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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:etonogestrel
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Accession:CHEBI:50777 term browser browse the term
Definition:A terminal acetylenic compound that has formula C22H28O2.
Synonyms:exact_synonym: 17alpha-ethynyl-17beta-hydroxy-11-methylidene-18a-homo-estr-4-en-3-one
 related_synonym: 3-Ketodesogestrel;   3-Oxodesogestrel;   Formula=C22H28O2;   Implanon;   InChI=1S/C22H28O2/c1-4-21-13-14(3)20-17-9-7-16(23)12-15(17)6-8-18(20)19(21)10-11-22(21,24)5-2/h2,12,17-20,24H,3-4,6-11,13H2,1H3/t17-,18-,19-,20+,21-,22-/m0/s1;   InChIKey=GCKFUYQCUCGESZ-BPIQYHPVSA-N;   SMILES=[H][C@]12CCC(=O)C=C1CC[C@@]1([H])[C@]3([H])CC[C@@](O)(C#C)[C@@]3(CC)CC(=C)[C@]21[H];   etonogestrelum
 xref: Beilstein:4237530;   CAS:54048-10-1;   DrugBank:DB00294;   Drug_Central:1110;   KEGG:D04104
 xref_mesh: MESH:C044815
 xref: Patent:EP51762;   Patent:US4371529


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etonogestrel term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 affects metabolic processing ISO CYP3A4 protein affects the metabolism of etonogestrel CTD PMID:15963096 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G F2 coagulation factor II multiple interactions EXP etonogestrel promotes the reaction [F2 protein results in increased expression of F3 mRNA] CTD PMID:11733402 NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486
JBrowse link
G F2r coagulation factor II (thrombin) receptor multiple interactions
increases expression
EXP Mifepristone inhibits the reaction [etonogestrel results in increased expression of F2R mRNA] CTD PMID:11733402 NCBI chr 2:26,869,343...26,885,856
Ensembl chr 2:26,868,404...26,885,870
JBrowse link
G F3 coagulation factor III, tissue factor multiple interactions EXP etonogestrel promotes the reaction [F2 protein results in increased expression of F3 mRNA] CTD PMID:11733402 NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668
JBrowse link
G Pgr progesterone receptor increases expression ISO etonogestrel results in increased expression of PGR protein CTD PMID:11041225 NCBI chr 8:6,073,216...6,131,552
Ensembl chr 8:6,072,673...6,131,344
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19821
    chemical entity 19821
      group 19741
        organic group 18737
          3-oxo-Delta(4)-steroid group 8420
            3-oxo-Delta(4) steroid 8420
              etonogestrel 5
Path 2
Term Annotations click to browse term
  CHEBI ontology 19821
    subatomic particle 19819
      composite particle 19819
        hadron 19819
          baryon 19819
            nucleon 19819
              atomic nucleus 19819
                atom 19819
                  main group element atom 19716
                    p-block element atom 19716
                      carbon group element atom 19640
                        carbon atom 19630
                          organic molecular entity 19630
                            organic group 18737
                              organic divalent group 18728
                                organodiyl group 18728
                                  carbonyl group 18675
                                    carbonyl compound 18675
                                      ketone 16923
                                        oxo steroid 9720
                                          3-oxo steroid 9279
                                            3-oxo-Delta(4) steroid 8420
                                              etonogestrel 5
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