CD5L mRNA CTD PMID:17630414 NCBI chr 2:186,685,104...186,696,117
Ensembl chr 2:186,685,104...186,696,117
JBrowse link
G Cd68 Cd68 molecule multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in decreased expression of CD68 mRNA CTD PMID:17630414 NCBI chr10:56,268,726...56,270,605
Ensembl chr10:56,268,720...56,270,640
JBrowse link
G Cd74 CD74 molecule increases expression EXP bexarotene results in increased expression of CD74 mRNA CTD PMID:16648578 NCBI chr18:56,071,420...56,080,851
Ensembl chr18:56,071,478...56,080,849
JBrowse link
G Cdc37 cell division cycle 37, HSP90 cochaperone increases expression EXP bexarotene results in increased expression of CDC37 mRNA CTD PMID:16648578 NCBI chr 8:22,160,922...22,173,797
Ensembl chr 8:22,154,067...22,173,804
JBrowse link
G Cdk1 cyclin-dependent kinase 1 decreases expression ISO bexarotene results in decreased expression of CDK1 protein CTD PMID:19067706 NCBI chr20:20,576,341...20,591,510
Ensembl chr20:20,576,377...20,591,549
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO bexarotene results in increased expression of CDKN1A protein CTD PMID:19067706 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdo1 cysteine dioxygenase type 1 decreases expression EXP bexarotene results in decreased expression of CDO1 mRNA CTD PMID:16648578 NCBI chr18:40,702,027...40,716,901
Ensembl chr18:40,701,984...40,716,686
JBrowse link
G Cebpg CCAAT/enhancer binding protein gamma decreases expression ISO bexarotene results in decreased expression of CEBPG mRNA CTD PMID:17178900 NCBI chr 1:91,286,956...91,297,459
Ensembl chr 1:91,287,917...91,296,656
JBrowse link
G Ces2h carboxylesterase 2H increases expression
multiple interactions
EXP bexarotene results in increased expression of CES2 mRNA
[Tamoxifen co-treated with bexarotene] results in increased expression of CES2 mRNA
CTD PMID:16648578, PMID:17630414 NCBI chr19:37,052,555...37,067,176
Ensembl chr19:37,052,556...37,067,156
JBrowse link
G Cfd complement factor D multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in decreased expression of CFD mRNA CTD PMID:17630414 NCBI chr 7:12,634,216...12,635,939
Ensembl chr 7:12,634,216...12,635,943
JBrowse link
G Chrna2 cholinergic receptor nicotinic alpha 2 subunit increases expression EXP bexarotene results in increased expression of CHRNA2 mRNA CTD PMID:16648578, PMID:17630414 NCBI chr15:42,808,897...42,825,179
Ensembl chr15:42,808,897...42,825,179
JBrowse link
G Ciao1 cytosolic iron-sulfur assembly component 1 decreases expression EXP bexarotene results in decreased expression of CIAO1 mRNA CTD PMID:16648578 NCBI chr 3:119,671,778...119,677,324
Ensembl chr 3:119,671,779...119,678,092
JBrowse link
G Ckb creatine kinase B increases expression EXP bexarotene results in increased expression of CKB mRNA CTD PMID:16648578 NCBI chr 6:136,142,956...136,145,838
Ensembl chr 6:136,142,956...136,145,837
JBrowse link
G Cldn3 claudin 3 increases expression EXP bexarotene results in increased expression of CLDN3 mRNA CTD PMID:16648578 NCBI chr12:21,831,341...21,832,813
Ensembl chr12:21,831,342...21,832,813
JBrowse link
G Cldn7 claudin 7 increases expression EXP bexarotene results in increased expression of CLDN7 mRNA CTD PMID:16648578 NCBI chr10:56,576,326...56,578,632
Ensembl chr10:56,576,428...56,578,626
JBrowse link
G Col12a1 collagen type XII alpha 1 chain decreases expression EXP bexarotene results in decreased expression of COL12A1 mRNA CTD PMID:16648578 NCBI chr 8:87,042,820...87,150,701
Ensembl chr 8:87,040,799...87,158,368
JBrowse link
G Colq collagen like tail subunit of asymmetric acetylcholinesterase increases expression EXP bexarotene results in increased expression of COLQ mRNA CTD PMID:16648578 NCBI chr16:7,626,380...7,681,621
Ensembl chr16:7,627,603...7,681,576
JBrowse link
G Comt catechol-O-methyltransferase decreases expression
increases expression
EXP bexarotene results in decreased expression of COMT mRNA
bexarotene results in increased expression of COMT mRNA
CTD PMID:16648578 NCBI chr11:86,715,981...86,735,630
Ensembl chr11:86,715,981...86,735,622
JBrowse link
G Coro1b coronin 1B increases expression EXP bexarotene results in increased expression of CORO1B mRNA CTD PMID:16648578 NCBI chr 1:219,397,827...219,403,253
Ensembl chr 1:219,397,850...219,403,260
JBrowse link
G Cpa1 carboxypeptidase A1 multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in decreased expression of CPA1 mRNA CTD PMID:17630414 NCBI chr 4:57,952,982...57,959,109
Ensembl chr 4:57,952,982...57,959,109
JBrowse link
G Cps1 carbamoyl-phosphate synthase 1 decreases expression EXP bexarotene results in decreased expression of CPS1 mRNA CTD PMID:16648578 NCBI chr 9:74,113,437...74,236,274
Ensembl chr 9:74,124,016...74,236,274
JBrowse link
G Cpt1b carnitine palmitoyltransferase 1B multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in increased expression of CPT1B mRNA CTD PMID:17630414 NCBI chr 7:130,395,211...130,404,731
Ensembl chr 7:130,395,194...130,405,347
JBrowse link
G Cpt2 carnitine palmitoyltransferase 2 increases expression EXP bexarotene results in increased expression of CPT2 mRNA CTD PMID:16648578 NCBI chr 5:127,505,646...127,523,016
Ensembl chr 5:127,505,614...127,523,089
JBrowse link
G Crot carnitine O-octanoyltransferase increases expression EXP bexarotene results in increased expression of CROT mRNA CTD PMID:16648578 NCBI chr 4:22,079,837...22,116,265
Ensembl chr 4:22,081,604...22,116,265
JBrowse link
G Csf1r colony stimulating factor 1 receptor multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in decreased expression of CSF1R mRNA CTD PMID:17630414 NCBI chr18:56,414,493...56,458,300
Ensembl chr18:56,414,488...56,458,300
JBrowse link
G Cspg5 chondroitin sulfate proteoglycan 5 increases expression EXP bexarotene results in increased expression of CSPG5 mRNA CTD PMID:16648578 NCBI chr 8:118,333,695...118,348,040
Ensembl chr 8:118,333,706...118,347,582
JBrowse link
G Csrp2 cysteine and glycine-rich protein 2 decreases expression EXP bexarotene results in decreased expression of CSRP2 mRNA CTD PMID:16648578 NCBI chr 7:53,630,675...53,649,309
Ensembl chr 7:53,630,621...53,649,310
JBrowse link
G Cth cystathionine gamma-lyase decreases expression ISO bexarotene results in decreased expression of CTH mRNA CTD PMID:17178900 NCBI chr 2:264,266,959...264,293,040
Ensembl chr 2:264,266,984...264,293,046
JBrowse link
G Ctrc chymotrypsin C increases expression EXP bexarotene results in increased expression of CTRC mRNA CTD PMID:16648578 NCBI chr 5:160,394,677...160,403,373
Ensembl chr 5:160,394,580...160,405,050
JBrowse link
G Ctsh cathepsin H increases expression ISO bexarotene results in increased expression of CTSH mRNA CTD PMID:17178900 NCBI chr 8:97,439,155...97,458,293
Ensembl chr 8:97,439,161...97,458,287
JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in decreased expression of CXCL1 mRNA CTD PMID:17630414 NCBI chr14:18,743,678...18,745,457
Ensembl chr14:18,743,685...18,745,457
JBrowse link
G Cxcl14 C-X-C motif chemokine ligand 14 decreases expression EXP bexarotene results in decreased expression of CXCL14 mRNA CTD PMID:16648578 NCBI chr17:9,109,731...9,117,754
Ensembl chr17:9,109,731...9,117,750
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 decreases expression EXP bexarotene results in decreased expression of CXCL3 mRNA CTD PMID:16648578 NCBI chr14:18,820,168...18,839,659
Ensembl chr14:18,820,168...18,839,595
JBrowse link
G Cyb5a cytochrome b5 type A decreases expression EXP bexarotene results in decreased expression of CYB5A mRNA CTD PMID:16648578 NCBI chr18:81,694,818...81,726,821
Ensembl chr18:81,694,808...81,726,821
JBrowse link
G Cycs cytochrome c, somatic decreases expression ISO bexarotene results in decreased expression of CYCS mRNA CTD PMID:17178900 NCBI chr 4:80,331,226...80,333,326
Ensembl chr 4:80,331,227...80,333,326
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in increased expression of CYP17A1 mRNA CTD PMID:17630414 NCBI chr 1:266,422,127...266,429,947
Ensembl chr 1:266,422,132...266,428,239
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases expression EXP bexarotene results in decreased expression of CYP1A2 mRNA CTD PMID:16648578 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases expression EXP bexarotene results in increased expression of CYP1B1 mRNA CTD PMID:16648578 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 increases expression
multiple interactions
ISO
EXP
bexarotene results in increased expression of CYP26A1 mRNA
[bexarotene co-treated with Tamoxifen] results in increased expression of CYP26A1 mRNA
CTD PMID:17178900, PMID:17630414 NCBI chr 1:256,382,861...256,386,729
Ensembl chr 1:256,382,791...256,386,729
JBrowse link
G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 increases expression ISO bexarotene results in increased expression of CYP26B1 mRNA CTD PMID:17849452 NCBI chr 4:116,261,796...116,278,615
Ensembl chr 4:116,261,796...116,278,615
JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 increases expression EXP bexarotene results in increased expression of CYP27A1 mRNA CTD PMID:16648578 NCBI chr 9:81,968,285...81,998,213
Ensembl chr 9:81,968,332...81,998,169
JBrowse link
G Cyp2a1 cytochrome P450, family 2, subfamily a, polypeptide 1 multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in increased expression of CYP2A1 mRNA CTD PMID:17630414 NCBI chr 1:83,711,223...83,725,222
Ensembl chr 1:83,653,234...83,766,484
JBrowse link
G Cyp2a2 cytochrome P450, family 2, subfamily a, polypeptide 2 decreases expression EXP bexarotene results in decreased expression of CYP2A2 mRNA CTD PMID:16648578 NCBI chr 1:83,744,229...83,766,490
Ensembl chr 1:83,653,234...83,766,484
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 increases expression EXP bexarotene results in increased expression of CYP2B1 mRNA CTD PMID:23292798 NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783
JBrowse link
G Cyp2b15 cytochrome P450, family 2, subfamily b, polypeptide 15 increases expression EXP bexarotene results in increased expression of CYP2B15 mRNA CTD PMID:16648578 NCBI chr 1:251,325,923...251,338,404
Ensembl chr 1:251,325,923...251,338,358
JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 increases expression EXP bexarotene results in increased expression of CYP2B2 mRNA CTD PMID:16648578 NCBI chr 1:83,103,925...83,119,578
Ensembl chr 1:83,103,925...83,119,193
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases expression
multiple interactions
ISO Bexarotene results in increased expression of CYP2B6 mRNA
RXRA protein affects the reaction [Bexarotene results in increased expression of CYP2B6 mRNA]
CTD PMID:31312845 NCBI chr 1:83,163,103...83,236,615
Ensembl chr 1:83,163,079...83,236,615
JBrowse link
G Cyp2c12 cytochrome P450, family 2, subfamily c, polypeptide 12 decreases expression EXP bexarotene results in decreased expression of CYP2C12 mRNA CTD PMID:16648578 NCBI chr 1:258,709,726...258,766,873
Ensembl chr 1:258,709,721...258,766,881
JBrowse link
G Cyp2c7 cytochrome P450, family 2, subfamily c, polypeptide 7 decreases expression EXP bexarotene results in decreased expression of CYP2C7 mRNA CTD PMID:16648578 NCBI chr 1:147,422,999...148,119,979
Ensembl chr 1:148,053,687...148,119,857
JBrowse link
G Cyp2d3 cytochrome P450, family 2, subfamily d, polypeptide 3 increases expression EXP bexarotene results in increased expression of CYP2D3 mRNA CTD PMID:16648578 NCBI chr 7:123,634,400...123,638,757
Ensembl chr 7:123,625,590...123,638,765
JBrowse link
G Cyp2t1 cytochrome P450, family 2, subfamily t, polypeptide 1 decreases expression
multiple interactions
EXP bexarotene results in decreased expression of CYP2T1 mRNA
[Tamoxifen co-treated with bexarotene] results in decreased expression of CYP2T1 mRNA
CTD PMID:17630414 NCBI chr 1:83,965,370...83,969,466
Ensembl chr 1:83,965,608...83,969,559
JBrowse link
G Cyp3a18 cytochrome P450, family 3, subfamily a, polypeptide 18 decreases expression EXP bexarotene results in decreased expression of CYP3A18 mRNA CTD PMID:16648578 NCBI chr12:10,636,294...10,684,273
Ensembl chr12:10,636,275...10,684,278
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 decreases expression
increases expression
EXP Bexarotene results in decreased expression of CYP3A23-3A1 mRNA
Bexarotene results in increased expression of CYP3A23-3A1 mRNA
CTD PMID:16648578, PMID:23292798 NCBI chr12:11,053,888...11,082,742
Ensembl chr12:11,655,402...11,733,136
JBrowse link
G Cyp4a1 cytochrome P450, family 4, subfamily a, polypeptide 1 increases expression EXP bexarotene results in increased expression of CYP4A22 mRNA CTD PMID:16648578 NCBI chr 5:134,492,734...134,507,158
Ensembl chr 5:134,492,756...134,507,154
JBrowse link
G Cyp4f1 cytochrome P450, family 4, subfamily f, polypeptide 1 decreases expression EXP bexarotene results in decreased expression of CYP4F1 mRNA CTD PMID:16648578 NCBI chr 7:15,179,472...15,191,113
Ensembl chr 7:15,179,467...15,190,796
JBrowse link
G Cyp8b1 cytochrome P450 family 8 subfamily B member 1 multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in decreased expression of CYP8B1 mRNA CTD PMID:17630414 NCBI chr 8:130,548,418...130,550,388
Ensembl chr 8:130,548,418...130,550,388
JBrowse link
G Dab2 DAB adaptor protein 2 decreases expression EXP Bexarotene results in decreased expression of DAB2 mRNA CTD PMID:16648578 NCBI chr 2:55,747,353...55,768,848
Ensembl chr 2:55,747,318...55,768,270
JBrowse link
G Dact2 dishevelled-binding antagonist of beta-catenin 2 increases expression EXP bexarotene results in increased expression of DACT2 mRNA CTD PMID:17630414 NCBI chr 1:56,159,435...56,169,443
Ensembl chr 1:56,159,426...56,168,351
JBrowse link
G Dapk3 death-associated protein kinase 3 decreases expression EXP bexarotene results in decreased expression of DAPK3 mRNA CTD PMID:16648578 NCBI chr 7:11,392,436...11,400,855
Ensembl chr 7:11,392,437...11,400,805
JBrowse link
G Dbp D-box binding PAR bZIP transcription factor decreases expression EXP bexarotene results in decreased expression of DBP mRNA CTD PMID:16648578 NCBI chr 1:101,687,896...101,692,845
Ensembl chr 1:101,687,855...101,692,846
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 decreases expression EXP bexarotene results in decreased expression of DDIT3 mRNA CTD PMID:16648578 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 increases expression ISO bexarotene results in increased expression of DDIT4 mRNA CTD PMID:17178900 NCBI chr20:29,509,283...29,511,382
Ensembl chr20:29,509,289...29,511,382
JBrowse link
G Decr2 2,4-dienoyl-CoA reductase 2 increases expression EXP bexarotene results in increased expression of DECR2 mRNA CTD PMID:16648578 NCBI chr10:15,451,850...15,460,227
Ensembl chr10:15,431,638...15,465,413
JBrowse link
G Depp1 DEPP1, autophagy regulator increases expression ISO bexarotene results in increased expression of DEPP1 mRNA CTD PMID:17178900 NCBI chr 4:148,780,330...148,784,566
Ensembl chr 4:148,782,479...148,784,562
JBrowse link
G Dhcr7 7-dehydrocholesterol reductase increases expression EXP bexarotene results in increased expression of DHCR7 mRNA CTD PMID:16648578 NCBI chr 1:217,018,916...217,034,890
Ensembl chr 1:217,018,916...217,034,904
JBrowse link
G Dhrs3 dehydrogenase/reductase 3 increases expression ISO bexarotene results in increased expression of DHRS3 mRNA CTD PMID:17178900 NCBI chr 5:162,809,090...162,843,385
Ensembl chr 5:162,808,646...162,843,383
JBrowse link
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 increases expression ISO bexarotene results in increased expression of DKK1 mRNA CTD PMID:17178900 NCBI chr 1:248,952,896...248,956,579
Ensembl chr 1:248,895,738...248,898,607
JBrowse link
G Dlat dihydrolipoamide S-acetyltransferase increases expression EXP bexarotene results in increased expression of DLAT mRNA CTD PMID:16648578 NCBI chr 8:55,062,549...55,087,832
Ensembl chr 8:55,062,551...55,087,832
JBrowse link
G Dmp1 dentin matrix acidic phosphoprotein 1 multiple interactions ISO bexarotene inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of DMP1 mRNA] CTD PMID:25932594 NCBI chr14:6,889,851...6,923,961
Ensembl chr14:6,889,856...6,900,733
JBrowse link
G Dnaja1 DnaJ heat shock protein family (Hsp40) member A1 decreases expression EXP bexarotene results in decreased expression of DNAJA1 mRNA CTD PMID:16648578 NCBI chr 5:57,028,467...57,039,378
Ensembl chr 5:57,028,467...57,039,378
JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha decreases expression ISO bexarotene results in decreased expression of DNMT3A mRNA CTD PMID:17849452 NCBI chr 6:28,205,375...28,346,052
Ensembl chr 6:28,235,695...28,340,577
JBrowse link
G Dusp1 dual specificity phosphatase 1 decreases expression ISO
EXP
bexarotene results in decreased expression of DUSP1 mRNA CTD PMID:16648578, PMID:17178900 NCBI chr10:16,970,642...16,973,425
Ensembl chr10:16,970,626...16,973,418
JBrowse link
G Dusp5 dual specificity phosphatase 5 decreases expression ISO bexarotene results in decreased expression of DUSP5 mRNA CTD PMID:17178900 NCBI chr 1:274,245,184...274,258,595
Ensembl chr 1:274,245,184...274,258,595
JBrowse link
G Dync1i2 dynein cytoplasmic 1 intermediate chain 2 decreases expression EXP bexarotene results in decreased expression of DYNC1I2 mRNA CTD PMID:16648578 NCBI chr 3:57,817,677...57,868,854
Ensembl chr 3:57,817,693...57,868,854
JBrowse link
G Ech1 enoyl-CoA hydratase 1 increases expression EXP bexarotene results in increased expression of ECH1 mRNA CTD PMID:23292798 NCBI chr 1:87,009,798...87,015,996
Ensembl chr 1:87,009,730...87,016,005
JBrowse link
G Echdc1 ethylmalonyl-CoA decarboxylase 1 increases expression EXP bexarotene results in increased expression of ECHDC1 mRNA CTD PMID:23292798 NCBI chr 1:30,874,410...30,921,117
Ensembl chr 1:30,874,418...30,917,882
JBrowse link
G Eci1 enoyl-CoA delta isomerase 1 increases expression EXP bexarotene results in increased expression of ECI1 mRNA CTD PMID:16648578 NCBI chr10:13,797,573...13,810,918
Ensembl chr10:13,797,562...13,810,913
JBrowse link
G Ednrb endothelin receptor type B increases expression EXP bexarotene results in increased expression of EDNRB mRNA CTD PMID:16648578 NCBI chr15:88,004,775...88,036,354
Ensembl chr15:88,006,977...88,036,354
JBrowse link
G Egf epidermal growth factor increases expression EXP bexarotene results in increased expression of EGF mRNA CTD PMID:16648578 NCBI chr 2:68,820,616...68,895,537 JBrowse link
G Egr1 early growth response 1 multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in decreased expression of EGR1 mRNA CTD PMID:17630414 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
JBrowse link
G Egr3 early growth response 3 decreases expression ISO bexarotene results in decreased expression of EGR3 mRNA CTD PMID:17178900 NCBI chr15:51,756,683...51,762,080
Ensembl chr15:51,756,736...51,760,722
JBrowse link
G Ehhadh enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase multiple interactions
increases expression
EXP [Tamoxifen co-treated with bexarotene] results in increased expression of EHHADH mRNA
bexarotene results in increased expression of EHHADH mRNA
CTD PMID:16648578, PMID:17630414 NCBI chr11:82,945,104...82,978,364
Ensembl chr11:82,945,104...82,978,364
JBrowse link
G Eif1 eukaryotic translation initiation factor 1 decreases expression ISO bexarotene results in decreased expression of EIF1 mRNA CTD PMID:17178900 NCBI chr10:88,227,455...88,229,546
Ensembl chr10:88,227,360...88,229,765
JBrowse link
G Eif3c eukaryotic translation initiation factor 3, subunit C decreases expression EXP bexarotene results in decreased expression of EIF3C mRNA CTD PMID:17630414 NCBI chr 1:197,964,406...197,982,917
Ensembl chr 1:197,964,407...197,982,601
JBrowse link
G Elovl6 ELOVL fatty acid elongase 6 multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in increased expression of ELOVL6 mRNA CTD PMID:17630414 NCBI chr 2:234,187,490...234,296,124
Ensembl chr 2:234,189,105...234,296,145
Ensembl chr 2:234,189,105...234,296,145
JBrowse link
G Eno1 enolase 1 increases expression EXP bexarotene results in increased expression of ENO1 mRNA CTD PMID:16648578 NCBI chr 5:167,288,223...167,299,610
Ensembl chr 5:167,288,223...167,299,609
JBrowse link
G Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 decreases expression EXP bexarotene results in decreased expression of ENPP2 mRNA CTD PMID:16648578 NCBI chr 7:94,479,931...94,563,086
Ensembl chr 7:94,480,396...94,563,001
JBrowse link
G Epha2 Eph receptor A2 decreases expression ISO bexarotene results in decreased expression of EPHA2 mRNA CTD PMID:17178900 NCBI chr 5:159,845,773...159,874,203
Ensembl chr 5:159,845,774...159,874,206
JBrowse link
G Ephx1 epoxide hydrolase 1 increases expression EXP bexarotene results in increased expression of EPHX1 mRNA CTD PMID:23292798 NCBI chr13:99,271,390...99,300,580
Ensembl chr13:99,271,366...99,300,579
JBrowse link
G Ephx2 epoxide hydrolase 2 increases expression EXP bexarotene results in increased expression of EPHX2 mRNA CTD PMID:23292798 NCBI chr15:42,757,241...42,794,211
Ensembl chr15:42,757,235...42,794,279
JBrowse link
G Erp29 endoplasmic reticulum protein 29 increases expression EXP bexarotene results in increased expression of ERP29 mRNA CTD PMID:16648578 NCBI chr12:40,619,377...40,625,884
Ensembl chr12:40,619,377...40,625,883
JBrowse link
G Esr1 estrogen receptor 1 decreases expression ISO bexarotene results in decreased expression of ESR1 mRNA CTD PMID:17849452 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions ISO bexarotene binds to and results in decreased activity of ESR2 protein CTD PMID:25752796 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link
G F2 coagulation factor II decreases expression EXP bexarotene results in decreased expression of F2 mRNA CTD PMID:16648578 NCBI chr 3:80,529,468...80,542,993
Ensembl chr 3:80,529,428...80,543,031
JBrowse link
G Fabp1 fatty acid binding protein 1 decreases expression EXP bexarotene results in decreased expression of FABP1 mRNA CTD PMID:16648578 NCBI chr 4:99,063,181...99,066,957
Ensembl chr 4:99,063,181...99,066,954
JBrowse link
G Fabp2 fatty acid binding protein 2 decreases expression
multiple interactions
EXP bexarotene results in decreased expression of FABP2 mRNA
[Tamoxifen co-treated with bexarotene] results in decreased expression of FABP2 mRNA
CTD PMID:17630414 NCBI chr 2:227,080,912...227,083,654
Ensembl chr 2:227,080,924...227,083,501
JBrowse link
G Fabp3 fatty acid binding protein 3 multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in increased expression of FABP3 mRNA CTD PMID:17630414 NCBI chr 5:148,528,854...148,535,597
Ensembl chr 5:148,528,725...148,535,565
JBrowse link
G Fabp4 fatty acid binding protein 4 increases expression ISO bexarotene results in increased expression of FABP4 mRNA; bexarotene results in increased expression of FABP4 protein CTD PMID:21622945, PMID:25932594 NCBI chr 2:93,792,666...93,797,267
Ensembl chr 2:93,792,601...93,797,305
JBrowse link
G Fads2 fatty acid desaturase 2 increases expression
multiple interactions
EXP bexarotene results in increased expression of FADS2 mRNA
[Tamoxifen co-treated with bexarotene] results in increased expression of FADS2 mRNA
CTD PMID:17630414 NCBI chr 1:225,906,582...226,152,568
Ensembl chr 1:226,114,413...226,152,524
JBrowse link
G Fam13a family with sequence similarity 13, member A decreases expression EXP bexarotene results in decreased expression of FAM13A mRNA CTD PMID:17630414 NCBI chr 4:89,183,180...89,281,282
Ensembl chr 4:89,183,768...89,281,222
JBrowse link
G Fasn fatty acid synthase multiple interactions
increases expression
EXP
ISO
[Tamoxifen co-treated with bexarotene] results in increased expression of FASN mRNA
[Bexarotene co-treated with GW 3965] results in increased expression of FASN mRNA; [Bexarotene co-treated with paxilline] results in increased expression of FASN mRNA; [Bexarotene co-treated with TO-901317] results in increased expression of FASN mRNA
bexarotene results in increased expression of FASN mRNA
CTD PMID:16648578, PMID:17630414, PMID:32123961 NCBI chr10:109,987,735...110,005,901
Ensembl chr10:109,987,735...110,005,901
JBrowse link
G Fcgr2a Fc fragment of IgG receptor IIa multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in decreased expression of FCGR3 mRNA CTD PMID:17630414 NCBI chr13:91,146,878...91,163,691
Ensembl chr13:91,168,973...91,198,036
Ensembl chr13:91,168,973...91,198,036
JBrowse link
G Fcgr2b Fc fragment of IgG receptor IIb multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in decreased expression of FCGR2B mRNA CTD PMID:17630414 NCBI chr13:89,329,298...89,343,916
Ensembl chr13:89,327,794...89,433,815
JBrowse link
G Fcna ficolin A multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in decreased expression of FCNA mRNA CTD PMID:17630414 NCBI chr 3:2,850,006...2,853,230
Ensembl chr 3:2,849,984...2,853,272
JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 increases expression EXP bexarotene results in increased expression of FDFT1 mRNA CTD PMID:16648578 NCBI chr15:46,339,248...46,367,302
Ensembl chr15:46,339,249...46,367,302
JBrowse link
G Fga fibrinogen alpha chain decreases expression EXP bexarotene results in decreased expression of FGA mRNA CTD PMID:16648578 NCBI chr 2:181,997,562...182,013,726
Ensembl chr 2:182,006,242...182,013,763
JBrowse link
G Fgb fibrinogen beta chain decreases expression EXP bexarotene results in decreased expression of FGB mRNA CTD PMID:16648578 NCBI chr 2:182,028,044...182,035,026
Ensembl chr 2:182,027,115...182,038,178
JBrowse link
G Fgg fibrinogen gamma chain decreases expression EXP bexarotene results in decreased expression of FGG mRNA CTD PMID:16648578 NCBI chr 2:181,987,080...181,994,523
Ensembl chr 2:181,987,217...181,994,514
JBrowse link
G Fh fumarate hydratase decreases expression EXP bexarotene results in decreased expression of FH1 mRNA CTD PMID:16648578 NCBI chr13:93,651,486...93,677,371
Ensembl chr13:93,651,484...93,677,377
JBrowse link
G Fmo1 flavin containing dimethylaniline monoxygenase 1 decreases expression EXP bexarotene results in decreased expression of FMO1 mRNA CTD PMID:16648578 NCBI chr13:80,712,885...80,745,095
Ensembl chr13:80,712,882...80,745,347
JBrowse link
G Fn1 fibronectin 1 increases expression EXP bexarotene results in increased expression of FN1 mRNA CTD PMID:16648578 NCBI chr 9:78,900,111...78,969,018
Ensembl chr 9:78,900,103...78,969,078
JBrowse link
G Foxa1 forkhead box A1 increases expression EXP bexarotene results in increased expression of FOXA1 mRNA CTD PMID:16648578 NCBI chr 6:78,516,579...78,549,669
Ensembl chr 6:78,545,804...78,549,669
JBrowse link
G Foxa2 forkhead box A2 decreases expression EXP bexarotene results in decreased expression of FOXA2 mRNA CTD PMID:16648578 NCBI chr 3:142,383,084...142,387,493
Ensembl chr 3:142,383,278...142,387,481
JBrowse link
G Galr2 galanin receptor 2 increases expression EXP bexarotene results in increased expression of GALR2 mRNA CTD PMID:16648578 NCBI chr10:105,156,793...105,159,221
Ensembl chr10:105,156,632...105,237,611
JBrowse link
G Gars glycyl-tRNA synthetase decreases expression ISO Bexarotene results in decreased expression of GARS1 mRNA CTD PMID:17178900 NCBI chr 4:85,235,122...85,276,085
Ensembl chr 4:85,235,172...85,276,044
JBrowse link
G Gas6 growth arrest specific 6 decreases expression
multiple interactions
EXP bexarotene results in decreased expression of GAS6 mRNA
[bexarotene co-treated with Tamoxifen] results in decreased expression of GAS6 mRNA
CTD PMID:16648578, PMID:17630414 NCBI chr16:81,213,364...81,243,824
Ensembl chr16:81,213,364...81,243,757
JBrowse link
G Gas7 growth arrest specific 7 increases expression EXP bexarotene results in increased expression of GAS7 mRNA CTD PMID:16648578 NCBI chr10:54,010,723...54,240,805
Ensembl chr10:54,126,486...54,236,476
JBrowse link
G Gc GC, vitamin D binding protein decreases expression EXP bexarotene results in decreased expression of GC mRNA CTD PMID:16648578 NCBI chr14:20,267,023...20,302,577
Ensembl chr14:20,266,891...20,302,581
JBrowse link
G Gcgr glucagon receptor decreases expression EXP bexarotene results in decreased expression of GCGR mRNA CTD PMID:16648578 NCBI chr10:109,707,863...109,716,253
Ensembl chr10:109,707,962...109,716,128
JBrowse link
G Ghrh growth hormone releasing hormone increases expression EXP bexarotene results in increased expression of GHRH mRNA CTD PMID:16648578 NCBI chr 3:153,449,124...153,468,794
Ensembl chr 3:153,449,125...153,468,794
JBrowse link
G Glra3 glycine receptor, alpha 3 increases expression EXP bexarotene results in increased expression of GLRA3 mRNA CTD PMID:16648578 NCBI chr16:37,676,959...37,908,221
Ensembl chr16:37,676,962...38,063,821
JBrowse link
G Gosr1 golgi SNAP receptor complex member 1 increases expression EXP bexarotene results in increased expression of GOSR1 mRNA CTD PMID:16648578 NCBI chr10:63,405,526...63,442,257
Ensembl chr10:63,405,586...63,442,250
JBrowse link
G Gpd1 glycerol-3-phosphate dehydrogenase 1 increases expression EXP bexarotene results in increased expression of GPD1 mRNA CTD PMID:23292798 NCBI chr 7:141,368,928...141,377,931
Ensembl chr 7:141,370,491...141,377,928
JBrowse link
G Gpd2 glycerol-3-phosphate dehydrogenase 2 multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in increased expression of GPD2 mRNA CTD PMID:17630414 NCBI chr 3:43,223,892...43,359,069
Ensembl chr 3:43,255,567...43,359,074
JBrowse link
G Gpm6a glycoprotein m6a multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in increased expression of GPM6A mRNA CTD PMID:17630414 NCBI chr16:39,367,697...39,719,292
Ensembl chr16:39,367,692...39,719,187
JBrowse link
G Gpm6b glycoprotein m6b increases expression ISO bexarotene results in increased expression of GPM6B mRNA CTD PMID:17178900 NCBI chr  X:29,604,607...29,751,174
Ensembl chr  X:29,607,075...29,648,403
JBrowse link
G Gpx4 glutathione peroxidase 4 increases expression EXP bexarotene results in increased expression of GPX4 mRNA CTD PMID:16648578 NCBI chr 7:12,516,357...12,519,154
Ensembl chr 7:12,516,352...12,519,154
JBrowse link
G Grin2c glutamate ionotropic receptor NMDA type subunit 2C increases expression EXP bexarotene results in increased expression of GRIN2C mRNA CTD PMID:17630414 NCBI chr10:103,798,290...103,816,923
Ensembl chr10:103,798,291...103,816,287
JBrowse link
G Grina glutamate ionotropic receptor NMDA type subunit associated protein 1 increases expression EXP bexarotene results in increased expression of GRINA mRNA CTD PMID:16648578 NCBI chr 7:117,304,742...117,307,916
Ensembl chr 7:117,304,742...117,307,916
JBrowse link
G Grk2 G protein-coupled receptor kinase 2 increases expression EXP bexarotene results in increased expression of GRK2 mRNA CTD PMID:16648578 NCBI chr 1:219,536,220...219,544,329
Ensembl chr 1:219,536,220...219,544,328
JBrowse link
G Gsta5 glutathione S-transferase alpha 5 increases expression EXP bexarotene results in increased expression of GSTA5 mRNA CTD PMID:23292798 NCBI chr 8:85,553,659...85,564,914
Ensembl chr 8:85,553,734...85,565,179
JBrowse link
G Gstm3l glutathione S-transferase mu 3-like increases expression EXP bexarotene results in increased expression of GSTM5 mRNA CTD PMID:17630414 NCBI chr 2:210,761,729...210,766,501
Ensembl chr 2:210,761,729...210,766,501
JBrowse link
G Gys2 glycogen synthase 2 decreases expression
increases expression
EXP bexarotene results in decreased expression of GYS2 mRNA
bexarotene results in increased expression of GYS2 mRNA
CTD PMID:16648578, PMID:23292798 NCBI chr 4:176,638,632...176,679,805
Ensembl chr 4:176,638,629...176,679,815
JBrowse link
G H2az1 H2A.Z variant histone 1 decreases expression EXP Bexarotene results in decreased expression of H2AZ1 mRNA CTD PMID:16648578 NCBI chr 2:243,105,224...243,107,333
Ensembl chr 2:243,105,674...243,106,956
JBrowse link
G Hao2 hydroxyacid oxidase 2 decreases expression EXP bexarotene results in decreased expression of HAO2 mRNA CTD PMID:17630414 NCBI chr 2:200,785,492...200,808,868
Ensembl chr 2:200,778,122...200,808,857
JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 decreases expression ISO bexarotene results in decreased expression of HERPUD1 mRNA CTD PMID:17178900 NCBI chr19:11,046,905...11,057,440
Ensembl chr19:11,046,909...11,057,254
JBrowse link
G Hmgb2 high mobility group box 2 decreases expression EXP bexarotene results in decreased expression of HMGB2 mRNA CTD PMID:16648578 NCBI chr16:36,077,615...36,080,191
Ensembl chr16:36,077,617...36,080,191
Ensembl chr11:36,077,617...36,080,191
JBrowse link
G Homer1 homer scaffold protein 1 increases expression EXP bexarotene results in increased expression of HOMER1 mRNA CTD PMID:16648578 NCBI chr 2:22,909,550...23,012,303
Ensembl chr 2:22,909,569...23,009,678
JBrowse link
G Hp haptoglobin decreases expression EXP bexarotene results in decreased expression of HP mRNA CTD PMID:16648578 NCBI chr19:42,096,255...42,100,805
Ensembl chr19:42,097,995...42,100,804
JBrowse link
G Hpgds hematopoietic prostaglandin D synthase increases expression EXP bexarotene results in increased expression of HPGDS mRNA CTD PMID:16648578 NCBI chr 4:95,945,356...95,970,666
Ensembl chr 4:95,946,025...95,970,666
JBrowse link
G Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 increases expression
multiple interactions
ISO Bexarotene results in increased expression of HSD11B2 mRNA
Bexarotene results in increased expression of and results in increased activity of HSD11B2 protein; Cycloheximide promotes the reaction [Bexarotene results in increased expression of HSD11B2 mRNA]; Dactinomycin inhibits the reaction [Bexarotene results in increased expression of HSD11B2 mRNA]; LG 100754 inhibits the reaction [Bexarotene results in increased activity of HSD11B2 protein]; RXRA protein affects the reaction [Bexarotene results in increased expression of HSD11B2 mRNA]; RXRA protein affects the reaction [Bexarotene results in increased expression of HSD11B2 protein]
CTD PMID:31927052 NCBI chr19:37,476,083...37,481,326
Ensembl chr19:37,476,095...37,481,307
JBrowse link
G Hsd17b12 hydroxysteroid (17-beta) dehydrogenase 12 increases expression EXP bexarotene results in increased expression of HSD17B12 mRNA CTD PMID:16648578 NCBI chr 3:82,924,699...83,048,465
Ensembl chr 3:82,924,687...83,048,435
JBrowse link
G Hsd17b2 hydroxysteroid (17-beta) dehydrogenase 2 decreases expression EXP bexarotene results in decreased expression of HSD17B2 mRNA CTD PMID:16648578 NCBI chr19:50,246,404...50,317,892
Ensembl chr19:50,246,402...50,317,891
JBrowse link
G Hspa4 heat shock protein family A (Hsp70) member 4 decreases expression EXP bexarotene results in decreased expression of HSPA4 mRNA CTD PMID:16648578 NCBI chr10:38,601,624...38,642,397
Ensembl chr10:38,601,624...38,642,397
JBrowse link
G Hspa9 heat shock protein family A (Hsp70) member 9 increases expression EXP bexarotene results in increased expression of HSPA9 mRNA CTD PMID:16648578 NCBI chr18:27,731,072...27,749,235
Ensembl chr18:27,731,072...27,749,235
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 increases expression EXP bexarotene results in increased expression of HSPB1 mRNA CTD PMID:16648578 NCBI chr12:23,839,390...23,841,051
Ensembl chr12:23,839,399...23,841,049
JBrowse link
G Hsph1 heat shock protein family H (Hsp110) member 1 decreases expression EXP bexarotene results in decreased expression of HSPH1 mRNA CTD PMID:16648578 NCBI chr12:6,322,685...6,341,898
Ensembl chr12:6,322,668...6,341,902
JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein increases expression ISO bexarotene results in increased expression of ID1 mRNA; bexarotene results in increased expression of ID1 protein CTD PMID:17178900 NCBI chr 3:148,214,623...148,216,715
Ensembl chr 3:148,215,540...148,216,718
JBrowse link
G Ier2 immediate early response 2 decreases expression ISO bexarotene results in decreased expression of IER2 mRNA CTD PMID:17178900 NCBI chr19:25,774,146...25,775,670
Ensembl chr19:25,774,143...25,775,659
JBrowse link
G Ifitm2 interferon induced transmembrane protein 2 multiple interactions EXP [Bexarotene co-treated with Tamoxifen] results in decreased expression of IFITM1 mRNA CTD PMID:17630414 NCBI chr 1:213,750,219...213,751,399
Ensembl chr 1:213,750,192...213,751,405
JBrowse link
G Ifngr1 interferon gamma receptor 1 increases expression EXP bexarotene results in increased expression of IFNGR1 mRNA CTD PMID:16648578 NCBI chr 1:15,062,380...15,080,815
Ensembl chr 1:15,062,432...15,080,907
JBrowse link
G Igf1 insulin-like growth factor 1 decreases expression EXP bexarotene results in decreased expression of IGF1 protein CTD PMID:15591091 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Igf2 insulin-like growth factor 2 increases expression EXP bexarotene results in increased expression of IGF2 mRNA CTD PMID:16648578 NCBI chr 1:215,828,102...215,839,081
Ensembl chr 1:215,828,102...215,846,911
JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 increases expression EXP bexarotene results in increased expression of IGFBP1 mRNA CTD PMID:16648578 NCBI chr14:87,448,716...87,453,783
Ensembl chr14:87,448,692...87,453,785
JBrowse link
G Igfbp2 insulin-like growth factor binding protein 2 increases expression
multiple interactions
EXP bexarotene results in increased expression of IGFBP2 mRNA
[Tamoxifen co-treated with bexarotene] results in increased expression of IGFBP2 mRNA
CTD PMID:16648578, PMID:17630414 NCBI chr 9:80,118,029...80,144,804
Ensembl chr 9:80,118,029...80,144,789
JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 multiple interactions
decreases expression
EXP [bexarotene co-treated with Tamoxifen] results in decreased expression of IGFBP3 mRNA
bexarotene results in decreased expression of IGFBP3 mRNA
CTD PMID:16648578, PMID:17630414 NCBI chr14:87,457,647...87,465,374
Ensembl chr14:87,457,647...87,465,374
JBrowse link
G Igfbp6 insulin-like growth factor binding protein 6 increases expression ISO bexarotene results in increased expression of IGFBP6 mRNA; bexarotene results in increased expression of IGFBP6 protein CTD PMID:17178900 NCBI chr 7:143,749,385...143,754,018
Ensembl chr 7:143,749,221...143,754,054
JBrowse link
G Igfbp7 insulin-like growth factor binding protein 7 multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in decreased expression of IGFBP7 mRNA CTD PMID:17630414 NCBI chr14:33,010,300...33,070,193
Ensembl chr14:33,010,300...33,070,190
JBrowse link
G Il15 interleukin 15 increases expression ISO bexarotene results in increased expression of IL15 mRNA CTD PMID:17178900 NCBI chr19:23,542,606...23,624,366
Ensembl chr19:23,542,889...23,554,594
JBrowse link
G Il18 interleukin 18 decreases expression EXP bexarotene results in decreased expression of IL18 mRNA CTD PMID:16648578 NCBI chr 8:55,009,666...55,016,286
Ensembl chr 8:54,993,859...55,016,299
JBrowse link
G Il4 interleukin 4 decreases expression ISO bexarotene results in decreased expression of IL4 protein CTD PMID:15781672 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Il6r interleukin 6 receptor decreases expression EXP bexarotene results in decreased expression of IL6RA mRNA CTD PMID:16648578 NCBI chr 2:189,196,180...189,255,987
Ensembl chr 2:189,205,701...189,254,628
JBrowse link
G Ins2 insulin 2 multiple interactions ISO [bexarotene co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 protein; bexarotene inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; bexarotene inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of DMP1 mRNA]; bexarotene inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA]; bexarotene promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of NR1H3 mRNA]; bexarotene promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SREBF1 mRNA]
[[Dexamethasone co-treated with INS protein co-treated with 1-Methyl-3-isobutylxanthine] co-treated with bexarotene] results in increased expression of SLC27A1 mRNA; [Dexamethasone co-treated with INS protein co-treated with 1-Methyl-3-isobutylxanthine] results in increased susceptibility to bexarotene
CTD PMID:10777552, PMID:25932594 NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034
JBrowse link
G Insig1 insulin induced gene 1 increases expression EXP bexarotene results in increased expression of INSIG1 mRNA CTD PMID:16648578 NCBI chr 4:342,302...350,515
Ensembl chr 4:342,302...350,515
JBrowse link
G Insrr insulin receptor-related receptor increases expression EXP bexarotene results in increased expression of INSRR mRNA CTD PMID:16648578 NCBI chr 2:187,161,817...187,181,400
Ensembl chr 2:187,162,017...187,181,395
JBrowse link
G Irf1 interferon regulatory factor 1 increases expression EXP bexarotene results in increased expression of IRF1 mRNA CTD PMID:16648578 NCBI chr10:39,109,530...39,116,532
Ensembl chr10:39,109,522...39,116,531
JBrowse link
G Itga7 integrin subunit alpha 7 decreases expression EXP bexarotene results in decreased expression of ITGA7 mRNA CTD PMID:16648578 NCBI chr 7:3,355,079...3,383,886
Ensembl chr 7:3,355,116...3,384,675
JBrowse link
G Itgb6 integrin subunit beta 6 increases expression ISO bexarotene results in increased expression of ITGB6 mRNA CTD PMID:17178900 NCBI chr 3:46,652,624...46,775,362
Ensembl chr 3:46,652,623...46,726,958
JBrowse link
G Itih3 inter-alpha trypsin inhibitor, heavy chain 3 decreases expression EXP bexarotene results in decreased expression of ITIH3 mRNA CTD PMID:16648578 NCBI chr16:6,983,779...7,007,288
Ensembl chr16:6,992,062...7,007,287
JBrowse link
G Itm2a integral membrane protein 2A increases expression ISO bexarotene results in increased expression of ITM2A mRNA CTD PMID:17178900 NCBI chr  X:78,490,872...78,496,814
Ensembl chr  X:78,490,866...78,496,847
JBrowse link
G Itpr1 inositol 1,4,5-trisphosphate receptor, type 1 increases expression ISO bexarotene results in increased expression of ITPR1 mRNA CTD PMID:17178900 NCBI chr 4:140,247,297...140,580,749
Ensembl chr 4:140,247,313...140,580,748
JBrowse link
G Ivl involucrin decreases expression ISO bexarotene results in decreased expression of IVL mRNA CTD PMID:8853895 NCBI chr 2:192,761,171...192,773,346
Ensembl chr 2:192,761,538...192,763,577
JBrowse link
G Jup junction plakoglobin increases expression EXP bexarotene results in increased expression of JUP mRNA CTD PMID:16648578 NCBI chr10:88,280,517...88,307,451
Ensembl chr10:88,279,632...88,307,412
JBrowse link
G Kcnma1 potassium calcium-activated channel subfamily M alpha 1 multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in decreased expression of KCNMA1 mRNA CTD PMID:17630414 NCBI chr15:344,204...1,048,849
Ensembl chr15:344,360...1,047,956
JBrowse link
G Kcnt1 potassium sodium-activated channel subfamily T member 1 increases expression EXP bexarotene results in increased expression of KCNT1 mRNA CTD PMID:16648578 NCBI chr 3:3,310,641...3,366,558
Ensembl chr 3:3,310,954...3,365,340
JBrowse link
G Klf10 Kruppel-like factor 10 decreases expression ISO bexarotene results in decreased expression of KLF10 mRNA CTD PMID:17178900 NCBI chr 7:77,156,010...77,162,096
Ensembl chr 7:77,156,006...77,162,148
JBrowse link
G Klf9 Kruppel-like factor 9 increases expression
decreases expression
ISO
EXP
bexarotene results in increased expression of KLF9 mRNA
bexarotene results in decreased expression of KLF9 mRNA
CTD PMID:16648578, PMID:26096596 NCBI chr 1:240,908,483...240,933,198
Ensembl chr 1:240,908,483...240,933,198
JBrowse link
G Kng2 kininogen 2 increases expression
decreases expression
ISO
EXP
bexarotene results in increased expression of KNG1 mRNA
bexarotene results in decreased expression of KNG1 mRNA
CTD PMID:16648578, PMID:17849452 NCBI chr11:81,509,185...81,516,759 JBrowse link
G Krt14 keratin 14 decreases expression ISO bexarotene results in decreased expression of KRT14 mRNA CTD PMID:8853895 NCBI chr10:88,118,029...88,122,233
Ensembl chr10:88,055,823...88,122,233
JBrowse link
G Krt15 keratin 15 increases expression ISO bexarotene results in increased expression of KRT15 mRNA CTD PMID:17178900 NCBI chr10:88,046,803...88,050,622
Ensembl chr10:88,046,803...88,050,622
JBrowse link
G Krt17 keratin 17 decreases expression ISO bexarotene results in decreased expression of KRT17 mRNA; bexarotene results in decreased expression of KRT17 protein CTD PMID:17178900 NCBI chr10:88,158,993...88,163,712
Ensembl chr10:88,118,001...88,163,723
JBrowse link
G Krt5 keratin 5 decreases expression ISO bexarotene results in decreased expression of KRT5 mRNA CTD PMID:8853895 NCBI chr 7:143,320,142...143,324,536
Ensembl chr 7:143,316,920...143,453,546
JBrowse link
G Ldhb lactate dehydrogenase B decreases expression EXP bexarotene results in decreased expression of LDHB mRNA CTD PMID:16648578 NCBI chr 4:176,701,980...176,719,999
Ensembl chr 4:176,701,983...176,720,012
JBrowse link
G Lgals3 galectin 3 decreases expression EXP bexarotene results in decreased expression of LGALS3 mRNA CTD PMID:16648578 NCBI chr15:24,153,602...24,165,537
Ensembl chr15:24,141,651...24,165,537
JBrowse link
G Lgals5 galectin 5 increases expression EXP bexarotene results in increased expression of LGALS5 mRNA CTD PMID:16648578 NCBI chr10:66,226,015...66,229,293
Ensembl chr10:66,225,995...66,229,311
JBrowse link
G Lifr LIF receptor subunit alpha multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in decreased expression of LIFR mRNA CTD PMID:17630414 NCBI chr 2:56,424,910...56,489,346
Ensembl chr 2:56,426,367...56,489,415
JBrowse link
G Lipa lipase A, lysosomal acid type decreases expression EXP bexarotene results in decreased expression of LIP1 mRNA CTD PMID:16648578 NCBI chr 1:252,816,536...252,959,348
Ensembl chr 1:252,816,527...252,849,904
JBrowse link
G Lipe lipase E, hormone sensitive type decreases expression EXP bexarotene results in decreased expression of LIPE mRNA CTD PMID:16648578 NCBI chr 1:82,248,031...82,266,727
Ensembl chr 1:82,248,046...82,266,727
JBrowse link
G Lman1 lectin, mannose-binding, 1 decreases expression EXP bexarotene results in decreased expression of LMAN1 mRNA CTD PMID:16648578 NCBI chr18:61,683,377...61,707,344
Ensembl chr18:61,685,117...61,707,317
JBrowse link
G Lox lysyl oxidase decreases expression EXP bexarotene results in decreased expression of LOX mRNA CTD PMID:16648578 NCBI chr18:47,500,320...47,577,819
Ensembl chr18:47,500,330...47,577,819
JBrowse link
G Loxl2 lysyl oxidase-like 2 increases expression ISO bexarotene results in increased expression of LOXL2 mRNA CTD PMID:17178900 NCBI chr15:51,276,022...51,365,238
Ensembl chr15:51,303,909...51,365,234
JBrowse link
G Lre3 LINE retrotransposable element 3 increases expression EXP bexarotene results in increased expression of LRE3 mRNA CTD PMID:16648578
G Lrg1 leucine-rich alpha-2-glycoprotein 1 multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in decreased expression of LRG1 mRNA CTD PMID:17630414 NCBI chr 9:10,952,424...10,954,664
Ensembl chr 9:10,952,374...10,954,681
JBrowse link
G Lrp2 LDL receptor related protein 2 decreases expression EXP bexarotene results in decreased expression of LRP2 mRNA CTD PMID:16648578 NCBI chr 3:55,665,153...55,822,484
Ensembl chr 3:55,665,145...55,822,551
JBrowse link
G Lum lumican decreases expression EXP bexarotene results in decreased expression of LUM mRNA CTD PMID:16648578 NCBI chr 7:38,820,058...38,826,862
Ensembl chr 7:38,819,771...38,826,862
JBrowse link
G Lypla1 lysophospholipase 1 decreases expression EXP bexarotene results in decreased expression of LYPLA1 mRNA CTD PMID:16648578 NCBI chr 5:14,559,333...14,588,447
Ensembl chr 5:14,559,334...14,588,422
JBrowse link
G Lyst lysosomal trafficking regulator increases expression EXP bexarotene results in increased expression of LYST mRNA CTD PMID:17630414 NCBI chr17:90,323,055...90,522,091 JBrowse link
G Lyve1 lymphatic vessel endothelial hyaluronan receptor 1 multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in decreased expression of XLKD1 mRNA CTD PMID:17630414 NCBI chr 1:175,663,266...175,676,699
Ensembl chr 1:175,663,266...175,676,699
JBrowse link
G Maf MAF bZIP transcription factor increases expression ISO bexarotene results in increased expression of MAF mRNA CTD PMID:17178900 NCBI chr19:48,179,826...48,200,995
Ensembl chr19:48,194,804...48,196,748
JBrowse link
G Maff MAF bZIP transcription factor F decreases expression ISO bexarotene results in decreased expression of MAFF mRNA CTD PMID:17178900 NCBI chr 7:120,580,743...120,592,095
Ensembl chr 7:120,580,743...120,592,095
JBrowse link
G Maob monoamine oxidase B decreases expression EXP bexarotene results in decreased expression of MAOB mRNA CTD PMID:16648578 NCBI chr  X:6,430,694...6,533,520
Ensembl chr  X:6,430,594...6,533,534
JBrowse link
G Map1b microtubule-associated protein 1B increases expression EXP bexarotene results in increased expression of MAP1B mRNA CTD PMID:16648578 NCBI chr 2:29,675,391...29,768,750
Ensembl chr 2:29,675,391...29,768,750
JBrowse link
G Map2 microtubule-associated protein 2 increases expression EXP bexarotene results in increased expression of MAP2 mRNA CTD PMID:16648578 NCBI chr 9:73,204,753...73,462,965
Ensembl chr 9:73,319,710...73,462,972
JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 increases expression EXP bexarotene results in increased expression of MAP3K1 mRNA CTD PMID:16648578 NCBI chr 2:43,329,516...43,393,203
Ensembl chr 2:43,329,516...43,393,207
JBrowse link
G Map3k12 mitogen activated protein kinase kinase kinase 12 increases expression EXP bexarotene results in increased expression of MAP3K12 mRNA CTD PMID:16648578 NCBI chr 7:144,102,275...144,120,306
Ensembl chr 7:144,102,680...144,109,116
JBrowse link
G Mark1 microtubule affinity regulating kinase 1 increases expression EXP bexarotene results in increased expression of MARK1 mRNA CTD PMID:16648578 NCBI chr13:102,808,254...102,942,863
Ensembl chr13:102,808,253...102,942,863
JBrowse link
G Me1 malic enzyme 1 increases expression EXP bexarotene results in increased expression of ME1 mRNA CTD PMID:16648578, PMID:23292798 NCBI chr 8:94,256,830...94,368,834
Ensembl chr 8:94,256,839...94,368,834
JBrowse link
G Mfsd2a major facilitator superfamily domain containing 2A decreases expression EXP bexarotene results in decreased expression of MFSD2A mRNA CTD PMID:17630414 NCBI chr 5:140,642,865...140,657,759
Ensembl chr 5:140,642,885...140,657,745
JBrowse link
G Mgp matrix Gla protein multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in decreased expression of MGP mRNA CTD PMID:17630414 NCBI chr 4:170,856,783...170,860,105
Ensembl chr 4:170,856,751...170,860,225
JBrowse link
G Mllt11 MLLT11, transcription factor 7 cofactor increases expression ISO bexarotene results in increased expression of MLLT11 mRNA CTD PMID:17178900 NCBI chr 2:196,392,936...196,402,106
Ensembl chr 2:196,392,938...196,402,106
JBrowse link
G Mlxipl MLX interacting protein-like multiple interactions ISO [Bexarotene co-treated with GW 3965] results in decreased expression of MLXIPL mRNA; [Bexarotene co-treated with TO-901317] results in decreased expression of MLXIPL mRNA CTD PMID:32123961 NCBI chr12:24,590,645...24,619,639 JBrowse link
G Mmp1 matrix metallopeptidase 1 decreases expression ISO bexarotene results in decreased expression of MMP1 mRNA CTD PMID:17178900 NCBI chr 8:5,703,206...5,723,593
Ensembl chr 8:5,703,206...5,723,591
JBrowse link
G Mmp14 matrix metallopeptidase 14 decreases expression EXP bexarotene results in decreased expression of MMP14 mRNA CTD PMID:16648578 NCBI chr15:33,074,441...33,083,666
Ensembl chr15:33,074,441...33,083,655
JBrowse link
G Mrc1 mannose receptor, C type 1 multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in decreased expression of MRC1 mRNA CTD PMID:17630414 NCBI chr17:81,352,700...81,433,743
Ensembl chr17:81,352,700...81,433,743
JBrowse link
G Mt-co2 mitochondrially encoded cytochrome c oxidase II decreases expression ISO bexarotene results in decreased expression of COX2 mRNA; bexarotene results in decreased expression of COX2 protein CTD PMID:17178900 NCBI chr MT:7,006...7,689
Ensembl chr MT:7,006...7,689
JBrowse link
G Mthfd2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase decreases expression ISO bexarotene results in decreased expression of MTHFD2 mRNA CTD PMID:17178900 NCBI chr 4:115,004,433...115,015,965
Ensembl chr 4:115,004,448...115,015,965
JBrowse link
G Muc1 mucin 1, cell surface associated increases expression EXP bexarotene results in increased expression of MUC1 mRNA CTD PMID:16648578 NCBI chr 2:188,543,137...188,547,874
Ensembl chr 2:188,543,137...188,547,874
JBrowse link
G Mug1 murinoglobulin 1 decreases expression EXP bexarotene results in decreased expression of MUG1 mRNA CTD PMID:16648578 NCBI chr 4:154,676,382...154,729,288
Ensembl chr 4:154,391,647...154,729,310
JBrowse link
G Napa NSF attachment protein alpha increases expression EXP bexarotene results in increased expression of NAPA mRNA CTD PMID:16648578 NCBI chr 1:77,994,227...78,012,846
Ensembl chr 1:77,994,203...78,012,845
JBrowse link
G Nat8 N-acetyltransferase 8 decreases expression EXP bexarotene results in decreased expression of NAT8 mRNA CTD PMID:17630414 NCBI chr 4:117,525,963...117,527,443 JBrowse link
G Ndufaf3 NADH:ubiquinone oxidoreductase complex assembly factor 3 increases expression EXP bexarotene results in increased expression of NDUFAF3 mRNA CTD PMID:16648578 NCBI chr 8:117,351,628...117,353,460
Ensembl chr 8:117,351,629...117,353,672
JBrowse link
G Neurod2 neuronal differentiation 2 increases expression EXP bexarotene results in increased expression of NEUROD2 mRNA CTD PMID:16648578 NCBI chr10:86,280,865...86,282,681
Ensembl chr10:86,280,892...86,282,693
JBrowse link
G Nim1k NIM1 serine/threonine protein kinase multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in increased expression of NIM1K mRNA CTD PMID:17630414 NCBI chr 2:52,448,746...52,494,137
Ensembl chr 2:52,448,715...52,492,509
JBrowse link
G Nol3 nucleolar protein 3 multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in increased expression of NOL3 mRNA CTD PMID:17630414 NCBI chr19:37,232,567...37,236,668
Ensembl chr19:37,235,001...37,236,649
JBrowse link
G Nos2 nitric oxide synthase 2 decreases expression ISO bexarotene results in decreased expression of NOS2 mRNA CTD PMID:17849452 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Npy neuropeptide Y increases expression EXP bexarotene results in increased expression of NPY mRNA CTD PMID:17630414 NCBI chr 4:79,557,856...79,565,059
Ensembl chr 4:79,557,854...79,565,097
JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 increases expression
multiple interactions
EXP
ISO
bexarotene results in increased expression of NR0B2 mRNA
[Bexarotene co-treated with GW 3965] results in increased expression of NR0B2 mRNA; [Bexarotene co-treated with paxilline] results in increased expression of NR0B2 mRNA; [Bexarotene co-treated with TO-901317] results in increased expression of NR0B2 mRNA
Bexarotene results in increased expression of NR0B2 mRNA
CTD PMID:17630414, PMID:23292798, PMID:32123961 NCBI chr 5:151,776,004...151,779,319
Ensembl chr 5:151,776,004...151,779,319
JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 multiple interactions
decreases expression
ISO [Bexarotene co-treated with GW 3965] results in increased expression of NR1H3 mRNA; [Bexarotene co-treated with paxilline] results in increased expression of NR1H3 mRNA; [Bexarotene co-treated with TO-901317] results in increased expression of NR1H3 mRNA; Bexarotene promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of NR1H3 mRNA]
Bexarotene results in decreased expression of NR1H3 mRNA
CTD PMID:25932594, PMID:32123961 NCBI chr 3:80,004,130...80,014,197
Ensembl chr 3:80,004,130...80,012,750
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases expression
multiple interactions
EXP
ISO
bexarotene results in increased expression of NR1I3 mRNA
Bexarotene binds to and results in increased activity of NR1I3 protein alternative form
CTD PMID:17630414, PMID:31312845 NCBI chr13:89,585,072...89,591,278
Ensembl chr13:89,586,283...89,591,277
JBrowse link
G Nrip1 nuclear receptor interacting protein 1 multiple interactions ISO [Bexarotene co-treated with GW 3965] results in increased expression of NRIP1 mRNA; [Bexarotene co-treated with TO-901317] results in increased expression of NRIP1 mRNA CTD PMID:32123961 NCBI chr11:14,658,225...14,742,478
Ensembl chr11:14,658,225...14,741,563
JBrowse link
G Oaz1 ornithine decarboxylase antizyme 1 increases expression EXP bexarotene results in increased expression of OAZ1 mRNA CTD PMID:16648578 NCBI chr 7:11,752,127...11,754,587
Ensembl chr 7:11,752,412...11,754,508
JBrowse link
G Odc1 ornithine decarboxylase 1 decreases expression ISO bexarotene results in decreased expression of ODC1 mRNA CTD PMID:17178900 NCBI chr 6:42,852,529...42,859,142
Ensembl chr 6:42,852,683...42,859,927
JBrowse link
G Odf3b outer dense fiber of sperm tails 3B multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in increased expression of ODF3B mRNA CTD PMID:17630414 NCBI chr 7:130,347,945...130,351,573
Ensembl chr 7:130,347,945...130,350,570
JBrowse link
G Olr1280 olfactory receptor 1280 increases expression EXP bexarotene results in increased expression of OLR1280 mRNA CTD PMID:16648578 NCBI chr 2:115,074,344...115,075,303
Ensembl chr 2:115,074,344...115,075,303
JBrowse link
G Orm1 orosomucoid 1 decreases expression EXP bexarotene results in decreased expression of ORM1 mRNA CTD PMID:16648578 NCBI chr 5:79,179,668...79,182,820
Ensembl chr 5:79,179,417...79,182,820
JBrowse link
G P4hb prolyl 4-hydroxylase subunit beta increases expression EXP bexarotene results in increased expression of P4HB mRNA CTD PMID:16648578 NCBI chr10:109,736,459...109,748,070
Ensembl chr10:109,736,458...109,747,987
JBrowse link
G Pde2a phosphodiesterase 2A decreases expression EXP bexarotene results in decreased expression of PDE2A mRNA CTD PMID:16648578 NCBI chr 1:166,534,643...166,626,158
Ensembl chr 1:166,534,643...166,626,158
JBrowse link
G Pdk2 pyruvate dehydrogenase kinase 2 increases expression EXP bexarotene results in increased expression of PDK2 mRNA CTD PMID:16648578 NCBI chr10:82,838,270...82,852,758
Ensembl chr10:82,839,153...82,852,660
JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 increases expression EXP bexarotene results in increased expression of PDK4 mRNA CTD PMID:16648578 NCBI chr 4:30,546,772...30,556,774
Ensembl chr 4:30,546,664...30,556,814
JBrowse link
G Per2 period circadian regulator 2 decreases expression ISO bexarotene results in decreased expression of PER2 mRNA CTD PMID:17178900 NCBI chr 9:98,555,154...98,597,362
Ensembl chr 9:98,555,169...98,597,359
JBrowse link
G Pex11a peroxisomal biogenesis factor 11 alpha multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in increased expression of PEX11A mRNA CTD PMID:17630414 NCBI chr 1:141,474,189...141,481,270
Ensembl chr 1:141,474,180...141,481,315
JBrowse link
G Pex19 peroxisomal biogenesis factor 19 decreases expression EXP bexarotene results in decreased expression of PEX19 mRNA CTD PMID:16648578 NCBI chr13:90,514,324...90,530,825
Ensembl chr13:90,514,336...90,530,349
JBrowse link
G Pf4 platelet factor 4 increases expression EXP bexarotene results in increased expression of PF4 mRNA CTD PMID:17630414 NCBI chr14:18,848,549...18,849,258
Ensembl chr14:18,848,549...18,849,258
JBrowse link
G Pgr progesterone receptor multiple interactions ISO bexarotene binds to and results in decreased activity of PGR protein CTD PMID:25752796 NCBI chr 8:7,128,656...7,187,796
Ensembl chr 8:7,128,656...7,187,796
JBrowse link
G Pik3cb phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta increases expression EXP bexarotene results in increased expression of PIK3CB mRNA CTD PMID:16648578 NCBI chr 8:107,275,849...107,381,088
Ensembl chr 8:107,275,725...107,380,933
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 multiple interactions ISO bexarotene promotes the reaction [rosiglitazone results in increased expression of PIK3R1 mRNA] CTD PMID:10548525 NCBI chr 2:31,742,326...31,826,882
Ensembl chr 2:31,745,088...31,826,867
JBrowse link
G Pik3r3 phosphoinositide-3-kinase regulatory subunit 3 increases expression EXP bexarotene results in increased expression of PIK3R3 mRNA CTD PMID:16648578 NCBI chr 5:135,069,972...135,145,633
Ensembl chr 5:135,074,297...135,142,488
JBrowse link
G Pkib cAMP-dependent protein kinase inhibitor beta multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in increased expression of PKIB mRNA CTD PMID:17630414 NCBI chr20:40,616,868...40,712,598
Ensembl chr20:40,618,128...40,712,592
JBrowse link
G Plagl1 PLAG1 like zinc finger 1 decreases expression EXP bexarotene results in decreased expression of PLAGL1 mRNA CTD PMID:16648578 NCBI chr 1:7,219,587...7,270,169
Ensembl chr 1:7,252,349...7,259,035
JBrowse link
G Plat plasminogen activator, tissue type increases expression ISO bexarotene results in increased expression of PLAT mRNA CTD PMID:17178900 NCBI chr16:74,098,263...74,122,897
Ensembl chr16:74,098,260...74,122,889
JBrowse link
G Plaur plasminogen activator, urokinase receptor decreases expression ISO bexarotene results in decreased expression of PLAUR mRNA CTD PMID:17178900 NCBI chr 1:81,328,171...81,344,954
Ensembl chr 1:81,328,183...81,344,708
JBrowse link
G Plin1 perilipin 1 increases expression ISO bexarotene results in increased expression of PLIN1 mRNA CTD PMID:25932594 NCBI chr 1:141,458,907...141,470,927
Ensembl chr 1:141,458,181...141,471,010
JBrowse link
G Plod2 procollagen lysine, 2-oxoglutarate 5-dioxygenase 2 increases expression ISO bexarotene results in increased expression of PLOD2 mRNA CTD PMID:17178900 NCBI chr 8:99,977,334...100,059,736
Ensembl chr 8:99,977,334...100,059,736
JBrowse link
G Pno1 partner of NOB1 homolog decreases expression ISO bexarotene results in decreased expression of PNO1 mRNA CTD PMID:17178900 NCBI chr14:100,364,192...100,372,760
Ensembl chr14:100,364,190...100,372,760
JBrowse link
G Pnrc1 proline-rich nuclear receptor coactivator 1 increases expression ISO bexarotene results in increased expression of PNRC1 mRNA CTD PMID:17178900 NCBI chr 5:48,501,472...48,504,511
Ensembl chr 5:48,501,472...48,504,511
JBrowse link
G Pola1 DNA polymerase alpha 1, catalytic subunit increases expression EXP bexarotene results in increased expression of POLA1 mRNA CTD PMID:16648578 NCBI chr  X:62,382,604...62,698,830
Ensembl chr  X:62,382,608...62,698,830
JBrowse link
G Pon1 paraoxonase 1 decreases expression EXP bexarotene results in decreased expression of PON1 mRNA CTD PMID:16648578 NCBI chr 4:30,249,749...30,276,297
Ensembl chr 4:30,249,742...30,276,372
JBrowse link
G Por cytochrome p450 oxidoreductase increases expression EXP bexarotene results in increased expression of POR mRNA CTD PMID:16648578 NCBI chr12:23,998,411...24,017,063
Ensembl chr12:23,998,411...24,046,814
JBrowse link
G Ppp2cb protein phosphatase 2 catalytic subunit beta increases expression EXP bexarotene results in increased expression of PPP2CB mRNA CTD PMID:16648578 NCBI chr16:62,273,276...62,294,767
Ensembl chr16:62,273,276...62,294,769
JBrowse link
G Ppp2r1a protein phosphatase 2 scaffold subunit A alpha increases expression EXP bexarotene results in increased expression of PPP2R1A mRNA CTD PMID:16648578 NCBI chr 1:60,717,386...60,736,629
Ensembl chr 1:60,717,386...60,736,609
JBrowse link
G Ppt1 palmitoyl-protein thioesterase 1 decreases expression EXP bexarotene results in decreased expression of PPT1 mRNA CTD PMID:16648578 NCBI chr 5:140,538,260...140,558,163
Ensembl chr 5:140,538,260...140,558,162
JBrowse link
G Prdx6 peroxiredoxin 6 increases expression EXP bexarotene results in increased expression of PRDX6 mRNA CTD PMID:16648578 NCBI chr13:79,077,567...79,088,113
Ensembl chr13:79,077,033...79,088,127
JBrowse link
G Prkar2b protein kinase cAMP-dependent type II regulatory subunit beta decreases expression EXP bexarotene results in decreased expression of PRKAR2B mRNA CTD PMID:16648578 NCBI chr 6:51,265,509...51,356,383
Ensembl chr 6:51,265,515...51,356,383
JBrowse link
G Prl8a4 prolactin family 8, subfamily a, member 4 increases expression EXP bexarotene results in increased expression of PRL8A4 mRNA CTD PMID:16648578 NCBI chr17:39,376,040...39,382,128
Ensembl chr17:39,188,311...39,463,715
JBrowse link
G Prlhr prolactin releasing hormone receptor increases expression EXP bexarotene results in increased expression of PRLHR mRNA CTD PMID:16648578 NCBI chr 1:281,754,472...281,756,159
Ensembl chr 1:281,754,724...281,756,159
JBrowse link
G Prlr prolactin receptor multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in decreased expression of PRLR mRNA CTD PMID:17630414 NCBI chr 2:60,131,410...60,325,686
Ensembl chr 2:60,131,776...60,325,692
JBrowse link
G Prnp prion protein decreases expression EXP bexarotene results in decreased expression of PRNP mRNA CTD PMID:16648578 NCBI chr 3:124,515,917...124,531,320
Ensembl chr 3:124,515,978...124,531,316
JBrowse link
G Prom1 prominin 1 multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in decreased expression of PROM1 mRNA CTD PMID:17630414 NCBI chr14:71,532,321...71,637,400
Ensembl chr14:71,533,063...71,637,417
JBrowse link
G Prr15 proline rich 15 multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in increased expression of PRR15 mRNA CTD PMID:17630414 NCBI chr 4:84,478,839...84,481,885
Ensembl chr 4:84,478,839...84,481,883
JBrowse link
G Psap prosaposin increases expression EXP bexarotene results in increased expression of PSAP mRNA CTD PMID:16648578 NCBI chr20:29,831,302...29,856,876
Ensembl chr20:29,831,314...29,856,875
JBrowse link
G Psmc2 proteasome 26S subunit, ATPase 2 increases expression EXP bexarotene results in increased expression of PSMC2 mRNA CTD PMID:16648578 NCBI chr 4:9,867,132...9,881,383
Ensembl chr 4:9,867,101...9,881,484
JBrowse link
G Psmd4 proteasome 26S subunit, non-ATPase 4 increases expression EXP bexarotene results in increased expression of PSMD4 mRNA CTD PMID:16648578 NCBI chr 2:196,198,303...196,207,569
Ensembl chr 2:196,198,038...196,207,560
JBrowse link
G Pspn persephin increases expression EXP bexarotene results in increased expression of PSPN mRNA CTD PMID:16648578 NCBI chr 9:10,044,756...10,045,314
Ensembl chr 9:10,044,756...10,045,314
JBrowse link
G Ptger3 prostaglandin E receptor 3 decreases expression ISO bexarotene results in decreased expression of PTGER3 mRNA CTD PMID:17849452 NCBI chr 2:263,895,093...263,979,682
Ensembl chr 2:263,895,241...263,979,698
JBrowse link
G Ptger4 prostaglandin E receptor 4 decreases expression ISO bexarotene results in decreased expression of PTGER4 mRNA CTD PMID:17849452 NCBI chr 2:54,951,625...54,966,470
Ensembl chr 2:54,952,821...54,963,448
JBrowse link
G Ptms parathymosin increases expression EXP bexarotene results in increased expression of PTMS mRNA CTD PMID:16648578 NCBI chr 4:157,435,371...157,439,507
Ensembl chr 4:157,435,373...157,439,507
JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C increases expression EXP bexarotene results in increased expression of PTPRC mRNA CTD PMID:16648578 NCBI chr13:55,061,561...55,174,150
Ensembl chr13:55,061,562...55,173,692
JBrowse link
G Qpct glutaminyl-peptide cyclotransferase increases expression EXP bexarotene results in increased expression of QPCT mRNA CTD PMID:16648578 NCBI chr 6:1,657,110...1,689,575
Ensembl chr 6:1,657,331...1,689,559
JBrowse link
G Rab11b RAB11B, member RAS oncogene family increases expression EXP bexarotene results in increased expression of RAB11B mRNA CTD PMID:16648578 NCBI chr 7:18,598,991...18,612,132
Ensembl chr 7:18,598,880...18,612,147
JBrowse link
G Rab7a RAB7A, member RAS oncogene family increases expression EXP bexarotene results in increased expression of RAB7 mRNA CTD PMID:16648578 NCBI chr 4:119,910,461...119,963,065
Ensembl chr 4:119,910,478...119,959,173
JBrowse link
G Rabep2 rabaptin, RAB GTPase binding effector protein 2 increases expression EXP bexarotene results in increased expression of RABEP2 mRNA CTD PMID:16648578 NCBI chr 1:197,839,583...197,855,953
Ensembl chr 1:197,839,430...197,856,312
JBrowse link
G Rarb retinoic acid receptor, beta increases expression ISO bexarotene results in increased expression of RARB mRNA CTD PMID:17178900 NCBI chr15:9,915,223...10,262,599
Ensembl chr15:10,120,206...10,262,599
JBrowse link
G Rasl11a RAS-like family 11 member A increases expression EXP bexarotene results in increased expression of RASL11A mRNA CTD PMID:16648578 NCBI chr12:9,986,150...9,990,284
Ensembl chr12:9,985,928...9,990,284
JBrowse link
G Rassf1 Ras association domain family member 1 decreases expression ISO bexarotene results in decreased expression of RASSF1 mRNA CTD PMID:17849452 NCBI chr 8:116,307,149...116,318,289
Ensembl chr 8:116,307,141...116,318,289
JBrowse link
G Rb1 RB transcriptional corepressor 1 decreases phosphorylation ISO bexarotene results in decreased phosphorylation of RB1 protein CTD PMID:16273314 NCBI chr15:55,081,582...55,209,060
Ensembl chr15:55,083,140...55,209,342
JBrowse link
G Rdh16 retinol dehydrogenase 16 increases expression EXP bexarotene results in increased expression of RDH2 mRNA CTD PMID:16648578 NCBI chr 7:71,058,150...71,072,685
Ensembl chr 7:70,980,422...71,072,689
JBrowse link
G Renbp renin binding protein increases expression EXP bexarotene results in increased expression of RENBP mRNA CTD PMID:16648578 NCBI chr  X:156,854,490...156,863,548
Ensembl chr  X:156,854,594...156,863,528
JBrowse link
G Rest RE1-silencing transcription factor increases expression EXP bexarotene results in increased expression of REST mRNA CTD PMID:16648578 NCBI chr14:33,131,985...33,152,019
Ensembl chr14:33,134,511...33,164,141
JBrowse link
G Rgn regucalcin decreases expression EXP bexarotene results in decreased expression of RGN mRNA CTD PMID:16648578 NCBI chr  X:1,833,484...1,848,904
Ensembl chr  X:1,833,492...1,848,904
JBrowse link
G Rida reactive intermediate imine deaminase A homolog decreases expression EXP bexarotene results in decreased expression of RIDA mRNA CTD PMID:16648578 NCBI chr 7:73,256,506...73,270,308
Ensembl chr 7:73,256,508...73,270,308
JBrowse link
G Rnase1 ribonuclease A family member 1, pancreatic increases expression EXP bexarotene results in increased expression of RNASE1 mRNA CTD PMID:16648578
G Rpl18a ribosomal protein L18A increases expression EXP bexarotene results in increased expression of RPL18A mRNA CTD PMID:16648578 NCBI chr16:20,293,277...20,295,283
Ensembl chr16:20,293,229...20,295,294
JBrowse link
G Rpl22 ribosomal protein L22 increases expression EXP bexarotene results in increased expression of RPL22 mRNA CTD PMID:16648578 NCBI chr 5:169,506,150...169,512,875
Ensembl chr 5:169,506,138...169,512,871
JBrowse link
G Rpl7a ribosomal protein L7a increases expression EXP bexarotene results in increased expression of RPL7A mRNA CTD PMID:16648578 NCBI chr 3:5,458,985...5,461,627
Ensembl chr 3:5,459,160...5,461,583
Ensembl chr 3:5,459,160...5,461,583
JBrowse link
G Rps2 ribosomal protein S2 increases expression EXP bexarotene results in increased expression of RPS2 mRNA CTD PMID:16648578 NCBI chr10:14,088,171...14,090,020
Ensembl chr10:14,088,319...14,089,979
JBrowse link
G Rpsa ribosomal protein SA increases expression EXP bexarotene results in increased expression of RPSA mRNA CTD PMID:16648578 NCBI chr 8:128,806,053...128,809,987
Ensembl chr 8:128,806,129...128,809,986
JBrowse link
G RT1-Ba RT1 class II, locus Ba multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in decreased expression of RT1-BA mRNA CTD PMID:17630414 NCBI chr20:4,066,133...4,070,726
Ensembl chr20:4,066,132...4,070,721
JBrowse link
G RT1-Cl RT1 class Ib, locus Cl increases expression EXP bexarotene results in increased expression of RT1-CL mRNA CTD PMID:16648578
G RT1-Da RT1 class II, locus Da multiple interactions
increases expression
EXP [bexarotene co-treated with Tamoxifen] results in decreased expression of RT1-DA mRNA
bexarotene results in increased expression of RT1-DA mRNA
CTD PMID:16648578, PMID:17630414 NCBI chr20:4,127,644...4,132,616
Ensembl chr20:4,127,644...4,132,616
JBrowse link
G RT1-Db1 RT1 class II, locus Db1 multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in decreased expression of RT1-DB1 mRNA CTD PMID:17630414 NCBI chr20:4,087,621...4,097,190
Ensembl chr20:4,087,618...4,097,190
JBrowse link
G RT1-EC2 RT1 class Ib, locus EC2 increases expression EXP bexarotene results in increased expression of RT1-EC2 mRNA CTD PMID:16648578
G Rtn4 reticulon 4 increases expression EXP bexarotene results in increased expression of RTN4 mRNA CTD PMID:17630414 NCBI chr14:114,126,931...114,174,459
Ensembl chr14:114,126,943...114,174,458
JBrowse link
G Rxra retinoid X receptor alpha affects binding
multiple interactions
ISO Bexarotene binds to RXRA protein
Bexarotene binds to and results in increased activity of RXRA protein; RXRA promotes the reaction [Bexarotene results in increased expression of APOA2 mRNA]; RXRA protein affects the reaction [Bexarotene results in increased expression of CYP2B6 mRNA]; RXRA protein affects the reaction [Bexarotene results in increased expression of HSD11B2 mRNA]; RXRA protein affects the reaction [Bexarotene results in increased expression of HSD11B2 protein]
CTD PMID:8668150, PMID:21218783, PMID:23843199, PMID:31312845, PMID:31566444, PMID:31927052 NCBI chr 3:6,272,560...6,295,354
Ensembl chr 3:6,211,789...6,295,908
JBrowse link
G Rxrb retinoid X receptor beta affects binding ISO bexarotene binds to RXRB protein CTD PMID:23843199 NCBI chr20:3,822,673...3,829,138
Ensembl chr20:3,823,042...3,829,140
JBrowse link
G Rxrg retinoid X receptor gamma affects binding
decreases expression
ISO bexarotene binds to RXRG protein
bexarotene results in decreased expression of RXRG mRNA
CTD PMID:17849452, PMID:23843199 NCBI chr13:85,818,473...85,868,555
Ensembl chr13:85,818,427...85,868,552
JBrowse link
G S100a10 S100 calcium binding protein A10 decreases expression EXP bexarotene results in decreased expression of S100A10 mRNA CTD PMID:16648578 NCBI chr 2:193,892,589...193,901,236
Ensembl chr 2:193,892,589...193,901,236
JBrowse link
G S100a9 S100 calcium binding protein A9 increases expression ISO
EXP
bexarotene results in increased expression of S100A9 mRNA CTD PMID:16648578, PMID:17178900 NCBI chr 2:190,097,436...190,100,209
Ensembl chr 2:190,097,554...190,100,276
JBrowse link
G S100b S100 calcium binding protein B decreases expression EXP bexarotene results in decreased expression of S100B mRNA CTD PMID:16648578 NCBI chr20:13,130,633...13,142,856
Ensembl chr20:13,130,636...13,142,856
JBrowse link
G Scd stearoyl-CoA desaturase increases expression
multiple interactions
ISO
EXP
bexarotene results in increased expression of SCD1 mRNA
[Bexarotene co-treated with GW 3965] results in increased expression of SCD mRNA; [Bexarotene co-treated with TO-901317] results in increased expression of SCD mRNA
[Tamoxifen co-treated with bexarotene] results in increased expression of SCD1 mRNA
Bexarotene results in increased expression of SCD mRNA
CTD PMID:17178900, PMID:17630414, PMID:23292798, PMID:32123961 NCBI chr 1:264,159,966...264,173,061
Ensembl chr 1:264,160,129...264,172,729
JBrowse link
G Scd2 stearoyl-Coenzyme A desaturase 2 increases expression EXP bexarotene results in increased expression of SCD2 mRNA CTD PMID:16648578, PMID:17630414 NCBI chr 1:264,059,374...264,072,433
Ensembl chr 1:264,059,374...264,072,433
JBrowse link
G Scp2 sterol carrier protein 2 decreases expression EXP bexarotene results in decreased expression of SCP2 mRNA CTD PMID:16648578 NCBI chr 5:127,647,934...127,735,703
Ensembl chr 5:127,620,274...127,735,739
JBrowse link
G Sdc2 syndecan 2 decreases expression EXP bexarotene results in decreased expression of SDC2 mRNA CTD PMID:16648578 NCBI chr 7:71,572,731...71,686,139
Ensembl chr 7:71,572,941...71,686,044
JBrowse link
G Serpina1 serpin family A member 1 decreases expression EXP bexarotene results in decreased expression of SERPINA1 mRNA CTD PMID:16648578 NCBI chr 6:127,610,241...127,632,265
Ensembl chr 6:127,610,243...127,632,265
JBrowse link
G Serpina3n serine (or cysteine) peptidase inhibitor, clade A, member 3N decreases expression EXP bexarotene results in decreased expression of SERPINA3N mRNA CTD PMID:16648578 NCBI chr 6:128,073,344...128,080,878
Ensembl chr 6:127,941,526...128,080,889
JBrowse link
G Serpind1 serpin family D member 1 decreases expression EXP bexarotene results in decreased expression of SERPIND1 mRNA CTD PMID:16648578 NCBI chr11:87,913,814...87,924,880
Ensembl chr11:87,913,806...87,924,816
JBrowse link
G Serpinh1 serpin family H member 1 increases expression EXP bexarotene results in increased expression of SERPINH1 mRNA CTD PMID:17630414 NCBI chr 1:164,301,010...164,308,306
Ensembl chr 1:164,301,010...164,308,317
JBrowse link
G Sfpq splicing factor proline and glutamine rich decreases expression EXP bexarotene results in decreased expression of SFPQ mRNA CTD PMID:16648578 NCBI chr 5:145,079,803...145,088,517
Ensembl chr 5:145,079,803...145,088,498
JBrowse link
G Shh sonic hedgehog signaling molecule increases expression ISO bexarotene results in increased expression of SHH mRNA CTD PMID:26096596 NCBI chr 4:718,538...727,691
Ensembl chr 4:718,538...727,691
JBrowse link
G Siah2 siah E3 ubiquitin protein ligase 2 decreases expression ISO bexarotene results in decreased expression of SIAH2 mRNA CTD PMID:17178900 NCBI chr 2:148,874,151...148,891,900
Ensembl chr 2:148,874,151...148,891,900
JBrowse link
G Slc1a3 solute carrier family 1 member 3 decreases expression EXP bexarotene results in decreased expression of SLC1A3 mRNA CTD PMID:16648578 NCBI chr 2:57,860,881...57,935,363
Ensembl chr 2:57,860,834...57,935,363
JBrowse link
G Slc27a1 solute carrier family 27 member 1 increases expression
multiple interactions
EXP
ISO
bexarotene results in increased expression of SLC27A1 mRNA
[[Dexamethasone co-treated with INS protein co-treated with 1-Methyl-3-isobutylxanthine] co-treated with bexarotene] results in increased expression of SLC27A1 mRNA
CTD PMID:10777552 NCBI chr16:19,997,823...20,016,193
Ensembl chr16:19,999,112...20,016,190
JBrowse link
G Slc27a2 solute carrier family 27 member 2 decreases expression EXP bexarotene results in decreased expression of SLC27A2 mRNA CTD PMID:16648578 NCBI chr 3:119,014,620...119,052,531
Ensembl chr 3:119,014,620...119,052,531
JBrowse link
G Slc2a2 solute carrier family 2 member 2 increases expression EXP bexarotene results in increased expression of SLC2A2 mRNA CTD PMID:16648578 NCBI chr 2:114,413,427...114,445,418
Ensembl chr 2:114,413,410...114,445,395
JBrowse link
G Slc2a4 solute carrier family 2 member 4 multiple interactions ISO [bexarotene co-treated with rosiglitazone] results in increased expression of SLC2A4 mRNA CTD PMID:10548525 NCBI chr10:56,552,921...56,558,562
Ensembl chr10:56,552,983...56,558,487
JBrowse link
G Slc35b1 solute carrier family 35, member B1 increases expression EXP bexarotene results in increased expression of SLC35B1 mRNA CTD PMID:16648578 NCBI chr10:83,201,532...83,208,605
Ensembl chr10:83,201,311...83,208,605
JBrowse link
G Slc6a6 solute carrier family 6 member 6 increases expression EXP bexarotene results in increased expression of SLC6A6 mRNA CTD PMID:16648578 NCBI chr 4:123,638,619...123,713,469
Ensembl chr 4:123,642,210...123,713,464
JBrowse link
G Slc7a1 solute carrier family 7 member 1 decreases expression ISO bexarotene results in decreased expression of SLC7A1 mRNA CTD PMID:17178900 NCBI chr12:8,032,775...8,108,972
Ensembl chr12:8,032,809...8,108,972
JBrowse link
G Slc7a5 solute carrier family 7 member 5 decreases expression ISO bexarotene results in decreased expression of SLC7A5 mRNA CTD PMID:17178900 NCBI chr19:54,693,959...54,722,563
Ensembl chr19:54,693,959...54,722,563
JBrowse link
G Smad5 SMAD family member 5 increases expression ISO bexarotene results in increased expression of SMAD5 mRNA CTD PMID:17178900 NCBI chr17:8,307,448...8,336,996
Ensembl chr17:8,311,796...8,331,032
JBrowse link
G Sncg synuclein, gamma decreases expression EXP bexarotene results in decreased expression of SNCG mRNA CTD PMID:16648578 NCBI chr16:10,722,110...10,726,648
Ensembl chr16:10,722,106...10,726,707
JBrowse link
G Snd1 staphylococcal nuclease and tudor domain containing 1 increases expression EXP bexarotene results in increased expression of SND1 mRNA CTD PMID:16648578 NCBI chr 4:55,772,377...56,171,669
Ensembl chr 4:55,772,377...56,171,668
JBrowse link
G Snn stannin decreases expression EXP bexarotene results in decreased expression of SNN mRNA CTD PMID:16648578 NCBI chr10:4,635,897...4,644,570
Ensembl chr10:4,635,898...4,644,570
JBrowse link
G Sord sorbitol dehydrogenase decreases expression EXP bexarotene results in decreased expression of SORD mRNA CTD PMID:16648578 NCBI chr 3:114,176,127...114,207,368
Ensembl chr 3:114,176,309...114,207,366
JBrowse link
G Sorl1 sortilin related receptor 1 multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in increased expression of SORL1 mRNA CTD PMID:17630414 NCBI chr 8:46,228,077...46,287,171 JBrowse link
G Sp7 Sp7 transcription factor decreases expression
multiple interactions
ISO bexarotene results in decreased expression of SP7 mRNA
bexarotene inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA]
CTD PMID:25932594 NCBI chr 7:143,957,316...143,967,488
Ensembl chr 7:143,958,858...143,967,484
JBrowse link
G Sparc secreted protein acidic and cysteine rich increases expression ISO bexarotene results in increased expression of SPARC mRNA CTD PMID:17178900 NCBI chr10:40,742,390...40,764,232
Ensembl chr10:40,742,400...40,764,185
JBrowse link
G Spink1 serine peptidase inhibitor, Kazal type 1 multiple interactions
increases expression
EXP [bexarotene co-treated with Tamoxifen] results in increased expression of SPINK1 mRNA
bexarotene results in increased expression of SPINK1 mRNA
CTD PMID:16648578, PMID:17630414 NCBI chr18:38,221,919...38,242,092
Ensembl chr18:38,221,681...38,242,119
JBrowse link
G Spp1 secreted phosphoprotein 1 decreases expression EXP bexarotene results in decreased expression of SPP1 mRNA CTD PMID:16648578 NCBI chr14:6,673,686...6,679,965
Ensembl chr14:6,673,686...6,679,901
JBrowse link
G Spp2 secreted phosphoprotein 2 decreases expression EXP bexarotene results in decreased expression of SPP2 mRNA CTD PMID:16648578 NCBI chr 9:95,501,512...95,509,646
Ensembl chr 9:95,501,778...95,506,365
JBrowse link
G Spt1 salivary protein 1 decreases expression EXP bexarotene results in decreased expression of SPT1 mRNA CTD PMID:16648578 NCBI chr 7:145,325,004...145,338,152
Ensembl chr 7:145,325,004...145,338,152
JBrowse link
G Sqstm1 sequestosome 1 increases expression EXP bexarotene results in increased expression of SQSTM1 mRNA CTD PMID:16648578 NCBI chr10:35,704,728...35,716,316
Ensembl chr10:35,704,730...35,716,294
JBrowse link
G Srd5a1 steroid 5 alpha-reductase 1 decreases expression EXP bexarotene results in decreased expression of SRD5A1 mRNA CTD PMID:16648578 NCBI chr 1:36,320,504...36,354,694
Ensembl chr 1:36,320,461...36,354,756
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 increases expression
multiple interactions
EXP
ISO
bexarotene results in increased expression of SREBF1 mRNA
Bexarotene results in increased expression of SREBF1 mRNA
[Bexarotene co-treated with GW 3965] results in increased expression of SREBF1 mRNA; [Bexarotene co-treated with paxilline] results in increased expression of SREBF1 mRNA; [Bexarotene co-treated with TO-901317] results in increased expression of SREBF1 mRNA; Bexarotene promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SREBF1 mRNA]
CTD PMID:23292798, PMID:25932594, PMID:32123961 NCBI chr10:46,570,996...46,593,021
Ensembl chr10:46,570,996...46,593,009
JBrowse link
G Srsf2 serine and arginine rich splicing factor 2 decreases expression ISO bexarotene results in decreased expression of SRSF2 mRNA CTD PMID:17178900 NCBI chr10:105,792,779...105,795,986
Ensembl chr10:105,792,779...105,795,958
JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 decreases expression EXP bexarotene results in decreased expression of SULT1A1 mRNA CTD PMID:16648578 NCBI chr 1:198,100,586...198,104,106
Ensembl chr 1:198,100,586...198,104,109
JBrowse link
G Sult1b1 sulfotransferase family 1B member 1 decreases expression EXP bexarotene results in decreased expression of SULT1B1 mRNA CTD PMID:16648578 NCBI chr14:22,142,412...22,155,246
Ensembl chr14:22,142,364...22,155,231
JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 decreases expression EXP bexarotene results in decreased expression of SULT2A1 mRNA CTD PMID:16648578 NCBI chr 1:76,558,721...76,614,315
Ensembl chr 1:76,252,329...76,780,230
JBrowse link
G Tacr2 tachykinin receptor 2 increases expression EXP bexarotene results in increased expression of TACR2 mRNA CTD PMID:16648578 NCBI chr20:31,892,515...31,905,153
Ensembl chr20:31,892,515...31,905,153
JBrowse link
G Tecr trans-2,3-enoyl-CoA reductase increases expression EXP bexarotene results in increased expression of TECR mRNA CTD PMID:16648578 NCBI chr19:24,705,478...24,732,024
Ensembl chr19:24,705,481...24,732,024
JBrowse link
G Tex49 testis expressed 49 multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in increased expression of TEX49 mRNA CTD PMID:17630414 NCBI chr 7:140,248,852...140,270,340
Ensembl chr 7:140,248,852...140,270,340
JBrowse link
G Tf transferrin increases expression EXP bexarotene results in increased expression of TF mRNA CTD PMID:16648578 NCBI chr 8:111,694,570...111,721,275
Ensembl chr 8:111,673,547...111,721,333
JBrowse link
G Tg thyroglobulin increases expression EXP bexarotene results in increased expression of TG mRNA CTD PMID:16648578 NCBI chr 7:107,467,260...107,652,897
Ensembl chr 7:107,467,260...107,652,899
JBrowse link
G Tgfb3 transforming growth factor, beta 3 increases expression EXP bexarotene results in increased expression of TGFB3 mRNA CTD PMID:16648578 NCBI chr 6:109,913,757...109,936,217
Ensembl chr 6:109,913,757...109,935,533
JBrowse link
G Tgm1 transglutaminase 1 decreases expression ISO bexarotene results in decreased expression of TGM1 mRNA CTD PMID:8853895 NCBI chr15:34,378,136...34,393,150
Ensembl chr15:34,378,148...34,392,066
JBrowse link
G Tgm2 transglutaminase 2 increases expression
multiple interactions
ISO bexarotene results in increased expression of TGM2 mRNA
diazepinylbenzoic acid inhibits the reaction [bexarotene results in increased expression of TGM2 mRNA]
CTD PMID:17178900, PMID:21622945, PMID:25932594 NCBI chr 3:154,597,165...154,627,257
Ensembl chr 3:154,597,168...154,627,257
JBrowse link
G Thra thyroid hormone receptor alpha multiple interactions ISO bexarotene binds to and results in decreased activity of THRA protein CTD PMID:25752796 NCBI chr10:86,657,285...86,684,935
Ensembl chr10:86,657,285...86,684,933
JBrowse link
G Tm4sf1 transmembrane 4 L six family member 1 increases expression ISO bexarotene results in increased expression of TM4SF1 mRNA CTD PMID:17178900 NCBI chr 2:147,382,866...147,392,062
Ensembl chr 2:147,382,866...147,392,062
JBrowse link
G Tmed2 transmembrane p24 trafficking protein 2 increases expression EXP bexarotene results in increased expression of TMED2 mRNA CTD PMID:16648578 NCBI chr12:37,471,259...37,480,344
Ensembl chr12:37,471,260...37,480,297
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A increases expression EXP bexarotene results in increased expression of TNFRSF1A mRNA CTD PMID:16648578 NCBI chr 4:157,864,905...157,877,634
Ensembl chr 4:157,864,969...157,877,633
JBrowse link
G Tns1 tensin 1 increases expression EXP bexarotene results in increased expression of TNS1 mRNA CTD PMID:16648578 NCBI chr 9:81,190,192...81,401,020
Ensembl chr 9:81,194,119...81,400,987
JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO bexarotene results in increased phosphorylation of and results in increased activity of TP53 protein CTD PMID:19067706 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Tp73 tumor protein p73 increases expression ISO bexarotene results in increased expression of TP73 protein CTD PMID:19067706 NCBI chr 5:171,355,876...171,415,354
Ensembl chr 5:171,355,876...171,415,354
JBrowse link
G Tpm1 tropomyosin 1 increases expression EXP bexarotene results in increased expression of TPM1 mRNA CTD PMID:16648578 NCBI chr 8:72,814,737...72,841,496
Ensembl chr 8:72,814,740...72,842,228
JBrowse link
G Tpm3 tropomyosin 3 increases expression EXP bexarotene results in increased expression of TPM3 mRNA CTD PMID:16648578 NCBI chr 2:189,423,534...189,451,340
Ensembl chr 2:189,423,559...189,451,029
JBrowse link
G Tpm4 tropomyosin 4 increases expression EXP bexarotene results in increased expression of TPM4 mRNA CTD PMID:16648578 NCBI chr16:19,385,810...19,399,851
Ensembl chr16:19,385,736...19,399,903
JBrowse link
G Tsc22d3 TSC22 domain family, member 3 increases expression ISO bexarotene results in increased expression of TSC22D3 mRNA CTD PMID:17178900 NCBI chr  X:111,884,285...111,944,693
Ensembl chr  X:111,884,295...111,887,906
JBrowse link
G Ttr transthyretin decreases expression EXP bexarotene results in decreased expression of TTR mRNA CTD PMID:16648578 NCBI chr18:15,532,963...15,542,180
Ensembl chr18:15,532,963...15,540,177
JBrowse link
G Tuba1a tubulin, alpha 1A increases expression EXP bexarotene results in increased expression of TUBA1A mRNA CTD PMID:16648578 NCBI chr 7:140,637,287...140,640,953
Ensembl chr 7:140,637,287...140,640,953
JBrowse link
G Uap1 UDP-N-acetylglucosamine pyrophosphorylase 1 decreases expression ISO bexarotene results in decreased expression of UAP1 mRNA CTD PMID:17178900 NCBI chr13:88,463,532...88,497,901
Ensembl chr13:88,463,532...88,497,901
JBrowse link
G Ucp2 uncoupling protein 2 multiple interactions ISO bexarotene promotes the reaction [rosiglitazone results in increased expression of UCP2 mRNA] CTD PMID:10548525 NCBI chr 1:165,506,375...165,512,744
Ensembl chr 1:165,506,361...165,512,744
JBrowse link
G Ugt2b UDP glycosyltransferase 2 family, polypeptide B decreases expression EXP bexarotene results in decreased expression of UGT2B mRNA CTD PMID:16648578 Ensembl chr14:22,375,955...22,534,720 JBrowse link
G Vamp8 vesicle-associated membrane protein 8 increases expression ISO bexarotene results in increased expression of VAMP8 mRNA CTD PMID:17178900 NCBI chr 4:100,250,301...100,252,756
Ensembl chr 4:100,250,301...100,252,755
JBrowse link
G Vegfa vascular endothelial growth factor A increases expression EXP bexarotene results in increased expression of VEGFA mRNA CTD PMID:16648578 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
G Xbp1 X-box binding protein 1 decreases expression ISO bexarotene results in decreased expression of XBP1 mRNA CTD PMID:17178900 NCBI chr14:85,753,736...85,758,820
Ensembl chr14:85,753,760...85,758,145
JBrowse link
G Ywhah tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta decreases expression EXP bexarotene results in decreased expression of YWHAH mRNA CTD PMID:16648578 NCBI chr14:83,053,041...83,062,424
Ensembl chr14:83,053,041...83,062,424
JBrowse link
G Zbtb16 zinc finger and BTB domain containing 16 increases expression EXP bexarotene results in increased expression of ZBTB16 mRNA CTD PMID:23292798 NCBI chr 8:52,980,226...53,146,765
Ensembl chr 8:52,985,313...53,146,953
JBrowse link
G Zp3 zona pellucida glycoprotein 3 increases expression EXP bexarotene results in increased expression of ZP3 mRNA CTD PMID:16648578 NCBI chr12:23,735,225...23,752,734
Ensembl chr12:23,735,223...23,742,190
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19787
    role 19734
      application 19393
        pharmaceutical 19275
          drug 19275
            antineoplastic agent 16985
              bexarotene 463
Path 2
Term Annotations click to browse term
  CHEBI ontology 19787
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19672
                    p-block element atom 19672
                      carbon group element atom 19574
                        carbon atom 19563
                          organic molecular entity 19563
                            organic group 18495
                              organic divalent group 18488
                                organodiyl group 18488
                                  carbonyl group 18391
                                    carbonyl compound 18391
                                      carboxylic acid 18061
                                        aromatic carboxylic acid 10889
                                          benzoic acids 10858
                                            bexarotene 463
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.