CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: appetite regulator
Accession: CHEBI:50780
browse the term
Definition: An agent which regulates the physiologic mechanisms that control the appetite and food intake.
Synonyms: related_synonym: appetite regulators
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Slc22a2
solute carrier family 22 member 2
multiple interactions
ISO
Dexfenfluramine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium]
CTD
PMID:21599003
NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268
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Slc6a4
solute carrier family 6 member 4
affects activity
ISO
Dexfenfluramine affects the activity of SLC6A4 protein
CTD
PMID:18506000
NCBI chr10:61,824,208...61,858,924
Ensembl chr10:61,826,123...61,858,384
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Cyp2b3
cytochrome P450, family 2, subfamily b, polypeptide 3
increases metabolic processing
ISO
CYP2B6 protein results in increased metabolism of Benzphetamine
CTD
PMID:12464242 PMID:15769884
NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
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Cyp3a2
cytochrome P450, family 3, subfamily a, polypeptide 2
multiple interactions
ISO
Benzphetamine inhibits the reaction [CYP3A4 protein results in increased oxidation of 7-benzyloxy-4-trifluoromethylcoumarin]
CTD
PMID:19299527
NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
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Acox1
acyl-CoA oxidase 1
increases expression
ISO
cannabigerol results in increased expression of ACOX1 mRNA
CTD
PMID:30611848
NCBI chr10:101,406,197...101,431,252
Ensembl chr10:101,406,197...101,431,232
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Adcy5
adenylate cyclase 5
increases expression
ISO
cannabigerol results in increased expression of ADCY5 mRNA
CTD
PMID:33019509
NCBI chr11:65,471,612...65,618,877
Ensembl chr11:65,471,612...65,618,974
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Adcy9
adenylate cyclase 9
decreases expression
ISO
cannabigerol results in decreased expression of ADCY9 mRNA
CTD
PMID:33019509
NCBI chr10:11,138,966...11,262,067
Ensembl chr10:11,139,446...11,262,066
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Akt1
AKT serine/threonine kinase 1
increases expression
ISO
cannabigerol results in increased expression of AKT1 mRNA
CTD
PMID:33019509
NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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Atf4
activating transcription factor 4
increases expression
ISO
cannabigerol results in increased expression of ATF4 mRNA
CTD
PMID:33019509
NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
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Bcl2l1
Bcl2-like 1
increases expression
ISO
cannabigerol results in increased expression of BCL2L1 mRNA
CTD
PMID:33019509
NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
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Camk2b
calcium/calmodulin-dependent protein kinase II beta
decreases expression
ISO
cannabigerol results in decreased expression of CAMK2B mRNA
CTD
PMID:33019509
NCBI chr14:80,845,206...80,934,172
Ensembl chr14:80,845,238...80,933,994
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Casp8
caspase 8
decreases expression
ISO
cannabigerol results in decreased expression of CASP8 mRNA
CTD
PMID:33019509
NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
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Ccl3
C-C motif chemokine ligand 3
multiple interactions
EXP
cannabigerol inhibits the reaction [Lipopolysaccharides results in increased secretion of CCL3 protein]
CTD
PMID:22971837
NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
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Clock
clock circadian regulator
decreases expression
ISO
cannabigerol results in decreased expression of CLOCK mRNA
CTD
PMID:33019509
NCBI chr14:31,908,542...31,992,673
Ensembl chr14:31,908,566...31,990,400
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Cnr2
cannabinoid receptor 2
multiple interactions
ISO
cannabigerol affects the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to CNR2 protein]
CTD
PMID:22971837
NCBI chr 5:148,125,222...148,151,548
Ensembl chr 5:148,125,604...148,151,548
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Cpt1a
carnitine palmitoyltransferase 1A
increases expression
ISO
cannabigerol results in increased expression of CPT1A mRNA
CTD
PMID:30611848
NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
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Creb1
cAMP responsive element binding protein 1
decreases expression
ISO
cannabigerol results in decreased expression of CREB1 mRNA
CTD
PMID:33019509
NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
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Cyp2j4
cytochrome P450, family 2, subfamily j, polypeptide 4
increases metabolic processing multiple interactions
ISO
CYP2J2 protein results in increased metabolism of cannabigerol cannabigerol inhibits the reaction [CYP2J2 protein results in increased metabolism of anandamide]
CTD
PMID:29689453
NCBI chr 5:111,179,981...111,207,490
Ensembl chr 5:111,178,703...111,244,794
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Dlgap1
DLG associated protein 1
increases expression
ISO
cannabigerol results in increased expression of DLGAP1 mRNA
CTD
PMID:33019509
NCBI chr 9:109,857,500...110,726,817
Ensembl chr 9:110,167,448...110,726,817
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Drd2
dopamine receptor D2
decreases expression
ISO
cannabigerol results in decreased expression of DRD2 mRNA
CTD
PMID:33019509
NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875
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Eif2ak3
eukaryotic translation initiation factor 2 alpha kinase 3
decreases expression
ISO
cannabigerol results in decreased expression of EIF2AK3 mRNA
CTD
PMID:33019509
NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
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Ern1
endoplasmic reticulum to nucleus signaling 1
decreases expression
ISO
cannabigerol results in decreased expression of ERN1 mRNA
CTD
PMID:33019509
NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029
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Fabp4
fatty acid binding protein 4
multiple interactions increases expression
ISO
cannabigerol promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of FABP4 mRNA] cannabigerol results in increased expression of FABP4 mRNA
CTD
PMID:30611848
NCBI chr 2:91,580,879...91,585,567
Ensembl chr 2:91,580,885...91,585,578
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Gnai2
G protein subunit alpha i2
increases expression
ISO
cannabigerol results in increased expression of GNAI2 mRNA
CTD
PMID:33019509
NCBI chr 8:108,288,401...108,309,009
Ensembl chr 8:108,288,401...108,308,979
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Gnal
G protein subunit alpha L
decreases expression
ISO
cannabigerol results in decreased expression of GNAL mRNA
CTD
PMID:33019509
NCBI chr18:60,622,311...60,762,599
Ensembl chr18:60,622,311...60,762,599
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Gnb4
G protein subunit beta 4
increases expression
ISO
cannabigerol results in increased expression of GNB4 mRNA
CTD
PMID:33019509
NCBI chr 2:115,360,746...115,400,680
Ensembl chr 2:115,364,918...115,400,579
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Gpt
glutamic--pyruvic transaminase
decreases activity
EXP
cannabigerol results in decreased activity of GPT protein
CTD
PMID:36796712
NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
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Hap1
huntingtin-associated protein 1
increases expression
ISO
cannabigerol results in increased expression of HAP1 mRNA
CTD
PMID:33019509
NCBI chr10:85,277,890...85,286,126
Ensembl chr10:85,277,890...85,286,126
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Il1b
interleukin 1 beta
multiple interactions
EXP
cannabigerol inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]
CTD
PMID:22971837
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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Il6
interleukin 6
multiple interactions
EXP
cannabigerol inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]
CTD
PMID:22971837
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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Ins2
insulin 2
multiple interactions
ISO
cannabigerol promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of FABP4 mRNA]; cannabigerol promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of PPARG mRNA]
CTD
PMID:30611848
NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
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Map3k5
mitogen-activated protein kinase kinase kinase 5
decreases expression
ISO
cannabigerol results in decreased expression of MAP3K5 mRNA
CTD
PMID:33019509
NCBI chr 1:14,685,776...14,904,935
Ensembl chr 1:14,685,492...14,904,800
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Npy
neuropeptide Y
decreases expression
EXP
cannabigerol results in decreased expression of NPY mRNA
CTD
PMID:31941059
NCBI chr 4:78,881,294...78,888,495
Ensembl chr 4:78,881,264...78,888,495
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Parp4
poly (ADP-ribose) polymerase family, member 4
decreases expression
ISO
cannabigerol results in decreased expression of PARP4 mRNA
CTD
PMID:33019509
NCBI chr15:30,690,503...30,792,868
Ensembl chr15:30,686,613...30,828,810
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Pld1
phospholipase D1
decreases expression
ISO
cannabigerol results in decreased expression of PLD1 mRNA
CTD
PMID:33019509
NCBI chr 2:110,849,205...111,047,304
Ensembl chr 2:110,893,608...111,047,692
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Pomc
proopiomelanocortin
decreases expression
EXP
cannabigerol results in decreased expression of POMC mRNA
CTD
PMID:31941059
NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664
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Ppara
peroxisome proliferator activated receptor alpha
multiple interactions
ISO
cannabigerol binds to and results in increased activity of PPARA protein
CTD
PMID:30611848
NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
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Pparg
peroxisome proliferator-activated receptor gamma
decreases expression multiple interactions increases expression
ISO
cannabigerol results in decreased expression of PPARG protein cannabigerol binds to and results in increased activity of PPARG protein; cannabigerol promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of PPARG mRNA] cannabigerol results in increased expression of PPARG mRNA
CTD
PMID:28853159 PMID:30611848
NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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Ppp3r1
protein phosphatase 3, regulatory subunit B, alpha
decreases expression
ISO
cannabigerol results in decreased expression of PPP3R1 mRNA
CTD
PMID:33019509
NCBI chr14:91,556,743...91,606,391
Ensembl chr14:91,604,121...91,606,907
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Prkca
protein kinase C, alpha
increases expression
ISO
cannabigerol results in increased expression of PRKCA mRNA
CTD
PMID:33019509
NCBI chr10:92,889,390...93,288,013
Ensembl chr10:92,894,012...93,288,012
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Prkcb
protein kinase C, beta
decreases expression
ISO
cannabigerol results in decreased expression of PRKCB mRNA
CTD
PMID:33019509
NCBI chr 1:176,832,173...177,163,539
Ensembl chr 1:176,832,226...177,163,536
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Shank1
SH3 and multiple ankyrin repeat domains 1
decreases expression
ISO
cannabigerol results in decreased expression of SHANK1 mRNA
CTD
PMID:33019509
NCBI chr 1:94,807,879...94,857,356
Ensembl chr 1:94,808,276...94,855,824
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Slc18a1
solute carrier family 18 member A1
decreases expression
ISO
cannabigerol results in decreased expression of SLC18A1 mRNA
CTD
PMID:33019509
NCBI chr16:20,653,268...20,687,051
Ensembl chr16:20,653,508...20,687,051
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Slc1a2
solute carrier family 1 member 2
decreases expression
ISO
cannabigerol results in decreased expression of SLC1A2 mRNA
CTD
PMID:33019509
NCBI chr 3:89,005,129...89,135,469
Ensembl chr 3:89,005,129...89,126,498
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Slc32a1
solute carrier family 32 member 1
increases expression
ISO
cannabigerol results in increased expression of SLC32A1 mRNA
CTD
PMID:33019509
NCBI chr 3:147,267,373...147,271,842
Ensembl chr 3:147,267,373...147,271,844
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Slc38a1
solute carrier family 38, member 1
decreases expression
ISO
cannabigerol results in decreased expression of SLC38A1 mRNA
CTD
PMID:33019509
NCBI chr 7:127,733,230...127,802,541
Ensembl chr 7:127,738,226...127,802,218
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Tnf
tumor necrosis factor
multiple interactions
EXP
cannabigerol inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]
CTD
PMID:22971837
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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Trpv1
transient receptor potential cation channel, subfamily V, member 1
multiple interactions increases activity
ISO
[cannabigerol results in increased activity of TRPV1 protein] which results in increased uptake of Calcium
CTD
PMID:31096838
NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513
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Bmpr2
bone morphogenetic protein receptor type 2
increases response to substance
ISO
BMPR2 gene mutant form results in increased susceptibility to Fenfluramine
CTD
PMID:12358323
NCBI chr 9:61,192,718...61,307,280
Ensembl chr 9:61,190,566...61,301,809
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Fos
Fos proto-oncogene, AP-1 transcription factor subunit
multiple interactions increases expression
EXP
Fluoxetine inhibits the reaction [Fenfluramine results in increased expression of FOS protein]; N-chlorophenylalanine inhibits the reaction [Fenfluramine results in increased expression of FOS protein]
CTD
PMID:9452197
NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
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Htr2a
5-hydroxytryptamine receptor 2A
affects binding
ISO
Fenfluramine binds to HTR2A protein
CTD
PMID:10617681
NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928
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Htr2b
5-hydroxytryptamine receptor 2B
increases response to substance affects binding
ISO
HTR2B gene mutant form results in increased susceptibility to Fenfluramine Fenfluramine binds to HTR2B protein
CTD
PMID:10617681 PMID:14659797
NCBI chr 9:86,735,793...86,756,638
Ensembl chr 9:86,742,102...86,755,108
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Htr2c
5-hydroxytryptamine receptor 2C
affects binding
ISO
Fenfluramine binds to HTR2C protein
CTD
PMID:10617681
NCBI chr X:110,640,777...110,870,288
Ensembl chr X:110,641,153...110,870,287
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Prl
prolactin
multiple interactions increases expression increases secretion
ISO EXP
Cocaine affects the reaction [Fenfluramine results in increased expression of PRL protein] Clonidine inhibits the reaction [Fenfluramine results in increased secretion of PRL protein]; talipexole inhibits the reaction [Fenfluramine results in increased secretion of PRL protein]
CTD
PMID:1678730 PMID:9232209 PMID:9330023 PMID:9598218 PMID:10349036
NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062
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Cnr1
cannabinoid receptor 1
multiple interactions
EXP
Ghrelin inhibits the reaction [[Fructose co-treated with Streptozocin] results in decreased expression of CNR1 mRNA]
CTD
PMID:31468622
NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099
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Glp1r
glucagon-like peptide 1 receptor
multiple interactions
EXP
Ghrelin inhibits the reaction [[Fructose co-treated with Streptozocin] results in decreased expression of GLP1R mRNA]
CTD
PMID:31468622
NCBI chr20:8,972,004...9,010,241
Ensembl chr20:8,972,004...9,010,241
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Il1b
interleukin 1 beta
multiple interactions
ISO
ghrelin inhibits the reaction [High fat diet increases expression of IL1b mRNA in heart]
RGD
PMID:32084395
RGD:242905211
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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Il6
interleukin 6
multiple interactions
ISO
ghrelin inhibits the reaction [High fat diet increases expression of Il6 mRNA in heart]
RGD
PMID:32084395
RGD:242905211
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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Mir33
microRNA 33
multiple interactions
EXP
Ghrelin inhibits the reaction [[Fructose co-treated with Streptozocin] results in increased expression of MIR33A mRNA]
CTD
PMID:31468622
NCBI chr 7:113,713,855...113,713,923
Ensembl chr 7:113,713,855...113,713,923
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Tgfb1
transforming growth factor, beta 1
multiple interactions
ISO
ghrelin inhibits the reaction [High fat diet increases expression of Tgfb1 mRNA in heart]
RGD
PMID:32084395
RGD:242905211
NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
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Tnf
tumor necrosis factor
multiple interactions
ISO
ghrelin inhibits the reaction [high fat diet increases expression of TNF mRNA in heart]
RGD
PMID:32084395
RGD:242905211
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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Ugt1a6
UDP glucuronosyltransferase family 1 member A6
multiple interactions
ISO
UGT1A6 protein results in increased carbamoylation of and results in increased glucuronidation of lorcaserin
CTD
PMID:22259019
NCBI chr 9:88,747,213...88,808,465
Ensembl chr 9:88,713,184...88,808,465
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Ugt1a9
UDP glucuronosyltransferase family 1 member A9
multiple interactions
ISO
UGT1A9 protein results in increased carbamoylation of and results in increased glucuronidation of lorcaserin
CTD
PMID:22259019
NCBI chr 9:88,696,981...88,808,465
Ensembl chr 9:88,713,184...88,808,465
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Ugt2b1
UDP glucuronosyltransferase 2 family, polypeptide B1
multiple interactions
ISO
UGT2B17 protein results in increased carbamoylation of and results in increased glucuronidation of lorcaserin
CTD
PMID:22259019
NCBI chr14:21,024,035...21,035,784
Ensembl chr14:21,024,006...21,035,986
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Ugt2b7
UDP glucuronosyltransferase family 2 member B7
multiple interactions
ISO
UGT2B7 protein results in increased carbamoylation of and results in increased glucuronidation of lorcaserin
CTD
PMID:22259019
NCBI chr14:20,896,682...20,919,604
Ensembl chr14:20,896,682...20,919,604
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Clu
clusterin
affects expression
ISO
Megestrol affects the expression of CLU protein
CTD
PMID:12388792
NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315
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Gal
galanin and GMAP prepropeptide
affects expression
ISO
Megestrol affects the expression of GAL protein
CTD
PMID:12388792
NCBI chr 1:200,650,439...200,655,302
Ensembl chr 1:200,650,439...200,654,959
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Gap43
growth associated protein 43
affects expression
ISO
Megestrol affects the expression of GAP43 protein
CTD
PMID:12388792
NCBI chr11:58,376,371...58,470,047
Ensembl chr11:58,376,371...58,470,045
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Nr1i2
nuclear receptor subfamily 1, group I, member 2
increases activity
ISO
Megestrol results in increased activity of NR1I2 protein
CTD
PMID:21068194
NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
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Ret
ret proto-oncogene
affects expression
ISO
Megestrol affects the expression of RET protein
CTD
PMID:12388792
NCBI chr 4:151,325,969...151,368,176
Ensembl chr 4:151,326,431...151,368,176
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Timp1
TIMP metallopeptidase inhibitor 1
affects expression
ISO
Megestrol affects the expression of TIMP1 protein
CTD
PMID:12388792
NCBI chr X:1,212,969...1,217,714
Ensembl chr X:1,212,972...1,217,664
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Abcb11
ATP binding cassette subfamily B member 11
decreases activity
ISO
Megestrol Acetate results in decreased activity of ABCB11 protein
CTD
PMID:23956101
NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
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Ahsa1
activator of Hsp90 ATPase activity 1
increases expression
ISO
Megestrol Acetate results in increased expression of AHSA1 protein
CTD
PMID:16939895
NCBI chr 6:106,913,296...106,921,347
Ensembl chr 6:106,913,530...106,921,345
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Ar
androgen receptor
multiple interactions
ISO
Megestrol Acetate binds to and results in decreased activity of AR protein
CTD
PMID:25752796
NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925
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Bcl11b
BCL11 transcription factor B
multiple interactions
EXP
[Ethinyl Estradiol co-treated with Megestrol Acetate] results in decreased expression of BCL11B mRNA
CTD
PMID:22085904
NCBI chr 6:126,834,531...126,927,720
Ensembl chr 6:126,834,531...126,928,224
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Cct6a
chaperonin containing TCP1 subunit 6A
increases expression
ISO
Megestrol Acetate results in increased expression of CCT6A protein
CTD
PMID:16939895
NCBI chr12:26,872,736...26,883,125
Ensembl chr12:26,872,574...26,883,337
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Cldn1
claudin 1
multiple interactions decreases expression
ISO
Megestrol Acetate results in decreased expression of and affects the localization of CLDN1 protein Megestrol Acetate results in decreased expression of CLDN1 mRNA
CTD
PMID:22883527
NCBI chr11:74,421,569...74,436,728
Ensembl chr11:74,421,569...74,436,724
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Cldn4
claudin 4
multiple interactions decreases expression
ISO
Megestrol Acetate results in decreased expression of and results in increased localization of CLDN4 protein Megestrol Acetate results in decreased expression of CLDN4 mRNA
CTD
PMID:23095775
NCBI chr12:21,751,638...21,753,436
Ensembl chr12:21,751,331...21,753,436
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Comt
catechol-O-methyltransferase
increases expression
ISO
Megestrol Acetate results in increased expression of COMT protein
CTD
PMID:16939895
NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642
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Esr1
estrogen receptor 1
multiple interactions
ISO
ESR1 protein affects the reaction [Megestrol Acetate results in increased expression of GREB1 mRNA]
CTD
PMID:33405908
NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
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Greb1
growth regulating estrogen receptor binding 1
increases expression multiple interactions
ISO
Megestrol Acetate results in increased expression of GREB1 mRNA ESR1 protein affects the reaction [Megestrol Acetate results in increased expression of GREB1 mRNA]; Fulvestrant inhibits the reaction [Megestrol Acetate results in increased expression of GREB1 mRNA]
CTD
PMID:33405908
NCBI chr 6:39,440,522...39,562,364
Ensembl chr 6:39,440,504...39,581,633
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Krt8
keratin 8
increases expression
ISO
Megestrol Acetate results in increased expression of KRT8 protein
CTD
PMID:16939895
NCBI chr 7:133,124,203...133,131,656
Ensembl chr 7:133,124,203...133,131,728
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Mmp12
matrix metallopeptidase 12
multiple interactions
EXP
[Ethinyl Estradiol co-treated with Megestrol Acetate] results in increased expression of MMP12 protein
CTD
PMID:22085904
NCBI chr 8:4,581,785...4,591,687
Ensembl chr 8:4,581,785...4,599,611
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Mmp3
matrix metallopeptidase 3
multiple interactions
EXP
[Ethinyl Estradiol co-treated with Megestrol Acetate] results in increased expression of MMP3 protein
CTD
PMID:22085904
NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961
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Mmp8
matrix metallopeptidase 8
multiple interactions
EXP
[Ethinyl Estradiol co-treated with Megestrol Acetate] results in increased expression of MMP8 protein
CTD
PMID:22085904
NCBI chr 8:4,724,009...4,733,864
Ensembl chr 8:4,724,029...4,733,520
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Pgr
progesterone receptor
multiple interactions
ISO
Megestrol Acetate binds to and results in increased activity of PGR protein
CTD
PMID:25752796
NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344
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Ppia
peptidylprolyl isomerase A
decreases expression
ISO
Megestrol Acetate results in decreased expression of PPIA protein
CTD
PMID:16939895
NCBI chr14:81,279,292...81,282,960
Ensembl chr14:81,275,091...81,299,601
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Rab6a
RAB6A, member RAS oncogene family
increases expression
ISO
Megestrol Acetate results in increased expression of RAB6A protein
CTD
PMID:16939895
NCBI chr 1:154,957,870...155,008,922
Ensembl chr 1:154,958,189...154,996,715
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Sf3a3
splicing factor 3a, subunit 3
increases expression
ISO
Megestrol Acetate results in increased expression of SF3A3 protein
CTD
PMID:16939895
NCBI chr 5:136,967,713...136,987,345
Ensembl chr 5:136,967,691...136,987,361
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Sgk1
serum/glucocorticoid regulated kinase 1
increases expression multiple interactions
ISO
Megestrol Acetate results in increased expression of SGK1 mRNA Fulvestrant inhibits the reaction [Megestrol Acetate results in increased expression of SGK1 mRNA]
CTD
PMID:33405908
NCBI chr 1:22,980,257...23,098,122
Ensembl chr 1:22,980,261...23,098,283
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Slc22a2
solute carrier family 22 member 2
multiple interactions
ISO
Megestrol Acetate inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium]
CTD
PMID:21599003
NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268
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Tnc
tenascin C
multiple interactions
EXP
[Ethinyl Estradiol co-treated with Megestrol Acetate] results in decreased expression of TNC mRNA
CTD
PMID:22085904
NCBI chr 5:77,375,851...77,460,712
Ensembl chr 5:77,375,851...77,460,624
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Acaca
acetyl-CoA carboxylase alpha
affects expression
ISO
Rimonabant affects the expression of ACACA mRNA
CTD
PMID:20110567
NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457
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Acacb
acetyl-CoA carboxylase beta
increases expression
ISO
Rimonabant results in increased expression of ACACB mRNA
CTD
PMID:20110567
NCBI chr12:42,365,800...42,477,651
Ensembl chr12:42,366,548...42,457,655
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Acadm
acyl-CoA dehydrogenase medium chain
affects expression multiple interactions
ISO
Rimonabant affects the expression of ACADM mRNA Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ACADM mRNA]
CTD
PMID:19030233
NCBI chr 2:242,858,865...242,883,036
Ensembl chr 2:242,858,865...242,883,147
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Acbd5
acyl-CoA binding domain containing 5
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ACBD5 mRNA]
CTD
PMID:19030233
NCBI chr17:85,206,178...85,248,909
Ensembl chr17:85,206,303...85,248,215
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Acta2
actin alpha 2, smooth muscle
decreases expression
EXP
Rimonabant results in decreased expression of ACTA2 mRNA
CTD
PMID:21863215
NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
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Actr2
actin related protein 2
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ACTR2 mRNA]
CTD
PMID:19030233
NCBI chr14:94,296,443...94,333,735
Ensembl chr14:94,296,443...94,340,524
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Adamts1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ADAMTS1 mRNA]
CTD
PMID:19030233
NCBI chr11:24,932,227...24,941,068
Ensembl chr11:24,931,761...24,941,103
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Adgre1
adhesion G protein-coupled receptor E1
decreases expression
EXP
Rimonabant results in decreased expression of ADGRE1 mRNA
CTD
PMID:30365523
NCBI chr 9:2,242,476...2,398,000
Ensembl chr 9:2,242,474...2,398,000
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Adipoq
adiponectin, C1Q and collagen domain containing
increases expression
ISO
Rimonabant results in increased expression of ADIPOQ mRNA; Rimonabant results in increased expression of ADIPOQ protein
CTD
PMID:16282221 PMID:20110567
NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
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Agap2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
multiple interactions increases expression
ISO
Rimonabant inhibits the reaction [MIR762 mRNA results in decreased expression of AGAP2 mRNA]; Rimonabant promotes the reaction [Dietary Fats results in increased expression of AGAP2 mRNA] Rimonabant results in increased expression of AGAP2 mRNA
CTD
PMID:30910812
NCBI chr 7:62,897,282...62,914,295
Ensembl chr 7:62,897,282...62,914,295
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Akt1
AKT serine/threonine kinase 1
multiple interactions
EXP ISO
Rimonabant inhibits the reaction [Dronabinol results in decreased phosphorylation of AKT1 protein] Rimonabant inhibits the reaction [Dronabinol results in increased phosphorylation of AKT1 protein]; Rimonabant inhibits the reaction [methanandamide results in increased phosphorylation of AKT1 protein]
CTD
PMID:12834810 PMID:31917333
NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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Alkbh1
alkB homolog 1, histone H2A dioxygenase
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of ALKBH1 mRNA]
CTD
PMID:19030233
NCBI chr 6:107,068,301...107,088,784
Ensembl chr 6:107,068,475...107,088,759
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Anxa1
annexin A1
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ANXA1 mRNA]
CTD
PMID:19030233
NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343
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Anxa2
annexin A2
multiple interactions affects expression
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ANXA2 mRNA] Rimonabant affects the expression of ANXA2 mRNA
CTD
PMID:19030233
NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658
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Apob
apolipoprotein B
increases secretion
ISO
Rimonabant results in increased secretion of APOB protein
CTD
PMID:20110567
NCBI chr 6:30,844,386...30,883,983
Ensembl chr 6:30,844,368...30,892,497
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App
amyloid beta precursor protein
affects expression multiple interactions
ISO
Rimonabant affects the expression of APP mRNA Rimonabant inhibits the reaction [Dietary Fats results in increased expression of APP mRNA]
CTD
PMID:19030233
NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
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Arg1
arginase 1
multiple interactions
ISO
Rimonabant promotes the reaction [Dietary Fats results in increased expression of ARG1]
CTD
PMID:30910812
NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422
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Arhgef12
Rho guanine nucleotide exchange factor 12
affects expression multiple interactions
ISO
Rimonabant affects the expression of ARHGEF12 mRNA Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ARHGEF12 mRNA]
CTD
PMID:19030233
NCBI chr 8:43,350,070...43,475,404
Ensembl chr 8:43,353,799...43,476,366
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Arpp19
cAMP-regulated phosphoprotein 19
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ARPP19 mRNA]
CTD
PMID:19030233
NCBI chr 8:75,779,640...75,802,474
Ensembl chr 8:75,779,523...75,802,452 Ensembl chr 8:75,779,523...75,802,452
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Arrb2
arrestin, beta 2
multiple interactions
ISO
Rimonabant inhibits the reaction [1-pentyl-3-(1-naphthoyl)indole promotes the reaction [ARRB2 protein binds to CNR1 protein]]; Rimonabant inhibits the reaction [1-pentyl-3-(1-naphthoyl)indole promotes the reaction [ARRB2 protein binds to CNR2 protein]]
CTD
PMID:27779402
NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850
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Atf4
activating transcription factor 4
multiple interactions
ISO
[Rimonabant co-treated with SR 144528] inhibits the reaction [Dronabinol results in increased expression of ATF4 mRNA]
CTD
PMID:31054322
NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
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Atf6
activating transcription factor 6
multiple interactions
ISO
[Rimonabant co-treated with SR 144528] inhibits the reaction [Dronabinol results in increased expression of ATF6 mRNA]
CTD
PMID:31054322
NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177
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Atp5me
ATP synthase membrane subunit e
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of ATP5ME mRNA]
CTD
PMID:19030233
NCBI chr14:1,319,868...1,320,996
Ensembl chr14:1,319,868...1,321,013
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Atrnl1
attractin like 1
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ATRNL1 mRNA]
CTD
PMID:19030233
NCBI chr 1:256,670,976...257,219,291
Ensembl chr 1:256,670,627...257,213,197
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Aurkb
aurora kinase B
decreases expression
ISO
Rimonabant results in decreased expression of AURKB protein
CTD
PMID:19479993
NCBI chr10:53,744,290...53,750,831
Ensembl chr10:53,745,142...53,750,837
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Bax
BCL2 associated X, apoptosis regulator
multiple interactions
ISO
Rimonabant inhibits the reaction [forsythiaside inhibits the reaction [amyloid beta-protein (25-35) results in increased expression of BAX protein]] Rimonabant inhibits the reaction [Cannabidiol results in decreased expression of BAX protein]
CTD
PMID:27932991 PMID:30769029
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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Bcl2
BCL2, apoptosis regulator
multiple interactions
ISO
Rimonabant inhibits the reaction [forsythiaside inhibits the reaction [amyloid beta-protein (25-35) results in decreased expression of BCL2 protein]]; Rimonabant inhibits the reaction [LEP gene mutant form results in decreased expression of BCL2 protein]
CTD
PMID:26967640 PMID:30769029
NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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Bdnf
brain-derived neurotrophic factor
multiple interactions
ISO
Rimonabant inhibits the reaction [Dronabinol results in increased expression of BDNF mRNA]
CTD
PMID:20929960
NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
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Braf
B-Raf proto-oncogene, serine/threonine kinase
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of BRAF mRNA]
CTD
PMID:19030233
NCBI chr 4:68,375,484...68,510,652
Ensembl chr 4:68,384,649...68,510,463
G
Bzw1
basic leucine zipper and W2 domains 1
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of BZW1 mRNA]
CTD
PMID:19030233
NCBI chr 9:59,930,672...59,944,468
Ensembl chr 9:59,930,744...59,944,430
G
C1galt1
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of C1GALT1 mRNA]
CTD
PMID:19030233
NCBI chr 4:35,930,981...35,966,100
Ensembl chr 4:35,928,104...35,961,831
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Cab39l
calcium binding protein 39-like
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CAB39L mRNA]
CTD
PMID:19030233
NCBI chr15:33,606,588...33,710,518
Ensembl chr15:33,606,694...33,743,545
G
Calm1
calmodulin 1
multiple interactions affects expression
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CALM1 mRNA] Rimonabant affects the expression of CALM1 mRNA
CTD
PMID:19030233
NCBI chr 6:119,487,691...119,495,759
Ensembl chr 6:119,487,621...119,498,227
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Canx
calnexin
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CANX mRNA]
CTD
PMID:19030233
NCBI chr10:34,623,865...34,656,866
Ensembl chr10:34,625,191...34,656,821
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Capn7
calpain 7
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CAPN7 mRNA]
CTD
PMID:19030233
NCBI chr16:6,545,630...6,581,908
Ensembl chr16:6,545,731...6,581,905
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Cartpt
CART prepropeptide
multiple interactions increases response to substance affects expression
ISO
FAAH affects the reaction [Rimonabant affects the expression of CARTPT protein] CARTPT results in increased susceptibility to Rimonabant
CTD
PMID:16131814
NCBI chr 2:31,255,098...31,257,452
Ensembl chr 2:31,255,098...31,290,713
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Casp1
caspase 1
multiple interactions
ISO
Rimonabant inhibits the reaction [Cannabidiol results in decreased expression of CASP1 protein]
CTD
PMID:27932991
NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
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Casp12
caspase 12
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CASP12 mRNA]
CTD
PMID:19030233
NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037
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Casp3
caspase 3
multiple interactions
ISO
Rimonabant inhibits the reaction [XLR-11 results in increased activity of CASP3 protein] Rimonabant inhibits the reaction [forsythiaside inhibits the reaction [amyloid beta-protein (25-35) results in increased cleavage of CASP3 protein]]; Rimonabant inhibits the reaction [JZL 184 inhibits the reaction [Sulfur Dioxide results in increased cleavage of and results in increased activity of CASP3 protein]]
CTD
PMID:26209559 PMID:29410032 PMID:30769029
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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Cav1
caveolin 1
affects expression multiple interactions
ISO
Rimonabant affects the expression of CAV1 mRNA Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CAV1 mRNA]
CTD
PMID:19030233
NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
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Cav2
caveolin 2
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CAV2 mRNA]
CTD
PMID:19030233
NCBI chr 4:45,616,766...45,624,144
Ensembl chr 4:45,616,712...45,624,244
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Cavin1
caveolae associated protein 1
affects expression
ISO
Rimonabant affects the expression of CAVIN1 mRNA
CTD
PMID:19030233
NCBI chr10:85,884,100...85,896,136
Ensembl chr10:85,889,036...85,896,120
G
Ccar1
cell division cycle and apoptosis regulator 1
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CCAR1 mRNA]
CTD
PMID:19030233
NCBI chr20:30,685,916...30,728,531
Ensembl chr20:30,685,916...30,728,526
G
Ccl2
C-C motif chemokine ligand 2
multiple interactions decreases expression
ISO EXP
Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased expression of CCL2] Rimonabant results in decreased expression of CCL2 mRNA
CTD
PMID:30365523 PMID:32832534
NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
G
Ccl3
C-C motif chemokine ligand 3
multiple interactions
ISO
Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased expression of CCL3]
CTD
PMID:32832534
NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
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Ccnb1
cyclin B1
increases expression
ISO
Rimonabant results in increased expression of CCNB1 protein
CTD
PMID:19479993
NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
G
Ccnd1
cyclin D1
decreases expression
ISO
Rimonabant results in decreased expression of CCND1 protein
CTD
PMID:16822929
NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
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Ccnd2
cyclin D2
multiple interactions
ISO
Rimonabant inhibits the reaction [LEP gene mutant form results in decreased expression of CCND2 protein]
CTD
PMID:26967640
NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495
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Ccng1
cyclin G1
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CCNG1 mRNA]
CTD
PMID:19030233
NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641
G
Ccpg1
cell cycle progression 1
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CCPG1 mRNA]
CTD
PMID:19030233
NCBI chr 8:73,719,960...73,752,437
Ensembl chr 8:73,719,955...73,752,430
G
Ccr7
C-C motif chemokine receptor 7
multiple interactions
ISO
[Rimonabant co-treated with MIR762 mRNA] affects the expression of CCR7 mRNA
CTD
PMID:30910812
NCBI chr10:84,098,193...84,108,309
Ensembl chr10:84,097,381...84,108,309
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Cd36
CD36 molecule
affects expression multiple interactions
ISO
Rimonabant affects the expression of CD36 mRNA Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CD36 mRNA]
CTD
PMID:19030233
NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
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Cdc73
cell division cycle 73
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CDC73 mRNA]
CTD
PMID:19030233
NCBI chr13:55,357,226...55,449,690
Ensembl chr13:55,357,226...55,449,656
G
Cdk5
cyclin-dependent kinase 5
multiple interactions
ISO
Rimonabant inhibits the reaction [[Ethanol results in increased activity of CDK5 protein] which results in increased degradation of CDK5R1 protein]; Rimonabant inhibits the reaction [Ethanol results in increased activity of CDK5 protein]
CTD
PMID:30143782
NCBI chr 4:10,754,682...10,760,110
Ensembl chr 4:10,754,687...10,760,112
G
Cdk5r1
cyclin-dependent kinase 5 regulatory subunit 1
multiple interactions
ISO
Rimonabant inhibits the reaction [[Ethanol results in increased activity of CDK5 protein] which results in increased degradation of CDK5R1 protein]
CTD
PMID:30143782
NCBI chr10:65,484,266...65,485,467
Ensembl chr10:65,483,941...65,488,456
G
Cdkl2
cyclin dependent kinase like 2
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CDKL2 mRNA]
CTD
PMID:19030233
NCBI chr14:16,027,381...16,063,257
Ensembl chr14:16,028,363...16,063,252
G
Cdkn1b
cyclin-dependent kinase inhibitor 1B
increases expression
ISO
Rimonabant results in increased expression of CDKN1B protein
CTD
PMID:16822929
NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
G
Cebpa
CCAAT/enhancer binding protein alpha
multiple interactions
ISO
Rimonabant inhibits the reaction [butylparaben results in increased expression of CEBPA mRNA]
CTD
PMID:27659731
NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412
G
Cebpd
CCAAT/enhancer binding protein delta
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of CEBPD mRNA]
CTD
PMID:19030233
NCBI chr11:84,764,670...84,765,808
Ensembl chr11:84,764,565...84,765,829
G
Chd9
chromodomain helicase DNA binding protein 9
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CHD9 mRNA]
CTD
PMID:19030233
NCBI chr19:15,941,535...16,146,220
Ensembl chr19:15,942,687...16,164,556
G
Chek1
checkpoint kinase 1
decreases phosphorylation
ISO
Rimonabant results in decreased phosphorylation of CHEK1 protein
CTD
PMID:19479993
NCBI chr 8:36,420,565...36,443,477
Ensembl chr 8:36,420,569...36,441,009
G
Clic4
chloride intracellular channel 4
affects expression multiple interactions
ISO
Rimonabant affects the expression of CLIC4 mRNA Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CLIC4 mRNA]
CTD
PMID:19030233
NCBI chr 5:147,453,702...147,513,455
Ensembl chr 5:147,453,712...147,513,452
G
Cltc
clathrin heavy chain
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CLTC mRNA]
CTD
PMID:19030233
NCBI chr10:71,517,661...71,574,591
Ensembl chr10:71,517,663...71,573,737
G
Cnot1
CCR4-NOT transcription complex, subunit 1
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CNOT1 mRNA]
CTD
PMID:19030233
NCBI chr19:9,255,190...9,346,574
Ensembl chr19:9,255,194...9,346,574
G
Cnp
2',3'-cyclic nucleotide 3' phosphodiesterase
multiple interactions
ISO
Rimonabant inhibits the reaction [Dronabinol results in increased expression of CNP protein]
CTD
PMID:32956517
NCBI chr10:85,511,164...85,517,723
Ensembl chr10:85,511,160...85,517,720
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Cnr1
cannabinoid receptor 1
multiple interactions decreases activity affects localization affects binding decreases expression
ISO EXP
1-(4-chlorophenyl)-3-(3-(6-pyrrolidin-1-ylpyridin-2-yl)phenyl)urea analog inhibits the reaction [Rimonabant binds to CNR1 protein]; 1-(4-chlorophenyl)-3-(3-(6-pyrrolidin-1-ylpyridin-2-yl)phenyl)urea inhibits the reaction [Rimonabant binds to CNR1 protein]; 3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol inhibits the reaction [Rimonabant binds to CNR1 protein]; 5F-CUMYL-PICA inhibits the reaction [Rimonabant binds to CNR1 protein]; AM 6527 inhibits the reaction [Rimonabant binds to CNR1 protein]; arachidonyl dopamine inhibits the reaction [Rimonabant binds to CNR1 protein]; Dronabinol inhibits the reaction [Rimonabant binds to CNR1 protein]; methyl 2-(1-(4-fluorobenzyl)-1H-indazole-3-carboxamido)-3-methylbutanoate analog inhibits the reaction [Rimonabant binds to CNR1 protein]; methyl 2-(1-(4-fluorobenzyl)-1H-indazole-3-carboxamido)-3-methylbutanoate inhibits the reaction [Rimonabant binds to CNR1 protein]; N'-((3Z)-1-(1-hexyl)-2-oxo-1,2-dihydro-3H-indol-3-ylidene)benzohydrazide affects the reaction [Rimonabant binds to CNR1 protein]; N-1-naphthalenyl-1-pentyl-1H-indazole-3-carboxamide inhibits the reaction [Rimonabant binds to CNR1 protein]; Rimonabant binds to and results in decreased activity of CNR1 protein; Rimonabant inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased activity of CNR1]; Rimonabant inhibits the reaction [1-pentyl-3-(1-naphthoyl)indole promotes the reaction [ARRB2 protein binds to CNR1 protein]]; Rimonabant inhibits the reaction [1-pentyl-3-(1-naphthoyl)indole results in increased activity of CNR1 protein]; Rimonabant inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] which results in increased abundance of Cyclic AMP]; Rimonabant inhibits the reaction [anandamide results in increased activity of CNR1]; Rimonabant inhibits the reaction [Dronabinol results in increased expression of CNR1 mRNA]; Rimonabant inhibits the reaction [HU 211 results in increased activity of CNR1] Rimonabant results in decreased activity of CNR1 protein Rimonabant affects the localization of CNR1 protein Rimonabant results in decreased expression of CNR1 mRNA [Rimonabant binds to and results in decreased activity of CNR1 protein] which results in decreased susceptibility to (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone; [Rimonabant binds to and results in decreased activity of CNR1 protein] which results in decreased susceptibility to palmidrol analog; Cannabidiol inhibits the reaction [Poly I-C inhibits the reaction [Rimonabant binds to CNR1 protein]]; Poly I-C inhibits the reaction [Rimonabant binds to CNR1 protein]; Rimonabant binds to and results in decreased activity of CNR1 protein; Rimonabant inhibits the reaction [1-(5-fluoropentyl)-3-(1-naphthoyl)indole analog binds to CNR1 protein]; Rimonabant inhibits the reaction [1-(5-fluoropentyl)-3-(1-naphthoyl)indole binds to CNR1 protein]; Rimonabant inhibits the reaction [[(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone binds to and results in increased activity of CNR1 protein] inhibits the reaction [Potassium Chloride results in increased transport of Calcium]]; Rimonabant inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [IFNG protein affects the reaction [Lipopolysaccharides results in increased abundance of Nitric Oxide]]]; Rimonabant inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Potassium Chloride results in increased transport of Calcium]]; Rimonabant inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] which results in decreased abundance of Nitric Oxide]; Rimonabant inhibits the reaction [Dronabinol results in increased activity of CNR1 protein] 6-methyl-3-(2-nitro-1-(thiophen-2-yl)propyl)-2-phenyl-1H-indole inhibits the reaction [Rimonabant binds to CNR1 protein]; [Rimonabant binds to and results in decreased activity of CNR1 protein] which affects the expression of FOS protein; [Rimonabant binds to and results in decreased activity of CNR1 protein] which results in decreased susceptibility to Nicotine; Rimonabant binds to and results in decreased activity of CNR1 protein; Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein]; Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased expression of CNR1 mRNA]; Rimonabant inhibits the reaction [5F-ADB cannabinoid binds to and results in increased activity of CNR1 protein]; Rimonabant inhibits the reaction [5F-ADB cannabinoid metabolite binds to and results in increased activity of CNR1 protein]; Rimonabant inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Lipopolysaccharides results in increased transport of Nitric Oxide]]; Rimonabant inhibits the reaction [[anandamide binds to and results in increased activity of CNR1 protein] inhibits the reaction [Lipopolysaccharides results in increased transport of Nitric Oxide]]; Rimonabant inhibits the reaction [HU 211 binds to and results in increased activity of CNR1 protein]
CTD
PMID:10027878 PMID:10422789 PMID:10871313 PMID:11517236 PMID:11558437 PMID:11727767 PMID:11730719 PMID:11891798 PMID:12421626 PMID:12509806 PMID:12560108 PMID:15280883 PMID:16113085 PMID:16148442 PMID:16416159 PMID:16554168 PMID:16822929 PMID:17018694 PMID:17558434 PMID:17572696 PMID:18536748 PMID:20107430 PMID:20110567 PMID:20522703 PMID:21702498 PMID:26052038 PMID:26397760 PMID:26398720 PMID:26558620 PMID:27307500 PMID:27513693 PMID:27779402 PMID:29230395 PMID:29410032 PMID:29549157 PMID:30322873 PMID:31202911 PMID:32832534 PMID:35201352 More...
NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099
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Cnr2
cannabinoid receptor 2
multiple interactions
ISO
Rimonabant inhibits the reaction [1-pentyl-3-(1-naphthoyl)indole promotes the reaction [ARRB2 protein binds to CNR2 protein]]; Rimonabant inhibits the reaction [1-pentyl-3-(1-naphthoyl)indole results in increased activity of CNR2 protein]
CTD
PMID:27779402
NCBI chr 5:148,125,222...148,151,548
Ensembl chr 5:148,125,604...148,151,548
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Col1a1
collagen type I alpha 1 chain
decreases expression
EXP
Rimonabant results in decreased expression of COL1A1 mRNA
CTD
PMID:21863215 PMID:30365523
NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
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Copg2
COPI coat complex subunit gamma 2
affects expression multiple interactions
ISO
Rimonabant affects the expression of COPG2 mRNA Rimonabant inhibits the reaction [Dietary Fats results in increased expression of COPG2 mRNA]
CTD
PMID:19030233
NCBI chr 4:59,366,086...59,501,591
Ensembl chr 4:59,366,086...59,501,618
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Cpt1a
carnitine palmitoyltransferase 1A
increases expression
EXP
Rimonabant results in increased expression of CPT1A mRNA
CTD
PMID:30365523
NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
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Creb1
cAMP responsive element binding protein 1
multiple interactions
EXP ISO
Rimonabant inhibits the reaction [Dronabinol results in increased phosphorylation of CREB1 protein] Rimonabant inhibits the reaction [Dronabinol results in decreased expression of and results in decreased phosphorylation of CREB1 protein]
CTD
PMID:15913574 PMID:19912468
NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
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Creb3l2
cAMP responsive element binding protein 3-like 2
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CREB3L2 mRNA]
CTD
PMID:19030233
NCBI chr 4:65,907,570...66,112,078
Ensembl chr 4:65,907,655...66,023,763
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Crh
corticotropin releasing hormone
decreases expression multiple interactions
EXP
Rimonabant results in decreased expression of CRH mRNA Dronabinol affects the reaction [Rimonabant results in decreased expression of CRH mRNA]; Rimonabant inhibits the reaction [HU 211 results in decreased expression of CRH mRNA]
CTD
PMID:12968131 PMID:15099659
NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919
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Csde1
cold shock domain containing E1
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CSDE1 mRNA]
CTD
PMID:19030233
NCBI chr 2:190,546,015...190,582,787
Ensembl chr 2:190,554,980...190,582,784
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Cul1
cullin 1
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CUL1 mRNA]
CTD
PMID:19030233
NCBI chr 4:76,551,952...76,625,830
Ensembl chr 4:76,551,983...76,627,980
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Cul3
cullin 3
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CUL3 mRNA]
CTD
PMID:19030233
NCBI chr 9:81,592,641...81,670,428
Ensembl chr 9:81,592,641...81,670,462
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Cxadr
CXADR, Ig-like cell adhesion molecule
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CXADR mRNA]
CTD
PMID:19030233
NCBI chr11:16,982,864...17,030,078
Ensembl chr11:16,982,860...17,030,046
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Cxcl10
C-X-C motif chemokine ligand 10
multiple interactions
ISO
Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased expression of CXCL10]
CTD
PMID:32832534
NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
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Cxcl3
C-X-C motif chemokine ligand 3
multiple interactions
ISO
Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased expression of CXCL1]
CTD
PMID:32832534
NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511
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Cyp4v3
cytochrome P450, family 4, subfamily v, polypeptide 3
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CYP4V3 mRNA]
CTD
PMID:19030233
NCBI chr16:46,917,929...46,958,735
Ensembl chr16:46,918,401...46,943,395
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Ddit3
DNA-damage inducible transcript 3
multiple interactions
ISO
[Rimonabant co-treated with SR 144528] inhibits the reaction [Dronabinol results in increased expression of DDIT3 mRNA]
CTD
PMID:31054322
NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
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Ddx27
DEAD-box helicase 27
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of DDX27 mRNA]
CTD
PMID:19030233
NCBI chr 3:155,744,182...155,763,380
Ensembl chr 3:155,744,150...155,763,372
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Ddx3x
DEAD-box helicase 3, X-linked
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of DDX3X mRNA]
CTD
PMID:19030233
NCBI chr X:9,479,532...9,493,169
Ensembl chr X:9,479,532...9,493,168
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Dnajc10
DnaJ heat shock protein family (Hsp40) member C10
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of DNAJC10 mRNA]
CTD
PMID:19030233
NCBI chr 3:65,232,031...65,272,732
Ensembl chr 3:65,232,697...65,272,719
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Dpp4
dipeptidylpeptidase 4
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of DPP4 mRNA]
CTD
PMID:19030233
NCBI chr 3:46,962,233...47,043,870
Ensembl chr 3:46,962,243...47,043,901
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Dr1
down-regulator of transcription 1
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of DR1 mRNA]
CTD
PMID:19030233
NCBI chr14:1,458,223...1,469,578
Ensembl chr14:1,458,223...1,469,638
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Dync1i2
dynein cytoplasmic 1 intermediate chain 2
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of DYNC1I2 mRNA]
CTD
PMID:19030233
NCBI chr 3:56,033,882...56,085,080
Ensembl chr 3:56,033,917...56,085,080
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Edem1
ER degradation enhancing alpha-mannosidase like protein 1
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of EDEM1 mRNA]
CTD
PMID:19030233
NCBI chr 4:141,797,631...141,829,717
Ensembl chr 4:141,797,701...141,829,717
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Efna5
ephrin A5
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of EFNA5 mRNA]
CTD
PMID:19030233
NCBI chr 9:102,316,753...102,595,480
Ensembl chr 9:102,320,295...102,597,413
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Ehmt2
euchromatic histone lysine methyltransferase 2
multiple interactions
ISO
Rimonabant inhibits the reaction [Ethanol promotes the reaction [EHMT2 protein binds to RAC1 promoter]]
CTD
PMID:30143782
NCBI chr20:3,919,623...3,936,751
Ensembl chr20:3,919,624...3,941,547
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Eif4g2
eukaryotic translation initiation factor 4, gamma 2
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of EIF4G2 mRNA]
CTD
PMID:19030233
NCBI chr 1:165,181,433...165,193,583
Ensembl chr 1:165,181,434...165,193,588
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Eif5
eukaryotic translation initiation factor 5
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of EIF5 mRNA]
CTD
PMID:19030233
NCBI chr 6:130,589,162...130,597,656
Ensembl chr 6:130,589,143...130,597,656
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Ell2
elongation factor for RNA polymerase II 2
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ELL2 mRNA]
CTD
PMID:19030233
NCBI chr 2:5,189,375...5,258,781
Ensembl chr 2:5,189,971...5,258,781
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Eps15
epidermal growth factor receptor pathway substrate 15
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of EPS15 mRNA]
CTD
PMID:19030233
NCBI chr 5:124,045,865...124,146,221
Ensembl chr 5:124,045,926...124,146,221
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Ermp1
endoplasmic reticulum metallopeptidase 1
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ERMP1 mRNA]
CTD
PMID:19030233
NCBI chr 1:227,383,992...227,422,120
Ensembl chr 1:227,387,920...227,436,909
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Faah
fatty acid amide hydrolase
multiple interactions
EXP ISO
[(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone co-treated with Rimonabant] affects the expression of FAAH mRNA FAAH affects the reaction [Rimonabant affects the expression of CARTPT protein]; Rimonabant inhibits the reaction [FAAH gene mutant form results in increased susceptibility to anandamide]
CTD
PMID:16131814 PMID:27385208 PMID:32833042
NCBI chr 5:129,479,774...129,499,018
Ensembl chr 5:129,479,824...129,498,677
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Fam199x
family with sequence similarity 199, X-linked
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of FAM199X mRNA]
CTD
PMID:19030233
NCBI chr X:100,384,230...100,419,935
Ensembl chr X:100,384,225...100,414,938
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Far1
fatty acyl CoA reductase 1
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of FAR1 mRNA]
CTD
PMID:19030233
NCBI chr 1:167,644,622...167,705,868
Ensembl chr 1:167,644,677...167,705,730
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Fasn
fatty acid synthase
decreases expression multiple interactions
ISO
Rimonabant results in decreased expression of FASN mRNA Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of FASN mRNA]
CTD
PMID:19030233 PMID:20110567
NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
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Fbxl5
F-box and leucine-rich repeat protein 5
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of FBXL5 mRNA]
CTD
PMID:19030233
NCBI chr14:67,305,109...67,347,383
Ensembl chr14:67,267,801...67,347,383
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Fbxw7
F-box and WD repeat domain containing 7
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of FBXW7 mRNA]
CTD
PMID:19030233
NCBI chr 2:170,149,706...170,311,536
Ensembl chr 2:170,149,694...170,309,941
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Fem1a
fem-1 homolog A
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of FEM1A mRNA]
CTD
PMID:19030233
NCBI chr 9:1,091,695...1,093,901
Ensembl chr 9:1,090,527...1,100,628
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Fermt2
FERM domain containing kindlin 2
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of FERMT2 mRNA]
CTD
PMID:19030233
NCBI chr15:18,682,927...18,751,959
Ensembl chr15:18,682,927...18,751,811
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Fgf1
fibroblast growth factor 1
multiple interactions affects expression
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of FGF1 mRNA] Rimonabant affects the expression of FGF1 mRNA
CTD
PMID:19030233
NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,686,581...30,772,357
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Fmr1
fragile X messenger ribonucleoprotein 1
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of FMR1 mRNA]
CTD
PMID:19030233
NCBI chr X:147,240,239...147,278,057
Ensembl chr X:147,240,301...147,278,050
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Fndc3b
fibronectin type III domain containing 3B
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of FNDC3B mRNA]
CTD
PMID:19030233
NCBI chr 2:110,311,439...110,617,504
Ensembl chr 2:110,312,694...110,547,830
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Fos
Fos proto-oncogene, AP-1 transcription factor subunit
multiple interactions
EXP ISO
Rimonabant inhibits the reaction [Dronabinol results in increased expression of FOS protein] [Rimonabant binds to and results in decreased activity of CNR1 protein] which affects the expression of FOS protein; Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased expression of FOS protein]
CTD
PMID:9751146 PMID:12560108 PMID:15280883
NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
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Fosb
FosB proto-oncogene, AP-1 transcription factor subunit
multiple interactions
EXP
Rimonabant inhibits the reaction [Dronabinol results in increased expression of FOSB protein]
CTD
PMID:9751146
NCBI chr 1:78,954,312...78,961,492
Ensembl chr 1:78,954,115...78,961,465
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Fosl1
FOS like 1, AP-1 transcription factor subunit
multiple interactions
EXP
Rimonabant inhibits the reaction [Dronabinol results in increased expression of FOSL1 protein]
CTD
PMID:9751146
NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930
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Fosl2
FOS like 2, AP-1 transcription factor subunit
multiple interactions
EXP
Rimonabant inhibits the reaction [Dronabinol results in increased expression of FOSL2 protein]
CTD
PMID:9751146
NCBI chr 6:24,297,898...24,319,219
Ensembl chr 6:24,300,956...24,320,034
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Frmd4b
FERM domain containing 4B
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of FRMD4B mRNA]
CTD
PMID:19030233
NCBI chr 4:129,895,401...130,222,070
Ensembl chr 4:129,895,708...130,084,197
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G6pc3
glucose 6 phosphatase catalytic subunit 3
increases expression
ISO
Rimonabant results in increased expression of G6PC3 mRNA
CTD
PMID:20110567
NCBI chr10:87,146,987...87,151,223
Ensembl chr10:87,146,901...87,151,221
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Gapdh
glyceraldehyde-3-phosphate dehydrogenase
increases expression
ISO
Rimonabant results in increased expression of GAPDH mRNA
CTD
PMID:16282221
NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235
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Gfap
glial fibrillary acidic protein
decreases expression multiple interactions
ISO
Rimonabant results in decreased expression of GFAP protein Rimonabant inhibits the reaction [Dronabinol results in increased expression of GFAP mRNA]
CTD
PMID:21373835 PMID:36529297
NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589
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Ggps1
geranylgeranyl diphosphate synthase 1
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of GGPS1 mRNA]
CTD
PMID:19030233
NCBI chr17:51,263,262...51,282,471
Ensembl chr17:51,263,263...51,276,220
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Gls
glutaminase
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of GLS mRNA]
CTD
PMID:19030233
NCBI chr 9:49,344,616...49,416,900
Ensembl chr 9:49,344,781...49,416,900
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Gmfb
glia maturation factor, beta
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of GMFB mRNA]
CTD
PMID:19030233
NCBI chr15:20,069,923...20,081,005
Ensembl chr15:20,067,263...20,080,331
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Gpld1
glycosylphosphatidylinositol specific phospholipase D1
decreases expression
ISO
Rimonabant results in decreased expression of GPLD1 mRNA
CTD
PMID:20110567
NCBI chr17:40,084,427...40,132,035
Ensembl chr17:40,084,617...40,126,939
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Gpr55
G protein-coupled receptor 55
multiple interactions
ISO
Rimonabant binds to and results in increased activity of GPR55 protein
CTD
PMID:17876302
NCBI chr 9:86,584,906...86,640,601
Ensembl chr 9:86,590,885...86,640,613
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Gpt
glutamic--pyruvic transaminase
decreases expression
EXP ISO
Rimonabant results in decreased expression of GPT protein
CTD
PMID:28705172 PMID:30365523
NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
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Grb14
growth factor receptor bound protein 14
affects expression multiple interactions
ISO
Rimonabant affects the expression of GRB14 mRNA Rimonabant inhibits the reaction [Dietary Fats results in increased expression of GRB14 mRNA]
CTD
PMID:19030233
NCBI chr 3:49,568,210...49,683,805
Ensembl chr 3:49,568,210...49,683,889
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Gria1
glutamate ionotropic receptor AMPA type subunit 1
multiple interactions
ISO
Rimonabant inhibits the reaction [Dronabinol results in decreased expression of GRIA1] Rimonabant inhibits the reaction [Dronabinol results in decreased expression of GRIA1 mRNA]
CTD
PMID:19912468 PMID:29230395
NCBI chr10:41,210,713...41,527,283
Ensembl chr10:41,210,713...41,527,283
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Grin2a
glutamate ionotropic receptor NMDA type subunit 2A
multiple interactions
ISO
Rimonabant inhibits the reaction [Dronabinol results in decreased expression of GRIN2A]
CTD
PMID:19912468
NCBI chr10:5,629,683...6,053,262
Ensembl chr10:5,631,369...6,044,637
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Grin2b
glutamate ionotropic receptor NMDA type subunit 2B
multiple interactions
ISO
Rimonabant inhibits the reaction [Dronabinol results in decreased expression of GRIN2B]
CTD
PMID:19912468
NCBI chr 4:168,580,824...169,044,110
Ensembl chr 4:168,599,546...169,042,279
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Gsta1
glutathione S-transferase alpha 1
increases expression
EXP
Rimonabant results in increased expression of GSTA1 mRNA
CTD
PMID:30365523
NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121
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Hdhd2
haloacid dehalogenase-like hydrolase domain containing 2
affects expression
ISO
Rimonabant affects the expression of HDHD2 mRNA
CTD
PMID:19030233
NCBI chr18:70,488,315...70,526,471
Ensembl chr18:70,474,926...70,526,470
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Hif1a
hypoxia inducible factor 1 subunit alpha
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of HIF1A mRNA]
CTD
PMID:19030233
NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
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Hipk3
homeodomain interacting protein kinase 3
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of HIPK3 mRNA]
CTD
PMID:19030233
NCBI chr 3:90,796,980...90,866,701
Ensembl chr 3:90,800,296...90,867,759
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Hmox1
heme oxygenase 1
increases expression
EXP
Rimonabant results in increased expression of HMOX1 mRNA; Rimonabant results in increased expression of HMOX1 protein
CTD
PMID:30365523
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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Hnf4a
hepatocyte nuclear factor 4, alpha
decreases activity
ISO
Rimonabant results in decreased activity of HNF4A protein
CTD
PMID:31981244
NCBI chr 3:152,186,787...152,248,320
Ensembl chr 3:152,186,787...152,248,320
G
Hsp90aa1
heat shock protein 90 alpha family class A member 1
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of HSP90AA1 mRNA]
CTD
PMID:19030233
NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268
G
Hspa5
heat shock protein family A (Hsp70) member 5
multiple interactions
ISO
[Rimonabant co-treated with SR 144528] inhibits the reaction [Dronabinol results in increased expression of HSPA5 mRNA]
CTD
PMID:31054322
NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
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Hycc2
hyccin PI4KA lipid kinase complex subunit 2
affects expression
ISO
Rimonabant affects the expression of HYCC2 mRNA
CTD
PMID:19030233
NCBI chr 9:60,056,883...60,129,176
Ensembl chr 9:60,056,890...60,093,007
G
Icam1
intercellular adhesion molecule 1
decreases expression multiple interactions
ISO
Rimonabant results in decreased expression of ICAM1 protein Rimonabant inhibits the reaction [Glucose results in increased expression of ICAM1 protein]
CTD
PMID:21373835
NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
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Ifng
interferon gamma
multiple interactions
EXP
Rimonabant inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased abundance of Nitric Oxide]]; Rimonabant inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [IFNG protein affects the reaction [Lipopolysaccharides results in increased abundance of Nitric Oxide]]]; Rimonabant inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein co-treated with (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone] results in decreased expression of NOS2 mRNA]; Rimonabant inhibits the reaction [Cannabinol inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased abundance of Nitric Oxide]]
CTD
PMID:11520904 PMID:11727767
NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
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Igf1
insulin-like growth factor 1
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of IGF1 mRNA]
CTD
PMID:19030233
NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
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Igfbp5
insulin-like growth factor binding protein 5
affects expression multiple interactions
ISO
Rimonabant affects the expression of IGFBP5 mRNA Rimonabant inhibits the reaction [Dietary Fats results in increased expression of IGFBP5 mRNA]
CTD
PMID:19030233
NCBI chr 9:74,452,371...74,464,953
Ensembl chr 9:74,448,382...74,465,156
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Il10
interleukin 10
multiple interactions
ISO
Rimonabant inhibits the reaction [Dronabinol promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL10 protein]]
CTD
PMID:32385136
NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
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Il12rb2
interleukin 12 receptor subunit beta 2
multiple interactions
ISO
Rimonabant inhibits the reaction [Dronabinol results in decreased expression of IL12RB2 mRNA]
CTD
PMID:14741435 PMID:18792785
NCBI chr 4:96,426,396...96,515,251
Ensembl chr 4:96,426,842...96,515,289
G
Il18
interleukin 18
multiple interactions
ISO
Rimonabant inhibits the reaction [Cannabidiol results in decreased expression of IL18 protein]
CTD
PMID:27932991
NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
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Il1b
interleukin 1 beta
multiple interactions
ISO
[Rimonabant co-treated with SR 144528] inhibits the reaction [OMDM-1 cpd inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]]; Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased expression of IL1B]; Rimonabant inhibits the reaction [OMDM-1 cpd inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]]; Rimonabant promotes the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]
CTD
PMID:15748152 PMID:32832534
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
G
Il6
interleukin 6
multiple interactions
ISO
Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased expression of IL6]
CTD
PMID:32832534
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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Ins1
insulin 1
multiple interactions decreases expression
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of INS1 protein]; Rimonabant inhibits the reaction [Dietary Fats results in increased secretion of INS1 protein]; Rimonabant inhibits the reaction [LEP gene mutant form results in decreased expression of INS1 protein] Rimonabant results in decreased expression of INS1 protein
CTD
PMID:19030233 PMID:26563389 PMID:26967640 PMID:30910812
NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536
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Ins2
insulin 2
decreases expression
ISO
Rimonabant results in decreased expression of INS protein
CTD
PMID:20110567
NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
G
Iqgap1
IQ motif containing GTPase activating protein 1
multiple interactions affects expression
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of IQGAP1 mRNA] Rimonabant affects the expression of IQGAP1 mRNA
CTD
PMID:19030233
NCBI chr 1:134,679,581...134,769,776
Ensembl chr 1:134,679,586...134,769,755
G
Irf5
interferon regulatory factor 5
multiple interactions
ISO
Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased expression of IRF5]
CTD
PMID:32832534
NCBI chr 4:58,127,577...58,140,665
Ensembl chr 4:58,127,640...58,139,267
G
Itgam
integrin subunit alpha M
decreases expression
EXP
Rimonabant results in decreased expression of ITGAM mRNA
CTD
PMID:30365523
NCBI chr 1:182,659,047...182,709,501
Ensembl chr 1:182,659,000...182,709,503
G
Itgav
integrin subunit alpha V
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ITGAV mRNA]
CTD
PMID:19030233
NCBI chr 3:68,838,514...68,926,653
Ensembl chr 3:68,838,189...68,926,639
G
Itgb1
integrin subunit beta 1
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ITGB1 mRNA]
CTD
PMID:19030233
NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195
G
Itpr2
inositol 1,4,5-trisphosphate receptor, type 2
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ITPR2 mRNA]
CTD
PMID:19030233
NCBI chr 4:179,028,594...179,434,657
Ensembl chr 4:179,027,281...179,404,164
G
Ivns1abp
influenza virus NS1A binding protein
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of IVNS1ABP mRNA]
CTD
PMID:19030233
NCBI chr13:63,427,040...63,446,701
Ensembl chr13:63,427,041...63,446,701
G
Kif5b
kinesin family member 5B
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of KIF5B mRNA]
CTD
PMID:19030233
NCBI chr17:51,489,904...51,527,508
Ensembl chr17:51,489,944...51,527,508
G
Klf4
KLF transcription factor 4
increases expression multiple interactions
ISO
Rimonabant results in increased expression of KLF4 mRNA MIR466J mRNA affects the reaction [Rimonabant results in increased expression of KLF4 mRNA]; Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of KLF4 mRNA]
CTD
PMID:30910812
NCBI chr 5:70,278,843...70,283,751
Ensembl chr 5:70,278,972...70,283,602
G
Klf6
KLF transcription factor 6
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of KLF6 mRNA]
CTD
PMID:19030233
NCBI chr17:64,539,456...64,548,451
Ensembl chr17:64,531,463...64,588,570
G
Klhl9
kelch-like family member 9
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of KLHL9 mRNA]
CTD
PMID:19030233
NCBI chr 5:103,333,747...103,337,931
G
Kpna3
karyopherin subunit alpha 3
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of KPNA3 mRNA]
CTD
PMID:19030233
NCBI chr15:35,536,310...35,610,066
Ensembl chr15:35,536,316...35,610,419
G
Kpnb1
karyopherin subunit beta 1
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of KPNB1 mRNA]
CTD
PMID:19030233
NCBI chr10:82,145,662...82,174,437
Ensembl chr10:82,145,420...82,174,605
G
Lamp2
lysosomal-associated membrane protein 2
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of LAMP2 mRNA]
CTD
PMID:19030233
NCBI chr X:117,173,097...117,222,090
Ensembl chr X:117,057,606...117,260,522
G
Large1
LARGE xylosyl- and glucuronyltransferase 1
multiple interactions affects expression
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of LARGE1 mRNA] Rimonabant affects the expression of LARGE1 mRNA
CTD
PMID:19030233
NCBI chr19:11,603,129...12,048,930
Ensembl chr19:11,603,129...12,048,930
G
Lep
leptin
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased secretion of LEP protein]; Rimonabant inhibits the reaction [LEP gene mutant form results in decreased expression of BCL2 protein]; Rimonabant inhibits the reaction [LEP gene mutant form results in decreased expression of CCND2 protein]; Rimonabant inhibits the reaction [LEP gene mutant form results in decreased expression of INS1 protein]
CTD
PMID:19030233 PMID:26967640
NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
G
Lhb
luteinizing hormone subunit beta
multiple interactions
EXP
Rimonabant inhibits the reaction [Dronabinol results in decreased expression of LHB protein]
CTD
PMID:9825732
NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972 Ensembl chr 1:95,900,984...95,901,972
G
Lipc
lipase C, hepatic type
increases expression
ISO
Rimonabant results in increased expression of LIPC mRNA
CTD
PMID:20110567
NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464
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Lipe
lipase E, hormone sensitive type
affects expression
ISO
Rimonabant affects the expression of LIPE mRNA
CTD
PMID:20110567
NCBI chr 1:80,965,612...80,984,313
Ensembl chr 1:80,965,627...80,984,310
G
Lmo1
LIM domain only 1
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of LMO1 mRNA]
CTD
PMID:19030233
NCBI chr 1:163,132,338...163,168,521
Ensembl chr 1:163,132,339...163,168,522
G
Lpgat1
lysophosphatidylglycerol acyltransferase 1
affects expression
ISO
Rimonabant affects the expression of LPGAT1 mRNA
CTD
PMID:19030233
NCBI chr13:103,294,622...103,365,372
Ensembl chr13:103,294,528...103,362,333
G
Lrrfip1
LRR binding FLII interacting protein 1
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of LRRFIP1 mRNA]
CTD
PMID:19030233
NCBI chr 9:91,592,032...91,720,250
Ensembl chr 9:91,643,197...91,720,250
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Mag
myelin-associated glycoprotein
multiple interactions
ISO
Rimonabant inhibits the reaction [Dronabinol results in increased expression of MAG protein]
CTD
PMID:32956517
NCBI chr 1:86,148,227...86,163,726
Ensembl chr 1:86,148,228...86,163,656
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Map1lc3b
microtubule-associated protein 1 light chain 3 beta
multiple interactions
ISO
Rimonabant results in increased expression of and results in increased lipidation of MAP1LC3B protein
CTD
PMID:31570772
NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
G
Mapk1
mitogen activated protein kinase 1
multiple interactions affects localization decreases activity
ISO EXP
Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased activity of MAPK1 protein]; Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased phosphorylation of MAPK1 protein]; Rimonabant inhibits the reaction [delta(9)-tetrahydrocannabinolic acid results in increased phosphorylation of MAPK1 protein]; Rimonabant inhibits the reaction [Dronabinol results in increased phosphorylation of MAPK1 protein]; Rimonabant inhibits the reaction [methanandamide results in increased phosphorylation of MAPK1 protein] Rimonabant inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Rimonabant inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Rimonabant inhibits the reaction [Dronabinol results in decreased phosphorylation of MAPK1 protein]; Rimonabant inhibits the reaction [Dronabinol results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Rimonabant inhibits the reaction [glyceryl 2-arachidonate results in decreased phosphorylation of MAPK1 protein]; Rimonabant inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK1 protein] Rimonabant affects the localization of MAPK1 protein Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased phosphorylation of MAPK1 protein]; Rimonabant inhibits the reaction [Dronabinol results in increased activity of MAPK1 protein]; Rimonabant inhibits the reaction [Dronabinol results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Rimonabant inhibits the reaction [HU 211 results in increased phosphorylation of MAPK1 protein] Rimonabant results in decreased activity of MAPK1 protein
CTD
PMID:8526880 PMID:11553284 PMID:12657697 PMID:12834810 PMID:16282221 PMID:16822929 PMID:18950629 PMID:31917333 PMID:32510591 More...
NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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Mapk3
mitogen activated protein kinase 3
multiple interactions decreases activity affects localization
ISO EXP
Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased phosphorylation of MAPK3 protein]; Rimonabant inhibits the reaction [Dronabinol results in increased activity of MAPK3 protein]; Rimonabant inhibits the reaction [Dronabinol results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Rimonabant inhibits the reaction [HU 211 results in increased phosphorylation of MAPK3 protein] Rimonabant inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Rimonabant inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Rimonabant inhibits the reaction [Dronabinol results in decreased phosphorylation of MAPK3 protein]; Rimonabant inhibits the reaction [Dronabinol results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Rimonabant inhibits the reaction [glyceryl 2-arachidonate results in decreased phosphorylation of MAPK3 protein]; Rimonabant inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK3 protein] Rimonabant results in decreased activity of MAPK3 protein Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased activity of MAPK3 protein]; Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased phosphorylation of MAPK3 protein]; Rimonabant inhibits the reaction [delta(9)-tetrahydrocannabinolic acid results in increased phosphorylation of MAPK3 protein]; Rimonabant inhibits the reaction [Dronabinol results in increased phosphorylation of MAPK3 protein]; Rimonabant inhibits the reaction [methanandamide results in increased phosphorylation of MAPK3 protein] Rimonabant affects the localization of MAPK3 protein
CTD
PMID:8526880 PMID:11553284 PMID:12657697 PMID:12834810 PMID:16282221 PMID:16822929 PMID:18950629 PMID:31917333 PMID:32510591 More...
NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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Mapk8
mitogen-activated protein kinase 8
multiple interactions
ISO
Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased phosphorylation of MAPK8 protein]; Rimonabant inhibits the reaction [HU 211 results in increased phosphorylation of MAPK8 protein]
CTD
PMID:18950629
NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
G
Marchf6
membrane associated ring-CH-type finger 6
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of MARCHF6 mRNA]
CTD
PMID:19030233
NCBI chr 2:82,455,686...82,532,917
Ensembl chr 2:82,455,689...82,532,910
G
Mbnl1
muscleblind-like splicing regulator 1
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of MBNL1 mRNA]
CTD
PMID:19030233
NCBI chr 2:144,639,819...144,814,395
Ensembl chr 2:144,670,285...144,814,368
G
Mbnl2
muscleblind-like splicing regulator 2
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of MBNL2 mRNA]
CTD
PMID:19030233
NCBI chr15:97,385,278...97,542,924
Ensembl chr15:97,385,244...97,542,937
G
Mef2c
myocyte enhancer factor 2C
multiple interactions
ISO
Rimonabant inhibits the reaction [Dronabinol results in increased expression of MEF2C mRNA]
CTD
PMID:36529297
NCBI chr 2:13,973,299...14,136,065
Ensembl chr 2:13,993,438...14,132,880
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Mest
mesoderm specific transcript
affects expression multiple interactions
ISO
Rimonabant affects the expression of MEST mRNA Rimonabant inhibits the reaction [Dietary Fats results in increased expression of MEST mRNA]
CTD
PMID:19030233
NCBI chr 4:59,354,445...59,364,919
Ensembl chr 4:59,354,447...59,366,145
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Mgll
monoglyceride lipase
affects response to substance
ISO
MGLL protein affects the susceptibility to Rimonabant
CTD
PMID:21911610
NCBI chr 4:121,192,186...121,294,187
Ensembl chr 4:121,192,195...121,294,179
G
Mir16
microRNA 16
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of MIR16 mRNA]
CTD
PMID:19030233
NCBI chr 2:153,245,349...153,245,443
Ensembl chr 2:153,245,349...153,245,443
G
Mlkl
mixed lineage kinase domain like pseudokinase
multiple interactions
ISO
Rimonabant inhibits the reaction [Quetiapine Fumarate affects the localization of MLKL protein]; Rimonabant inhibits the reaction [Quetiapine Fumarate results in increased expression of and results in increased phosphorylation of MLKL protein]
CTD
PMID:31220554
NCBI chr19:39,277,526...39,304,555
Ensembl chr19:39,276,785...39,304,502
G
Mmp13
matrix metallopeptidase 13
decreases expression
EXP
Rimonabant results in decreased expression of MMP13 mRNA
CTD
PMID:21863215
NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239
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Mog
myelin oligodendrocyte glycoprotein
multiple interactions
ISO
Rimonabant inhibits the reaction [Dronabinol results in increased expression of MOG protein]
CTD
PMID:32956517
NCBI chr20:1,513,137...1,523,473
Ensembl chr20:1,513,239...1,523,474
G
Mospd1
motile sperm domain containing 1
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of MOSPD1 mRNA]
CTD
PMID:19030233
NCBI chr X:133,100,200...133,127,960
Ensembl chr X:133,100,422...133,127,908 Ensembl chr 1:133,100,422...133,127,908
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Mycbp2
MYC binding protein 2
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of MYCBP2 mRNA]
CTD
PMID:19030233
NCBI chr15:79,937,354...80,175,432
Ensembl chr15:79,937,354...80,175,498
G
Nap1l1
nucleosome assembly protein 1-like 1
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of NAP1L1 mRNA]
CTD
PMID:19030233
NCBI chr 7:46,933,278...46,957,853
Ensembl chr 7:46,933,356...46,956,593
G
Napepld
N-acyl phosphatidylethanolamine phospholipase D
multiple interactions
EXP
[(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone co-treated with Rimonabant] affects the expression of NAPEPLD mRNA
CTD
PMID:32833042
NCBI chr 4:13,360,532...13,398,815
Ensembl chr 4:13,361,006...13,398,748
G
Ncl
nucleolin
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of NCL mRNA]
CTD
PMID:19030233
NCBI chr 9:86,999,588...87,008,112
Ensembl chr 9:86,998,019...87,008,136
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Ndc1
NDC1 transmembrane nucleoporin
affects expression
ISO
Rimonabant affects the expression of NDC1 mRNA
CTD
PMID:19030233
NCBI chr 5:122,155,992...122,202,295
Ensembl chr 5:122,155,967...122,202,291
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Ndufb11
NADH:ubiquinone oxidoreductase subunit B11
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of NDUFB11 mRNA]
CTD
PMID:19030233
NCBI chr X:1,572,805...1,575,063
Ensembl chr X:1,572,785...1,575,062
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Ndufb9
NADH:ubiquinone oxidoreductase subunit B9
multiple interactions affects expression
ISO
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of NDUFB9 mRNA] Rimonabant affects the expression of NDUFB9 mRNA
CTD
PMID:19030233
NCBI chr 7:90,480,948...90,487,367
Ensembl chr 7:90,436,621...90,488,009
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Ndufs8
NADH:ubiquinone oxidoreductase core subunit S8
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of NDUFS8 mRNA]
CTD
PMID:19030233
NCBI chr 1:201,140,585...201,144,573
Ensembl chr 1:201,140,585...201,144,511
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Nedd4
NEDD4 E3 ubiquitin protein ligase
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of NEDD4 mRNA]
CTD
PMID:19030233
NCBI chr 8:73,384,095...73,468,951
Ensembl chr 8:73,383,695...73,468,951
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Nek7
NIMA-related kinase 7
multiple interactions affects expression
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of NEK7 mRNA] Rimonabant affects the expression of NEK7 mRNA
CTD
PMID:19030233
NCBI chr13:50,022,212...50,149,374
Ensembl chr13:50,022,218...50,149,296
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Nes
nestin
multiple interactions
ISO
[Rimonabant co-treated with Dronabinol] results in increased expression of NES mRNA
CTD
PMID:36529297
NCBI chr 2:173,437,867...173,447,777
Ensembl chr 2:173,438,734...173,447,777
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Nfatc3
nuclear factor of activated T-cells 3
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of NFATC3 mRNA]
CTD
PMID:19030233
NCBI chr19:33,960,643...34,035,150
Ensembl chr19:33,960,852...34,035,150
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Nfe2l2
NFE2 like bZIP transcription factor 2
increases expression
EXP
Rimonabant results in increased expression of NFE2L2 mRNA
CTD
PMID:30365523
NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
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Nid1
nidogen 1
multiple interactions affects expression
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of NID1 mRNA] Rimonabant affects the expression of NID1 mRNA
CTD
PMID:19030233
NCBI chr17:86,085,133...86,158,272
Ensembl chr17:86,085,077...86,158,267
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Nlrp3
NLR family, pyrin domain containing 3
multiple interactions
ISO
Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased expression of NLRP3] Rimonabant inhibits the reaction [Cannabidiol results in decreased expression of NLRP3 protein]
CTD
PMID:27932991 PMID:32832534
NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811
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Nos2
nitric oxide synthase 2
multiple interactions
ISO EXP
[Rimonabant co-treated with SR 144528] inhibits the reaction [OMDM-1 cpd inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]]; Rimonabant inhibits the reaction [Dietary Fats results in increased expression of NOS2]; Rimonabant promotes the reaction [PF 3845 inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]] Rimonabant inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein co-treated with (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone] results in decreased expression of NOS2 mRNA]
CTD
PMID:11520904 PMID:15748152 PMID:30910812 PMID:31121907
NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
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Npr3
natriuretic peptide receptor 3
multiple interactions affects expression
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of NPR3 mRNA] Rimonabant affects the expression of NPR3 mRNA
CTD
PMID:19030233
NCBI chr 2:60,865,483...60,933,432
Ensembl chr 2:60,870,594...60,932,955
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Nqo1
NAD(P)H quinone dehydrogenase 1
increases expression
EXP
Rimonabant results in increased expression of NQO1 mRNA; Rimonabant results in increased expression of NQO1 protein
CTD
PMID:30365523
NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
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Nr3c1
nuclear receptor subfamily 3, group C, member 1
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of NR3C1 mRNA]
CTD
PMID:19030233
NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
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Ntn1
netrin 1
multiple interactions decreases expression
ISO
Rimonabant affects the reaction [Dietary Fats affects the expression of NTN1 protein]; Rimonabant inhibits the reaction [Dietary Fats results in increased expression of NTN1 mRNA]; Rimonabant inhibits the reaction [MIR762 mRNA results in increased expression of NTN1 mRNA] Rimonabant results in decreased expression of NTN1 mRNA
CTD
PMID:30910812
NCBI chr10:52,899,933...53,098,591
Ensembl chr10:52,899,934...53,085,326
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Opa1
OPA1, mitochondrial dynamin like GTPase
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of OPA1 mRNA]
CTD
PMID:19030233
NCBI chr11:71,108,100...71,185,170
Ensembl chr11:71,109,873...71,185,109
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Osbpl8
oxysterol binding protein-like 8
affects expression multiple interactions
ISO
Rimonabant affects the expression of OSBPL8 mRNA Rimonabant inhibits the reaction [Dietary Fats results in increased expression of OSBPL8 mRNA]
CTD
PMID:19030233
NCBI chr 7:46,596,944...46,749,888
Ensembl chr 7:46,596,983...46,749,888
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Pakap
paralemmin A kinase anchor protein
multiple interactions affects expression
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of PAKAP mRNA] Rimonabant affects the expression of PAKAP mRNA
CTD
PMID:19030233
NCBI chr 5:72,536,986...72,648,524 NCBI chr 5:72,313,646...72,450,645
Ensembl chr 5:72,181,718...72,648,524
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Parp1
poly (ADP-ribose) polymerase 1
decreases expression
ISO
Rimonabant results in decreased expression of PARP1 protein
CTD
PMID:19479993
NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
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Pc
pyruvate carboxylase
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of PCX mRNA]
CTD
PMID:19030233
NCBI chr 1:201,799,374...201,898,412
Ensembl chr 1:201,804,267...201,898,380
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Pck1
phosphoenolpyruvate carboxykinase 1
increases expression
ISO
Rimonabant results in increased expression of PCK1 mRNA
CTD
PMID:20110567
NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191
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Pcyox1
prenylcysteine oxidase 1
multiple interactions affects expression
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of PCYOX1 mRNA] Rimonabant affects the expression of PCYOX1 mRNA
CTD
PMID:19030233
NCBI chr 4:118,832,114...118,842,951
Ensembl chr 4:118,830,638...118,842,951
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Phip
pleckstrin homology domain interacting protein
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of PHIP mRNA]
CTD
PMID:19030233
NCBI chr 8:83,776,802...83,891,192
Ensembl chr 8:83,781,465...83,894,283
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Pik3ca
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
affects expression multiple interactions
ISO
Rimonabant affects the expression of PIK3CA mRNA Rimonabant inhibits the reaction [Dietary Fats results in increased expression of PIK3CA mRNA]
CTD
PMID:19030233
NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032
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Plac8
placenta associated 8
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of PLAC8 mRNA]
CTD
PMID:19030233
NCBI chr14:9,052,601...9,074,264
Ensembl chr14:9,063,048...9,074,264
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Plekha1
pleckstrin homology domain containing A1
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of PLEKHA1 mRNA]
CTD
PMID:19030233
NCBI chr 1:185,427,982...185,479,157
Ensembl chr 1:185,428,048...185,479,156
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Plin2
perilipin 2
decreases expression multiple interactions
ISO
Rimonabant results in decreased expression of PLIN2 protein Rimonabant inhibits the reaction [Oleic Acid results in increased expression of PLIN2 protein]
CTD
PMID:31570772
NCBI chr 5:101,156,648...101,211,738
Ensembl chr 5:101,154,411...101,242,319
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Pmm1
phosphomannomutase 1
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of PMM1 mRNA]
CTD
PMID:19030233
NCBI chr 7:113,466,632...113,477,004
Ensembl chr 7:113,466,632...113,477,022
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Pold2
DNA polymerase delta 2, accessory subunit
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of POLD2 mRNA]
CTD
PMID:19030233
NCBI chr14:80,748,971...80,755,188
Ensembl chr14:80,748,974...80,755,160
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Polr2j
RNA polymerase II subunit J
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of POLR2J mRNA]
CTD
PMID:19030233
NCBI chr12:20,543,038...20,548,590
Ensembl chr12:20,543,038...20,548,594
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Ppara
peroxisome proliferator activated receptor alpha
increases expression
EXP
Rimonabant results in increased expression of PPARA mRNA
CTD
PMID:30365523
NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
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Pparg
peroxisome proliferator-activated receptor gamma
affects expression
ISO
Rimonabant affects the expression of PPARG mRNA
CTD
PMID:20110567
NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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Ppfibp1
PPFIA binding protein 1
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of PPFIBP1 mRNA]
CTD
PMID:19030233
NCBI chr 4:179,807,579...179,951,428
Ensembl chr 4:179,808,794...179,951,428
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Ppp1cb
protein phosphatase 1 catalytic subunit beta
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of PPP1CB mRNA]
CTD
PMID:19030233
NCBI chr 6:23,958,813...23,992,841
Ensembl chr 6:23,960,998...23,992,824
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Ppp3ca
protein phosphatase 3 catalytic subunit alpha
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of PPP3CA mRNA]
CTD
PMID:19030233
NCBI chr 2:225,165,981...225,440,978
Ensembl chr 2:225,165,766...225,438,974
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Prkd3
protein kinase D3
multiple interactions affects expression
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of PRKD3 mRNA] Rimonabant affects the expression of PRKD3 mRNA
CTD
PMID:19030233
NCBI chr 6:16,032,507...16,108,444
Ensembl chr 6:16,032,585...16,108,443
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Prkn
parkin RBR E3 ubiquitin protein ligase
decreases response to substance multiple interactions
ISO EXP
PRKN results in decreased susceptibility to Rimonabant Rimonabant affects the reaction [PRKN mutant form affects the activity of TH protein]
CTD
PMID:15882845
NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555
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Prl
prolactin
multiple interactions increases expression
ISO EXP
Rimonabant inhibits the reaction [Dronabinol inhibits the reaction [[Medroxyprogesterone Acetate co-treated with Estradiol co-treated with Colforsin] results in increased expression of PRL mRNA]] Dronabinol affects the reaction [Rimonabant results in increased expression of PRL protein]; Rimonabant inhibits the reaction [Dronabinol results in decreased expression of PRL protein]
CTD
PMID:9825732 PMID:15099659 PMID:31154070
NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062
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Prpf40a
pre-mRNA processing factor 40 homolog A
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of PRPF40A mRNA]
CTD
PMID:19030233
NCBI chr 3:37,625,585...37,689,859
Ensembl chr 3:37,627,690...37,690,886
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Prps1
phosphoribosyl pyrophosphate synthetase 1
affects expression multiple interactions
ISO
Rimonabant affects the expression of PRPS1 mRNA Rimonabant inhibits the reaction [Dietary Fats results in increased expression of PRPS1 mRNA]
CTD
PMID:19030233
NCBI chr X:104,132,139...104,154,191
Ensembl chr X:104,132,141...104,154,187
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Ptbp3
polypyrimidine tract binding protein 3
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of PTBP3 mRNA]
CTD
PMID:19030233
NCBI chr 5:74,313,367...74,399,439
Ensembl chr 5:74,315,101...74,399,791
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Pten
phosphatase and tensin homolog
affects expression multiple interactions
EXP
Rimonabant affects the expression of PTEN mRNA [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone co-treated with Rimonabant] affects the expression of PTEN mRNA
CTD
PMID:32833042
NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838
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Ptges2
prostaglandin E synthase 2
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of PTGES2 mRNA]
CTD
PMID:19030233
NCBI chr 3:15,690,501...15,697,688
Ensembl chr 3:15,690,501...15,697,688
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Ptgs2
prostaglandin-endoperoxide synthase 2
multiple interactions
ISO
Rimonabant inhibits the reaction [forsythiaside inhibits the reaction [amyloid beta-protein (25-35) results in increased expression of PTGS2 protein]]; Rimonabant inhibits the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]]; Rimonabant inhibits the reaction [JZL 184 inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]]
CTD
PMID:26209559 PMID:30769029
NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
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Ptp4a1
protein tyrosine phosphatase 4A1
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of PTP4A1 mRNA]
CTD
PMID:19030233
NCBI chr 9:33,214,201...33,245,046
Ensembl chr 9:33,214,208...33,221,964
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Pyy
peptide YY
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of PYY mRNA]
CTD
PMID:19030233
NCBI chr10:87,061,155...87,062,278
Ensembl chr10:87,061,161...87,061,815
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Rac1
Rac family small GTPase 1
multiple interactions
ISO
Rimonabant inhibits the reaction [Ethanol promotes the reaction [EHMT2 protein binds to RAC1 promoter]]; Rimonabant inhibits the reaction [Ethanol results in decreased expression of RAC1 protein]
CTD
PMID:30143782
NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251
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Raf1
Raf-1 proto-oncogene, serine/threonine kinase
multiple interactions
ISO
Rimonabant inhibits the reaction [Dronabinol results in increased localization of RAF1 protein]; Rimonabant inhibits the reaction [methanandamide results in increased localization of RAF1 protein]
CTD
PMID:12834810
NCBI chr 4:148,679,534...148,740,265
Ensembl chr 4:148,679,530...148,740,317
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Ramp2
receptor activity modifying protein 2
affects expression multiple interactions
ISO
Rimonabant affects the expression of RAMP2 mRNA Rimonabant inhibits the reaction [Dietary Fats results in increased expression of RAMP2 mRNA]
CTD
PMID:19030233
NCBI chr10:86,187,366...86,190,692
Ensembl chr10:86,188,812...86,231,829
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Rbms1
RNA binding motif, single stranded interacting protein 1
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of RBMS1 mRNA]
CTD
PMID:19030233
NCBI chr 3:45,195,828...45,420,406
Ensembl chr 3:45,197,972...45,420,376
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Rbp4
retinol binding protein 4
decreases expression
ISO
rimonabant decreases expression of Rbp4 mRNA and protein in adipose tissue, aortic tissue and adipocytes
RGD
PMID:21585349
RGD:329853312
NCBI chr 1:235,893,917...235,901,315
Ensembl chr 1:235,893,917...235,901,399
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Rbpj
recombination signal binding protein for immunoglobulin kappa J region
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of RBPJ mRNA]
CTD
PMID:19030233
NCBI chr14:57,338,493...57,523,330
Ensembl chr14:57,338,507...57,523,353
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Rela
RELA proto-oncogene, NF-kB subunit
multiple interactions decreases expression
ISO
Rimonabant inhibits the reaction [JZL 184 inhibits the reaction [Sulfur Dioxide results in increased phosphorylation of RELA protein]] Rimonabant results in decreased expression of RELA protein
CTD
PMID:21373835 PMID:26209559
NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
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Rfng
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
multiple interactions affects expression
ISO
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of RFNG mRNA] Rimonabant affects the expression of RFNG mRNA
CTD
PMID:19030233
NCBI chr10:106,047,221...106,050,331
Ensembl chr10:106,047,221...106,050,345
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Rgs11
regulator of G-protein signaling 11
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of RGS11 mRNA]
CTD
PMID:19030233
NCBI chr10:15,222,804...15,231,062
Ensembl chr10:15,222,803...15,231,060
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Ripk1
receptor interacting serine/threonine kinase 1
multiple interactions
ISO
Rimonabant inhibits the reaction [Quetiapine Fumarate results in increased expression of RIPK1 protein]
CTD
PMID:31220554
NCBI chr17:30,839,639...30,871,824
Ensembl chr17:30,839,650...30,871,824
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Ripk3
receptor-interacting serine-threonine kinase 3
multiple interactions
ISO
Rimonabant inhibits the reaction [Quetiapine Fumarate results in increased expression of RIPK3 protein]
CTD
PMID:31220554
NCBI chr15:29,283,153...29,292,107
Ensembl chr15:29,283,145...29,292,121
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rnf141
ring finger protein 141
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of RNF141 mRNA]
CTD
PMID:19030233
NCBI chr 1:164,933,972...164,957,081
Ensembl chr 1:164,931,077...164,957,118
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Rnf185
ring finger protein 185
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of RNF185 mRNA]
CTD
PMID:19030233
NCBI chr14:78,292,517...78,329,832
Ensembl chr14:78,292,516...78,329,864
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Rnf19a
ring finger protein 19A, RBR E3 ubiquitin protein ligase
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of RNF19A mRNA]
CTD
PMID:19030233
NCBI chr 7:67,425,833...67,465,214
Ensembl chr 7:67,425,837...67,465,222
G
Rnf2
ring finger protein 2
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of RNF2 mRNA]
CTD
PMID:19030233
NCBI chr13:63,553,964...63,584,047
Ensembl chr13:63,554,862...63,583,099
G
Rnf6
ring finger protein 6
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of RNF6 mRNA]
CTD
PMID:19030233
NCBI chr12:8,816,797...8,826,870
Ensembl chr12:8,816,833...8,826,847
G
Rp9
RP9, pre-mRNA splicing factor
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of RP9 mRNA]
CTD
PMID:19030233
NCBI chr 8:20,955,447...21,005,225
Ensembl chr 8:20,941,362...21,005,175
G
Rpf2
ribosome production factor 2 homolog
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of RPF2 mRNA]
CTD
PMID:19030233
NCBI chr20:43,630,003...43,651,477
Ensembl chr20:43,629,951...43,651,509
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Rpl18
ribosomal protein L18
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of RPL18 mRNA]
CTD
PMID:19030233
NCBI chr 1:96,188,811...96,191,452
Ensembl chr 1:96,188,112...96,191,452
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Rpl28
ribosomal protein L28
affects expression multiple interactions
ISO
Rimonabant affects the expression of RPL28 mRNA Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of RPL28 mRNA]
CTD
PMID:19030233
NCBI chr 1:69,052,148...69,054,735
Ensembl chr 1:69,053,203...69,055,032
G
Rpl41
ribosomal protein L41
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of RPL41 mRNA]
CTD
PMID:19030233
NCBI chr 7:977,885...978,965
G
Rps10
ribosomal protein S10
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of RPS10 mRNA]
CTD
PMID:19030233
NCBI chr20:5,694,313...5,698,922
Ensembl chr20:5,694,313...5,699,044 Ensembl chr 6:5,694,313...5,699,044
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Rps15
ribosomal protein S15
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of RPS15 mRNA]
CTD
PMID:19030233
NCBI chr 7:9,416,003...9,417,442
Ensembl chr 7:9,416,004...9,417,450
G
Rps28
ribosomal protein S28
affects expression
ISO
Rimonabant affects the expression of RPS28 mRNA
CTD
PMID:19030233
NCBI chr 7:14,607,801...14,609,170
Ensembl chr 7:14,607,801...14,609,170 Ensembl chr16:14,607,801...14,609,170
G
Rps6
ribosomal protein S6
decreases phosphorylation
ISO
Rimonabant results in decreased phosphorylation of RPS6 protein
CTD
PMID:30687088
NCBI chr 5:101,371,716...101,374,576
Ensembl chr 5:101,371,136...101,374,602 Ensembl chr 5:101,371,136...101,374,602
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Rps8
ribosomal protein S8
affects expression multiple interactions
ISO
Rimonabant affects the expression of RPS8 mRNA Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of RPS8 mRNA]
CTD
PMID:19030233
NCBI chr 5:130,630,362...130,632,932
Ensembl chr 5:130,629,716...130,633,268
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Rras2
RAS related 2
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of RRAS2 mRNA]
CTD
PMID:19030233
NCBI chr 1:168,233,693...168,303,111
Ensembl chr 1:168,233,693...168,303,111
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Rxrb
retinoid X receptor beta
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of RXRB mRNA]
CTD
PMID:19030233
NCBI chr20:4,816,813...4,823,267
Ensembl chr20:4,816,815...4,828,773
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Ryk
receptor-like tyrosine kinase
affects expression multiple interactions
ISO
Rimonabant affects the expression of RYK mRNA Rimonabant inhibits the reaction [Dietary Fats results in increased expression of RYK mRNA]
CTD
PMID:19030233
NCBI chr 8:103,419,338...103,492,083
Ensembl chr 8:103,419,275...103,491,698
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Scarb1
scavenger receptor class B, member 1
increases expression
ISO
Rimonabant results in increased expression of SCARB1 mRNA
CTD
PMID:20110567
NCBI chr12:31,296,143...31,362,649
Ensembl chr12:31,296,156...31,362,647
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Scd
stearoyl-CoA desaturase
decreases expression
ISO
Rimonabant results in decreased expression of SCD1 mRNA
CTD
PMID:20110567
NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
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Scd2
stearoyl-Coenzyme A desaturase 2
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of SCD2 mRNA]
CTD
PMID:19030233
NCBI chr 1:243,169,171...243,182,231
Ensembl chr 1:243,169,236...243,182,232
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Scoc
short coiled-coil protein
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of SCOC mRNA]
CTD
PMID:19030233
NCBI chr19:24,659,651...24,689,237
Ensembl chr19:24,659,651...24,693,217
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Sec62
SEC62 homolog, preprotein translocation factor
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of SEC62 mRNA]
CTD
PMID:19030233
NCBI chr 2:112,570,810...112,598,198
Ensembl chr 2:112,570,819...112,601,814
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Sec63
SEC63 homolog, protein translocation regulator
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of SEC63 mRNA]
CTD
PMID:19030233
NCBI chr20:46,245,101...46,314,055
Ensembl chr20:46,245,101...46,314,055
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Sema3c
semaphorin 3C
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of SEMA3C mRNA]
CTD
PMID:19030233
NCBI chr 4:17,583,212...17,747,234
Ensembl chr 4:17,583,212...17,746,534
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Sepsecs
Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase
affects expression
ISO
Rimonabant affects the expression of SEPSECS mRNA
CTD
PMID:19030233
NCBI chr14:58,311,484...58,341,745
Ensembl chr14:58,311,499...58,341,740
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Septin2
septin 2
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of SEPTIN2 mRNA]
CTD
PMID:19030233
NCBI chr 9:94,018,141...94,051,386
Ensembl chr 9:94,018,208...94,051,386
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Septin6
septin 6
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of SEPTIN6 mRNA]
CTD
PMID:19030233
NCBI chr X:116,153,255...116,230,334
Ensembl chr X:116,153,255...116,230,115
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Serpinb6a
serpin family B member 6A
multiple interactions affects expression
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of SERPINB6A mRNA] Rimonabant affects the expression of SERPINB6A mRNA
CTD
PMID:19030233
NCBI chr17:30,871,468...30,989,703
Ensembl chr17:30,871,468...31,014,427
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Serpine1
serpin family E member 1
decreases expression
EXP
Rimonabant results in decreased expression of SERPINE1 protein
CTD
PMID:17882151
NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
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Sestd1
SEC14 and spectrin domain containing 1
multiple interactions affects expression
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of SESTD1 mRNA] Rimonabant affects the expression of SESTD1 mRNA
CTD
PMID:19030233
NCBI chr 3:62,123,590...62,220,759
Ensembl chr 3:62,129,887...62,220,546
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Sgta
small glutamine rich tetratricopeptide repeat co-chaperone alpha
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of SGTA mRNA]
CTD
PMID:19030233
NCBI chr 7:8,653,681...8,670,460
Ensembl chr 7:8,653,778...8,670,458
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Sh3bgrl1
SH3 domain binding glutamate rich protein like 1
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of SH3BGRL mRNA]
CTD
PMID:19030233
NCBI chr X:74,167,029...74,263,783
Ensembl chr X:74,166,871...74,263,783
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Sipa1l1
signal-induced proliferation-associated 1 like 1
multiple interactions affects expression
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of SIPA1L1 mRNA] Rimonabant affects the expression of SIPA1L1 mRNA
CTD
PMID:19030233
NCBI chr 6:101,839,351...102,118,408
Ensembl chr 6:101,839,404...102,116,950
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Slc2a4
solute carrier family 2 member 4
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of SLC2A4 mRNA]
CTD
PMID:19030233
NCBI chr10:54,666,015...54,671,581
Ensembl chr10:54,666,015...54,671,565
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Slc39a10
solute carrier family 39 member 10
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of SLC39A10 mRNA]
CTD
PMID:19030233
NCBI chr 9:54,836,841...54,960,325
Ensembl chr 9:54,876,141...54,960,325
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Slc39a8
solute carrier family 39 member 8
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of SLC39A8 mRNA]
CTD
PMID:19030233
NCBI chr 2:224,171,787...224,319,326
Ensembl chr 2:224,256,654...224,319,129
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Smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of SMARCA2 mRNA]
CTD
PMID:19030233
NCBI chr 1:224,191,125...224,358,640
Ensembl chr 1:224,191,125...224,358,684
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Socs1
suppressor of cytokine signaling 1
decreases expression
EXP
Rimonabant results in decreased expression of SOCS1 mRNA
CTD
PMID:30365523
NCBI chr10:4,882,651...4,884,342
Ensembl chr10:4,882,560...4,884,383
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Socs3
suppressor of cytokine signaling 3
decreases expression
EXP
Rimonabant results in decreased expression of SOCS3 mRNA
CTD
PMID:30365523
NCBI chr10:103,193,909...103,197,322
Ensembl chr10:103,193,537...103,197,787
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Sorbs2
sorbin and SH3 domain containing 2
affects expression
ISO
Rimonabant affects the expression of SORBS2 mRNA
CTD
PMID:19030233
NCBI chr16:46,435,220...46,748,743
Ensembl chr16:46,435,237...46,626,514
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Sparc
secreted protein acidic and cysteine rich
multiple interactions affects expression
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of SPARC mRNA] Rimonabant affects the expression of SPARC mRNA
CTD
PMID:19030233
NCBI chr10:39,516,394...39,538,252
Ensembl chr10:39,516,406...39,538,396
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Sptbn1
spectrin, beta, non-erythrocytic 1
multiple interactions affects expression
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of SPTBN1 mRNA] Rimonabant affects the expression of SPTBN1 mRNA
CTD
PMID:19030233
NCBI chr14:103,841,713...104,016,900
Ensembl chr14:103,842,684...104,008,507
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Src
SRC proto-oncogene, non-receptor tyrosine kinase
multiple interactions
ISO
Rimonabant inhibits the reaction [HU 211 results in increased phosphorylation of SRC protein]
CTD
PMID:16046413
NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
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Srp72
signal recognition particle 72
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of SRP72 mRNA]
CTD
PMID:19030233
NCBI chr14:31,168,175...31,195,717
Ensembl chr14:31,168,293...31,195,729
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St3gal6
ST3 beta-galactoside alpha-2,3-sialyltransferase 6
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ST3GAL6 mRNA]
CTD
PMID:19030233
NCBI chr11:42,061,282...42,121,801
Ensembl chr11:42,077,621...42,121,776
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Stat3
signal transducer and activator of transcription 3
multiple interactions
ISO
Rimonabant inhibits the reaction [HU 211 results in increased phosphorylation of STAT3 protein]
CTD
PMID:16046413
NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
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Stat6
signal transducer and activator of transcription 6
multiple interactions
ISO
[MIR466J mRNA co-treated with Rimonabant] affects the expression of STAT6 mRNA; Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of STAT6 mRNA]
CTD
PMID:30910812
NCBI chr 7:63,480,229...63,497,551
Ensembl chr 7:63,479,642...63,498,495
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Stim2
stromal interaction molecule 2
multiple interactions affects expression
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of STIM2 mRNA] Rimonabant affects the expression of STIM2 mRNA
CTD
PMID:19030233
NCBI chr14:56,878,428...57,004,405
Ensembl chr14:56,878,645...57,004,179
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Strn4
striatin 4
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of STRN4 mRNA]
CTD
PMID:19030233
NCBI chr 1:77,482,267...77,511,862
Ensembl chr 1:77,482,094...77,511,858
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Tcea1
transcription elongation factor A1
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of TCEA1 mRNA]
CTD
PMID:19030233
NCBI chr 5:14,631,454...14,668,769
Ensembl chr 5:14,631,454...14,668,745 Ensembl chr15:14,631,454...14,668,745
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Tgfb1
transforming growth factor, beta 1
decreases expression
EXP
Rimonabant results in decreased expression of TGFB1 mRNA
CTD
PMID:30365523
NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
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Tgif2
TGFB-induced factor homeobox 2
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of TGIF2 mRNA]
CTD
PMID:19030233
NCBI chr 3:145,333,152...145,348,599
Ensembl chr 3:145,333,418...145,348,596
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Th
tyrosine hydroxylase
multiple interactions increases activity
EXP
Rimonabant affects the reaction [PRKN mutant form affects the activity of TH protein]; Rimonabant inhibits the reaction [Dronabinol results in increased activity of TH protein] Rimonabant results in increased activity of TH protein
CTD
PMID:9188039 PMID:10700552 PMID:15882845
NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767
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Thy1
Thy-1 cell surface antigen
multiple interactions
EXP
Rimonabant inhibits the reaction [methanandamide affects the expression of THY1 mRNA]
CTD
PMID:17591864
NCBI chr 8:44,389,495...44,394,688
Ensembl chr 8:44,389,513...44,394,659
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Timp1
TIMP metallopeptidase inhibitor 1
decreases expression
EXP
Rimonabant results in decreased expression of TIMP1 mRNA
CTD
PMID:21863215 PMID:30365523
NCBI chr X:1,212,969...1,217,714
Ensembl chr X:1,212,972...1,217,664
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Tmed7
transmembrane p24 trafficking protein 7
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of TMED7 mRNA]
CTD
PMID:19030233
NCBI chr18:39,318,564...39,325,640
Ensembl chr18:39,297,351...39,325,640
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Tnf
tumor necrosis factor
multiple interactions decreases expression
ISO EXP
Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased expression of TNF]; Rimonabant inhibits the reaction [forsythiaside inhibits the reaction [amyloid beta-protein (25-35) results in increased expression of TNF protein]] Rimonabant results in decreased expression of TNF mRNA
CTD
PMID:20110567 PMID:30365523 PMID:30769029 PMID:32832534
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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Tomm20
translocase of outer mitochondrial membrane 20
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of TOMM20 mRNA]
CTD
PMID:19030233
NCBI chr19:54,925,197...54,935,188
Ensembl chr19:54,923,402...54,935,198
G
Tpm4
tropomyosin 4
affects expression multiple interactions
ISO
Rimonabant affects the expression of TPM4 mRNA Rimonabant inhibits the reaction [Dietary Fats results in increased expression of TPM4 mRNA]
CTD
PMID:19030233
NCBI chr16:17,684,415...17,698,456
Ensembl chr16:17,683,195...17,705,984
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Trpv1
transient receptor potential cation channel, subfamily V, member 1
multiple interactions
ISO
Rimonabant inhibits the reaction [anandamide binds to and results in increased activity of TRPV1 protein]; Rimonabant inhibits the reaction [Capsaicin binds to and results in increased activity of TRPV1 protein]; Rimonabant inhibits the reaction [N-(4-hydroxyphenyl)arachidonylamide binds to and results in increased activity of TRPV1 protein]
CTD
PMID:11278420
NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513
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Tsen2
tRNA splicing endonuclease subunit 2
affects expression multiple interactions
ISO
Rimonabant affects the expression of TSEN2 mRNA Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of TSEN2 mRNA]
CTD
PMID:19030233
NCBI chr 4:148,602,805...148,638,219
Ensembl chr 4:148,602,863...148,638,215
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Tspan5
tetraspanin 5
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of TSPAN5 mRNA]
CTD
PMID:19030233
NCBI chr 2:227,294,180...227,469,361
Ensembl chr 2:227,294,217...227,465,664
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Txnrd1
thioredoxin reductase 1
increases expression
EXP
Rimonabant results in increased expression of TXNRD1 mRNA
CTD
PMID:30365523
NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863
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Unc5b
unc-5 netrin receptor B
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of UNC5B mRNA]
CTD
PMID:30910812
NCBI chr20:28,697,726...28,764,474
Ensembl chr20:28,697,726...28,764,537
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Usp46
ubiquitin specific peptidase 46
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of USP46 mRNA]
CTD
PMID:19030233
NCBI chr14:34,150,055...34,219,227
Ensembl chr14:34,150,004...34,219,227
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Usp48
ubiquitin specific peptidase 48
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of USP48 mRNA]
CTD
PMID:19030233
NCBI chr 5:149,800,189...149,867,838
Ensembl chr 5:149,800,179...149,867,719
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Vcam1
vascular cell adhesion molecule 1
multiple interactions decreases expression
ISO
Rimonabant inhibits the reaction [Glucose results in increased expression of VCAM1 protein] Rimonabant results in decreased expression of VCAM1 protein
CTD
PMID:21373835
NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
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Vcl
vinculin
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of VCL mRNA]
CTD
PMID:19030233
NCBI chr15:3,265,776...3,355,586
Ensembl chr15:3,265,815...3,355,606
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Vegfa
vascular endothelial growth factor A
multiple interactions
ISO
Rimonabant inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in decreased expression of and results in decreased secretion of VEGFA protein]
CTD
PMID:15313899
NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
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Vim
vimentin
multiple interactions affects expression
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of VIM mRNA] Rimonabant affects the expression of VIM mRNA
CTD
PMID:19030233
NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
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Vldlr
very low density lipoprotein receptor
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of VLDLR mRNA]
CTD
PMID:19030233
NCBI chr 1:224,813,539...224,850,400
Ensembl chr 1:224,814,377...224,845,920
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Wdr26
WD repeat domain 26
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of WDR26 mRNA]
CTD
PMID:19030233
NCBI chr13:92,930,282...92,972,061
Ensembl chr13:92,930,285...92,977,295
G
Wdr7
WD repeat domain 7
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of WDR7 mRNA]
CTD
PMID:19030233
NCBI chr18:57,165,482...57,448,568
Ensembl chr18:57,165,488...57,448,540
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Wsb1
WD repeat and SOCS box-containing 1
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of WSB1 mRNA]
CTD
PMID:19030233
NCBI chr10:64,202,761...64,219,039
Ensembl chr10:64,202,763...64,219,019
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Wwp1
WW domain containing E3 ubiquitin protein ligase 1
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of WWP1 mRNA]
CTD
PMID:19030233
NCBI chr 5:33,092,379...33,185,887
Ensembl chr 5:33,098,494...33,186,046
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Wwtr1
WW domain containing transcription regulator 1
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of WWTR1 mRNA]
CTD
PMID:19030233
NCBI chr 2:141,651,159...141,766,919
Ensembl chr 2:141,648,108...141,766,968
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Xbp1
X-box binding protein 1
increases expression multiple interactions
ISO
Rimonabant results in increased expression of XBP1 mRNA [Rimonabant co-treated with SR 144528] inhibits the reaction [Dronabinol results in increased expression of XBP1 mRNA alternative form]; Gemcitabine promotes the reaction [Rimonabant results in increased expression of XBP1 mRNA]
CTD
PMID:21525939 PMID:31054322
NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693
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Zdhhc2
zinc finger DHHC-type palmitoyltransferase 2
affects expression multiple interactions
ISO
Rimonabant affects the expression of ZDHHC2 mRNA Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ZDHHC2 mRNA]
CTD
PMID:19030233
NCBI chr16:51,808,465...51,878,060
Ensembl chr16:51,808,468...51,878,060
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Zdhhc7
zinc finger DHHC-type palmitoyltransferase 7
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of ZDHHC7 mRNA]
CTD
PMID:19030233
NCBI chr19:48,139,309...48,156,673
Ensembl chr19:48,139,527...48,156,673
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Zhx1
zinc fingers and homeoboxes 1
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ZHX1 mRNA]
CTD
PMID:19030233
NCBI chr 7:89,582,363...89,611,337
Ensembl chr 7:89,582,243...89,611,264
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Znrf2
zinc and ring finger 2
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ZNRF2 mRNA]
CTD
PMID:19030233
NCBI chr 4:83,950,406...84,032,676
Ensembl chr 4:83,949,309...84,027,818
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Zwilch
zwilch kinetochore protein
affects expression
ISO
Rimonabant affects the expression of ZWILCH mRNA
CTD
PMID:19030233
NCBI chr 8:64,638,401...64,670,911
Ensembl chr 8:64,637,672...64,675,916
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