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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:etonogestrel
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Accession:CHEBI:50777 term browser browse the term
Definition:A terminal acetylenic compound that has formula C22H28O2.
Synonyms:exact_synonym: 17alpha-ethynyl-17beta-hydroxy-11-methylidene-18a-homo-estr-4-en-3-one
 related_synonym: 3-Ketodesogestrel;   3-Oxodesogestrel;   Formula=C22H28O2;   Implanon;   InChI=1S/C22H28O2/c1-4-21-13-14(3)20-17-9-7-16(23)12-15(17)6-8-18(20)19(21)10-11-22(21,24)5-2/h2,12,17-20,24H,3-4,6-11,13H2,1H3/t17-,18-,19-,20+,21-,22-/m0/s1;   InChIKey=GCKFUYQCUCGESZ-BPIQYHPVSA-N;   SMILES=[H][C@]12CCC(=O)C=C1CC[C@@]1([H])[C@]3([H])CC[C@@](O)(C#C)[C@@]3(CC)CC(=C)[C@]21[H];   etonogestrelum
 xref: Beilstein:4237530;   CAS:54048-10-1;   DrugBank:DB00294;   Drug_Central:1110;   KEGG:D04104
 xref_mesh: MESH:C044815
 xref: Patent:EP51762;   Patent:US4371529



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etonogestrel term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 affects metabolic processing ISO CYP3A4 protein affects the metabolism of etonogestrel CTD PMID:15963096 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G F2 coagulation factor II multiple interactions EXP etonogestrel promotes the reaction [F2 protein results in increased expression of F3 mRNA] CTD PMID:11733402 NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486
JBrowse link
G F2r coagulation factor II (thrombin) receptor multiple interactions
increases expression
EXP Mifepristone inhibits the reaction [etonogestrel results in increased expression of F2R mRNA] CTD PMID:11733402 NCBI chr 2:26,869,343...26,885,856
Ensembl chr 2:26,868,404...26,885,870
JBrowse link
G F3 coagulation factor III, tissue factor multiple interactions EXP etonogestrel promotes the reaction [F2 protein results in increased expression of F3 mRNA] CTD PMID:11733402 NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668
JBrowse link
G Pgr progesterone receptor increases expression ISO etonogestrel results in increased expression of PGR protein CTD PMID:11041225 NCBI chr 8:6,073,216...6,131,552
Ensembl chr 8:6,072,673...6,131,344
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20056
    chemical entity 20055
      group 19986
        organic group 18961
          3-oxo-Delta(4)-steroid group 9160
            3-oxo-Delta(4) steroid 9160
              etonogestrel 5
Path 2
Term Annotations click to browse term
  CHEBI ontology 20056
    subatomic particle 20054
      composite particle 20054
        hadron 20054
          baryon 20054
            nucleon 20054
              atomic nucleus 20054
                atom 20054
                  main group element atom 19956
                    p-block element atom 19956
                      carbon group element atom 19882
                        carbon atom 19875
                          organic molecular entity 19875
                            organic group 18961
                              organic divalent group 18947
                                organodiyl group 18947
                                  carbonyl group 18900
                                    carbonyl compound 18900
                                      ketone 17091
                                        oxo steroid 10321
                                          3-oxo steroid 9924
                                            3-oxo-Delta(4) steroid 9160
                                              etonogestrel 5
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