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ONTOLOGY REPORT - ANNOTATIONS


Term:loxapine
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Accession:CHEBI:50841 term browser browse the term
Definition:A dibenzooxazepine that has formula C18H18ClN3O.
Synonyms:exact_synonym: 2-chloro-11-(4-methylpiperazin-1-yl)dibenzo[b,f][1,4]oxazepine
 related_synonym: 2-chloro-11-(4-methyl-1-piperazinyl)dibenz[b,f][1,4]oxazepine;   Cloxazepine;   Formula=C18H18ClN3O;   InChI=1S/C18H18ClN3O/c1-21-8-10-22(11-9-21)18-14-12-13(19)6-7-16(14)23-17-5-3-2-4-15(17)20-18/h2-7,12H,8-11H2,1H3;   InChIKey=XJGVXQDUIWGIRW-UHFFFAOYSA-N;   SMILES=CN1CCN(CC1)C1=Nc2ccccc2Oc2ccc(Cl)cc12;   loxapina;   loxapinum;   oxilapine
 alt_id: CHEBI:50839;   CHEBI:6548
 xref: Beilstein:626753 "Beilstein";   CAS:1977-10-2 "ChemIDplus";   CAS:1977-10-2 "KEGG COMPOUND";   CAS:1977-10-2 "NIST Chemistry WebBook";   DrugBank:DB00408;   Drug_Central:1613 "DrugCentral";   KEGG:C07104;   KEGG:D02340;   LINCS:LSM-2881
 xref_mesh: MESH:D008152
 xref: Patent:NL6406089;   Patent:US3412193;   Patent:US3546226;   Wikipedia:Loxapine


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loxapine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 JBrowse link 8 62,451,360 62,458,244 RGD:6480464
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 JBrowse link 7 123,599,264 123,608,436 RGD:6480464
G Drd1 dopamine receptor D1 JBrowse link 17 11,099,736 11,104,352 RGD:6480464
G Drd2 dopamine receptor D2 JBrowse link 8 53,678,777 53,743,643 RGD:6480464
G Htr1a 5-hydroxytryptamine receptor 1A JBrowse link 2 36,246,628 36,247,896 RGD:6480464
G Htr2a 5-hydroxytryptamine receptor 2A JBrowse link 15 56,666,152 56,732,469 RGD:6480464
G Htr2c 5-hydroxytryptamine receptor 2C JBrowse link X 118,084,520 118,318,040 RGD:6480464
G Kcnh2 potassium voltage-gated channel subfamily H member 2 JBrowse link 4 7,355,066 7,387,282 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19716
    role 19663
      biological role 19661
        pharmacological role 18755
          neurotransmitter agent 16393
            dopaminergic agent 5041
              dopaminergic antagonist 1166
                loxapine 8
                  loxapine succinate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19716
    subatomic particle 19712
      composite particle 19712
        hadron 19712
          baryon 19712
            nucleon 19712
              atomic nucleus 19712
                atom 19712
                  main group element atom 19598
                    p-block element atom 19598
                      carbon group element atom 19486
                        carbon atom 19480
                          organic molecular entity 19480
                            organic molecule 19402
                              organic cyclic compound 19158
                                organic heterocyclic compound 18245
                                  organic heteropolycyclic compound 17500
                                    organic heterotricyclic compound 13738
                                      dibenzooxazepine 20
                                        loxapine 8
                                          loxapine succinate 0
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