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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:etonogestrel
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Accession:CHEBI:50777 term browser browse the term
Definition:A terminal acetylenic compound that has formula C22H28O2.
Synonyms:exact_synonym: 17alpha-ethynyl-17beta-hydroxy-11-methylidene-18a-homo-estr-4-en-3-one
 related_synonym: 3-Ketodesogestrel;   3-Oxodesogestrel;   Formula=C22H28O2;   Implanon;   InChI=1S/C22H28O2/c1-4-21-13-14(3)20-17-9-7-16(23)12-15(17)6-8-18(20)19(21)10-11-22(21,24)5-2/h2,12,17-20,24H,3-4,6-11,13H2,1H3/t17-,18-,19-,20+,21-,22-/m0/s1;   InChIKey=GCKFUYQCUCGESZ-BPIQYHPVSA-N;   SMILES=[H][C@]12CCC(=O)C=C1CC[C@@]1([H])[C@]3([H])CC[C@@](O)(C#C)[C@@]3(CC)CC(=C)[C@]21[H];   etonogestrelum
 xref: Beilstein:4237530;   CAS:54048-10-1;   DrugBank:DB00294;   Drug_Central:1110;   KEGG:D04104
 xref_mesh: MESH:C044815
 xref: Patent:EP51762;   Patent:US4371529


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etonogestrel term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 affects metabolic processing ISO CYP3A4 protein affects the metabolism of etonogestrel CTD PMID:15963096 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G F2 coagulation factor II, thrombin multiple interactions EXP etonogestrel promotes the reaction [F2 protein results in increased expression of F3 mRNA] CTD PMID:11733402 NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486 		JBrowse link
G F2r coagulation factor II (thrombin) receptor multiple interactions
increases expression		 EXP Mifepristone inhibits the reaction [etonogestrel results in increased expression of F2R mRNA] CTD PMID:11733402 NCBI chr 2:26,869,343...26,885,856
Ensembl chr 2:26,868,404...26,885,870 		JBrowse link
G F3 coagulation factor III, tissue factor multiple interactions EXP etonogestrel promotes the reaction [F2 protein results in increased expression of F3 mRNA] CTD PMID:11733402 NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668 		JBrowse link
G Pgr progesterone receptor increases expression ISO etonogestrel results in increased expression of PGR protein CTD PMID:11041225 NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19921
    chemical entity 19919
      group 19877
        organic group 18971
          3-oxo-Delta(4)-steroid group 9165
            3-oxo-Delta(4) steroid 9165
              etonogestrel 5
Path 2
Term Annotations click to browse term
  CHEBI ontology 19921
    subatomic particle 19919
      composite particle 19919
        hadron 19919
          baryon 19919
            nucleon 19919
              atomic nucleus 19919
                atom 19919
                  main group element atom 19867
                    p-block element atom 19867
                      carbon group element atom 19812
                        carbon atom 19807
                          organic molecular entity 19807
                            organic group 18971
                              organic divalent group 18952
                                organodiyl group 18952
                                  carbonyl group 18905
                                    carbonyl compound 18905
                                      ketone 17193
                                        oxo steroid 10543
                                          3-oxo steroid 9929
                                            3-oxo-Delta(4) steroid 9165
                                              etonogestrel 5
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