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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:bexarotene
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Accession:CHEBI:50859 term browser browse the term
Definition:A retinoid that has formula C24H28O2.
Synonyms:exact_synonym: 4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)vinyl]benzoic acid
 related_synonym: Formula=C24H28O2;   InChI=1S/C24H28O2/c1-15-13-20-21(24(5,6)12-11-23(20,3)4)14-19(15)16(2)17-7-9-18(10-8-17)22(25)26/h7-10,13-14H,2,11-12H2,1,3-6H3,(H,25,26);   InChIKey=NAVMQTYZDKMPEU-UHFFFAOYSA-N;   SMILES=Cc1cc2c(cc1C(=C)c1ccc(cc1)C(O)=O)C(C)(C)CCC2(C)C;   bexaroteno;   bexarotenum;   p-(1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthyl)vinyl)benzoic acid
 xref: CAS:153559-49-0;   DrugBank:DB00307;   Drug_Central:361;   KEGG:D03106
 xref_mesh: MESH:C095105
 xref: Patent:US5466861;   Patent:WO9321146;   Wikipedia:Bexarotene


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bexarotene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A1bg alpha-1-B glycoprotein multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in decreased expression of A1BG mRNA CTD PMID:17630414 NCBI chr 7:92,493,934...92,498,460
Ensembl chr 7:92,494,372...92,498,097
JBrowse link
G Abca1 ATP binding cassette subfamily A member 1 increases expression
increases expression
multiple interactions
ISO bexarotene results in increased expression of ABCA1; bexarotene results in increased expression of ABCA1 mRNA
bexarotene increases expression of abca1 protein in mouse hippocampus
bexarotene increases expression of Abca1 protein in mouse cerebral cortex
diazepinylbenzoic acid inhibits the reaction [bexarotene results in increased expression of ABCA1 mRNA]
[bexarotene co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 protein
CTD PMID:21622945 PMID:25932594 PMID:25217640 PMID:26688581 RGD:21408550, RGD:11056803 NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
JBrowse link
G Abcb11 ATP binding cassette subfamily B member 11 increases expression EXP bexarotene results in increased expression of ABCB11 mRNA CTD PMID:16648578 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
JBrowse link
G Abcd3 ATP binding cassette subfamily D member 3 increases expression EXP bexarotene results in increased expression of ABCD3 mRNA CTD PMID:16648578 PMID:23292798 NCBI chr 2:209,852,087...209,905,763
Ensembl chr 2:209,852,087...209,906,020
JBrowse link
G Acaa1a acetyl-CoA acyltransferase 1A increases expression
multiple interactions
EXP bexarotene results in increased expression of ACAA1 mRNA; bexarotene results in increased expression of ACAA1A mRNA
[Tamoxifen co-treated with bexarotene] results in increased expression of ACAA1 mRNA
CTD PMID:16648578 PMID:17630414 NCBI chr 8:119,079,401...119,088,624
Ensembl chr 8:119,079,775...119,088,624
JBrowse link
G Acaca acetyl-CoA carboxylase alpha increases expression EXP bexarotene results in increased expression of ACACA mRNA CTD PMID:23292798 NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457
JBrowse link
G Acadm acyl-CoA dehydrogenase medium chain increases expression EXP bexarotene results in increased expression of ACADM mRNA CTD PMID:23292798 NCBI chr 2:242,858,865...242,883,036
Ensembl chr 2:242,858,865...242,883,147
JBrowse link
G Acat1 acetyl-CoA acetyltransferase 1 increases expression
multiple interactions
EXP bexarotene results in increased expression of ACAT1 mRNA
[Tamoxifen co-treated with bexarotene] results in increased expression of ACAT1 mRNA
CTD PMID:16648578 PMID:17630414 NCBI chr 8:53,979,813...54,008,861
Ensembl chr 8:53,979,813...54,008,855
JBrowse link
G Ache acetylcholinesterase decreases expression EXP bexarotene results in decreased expression of ACHE mRNA CTD PMID:16648578 NCBI chr12:19,407,359...19,413,713
Ensembl chr12:19,407,360...19,413,651
JBrowse link
G Acot1 acyl-CoA thioesterase 1 increases expression
multiple interactions
EXP Bexarotene results in increased expression of ACOT1 mRNA
[Tamoxifen co-treated with Bexarotene] results in increased expression of ACOT1 mRNA
CTD PMID:16648578 PMID:17630414 NCBI chr 6:103,636,173...103,644,167
Ensembl chr 6:103,636,041...103,644,163
JBrowse link
G Acot2 acyl-CoA thioesterase 2 increases expression EXP bexarotene results in increased expression of ACOT2 mRNA CTD PMID:16648578 NCBI chr 6:103,611,744...103,619,404
Ensembl chr 6:103,611,544...103,619,245
JBrowse link
G Acox1 acyl-CoA oxidase 1 increases expression EXP bexarotene results in increased expression of ACOX1 mRNA CTD PMID:16648578 PMID:23292798 NCBI chr10:101,406,197...101,431,242
Ensembl chr10:101,406,197...101,431,232
JBrowse link
G Acsl1 acyl-CoA synthetase long-chain family member 1 increases expression EXP bexarotene results in increased expression of ACSL1 mRNA CTD PMID:23292798 NCBI chr16:45,755,246...45,821,541
Ensembl chr16:45,755,254...45,821,541
JBrowse link
G Acsl5 acyl-CoA synthetase long-chain family member 5 increases expression EXP bexarotene results in increased expression of ACSL5 mRNA CTD PMID:23292798 NCBI chr 1:254,289,513...254,336,608
Ensembl chr 1:254,292,521...254,336,607
JBrowse link
G Acsm3 acyl-CoA synthetase medium-chain family member 3 multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in increased expression of SAH mRNA CTD PMID:17630414 NCBI chr 1:174,133,260...174,159,966
Ensembl chr 1:174,133,288...174,160,184
JBrowse link
G Acta2 actin alpha 2, smooth muscle increases expression EXP bexarotene results in increased expression of ACTA2 mRNA CTD PMID:16648578 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
JBrowse link
G Actc1 actin, alpha, cardiac muscle 1 increases expression EXP bexarotene results in increased expression of ACTC1 mRNA CTD PMID:16648578 NCBI chr 3:100,811,987...100,817,523
Ensembl chr 3:100,811,987...100,817,523
JBrowse link
G Actg1 actin, gamma 1 increases expression EXP bexarotene results in increased expression of ACTG1 mRNA CTD PMID:16648578 NCBI chr10:105,619,738...105,622,587
Ensembl chr10:105,619,737...105,624,232
JBrowse link
G Acvr2b activin A receptor type 2B increases expression EXP bexarotene results in increased expression of ACVR2B mRNA CTD PMID:16648578 NCBI chr 8:119,138,901...119,178,477
Ensembl chr 8:119,138,812...119,170,458
JBrowse link
G Adcy6 adenylate cyclase 6 decreases expression EXP bexarotene results in decreased expression of ADCY6 mRNA CTD PMID:16648578 NCBI chr 7:129,742,827...129,763,922
Ensembl chr 7:129,742,838...129,763,754
JBrowse link
G Add3 adducin 3 increases expression ISO bexarotene results in increased expression of ADD3 mRNA CTD PMID:17178900 NCBI chr 1:252,147,341...252,255,126
Ensembl chr 1:252,147,386...252,255,124
JBrowse link
G Adh4 alcohol dehydrogenase 4 (class II), pi polypeptide increases expression EXP bexarotene results in increased expression of ADH4 mRNA CTD PMID:17630414 NCBI chr 2:226,948,717...226,966,747 JBrowse link
G Adig adipogenin multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in increased expression of ADIG mRNA CTD PMID:17630414 NCBI chr 3:147,155,021...147,160,413 JBrowse link
G Adra1b adrenoceptor alpha 1B decreases expression EXP bexarotene results in decreased expression of ADRA1B mRNA CTD PMID:16648578 NCBI chr10:28,255,025...28,373,418
Ensembl chr10:28,255,025...28,312,919
JBrowse link
G Adrb2 adrenoceptor beta 2 decreases expression ISO bexarotene results in decreased expression of ADRB2 mRNA CTD PMID:17178900 NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512
JBrowse link
G Agxt alanine--glyoxylate and serine--pyruvate aminotransferase increases expression EXP bexarotene results in increased expression of AGXT mRNA CTD PMID:16648578 NCBI chr 9:93,675,384...93,685,337
Ensembl chr 9:93,675,384...93,685,336
JBrowse link
G Ahsg alpha-2-HS-glycoprotein decreases expression EXP bexarotene results in decreased expression of AHSG mRNA CTD PMID:16648578 NCBI chr11:78,117,903...78,145,956 JBrowse link
G Akap12 A-kinase anchoring protein 12 increases expression EXP bexarotene results in increased expression of AKAP12 mRNA CTD PMID:16648578 NCBI chr 1:40,730,123...40,819,863
Ensembl chr 1:40,730,123...40,819,886
JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 increases expression ISO bexarotene results in increased expression of AKR1C3 mRNA CTD PMID:17178900 NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873
JBrowse link
G Aldh3a2 aldehyde dehydrogenase 3 family, member A2 decreases expression EXP bexarotene results in decreased expression of ALDH3A2 mRNA CTD PMID:16648578 NCBI chr10:45,928,313...45,949,366
Ensembl chr10:45,908,524...45,949,281
JBrowse link
G Aldoa aldolase, fructose-bisphosphate A increases expression EXP Bexarotene results in increased expression of ALDOA mRNA CTD PMID:16648578 NCBI chr 1:181,402,275...181,407,476
Ensembl chr 1:181,402,275...181,406,182
JBrowse link
G Aldob aldolase, fructose-bisphosphate B decreases expression EXP bexarotene results in decreased expression of ALDOB mRNA CTD PMID:16648578 NCBI chr 5:63,889,045...63,902,086
Ensembl chr 5:63,889,046...63,902,116
JBrowse link
G Aldoc aldolase, fructose-bisphosphate C increases expression EXP bexarotene results in increased expression of ALDOC mRNA CTD PMID:16648578 NCBI chr10:63,217,477...63,221,066
Ensembl chr10:63,217,451...63,221,066
JBrowse link
G Alpl alkaline phosphatase, biomineralization associated increases expression EXP bexarotene results in increased expression of ALPL mRNA CTD PMID:16648578 NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446
JBrowse link
G Amotl2 angiomotin like 2 decreases expression ISO bexarotene results in decreased expression of AMOTL2 mRNA CTD PMID:17178900 NCBI chr 8:103,303,368...103,319,161
Ensembl chr 8:103,302,992...103,318,910
JBrowse link
G Angptl4 angiopoietin-like 4 increases expression ISO bexarotene results in increased expression of ANGPTL4 mRNA CTD PMID:21622945 NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519
JBrowse link
G Ank3 ankyrin 3 decreases expression EXP bexarotene results in decreased expression of ANK3 mRNA CTD PMID:16648578 NCBI chr20:18,602,267...19,225,831
Ensembl chr20:18,602,786...19,086,300
JBrowse link
G Anxa3 annexin A3 multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in decreased expression of ANXA3 mRNA CTD PMID:17630414 NCBI chr14:12,727,708...12,781,717
Ensembl chr14:12,719,795...12,781,617
JBrowse link
G Aplp2 amyloid beta precursor like protein 2 increases expression EXP bexarotene results in increased expression of APLP2 mRNA CTD PMID:16648578 NCBI chr 8:29,599,230...29,662,311
Ensembl chr 8:29,599,230...29,661,855
JBrowse link
G Apoa2 apolipoprotein A2 multiple interactions
increases expression
decreases expression
ISO
EXP
RXRA promotes the reaction [bexarotene results in increased expression of APOA2 mRNA]
bexarotene results in decreased expression of APOA2 mRNA
CTD PMID:8668150 PMID:16648578 NCBI chr13:83,644,460...83,646,358
Ensembl chr13:83,644,470...83,646,355
JBrowse link
G Apob apolipoprotein B decreases expression EXP bexarotene results in decreased expression of APOB mRNA CTD PMID:16648578 NCBI chr 6:30,844,386...30,883,983
Ensembl chr 6:30,844,368...30,892,497
JBrowse link
G Apoc1 apolipoprotein C1 decreases expression EXP bexarotene results in decreased expression of APOC1 mRNA CTD PMID:16648578 NCBI chr 1:79,347,057...79,350,340
Ensembl chr 1:79,346,136...79,350,375
JBrowse link
G Apoc3 apolipoprotein C3 decreases expression EXP bexarotene results in decreased expression of APOC3 mRNA CTD PMID:16648578 NCBI chr 8:46,531,478...46,533,658
Ensembl chr 8:46,531,478...46,533,583
JBrowse link
G Apod apolipoprotein D increases expression ISO bexarotene results in increased expression of APOD mRNA CTD PMID:17849452 NCBI chr11:69,431,261...69,452,306
Ensembl chr11:69,431,260...69,452,305
JBrowse link
G App amyloid beta precursor protein increases expression EXP bexarotene results in increased expression of APP mRNA CTD PMID:16648578 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Aqp7 aquaporin 7 multiple interactions
decreases expression
EXP [bexarotene co-treated with Tamoxifen] results in increased expression of AQP7 mRNA
bexarotene results in decreased expression of AQP7 mRNA
CTD PMID:16648578 PMID:17630414 NCBI chr 5:56,171,649...56,186,642
Ensembl chr 5:56,172,519...56,186,642
JBrowse link
G Ar androgen receptor multiple interactions
increases expression
ISO
EXP
bexarotene binds to and results in decreased activity of AR protein
bexarotene results in increased expression of AR mRNA
CTD PMID:16648578 PMID:25752796 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Arf1 ADP-ribosylation factor 1 increases expression EXP bexarotene results in increased expression of ARF1 mRNA CTD PMID:16648578 NCBI chr10:43,997,983...44,014,543
Ensembl chr10:43,997,986...44,014,434
JBrowse link
G Arg1 arginase 1 decreases expression EXP bexarotene results in decreased expression of ARG1 mRNA CTD PMID:16648578 NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422
JBrowse link
G Arl6ip5 ADP-ribosylation factor like GTPase 6 interacting protein 5 increases expression ISO bexarotene results in increased expression of ARL6IP5 mRNA CTD PMID:17178900 NCBI chr 4:129,810,650...129,838,628
Ensembl chr 4:129,810,645...129,838,608
JBrowse link
G Arpc1b actin related protein 2/3 complex, subunit 1B increases expression EXP bexarotene results in increased expression of ARPC1B mRNA CTD PMID:16648578 NCBI chr12:9,482,176...9,495,772
Ensembl chr12:9,480,831...9,495,747
JBrowse link
G Ascl1 achaete-scute family bHLH transcription factor 1 multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in decreased expression of ASCL1 mRNA CTD PMID:17630414 NCBI chr 7:21,904,153...21,906,003
Ensembl chr 7:21,903,126...21,905,993
JBrowse link
G Asgr1 asialoglycoprotein receptor 1 increases expression EXP bexarotene results in increased expression of ASGR1 mRNA CTD PMID:16648578 NCBI chr10:54,775,727...54,779,642
Ensembl chr10:54,776,024...54,779,631
JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) decreases expression ISO bexarotene results in decreased expression of ASNS mRNA CTD PMID:17178900 NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423
JBrowse link
G Atm ATM serine/threonine kinase increases activity ISO bexarotene results in increased activity of ATM protein CTD PMID:19067706 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
JBrowse link
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 increases expression EXP bexarotene results in increased expression of ATP1A1 mRNA CTD PMID:16648578 NCBI chr 2:189,020,722...189,048,826
Ensembl chr 2:189,020,722...189,048,837
JBrowse link
G Atp1b1 ATPase Na+/K+ transporting subunit beta 1 decreases expression EXP bexarotene results in decreased expression of ATP1B1 mRNA CTD PMID:16648578 NCBI chr13:76,786,580...76,807,096
Ensembl chr13:76,786,578...76,807,459
JBrowse link
G Atp4a ATPase H+/K+ transporting subunit alpha increases expression EXP bexarotene results in increased expression of ATP4A mRNA CTD PMID:16648578 NCBI chr 1:85,961,607...85,974,972
Ensembl chr 1:85,961,708...85,974,844
JBrowse link
G Atp5f1d ATP synthase F1 subunit delta increases expression EXP bexarotene results in increased expression of ATP5F1D mRNA CTD PMID:16648578 NCBI chr 7:9,560,604...9,565,919
Ensembl chr 7:9,560,608...9,565,929
JBrowse link
G Atp6v0c ATPase H+ transporting V0 subunit C increases expression EXP bexarotene results in increased expression of ATP6V0C mRNA CTD PMID:16648578 NCBI chr10:13,196,204...13,202,580
Ensembl chr10:13,196,204...13,201,500
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO bexarotene results in increased expression of and results in increased activity of BAX protein CTD PMID:19067706 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bbs2 Bardet-Biedl syndrome 2 multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in increased expression of BBS2 mRNA CTD PMID:17630414 NCBI chr19:10,909,653...10,944,998
Ensembl chr19:10,909,619...10,944,993
JBrowse link
G Bglap bone gamma-carboxyglutamate protein multiple interactions ISO bexarotene inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA] CTD PMID:25932594 NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495
JBrowse link
G Bhlhe41 basic helix-loop-helix family, member e41 decreases expression EXP bexarotene results in decreased expression of BHLHE41 mRNA CTD PMID:16648578 NCBI chr 4:178,833,085...178,838,685
Ensembl chr 4:178,834,271...178,838,468
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases expression ISO bexarotene results in decreased expression of BIRC5 mRNA
bexarotene results in decreased expression of BIRC5 protein
CTD PMID:17849452 PMID:19067706 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
JBrowse link
G Bmp2 bone morphogenetic protein 2 multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in decreased expression of BMP2 mRNA CTD PMID:17630414 NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397
JBrowse link
G Bnip2 BCL2 interacting protein 2 decreases expression ISO bexarotene results in decreased expression of BNIP2 mRNA CTD PMID:17178900 NCBI chr 8:70,640,436...70,661,782
Ensembl chr 8:70,640,445...70,675,590
JBrowse link
G Btg2 BTG anti-proliferation factor 2 decreases expression EXP bexarotene results in decreased expression of BTG2 mRNA CTD PMID:16648578 NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628
JBrowse link
G C1qb complement C1q B chain multiple interactions
increases expression
EXP [bexarotene co-treated with Tamoxifen] results in decreased expression of C1QB mRNA
bexarotene results in increased expression of C1QB mRNA
CTD PMID:16648578 PMID:17630414 NCBI chr 5:149,118,843...149,124,394
Ensembl chr 5:149,118,846...149,124,407
JBrowse link
G C3 complement C3 decreases expression EXP bexarotene results in decreased expression of C3 mRNA CTD PMID:16648578 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429
JBrowse link
G C4bpa complement component 4 binding protein, alpha decreases expression EXP bexarotene results in decreased expression of C4BPA mRNA CTD PMID:16648578 NCBI chr13:42,075,715...42,111,205
Ensembl chr13:42,075,717...42,111,205
JBrowse link
G Cacna2d3 calcium voltage-gated channel auxiliary subunit alpha2delta 3 multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in increased expression of CACNA2D3 mRNA CTD PMID:17630414 NCBI chr16:4,098,439...4,912,498
Ensembl chr16:4,098,445...4,912,351
JBrowse link
G Calr calreticulin increases expression EXP bexarotene results in increased expression of CALR mRNA CTD PMID:16648578 NCBI chr19:23,308,525...23,313,420
Ensembl chr19:23,308,351...23,313,414
JBrowse link
G Camk2g calcium/calmodulin-dependent protein kinase II gamma increases expression EXP bexarotene results in increased expression of CAMK2G mRNA CTD PMID:16648578 NCBI chr15:3,504,017...3,563,050
Ensembl chr15:3,504,085...3,563,050
JBrowse link
G Canx calnexin increases expression EXP bexarotene results in increased expression of CANX mRNA CTD PMID:16648578 NCBI chr10:34,623,865...34,656,866
Ensembl chr10:34,625,191...34,656,821
JBrowse link
G Casp3 caspase 3 decreases expression ISO bexarotene results in decreased expression of CASP3 mRNA CTD PMID:17849452 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp6 caspase 6 decreases expression EXP bexarotene results in decreased expression of CASP6 mRNA CTD PMID:16648578 NCBI chr 2:218,466,063...218,478,503
Ensembl chr 2:218,466,076...218,478,502
JBrowse link
G Cbr1 carbonyl reductase 1 increases expression EXP bexarotene results in increased expression of CBR1 mRNA CTD PMID:16648578 NCBI chr11:32,860,618...32,862,981
Ensembl chr11:32,908,950...32,911,393
JBrowse link
G Ccl11 C-C motif chemokine ligand 11 decreases expression EXP bexarotene results in decreased expression of CCL11 mRNA CTD PMID:16648578 NCBI chr10:67,028,328...67,032,929
Ensembl chr10:67,028,328...67,032,926
JBrowse link
G Ccn1 cellular communication network factor 1 decreases expression ISO Bexarotene results in decreased expression of CCN1 mRNA CTD PMID:17178900 NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484
JBrowse link
G Ccnb1 cyclin B1 decreases expression ISO bexarotene results in decreased expression of CCNB1 protein CTD PMID:19067706 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
JBrowse link
G Ccnb2 cyclin B2 decreases expression ISO bexarotene results in decreased expression of CCNB2 mRNA CTD PMID:17849452 NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874
JBrowse link
G Ccnd1 cyclin D1 increases expression
decreases expression
EXP
ISO
bexarotene results in increased expression of CCND1 mRNA
bexarotene results in decreased expression of CCND1 mRNA
CTD PMID:16648578 PMID:17178900 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccne1 cyclin E1 decreases expression ISO bexarotene results in decreased expression of CCNE1 mRNA CTD PMID:17849452 NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101
JBrowse link
G Cd14 CD14 molecule increases expression EXP bexarotene results in increased expression of CD14 mRNA CTD PMID:16648578 NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261
JBrowse link
G Cd36 CD36 molecule increases expression EXP bexarotene results in increased expression of CD36 mRNA CTD PMID:16648578 PMID:23292798 NCBI chr 4:17,317,343...17,410,084 JBrowse link
G Cd37 CD37 molecule increases expression EXP bexarotene results in increased expression of CD37 mRNA CTD PMID:16648578 NCBI chr 1:95,719,171...95,724,662
Ensembl chr 1:95,719,190...95,724,648
JBrowse link
G Cd48 Cd48 molecule multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in decreased expression of CD48 mRNA CTD PMID:17630414 NCBI chr13:84,184,884...84,209,144
Ensembl chr13:84,185,532...84,209,142
JBrowse link
G Cd5l Cd5 molecule-like multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in decreased expression of CD5L mRNA CTD PMID:17630414 NCBI chr 2:172,791,007...172,802,018 JBrowse link
G Cd68 Cd68 molecule multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in decreased expression of CD68 mRNA CTD PMID:17630414 NCBI chr10:54,381,814...54,383,693
Ensembl chr10:54,381,815...54,383,697
JBrowse link
G Cd74 CD74 molecule increases expression EXP bexarotene results in increased expression of CD74 mRNA CTD PMID:16648578 NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003
JBrowse link
G Cdc37 cell division cycle 37, HSP90 cochaperone increases expression EXP bexarotene results in increased expression of CDC37 mRNA CTD PMID:16648578 NCBI chr 8:19,677,400...19,690,761
Ensembl chr 8:19,671,938...19,690,809
JBrowse link
G Cdk1 cyclin-dependent kinase 1 decreases expression ISO bexarotene results in decreased expression of CDK1 protein CTD PMID:19067706 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO bexarotene results in increased expression of CDKN1A protein CTD PMID:19067706 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdo1 cysteine dioxygenase type 1 decreases expression EXP bexarotene results in decreased expression of CDO1 mRNA CTD PMID:16648578 NCBI chr18:39,432,473...39,447,253
Ensembl chr18:39,432,474...39,447,296
JBrowse link
G Cebpg CCAAT/enhancer binding protein gamma decreases expression ISO bexarotene results in decreased expression of CEBPG mRNA CTD PMID:17178900 NCBI chr 1:87,683,060...87,692,772
Ensembl chr 1:87,684,019...87,694,569
JBrowse link
G Ces2h carboxylesterase 2H increases expression
multiple interactions
EXP bexarotene results in increased expression of CES2 mRNA
[Tamoxifen co-treated with bexarotene] results in increased expression of CES2 mRNA
CTD PMID:16648578 PMID:17630414 NCBI chr19:32,974,242...32,988,842
Ensembl chr19:32,974,242...32,988,830
JBrowse link
G Cfd complement factor D multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in decreased expression of CFD mRNA CTD PMID:17630414 NCBI chr 7:9,813,148...9,814,871
Ensembl chr 7:9,813,150...9,815,053
JBrowse link
G Chrna2 cholinergic receptor nicotinic alpha 2 subunit increases expression EXP bexarotene results in increased expression of CHRNA2 mRNA CTD PMID:16648578 PMID:17630414 NCBI chr15:40,342,317...40,358,601
Ensembl chr15:40,342,317...40,358,601
JBrowse link
G Ciao1 cytosolic iron-sulfur assembly component 1 decreases expression EXP bexarotene results in decreased expression of CIAO1 mRNA CTD PMID:16648578 NCBI chr 3:114,458,671...114,465,928
Ensembl chr 3:114,458,655...114,467,009
JBrowse link
G Ckb creatine kinase B increases expression EXP bexarotene results in increased expression of CKB mRNA CTD PMID:16648578 NCBI chr 6:130,729,420...130,732,301
Ensembl chr 6:130,729,423...130,732,315
JBrowse link
G Cldn3 claudin 3 increases expression EXP bexarotene results in increased expression of CLDN3 mRNA CTD PMID:16648578 NCBI chr12:21,708,538...21,710,010
Ensembl chr12:21,708,398...21,711,001
JBrowse link
G Cldn7 claudin 7 increases expression EXP bexarotene results in increased expression of CLDN7 mRNA CTD PMID:16648578 NCBI chr10:54,689,684...54,692,177
Ensembl chr10:54,689,987...54,692,171
JBrowse link
G Col12a1 collagen type XII alpha 1 chain decreases expression EXP bexarotene results in decreased expression of COL12A1 mRNA CTD PMID:16648578 NCBI chr 8:80,547,592...80,665,665
Ensembl chr 8:80,547,593...80,665,686
JBrowse link
G Colq collagen like tail subunit of asymmetric acetylcholinesterase increases expression EXP bexarotene results in increased expression of COLQ mRNA CTD PMID:16648578 NCBI chr16:6,731,850...6,824,973
Ensembl chr16:6,731,858...6,787,107
JBrowse link
G Comt catechol-O-methyltransferase decreases expression
increases expression
EXP bexarotene results in decreased expression of COMT mRNA
bexarotene results in increased expression of COMT mRNA
CTD PMID:16648578 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642
JBrowse link
G Coro1b coronin 1B increases expression EXP bexarotene results in increased expression of CORO1B mRNA CTD PMID:16648578 NCBI chr 1:201,442,977...201,448,416
Ensembl chr 1:201,443,014...201,448,416
JBrowse link
G Cpa1 carboxypeptidase A1 multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in decreased expression of CPA1 mRNA CTD PMID:17630414 NCBI chr 4:59,257,417...59,263,544
Ensembl chr 4:59,257,417...59,263,544
JBrowse link
G Cps1 carbamoyl-phosphate synthase 1 decreases expression EXP bexarotene results in decreased expression of CPS1 mRNA CTD PMID:16648578 NCBI chr 9:68,614,153...68,737,037
Ensembl chr 9:68,614,153...68,737,033
JBrowse link
G Cpt1b carnitine palmitoyltransferase 1B multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in increased expression of CPT1B mRNA CTD PMID:17630414 NCBI chr 7:120,491,354...120,500,833
Ensembl chr 7:120,491,354...120,500,404
JBrowse link
G Cpt2 carnitine palmitoyltransferase 2 increases expression EXP bexarotene results in increased expression of CPT2 mRNA CTD PMID:16648578 NCBI chr 5:122,664,677...122,682,126
Ensembl chr 5:122,664,677...122,682,095
JBrowse link
G Crot carnitine O-octanoyltransferase increases expression EXP bexarotene results in increased expression of CROT mRNA CTD PMID:16648578 NCBI chr 4:25,068,270...25,133,111
Ensembl chr 4:25,080,587...25,133,109
JBrowse link
G Csf1r colony stimulating factor 1 receptor multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in decreased expression of CSF1R mRNA CTD PMID:17630414 NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415
JBrowse link
G Cspg5 chondroitin sulfate proteoglycan 5 increases expression EXP bexarotene results in increased expression of CSPG5 mRNA CTD PMID:16648578 NCBI chr 8:110,220,653...110,234,750
Ensembl chr 8:110,220,653...110,234,758
JBrowse link
G Csrp2 cysteine and glycine-rich protein 2 decreases expression EXP bexarotene results in decreased expression of CSRP2 mRNA CTD PMID:16648578 NCBI chr 7:46,349,109...46,367,743
Ensembl chr 7:46,348,686...46,367,745
JBrowse link
G Cth cystathionine gamma-lyase decreases expression ISO bexarotene results in decreased expression of CTH mRNA CTD PMID:17178900 NCBI chr 2:246,975,888...247,002,234
Ensembl chr 2:246,975,894...247,002,234
JBrowse link
G Ctrc chymotrypsin C increases expression EXP bexarotene results in increased expression of CTRC mRNA CTD PMID:16648578 NCBI chr 5:154,147,314...154,156,540
Ensembl chr 5:154,147,316...154,156,528
JBrowse link
G Ctsh cathepsin H increases expression ISO bexarotene results in increased expression of CTSH mRNA CTD PMID:17178900 NCBI chr 8:90,608,941...90,627,824
Ensembl chr 8:90,608,941...90,627,824
JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in decreased expression of CXCL1 mRNA CTD PMID:17630414 NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215
JBrowse link
G Cxcl14 C-X-C motif chemokine ligand 14 decreases expression EXP bexarotene results in decreased expression of CXCL14 mRNA CTD PMID:16648578 NCBI chr17:8,317,933...8,325,956
Ensembl chr17:8,317,933...8,324,839
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 decreases expression EXP bexarotene results in decreased expression of CXCL3 mRNA CTD PMID:16648578 NCBI chr14:17,270,146...17,289,458
Ensembl chr14:17,270,146...17,289,511
JBrowse link
G Cyb5a cytochrome b5 type A decreases expression EXP bexarotene results in decreased expression of CYB5A mRNA CTD PMID:16648578 NCBI chr18:78,213,067...78,245,677
Ensembl chr18:78,202,342...78,258,535
Ensembl chr18:78,202,342...78,258,535
JBrowse link
G Cycs cytochrome c, somatic decreases expression ISO bexarotene results in decreased expression of CYCS mRNA CTD PMID:17178900 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in increased expression of CYP17A1 mRNA CTD PMID:17630414 NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases expression EXP bexarotene results in decreased expression of CYP1A2 mRNA CTD PMID:16648578 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases expression EXP bexarotene results in increased expression of CYP1B1 mRNA CTD PMID:16648578 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 increases expression
multiple interactions
ISO
EXP
bexarotene results in increased expression of CYP26A1 mRNA
[bexarotene co-treated with Tamoxifen] results in increased expression of CYP26A1 mRNA
CTD PMID:17178900 PMID:17630414 NCBI chr 1:235,471,368...235,475,204
Ensembl chr 1:235,471,298...235,475,204
JBrowse link
G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 increases expression ISO bexarotene results in increased expression of CYP26B1 mRNA CTD PMID:17849452 NCBI chr 4:117,041,808...117,058,628
Ensembl chr 4:117,041,808...117,058,628
JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 increases expression EXP bexarotene results in increased expression of CYP27A1 mRNA CTD PMID:16648578 NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551
JBrowse link
G Cyp2a1 cytochrome P450, family 2, subfamily a, polypeptide 1 multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in increased expression of CYP2A1 mRNA CTD PMID:17630414 NCBI chr 1:82,231,611...82,244,887
Ensembl chr 1:82,231,611...82,244,887
JBrowse link
G Cyp2a2 cytochrome P450, family 2, subfamily a, polypeptide 2 decreases expression EXP bexarotene results in decreased expression of CYP2A2 mRNA CTD PMID:16648578 NCBI chr 1:82,263,833...82,289,487
Ensembl chr 1:82,263,833...82,289,487
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 increases expression EXP bexarotene results in increased expression of CYP2B1 mRNA CTD PMID:23292798 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
JBrowse link
G Cyp2b15 cytochrome P450, family 2, subfamily b, polypeptide 15 increases expression EXP bexarotene results in increased expression of CYP2B15 mRNA CTD PMID:16648578 NCBI chr 1:82,094,188...82,106,492
Ensembl chr 1:82,094,180...82,106,492
JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 increases expression EXP bexarotene results in increased expression of CYP2B2 mRNA CTD PMID:16648578 NCBI chr 1:81,594,534...81,608,567
Ensembl chr 1:81,594,555...81,608,566
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases expression
multiple interactions
ISO Bexarotene results in increased expression of CYP2B6 mRNA
RXRA protein affects the reaction [Bexarotene results in increased expression of CYP2B6 mRNA]
CTD PMID:31312845 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
JBrowse link
G Cyp2c12 cytochrome P450, family 2, subfamily c, polypeptide 12 decreases expression EXP bexarotene results in decreased expression of CYP2C12 mRNA CTD PMID:16648578 NCBI chr 1:238,699,859...238,757,011
Ensembl chr 1:238,699,854...238,757,019
JBrowse link
G Cyp2c7 cytochrome P450, family 2, subfamily c, polypeptide 7 decreases expression EXP bexarotene results in decreased expression of CYP2C7 mRNA CTD PMID:16648578 NCBI chr 1:237,332,641...237,388,714
Ensembl chr 1:237,332,659...237,388,709
JBrowse link
G Cyp2d3 cytochrome P450, family 2, subfamily d, polypeptide 3 increases expression EXP bexarotene results in increased expression of CYP2D3 mRNA CTD PMID:16648578 NCBI chr 7:113,917,711...113,922,068 JBrowse link
G Cyp2t1 cytochrome P450, family 2, subfamily t, polypeptide 1 decreases expression
multiple interactions
EXP bexarotene results in decreased expression of CYP2T1 mRNA
[Tamoxifen co-treated with bexarotene] results in decreased expression of CYP2T1 mRNA
CTD PMID:17630414 NCBI chr 1:82,446,321...82,451,564
Ensembl chr 1:82,446,921...82,451,563
JBrowse link
G Cyp3a18 cytochrome P450, family 3, subfamily a, polypeptide 18 decreases expression EXP bexarotene results in decreased expression of CYP3A18 mRNA CTD PMID:16648578 NCBI chr12:8,880,528...8,930,382
Ensembl chr12:8,880,528...8,930,381
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 decreases expression
increases expression
EXP Bexarotene results in decreased expression of CYP3A23-3A1 mRNA
Bexarotene results in increased expression of CYP3A23-3A1 mRNA
CTD PMID:16648578 PMID:23292798 NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030
JBrowse link
G Cyp4a1 cytochrome P450, family 4, subfamily a, polypeptide 1 increases expression EXP bexarotene results in increased expression of CYP4A22 mRNA CTD PMID:16648578 NCBI chr 5:129,123,323...129,137,464
Ensembl chr 5:129,123,336...129,137,464
JBrowse link
G Cyp4f1 cytochrome P450, family 4, subfamily f, polypeptide 1 decreases expression EXP bexarotene results in decreased expression of CYP4F1 mRNA CTD PMID:16648578 NCBI chr 7:12,010,850...12,022,497
Ensembl chr 7:12,010,852...12,022,046
JBrowse link
G Cyp8b1 cytochrome P450 family 8 subfamily B member 1 multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in decreased expression of CYP8B1 mRNA CTD PMID:17630414 NCBI chr 8:121,578,123...121,580,093
Ensembl chr 8:121,557,062...121,580,166
JBrowse link
G Dact2 dishevelled-binding antagonist of beta-catenin 2 increases expression EXP bexarotene results in increased expression of DACT2 mRNA CTD PMID:17630414 NCBI chr 1:55,181,023...55,191,026
Ensembl chr 1:55,181,024...55,191,096
JBrowse link
G Dapk3 death-associated protein kinase 3 decreases expression EXP bexarotene results in decreased expression of DAPK3 mRNA CTD PMID:16648578 NCBI chr 7:8,524,182...8,532,552
Ensembl chr 7:8,524,183...8,532,558
JBrowse link
G Dbp D-box binding PAR bZIP transcription factor decreases expression EXP bexarotene results in decreased expression of DBP mRNA CTD PMID:16648578 NCBI chr 1:96,175,796...96,180,745
Ensembl chr 1:96,175,440...96,180,745
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 decreases expression EXP bexarotene results in decreased expression of DDIT3 mRNA CTD PMID:16648578 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 increases expression ISO bexarotene results in increased expression of DDIT4 mRNA CTD PMID:17178900 NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105
JBrowse link
G Decr2 2,4-dienoyl-CoA reductase 2 increases expression EXP bexarotene results in increased expression of DECR2 mRNA CTD PMID:16648578 NCBI chr10:15,104,907...15,113,281 JBrowse link
G Depp1 DEPP1, autophagy regulator increases expression ISO bexarotene results in increased expression of DEPP1 mRNA CTD PMID:17178900 NCBI chr 4:149,910,794...149,913,013
Ensembl chr 4:149,910,779...149,914,542
JBrowse link
G Dhcr7 7-dehydrocholesterol reductase increases expression EXP bexarotene results in increased expression of DHCR7 mRNA CTD PMID:16648578 NCBI chr 1:199,015,081...199,031,055
Ensembl chr 1:199,015,081...199,031,055
JBrowse link
G Dhrs3 dehydrogenase/reductase 3 increases expression ISO bexarotene results in increased expression of DHRS3 mRNA CTD PMID:17178900 NCBI chr 5:156,747,939...156,782,420
Ensembl chr 5:156,747,962...156,782,417
JBrowse link
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 increases expression ISO bexarotene results in increased expression of DKK1 mRNA CTD PMID:17178900 NCBI chr 1:228,381,521...228,385,202
Ensembl chr 1:228,381,521...228,385,202
JBrowse link
G Dlat dihydrolipoamide S-acetyltransferase increases expression EXP bexarotene results in increased expression of DLAT mRNA CTD PMID:16648578 NCBI chr 8:50,979,151...51,004,435
Ensembl chr 8:50,978,051...51,004,479
JBrowse link
G Dmp1 dentin matrix acidic phosphoprotein 1 multiple interactions ISO bexarotene inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of DMP1 mRNA] CTD PMID:25932594 NCBI chr14:5,528,441...5,542,078
Ensembl chr14:5,528,431...5,539,323
JBrowse link
G Dnaja1 DnaJ heat shock protein family (Hsp40) member A1 decreases expression EXP bexarotene results in decreased expression of DNAJA1 mRNA CTD PMID:16648578 NCBI chr 5:55,842,414...55,853,326
Ensembl chr 5:55,842,426...55,853,967
JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha decreases expression ISO bexarotene results in decreased expression of DNMT3A mRNA CTD PMID:17849452 NCBI chr 6:26,791,517...26,902,161
Ensembl chr 6:26,822,609...26,896,687
JBrowse link
G Dusp1 dual specificity phosphatase 1 decreases expression ISO
EXP
bexarotene results in decreased expression of DUSP1 mRNA CTD PMID:16648578 PMID:17178900 NCBI chr10:16,680,489...16,683,276 JBrowse link
G Dusp5 dual specificity phosphatase 5 decreases expression ISO bexarotene results in decreased expression of DUSP5 mRNA CTD PMID:17178900 NCBI chr 1:252,538,408...252,555,320
Ensembl chr 1:252,538,449...252,551,818
JBrowse link
G Dync1i2 dynein cytoplasmic 1 intermediate chain 2 decreases expression EXP bexarotene results in decreased expression of DYNC1I2 mRNA CTD PMID:16648578 NCBI chr 3:56,033,882...56,085,080
Ensembl chr 3:56,033,917...56,085,080
JBrowse link
G Ech1 enoyl-CoA hydratase 1 increases expression EXP bexarotene results in increased expression of ECH1 mRNA CTD PMID:23292798 NCBI chr 1:84,114,494...84,120,788
Ensembl chr 1:84,112,751...84,120,795
JBrowse link
G Echdc1 ethylmalonyl-CoA decarboxylase 1 increases expression EXP bexarotene results in increased expression of ECHDC1 mRNA CTD PMID:23292798 NCBI chr 1:28,476,354...28,507,173
Ensembl chr 1:28,476,200...28,507,319
JBrowse link
G Eci1 enoyl-CoA delta isomerase 1 increases expression EXP bexarotene results in increased expression of ECI1 mRNA CTD PMID:16648578 NCBI chr10:13,456,715...13,470,061
Ensembl chr10:13,456,563...13,470,061
JBrowse link
G Ednrb endothelin receptor type B increases expression EXP bexarotene results in increased expression of EDNRB mRNA CTD PMID:16648578 NCBI chr15:80,640,839...80,672,115
Ensembl chr15:80,643,043...80,672,115
JBrowse link
G Egf epidermal growth factor increases expression EXP bexarotene results in increased expression of EGF mRNA CTD PMID:16648578 NCBI chr 2:218,219,408...218,302,370
Ensembl chr 2:218,219,415...218,302,064
JBrowse link
G Egr1 early growth response 1 multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in decreased expression of EGR1 mRNA CTD PMID:17630414 NCBI chr18:26,463,333...26,465,531
Ensembl chr18:26,462,981...26,466,766
JBrowse link
G Egr3 early growth response 3 decreases expression ISO bexarotene results in decreased expression of EGR3 mRNA CTD PMID:17178900 NCBI chr15:45,150,335...45,156,052
Ensembl chr15:45,150,567...45,154,627
JBrowse link
G Ehhadh enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase multiple interactions
increases expression
EXP [Tamoxifen co-treated with bexarotene] results in increased expression of EHHADH mRNA
bexarotene results in increased expression of EHHADH mRNA
CTD PMID:16648578 PMID:17630414 NCBI chr11:79,241,927...79,275,173
Ensembl chr11:79,241,938...79,275,188
JBrowse link
G Eif1 eukaryotic translation initiation factor 1 decreases expression ISO bexarotene results in decreased expression of EIF1 mRNA CTD PMID:17178900 NCBI chr10:85,246,751...85,248,842
Ensembl chr10:85,246,764...85,427,327
JBrowse link
G Eif3c eukaryotic translation initiation factor 3, subunit C decreases expression EXP bexarotene results in decreased expression of EIF3C mRNA CTD PMID:17630414 NCBI chr 1:181,134,604...181,152,489
Ensembl chr 1:181,134,604...181,152,493
JBrowse link
G Elovl6 ELOVL fatty acid elongase 6 multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in increased expression of ELOVL6 mRNA CTD PMID:17630414 NCBI chr 2:218,063,682...218,174,767
Ensembl chr 2:218,063,804...218,171,186
JBrowse link
G Eno1 enolase 1 increases expression EXP bexarotene results in increased expression of ENO1 mRNA CTD PMID:16648578 NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336
JBrowse link
G Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 decreases expression EXP bexarotene results in decreased expression of ENPP2 mRNA CTD PMID:16648578 NCBI chr 7:86,202,345...86,325,050
Ensembl chr 7:86,202,350...86,324,827
JBrowse link
G Epha2 Eph receptor A2 decreases expression ISO bexarotene results in decreased expression of EPHA2 mRNA CTD PMID:17178900 NCBI chr 5:153,605,644...153,634,115
Ensembl chr 5:153,605,644...153,634,117
JBrowse link
G Ephx1 epoxide hydrolase 1 increases expression EXP bexarotene results in increased expression of EPHX1 mRNA CTD PMID:23292798 NCBI chr13:92,714,315...92,744,124
Ensembl chr13:92,714,315...92,790,235
JBrowse link
G Ephx2 epoxide hydrolase 2 increases expression EXP bexarotene results in increased expression of EPHX2 mRNA CTD PMID:23292798 NCBI chr15:40,289,901...40,327,632
Ensembl chr15:40,289,902...40,327,615
JBrowse link
G Erp29 endoplasmic reticulum protein 29 increases expression EXP bexarotene results in increased expression of ERP29 mRNA CTD PMID:16648578 NCBI chr12:35,089,698...35,095,952
Ensembl chr12:35,089,707...35,096,376
JBrowse link
G Esr1 estrogen receptor 1 decreases expression ISO bexarotene results in decreased expression of ESR1 mRNA CTD PMID:17849452 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions ISO bexarotene binds to and results in decreased activity of ESR2 protein CTD PMID:25752796 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
JBrowse link
G F2 coagulation factor II decreases expression EXP bexarotene results in decreased expression of F2 mRNA CTD PMID:16648578 NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486
JBrowse link
G Fabp1 fatty acid binding protein 1 decreases expression EXP bexarotene results in decreased expression of FABP1 mRNA CTD PMID:16648578 NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788
JBrowse link
G Fabp2 fatty acid binding protein 2 decreases expression
multiple interactions
EXP bexarotene results in decreased expression of FABP2 mRNA
[Tamoxifen co-treated with bexarotene] results in decreased expression of FABP2 mRNA
CTD PMID:17630414 NCBI chr 2:211,040,032...211,044,089
Ensembl chr 2:211,040,032...211,044,089
JBrowse link
G Fabp3 fatty acid binding protein 3 multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in increased expression of FABP3 mRNA CTD PMID:17630414 NCBI chr 5:142,651,962...142,658,707
Ensembl chr 5:142,651,956...142,658,718
JBrowse link
G Fabp4 fatty acid binding protein 4 increases expression ISO bexarotene results in increased expression of FABP4 mRNA; bexarotene results in increased expression of FABP4 protein CTD PMID:21622945 PMID:25932594 NCBI chr 2:91,580,858...91,585,578
Ensembl chr 2:91,580,885...91,585,578
JBrowse link
G Fads2 fatty acid desaturase 2 increases expression
multiple interactions
EXP bexarotene results in increased expression of FADS2 mRNA
[Tamoxifen co-treated with bexarotene] results in increased expression of FADS2 mRNA
CTD PMID:17630414 NCBI chr 1:206,707,384...206,747,333
Ensembl chr 1:206,708,783...206,748,789
JBrowse link
G Fam13a family with sequence similarity 13, member A decreases expression EXP bexarotene results in decreased expression of FAM13A mRNA CTD PMID:17630414 NCBI chr 4:88,056,521...88,155,782
Ensembl chr 4:88,058,403...88,155,860
JBrowse link
G Fasn fatty acid synthase multiple interactions
increases expression
EXP
ISO
[Tamoxifen co-treated with bexarotene] results in increased expression of FASN mRNA
[Bexarotene co-treated with GW 3965] results in increased expression of FASN mRNA; [Bexarotene co-treated with paxilline] results in increased expression of FASN mRNA; [Bexarotene co-treated with TO-901317] results in increased expression of FASN mRNA
bexarotene results in increased expression of FASN mRNA
CTD PMID:16648578 PMID:17630414 PMID:32123961 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
JBrowse link
G Fcgr2a Fc fragment of IgG receptor IIa multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in decreased expression of FCGR3 mRNA CTD PMID:17630414 NCBI chr13:83,280,782...83,297,535
Ensembl chr13:83,280,784...83,295,967
JBrowse link
G Fcgr2b Fc fragment of IgG receptor IIb multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in decreased expression of FCGR2B mRNA CTD PMID:17630414 NCBI chr13:83,191,253...83,207,776
Ensembl chr13:83,193,163...83,207,778
JBrowse link
G Fcna ficolin A multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in decreased expression of FCNA mRNA CTD PMID:17630414 NCBI chr 3:8,445,904...8,449,128
Ensembl chr 3:8,445,907...8,449,105
JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 increases expression EXP bexarotene results in increased expression of FDFT1 mRNA CTD PMID:16648578 NCBI chr15:37,412,143...37,440,198
Ensembl chr15:37,412,146...37,440,287
JBrowse link
G Fga fibrinogen alpha chain decreases expression EXP bexarotene results in decreased expression of FGA mRNA CTD PMID:16648578 NCBI chr 2:168,365,364...168,381,533
Ensembl chr 2:168,374,120...168,381,528
JBrowse link
G Fgb fibrinogen beta chain decreases expression EXP bexarotene results in decreased expression of FGB mRNA CTD PMID:16648578 NCBI chr 2:168,394,901...168,402,863
Ensembl chr 2:168,394,916...168,405,979
JBrowse link
G Fgg fibrinogen gamma chain decreases expression EXP bexarotene results in decreased expression of FGG mRNA CTD PMID:16648578 NCBI chr 2:168,354,880...168,362,325
Ensembl chr 2:168,355,013...168,362,322
JBrowse link
G Fh fumarate hydratase decreases expression EXP bexarotene results in decreased expression of FH1 mRNA CTD PMID:16648578 NCBI chr13:87,524,331...87,550,215
Ensembl chr13:87,524,337...87,550,266
JBrowse link
G Fmo1 flavin containing dimethylaniline monoxygenase 1 decreases expression EXP bexarotene results in decreased expression of FMO1 mRNA CTD PMID:16648578 NCBI chr13:75,182,184...75,214,439
Ensembl chr13:75,182,176...75,214,647
JBrowse link
G Fn1 fibronectin 1 increases expression EXP bexarotene results in increased expression of FN1 mRNA CTD PMID:16648578 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
JBrowse link
G Foxa1 forkhead box A1 increases expression EXP bexarotene results in increased expression of FOXA1 mRNA CTD PMID:16648578 NCBI chr 6:75,099,907...75,136,534
Ensembl chr 6:75,103,503...75,136,188
JBrowse link
G Foxa2 forkhead box A2 decreases expression EXP bexarotene results in decreased expression of FOXA2 mRNA CTD PMID:16648578 NCBI chr 3:135,470,123...135,474,326
Ensembl chr 3:135,470,131...135,474,326
JBrowse link
G Galr2 galanin receptor 2 increases expression EXP bexarotene results in increased expression of GALR2 mRNA CTD PMID:16648578 NCBI chr10:101,513,689...101,517,176
Ensembl chr10:101,514,471...101,517,176
JBrowse link
G Gars glycyl-tRNA synthetase decreases expression ISO Bexarotene results in decreased expression of GARS1 mRNA CTD PMID:17178900 NCBI chr 4:84,171,596...84,212,609
Ensembl chr 4:84,171,596...84,212,609
JBrowse link
G Gas6 growth arrest specific 6 decreases expression
multiple interactions
EXP bexarotene results in decreased expression of GAS6 mRNA
[bexarotene co-treated with Tamoxifen] results in decreased expression of GAS6 mRNA
CTD PMID:16648578 PMID:17630414 NCBI chr16:76,045,430...76,075,904
Ensembl chr16:76,045,426...76,075,904
JBrowse link
G Gas7 growth arrest specific 7 increases expression EXP bexarotene results in increased expression of GAS7 mRNA CTD PMID:16648578 NCBI chr10:52,152,728...52,383,276
Ensembl chr10:52,152,493...52,383,276
JBrowse link
G Gc GC, vitamin D binding protein decreases expression EXP bexarotene results in decreased expression of GC mRNA CTD PMID:16648578 NCBI chr14:18,632,146...18,667,563
Ensembl chr14:18,632,135...18,667,567
JBrowse link
G Gcgr glucagon receptor decreases expression EXP bexarotene results in decreased expression of GCGR mRNA CTD PMID:16648578 NCBI chr10:105,808,474...105,816,641
Ensembl chr10:105,808,473...105,816,640
JBrowse link
G Ghrh growth hormone releasing hormone increases expression EXP bexarotene results in increased expression of GHRH mRNA CTD PMID:16648578 NCBI chr 3:145,992,762...146,012,528
Ensembl chr 3:145,992,763...146,011,889
JBrowse link
G Glra3 glycine receptor, alpha 3 increases expression EXP bexarotene results in increased expression of GLRA3 mRNA CTD PMID:16648578 NCBI chr16:34,205,431...34,848,332
Ensembl chr16:34,204,811...34,848,753
JBrowse link
G Gosr1 golgi SNAP receptor complex member 1 increases expression EXP bexarotene results in increased expression of GOSR1 mRNA CTD PMID:16648578 NCBI chr10:61,570,499...61,607,287
Ensembl chr10:61,450,494...61,607,177
Ensembl chr10:61,450,494...61,607,177
JBrowse link
G Gpd1 glycerol-3-phosphate dehydrogenase 1 increases expression EXP bexarotene results in increased expression of GPD1 mRNA CTD PMID:23292798 NCBI chr 7:130,842,526...130,851,530
Ensembl chr 7:130,844,138...130,851,529
JBrowse link
G Gpd2 glycerol-3-phosphate dehydrogenase 2 multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in increased expression of GPD2 mRNA CTD PMID:17630414 NCBI chr 3:41,800,552...41,937,729
Ensembl chr 3:41,801,930...41,936,901
JBrowse link
G Gpm6a glycoprotein m6a multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in increased expression of GPM6A mRNA CTD PMID:17630414 NCBI chr16:36,641,282...36,973,477
Ensembl chr16:36,641,284...36,973,475
JBrowse link
G Gpm6b glycoprotein m6b increases expression ISO bexarotene results in increased expression of GPM6B mRNA CTD PMID:17178900 NCBI chr  X:28,057,788...28,204,409
Ensembl chr  X:28,059,450...28,204,211
JBrowse link
G Gpx4 glutathione peroxidase 4 increases expression EXP bexarotene results in increased expression of GPX4 mRNA CTD PMID:16648578 NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982
JBrowse link
G Grin2c glutamate ionotropic receptor NMDA type subunit 2C increases expression EXP bexarotene results in increased expression of GRIN2C mRNA CTD PMID:17630414 NCBI chr10:100,488,430...100,507,083
Ensembl chr10:100,488,431...100,506,427
JBrowse link
G Grina glutamate ionotropic receptor NMDA type subunit associated protein 1 increases expression EXP bexarotene results in increased expression of GRINA mRNA CTD PMID:16648578 NCBI chr 7:107,962,194...107,965,368
Ensembl chr 7:107,962,207...107,965,366
JBrowse link
G Grk2 G protein-coupled receptor kinase 2 increases expression EXP bexarotene results in increased expression of GRK2 mRNA CTD PMID:16648578 NCBI chr 1:201,581,480...201,601,580
Ensembl chr 1:201,581,480...201,601,582
JBrowse link
G Gsta5 glutathione S-transferase alpha 5 increases expression EXP bexarotene results in increased expression of GSTA5 mRNA CTD PMID:23292798 NCBI chr 8:79,105,561...79,117,472
Ensembl chr 8:79,105,661...79,117,472
JBrowse link
G Gstm3l glutathione S-transferase mu 3-like increases expression EXP bexarotene results in increased expression of GSTM5 mRNA CTD PMID:17630414 NCBI chr 2:195,590,450...195,612,578
Ensembl chr 2:195,607,289...195,612,475
JBrowse link
G Gys2 glycogen synthase 2 decreases expression
increases expression
EXP bexarotene results in decreased expression of GYS2 mRNA
bexarotene results in increased expression of GYS2 mRNA
CTD PMID:16648578 PMID:23292798 NCBI chr 4:175,365,054...175,406,228
Ensembl chr 4:175,365,054...175,406,228
JBrowse link
G H2az1 H2A.Z variant histone 1 decreases expression EXP Bexarotene results in decreased expression of H2AZ1 mRNA CTD PMID:16648578 NCBI chr 2:226,355,769...226,357,878
Ensembl chr 2:226,355,708...226,358,485
JBrowse link
G Hao2 hydroxyacid oxidase 2 decreases expression EXP bexarotene results in decreased expression of HAO2 mRNA CTD PMID:17630414 NCBI chr 2:186,200,137...186,232,997
Ensembl chr 2:186,200,504...186,224,425
JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 decreases expression ISO bexarotene results in decreased expression of HERPUD1 mRNA CTD PMID:17178900 NCBI chr19:10,598,411...10,609,002
Ensembl chr19:10,598,417...10,618,424
JBrowse link
G Hmgb2 high mobility group box 2 decreases expression EXP bexarotene results in decreased expression of HMGB2 mRNA CTD PMID:16648578 NCBI chr16:32,710,651...32,713,230
Ensembl chr16:32,710,658...32,713,140
JBrowse link
G Homer1 homer scaffold protein 1 increases expression EXP bexarotene results in increased expression of HOMER1 mRNA CTD PMID:16648578 NCBI chr 2:24,542,777...24,645,715
Ensembl chr 2:24,543,093...24,644,785
JBrowse link
G Hp haptoglobin decreases expression EXP bexarotene results in decreased expression of HP mRNA CTD PMID:16648578 NCBI chr19:37,539,626...37,544,178
Ensembl chr19:37,539,627...37,544,523
JBrowse link
G Hpgds hematopoietic prostaglandin D synthase increases expression EXP bexarotene results in increased expression of HPGDS mRNA CTD PMID:16648578 NCBI chr 4:94,368,426...94,397,931
Ensembl chr 4:94,373,342...94,397,883
JBrowse link
G Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 increases expression
multiple interactions
ISO Bexarotene results in increased expression of HSD11B2 mRNA
Bexarotene results in increased expression of and results in increased activity of HSD11B2 protein; Cycloheximide promotes the reaction [Bexarotene results in increased expression of HSD11B2 mRNA]; Dactinomycin inhibits the reaction [Bexarotene results in increased expression of HSD11B2 mRNA]; LG 100754 inhibits the reaction [Bexarotene results in increased activity of HSD11B2 protein]; RXRA protein affects the reaction [Bexarotene results in increased expression of HSD11B2 mRNA]; RXRA protein affects the reaction [Bexarotene results in increased expression of HSD11B2 protein]
CTD PMID:31927052 NCBI chr19:33,397,656...33,402,899
Ensembl chr19:33,397,656...33,402,899
JBrowse link
G Hsd17b12 hydroxysteroid (17-beta) dehydrogenase 12 increases expression EXP bexarotene results in increased expression of HSD17B12 mRNA CTD PMID:16648578 NCBI chr 3:79,990,048...80,113,556
Ensembl chr 3:79,990,056...80,113,617
JBrowse link
G Hsd17b2 hydroxysteroid (17-beta) dehydrogenase 2 decreases expression EXP bexarotene results in decreased expression of HSD17B2 mRNA CTD PMID:16648578 NCBI chr19:45,753,576...45,825,203
Ensembl chr19:45,753,574...45,825,202
JBrowse link
G Hspa4 heat shock protein family A (Hsp70) member 4 decreases expression EXP bexarotene results in decreased expression of HSPA4 mRNA CTD PMID:16648578 NCBI chr10:37,408,025...37,449,080
Ensembl chr10:37,408,025...37,449,001
JBrowse link
G Hspa9 heat shock protein family A (Hsp70) member 9 increases expression EXP bexarotene results in increased expression of HSPA9 mRNA CTD PMID:16648578 NCBI chr18:26,536,131...26,554,294
Ensembl chr18:26,535,798...26,554,292
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 increases expression EXP bexarotene results in increased expression of HSPB1 mRNA CTD PMID:16648578 NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743
JBrowse link
G Hsph1 heat shock protein family H (Hsp110) member 1 decreases expression EXP bexarotene results in decreased expression of HSPH1 mRNA CTD PMID:16648578 NCBI chr12:5,390,916...5,410,224
Ensembl chr12:5,390,922...5,410,224
JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein increases expression ISO bexarotene results in increased expression of ID1 mRNA; bexarotene results in increased expression of ID1 protein CTD PMID:17178900 NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419
JBrowse link
G Ier2 immediate early response 2 decreases expression ISO bexarotene results in decreased expression of IER2 mRNA CTD PMID:17178900 NCBI chr19:23,494,551...23,496,075
Ensembl chr19:23,494,184...23,499,211
JBrowse link
G Ifitm1 interferon induced transmembrane protein 1 multiple interactions EXP [Bexarotene co-treated with Tamoxifen] results in decreased expression of IFITM1 mRNA CTD PMID:17630414 NCBI chr 1:196,067,163...196,069,169
Ensembl chr 1:196,067,963...196,069,169
JBrowse link
G Ifngr1 interferon gamma receptor 1 increases expression EXP bexarotene results in increased expression of IFNGR1 mRNA CTD PMID:16648578 NCBI chr 1:14,333,167...14,351,799
Ensembl chr 1:14,333,187...14,351,785
JBrowse link
G Igf1 insulin-like growth factor 1 decreases expression EXP bexarotene results in decreased expression of IGF1 protein CTD PMID:15591091 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Igf2 insulin-like growth factor 2 increases expression EXP bexarotene results in increased expression of IGF2 mRNA CTD PMID:16648578 NCBI chr 1:197,814,409...197,831,802
Ensembl chr 1:197,814,410...197,823,018
JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 increases expression EXP bexarotene results in increased expression of IGFBP1 mRNA CTD PMID:16648578 NCBI chr14:82,047,415...82,052,482
Ensembl chr14:82,047,415...82,052,482
JBrowse link
G Igfbp2 insulin-like growth factor binding protein 2 increases expression
multiple interactions
EXP bexarotene results in increased expression of IGFBP2 mRNA
[Tamoxifen co-treated with bexarotene] results in increased expression of IGFBP2 mRNA
CTD PMID:16648578 PMID:17630414 NCBI chr 9:74,415,574...74,442,945
Ensembl chr 9:74,415,546...74,442,937
JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 multiple interactions
decreases expression
EXP [bexarotene co-treated with Tamoxifen] results in decreased expression of IGFBP3 mRNA
bexarotene results in decreased expression of IGFBP3 mRNA
CTD PMID:16648578 PMID:17630414 NCBI chr14:82,056,347...82,064,083
Ensembl chr14:82,056,347...82,064,083
JBrowse link
G Igfbp6 insulin-like growth factor binding protein 6 increases expression ISO bexarotene results in increased expression of IGFBP6 mRNA; bexarotene results in increased expression of IGFBP6 protein CTD PMID:17178900 NCBI chr 7:133,276,309...133,280,944
Ensembl chr 7:133,276,234...133,280,966
JBrowse link
G Igfbp7 insulin-like growth factor binding protein 7 multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in decreased expression of IGFBP7 mRNA CTD PMID:17630414 NCBI chr14:30,737,414...30,797,317
Ensembl chr14:30,737,164...30,797,314
JBrowse link
G Il15 interleukin 15 increases expression ISO bexarotene results in increased expression of IL15 mRNA CTD PMID:17178900 NCBI chr19:25,640,013...25,706,818
Ensembl chr19:25,640,251...25,706,820
JBrowse link
G Il18 interleukin 18 decreases expression EXP bexarotene results in decreased expression of IL18 mRNA CTD PMID:16648578 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
JBrowse link
G Il4 interleukin 4 decreases expression ISO bexarotene results in decreased expression of IL4 protein CTD PMID:15781672 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Il6r interleukin 6 receptor decreases expression EXP bexarotene results in decreased expression of IL6RA mRNA CTD PMID:16648578 NCBI chr 2:175,289,157...175,347,719
Ensembl chr 2:175,298,686...175,347,536
JBrowse link
G Ins2 insulin 2 multiple interactions ISO [bexarotene co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 protein; bexarotene inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; bexarotene inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of DMP1 mRNA]; bexarotene inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA]; bexarotene promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of NR1H3 mRNA]; bexarotene promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SREBF1 mRNA]
[[Dexamethasone co-treated with INS protein co-treated with 1-Methyl-3-isobutylxanthine] co-treated with bexarotene] results in increased expression of SLC27A1 mRNA; [Dexamethasone co-treated with INS protein co-treated with 1-Methyl-3-isobutylxanthine] results in increased susceptibility to bexarotene
CTD PMID:10777552 PMID:25932594 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
JBrowse link
G Insig1 insulin induced gene 1 increases expression EXP bexarotene results in increased expression of INSIG1 mRNA CTD PMID:16648578 NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952
JBrowse link
G Insrr insulin receptor-related receptor increases expression EXP bexarotene results in increased expression of INSRR mRNA CTD PMID:16648578 NCBI chr 2:173,255,335...173,274,800
Ensembl chr 2:173,255,414...173,274,800
JBrowse link
G Irf1 interferon regulatory factor 1 increases expression EXP bexarotene results in increased expression of IRF1 mRNA CTD PMID:16648578 NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166
JBrowse link
G Itga7 integrin subunit alpha 7 decreases expression EXP bexarotene results in decreased expression of ITGA7 mRNA CTD PMID:16648578 NCBI chr 7:1,360,125...1,388,886
Ensembl chr 7:1,359,940...1,388,450
JBrowse link
G Itgb6 integrin subunit beta 6 increases expression ISO bexarotene results in increased expression of ITGB6 mRNA CTD PMID:17178900 NCBI chr 3:45,046,295...45,170,532
Ensembl chr 3:45,048,044...45,121,671
JBrowse link
G Itih3 inter-alpha trypsin inhibitor, heavy chain 3 decreases expression EXP bexarotene results in decreased expression of ITIH3 mRNA CTD PMID:16648578 NCBI chr16:6,101,922...6,117,154
Ensembl chr16:6,101,930...6,116,924
JBrowse link
G Itm2a integral membrane protein 2A increases expression ISO bexarotene results in increased expression of ITM2A mRNA CTD PMID:17178900 NCBI chr  X:72,486,383...72,492,344
Ensembl chr  X:72,486,381...72,492,363
JBrowse link
G Itpr1 inositol 1,4,5-trisphosphate receptor, type 1 increases expression ISO bexarotene results in increased expression of ITPR1 mRNA CTD PMID:17178900 NCBI chr 4:141,187,377...141,554,240
Ensembl chr 4:141,187,418...141,510,491
JBrowse link
G Ivl involucrin decreases expression ISO bexarotene results in decreased expression of IVL mRNA CTD PMID:8853895 NCBI chr 2:178,146,694...178,160,807
Ensembl chr 2:178,147,061...178,149,100
JBrowse link
G Jup junction plakoglobin increases expression EXP bexarotene results in increased expression of JUP mRNA CTD PMID:16648578 NCBI chr10:85,300,438...85,327,378
Ensembl chr10:85,300,440...85,327,057
JBrowse link
G Kcnma1 potassium calcium-activated channel subfamily M alpha 1 multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in decreased expression of KCNMA1 mRNA CTD PMID:17630414 NCBI chr15:302,078...1,001,198
Ensembl chr15:302,214...1,001,198
JBrowse link
G Kcnt1 potassium sodium-activated channel subfamily T member 1 increases expression EXP bexarotene results in increased expression of KCNT1 mRNA CTD PMID:16648578 NCBI chr 3:8,682,964...8,736,615
Ensembl chr 3:8,682,113...8,736,667
JBrowse link
G Klf10 Kruppel-like factor 10 decreases expression ISO bexarotene results in decreased expression of KLF10 mRNA CTD PMID:17178900 NCBI chr 7:69,467,658...69,473,726
Ensembl chr 7:69,465,619...69,473,994
JBrowse link
G Klf9 Kruppel-like factor 9 increases expression
decreases expression
ISO
EXP
bexarotene results in increased expression of KLF9 mRNA
bexarotene results in decreased expression of KLF9 mRNA
CTD PMID:16648578 PMID:26096596 NCBI chr 1:220,700,108...220,725,029
Ensembl chr 1:220,700,108...220,725,037
JBrowse link
G Kng2 kininogen 2 increases expression
decreases expression
ISO
EXP
bexarotene results in increased expression of KNG1 mRNA
bexarotene results in decreased expression of KNG1 mRNA
CTD PMID:16648578 PMID:17849452 NCBI chr11:77,913,876...77,936,247 JBrowse link
G Krt14 keratin 14 decreases expression ISO bexarotene results in decreased expression of KRT14 mRNA CTD PMID:8853895 NCBI chr10:85,137,932...85,141,990
Ensembl chr10:85,066,802...85,171,799
JBrowse link
G Krt15 keratin 15 increases expression ISO bexarotene results in increased expression of KRT15 mRNA CTD PMID:17178900 NCBI chr10:85,066,797...85,070,614 JBrowse link
G Krt17 keratin 17 decreases expression ISO bexarotene results in decreased expression of KRT17 mRNA; bexarotene results in decreased expression of KRT17 protein CTD PMID:17178900 NCBI chr10:85,178,673...85,183,392
Ensembl chr10:85,178,675...85,183,392
JBrowse link
G Krt5 keratin 5 decreases expression ISO bexarotene results in decreased expression of KRT5 mRNA CTD PMID:8853895 NCBI chr 7:132,846,355...132,851,986
Ensembl chr 7:132,846,136...132,851,850
JBrowse link
G Ldhb lactate dehydrogenase B decreases expression EXP bexarotene results in decreased expression of LDHB mRNA CTD PMID:16648578 NCBI chr 4:175,428,382...175,446,403
Ensembl chr 4:175,428,385...175,446,403
JBrowse link
G Lgals3 galectin 3 decreases expression EXP bexarotene results in decreased expression of LGALS3 mRNA CTD PMID:16648578 NCBI chr15:20,620,083...20,632,019
Ensembl chr15:20,607,692...20,632,025
JBrowse link
G Lgals5 galectin 5 increases expression EXP bexarotene results in increased expression of LGALS5 mRNA CTD PMID:16648578 NCBI chr10:63,853,949...63,857,198
Ensembl chr10:63,853,935...63,857,153
JBrowse link
G Lifr LIF receptor subunit alpha multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in decreased expression of LIFR mRNA CTD PMID:17630414 NCBI chr 2:56,224,393...56,292,988
Ensembl chr 2:56,250,120...56,286,699
JBrowse link
G Lipa lipase A, lysosomal acid type decreases expression EXP bexarotene results in decreased expression of LIP1 mRNA CTD PMID:16648578 NCBI chr 1:232,024,351...232,167,329
Ensembl chr 1:232,024,356...232,057,633
JBrowse link
G Lipe lipase E, hormone sensitive type decreases expression EXP bexarotene results in decreased expression of LIPE mRNA CTD PMID:16648578 NCBI chr 1:80,965,612...80,984,313
Ensembl chr 1:80,965,627...80,984,310
JBrowse link
G Lman1 lectin, mannose-binding, 1 decreases expression EXP bexarotene results in decreased expression of LMAN1 mRNA CTD PMID:16648578 NCBI chr18:59,508,996...59,530,873
Ensembl chr18:59,508,996...59,530,851
JBrowse link
G Lox lysyl oxidase decreases expression EXP bexarotene results in decreased expression of LOX mRNA CTD PMID:16648578 NCBI chr18:45,964,311...46,041,477
Ensembl chr18:45,967,343...46,041,477
JBrowse link
G Loxl2 lysyl oxidase-like 2 increases expression ISO bexarotene results in increased expression of LOXL2 mRNA CTD PMID:17178900 NCBI chr15:44,683,449...44,773,067
Ensembl chr15:44,683,880...44,773,067
JBrowse link
G Lre3 LINE retrotransposable element 3 increases expression EXP bexarotene results in increased expression of LRE3 mRNA CTD PMID:16648578
G Lrg1 leucine-rich alpha-2-glycoprotein 1 multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in decreased expression of LRG1 mRNA CTD PMID:17630414 NCBI chr 9:947,516...949,773
Ensembl chr 9:947,516...949,813
JBrowse link
G Lrp2 LDL receptor related protein 2 decreases expression EXP bexarotene results in decreased expression of LRP2 mRNA CTD PMID:16648578 NCBI chr 3:54,189,305...54,346,769
Ensembl chr 3:54,189,308...54,346,708
JBrowse link
G Lum lumican decreases expression EXP bexarotene results in decreased expression of LUM mRNA CTD PMID:16648578 NCBI chr 7:32,358,990...32,365,794
Ensembl chr 7:32,358,614...32,365,793
JBrowse link
G Lypla1 lysophospholipase 1 decreases expression EXP bexarotene results in decreased expression of LYPLA1 mRNA CTD PMID:16648578 NCBI chr 5:14,679,605...14,708,774
Ensembl chr 5:14,679,606...14,708,746
JBrowse link
G Lyst lysosomal trafficking regulator increases expression EXP bexarotene results in increased expression of LYST mRNA CTD PMID:17630414 NCBI chr17:86,241,384...86,443,501 JBrowse link
G Lyve1 lymphatic vessel endothelial hyaluronan receptor 1 multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in decreased expression of XLKD1 mRNA CTD PMID:17630414 NCBI chr 1:164,962,872...164,976,309
Ensembl chr 1:164,962,872...164,976,309
JBrowse link
G Maf MAF bZIP transcription factor increases expression ISO bexarotene results in increased expression of MAF mRNA CTD PMID:17178900 NCBI chr19:43,353,867...43,713,162
Ensembl chr19:43,360,342...43,712,365
JBrowse link
G Maff MAF bZIP transcription factor F decreases expression ISO bexarotene results in decreased expression of MAFF mRNA CTD PMID:17178900 NCBI chr 7:110,912,499...110,923,851
Ensembl chr 7:110,912,499...110,923,851
JBrowse link
G Maob monoamine oxidase B decreases expression EXP bexarotene results in decreased expression of MAOB mRNA CTD PMID:16648578 NCBI chr  X:5,907,327...6,010,996
Ensembl chr  X:5,907,266...6,011,003
JBrowse link
G Map1b microtubule-associated protein 1B increases expression EXP bexarotene results in increased expression of MAP1B mRNA CTD PMID:16648578 NCBI chr 2:30,817,261...30,910,458
Ensembl chr 2:30,817,261...30,910,317
JBrowse link
G Map2 microtubule-associated protein 2 increases expression EXP bexarotene results in increased expression of MAP2 mRNA CTD PMID:16648578 NCBI chr 9:67,723,422...67,981,886
Ensembl chr 9:67,723,371...67,979,809
JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 increases expression EXP bexarotene results in increased expression of MAP3K1 mRNA CTD PMID:16648578 NCBI chr 2:43,348,572...43,414,706
Ensembl chr 2:43,350,098...43,414,463
JBrowse link
G Map3k12 mitogen activated protein kinase kinase kinase 12 increases expression EXP bexarotene results in increased expression of MAP3K12 mRNA CTD PMID:16648578 NCBI chr 7:133,630,267...133,648,464
Ensembl chr 7:133,630,835...133,640,789
JBrowse link
G Mark1 microtubule affinity regulating kinase 1 increases expression EXP bexarotene results in increased expression of MARK1 mRNA CTD PMID:16648578 NCBI chr13:96,450,189...96,555,304
Ensembl chr13:96,451,487...96,555,173
JBrowse link
G Me1 malic enzyme 1 increases expression EXP bexarotene results in increased expression of ME1 mRNA CTD PMID:16648578 PMID:23292798 NCBI chr 8:87,549,043...87,660,251
Ensembl chr 8:87,549,043...87,660,304
JBrowse link
G Mfsd2a major facilitator superfamily domain containing 2A decreases expression EXP bexarotene results in decreased expression of MFSD2A mRNA CTD PMID:17630414 NCBI chr 5:135,225,801...135,240,744
Ensembl chr 5:135,225,816...135,240,690
JBrowse link
G Mgp matrix Gla protein multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in decreased expression of MGP mRNA CTD PMID:17630414 NCBI chr 4:169,766,290...169,769,612
Ensembl chr 4:169,766,279...169,769,667
JBrowse link
G Mllt11 MLLT11, transcription factor 7 cofactor increases expression ISO bexarotene results in increased expression of MLLT11 mRNA CTD PMID:17178900 NCBI chr 2:182,795,790...182,804,960
Ensembl chr 2:182,795,790...182,797,199
JBrowse link
G Mlxipl MLX interacting protein-like multiple interactions ISO [Bexarotene co-treated with GW 3965] results in decreased expression of MLXIPL mRNA; [Bexarotene co-treated with TO-901317] results in decreased expression of MLXIPL mRNA CTD PMID:32123961 NCBI chr12:21,542,964...21,577,120
Ensembl chr12:21,543,576...21,577,112
JBrowse link
G Mmp1 matrix metallopeptidase 1 decreases expression ISO bexarotene results in decreased expression of MMP1 mRNA CTD PMID:17178900 NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097
JBrowse link
G Mmp14 matrix metallopeptidase 14 decreases expression EXP bexarotene results in decreased expression of MMP14 mRNA CTD PMID:16648578 NCBI chr15:27,887,795...27,897,020
Ensembl chr15:27,887,727...27,899,864
JBrowse link
G Mrc1 mannose receptor, C type 1 multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in decreased expression of MRC1 mRNA CTD PMID:17630414 NCBI chr17:77,249,187...77,330,857
Ensembl chr17:77,249,187...77,330,857
JBrowse link
G Mt-co2 mitochondrially encoded cytochrome c oxidase II decreases expression ISO bexarotene results in decreased expression of COX2 mRNA; bexarotene results in decreased expression of COX2 protein CTD PMID:17178900 Ensembl chr MT:7,006...7,689 JBrowse link
G Mthfd2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase decreases expression ISO bexarotene results in decreased expression of MTHFD2 mRNA CTD PMID:17178900 NCBI chr 4:115,811,135...115,822,663
Ensembl chr 4:115,811,139...115,822,608
JBrowse link
G Muc1 mucin 1, cell surface associated increases expression EXP bexarotene results in increased expression of MUC1 mRNA CTD PMID:16648578 NCBI chr 2:174,635,559...174,640,738
Ensembl chr 2:174,635,995...174,640,733
JBrowse link
G Mug1 murinoglobulin 1 decreases expression EXP bexarotene results in decreased expression of MUG1 mRNA CTD PMID:16648578 NCBI chr 4:155,076,270...155,130,051
Ensembl chr 4:155,076,312...155,130,051
JBrowse link
G Napa NSF attachment protein alpha increases expression EXP bexarotene results in increased expression of NAPA mRNA CTD PMID:16648578 NCBI chr 1:76,787,036...76,805,869
Ensembl chr 1:76,786,932...76,805,869
JBrowse link
G Nat8 N-acetyltransferase 8 decreases expression EXP bexarotene results in decreased expression of NAT8 mRNA CTD PMID:17630414 NCBI chr 4:118,279,521...118,284,671
Ensembl chr 4:118,270,954...118,281,763
JBrowse link
G Ndufaf3 NADH:ubiquinone oxidoreductase complex assembly factor 3 increases expression EXP bexarotene results in increased expression of NDUFAF3 mRNA CTD PMID:16648578 NCBI chr 8:109,261,362...109,263,194
Ensembl chr 8:109,261,363...109,263,194
JBrowse link
G Neurod2 neuronal differentiation 2 increases expression EXP bexarotene results in increased expression of NEUROD2 mRNA CTD PMID:16648578 NCBI chr10:83,323,801...83,327,986
Ensembl chr10:83,324,442...83,327,986
JBrowse link
G Nim1k NIM1 serine/threonine protein kinase multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in increased expression of NIM1K mRNA CTD PMID:17630414 NCBI chr 2:51,670,764...51,714,782
Ensembl chr 2:51,670,772...51,714,762
JBrowse link
G Nol3 nucleolar protein 3 multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in increased expression of NOL3 mRNA CTD PMID:17630414 NCBI chr19:33,154,061...33,158,250
Ensembl chr19:33,154,062...33,158,250
JBrowse link
G Nos2 nitric oxide synthase 2 decreases expression ISO bexarotene results in decreased expression of NOS2 mRNA CTD PMID:17849452 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Npy neuropeptide Y increases expression EXP bexarotene results in increased expression of NPY mRNA CTD PMID:17630414 NCBI chr 4:78,881,294...78,888,495
Ensembl chr 4:78,881,264...78,888,495
JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 increases expression
multiple interactions
EXP
ISO
bexarotene results in increased expression of NR0B2 mRNA
[Bexarotene co-treated with GW 3965] results in increased expression of NR0B2 mRNA; [Bexarotene co-treated with paxilline] results in increased expression of NR0B2 mRNA; [Bexarotene co-treated with TO-901317] results in increased expression of NR0B2 mRNA
Bexarotene results in increased expression of NR0B2 mRNA
CTD PMID:17630414 PMID:23292798 PMID:32123961 NCBI chr 5:145,779,294...145,782,609
Ensembl chr 5:145,779,294...145,782,609
JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 multiple interactions
decreases expression
ISO [Bexarotene co-treated with GW 3965] results in increased expression of NR1H3 mRNA; [Bexarotene co-treated with paxilline] results in increased expression of NR1H3 mRNA; [Bexarotene co-treated with TO-901317] results in increased expression of NR1H3 mRNA; Bexarotene promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of NR1H3 mRNA]
Bexarotene results in decreased expression of NR1H3 mRNA
CTD PMID:25932594 PMID:32123961 NCBI chr 3:77,158,808...77,168,907
Ensembl chr 3:77,158,808...77,168,722
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases expression
multiple interactions
EXP
ISO
bexarotene results in increased expression of NR1I3 mRNA
Bexarotene binds to and results in increased activity of NR1I3 protein alternative form
CTD PMID:17630414 PMID:31312845 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
JBrowse link
G Nrip1 nuclear receptor interacting protein 1 multiple interactions ISO [Bexarotene co-treated with GW 3965] results in increased expression of NRIP1 mRNA; [Bexarotene co-treated with TO-901317] results in increased expression of NRIP1 mRNA CTD PMID:32123961 NCBI chr11:14,895,843...14,979,490
Ensembl chr11:14,895,553...14,981,761
JBrowse link
G Oaz1 ornithine decarboxylase antizyme 1 increases expression EXP bexarotene results in increased expression of OAZ1 mRNA CTD PMID:16648578 NCBI chr 7:8,883,855...8,886,315
Ensembl chr 7:8,883,851...8,886,310
JBrowse link
G Odc1 ornithine decarboxylase 1 decreases expression ISO bexarotene results in decreased expression of ODC1 mRNA CTD PMID:17178900 NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440
JBrowse link
G Odf3b outer dense fiber of sperm tails 3B multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in increased expression of ODF3B mRNA CTD PMID:17630414 NCBI chr 7:120,444,232...120,447,383
Ensembl chr 7:120,444,232...120,446,749
JBrowse link
G Olr1280 olfactory receptor 1280 increases expression EXP bexarotene results in increased expression of OLR1280 mRNA CTD PMID:16648578 NCBI chr 8:39,282,393...39,283,352
Ensembl chr 8:39,282,325...39,292,365
JBrowse link
G Orm1 orosomucoid 1 decreases expression EXP bexarotene results in decreased expression of ORM1 mRNA CTD PMID:16648578 NCBI chr 5:76,766,637...76,776,149
Ensembl chr 5:76,772,941...76,776,154
JBrowse link
G P4hb prolyl 4-hydroxylase subunit beta increases expression EXP bexarotene results in increased expression of P4HB mRNA CTD PMID:16648578 NCBI chr10:105,836,972...105,848,583
Ensembl chr10:105,836,982...105,848,500
JBrowse link
G Pde2a phosphodiesterase 2A decreases expression EXP bexarotene results in decreased expression of PDE2A mRNA CTD PMID:16648578 NCBI chr 1:155,823,590...155,915,434
Ensembl chr 1:155,813,180...155,915,434
JBrowse link
G Pdk2 pyruvate dehydrogenase kinase 2 increases expression EXP bexarotene results in increased expression of PDK2 mRNA CTD PMID:16648578 NCBI chr10:79,972,550...79,987,074
Ensembl chr10:79,972,556...79,987,085
JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 increases expression EXP bexarotene results in increased expression of PDK4 mRNA CTD PMID:16648578 NCBI chr 4:33,591,796...33,601,798
Ensembl chr 4:33,589,799...33,601,850
JBrowse link
G Per2 period circadian regulator 2 decreases expression ISO bexarotene results in decreased expression of PER2 mRNA CTD PMID:17178900 NCBI chr 9:92,007,289...92,049,551
Ensembl chr 9:92,007,296...92,049,459
JBrowse link
G Pex11a peroxisomal biogenesis factor 11 alpha multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in increased expression of PEX11A mRNA CTD PMID:17630414 NCBI chr 1:133,680,091...133,687,172
Ensembl chr 1:133,680,091...133,687,172
JBrowse link
G Pex19 peroxisomal biogenesis factor 19 decreases expression EXP bexarotene results in decreased expression of PEX19 mRNA CTD PMID:16648578 NCBI chr13:84,592,277...84,608,793
Ensembl chr13:84,592,312...84,608,608
JBrowse link
G Pf4 platelet factor 4 increases expression EXP bexarotene results in increased expression of PF4 mRNA CTD PMID:17630414 NCBI chr14:17,298,438...17,299,148
Ensembl chr14:17,298,308...17,299,365
JBrowse link
G Pgr progesterone receptor multiple interactions ISO bexarotene binds to and results in decreased activity of PGR protein CTD PMID:25752796 NCBI chr 8:6,073,216...6,131,552
Ensembl chr 8:6,072,673...6,131,344
JBrowse link
G Pik3cb phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta increases expression EXP bexarotene results in increased expression of PIK3CB mRNA CTD PMID:16648578 NCBI chr 8:99,594,600...99,699,772
Ensembl chr 8:99,594,644...99,699,663
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 multiple interactions ISO bexarotene promotes the reaction [rosiglitazone results in increased expression of PIK3R1 mRNA] CTD PMID:10548525 NCBI chr 2:32,878,942...32,963,611
Ensembl chr 2:32,882,032...32,963,631
JBrowse link
G Pik3r3 phosphoinositide-3-kinase regulatory subunit 3 increases expression EXP bexarotene results in increased expression of PIK3R3 mRNA CTD PMID:16648578 NCBI chr 5:129,700,925...129,772,591
Ensembl chr 5:129,701,229...129,772,583
JBrowse link
G Pkib cAMP-dependent protein kinase inhibitor beta multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in increased expression of PKIB mRNA CTD PMID:17630414 NCBI chr20:36,965,172...37,062,190
Ensembl chr20:36,905,340...37,062,187
JBrowse link
G Plagl1 PLAG1 like zinc finger 1 decreases expression EXP bexarotene results in decreased expression of PLAGL1 mRNA CTD PMID:16648578 NCBI chr 1:7,477,295...7,517,229
Ensembl chr 1:7,477,177...7,517,228
JBrowse link
G Plat plasminogen activator, tissue type increases expression ISO bexarotene results in increased expression of PLAT mRNA CTD PMID:17178900 NCBI chr16:69,240,582...69,265,177
Ensembl chr16:69,240,585...69,268,223
JBrowse link
G Plaur plasminogen activator, urokinase receptor decreases expression ISO bexarotene results in decreased expression of PLAUR mRNA CTD PMID:17178900 NCBI chr 1:80,053,441...80,068,384
Ensembl chr 1:80,050,324...80,068,595
JBrowse link
G Plin1 perilipin 1 increases expression ISO bexarotene results in increased expression of PLIN1 mRNA CTD PMID:25932594 NCBI chr 1:133,664,294...133,676,854
Ensembl chr 1:133,664,892...133,676,828
JBrowse link
G Plod2 procollagen lysine, 2-oxoglutarate 5-dioxygenase 2 increases expression ISO bexarotene results in increased expression of PLOD2 mRNA CTD PMID:17178900 NCBI chr 8:93,084,548...93,167,255
Ensembl chr 8:93,084,513...93,167,255
JBrowse link
G Pno1 partner of NOB1 homolog decreases expression ISO bexarotene results in decreased expression of PNO1 mRNA CTD PMID:17178900 NCBI chr14:91,609,711...91,618,280
Ensembl chr14:91,609,233...91,618,324
JBrowse link
G Pnrc1 proline-rich nuclear receptor coactivator 1 increases expression ISO bexarotene results in increased expression of PNRC1 mRNA CTD PMID:17178900 NCBI chr 5:47,647,070...47,657,832
Ensembl chr 5:47,647,071...47,650,161
JBrowse link
G Pola1 DNA polymerase alpha 1, catalytic subunit increases expression EXP bexarotene results in increased expression of POLA1 mRNA CTD PMID:16648578 NCBI chr  X:58,034,617...58,348,612
Ensembl chr  X:58,034,619...58,348,536
JBrowse link
G Pon1 paraoxonase 1 decreases expression EXP bexarotene results in decreased expression of PON1 mRNA CTD PMID:16648578 NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360
JBrowse link
G Por cytochrome p450 oxidoreductase increases expression EXP bexarotene results in increased expression of POR mRNA CTD PMID:16648578 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245
JBrowse link
G Ppp2cb protein phosphatase 2 catalytic subunit beta increases expression EXP bexarotene results in increased expression of PPP2CB mRNA CTD PMID:16648578 NCBI chr16:58,558,119...58,579,325
Ensembl chr16:58,558,122...58,579,576
JBrowse link
G Ppp2r1a protein phosphatase 2 scaffold subunit A alpha increases expression EXP bexarotene results in increased expression of PPP2R1A mRNA CTD PMID:16648578 NCBI chr 1:60,540,223...60,559,467
Ensembl chr 1:60,540,194...60,560,129
JBrowse link
G Ppt1 palmitoyl-protein thioesterase 1 decreases expression EXP bexarotene results in decreased expression of PPT1 mRNA CTD PMID:16648578 NCBI chr 5:135,121,176...135,141,076
Ensembl chr 5:135,121,163...135,142,048
JBrowse link
G Prdx6 peroxiredoxin 6 increases expression EXP bexarotene results in increased expression of PRDX6 mRNA CTD PMID:16648578 NCBI chr13:73,528,746...73,539,295
Ensembl chr13:73,528,210...73,539,355
JBrowse link
G Prkar2b protein kinase cAMP-dependent type II regulatory subunit beta decreases expression EXP bexarotene results in decreased expression of PRKAR2B mRNA CTD PMID:16648578 NCBI chr 6:48,563,659...48,653,933
Ensembl chr 6:48,563,662...48,653,933
JBrowse link
G Prl8a4 prolactin family 8, subfamily a, member 4 increases expression EXP bexarotene results in increased expression of PRL8A4 mRNA CTD PMID:16648578 NCBI chr17:37,429,960...37,436,053
Ensembl chr17:37,429,960...37,436,053
JBrowse link
G Prlhr prolactin releasing hormone receptor increases expression EXP bexarotene results in increased expression of PRLHR mRNA CTD PMID:16648578 NCBI chr 1:259,606,704...259,608,391
Ensembl chr 1:259,606,704...259,608,391
JBrowse link
G Prlr prolactin receptor multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in decreased expression of PRLR mRNA CTD PMID:17630414 NCBI chr 2:59,134,147...59,324,719
Ensembl chr 2:59,134,588...59,324,718
JBrowse link
G Prnp prion protein decreases expression EXP bexarotene results in decreased expression of PRNP mRNA CTD PMID:16648578 NCBI chr 3:119,186,073...119,201,513
Ensembl chr 3:119,177,485...119,203,937
JBrowse link
G Prom1 prominin 1 multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in decreased expression of PROM1 mRNA CTD PMID:17630414 NCBI chr14:66,989,545...67,094,534
Ensembl chr14:66,990,160...67,094,527
JBrowse link
G Prr15 proline rich 15 multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in increased expression of PRR15 mRNA CTD PMID:17630414 NCBI chr 4:83,432,002...83,435,582
Ensembl chr 4:83,431,758...83,437,436
JBrowse link
G Psap prosaposin increases expression EXP bexarotene results in increased expression of PSAP mRNA CTD PMID:16648578 NCBI chr20:28,214,229...28,240,501
Ensembl chr20:28,214,271...28,240,498
JBrowse link
G Psmc2 proteasome 26S subunit, ATPase 2 increases expression EXP bexarotene results in increased expression of PSMC2 mRNA CTD PMID:16648578 NCBI chr 4:13,255,851...13,270,102
Ensembl chr 4:13,255,856...13,270,185
JBrowse link
G Psmd4 proteasome 26S subunit ubiquitin receptor, non-ATPase 4 increases expression EXP bexarotene results in increased expression of PSMD4 mRNA CTD PMID:16648578 NCBI chr 2:182,598,934...182,608,250
Ensembl chr 2:182,598,934...182,608,194
JBrowse link
G Pspn persephin increases expression EXP bexarotene results in increased expression of PSPN mRNA CTD PMID:16648578 NCBI chr 9:1,841,105...1,841,663
Ensembl chr 9:1,840,896...1,854,327
JBrowse link
G Ptger3 prostaglandin E receptor 3 decreases expression ISO bexarotene results in decreased expression of PTGER3 mRNA CTD PMID:17849452 NCBI chr 2:246,606,131...246,750,970
Ensembl chr 2:246,606,183...246,684,434
JBrowse link
G Ptger4 prostaglandin E receptor 4 decreases expression ISO bexarotene results in decreased expression of PTGER4 mRNA CTD PMID:17849452 NCBI chr 2:54,330,563...54,347,451
Ensembl chr 2:54,335,424...54,346,670
JBrowse link
G Ptms parathymosin increases expression EXP bexarotene results in increased expression of PTMS mRNA CTD PMID:16648578 NCBI chr 4:157,722,384...157,726,575
Ensembl chr 4:157,722,386...157,727,009
JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C increases expression EXP bexarotene results in increased expression of PTPRC mRNA CTD PMID:16648578 NCBI chr13:49,596,193...49,708,283
Ensembl chr13:49,596,193...49,708,692
JBrowse link
G Qpct glutaminyl-peptide cyclotransferase increases expression EXP bexarotene results in increased expression of QPCT mRNA CTD PMID:16648578 NCBI chr 6:15,964,656...15,996,925
Ensembl chr 6:15,964,657...15,996,711
JBrowse link
G Rab11b RAB11B, member RAS oncogene family increases expression EXP bexarotene results in increased expression of RAB11B mRNA CTD PMID:16648578 NCBI chr 7:14,521,448...14,534,589
Ensembl chr 7:14,521,368...14,534,593
JBrowse link
G Rab7a RAB7A, member RAS oncogene family increases expression EXP bexarotene results in increased expression of RAB7 mRNA CTD PMID:16648578 NCBI chr 4:120,461,966...120,510,756
Ensembl chr 4:120,461,963...120,506,889
JBrowse link
G Rabep2 rabaptin, RAB GTPase binding effector protein 2 increases expression EXP bexarotene results in increased expression of RABEP2 mRNA CTD PMID:16648578 NCBI chr 1:181,010,305...181,026,651
Ensembl chr 1:181,010,305...181,026,648
JBrowse link
G Rarb retinoic acid receptor, beta increases expression ISO bexarotene results in increased expression of RARB mRNA CTD PMID:17178900 NCBI chr15:8,700,533...9,051,288
Ensembl chr15:8,406,492...9,051,288
JBrowse link
G Rasl11a RAS-like family 11 member A increases expression EXP bexarotene results in increased expression of RASL11A mRNA CTD PMID:16648578 NCBI chr12:8,258,148...8,262,576
Ensembl chr12:8,258,159...8,262,576
JBrowse link
G Rassf1 Ras association domain family member 1 decreases expression ISO bexarotene results in decreased expression of RASSF1 mRNA CTD PMID:17849452 NCBI chr 8:108,225,023...108,236,164
Ensembl chr 8:108,225,023...108,236,164
JBrowse link
G Rb1 RB transcriptional corepressor 1 decreases phosphorylation ISO bexarotene results in decreased phosphorylation of RB1 protein CTD PMID:16273314 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
JBrowse link
G Rdh16 retinol dehydrogenase 16 increases expression EXP bexarotene results in increased expression of RDH2 mRNA CTD PMID:16648578 NCBI chr 7:63,616,724...63,624,120
Ensembl chr 7:63,597,536...63,624,124
JBrowse link
G Renbp renin binding protein increases expression EXP bexarotene results in increased expression of RENBP mRNA CTD PMID:16648578 NCBI chr  X:151,661,463...151,670,538
Ensembl chr  X:151,661,458...151,670,516
JBrowse link
G Rest RE1-silencing transcription factor increases expression EXP bexarotene results in increased expression of REST mRNA CTD PMID:16648578 NCBI chr14:30,859,109...30,879,828
Ensembl chr14:30,862,553...30,894,354
JBrowse link
G RGD1564865 similar to 20-alpha-hydroxysteroid dehydrogenase increases expression ISO Bexarotene results in increased expression of AKR1C1 mRNA CTD PMID:17178900 NCBI chr17:65,847,580...65,881,488
Ensembl chr17:65,835,634...65,881,488
JBrowse link
G Rgn regucalcin decreases expression EXP bexarotene results in decreased expression of RGN mRNA CTD PMID:16648578 NCBI chr  X:1,619,030...1,634,456
Ensembl chr  X:1,619,032...1,634,450
JBrowse link
G Rida reactive intermediate imine deaminase A homolog decreases expression EXP bexarotene results in decreased expression of RIDA mRNA CTD PMID:16648578 NCBI chr 7:65,691,429...65,705,257
Ensembl chr 7:65,691,435...65,705,716
JBrowse link
G Rnase1 ribonuclease A family member 1, pancreatic increases expression EXP bexarotene results in increased expression of RNASE1 mRNA CTD PMID:16648578 NCBI chr15:24,361,924...24,363,658
Ensembl chr15:24,361,927...24,363,624
JBrowse link
G Rpl18a ribosomal protein L18A increases expression EXP bexarotene results in increased expression of RPL18A mRNA CTD PMID:16648578 NCBI chr16:18,542,572...18,544,578
Ensembl chr16:18,542,566...18,545,546
JBrowse link
G Rpl22 ribosomal protein L22 increases expression EXP bexarotene results in increased expression of RPL22 mRNA CTD PMID:16648578 NCBI chr 5:162,835,251...162,841,977
Ensembl chr 5:162,833,740...162,843,368
JBrowse link
G Rpl7a ribosomal protein L7a increases expression EXP bexarotene results in increased expression of RPL7A mRNA CTD PMID:16648578 NCBI chr 3:10,239,026...10,241,703
Ensembl chr 3:10,239,001...10,241,716
JBrowse link
G Rps2 ribosomal protein S2 increases expression EXP bexarotene results in increased expression of RPS2 mRNA CTD PMID:16648578 NCBI chr10:13,747,316...13,749,165
Ensembl chr10:13,747,301...13,749,163
JBrowse link
G Rpsa ribosomal protein SA increases expression EXP bexarotene results in increased expression of RPSA mRNA CTD PMID:16648578 NCBI chr 8:119,851,225...119,855,103
Ensembl chr 8:119,851,225...119,855,247
JBrowse link
G RT1-Ba RT1 class II, locus Ba multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in decreased expression of RT1-BA mRNA CTD PMID:17630414 NCBI chr20:4,575,134...4,579,727
Ensembl chr20:4,575,134...4,579,744
JBrowse link
G RT1-Cl RT1 class Ib, locus Cl increases expression EXP bexarotene results in increased expression of RT1-CL mRNA CTD PMID:16648578
G RT1-Da RT1 class II, locus Da multiple interactions
increases expression
EXP [bexarotene co-treated with Tamoxifen] results in decreased expression of RT1-DA mRNA
bexarotene results in increased expression of RT1-DA mRNA
CTD PMID:16648578 PMID:17630414 NCBI chr20:4,513,464...4,518,457
Ensembl chr20:4,512,911...4,518,455
JBrowse link
G RT1-Db1 RT1 class II, locus Db1 multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in decreased expression of RT1-DB1 mRNA CTD PMID:17630414 NCBI chr20:4,548,664...4,558,237
Ensembl chr20:4,548,666...4,558,258
JBrowse link
G RT1-EC2 RT1 class Ib, locus EC2 increases expression EXP bexarotene results in increased expression of RT1-EC2 mRNA CTD PMID:16648578
G Rtn4 reticulon 4 increases expression EXP bexarotene results in increased expression of RTN4 mRNA CTD PMID:17630414 NCBI chr14:103,450,074...103,497,687
Ensembl chr14:103,449,930...103,497,686
JBrowse link
G Rxra retinoid X receptor alpha affects binding
multiple interactions
ISO Bexarotene binds to RXRA protein
Bexarotene binds to and results in increased activity of RXRA protein; RXRA promotes the reaction [Bexarotene results in increased expression of APOA2 mRNA]; RXRA protein affects the reaction [Bexarotene results in increased expression of CYP2B6 mRNA]; RXRA protein affects the reaction [Bexarotene results in increased expression of HSD11B2 mRNA]; RXRA protein affects the reaction [Bexarotene results in increased expression of HSD11B2 protein]
CTD PMID:8668150 PMID:21218783 PMID:23843199 PMID:31312845 PMID:31566444 More... NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712
JBrowse link
G Rxrb retinoid X receptor beta affects binding ISO bexarotene binds to RXRB protein CTD PMID:23843199 NCBI chr20:4,816,813...4,823,267
Ensembl chr20:4,816,815...4,828,773
JBrowse link
G Rxrg retinoid X receptor gamma affects binding
decreases expression
ISO bexarotene binds to RXRG protein
bexarotene results in decreased expression of RXRG mRNA
CTD PMID:17849452 PMID:23843199 NCBI chr13:79,743,430...79,785,173
Ensembl chr13:79,743,563...79,785,167
JBrowse link
G S100a10 S100 calcium binding protein A10 decreases expression EXP bexarotene results in decreased expression of S100A10 mRNA CTD PMID:16648578 NCBI chr 2:179,221,012...179,229,659
Ensembl chr 2:179,220,887...179,229,661
JBrowse link
G S100a9 S100 calcium binding protein A9 increases expression ISO
EXP
bexarotene results in increased expression of S100A9 mRNA CTD PMID:16648578 PMID:17178900 NCBI chr 2:176,190,361...176,193,182
Ensembl chr 2:176,190,361...176,193,230
JBrowse link
G S100b S100 calcium binding protein B decreases expression EXP bexarotene results in decreased expression of S100B mRNA CTD PMID:16648578 NCBI chr20:12,372,866...12,381,619
Ensembl chr20:12,372,881...12,394,743
JBrowse link
G Scd stearoyl-CoA desaturase increases expression
multiple interactions
ISO
EXP
bexarotene results in increased expression of SCD1 mRNA
[Bexarotene co-treated with GW 3965] results in increased expression of SCD mRNA; [Bexarotene co-treated with TO-901317] results in increased expression of SCD mRNA
[Tamoxifen co-treated with bexarotene] results in increased expression of SCD1 mRNA
Bexarotene results in increased expression of SCD mRNA
CTD PMID:17178900 PMID:17630414 PMID:23292798 PMID:32123961 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
JBrowse link
G Scd2 stearoyl-Coenzyme A desaturase 2 increases expression EXP bexarotene results in increased expression of SCD2 mRNA CTD PMID:16648578 PMID:17630414 NCBI chr 1:243,169,171...243,182,231
Ensembl chr 1:243,169,236...243,182,232
JBrowse link
G Scp2 sterol carrier protein 2 decreases expression EXP bexarotene results in decreased expression of SCP2 mRNA CTD PMID:16648578 NCBI chr 5:122,806,949...122,881,259
Ensembl chr 5:122,776,549...122,881,287
JBrowse link
G Sdc2 syndecan 2 decreases expression EXP bexarotene results in decreased expression of SDC2 mRNA CTD PMID:16648578 NCBI chr 7:64,127,185...64,239,885
Ensembl chr 7:64,127,110...64,241,081
JBrowse link
G Serpina1 serpin family A member 1 decreases expression EXP bexarotene results in decreased expression of SERPINA1 mRNA CTD PMID:16648578 NCBI chr 6:122,866,314...122,888,339
Ensembl chr 6:122,866,312...122,888,339
JBrowse link
G Serpina3n serine (or cysteine) peptidase inhibitor, clade A, member 3N decreases expression EXP bexarotene results in decreased expression of SERPINA3N mRNA CTD PMID:16648578 NCBI chr 6:123,323,632...123,331,166 JBrowse link
G Serpind1 serpin family D member 1 decreases expression EXP bexarotene results in decreased expression of SERPIND1 mRNA CTD PMID:16648578 NCBI chr11:83,664,517...83,675,593
Ensembl chr11:83,664,518...83,675,519
JBrowse link
G Serpinh1 serpin family H member 1 increases expression EXP bexarotene results in increased expression of SERPINH1 mRNA CTD PMID:17630414 NCBI chr 1:153,643,500...153,650,853
Ensembl chr 1:153,643,510...153,650,801
JBrowse link
G Sfpq splicing factor proline and glutamine rich decreases expression EXP bexarotene results in decreased expression of SFPQ mRNA CTD PMID:16648578 NCBI chr 5:139,338,034...139,353,476
Ensembl chr 5:139,338,075...139,353,472
JBrowse link
G Shh sonic hedgehog signaling molecule increases expression ISO bexarotene results in increased expression of SHH mRNA CTD PMID:26096596 NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170
JBrowse link
G Siah2 siah E3 ubiquitin protein ligase 2 decreases expression ISO bexarotene results in decreased expression of SIAH2 mRNA CTD PMID:17178900 NCBI chr 2:142,913,924...142,931,752
Ensembl chr 2:142,914,003...142,931,950
JBrowse link
G Slc1a3 solute carrier family 1 member 3 decreases expression EXP bexarotene results in decreased expression of SLC1A3 mRNA CTD PMID:16648578 NCBI chr 2:57,755,495...57,830,605
Ensembl chr 2:57,755,497...57,830,605
JBrowse link
G Slc27a1 solute carrier family 27 member 1 increases expression
multiple interactions
EXP
ISO
bexarotene results in increased expression of SLC27A1 mRNA
[[Dexamethasone co-treated with INS protein co-treated with 1-Methyl-3-isobutylxanthine] co-treated with bexarotene] results in increased expression of SLC27A1 mRNA
CTD PMID:10777552 NCBI chr16:18,278,984...18,300,173
Ensembl chr16:18,278,984...18,296,063
JBrowse link
G Slc27a2 solute carrier family 27 member 2 decreases expression EXP bexarotene results in decreased expression of SLC27A2 mRNA CTD PMID:16648578 NCBI chr 3:113,804,728...113,842,208
Ensembl chr 3:113,804,728...113,842,208
JBrowse link
G Slc2a2 solute carrier family 2 member 2 increases expression EXP bexarotene results in increased expression of SLC2A2 mRNA CTD PMID:16648578 NCBI chr 2:111,609,798...111,639,930
Ensembl chr 2:111,611,774...111,639,933
JBrowse link
G Slc2a4 solute carrier family 2 member 4 multiple interactions ISO [bexarotene co-treated with rosiglitazone] results in increased expression of SLC2A4 mRNA CTD PMID:10548525 NCBI chr10:54,666,015...54,671,581
Ensembl chr10:54,666,015...54,671,565
JBrowse link
G Slc35b1 solute carrier family 35, member B1 increases expression EXP bexarotene results in increased expression of SLC35B1 mRNA CTD PMID:16648578 NCBI chr10:80,327,921...80,335,279
Ensembl chr10:80,327,945...80,335,274
JBrowse link
G Slc6a6 solute carrier family 6 member 6 increases expression EXP bexarotene results in increased expression of SLC6A6 mRNA CTD PMID:16648578 NCBI chr 4:124,195,186...124,268,880
Ensembl chr 4:124,195,218...124,268,875
JBrowse link
G Slc7a1 solute carrier family 7 member 1 decreases expression ISO bexarotene results in decreased expression of SLC7A1 mRNA CTD PMID:17178900 NCBI chr12:6,628,214...6,703,849
Ensembl chr12:6,628,007...6,703,849
JBrowse link
G Slc7a5 solute carrier family 7 member 5 decreases expression ISO bexarotene results in decreased expression of SLC7A5 mRNA CTD PMID:17178900 NCBI chr19:49,935,220...49,963,823
Ensembl chr19:49,935,220...49,963,823
JBrowse link
G Smad5 SMAD family member 5 increases expression ISO bexarotene results in increased expression of SMAD5 mRNA CTD PMID:17178900 NCBI chr17:7,862,332...7,891,678
Ensembl chr17:7,864,720...7,891,634
JBrowse link
G Sncg synuclein, gamma decreases expression EXP bexarotene results in decreased expression of SNCG mRNA CTD PMID:16648578 NCBI chr16:9,700,513...9,705,751
Ensembl chr16:9,700,514...9,705,368
JBrowse link
G Snd1 staphylococcal nuclease and tudor domain containing 1 increases expression EXP bexarotene results in increased expression of SND1 mRNA CTD PMID:16648578 NCBI chr 4:57,095,205...57,494,501
Ensembl chr 4:57,095,208...57,530,843
JBrowse link
G Snn stannin decreases expression EXP bexarotene results in decreased expression of SNN mRNA CTD PMID:16648578 NCBI chr10:4,572,933...4,581,606
Ensembl chr10:4,572,376...4,584,021
JBrowse link
G Sord sorbitol dehydrogenase decreases expression EXP bexarotene results in decreased expression of SORD mRNA CTD PMID:16648578 NCBI chr 3:109,184,697...109,216,133
Ensembl chr 3:109,184,676...109,216,133
JBrowse link
G Sorl1 sortilin related receptor 1 multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in increased expression of SORL1 mRNA CTD PMID:17630414 NCBI chr 8:42,341,704...42,504,435
Ensembl chr 8:42,341,704...42,504,513
JBrowse link
G Sp7 Sp7 transcription factor decreases expression
multiple interactions
ISO bexarotene results in decreased expression of SP7 mRNA
bexarotene inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA]
CTD PMID:25932594 NCBI chr 7:133,484,609...133,494,788
Ensembl chr 7:133,484,609...133,494,847
JBrowse link
G Sparc secreted protein acidic and cysteine rich increases expression ISO bexarotene results in increased expression of SPARC mRNA CTD PMID:17178900 NCBI chr10:39,516,394...39,538,252
Ensembl chr10:39,516,406...39,538,396
JBrowse link
G Spink1 serine peptidase inhibitor, Kazal type 1 multiple interactions
increases expression
EXP [bexarotene co-treated with Tamoxifen] results in increased expression of SPINK1 mRNA
bexarotene results in increased expression of SPINK1 mRNA
CTD PMID:16648578 PMID:17630414 NCBI chr18:35,870,723...35,882,693
Ensembl chr18:35,824,550...35,882,642
JBrowse link
G Spp1 secreted phosphoprotein 1 decreases expression EXP bexarotene results in decreased expression of SPP1 mRNA CTD PMID:16648578 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162
JBrowse link
G Spp2 secreted phosphoprotein 2 decreases expression EXP bexarotene results in decreased expression of SPP2 mRNA CTD PMID:16648578 NCBI chr 9:89,006,858...89,026,676
Ensembl chr 9:89,007,175...89,026,688
JBrowse link
G Spt1 salivary protein 1 decreases expression EXP bexarotene results in decreased expression of SPT1 mRNA CTD PMID:16648578 NCBI chr 7:134,914,177...134,924,215
Ensembl chr 7:134,914,177...134,924,157
JBrowse link
G Sqstm1 sequestosome 1 increases expression EXP bexarotene results in increased expression of SQSTM1 mRNA CTD PMID:16648578 NCBI chr10:34,525,517...34,536,685
Ensembl chr10:34,525,519...34,536,673
JBrowse link
G Srd5a1 steroid 5 alpha-reductase 1 decreases expression EXP bexarotene results in decreased expression of SRD5A1 mRNA CTD PMID:16648578 NCBI chr 1:33,686,069...33,720,468
Ensembl chr 1:33,686,391...33,720,461
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 increases expression
multiple interactions
EXP
ISO
bexarotene results in increased expression of SREBF1 mRNA
Bexarotene results in increased expression of SREBF1 mRNA
[Bexarotene co-treated with GW 3965] results in increased expression of SREBF1 mRNA; [Bexarotene co-treated with paxilline] results in increased expression of SREBF1 mRNA; [Bexarotene co-treated with TO-901317] results in increased expression of SREBF1 mRNA; Bexarotene promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SREBF1 mRNA]
CTD PMID:23292798 PMID:25932594 PMID:32123961 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
JBrowse link
G Srsf2 serine and arginine rich splicing factor 2 decreases expression ISO bexarotene results in decreased expression of SRSF2 mRNA CTD PMID:17178900 NCBI chr10:102,052,158...102,055,365
Ensembl chr10:102,052,314...102,055,338
JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 decreases expression EXP bexarotene results in decreased expression of SULT1A1 mRNA CTD PMID:16648578 NCBI chr 1:181,272,022...181,276,750
Ensembl chr 1:181,272,023...181,275,562
JBrowse link
G Sult1b1 sulfotransferase family 1B member 1 decreases expression EXP bexarotene results in decreased expression of SULT1B1 mRNA CTD PMID:16648578 NCBI chr14:20,492,763...20,505,491
Ensembl chr14:20,492,708...20,505,483
JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 decreases expression EXP bexarotene results in decreased expression of SULT2A1 mRNA CTD PMID:16648578 NCBI chr 1:75,451,178...75,508,142 JBrowse link
G Tacr2 tachykinin receptor 2 increases expression EXP bexarotene results in increased expression of TACR2 mRNA CTD PMID:16648578 NCBI chr20:30,208,907...30,223,446
Ensembl chr20:30,208,907...30,223,446
JBrowse link
G Tecr trans-2,3-enoyl-CoA reductase increases expression EXP bexarotene results in increased expression of TECR mRNA CTD PMID:16648578 NCBI chr19:24,526,705...24,568,168
Ensembl chr19:24,541,615...24,568,168
JBrowse link
G Tex49 testis expressed 49 multiple interactions EXP [bexarotene co-treated with Tamoxifen] results in increased expression of TEX49 mRNA CTD PMID:17630414 NCBI chr 7:129,720,950...129,742,485
Ensembl chr 7:129,720,950...129,742,485
JBrowse link
G Tf transferrin increases expression EXP bexarotene results in increased expression of TF mRNA CTD PMID:16648578 NCBI chr 8:103,789,780...103,816,487
Ensembl chr 8:103,767,995...103,816,511
JBrowse link
G Tg thyroglobulin increases expression EXP bexarotene results in increased expression of TG mRNA CTD PMID:16648578 NCBI chr 7:98,418,293...98,603,210
Ensembl chr 7:98,418,293...98,603,210
JBrowse link
G Tgfb3 transforming growth factor, beta 3 increases expression EXP bexarotene results in increased expression of TGFB3 mRNA CTD PMID:16648578 NCBI chr 6:105,704,058...105,726,661
Ensembl chr 6:105,704,236...105,726,564
JBrowse link
G Tgm1 transglutaminase 1 decreases expression ISO bexarotene results in decreased expression of TGM1 mRNA CTD PMID:8853895 NCBI chr15:29,191,039...29,206,000
Ensembl chr15:29,191,041...29,204,523
JBrowse link
G Tgm2 transglutaminase 2 increases expression
multiple interactions
ISO bexarotene results in increased expression of TGM2 mRNA
diazepinylbenzoic acid inhibits the reaction [bexarotene results in increased expression of TGM2 mRNA]
CTD PMID:17178900 PMID:21622945 PMID:25932594 NCBI chr 3:146,772,684...146,801,924
Ensembl chr 3:146,772,687...146,801,981
JBrowse link
G Thra thyroid hormone receptor alpha multiple interactions ISO bexarotene binds to and results in decreased activity of THRA protein CTD PMID:25752796 NCBI chr10:83,701,885...83,729,408
Ensembl chr10:83,700,755...83,729,936
JBrowse link
G Tm4sf1 transmembrane 4 L six family member 1 increases expression ISO bexarotene results in increased expression of TM4SF1 mRNA CTD PMID:17178900 NCBI chr 2:141,456,950...141,466,146
Ensembl chr 2:141,453,310...141,466,146
JBrowse link
G Tmed2 transmembrane p24 trafficking protein 2 increases expression EXP bexarotene results in increased expression of TMED2 mRNA CTD PMID:16648578 NCBI chr12:32,052,542...32,061,596
Ensembl chr12:32,052,543...32,071,903
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A increases expression EXP bexarotene results in increased expression of TNFRSF1A mRNA CTD PMID:16648578 NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591
JBrowse link
G Tns1 tensin 1 increases expression EXP bexarotene results in increased expression of TNS1 mRNA CTD PMID:16648578 NCBI chr 9:75,491,886...75,702,853
Ensembl chr 9:75,495,814...75,703,225
JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO bexarotene results in increased phosphorylation of and results in increased activity of TP53 protein CTD PMID:19067706 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Tp73 tumor protein p73 increases expression ISO bexarotene results in increased expression of TP73 protein CTD PMID:19067706 NCBI chr 5:164,621,377...164,703,958
Ensembl chr 5:164,621,377...164,681,128
JBrowse link
G Tpm1 tropomyosin 1 increases expression EXP bexarotene results in increased expression of TPM1 mRNA CTD PMID:16648578 NCBI chr 8:67,635,479...67,662,330
Ensembl chr 8:67,635,479...67,662,802
JBrowse link
G Tpm3 tropomyosin 3 increases expression EXP bexarotene results in increased expression of TPM3 mRNA CTD PMID:16648578 NCBI chr 2:175,517,198...175,545,014
Ensembl chr 2:175,517,226...175,545,013
JBrowse link
G Tpm4 tropomyosin 4 increases expression EXP bexarotene results in increased expression of TPM4 mRNA CTD PMID:16648578 NCBI chr16:17,684,415...17,698,456
Ensembl chr16:17,683,195...17,705,984
JBrowse link
G Tsc22d3 TSC22 domain family, member 3 increases expression ISO bexarotene results in increased expression of TSC22D3 mRNA CTD PMID:17178900 NCBI chr  X:104,217,898...104,277,935
Ensembl chr  X:104,217,925...104,276,861
JBrowse link
G Ttr transthyretin decreases expression EXP bexarotene results in decreased expression of TTR mRNA CTD PMID:16648578 NCBI chr18:11,941,791...11,951,008
Ensembl chr18:11,943,789...11,951,008
JBrowse link
G Tuba1a tubulin, alpha 1A increases expression EXP bexarotene results in increased expression of TUBA1A mRNA CTD PMID:16648578 NCBI chr 7:130,113,214...130,116,880 JBrowse link
G Uap1 UDP-N-acetylglucosamine pyrophosphorylase 1 decreases expression ISO bexarotene results in decreased expression of UAP1 mRNA CTD PMID:17178900 NCBI chr13:82,342,946...82,377,558
Ensembl chr13:82,342,946...82,377,469
JBrowse link
G Ucp2 uncoupling protein 2 multiple interactions ISO bexarotene promotes the reaction [rosiglitazone results in increased expression of UCP2 mRNA] CTD PMID:10548525 NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611
JBrowse link
G Ugt2b UDP glycosyltransferase 2 family, polypeptide B decreases expression EXP bexarotene results in decreased expression of UGT2B mRNA CTD PMID:16648578 NCBI chr14:20,630,572...20,665,062
Ensembl chr14:20,630,250...20,651,776
JBrowse link
G Vamp8 vesicle-associated membrane protein 8 increases expression ISO bexarotene results in increased expression of VAMP8 mRNA CTD PMID:17178900 NCBI chr 4:104,442,383...104,452,884
Ensembl chr 4:104,442,393...104,452,897
JBrowse link
G Vegfa vascular endothelial growth factor A increases expression EXP bexarotene results in increased expression of VEGFA mRNA CTD PMID:16648578 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
G Xbp1 X-box binding protein 1 decreases expression ISO bexarotene results in decreased expression of XBP1 mRNA CTD PMID:17178900 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693
JBrowse link
G Ywhah tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta decreases expression EXP bexarotene results in decreased expression of YWHAH mRNA CTD PMID:16648578 NCBI chr14:77,696,332...77,705,715
Ensembl chr14:77,696,333...77,705,741
JBrowse link
G Zbtb16 zinc finger and BTB domain containing 16 increases expression EXP bexarotene results in increased expression of ZBTB16 mRNA CTD PMID:23292798 NCBI chr 8:48,989,376...49,177,011
Ensembl chr 8:48,994,566...49,177,011
JBrowse link
G Zp3 zona pellucida glycoprotein 3 increases expression EXP bexarotene results in increased expression of ZP3 mRNA CTD PMID:16648578 NCBI chr12:20,690,547...20,697,513
Ensembl chr12:20,690,547...20,697,513
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19812
    role 19761
      application 19471
        pharmaceutical 19319
          drug 19319
            antineoplastic agent 17316
              bexarotene 465
Path 2
Term Annotations click to browse term
  CHEBI ontology 19812
    subatomic particle 19811
      composite particle 19811
        hadron 19811
          baryon 19811
            nucleon 19811
              atomic nucleus 19811
                atom 19811
                  main group element atom 19708
                    p-block element atom 19708
                      carbon group element atom 19630
                        carbon atom 19620
                          organic molecular entity 19620
                            organic group 18728
                              organic divalent group 18719
                                organodiyl group 18719
                                  carbonyl group 18667
                                    carbonyl compound 18667
                                      carboxylic acid 18364
                                        aromatic carboxylic acid 11708
                                          benzoic acids 11681
                                            bexarotene 465
paths to the root