|
|
| G
|
Acta2
|
actin alpha 2, smooth muscle
|
increases expression multiple interactions
|
ISO
|
Desoxycorticosterone results in increased expression of ACTA2 mRNA; Desoxycorticosterone results in increased expression of ACTA2 protein Rotenone inhibits the reaction [Desoxycorticosterone results in increased expression of ACTA2 protein]
|
CTD |
PMID:17596522 |
|
NCBI chr 1:241,159,723...241,172,503
Ensembl chr 1:241,159,724...241,172,503
|
|
| G
|
Agt
|
angiotensinogen
|
increases activity
|
EXP
|
Desoxycorticosterone results in increased activity of AGT protein
|
CTD |
PMID:9087624 |
|
NCBI chr19:69,426,540...69,447,017
Ensembl chr19:69,421,638...69,446,944
|
|
| G
|
Akr1c3
|
aldo-keto reductase family 1, member C3
|
increases metabolic processing
|
ISO
|
AKR1C18 protein results in increased metabolism of Desoxycorticosterone
|
CTD |
PMID:17122075 |
|
NCBI chr17:71,020,884...71,037,779
Ensembl chr17:70,970,900...71,048,438
|
|
| G
|
Ar
|
androgen receptor
|
multiple interactions
|
ISO
|
Desoxycorticosterone binds to and results in increased activity of AR protein mutant form
|
CTD |
PMID:11956172 |
|
NCBI chr X:67,135,317...67,304,476
Ensembl chr X:67,135,317...67,304,467
|
|
| G
|
Bax
|
BCL2 associated X, apoptosis regulator
|
multiple interactions
|
EXP
|
[Desoxycorticosterone co-treated with Sodium Chloride] results in increased expression of BAX protein; acetovanillone inhibits the reaction [[Desoxycorticosterone co-treated with Sodium Chloride] results in increased expression of BAX protein]; atrasentan inhibits the reaction [[Desoxycorticosterone co-treated with Sodium Chloride] results in increased expression of BAX protein]
|
CTD |
PMID:22431579 |
|
NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429
|
|
| G
|
Bcl2
|
BCL2, apoptosis regulator
|
multiple interactions
|
EXP
|
[Desoxycorticosterone co-treated with Sodium Chloride] results in decreased expression of BCL2 protein; acetovanillone inhibits the reaction [[Desoxycorticosterone co-treated with Sodium Chloride] results in decreased expression of BCL2 protein]; Atrasentan inhibits the reaction [[Desoxycorticosterone co-treated with Sodium Chloride] results in decreased expression of BCL2 protein]
|
CTD |
PMID:22431579 |
|
NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900
|
|
| G
|
Cat
|
catalase
|
multiple interactions
|
EXP
|
CAT protein results in increased susceptibility to [tert-Butylhydroperoxide co-treated with Desoxycorticosterone co-treated with tempol]
|
CTD |
PMID:12646410 |
|
NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526
|
|
| G
|
Ccl2
|
C-C motif chemokine ligand 2
|
multiple interactions
|
EXP
|
[Desoxycorticosterone co-treated with Sodium Chloride, Dietary] results in increased expression of CCL2 mRNA; [Desoxycorticosterone co-treated with Sodium Chloride, Dietary] results in increased expression of CCL2 protein; Mineralocorticoid Receptor Antagonists inhibits the reaction [[Desoxycorticosterone co-treated with Sodium Chloride, Dietary] results in increased expression of CCL2 protein]
|
CTD |
PMID:21135038 |
|
NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875
|
|
| G
|
Cdh1
|
cadherin 1
|
decreases expression multiple interactions
|
ISO
|
Desoxycorticosterone results in decreased expression of CDH1 mRNA; Desoxycorticosterone results in decreased expression of CDH1 protein Rotenone inhibits the reaction [Desoxycorticosterone results in decreased expression of CDH1 protein]
|
CTD |
PMID:17596522 |
|
NCBI chr19:51,402,178...51,471,572
Ensembl chr19:51,402,034...51,471,565
|
|
| G
|
Cyba
|
cytochrome b-245 alpha chain
|
increases expression multiple interactions
|
EXP
|
Desoxycorticosterone results in increased expression of CYBA mRNA; Desoxycorticosterone results in increased expression of CYBA protein [Desoxycorticosterone co-treated with Sodium Chloride] results in increased expression of CYBA protein
|
CTD |
PMID:16271043 PMID:22431579 |
|
NCBI chr19:50,487,598...50,495,669
Ensembl chr19:67,396,143...67,404,214
|
|
| G
|
Cyp11b2
|
cytochrome P450, family 11, subfamily b, polypeptide 2
|
affects metabolic processing multiple interactions increases chemical synthesis
|
ISO EXP
|
CYP11B1 protein affects the metabolism of Desoxycorticosterone Plant Extracts inhibits the reaction [Desoxycorticosterone binds to CYP11B1 protein] CYP11B1 protein results in increased chemical synthesis of Desoxycorticosterone
|
CTD |
PMID:15666820 PMID:16054388 PMID:19900470 |
|
NCBI chr 7:108,719,349...108,726,024
Ensembl chr 7:108,719,349...108,725,763
|
|
| G
|
Cyp11b3
|
cytochrome P450, family 11, subfamily b, polypeptide 3
|
affects metabolic processing multiple interactions increases hydroxylation
|
ISO
|
CYP11B2 protein affects the metabolism of Desoxycorticosterone [CYP11B2 protein results in increased hydroxylation of Desoxycorticosterone] which results in increased chemical synthesis of Corticosterone
|
CTD |
PMID:15985365 PMID:21384875 |
|
NCBI chr 7:108,689,319...108,694,808
Ensembl chr 7:108,689,165...108,694,921
|
|
| G
|
Edn1
|
endothelin 1
|
multiple interactions increases expression
|
EXP
|
[Sodium Chloride, Dietary co-treated with Desoxycorticosterone] results in increased expression of EDN1 mRNA; [Sodium Chloride, Dietary co-treated with Desoxycorticosterone] results in increased expression of EDN1 protein; Clofibrate inhibits the reaction [Desoxycorticosterone results in increased expression of EDN1 protein]; Mibefradil inhibits the reaction [[Sodium Chloride, Dietary co-treated with Desoxycorticosterone] results in increased expression of EDN1 mRNA] Desoxycorticosterone results in increased expression of EDN1; Desoxycorticosterone results in increased expression of EDN1 protein
|
CTD |
PMID:1860718 PMID:8934362 PMID:12600921 PMID:16054168 |
|
NCBI chr17:22,660,799...22,666,687
Ensembl chr17:22,660,799...22,666,687
|
|
| G
|
Ednra
|
endothelin receptor type A
|
multiple interactions affects response to substance
|
EXP
|
[5-(dimethylamino)-N-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesulfonamide binds to and results in decreased activity of EDNRA protein] inhibits the reaction [Desoxycorticosterone results in increased chemical synthesis of Reactive Oxygen Species]; [Desoxycorticosterone co-treated with Sodium Chloride] results in increased expression of EDNRA protein EDNRA protein affects the susceptibility to Desoxycorticosterone
|
CTD |
PMID:12600921 PMID:16271043 PMID:22431579 |
|
NCBI chr19:47,137,360...47,207,961
Ensembl chr19:47,137,771...47,201,284
|
|
| G
|
Egf
|
epidermal growth factor
|
multiple interactions increases response to substance
|
EXP
|
4,5-dianilinophthalimide inhibits the reaction [EGF protein results in increased susceptibility to Desoxycorticosterone]; RTKI cpd inhibits the reaction [EGF protein results in increased susceptibility to Desoxycorticosterone]
|
CTD |
PMID:11751714 |
|
NCBI chr 2:220,893,660...220,976,331
Ensembl chr 2:220,893,660...220,976,297
|
|
| G
|
Ep300
|
E1A binding protein p300
|
multiple interactions
|
EXP
|
Desoxycorticosterone promotes the reaction [EP300 protein binds to SULT1A1 promoter]; Desoxycorticosterone promotes the reaction [EP300 protein binds to TAT promoter]
|
CTD |
PMID:22465009 |
|
NCBI chr 7:114,987,857...115,058,652
Ensembl chr 7:114,946,982...115,058,574
|
|
| G
|
Fabp3
|
fatty acid binding protein 3
|
multiple interactions
|
EXP
|
[Desoxycorticosterone co-treated with Sodium Chloride, Dietary] results in increased expression of FABP3 protein; Mineralocorticoid Receptor Antagonists inhibits the reaction [[Desoxycorticosterone co-treated with Sodium Chloride, Dietary] results in increased expression of FABP3 protein]
|
CTD |
PMID:21135038 |
|
NCBI chr 5:147,936,027...147,942,870
Ensembl chr 5:147,936,119...147,942,881
|
|
| G
|
Gas6
|
growth arrest specific 6
|
multiple interactions
|
EXP
|
GAS6 protein promotes the reaction [Desoxycorticosterone results in increased expression of IL6 protein]; GAS6 protein promotes the reaction [Desoxycorticosterone results in increased expression of TNF protein]
|
CTD |
PMID:19564549 |
|
NCBI chr16:76,045,430...76,075,904
Ensembl chr16:82,747,345...82,778,088
|
|
| G
|
Gpx1
|
glutathione peroxidase 1
|
multiple interactions
|
EXP
|
[Desoxycorticosterone co-treated with Sodium Chloride] results in decreased expression of GPX1 protein; acetovanillone inhibits the reaction [[Desoxycorticosterone co-treated with Sodium Chloride] results in decreased expression of GPX1 protein]; atrasentan inhibits the reaction [[Desoxycorticosterone co-treated with Sodium Chloride] results in decreased expression of GPX1 protein]
|
CTD |
PMID:22431579 |
|
NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:117,905,280...117,906,581
|
|
| G
|
Havcr1
|
hepatitis A virus cellular receptor 1
|
multiple interactions
|
EXP
|
[Desoxycorticosterone co-treated with Sodium Chloride, Dietary] results in increased expression of HAVCR1 mRNA
|
CTD |
PMID:21135038 |
|
NCBI chr10:31,619,914...31,652,955
Ensembl chr10:31,619,897...31,653,268
|
|
| G
|
Il1b
|
interleukin 1 beta
|
multiple interactions
|
EXP
|
[Desoxycorticosterone co-treated with Sodium Chloride, Dietary] results in increased expression of IL1B mRNA
|
CTD |
PMID:21135038 |
|
NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
|
|
| G
|
Il6
|
interleukin 6
|
increases expression multiple interactions
|
EXP
|
Desoxycorticosterone results in increased expression of IL6 protein GAS6 protein promotes the reaction [Desoxycorticosterone results in increased expression of IL6 protein]
|
CTD |
PMID:19564549 |
|
NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
|
|
| G
|
Lcn2
|
lipocalin 2
|
multiple interactions
|
EXP
|
[Desoxycorticosterone co-treated with Sodium Chloride, Dietary] results in increased expression of LCN2 mRNA; Mineralocorticoid Receptor Antagonists inhibits the reaction [[Desoxycorticosterone co-treated with Sodium Chloride, Dietary] results in increased expression of LCN2 mRNA]
|
CTD |
PMID:21135038 |
|
NCBI chr 3:36,078,432...36,081,851
Ensembl chr 3:36,078,436...36,081,842
|
|
| G
|
Ncf1
|
neutrophil cytosolic factor 1
|
affects localization
|
EXP
|
Desoxycorticosterone affects the localization of NCF1 protein
|
CTD |
PMID:16271043 |
|
NCBI chr12:28,121,816...28,131,080
Ensembl chr12:28,121,366...28,131,079
|
|
| G
|
Nos3
|
nitric oxide synthase 3
|
decreases phosphorylation multiple interactions increases expression
|
EXP
|
Desoxycorticosterone results in decreased phosphorylation of NOS3 protein NOS3 protein inhibits the reaction [Desoxycorticosterone results in increased expression of VCAM1 protein] Desoxycorticosterone results in increased expression of NOS3 protein
|
CTD |
PMID:11834524 PMID:14993198 PMID:16271043 |
|
NCBI chr 4:11,686,088...11,706,604
Ensembl chr 4:11,686,268...11,706,664
|
|
| G
|
Nox1
|
NADPH oxidase 1
|
multiple interactions
|
EXP
|
[Desoxycorticosterone co-treated with Sodium Chloride] results in increased expression of NOX1 protein
|
CTD |
PMID:22431579 |
|
NCBI chr X:101,572,338...101,625,571
Ensembl chr X:101,572,340...101,595,520
|
|
| G
|
Nppa
|
natriuretic peptide A
|
increases expression
|
EXP
|
Desoxycorticosterone results in increased expression of NPPA protein
|
CTD |
PMID:2965178 |
|
NCBI chr 5:163,712,184...163,713,493
Ensembl chr 5:163,712,184...163,713,493
|
|
| G
|
Nr3c1
|
nuclear receptor subfamily 3, group C, member 1
|
increases phosphorylation multiple interactions decreases expression
|
ISO EXP
|
Desoxycorticosterone results in increased phosphorylation of NR3C1 protein Desoxycorticosterone promotes the reaction [NR3C1 protein binds to TAT promoter] Desoxycorticosterone results in decreased expression of NR3C1 mRNA Desoxycorticosterone binds to and results in increased activity of NR3C1 protein
|
CTD |
PMID:8969928 PMID:11956172 PMID:18483179 PMID:22465009 |
|
NCBI chr18:31,522,783...31,644,508
Ensembl chr18:31,522,783...31,643,843
|
|
| G
|
Nr3c2
|
nuclear receptor subfamily 3, group C, member 2
|
decreases expression
|
EXP
|
Desoxycorticosterone results in decreased expression of NR3C2 mRNA
|
CTD |
PMID:8969928 |
|
NCBI chr19:47,619,853...47,964,089
Ensembl chr19:47,619,853...47,964,078
|
|
| G
|
Pdgfa
|
platelet derived growth factor subunit A
|
multiple interactions
|
EXP
|
[PDGFA protein binds to PDGFB protein] which results in increased susceptibility to Desoxycorticosterone
|
CTD |
PMID:11751714 |
|
NCBI chr12:15,645,549...15,667,056
Ensembl chr12:20,754,208...20,780,322
|
|
| G
|
Pdgfb
|
platelet derived growth factor subunit B
|
multiple interactions
|
EXP
|
[PDGFA protein binds to PDGFB protein] which results in increased susceptibility to Desoxycorticosterone
|
CTD |
PMID:11751714 |
|
NCBI chr 7:113,419,882...113,438,343
Ensembl chr 7:113,420,710...113,438,343
|
|
| G
|
Pomc
|
proopiomelanocortin
|
increases abundance
|
ISO
|
POMC protein results in increased abundance of Desoxycorticosterone
|
CTD |
PMID:3015796 |
|
NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:32,659,346...32,665,173
|
|
| G
|
Ppara
|
peroxisome proliferator activated receptor alpha
|
multiple interactions
|
ISO
|
PPARA protein affects the susceptibility to [Sodium Chloride, Dietary co-treated with Desoxycorticosterone]
|
CTD |
PMID:16054168 |
|
NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:118,712,412...118,780,714
|
|
| G
|
Ppargc1a
|
PPARG coactivator 1 alpha
|
increases expression
|
ISO
|
Desoxycorticosterone results in increased expression of PPARGC1A mRNA
|
CTD |
PMID:23056435 |
|
NCBI chr14:63,073,505...63,729,215
Ensembl chr14:63,273,189...63,729,213
|
|
| G
|
Ptgs2
|
prostaglandin-endoperoxide synthase 2
|
increases expression
|
EXP
|
Desoxycorticosterone results in increased expression of PTGS2 protein
|
CTD |
PMID:15834289 PMID:16271043 |
|
NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320
|
|
| G
|
Rac1
|
Rac family small GTPase 1
|
multiple interactions
|
EXP
|
[Desoxycorticosterone co-treated with Sodium Chloride] results in increased expression of RAC1 protein
|
CTD |
PMID:22431579 |
|
NCBI chr12:16,150,411...16,170,864
Ensembl chr12:16,128,649...16,172,109
|
|
| G
|
Ren
|
renin
|
multiple interactions
|
EXP
|
[Desoxycorticosterone co-treated with Sodium Chloride] results in decreased expression of REN protein
|
CTD |
PMID:11039 |
|
NCBI chr13:47,348,312...47,359,539
Ensembl chr13:47,348,143...47,359,543
|
|
| G
|
Slc22a2
|
solute carrier family 22 member 2
|
multiple interactions
|
EXP
|
Desoxycorticosterone inhibits the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium]
|
CTD |
PMID:9830022 |
|
NCBI chr 1:50,668,817...50,711,019
Ensembl chr 1:50,668,817...50,711,019
|
|
| G
|
Slc22a3
|
solute carrier family 22 member 3
|
multiple interactions
|
EXP
|
Desoxycorticosterone inhibits the reaction [SLC22A3 protein results in increased uptake of Tetraethylammonium]
|
CTD |
PMID:9830022 |
|
NCBI chr 1:50,783,218...50,872,358
Ensembl chr 1:50,783,218...50,872,353
|
|
| G
|
Slco1a1
|
solute carrier organic anion transporter family, member 1a1
|
multiple interactions decreases activity
|
EXP
|
Desoxycorticosterone inhibits the reaction [SLCO1A1 protein results in increased uptake of estradiol-17 beta-glucuronide] Desoxycorticosterone results in decreased activity of SLCO1A1 protein
|
CTD |
PMID:11883641 |
|
NCBI chr 4:176,606,924...176,682,027
Ensembl chr 4:176,607,687...176,681,992
|
|
| G
|
Sod1
|
superoxide dismutase 1
|
decreases expression multiple interactions
|
EXP
|
Desoxycorticosterone results in decreased expression of SOD1 protein [Desoxycorticosterone co-treated with Sodium Chloride] results in decreased expression of SOD1 protein; acetovanillone inhibits the reaction [[Desoxycorticosterone co-treated with Sodium Chloride] results in decreased expression of SOD1 protein]; atrasentan inhibits the reaction [[Desoxycorticosterone co-treated with Sodium Chloride] results in decreased expression of SOD1 protein]; tempol inhibits the reaction [Desoxycorticosterone results in decreased expression of SOD1 protein]
|
CTD |
PMID:12646410 PMID:22431579 |
|
NCBI chr11:42,942,742...42,948,399
Ensembl chr11:42,942,678...42,948,399
|
|
| G
|
Sod2
|
superoxide dismutase 2
|
multiple interactions decreases expression
|
EXP
|
[Desoxycorticosterone co-treated with Sodium Chloride] results in decreased expression of SOD2 protein; acetovanillone inhibits the reaction [[Desoxycorticosterone co-treated with Sodium Chloride] results in decreased expression of SOD2 protein]; Atrasentan inhibits the reaction [[Desoxycorticosterone co-treated with Sodium Chloride] results in decreased expression of SOD2 protein]; SOD2 protein inhibits the reaction [Desoxycorticosterone results in increased expression of VCAM1 protein] Desoxycorticosterone results in decreased expression of SOD2 protein
|
CTD |
PMID:11834524 PMID:22431579 |
|
NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:50,043,325...50,050,168
|
|
| G
|
Spp1
|
secreted phosphoprotein 1
|
multiple interactions
|
EXP
|
[Desoxycorticosterone co-treated with Sodium Chloride, Dietary] results in increased expression of SPP1 mRNA; [Desoxycorticosterone co-treated with Sodium Chloride, Dietary] results in increased expression of SPP1 protein; Mineralocorticoid Receptor Antagonists inhibits the reaction [[Desoxycorticosterone co-treated with Sodium Chloride, Dietary] results in increased expression of SPP1 mRNA]
|
CTD |
PMID:21135038 |
|
NCBI chr14:5,613,569...5,620,695
Ensembl chr14:5,613,576...5,619,820
|
|
| G
|
Sult1a1
|
sulfotransferase family 1A member 1
|
multiple interactions
|
EXP
|
Desoxycorticosterone promotes the reaction [EP300 protein binds to SULT1A1 promoter]
|
CTD |
PMID:22465009 |
|
NCBI chr 1:190,702,592...190,706,112
Ensembl chr 1:190,702,592...190,706,131
|
|
| G
|
Tat
|
tyrosine aminotransferase
|
multiple interactions
|
EXP
|
Desoxycorticosterone promotes the reaction [EP300 protein binds to TAT promoter]; Desoxycorticosterone promotes the reaction [NR3C1 protein binds to TAT promoter]
|
CTD |
PMID:22465009 |
|
NCBI chr19:54,856,604...54,867,168
Ensembl chr19:54,856,563...54,867,482
|
|
| G
|
Tnc
|
tenascin C
|
multiple interactions
|
EXP
|
[Desoxycorticosterone co-treated with Sodium Chloride, Dietary] results in increased expression of TNC mRNA; Mineralocorticoid Receptor Antagonists inhibits the reaction [[Desoxycorticosterone co-treated with Sodium Chloride, Dietary] results in increased expression of TNC mRNA]; Spironolactone inhibits the reaction [[Desoxycorticosterone co-treated with Sodium Chloride, Dietary] results in increased expression of TNC mRNA]
|
CTD |
PMID:21135038 |
|
NCBI chr 5:82,391,340...82,476,197
Ensembl chr 5:82,391,340...82,476,131
|
|
| G
|
Tnf
|
tumor necrosis factor
|
multiple interactions increases expression
|
EXP
|
GAS6 protein promotes the reaction [Desoxycorticosterone results in increased expression of TNF protein]
|
CTD |
PMID:19564549 |
|
NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
|
|
| G
|
Tp53
|
tumor protein p53
|
multiple interactions
|
EXP
|
[Desoxycorticosterone co-treated with Sodium Chloride] results in increased expression of TP53 protein; acetovanillone inhibits the reaction [[Desoxycorticosterone co-treated with Sodium Chloride] results in increased expression of TP53 protein]; atrasentan inhibits the reaction [[Desoxycorticosterone co-treated with Sodium Chloride] results in increased expression of TP53 protein]
|
CTD |
PMID:22431579 |
|
NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299
|
|
| G
|
Vcam1
|
vascular cell adhesion molecule 1
|
multiple interactions increases expression
|
EXP
|
NOS3 protein inhibits the reaction [Desoxycorticosterone results in increased expression of VCAM1 protein]; SOD2 protein inhibits the reaction [Desoxycorticosterone results in increased expression of VCAM1 protein]
|
CTD |
PMID:11834524 |
|
NCBI chr 2:206,723,050...206,742,783
Ensembl chr 2:206,723,044...206,742,801
|
|
| G
|
Xdh
|
xanthine dehydrogenase
|
increases activity multiple interactions
|
EXP
|
Desoxycorticosterone results in increased activity of XDH protein Desoxycorticosterone promotes the reaction [XDH protein results in increased chemical synthesis of Reactive Oxygen Species]
|
CTD |
PMID:16271043 |
|
NCBI chr 6:27,282,319...27,344,022
Ensembl chr 6:27,282,057...27,344,350
|
|
|
|
| G
|
Adipoq
|
adiponectin, C1Q and collagen domain containing
|
multiple interactions
|
ISO
|
17-alpha-Hydroxyprogesterone inhibits the reaction [[Dexamethasone co-treated with Rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of and results in increased secretion of ADIPOQ protein]
|
CTD |
PMID:29782964 |
|
NCBI chr11:91,226,524...91,240,244
Ensembl chr11:91,226,180...91,240,169
|
|
| G
|
Ar
|
androgen receptor
|
increases activity multiple interactions
|
ISO
|
17-alpha-Hydroxyprogesterone results in increased activity of AR protein 17-alpha-Hydroxyprogesterone inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]
|
CTD |
PMID:21543282 PMID:33049310 |
|
NCBI chr X:67,135,317...67,304,476
Ensembl chr X:67,135,317...67,304,467
|
|
| G
|
Cyp11a1
|
cytochrome P450, family 11, subfamily a, polypeptide 1
|
multiple interactions
|
EXP
|
[Diethylstilbestrol results in decreased expression of CYP11A1 protein] which results in decreased abundance of 17-alpha-Hydroxyprogesterone
|
CTD |
PMID:23873838 |
|
NCBI chr 8:67,318,665...67,330,196
Ensembl chr 8:67,270,556...67,330,196
|
|
| G
|
Cyp17a1
|
cytochrome P450, family 17, subfamily a, polypeptide 1
|
affects abundance increases metabolic processing multiple interactions affects metabolic processing affects chemical synthesis
|
ISO
|
CYP17A1 protein affects the abundance of 17-alpha-Hydroxyprogesterone CYP17A1 protein results in increased metabolism of 17-alpha-Hydroxyprogesterone [[abiraterone results in decreased activity of CYP17A1 protein] which results in decreased hydroxylation of Progesterone] which results in increased chemical synthesis of 17-alpha-Hydroxyprogesterone; [CYP17A1 protein results in increased hydroxylation of Progesterone] which results in increased chemical synthesis of 17-alpha-Hydroxyprogesterone; [CYP17A1 protein results in increased metabolism of 17-alpha-Hydroxyprogesterone] which results in increased chemical synthesis of Androstenedione; Duloxetine Hydrochloride inhibits the reaction [[CYP17A1 protein results in increased hydroxylation of Progesterone] which results in increased chemical synthesis of 17-alpha-Hydroxyprogesterone]; Duloxetine Hydrochloride inhibits the reaction [[CYP17A1 protein results in increased metabolism of 17-alpha-Hydroxyprogesterone] which results in increased chemical synthesis of Androstenedione]; Duloxetine Hydrochloride inhibits the reaction [CYP17A1 protein results in increased metabolism of 17-alpha-Hydroxyprogesterone]; TNF protein inhibits the reaction [CYP17A1 protein affects the metabolism of 17-alpha-Hydroxyprogesterone]; Venlafaxine Hydrochloride inhibits the reaction [[CYP17A1 protein results in increased hydroxylation of Progesterone] which results in increased chemical synthesis of 17-alpha-Hydroxyprogesterone]; Venlafaxine Hydrochloride inhibits the reaction [[CYP17A1 protein results in increased metabolism of 17-alpha-Hydroxyprogesterone] which results in increased chemical synthesis of Androstenedione]; Venlafaxine Hydrochloride inhibits the reaction [CYP17A1 protein results in increased metabolism of 17-alpha-Hydroxyprogesterone] CYP17A1 protein affects the chemical synthesis of 17-alpha-Hydroxyprogesterone
|
CTD |
PMID:16030167 PMID:17194026 PMID:21427057 PMID:29100959 |
|
NCBI chr 1:255,476,861...255,484,547
Ensembl chr 1:255,476,861...255,482,974
|
|
| G
|
Esr1
|
estrogen receptor 1
|
multiple interactions
|
ISO
|
17-alpha-Hydroxyprogesterone binds to and results in increased activity of ESR1 protein
|
CTD |
PMID:33049310 |
|
NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:43,644,392...43,900,354
|
|
| G
|
Esr2
|
estrogen receptor 2
|
multiple interactions
|
ISO
|
17-alpha-Hydroxyprogesterone binds to and results in increased activity of ESR2 protein
|
CTD |
PMID:33049310 |
|
NCBI chr 6:100,589,553...100,645,240
Ensembl chr 6:100,545,206...100,644,709
|
|
| G
|
Fabp4
|
fatty acid binding protein 4
|
multiple interactions
|
ISO
|
[17-alpha-Hydroxyprogesterone co-treated with Rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of FABP4 protein
|
CTD |
PMID:29782964 |
|
NCBI chr 2:93,488,251...93,492,961
Ensembl chr 2:93,488,271...93,492,972
|
|
| G
|
Ins2
|
insulin 2
|
multiple interactions
|
ISO
|
17-alpha-Hydroxyprogesterone inhibits the reaction [[Dexamethasone co-treated with Rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of and results in increased secretion of ADIPOQ protein]; [17-alpha-Hydroxyprogesterone co-treated with Rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of FABP4 protein
|
CTD |
PMID:29782964 |
|
NCBI chr 1:207,272,738...207,421,998
Ensembl chr 1:207,272,742...207,273,805
|
|
| G
|
Nr1i2
|
nuclear receptor subfamily 1, group I, member 2
|
multiple interactions
|
ISO
|
17-alpha-Hydroxyprogesterone binds to and results in increased activity of NR1I2 protein
|
CTD |
PMID:33049310 |
|
NCBI chr11:75,965,717...76,006,733
Ensembl chr11:75,965,632...76,002,380
|
|
| G
|
Nr3c1
|
nuclear receptor subfamily 3, group C, member 1
|
multiple interactions
|
ISO
|
17-alpha-Hydroxyprogesterone analog binds to and results in increased activity of NR3C1 protein
|
CTD |
PMID:18060946 |
|
NCBI chr18:31,522,783...31,644,508
Ensembl chr18:31,522,783...31,643,843
|
|
| G
|
Pgr
|
progesterone receptor
|
multiple interactions
|
ISO
|
17-alpha-Hydroxyprogesterone analog binds to and results in increased activity of PGR protein
|
CTD |
PMID:18060946 |
|
NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:14,354,398...14,413,271
|
|
| G
|
Slc22a2
|
solute carrier family 22 member 2
|
multiple interactions
|
ISO
|
17-alpha-Hydroxyprogesterone inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium]
|
CTD |
PMID:21599003 |
|
NCBI chr 1:50,668,817...50,711,019
Ensembl chr 1:50,668,817...50,711,019
|
|
| G
|
Tnf
|
tumor necrosis factor
|
multiple interactions
|
ISO
|
TNF protein inhibits the reaction [CYP17A1 protein affects the metabolism of 17-alpha-Hydroxyprogesterone]
|
CTD |
PMID:16030167 |
|
NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
|
|
|
|
| G
|
Akr1b15
|
aldo-keto reductase family 1 member B15
|
multiple interactions
|
EXP
|
[AKR1B8 protein co-treated with NADP] affects the reduction of 21-dehydrocortisol
|
CTD |
PMID:18845131 |
|
NCBI chr 4:63,964,421...63,976,995
Ensembl chr 4:63,960,880...63,978,349
|
|
|
|
| G
|
Akr1c1
|
aldo-keto reductase family 1, member C1
|
affects reduction increases reduction
|
ISO
|
AKR1C1 protein affects the reduction of 5-alpha-Dihydroprogesterone AKR1C1 protein results in increased reduction of 5-alpha-Dihydroprogesterone
|
CTD |
PMID:11995921 PMID:12604236 |
|
NCBI chr17:70,720,397...70,747,285
Ensembl chr17:70,720,398...70,747,247
|
|
| G
|
Akr1c2
|
aldo-keto reductase family 1, member C2
|
affects reduction increases reduction
|
ISO
|
AKR1C2 protein affects the reduction of 5-alpha-Dihydroprogesterone AKR1C2 protein results in increased reduction of 5-alpha-Dihydroprogesterone
|
CTD |
PMID:11995921 PMID:12604236 |
|
NCBI chr17:70,669,684...70,717,935
Ensembl chr17:70,669,710...70,685,686
|
|
| G
|
Akr1c3
|
aldo-keto reductase family 1, member C3
|
increases chemical synthesis
|
ISO
|
AKR1C3 protein results in increased chemical synthesis of 5-alpha-Dihydroprogesterone
|
CTD |
PMID:25463305 |
|
NCBI chr17:71,020,884...71,037,779
Ensembl chr17:70,970,900...71,048,438
|
|
| G
|
Akr1d1
|
aldo-keto reductase family 1, member D1
|
increases chemical synthesis multiple interactions
|
ISO
|
AKR1D1 protein results in increased chemical synthesis of 5-alpha-Dihydroprogesterone AKR1D1 protein alternative form results in increased chemical synthesis of 5-alpha-Dihydroprogesterone [AKR1D1 protein alternative form results in increased reduction of Progesterone] which results in increased chemical synthesis of 5-alpha-Dihydroprogesterone
|
CTD |
PMID:18624455 PMID:30928400 |
|
NCBI chr 4:67,121,288...67,154,543
Ensembl chr 4:67,120,024...67,154,540
|
|
| G
|
Bcl2
|
BCL2, apoptosis regulator
|
multiple interactions increases expression
|
ISO
|
3-hydroxypregn-4-en-20-one inhibits the reaction [5-alpha-Dihydroprogesterone results in increased expression of BCL2 mRNA]
|
CTD |
PMID:19931389 |
|
NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900
|
|
| G
|
Cyp17a1
|
cytochrome P450, family 17, subfamily a, polypeptide 1
|
increases hydroxylation
|
ISO
|
CYP17A1 protein results in increased hydroxylation of 5-alpha-Dihydroprogesterone
|
CTD |
PMID:14522586 |
|
NCBI chr 1:255,476,861...255,484,547
Ensembl chr 1:255,476,861...255,482,974
|
|
| G
|
Egr2
|
early growth response 2
|
increases expression
|
EXP
|
5-alpha-Dihydroprogesterone results in increased expression of EGR2 mRNA; 5-alpha-Dihydroprogesterone results in increased expression of EGR2 protein
|
CTD |
PMID:17478888 |
|
NCBI chr20:21,050,149...21,055,201
Ensembl chr20:21,050,149...21,057,748
|
|
| G
|
Esr1
|
estrogen receptor 1
|
increases expression
|
ISO
|
5-alpha-Dihydroprogesterone results in increased expression of ESR1 mRNA
|
CTD |
PMID:17683929 |
|
NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:43,644,392...43,900,354
|
|
| G
|
Gsk3b
|
glycogen synthase kinase 3 beta
|
decreases expression
|
EXP
|
5-alpha-Dihydroprogesterone results in decreased expression of GSK3B protein
|
CTD |
PMID:17443805 |
|
NCBI chr11:76,004,502...76,154,665
Ensembl chr11:76,009,507...76,153,249
|
|
| G
|
Mapt
|
microtubule-associated protein tau
|
decreases expression increases phosphorylation
|
EXP
|
5-alpha-Dihydroprogesterone results in decreased expression of MAPT protein 5-alpha-Dihydroprogesterone results in increased phosphorylation of MAPT protein
|
CTD |
PMID:17443805 |
|
NCBI chr10:89,638,618...89,736,108
Ensembl chr10:89,638,599...89,736,108
|
|
| G
|
Nr1i2
|
nuclear receptor subfamily 1, group I, member 2
|
affects activity multiple interactions
|
ISO
|
5-alpha-Dihydroprogesterone affects the activity of NR1I2 protein 5-alpha-Dihydroprogesterone binds to and results in increased activity of NR1I2 protein NR1I2 protein affects the susceptibility to [5-alpha-Dihydroprogesterone co-treated with Methacholine Chloride]; NR1I2 protein affects the susceptibility to [5-alpha-Dihydroprogesterone co-treated with N-methylsulfonyl-6-(2-propargyloxyphenyl)hexanamide]
|
CTD |
PMID:15846226 PMID:16054614 PMID:17159084 PMID:21291553 |
|
NCBI chr11:75,965,717...76,006,733
Ensembl chr11:75,965,632...76,002,380
|
|
| G
|
Nr1i3
|
nuclear receptor subfamily 1, group I, member 3
|
increases activity
|
ISO
|
5-alpha-Dihydroprogesterone results in increased activity of NR1I3 protein
|
CTD |
PMID:28927721 |
|
NCBI chr13:83,632,940...83,638,193
Ensembl chr13:86,165,349...86,170,370
|
|
| G
|
Sox10
|
SRY-box transcription factor 10
|
increases expression
|
EXP
|
5-alpha-Dihydroprogesterone results in increased expression of SOX10 mRNA; 5-alpha-Dihydroprogesterone results in increased expression of SOX10 protein
|
CTD |
PMID:17478888 |
|
NCBI chr 7:112,605,721...112,615,097
Ensembl chr 7:112,605,721...112,615,990
|
|
| G
|
Srd5a1
|
steroid 5 alpha-reductase 1
|
multiple interactions increases chemical synthesis
|
ISO
|
[SRD5A1 protein results in increased metabolism of Progesterone] which results in increased chemical synthesis of 5-alpha-Dihydroprogesterone SRD5A1 protein results in increased chemical synthesis of 5-alpha-Dihydroprogesterone
|
CTD |
PMID:23183084 PMID:25463305 |
|
NCBI chr 1:35,514,914...35,548,898
Ensembl chr 1:35,514,846...35,548,903
|
|
|
|
| G
|
Abcb1a
|
ATP binding cassette subfamily B member 1A
|
multiple interactions increases expression increases secretion
|
ISO
|
ABCB1 gene polymorphism affects the susceptibility to [Methotrexate co-treated with Methylprednisolone]; ABCB1 protein results in increased susceptibility to [Methotrexate co-treated with Methylprednisolone]; Elacridar inhibits the reaction [ABCB1 protein results in increased secretion of Methylprednisolone]; valspodar inhibits the reaction [ABCB1 protein results in increased secretion of Methylprednisolone] Methylprednisolone results in increased expression of ABCB1 mRNA; Methylprednisolone results in increased expression of ABCB1 protein
|
CTD |
PMID:16932953 PMID:22079615 PMID:22464980 |
|
NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:26,312,409...26,397,135
|
|
| G
|
Abcg2
|
ATP binding cassette subfamily G member 2
|
multiple interactions
|
ISO
|
Methylprednisolone inhibits the reaction [ABCG2 protein affects the transport of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine]
|
CTD |
PMID:15365089 |
|
NCBI chr 4:89,006,056...89,132,915
Ensembl chr 4:89,005,969...89,132,493
|
|
| G
|
Ackr3
|
atypical chemokine receptor 3
|
decreases expression
|
ISO
|
Methylprednisolone results in decreased expression of ACKR3 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 9:90,799,682...90,811,246
Ensembl chr 9:98,246,605...98,260,214
|
|
| G
|
Adora2a
|
adenosine A2a receptor
|
decreases expression
|
ISO
|
Methylprednisolone results in decreased expression of ADORA2A mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr20:13,315,270...13,332,802
Ensembl chr20:13,315,270...13,332,802
|
|
| G
|
Akt1
|
AKT serine/threonine kinase 1
|
decreases phosphorylation multiple interactions
|
EXP
|
Methylprednisolone results in decreased phosphorylation of AKT1 protein naringin inhibits the reaction [Methylprednisolone results in decreased phosphorylation of AKT1 protein]
|
CTD |
PMID:15187100 PMID:30878453 |
|
NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610
|
|
| G
|
Alpl
|
alkaline phosphatase, biomineralization associated
|
multiple interactions increases secretion
|
EXP
|
Alendronate inhibits the reaction [Methylprednisolone results in increased secretion of ALPL protein]; Nebivolol promotes the reaction [Alendronate inhibits the reaction [Methylprednisolone results in increased secretion of ALPL protein]]
|
CTD |
PMID:30291735 |
|
NCBI chr 5:155,234,770...155,289,785
Ensembl chr 5:155,234,775...155,254,167
|
|
| G
|
Amigo2
|
adhesion molecule with Ig like domain 2
|
decreases expression
|
ISO
|
Methylprednisolone results in decreased expression of AMIGO2 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 7:130,270,639...130,273,735
Ensembl chr 7:130,270,554...130,282,218
|
|
| G
|
Antxr1
|
ANTXR cell adhesion molecule 1
|
increases expression
|
ISO
|
Methylprednisolone results in increased expression of ANTXR1 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 4:121,148,102...121,335,549
Ensembl chr 4:121,148,103...121,336,892
|
|
| G
|
Aox1
|
aldehyde oxidase 1
|
increases expression
|
ISO
|
Methylprednisolone results in increased expression of AOX1 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 9:67,073,831...67,152,980
Ensembl chr 9:67,073,821...67,152,980
|
|
| G
|
Ar
|
androgen receptor
|
multiple interactions
|
ISO
|
Methylprednisolone binds to and results in decreased activity of AR protein; Methylprednisolone binds to and results in increased activity of AR protein
|
CTD |
PMID:25752796 |
|
NCBI chr X:67,135,317...67,304,476
Ensembl chr X:67,135,317...67,304,467
|
|
| G
|
Asns
|
asparagine synthetase (glutamine-hydrolyzing)
|
decreases expression
|
ISO
|
Methylprednisolone results in decreased expression of ASNS mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 4:36,752,061...36,769,970
Ensembl chr 4:36,751,802...36,776,050
|
|
| G
|
Bax
|
BCL2 associated X, apoptosis regulator
|
multiple interactions
|
EXP
|
Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of BAX mRNA]; Methylprednisolone inhibits the reaction [Hydrogen Peroxide affects the expression of BAX mRNA]; Methylprednisolone inhibits the reaction [Hydrogen Peroxide affects the expression of BAX protein]
|
CTD |
PMID:17570061 PMID:26093215 |
|
NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429
|
|
| G
|
Bcl2
|
BCL2, apoptosis regulator
|
multiple interactions
|
EXP
|
Methylprednisolone inhibits the reaction [Hydrogen Peroxide affects the expression of BCL2 mRNA]; Methylprednisolone inhibits the reaction [Hydrogen Peroxide affects the expression of BCL2 protein]
|
CTD |
PMID:17570061 |
|
NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900
|
|
| G
|
Bcl2a1
|
BCL2-related protein A1
|
decreases expression
|
ISO
|
Methylprednisolone results in decreased expression of BCL2A1 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 8:98,596,806...98,604,890
Ensembl chr 8:98,596,650...98,604,890
|
|
| G
|
Bglap
|
bone gamma-carboxyglutamate protein
|
decreases secretion decreases expression multiple interactions
|
EXP
|
Methylprednisolone results in decreased secretion of BGLAP protein Methylprednisolone results in decreased expression of BGLAP mRNA; Methylprednisolone results in decreased expression of BGLAP protein [Nebivolol co-treated with Alendronate] inhibits the reaction [Methylprednisolone results in decreased secretion of BGLAP protein]; bisphenol A diglycidyl ether inhibits the reaction [Methylprednisolone results in decreased expression of BGLAP mRNA]; bisphenol A diglycidyl ether inhibits the reaction [Methylprednisolone results in decreased expression of BGLAP protein]; Methylprednisolone inhibits the reaction [bisphenol A diglycidyl ether results in increased expression of BGLAP mRNA]; Methylprednisolone inhibits the reaction [bisphenol A diglycidyl ether results in increased expression of BGLAP protein]
|
CTD |
PMID:30291735 PMID:37659742 |
|
NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:176,136,341...176,137,318
|
|
| G
|
Bst2
|
bone marrow stromal cell antigen 2
|
decreases expression
|
ISO
|
Methylprednisolone results in decreased expression of BST2 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr16:18,250,593...18,254,967
Ensembl chr16:18,251,847...18,254,967
|
|
| G
|
Capn2
|
calpain 2
|
multiple interactions
|
EXP
|
Methylprednisolone inhibits the reaction [Hydrogen Peroxide results in increased expression of CAPN2 protein]
|
CTD |
PMID:17570061 |
|
NCBI chr13:96,681,902...96,732,625
Ensembl chr13:96,681,848...96,732,625
|
|
| G
|
Casp3
|
caspase 3
|
multiple interactions
|
EXP
|
Methylprednisolone inhibits the reaction [Hydrogen Peroxide results in increased cleavage of and results in increased activity of CASP3 protein]
|
CTD |
PMID:17570061 |
|
NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
|
|
| G
|
Cat
|
catalase
|
multiple interactions decreases activity increases activity
|
EXP
|
[Methylprednisolone co-treated with Puromycin Aminonucleoside] results in increased activity of CAT protein; Alendronate inhibits the reaction [Methylprednisolone results in decreased activity of CAT protein]; Nebivolol promotes the reaction [Alendronate inhibits the reaction [Methylprednisolone results in decreased activity of CAT protein]] Methylprednisolone results in increased activity of CAT protein
|
CTD |
PMID:1942778 PMID:30291735 |
|
NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526
|
|
| G
|
Ccl20
|
C-C motif chemokine ligand 20
|
decreases expression
|
ISO
|
Methylprednisolone results in decreased expression of CCL20 mRNA; Methylprednisolone results in decreased expression of CCL20 protein
|
CTD |
PMID:19192274 |
|
NCBI chr 9:91,837,139...91,839,736
Ensembl chr 9:91,836,946...91,839,736
|
|
| G
|
Ccn1
|
cellular communication network factor 1
|
increases expression
|
ISO
|
Methylprednisolone results in increased expression of CCN1 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 2:237,222,730...237,225,689
Ensembl chr 2:237,222,432...237,225,883
|
|
| G
|
Ccn2
|
cellular communication network factor 2
|
increases expression
|
ISO
|
Methylprednisolone results in increased expression of CCN2 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 1:22,621,498...22,624,614
Ensembl chr 1:22,621,501...22,624,976
|
|
| G
|
Ccn5
|
cellular communication network factor 5
|
increases expression
|
ISO
|
Methylprednisolone results in increased expression of CCN5 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 3:172,910,670...172,922,064
Ensembl chr 3:172,910,681...172,922,062
|
|
| G
|
Clgn
|
calmegin
|
decreases expression
|
ISO
|
Methylprednisolone results in decreased expression of CLGN mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr19:41,601,568...41,633,207
Ensembl chr19:41,601,568...41,633,325
|
|
| G
|
Col1a1
|
collagen type I alpha 1 chain
|
multiple interactions increases expression
|
EXP ISO
|
Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA] Methylprednisolone results in increased expression of COL1A1 mRNA
|
CTD |
PMID:19192274 PMID:26093215 |
|
NCBI chr10:80,380,458...80,397,461
Ensembl chr10:80,380,453...80,397,460
|
|
| G
|
Col4a1
|
collagen type IV alpha 1 chain
|
multiple interactions
|
EXP
|
Methylprednisolone inhibits the reaction [Puromycin Aminonucleoside results in increased expression of COL4A1 mRNA]
|
CTD |
PMID:1762292 |
|
NCBI chr16:84,885,597...84,996,482
Ensembl chr16:84,885,597...84,996,482
|
|
| G
|
Ctsd
|
cathepsin D
|
multiple interactions
|
EXP
|
Methylprednisolone inhibits the reaction [Isoproterenol results in increased expression of CTSD mRNA]
|
CTD |
PMID:894732 |
|
NCBI chr 1:206,956,945...206,968,821
Ensembl chr 1:206,956,944...206,968,821
|
|
| G
|
Cxcl1
|
C-X-C motif chemokine ligand 1
|
decreases expression
|
ISO
|
Methylprednisolone results in decreased expression of CXCL1 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr14:17,477,542...17,479,321
Ensembl chr14:17,477,549...17,479,811
|
|
| G
|
Cxcl2
|
C-X-C motif chemokine ligand 2
|
decreases expression
|
ISO
|
Methylprednisolone results in decreased expression of CXCL2 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr14:17,465,210...17,467,255
Ensembl chr14:17,465,242...17,467,255
|
|
| G
|
Cxcl3
|
C-X-C motif chemokine ligand 3
|
decreases expression
|
ISO
|
Methylprednisolone results in decreased expression of CXCL1 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr14:17,571,900...17,573,624
Ensembl chr14:17,571,900...17,573,624
|
|
| G
|
Cxcr4
|
C-X-C motif chemokine receptor 4
|
decreases expression
|
ISO
|
Methylprednisolone results in decreased expression of CXCR4 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr13:42,630,383...42,634,288
Ensembl chr13:42,630,104...42,634,459
|
|
| G
|
Cyp3a2
|
cytochrome P450, family 3, subfamily a, polypeptide 2
|
decreases expression increases activity
|
ISO
|
Methylprednisolone results in decreased expression of CYP3A4 mRNA Methylprednisolone results in increased activity of CYP3A4 protein
|
CTD |
PMID:15964336 PMID:16837568 |
|
NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857
|
|
| G
|
Ddit4
|
DNA-damage-inducible transcript 4
|
increases expression multiple interactions
|
EXP
|
Methylprednisolone results in increased expression of DDIT4 protein Testosterone inhibits the reaction [Methylprednisolone results in increased expression of DDIT4 protein]
|
CTD |
PMID:21931329 |
|
NCBI chr20:28,434,938...28,437,037
Ensembl chr20:28,434,944...28,437,037
|
|
| G
|
Dio2
|
iodothyronine deiodinase 2
|
increases expression
|
ISO
|
Methylprednisolone results in increased expression of DIO2 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 6:109,665,523...109,679,809
Ensembl chr 6:115,396,308...115,410,594
|
|
| G
|
Dmd
|
dystrophin
|
multiple interactions
|
ISO
|
Methylprednisolone inhibits the reaction [DMD gene mutant form results in increased expression of RELA protein modified form]; Methylprednisolone inhibits the reaction [DMD gene mutant form results in increased expression of SIRT1 mRNA]
|
CTD |
PMID:26930420 |
|
NCBI chr X:47,272,324...49,504,219
Ensembl chr X:51,070,273...53,437,835
|
|
| G
|
Edn1
|
endothelin 1
|
multiple interactions
|
EXP
|
Methylprednisolone inhibits the reaction [Puromycin Aminonucleoside results in increased expression of EDN1 mRNA]
|
CTD |
PMID:7756592 |
|
NCBI chr17:22,660,799...22,666,687
Ensembl chr17:22,660,799...22,666,687
|
|
| G
|
Ednrb
|
endothelin receptor type B
|
multiple interactions
|
EXP
|
Methylprednisolone inhibits the reaction [Puromycin Aminonucleoside results in increased expression of EDNRB mRNA]
|
CTD |
PMID:7756592 |
|
NCBI chr15:87,055,490...87,086,765
Ensembl chr15:87,057,691...87,086,765
|
|
| G
|
Efemp1
|
EGF containing fibulin extracellular matrix protein 1
|
increases expression
|
ISO
|
Methylprednisolone results in increased expression of EFEMP1 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr14:106,811,769...106,890,961
Ensembl chr14:106,802,304...106,892,808
|
|
| G
|
Esr1
|
estrogen receptor 1
|
multiple interactions
|
ISO
|
Methylprednisolone binds to and results in increased activity of ESR1 protein
|
CTD |
PMID:25752796 |
|
NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:43,644,392...43,900,354
|
|
| G
|
F8
|
coagulation factor VIII
|
increases expression
|
ISO
|
Methylprednisolone results in increased expression of F8 protein
|
CTD |
PMID:20405515 |
|
NCBI chr18:140,848...172,330
Ensembl chr18:155,309...186,683
|
|
| G
|
Fabp4
|
fatty acid binding protein 4
|
increases expression multiple interactions
|
EXP
|
Methylprednisolone results in increased expression of FABP4 mRNA bisphenol A diglycidyl ether inhibits the reaction [Methylprednisolone results in increased expression of FABP4 mRNA]
|
CTD |
PMID:37659742 |
|
NCBI chr 2:93,488,251...93,492,961
Ensembl chr 2:93,488,271...93,492,972
|
|
| G
|
Fbln1
|
fibulin 1
|
increases expression
|
ISO
|
Methylprednisolone results in increased expression of FBLN1 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 7:118,190,347...118,269,965
Ensembl chr 7:118,190,478...118,269,965
|
|
| G
|
Fbxo32
|
F-box protein 32
|
increases expression multiple interactions
|
EXP
|
Methylprednisolone results in increased expression of FBXO32 protein Testosterone inhibits the reaction [Methylprednisolone results in increased expression of FBXO32 protein]
|
CTD |
PMID:21931329 |
|
NCBI chr 7:91,620,925...91,654,491
Ensembl chr 7:91,620,925...91,654,491
|
|
| G
|
Fcer2
|
Fc epsilon receptor II
|
multiple interactions
|
ISO
|
Methylprednisolone inhibits the reaction [IL4 protein promotes the reaction [STAT6 protein binds to FCER2 promoter]]; Methylprednisolone inhibits the reaction [IL4 protein results in increased expression of FCER2 mRNA]; Methylprednisolone inhibits the reaction [IL4 protein results in increased expression of FCER2 protein]
|
CTD |
PMID:11997017 |
|
NCBI chr12:6,540,697...6,552,364
Ensembl chr12:6,540,703...6,549,374
|
|
| G
|
Foxo1
|
forkhead box O1
|
increases expression multiple interactions
|
EXP
|
Methylprednisolone results in increased expression of FOXO1 protein echinacoside inhibits the reaction [Methylprednisolone results in increased expression of FOXO1 protein]; Testosterone inhibits the reaction [Methylprednisolone results in increased expression of FOXO1 protein]
|
CTD |
PMID:21931329 PMID:38336255 |
|
NCBI chr 2:138,462,974...138,541,420
Ensembl chr 2:138,462,697...138,541,419
|
|
| G
|
Gbp1
|
guanylate binding protein 1
|
decreases expression
|
ISO
|
Methylprednisolone results in decreased expression of GBP1 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 2:234,071,366...234,106,012
Ensembl chr 2:234,190,708...234,206,802 Ensembl chr 2:234,190,708...234,206,802
|
|
| G
|
Gfap
|
glial fibrillary acidic protein
|
decreases expression
|
ISO
|
Methylprednisolone results in decreased expression of GFAP protein
|
CTD |
PMID:18509235 |
|
NCBI chr10:88,352,987...88,361,661
Ensembl chr10:88,352,986...88,361,685
|
|
| G
|
Gip
|
gastric inhibitory polypeptide
|
increases secretion
|
EXP
|
Methylprednisolone results in increased secretion of GIP protein
|
CTD |
PMID:6753106 |
|
NCBI chr10:81,465,070...81,473,216
Ensembl chr10:81,465,062...81,473,216
|
|
| G
|
Gpm6b
|
glycoprotein m6b
|
increases expression
|
ISO
|
Methylprednisolone results in increased expression of GPM6B mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr X:31,689,485...31,836,199
Ensembl chr X:31,690,359...31,733,272
|
|
| G
|
Gpt
|
glutamic--pyruvic transaminase
|
multiple interactions
|
ISO
|
[Polymyxin B co-treated with Methylprednisolone] inhibits the reaction [Alpha-Amanitin results in increased expression of GPT protein]; Methylprednisolone inhibits the reaction [Alpha-Amanitin results in increased expression of GPT protein]
|
CTD |
PMID:30891624 |
|
NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:110,296,206...110,300,160
|
|
| G
|
Gpx1
|
glutathione peroxidase 1
|
multiple interactions increases activity
|
EXP
|
[Methylprednisolone co-treated with Puromycin Aminonucleoside] results in increased activity of GPX1 protein Methylprednisolone results in increased activity of GPX1 protein
|
CTD |
PMID:1942778 |
|
NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:117,905,280...117,906,581
|
|
| G
|
Gsdme
|
gasdermin E
|
decreases expression
|
ISO
|
Methylprednisolone results in decreased expression of GSDME mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 4:80,590,344...80,651,943
Ensembl chr 4:80,588,614...80,641,525
|
|
| G
|
Herc6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
decreases expression
|
ISO
|
Methylprednisolone results in decreased expression of HERC6 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 4:88,854,612...88,897,043
Ensembl chr 4:88,854,640...88,896,993
|
|
| G
|
Hilpda
|
hypoxia inducible lipid droplet-associated
|
decreases expression
|
ISO
|
Methylprednisolone results in decreased expression of HILPDA mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 4:57,871,088...57,874,048
Ensembl chr 4:58,836,463...58,839,423
|
|
| G
|
Hmox1
|
heme oxygenase 1
|
multiple interactions
|
EXP
|
Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of HMOX1 mRNA]
|
CTD |
PMID:26093215 |
|
NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818
|
|
| G
|
Hsd11b1
|
hydroxysteroid 11-beta dehydrogenase 1
|
decreases expression
|
ISO
|
Methylprednisolone results in decreased expression of HSD11B1 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr13:107,277,526...107,327,462
Ensembl chr13:107,257,239...107,327,432
|
|
| G
|
Htr3a
|
5-hydroxytryptamine receptor 3A
|
multiple interactions decreases activity
|
ISO
|
[Methylprednisolone co-treated with Metoclopramide] results in decreased activity of HTR3A protein; [Methylprednisolone co-treated with ramosetron] results in decreased activity of HTR3A protein Methylprednisolone results in decreased activity of HTR3A protein
|
CTD |
PMID:15329590 |
|
NCBI chr 8:58,138,514...58,150,960
Ensembl chr 8:58,138,226...58,150,884
|
|
| G
|
Id3
|
inhibitor of DNA binding 3
|
increases expression
|
ISO
|
Methylprednisolone results in increased expression of ID3 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 5:153,656,253...153,657,860
Ensembl chr 5:153,630,498...153,657,856
|
|
| G
|
Ifi27
|
interferon, alpha-inducible protein 27
|
decreases expression
|
ISO
|
Methylprednisolone results in decreased expression of IFI27 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 6:128,355,312...128,361,783
Ensembl chr 6:128,355,079...128,361,781
|
|
| G
|
Ifi35
|
interferon-induced protein 35
|
decreases expression
|
ISO
|
Methylprednisolone results in decreased expression of IFI35 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr10:86,881,270...86,889,523
Ensembl chr10:86,887,122...86,889,750
|
|
| G
|
Ifi44
|
interferon-induced protein 44
|
decreases expression
|
ISO
|
Methylprednisolone results in decreased expression of IFI44 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 2:243,286,050...243,303,869
Ensembl chr 2:243,286,052...243,306,877
|
|
| G
|
Ifi44l
|
interferon-induced protein 44-like
|
decreases expression
|
ISO
|
Methylprednisolone results in decreased expression of IFI44L mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 2:240,668,742...240,706,425
Ensembl chr 2:243,328,723...243,366,404
|
|
| G
|
Ifih1
|
interferon induced with helicase C domain 1
|
decreases expression
|
ISO
|
Methylprednisolone results in decreased expression of IFIH1 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 3:67,635,924...67,683,968
Ensembl chr 3:67,637,545...67,683,968
|
|
| G
|
Ifit3
|
interferon-induced protein with tetratricopeptide repeats 3
|
decreases expression
|
ISO
|
Methylprednisolone results in decreased expression of IFIT3 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 1:241,527,326...241,532,469
Ensembl chr 1:241,526,880...241,532,521
|
|
| G
|
Il10
|
interleukin 10
|
increases expression
|
ISO
|
Methylprednisolone results in increased expression of IL10 protein
|
CTD |
PMID:28557239 |
|
NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580
|
|
| G
|
Il1b
|
interleukin 1 beta
|
multiple interactions
|
EXP
|
Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of IL1B mRNA]
|
CTD |
PMID:26093215 |
|
NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
|
|
| G
|
Il1rn
|
interleukin 1 receptor antagonist
|
decreases expression
|
ISO
|
Methylprednisolone results in decreased expression of IL1RN mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 3:27,509,836...27,525,738
Ensembl chr 3:27,509,798...27,525,732
|
|
| G
|
Il23a
|
interleukin 23 subunit alpha
|
decreases expression
|
ISO
|
Methylprednisolone results in decreased expression of IL23A mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 7:1,306,320...1,308,434
Ensembl chr 7:1,306,320...1,308,434
|
|
| G
|
Il4
|
interleukin 4
|
multiple interactions decreases expression
|
ISO
|
Methylprednisolone inhibits the reaction [IL4 protein promotes the reaction [STAT6 protein binds to FCER2 promoter]]; Methylprednisolone inhibits the reaction [IL4 protein results in increased activity of and results in increased phosphorylation of STAT6 protein]; Methylprednisolone inhibits the reaction [IL4 protein results in increased expression of FCER2 mRNA]; Methylprednisolone inhibits the reaction [IL4 protein results in increased expression of FCER2 protein]; Methylprednisolone inhibits the reaction [IL4 protein results in increased expression of IL4R mRNA]; Methylprednisolone inhibits the reaction [IL4 protein results in increased expression of IL4R protein]; Methylprednisolone inhibits the reaction [IL4 protein results in increased phosphorylation of IL4R protein]; Methylprednisolone inhibits the reaction [IL4 protein results in increased phosphorylation of JAK1 protein] Methylprednisolone results in decreased expression of IL4 protein
|
CTD |
PMID:7988651 PMID:11997017 |
|
NCBI chr10:38,272,003...38,277,549
Ensembl chr10:38,272,003...38,277,549
|
|
| G
|
Il4r
|
interleukin 4 receptor
|
multiple interactions
|
ISO
|
Methylprednisolone inhibits the reaction [IL4 protein results in increased expression of IL4R mRNA]; Methylprednisolone inhibits the reaction [IL4 protein results in increased expression of IL4R protein]; Methylprednisolone inhibits the reaction [IL4 protein results in increased phosphorylation of IL4R protein]
|
CTD |
PMID:11997017 |
|
NCBI chr 1:189,545,739...189,570,639
Ensembl chr 1:189,544,988...189,570,636
|
|
| G
|
Il5
|
interleukin 5
|
decreases expression
|
ISO
|
Methylprednisolone results in decreased expression of IL5 protein
|
CTD |
PMID:7988651 |
|
NCBI chr10:38,375,132...38,378,003
Ensembl chr10:38,375,132...38,378,003
|
|
| G
|
Il6
|
interleukin 6
|
multiple interactions decreases expression
|
EXP ISO
|
Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of IL6 mRNA] Methylprednisolone results in decreased expression of IL6 mRNA; Methylprednisolone results in decreased expression of IL6 protein
|
CTD |
PMID:19192274 PMID:26093215 |
|
NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
|
|
| G
|
Ins1
|
insulin 1
|
multiple interactions
|
ISO
|
cobaltiprotoporphyrin inhibits the reaction [Methylprednisolone inhibits the reaction [Glucose results in increased secretion of INS1 protein]]; Methylprednisolone inhibits the reaction [Glucose results in increased secretion of INS1 protein]
|
CTD |
PMID:15919478 |
|
NCBI chr 1:261,186,119...261,186,686
Ensembl chr 1:261,186,119...261,186,682
|
|
| G
|
Irf7
|
interferon regulatory factor 7
|
decreases expression
|
ISO
|
Methylprednisolone results in decreased expression of IRF7 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 1:205,796,956...205,800,543
Ensembl chr 1:205,796,959...205,800,023
|
|
| G
|
Isg15
|
ISG15 ubiquitin-like modifier
|
decreases expression
|
ISO
|
Methylprednisolone results in decreased expression of ISG15 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 5:172,066,369...172,067,656
Ensembl chr 5:172,066,369...172,067,656
|
|
| G
|
Isg20
|
interferon stimulated exonuclease gene 20
|
decreases expression
|
ISO
|
Methylprednisolone results in decreased expression of ISG20 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 1:142,234,729...142,246,403
Ensembl chr 1:142,236,137...142,246,401
|
|
| G
|
Jak1
|
Janus kinase 1
|
multiple interactions
|
ISO
|
Methylprednisolone inhibits the reaction [IL4 protein results in increased phosphorylation of JAK1 protein]
|
CTD |
PMID:11997017 |
|
NCBI chr 5:115,780,248...115,888,841
Ensembl chr 5:120,896,046...120,996,758
|
|
| G
|
Lamb1
|
laminin subunit beta 1
|
multiple interactions
|
EXP
|
Methylprednisolone inhibits the reaction [Puromycin Aminonucleoside results in increased expression of LAMB1 mRNA]
|
CTD |
PMID:1762292 |
|
NCBI chr 6:47,835,492...47,902,585
Ensembl chr 6:53,563,073...53,630,760
|
|
| G
|
Lamb2
|
laminin subunit beta 2
|
multiple interactions
|
EXP
|
Methylprednisolone inhibits the reaction [Puromycin Aminonucleoside results in increased expression of LAMB2 mRNA]
|
CTD |
PMID:1762292 |
|
NCBI chr 8:109,178,367...109,190,552
Ensembl chr 8:118,056,935...118,069,090
|
|
| G
|
Lamb3
|
laminin subunit beta 3
|
decreases expression
|
ISO
|
Methylprednisolone results in decreased expression of LAMB3 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr13:107,362,514...107,404,081
Ensembl chr13:107,322,526...107,404,081
|
|
| G
|
Ly6e
|
lymphocyte antigen 6 family member E
|
decreases expression
|
ISO
|
Methylprednisolone results in decreased expression of LY6E mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 7:108,815,970...108,820,444
Ensembl chr 7:108,816,887...108,820,443
|
|
| G
|
Mapk1
|
mitogen activated protein kinase 1
|
multiple interactions decreases expression decreases phosphorylation
|
EXP
|
cobaltous chloride inhibits the reaction [Methylprednisolone results in decreased expression of MAPK1 protein modified form]; cobaltous chloride inhibits the reaction [Methylprednisolone results in decreased phosphorylation of MAPK1 protein]
|
CTD |
PMID:12904460 |
|
NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825
|
|
| G
|
Marcks
|
myristoylated alanine rich protein kinase C substrate
|
decreases expression
|
ISO
|
Methylprednisolone results in decreased expression of MARCKS mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr20:42,240,185...42,245,882
Ensembl chr20:42,240,185...42,245,882
|
|
| G
|
Mbp
|
myelin basic protein
|
decreases expression
|
ISO
|
Methylprednisolone results in decreased expression of MBP protein
|
CTD |
PMID:18509235 |
|
NCBI chr18:78,130,652...78,241,174
Ensembl chr18:78,130,325...78,241,174
|
|
| G
|
Met
|
MET proto-oncogene, receptor tyrosine kinase
|
decreases expression
|
ISO
|
Methylprednisolone results in decreased expression of MET mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 4:46,756,823...46,864,041
Ensembl chr 4:46,756,506...46,870,821
|
|
| G
|
Mmp10
|
matrix metallopeptidase 10
|
decreases expression
|
ISO
|
Methylprednisolone results in decreased expression of MMP10 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 8:12,974,707...12,982,613
Ensembl chr 8:12,974,707...12,982,613
|
|
| G
|
Mmp12
|
matrix metallopeptidase 12
|
decreases expression
|
ISO
|
Methylprednisolone results in decreased expression of MMP12 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 8:4,581,785...4,591,687
Ensembl chr 8:12,866,641...12,884,478
|
|
| G
|
Mpo
|
myeloperoxidase
|
multiple interactions decreases expression
|
EXP ISO
|
Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of MPO protein] [Polymyxin B co-treated with Methylprednisolone] inhibits the reaction [Alpha-Amanitin results in increased activity of MPO protein]; Methylprednisolone inhibits the reaction [Alpha-Amanitin results in increased activity of MPO protein] Methylprednisolone results in decreased expression of MPO protein
|
CTD |
PMID:26093215 PMID:28557239 PMID:30891624 |
|
NCBI chr10:72,594,883...72,608,862
Ensembl chr10:73,092,400...73,102,056
|
|
| G
|
Muc5ac
|
mucin 5AC, oligomeric mucus/gel-forming
|
multiple interactions
|
EXP
|
Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of MUC5AC mRNA]
|
CTD |
PMID:26093215 |
|
NCBI chr 1:196,864,336...196,896,475
Ensembl chr 1:206,293,869...206,326,006
|
|
| G
|
Mx1
|
MX dynamin like GTPase 1
|
decreases expression
|
ISO
|
Methylprednisolone results in decreased expression of MX1 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr11:50,269,056...50,294,699
Ensembl chr11:50,269,057...50,292,904
|
|
| G
|
Ndufa4l2
|
NDUFA4, mitochondrial complex associated like 2
|
decreases expression
|
ISO
|
Methylprednisolone results in decreased expression of NDUFA4L2 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 7:65,242,169...65,244,296
Ensembl chr 7:65,242,135...65,244,277
|
|
| G
|
Nfe2l2
|
NFE2 like bZIP transcription factor 2
|
multiple interactions
|
EXP
|
Methylprednisolone inhibits the reaction [Bleomycin results in decreased expression of NFE2L2 mRNA]
|
CTD |
PMID:26093215 |
|
NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090
|
|
| G
|
Nfkb1
|
nuclear factor kappa B subunit 1
|
multiple interactions
|
EXP
|
Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of NFKB1 mRNA]
|
CTD |
PMID:26093215 |
|
NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:226,689,745...226,783,088
|
|
| G
|
Nid2
|
nidogen 2
|
increases expression
|
ISO
|
Methylprednisolone results in increased expression of NID2 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr15:4,507,224...4,562,949
Ensembl chr15:4,506,756...4,562,949
|
|
| G
|
Nmb
|
neuromedin B
|
decreases expression
|
ISO
|
Methylprednisolone results in decreased expression of NMB mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 1:144,278,678...144,290,523
Ensembl chr 1:144,278,453...144,281,422
|
|
| G
|
Nos2
|
nitric oxide synthase 2
|
multiple interactions
|
EXP
|
Methylprednisolone inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]
|
CTD |
PMID:22422321 |
|
NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880
|
|
| G
|
Nr4a3
|
nuclear receptor subfamily 4, group A, member 3
|
decreases expression
|
ISO
|
Methylprednisolone results in decreased expression of NR4A3 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 5:67,157,141...67,198,287
Ensembl chr 5:67,157,375...67,198,285
|
|
| G
|
Oas1a
|
2'-5' oligoadenylate synthetase 1A
|
decreases expression
|
ISO
|
Methylprednisolone results in decreased expression of OAS1 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr12:41,330,423...41,341,130
Ensembl chr12:41,285,211...41,341,128
|
|
| G
|
Oas3
|
2'-5'-oligoadenylate synthetase 3
|
decreases expression
|
ISO
|
Methylprednisolone results in decreased expression of OAS3 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr12:35,779,028...35,802,781
Ensembl chr12:41,439,643...41,464,420
|
|
| G
|
Oasl
|
2'-5'-oligoadenylate synthetase-like
|
decreases expression
|
ISO
|
Methylprednisolone results in decreased expression of OASL mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr12:47,343,551...47,356,509
Ensembl chr12:47,343,551...47,356,483
|
|
| G
|
Phgdh
|
phosphoglycerate dehydrogenase
|
decreases expression
|
ISO
|
Methylprednisolone results in decreased expression of PHGDH mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 2:188,595,700...188,624,789
Ensembl chr 2:188,595,700...188,624,789
|
|
| G
|
Pla1a
|
phospholipase A1 member A
|
multiple interactions
|
ISO
|
Methylprednisolone inhibits the reaction [Lipopolysaccharides results in increased expression of PLA1A mRNA]
|
CTD |
PMID:20573295 |
|
NCBI chr11:62,320,112...62,357,779
Ensembl chr11:75,825,585...75,878,165
|
|
| G
|
Pla2g4a
|
phospholipase A2 group 4A
|
multiple interactions
|
ISO
|
Methylprednisolone inhibits the reaction [Lipopolysaccharides results in increased expression of PLA2G4A mRNA]
|
CTD |
PMID:20573295 |
|
NCBI chr13:64,427,921...64,572,352
Ensembl chr13:64,427,916...64,589,641
|
|
| G
|
Plpp3
|
phospholipid phosphatase 3
|
decreases expression
|
ISO
|
Methylprednisolone results in decreased expression of PLPP3 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 5:125,156,000...125,231,119
Ensembl chr 5:125,155,945...125,235,667
|
|
| G
|
Pparg
|
peroxisome proliferator-activated receptor gamma
|
multiple interactions increases expression
|
EXP
|
bisphenol A diglycidyl ether inhibits the reaction [Methylprednisolone results in increased expression of PPARG mRNA]; bisphenol A diglycidyl ether inhibits the reaction [Methylprednisolone results in increased expression of PPARG protein]; Methylprednisolone inhibits the reaction [bisphenol A diglycidyl ether results in decreased expression of PPARG mRNA]; Methylprednisolone inhibits the reaction [bisphenol A diglycidyl ether results in decreased expression of PPARG protein] Methylprednisolone results in increased expression of PPARG mRNA; Methylprednisolone results in increased expression of PPARG protein
|
CTD |
PMID:37659742 |
|
NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104
|
|
| G
|
Prelp
|
proline and arginine rich end leucine rich repeat protein
|
increases expression
|
ISO
|
Methylprednisolone results in increased expression of PRELP mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr13:45,368,407...45,391,480
Ensembl chr13:47,922,590...47,932,324
|
|
| G
|
Ptgs2
|
prostaglandin-endoperoxide synthase 2
|
decreases expression
|
ISO
|
Methylprednisolone results in decreased expression of PTGS2 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320
|
|
| G
|
Rela
|
RELA proto-oncogene, NF-kB subunit
|
multiple interactions
|
ISO
|
Methylprednisolone inhibits the reaction [DMD gene mutant form results in increased expression of RELA protein modified form]
|
CTD |
PMID:26930420 |
|
NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817
|
|
| G
|
Ren
|
renin
|
increases activity multiple interactions
|
EXP
|
Methylprednisolone results in increased activity of REN protein Sodium Chloride inhibits the reaction [Methylprednisolone results in increased activity of REN protein]
|
CTD |
PMID:235222 PMID:6277579 |
|
NCBI chr13:47,348,312...47,359,539
Ensembl chr13:47,348,143...47,359,543
|
|
| G
|
Rgs4
|
regulator of G-protein signaling 4
|
decreases expression
|
ISO
|
Methylprednisolone results in decreased expression of RGS4 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr13:84,469,593...84,475,884
Ensembl chr13:84,469,593...84,475,884
|
|
| G
|
Rig1
|
RNA sensor RIG-1
|
decreases expression
|
ISO
|
Methylprednisolone results in decreased expression of RIGI mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 5:55,321,351...55,369,947
Ensembl chr 5:60,117,398...60,165,995
|
|
| G
|
Ripk2
|
receptor-interacting serine-threonine kinase 2
|
decreases expression
|
ISO
|
Methylprednisolone results in decreased expression of RIPK2 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 5:29,630,806...29,662,804
Ensembl chr 5:34,428,573...34,459,663
|
|
| G
|
Rnf19b
|
ring finger protein 19B
|
decreases expression
|
ISO
|
Methylprednisolone results in decreased expression of RNF19B mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 5:141,406,085...141,431,376
Ensembl chr 5:146,690,577...146,714,394
|
|
| G
|
Rsad2
|
radical S-adenosyl methionine domain containing 2
|
decreases expression
|
ISO
|
Methylprednisolone results in decreased expression of RSAD2 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 6:48,774,985...48,788,245
Ensembl chr 6:48,774,985...48,788,320
|
|
| G
|
Runx2
|
RUNX family transcription factor 2
|
multiple interactions decreases expression
|
EXP
|
bisphenol A diglycidyl ether inhibits the reaction [Methylprednisolone results in decreased expression of RUNX2 mRNA]; bisphenol A diglycidyl ether inhibits the reaction [Methylprednisolone results in decreased expression of RUNX2 protein]; Methylprednisolone inhibits the reaction [bisphenol A diglycidyl ether results in increased expression of RUNX2 protein] Methylprednisolone results in decreased expression of RUNX2 mRNA; Methylprednisolone results in decreased expression of RUNX2 protein
|
CTD |
PMID:37659742 |
|
NCBI chr 9:23,661,278...23,990,248
Ensembl chr 9:23,664,952...23,990,027
|
|
| G
|
Sirt1
|
sirtuin 1
|
multiple interactions
|
ISO
|
Methylprednisolone inhibits the reaction [DMD gene mutant form results in increased expression of SIRT1 mRNA]
|
CTD |
PMID:26930420 |
|
NCBI chr20:25,305,953...25,328,000
Ensembl chr20:25,305,476...25,328,000
|
|
| G
|
Slc43a3
|
solute carrier family 43, member 3
|
decreases expression
|
ISO
|
Methylprednisolone results in decreased expression of SLC43A3 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 3:90,414,822...90,450,654
Ensembl chr 3:90,415,977...90,436,976
|
|
| G
|
Slc7a11
|
solute carrier family 7 member 11
|
decreases expression
|
ISO
|
Methylprednisolone results in decreased expression of SLC7A11 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 2:136,532,912...136,668,560
Ensembl chr 2:136,532,246...136,695,695
|
|
| G
|
Sms
|
spermine synthase
|
decreases expression
|
ISO
|
Methylprednisolone results in decreased expression of SMS mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr X:41,331,693...41,387,713
Ensembl chr X:41,331,799...41,387,712
|
|
| G
|
Sod2
|
superoxide dismutase 2
|
multiple interactions decreases expression increases activity
|
EXP ISO
|
[Methylprednisolone co-treated with Puromycin Aminonucleoside] results in increased activity of SOD2 protein Methylprednisolone results in decreased expression of SOD2 mRNA Methylprednisolone results in increased activity of SOD2 protein
|
CTD |
PMID:1942778 PMID:19192274 |
|
NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:50,043,325...50,050,168
|
|
| G
|
Stat1
|
signal transducer and activator of transcription 1
|
decreases expression
|
ISO
|
Methylprednisolone results in decreased expression of STAT1 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 9:56,911,522...56,951,926
Ensembl chr 9:56,911,523...57,077,346
|
|
| G
|
Stat4
|
signal transducer and activator of transcription 4
|
decreases expression
|
ISO
|
Methylprednisolone results in decreased expression of STAT4 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 9:49,472,660...49,588,540
Ensembl chr 9:56,911,523...57,077,346
|
|
| G
|
Stat6
|
signal transducer and activator of transcription 6
|
multiple interactions
|
ISO
|
Methylprednisolone inhibits the reaction [IL4 protein promotes the reaction [STAT6 protein binds to FCER2 promoter]]; Methylprednisolone inhibits the reaction [IL4 protein results in increased activity of and results in increased phosphorylation of STAT6 protein]
|
CTD |
PMID:11997017 |
|
NCBI chr 7:65,365,505...65,382,825
Ensembl chr 7:65,365,306...65,383,795
|
|
| G
|
Sts
|
steroid sulfatase
|
increases expression
|
ISO
|
Methylprednisolone results in increased expression of STS mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr X:46,102,524...46,110,868
Ensembl chr X:46,102,548...46,111,104
|
|
| G
|
Tgfb1
|
transforming growth factor, beta 1
|
multiple interactions
|
EXP
|
Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]
|
CTD |
PMID:26093215 |
|
NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899
|
|
| G
|
Thbs1
|
thrombospondin 1
|
increases expression
|
ISO
|
Methylprednisolone results in increased expression of THBS1 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 3:125,510,250...125,525,402
Ensembl chr 3:125,510,250...125,525,402
|
|
| G
|
Tlr2
|
toll-like receptor 2
|
decreases expression
|
ISO
|
Methylprednisolone results in decreased expression of TLR2 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 2:171,499,189...171,504,831
Ensembl chr 2:171,497,060...171,520,194
|
|
| G
|
Tnf
|
tumor necrosis factor
|
multiple interactions decreases expression
|
EXP ISO
|
Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of TNF mRNA]; Methylprednisolone inhibits the reaction [Puromycin Aminonucleoside results in increased expression of TNF mRNA] [Cyclophosphamide co-treated with Methylprednisolone] inhibits the reaction [Paraquat results in increased expression of TNF protein] Methylprednisolone results in decreased expression of TNF protein
|
CTD |
PMID:8384958 PMID:26093215 PMID:28557239 PMID:33737140 |
|
NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
|
|
| G
|
Tnfaip2
|
TNF alpha induced protein 2
|
decreases expression
|
ISO
|
Methylprednisolone results in decreased expression of TNFAIP2 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 6:130,476,832...130,489,914
Ensembl chr 6:136,298,082...136,311,106
|
|
| G
|
Trim63
|
tripartite motif containing 63
|
increases expression multiple interactions
|
EXP
|
Methylprednisolone results in increased expression of TRIM63 protein Testosterone inhibits the reaction [Methylprednisolone results in increased expression of TRIM63 protein]
|
CTD |
PMID:21931329 |
|
NCBI chr 5:151,817,209...151,831,026
Ensembl chr 5:151,817,225...151,831,058
|
|
| G
|
Txnip
|
thioredoxin interacting protein
|
increases expression
|
ISO
|
Methylprednisolone results in increased expression of TXNIP mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 2:186,781,933...186,785,736
Ensembl chr 2:186,781,163...186,785,731
|
|
| G
|
Vwf
|
von Willebrand factor
|
decreases expression increases expression
|
ISO
|
Methylprednisolone results in decreased expression of VWF protein Methylprednisolone results in increased expression of VWF protein
|
CTD |
PMID:7491699 PMID:20405515 |
|
NCBI chr 4:160,042,900...160,177,757
Ensembl chr 4:160,047,982...160,177,757
|
|
|
|
| G
|
Ccl2
|
C-C motif chemokine ligand 2
|
decreases expression
|
ISO
|
alclometasone dipropionate results in decreased expression of CCL2 protein
|
CTD |
PMID:20116850 |
|
NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875
|
|
| G
|
Ccl3
|
C-C motif chemokine ligand 3
|
increases expression
|
ISO
|
alclometasone dipropionate results in increased expression of CCL3 protein
|
CTD |
PMID:20116850 |
|
NCBI chr10:68,948,889...68,950,439
Ensembl chr10:68,948,889...68,950,439
|
|
| G
|
Ccl4
|
C-C motif chemokine ligand 4
|
increases expression
|
ISO
|
alclometasone dipropionate results in increased expression of CCL4 protein
|
CTD |
PMID:20116850 |
|
NCBI chr10:68,963,893...68,965,728
Ensembl chr10:68,950,289...68,965,722
|
|
| G
|
Csf2
|
colony stimulating factor 2
|
decreases expression
|
ISO
|
alclometasone dipropionate results in decreased expression of CSF2 protein
|
CTD |
PMID:11407316 |
|
NCBI chr10:38,887,692...38,889,673
Ensembl chr10:38,887,692...38,890,031
|
|
| G
|
Ifng
|
interferon gamma
|
decreases expression
|
ISO
|
alclometasone dipropionate results in decreased expression of IFNG protein
|
CTD |
PMID:11407316 |
|
NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216
|
|
| G
|
Il2
|
interleukin 2
|
decreases expression
|
ISO
|
alclometasone dipropionate results in decreased expression of IL2 protein
|
CTD |
PMID:11407316 |
|
NCBI chr 2:121,932,968...121,937,672
Ensembl chr 2:121,932,968...121,937,672
|
|
| G
|
Il3
|
interleukin 3
|
decreases expression
|
ISO
|
alclometasone dipropionate results in decreased expression of IL3 protein
|
CTD |
PMID:11407316 |
|
NCBI chr10:38,405,716...38,408,066
Ensembl chr10:38,906,460...38,908,810
|
|
| G
|
Il4
|
interleukin 4
|
decreases expression
|
ISO
|
alclometasone dipropionate results in decreased expression of IL4 protein
|
CTD |
PMID:11407316 |
|
NCBI chr10:38,272,003...38,277,549
Ensembl chr10:38,272,003...38,277,549
|
|
| G
|
Il5
|
interleukin 5
|
decreases expression
|
ISO
|
alclometasone dipropionate results in decreased expression of IL5 protein
|
CTD |
PMID:11407316 |
|
NCBI chr10:38,375,132...38,378,003
Ensembl chr10:38,375,132...38,378,003
|
|
| G
|
Vegfa
|
vascular endothelial growth factor A
|
decreases expression
|
ISO
|
alclometasone dipropionate results in decreased expression of VEGFA protein
|
CTD |
PMID:20116850 |
|
NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194
|
|
|
|
| G
|
Abcb1a
|
ATP binding cassette subfamily B member 1A
|
multiple interactions increases expression increases secretion
|
ISO
|
Beclomethasone inhibits the reaction [ABCB1 protein results in decreased susceptibility to Doxorubicin]; Beclomethasone inhibits the reaction [ABCB1 protein results in increased export of fluorexon]; Elacridar inhibits the reaction [ABCB1 protein results in increased secretion of Beclomethasone]; valspodar inhibits the reaction [ABCB1 protein results in increased secretion of Beclomethasone] Beclomethasone results in increased expression of ABCB1 mRNA; Beclomethasone results in increased expression of ABCB1 protein
|
CTD |
PMID:15370884 PMID:16442095 PMID:22464980 |
|
NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:26,312,409...26,397,135
|
|
| G
|
Abcb4
|
ATP binding cassette subfamily B member 4
|
increases expression
|
ISO
|
Beclomethasone results in increased expression of ABCB4 mRNA
|
CTD |
PMID:15370884 |
|
NCBI chr 4:26,106,895...26,164,440
|
|
| G
|
Abcc1
|
ATP binding cassette subfamily C member 1
|
increases expression
|
ISO
|
Beclomethasone results in increased expression of ABCC1 mRNA
|
CTD |
PMID:15370884 |
|
NCBI chr10:1,022,041...1,162,431
Ensembl chr10:1,038,947...1,162,404
|
|
| G
|
Abcg2
|
ATP binding cassette subfamily G member 2
|
multiple interactions increases activity
|
ISO
|
Beclomethasone inhibits the reaction [ABCG2 protein affects the transport of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine]; Beclomethasone inhibits the reaction [ABCG2 protein results in increased export of Mitoxantrone] Beclomethasone results in increased activity of ABCG2 protein
|
CTD |
PMID:15365089 PMID:16442095 |
|
NCBI chr 4:89,006,056...89,132,915
Ensembl chr 4:89,005,969...89,132,493
|
|
| G
|
Acp5
|
acid phosphatase 5, tartrate resistant
|
decreases activity
|
ISO
|
Beclomethasone results in decreased activity of ACP5 protein
|
CTD |
PMID:8429434 |
|
NCBI chr 8:28,939,984...28,946,639
Ensembl chr 8:28,939,985...28,943,929
|
|
| G
|
Adrb2
|
adrenoceptor beta 2
|
increases expression
|
ISO
|
Beclomethasone results in increased expression of ADRB2 mRNA
|
CTD |
PMID:9032216 PMID:15679717 |
|
NCBI chr18:57,912,760...57,914,802
Ensembl chr18:57,911,348...57,914,803
|
|
| G
|
Bdkrb1
|
bradykinin receptor B1
|
decreases expression
|
ISO
|
Beclomethasone results in decreased expression of BDKRB1 mRNA
|
CTD |
PMID:18039523 |
|
NCBI chr 6:130,275,631...130,284,968
Ensembl chr 6:130,275,478...130,280,973
|
|
| G
|
Bglap
|
bone gamma-carboxyglutamate protein
|
decreases expression
|
ISO
|
Beclomethasone results in decreased expression of BGLAP protein
|
CTD |
PMID:7746775 PMID:9232087 PMID:9544892 |
|
NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:176,136,341...176,137,318
|
|
| G
|
Casp9
|
caspase 9
|
increases activity
|
ISO
|
Beclomethasone results in increased activity of CASP9 protein
|
CTD |
PMID:11734450 |
|
Ensembl chr 5:159,391,188...159,409,648
|
|
| G
|
Cat
|
catalase
|
increases expression
|
ISO
|
Beclomethasone results in increased expression of CAT protein
|
CTD |
PMID:10445599 |
|
NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526
|
|
| G
|
Ccl11
|
C-C motif chemokine ligand 11
|
multiple interactions
|
ISO
|
Beclomethasone inhibits the reaction [IL13 protein results in increased expression of CCL11 protein]
|
CTD |
PMID:17988555 |
|
NCBI chr10:67,028,328...67,032,929
Ensembl chr10:67,525,862...67,530,575
|
|
| G
|
Ccl2
|
C-C motif chemokine ligand 2
|
decreases expression
|
ISO
|
Beclomethasone results in decreased expression of CCL2 protein
|
CTD |
PMID:20116850 |
|
NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875
|
|
| G
|
Ccl3
|
C-C motif chemokine ligand 3
|
increases expression
|
ISO
|
Beclomethasone results in increased expression of CCL3 protein
|
CTD |
PMID:20116850 |
|
NCBI chr10:68,948,889...68,950,439
Ensembl chr10:68,948,889...68,950,439
|
|
| G
|
Ccl4
|
C-C motif chemokine ligand 4
|
increases expression
|
ISO
|
Beclomethasone results in increased expression of CCL4 protein
|
CTD |
PMID:20116850 |
|
NCBI chr10:68,963,893...68,965,728
Ensembl chr10:68,950,289...68,965,722
|
|
| G
|
Ccl5
|
C-C motif chemokine ligand 5
|
multiple interactions decreases expression
|
ISO
|
[Beclomethasone co-treated with Albuterol] results in decreased secretion of CCL5 protein; [Beclomethasone co-treated with Formoterol Fumarate] results in decreased secretion of CCL5 protein; Beclomethasone inhibits the reaction [TNF protein results in increased secretion of CCL5 protein] Beclomethasone results in decreased expression of CCL5 mRNA; Beclomethasone results in decreased expression of CCL5 protein
|
CTD |
PMID:8534483 PMID:10903220 PMID:14643170 PMID:15679717 |
|
NCBI chr10:68,820,330...68,824,906
Ensembl chr10:68,738,651...68,824,884
|
|
| G
|
Cd44
|
CD44 molecule
|
multiple interactions
|
ISO
|
Albuterol promotes the reaction [Beclomethasone inhibits the reaction [FGF2 protein results in decreased expression of CD44 protein]]; Albuterol promotes the reaction [Beclomethasone inhibits the reaction [IL4 protein results in decreased expression of CD44 protein]]; Beclomethasone inhibits the reaction [FGF2 protein results in decreased expression of CD44 protein]; Beclomethasone inhibits the reaction [IL4 protein results in decreased expression of CD44 protein]; Formoterol Fumarate promotes the reaction [Beclomethasone inhibits the reaction [FGF2 protein results in decreased expression of CD44 protein]]; Formoterol Fumarate promotes the reaction [Beclomethasone inhibits the reaction [IL4 protein results in decreased expression of CD44 protein]]
|
CTD |
PMID:18076728 |
|
NCBI chr 3:109,610,824...109,699,776
Ensembl chr 3:109,612,054...109,699,424
|
|
| G
|
Csf2
|
colony stimulating factor 2
|
multiple interactions decreases secretion increases activity
|
ISO
|
[Beclomethasone co-treated with Albuterol] results in decreased secretion of CSF2 protein; [Beclomethasone co-treated with Formoterol Fumarate] results in decreased secretion of CSF2 protein; Beclomethasone inhibits the reaction [Antigens, Dermatophagoides results in increased expression of CSF2 mRNA]; Beclomethasone inhibits the reaction [Antigens, Dermatophagoides results in increased secretion of CSF2 protein]; Beclomethasone inhibits the reaction [IL1B protein results in increased secretion of CSF2 protein] Beclomethasone results in decreased secretion of CSF2 protein Beclomethasone results in increased activity of CSF2 protein
|
CTD |
PMID:7545059 PMID:10460758 PMID:10868704 PMID:11167953 PMID:11730731 PMID:15679717 More...
|
|
NCBI chr10:38,887,692...38,889,673
Ensembl chr10:38,887,692...38,890,031
|
|
| G
|
Cxcl10
|
C-X-C motif chemokine ligand 10
|
decreases secretion
|
ISO
|
Beclomethasone results in decreased secretion of CXCL10 protein
|
CTD |
PMID:17996064 |
|
NCBI chr14:15,989,066...15,991,263
Ensembl chr14:15,989,018...15,991,261
|
|
| G
|
Cyp2s1
|
cytochrome P450, family 2, subfamily s, polypeptide 1
|
decreases expression
|
ISO
|
Beclomethasone results in decreased expression of CYP2S1 mRNA
|
CTD |
PMID:22155357 |
|
NCBI chr 1:90,437,741...90,453,073
Ensembl chr 1:90,438,224...90,453,073
|
|
| G
|
Cyp3a9
|
cytochrome P450, family 3, subfamily a, polypeptide 9
|
multiple interactions increases expression
|
ISO
|
1-aminobenzotriazole inhibits the reaction [Beclomethasone results in increased expression of CYP3A5 mRNA]; Ketoconazole inhibits the reaction [Beclomethasone results in increased expression of CYP3A5 mRNA]; Mifepristone inhibits the reaction [Beclomethasone results in increased expression of CYP3A5 mRNA]; Paraoxon inhibits the reaction [Beclomethasone results in increased expression of CYP3A5 mRNA]; Physostigmine inhibits the reaction [Beclomethasone results in increased expression of CYP3A5 mRNA]
|
CTD |
PMID:12538830 PMID:23512537 PMID:24555085 |
|
NCBI chr12:21,919,955...21,960,160
Ensembl chr12:21,919,940...21,960,154
|
|
| G
|
Epx
|
eosinophil peroxidase
|
multiple interactions
|
EXP
|
Beclomethasone inhibits the reaction [sephadex results in increased expression of EPX protein]
|
CTD |
PMID:10850854 |
|
NCBI chr10:73,164,096...73,175,180
Ensembl chr10:73,164,096...73,175,180
|
|
| G
|
Fcer1g
|
Fc epsilon receptor Ig
|
decreases expression
|
EXP
|
Beclomethasone results in decreased expression of FCER1G protein
|
CTD |
PMID:1834581 |
|
NCBI chr13:86,181,908...86,186,766
Ensembl chr13:86,181,908...86,186,859
|
|
| G
|
Fgf2
|
fibroblast growth factor 2
|
multiple interactions decreases activity
|
ISO
|
[Beclomethasone co-treated with Albuterol] inhibits the reaction [FGF2 protein results in increased secretion of FN1 protein]; [Beclomethasone co-treated with Formoterol Fumarate] inhibits the reaction [FGF2 protein results in increased secretion of FN1 protein]; Albuterol promotes the reaction [Beclomethasone inhibits the reaction [FGF2 protein results in decreased expression of CD44 protein]]; Albuterol promotes the reaction [Beclomethasone inhibits the reaction [FGF2 protein results in decreased expression of THY1 protein]]; Albuterol promotes the reaction [Beclomethasone results in decreased activity of FGF2 protein]; Beclomethasone inhibits the reaction [FGF2 protein results in decreased expression of CD44 protein]; Beclomethasone inhibits the reaction [FGF2 protein results in decreased expression of THY1 protein]; Formoterol Fumarate promotes the reaction [Beclomethasone inhibits the reaction [FGF2 protein results in decreased expression of CD44 protein]]; Formoterol Fumarate promotes the reaction [Beclomethasone inhibits the reaction [FGF2 protein results in decreased expression of THY1 protein]]; Formoterol Fumarate promotes the reaction [Beclomethasone results in decreased activity of FGF2 protein]
|
CTD |
PMID:18076728 |
|
NCBI chr 2:122,164,454...122,218,796
Ensembl chr 2:122,164,454...122,224,493
|
|
| G
|
Fn1
|
fibronectin 1
|
multiple interactions
|
ISO
|
[Beclomethasone co-treated with Albuterol] inhibits the reaction [FGF2 protein results in increased secretion of FN1 protein]; [Beclomethasone co-treated with Formoterol Fumarate] inhibits the reaction [FGF2 protein results in increased secretion of FN1 protein]
|
CTD |
PMID:18076728 |
|
NCBI chr 9:80,645,507...80,714,200
Ensembl chr 9:80,645,507...80,714,137
|
|
| G
|
Fos
|
Fos proto-oncogene, AP-1 transcription factor subunit
|
decreases expression
|
ISO
|
Beclomethasone results in decreased expression of FOS protein
|
CTD |
PMID:9797757 |
|
NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598
|
|
| G
|
Ggt5
|
gamma-glutamyltransferase 5
|
increases activity increases expression multiple interactions
|
ISO
|
Beclomethasone results in increased activity of GGT5 protein Beclomethasone results in increased expression of GGT5 mRNA [Beclomethasone results in increased activity of GGT5 protein] which results in increased metabolism of Leukotriene C4
|
CTD |
PMID:11447392 |
|
NCBI chr20:13,042,694...13,070,960
Ensembl chr20:13,042,696...13,070,892
|
|
| G
|
Hsd11b2
|
hydroxysteroid 11-beta dehydrogenase 2
|
increases metabolic processing
|
ISO
|
HSD11B2 protein results in increased metabolism of Beclomethasone
|
CTD |
PMID:16549198 |
|
NCBI chr19:50,307,569...50,312,812
Ensembl chr19:50,307,569...50,312,812
|
|
| G
|
Icam1
|
intercellular adhesion molecule 1
|
multiple interactions
|
ISO
|
Beclomethasone inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]
|
CTD |
PMID:9150321 |
|
NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:27,829,161...27,841,617
|
|
| G
|
Il10
|
interleukin 10
|
decreases secretion
|
ISO
|
Beclomethasone results in decreased secretion of IL10 protein
|
CTD |
PMID:9819297 |
|
NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580
|
|
| G
|
Il13
|
interleukin 13
|
multiple interactions increases activity
|
ISO
|
Beclomethasone inhibits the reaction [IL13 protein results in increased expression of CCL11 protein]; Beclomethasone inhibits the reaction [IL13 protein results in increased expression of IL6 mRNA]; Beclomethasone inhibits the reaction [IL13 protein results in increased expression of IL6 protein] Beclomethasone results in increased activity of IL13 protein
|
CTD |
PMID:17988555 |
|
NCBI chr10:38,290,926...38,293,483
Ensembl chr10:38,290,926...38,293,483
|
|
| G
|
Il1b
|
interleukin 1 beta
|
multiple interactions decreases secretion decreases expression
|
ISO
|
Beclomethasone inhibits the reaction [IL1B protein results in increased expression of SELE mRNA]; Beclomethasone inhibits the reaction [IL1B protein results in increased secretion of CSF2 protein]; Beclomethasone inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein] Beclomethasone results in decreased secretion of IL1B protein Beclomethasone results in decreased expression of IL1B protein
|
CTD |
PMID:7545059 PMID:9176529 PMID:9371735 PMID:10460758 PMID:15337628 |
|
NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
|
|
| G
|
Il1rn
|
interleukin 1 receptor antagonist
|
decreases expression
|
ISO
|
Beclomethasone results in decreased expression of IL1RN protein
|
CTD |
PMID:11015126 |
|
NCBI chr 3:27,509,836...27,525,738
Ensembl chr 3:27,509,798...27,525,732
|
|
| G
|
Il2ra
|
interleukin 2 receptor subunit alpha
|
decreases expression
|
ISO
|
Beclomethasone results in decreased expression of IL2RA protein
|
CTD |
PMID:8111605 PMID:9314351 |
|
NCBI chr17:71,759,802...71,808,475
Ensembl chr17:71,759,802...71,808,507
|
|
| G
|
Il3
|
interleukin 3
|
multiple interactions
|
ISO
|
Beclomethasone inhibits the reaction [Antigens, Dermatophagoides results in increased expression of IL3 mRNA]; Beclomethasone inhibits the reaction [Antigens, Dermatophagoides results in increased secretion of IL3 protein]
|
CTD |
PMID:11167953 |
|
NCBI chr10:38,405,716...38,408,066
Ensembl chr10:38,906,460...38,908,810
|
|
| G
|
Il4
|
interleukin 4
|
multiple interactions decreases expression
|
ISO
|
Albuterol promotes the reaction [Beclomethasone inhibits the reaction [IL4 protein results in decreased expression of CD44 protein]]; Beclomethasone inhibits the reaction [IL4 protein results in decreased expression of CD44 protein]; Formoterol Fumarate promotes the reaction [Beclomethasone inhibits the reaction [IL4 protein results in decreased expression of CD44 protein]] Beclomethasone results in decreased expression of IL4 protein
|
CTD |
PMID:7988651 PMID:18076728 |
|
NCBI chr10:38,272,003...38,277,549
Ensembl chr10:38,272,003...38,277,549
|
|
| G
|
Il5
|
interleukin 5
|
multiple interactions decreases expression
|
ISO
|
Beclomethasone inhibits the reaction [Antigens, Dermatophagoides results in increased expression of IL5 mRNA]; Beclomethasone inhibits the reaction [Antigens, Dermatophagoides results in increased secretion of IL5 protein] Beclomethasone results in decreased expression of IL5 protein
|
CTD |
PMID:7988651 PMID:10813552 PMID:11167953 |
|
NCBI chr10:38,375,132...38,378,003
Ensembl chr10:38,375,132...38,378,003
|
|
| G
|
Il6
|
interleukin 6
|
multiple interactions
|
ISO
|
Beclomethasone inhibits the reaction [IL13 protein results in increased expression of IL6 mRNA]; Beclomethasone inhibits the reaction [IL13 protein results in increased expression of IL6 protein]
|
CTD |
PMID:17988555 |
|
NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
|
|
| G
|
Klk1c10
|
kallikrein 1-related peptidase C10
|
increases expression
|
ISO
|
Beclomethasone results in increased expression of KLK3 mRNA
|
CTD |
PMID:9815800 |
|
NCBI chr 1:94,402,993...94,407,052
Ensembl chr 1:103,539,527...103,543,586
|
|
| G
|
Ltf
|
lactotransferrin
|
multiple interactions decreases secretion
|
ISO
|
Beclomethasone inhibits the reaction [methylcholine results in increased secretion of LTF protein] Beclomethasone results in decreased secretion of LTF protein
|
CTD |
PMID:11112886 |
|
NCBI chr 8:110,999,948...111,022,795
Ensembl chr 8:119,878,344...119,901,189
|
|
| G
|
Mefv
|
MEFV innate immunity regulator, pyrin
|
increases response to substance
|
ISO
|
MEFV mutant form results in increased susceptibility to Beclomethasone
|
CTD |
PMID:20828792 |
|
NCBI chr10:11,786,948...11,796,977
Ensembl chr10:12,293,782...12,303,333
|
|
| G
|
Mmp2
|
matrix metallopeptidase 2
|
multiple interactions
|
ISO
|
Beclomethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP2 protein]
|
CTD |
PMID:10455257 |
|
NCBI chr19:30,327,643...30,355,856
Ensembl chr19:30,327,643...30,355,856
|
|
| G
|
Mmp9
|
matrix metallopeptidase 9
|
multiple interactions decreases expression
|
ISO
|
Beclomethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein] Beclomethasone results in decreased expression of MMP9 protein
|
CTD |
PMID:10452757 PMID:10455257 |
|
NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442
|
|
| G
|
Nos2
|
nitric oxide synthase 2
|
decreases expression
|
ISO
|
Beclomethasone results in decreased expression of NOS2 protein
|
CTD |
PMID:12668791 |
|
NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880
|
|
| G
|
Nr1i2
|
nuclear receptor subfamily 1, group I, member 2
|
increases activity
|
ISO
|
Beclomethasone results in increased activity of NR1I2 protein
|
CTD |
PMID:21068194 |
|
NCBI chr11:75,965,717...76,006,733
Ensembl chr11:75,965,632...76,002,380
|
|
| G
|
Nr3c1
|
nuclear receptor subfamily 3, group C, member 1
|
affects localization increases expression affects binding multiple interactions increases activity
|
ISO EXP
|
Beclomethasone affects the localization of NR3C1 protein Beclomethasone results in increased expression of NR3C1 mRNA Beclomethasone binds to NR3C1 protein [Beclomethasone co-treated with Albuterol] affects the localization of NR3C1 protein; [Beclomethasone co-treated with Formoterol Fumarate] affects the localization of NR3C1 protein; Beclomethasone affects the localization of and results in increased activity of NR3C1 protein; Beclomethasone binds to and results in increased activity of NR3C1 protein Beclomethasone results in increased activity of NR3C1 protein
|
CTD |
PMID:16814 PMID:2207292 PMID:15362971 PMID:15679717 PMID:15860753 PMID:15862954 PMID:16507850 PMID:21543282 PMID:24555085 More...
|
|
NCBI chr18:31,522,783...31,644,508
Ensembl chr18:31,522,783...31,643,843
|
|
| G
|
Nr3c2
|
nuclear receptor subfamily 3, group C, member 2
|
increases activity
|
ISO
|
Beclomethasone results in increased activity of NR3C2 protein
|
CTD |
PMID:15362971 |
|
NCBI chr19:47,619,853...47,964,089
Ensembl chr19:47,619,853...47,964,078
|
|
| G
|
Pla1a
|
phospholipase A1 member A
|
multiple interactions
|
ISO
|
Beclomethasone inhibits the reaction [Lipopolysaccharides results in increased expression of PLA1A mRNA]
|
CTD |
PMID:20573295 |
|
NCBI chr11:62,320,112...62,357,779
Ensembl chr11:75,825,585...75,878,165
|
|
| G
|
Pla2g4a
|
phospholipase A2 group 4A
|
decreases activity multiple interactions
|
ISO
|
Beclomethasone results in decreased activity of PLA2G4A protein Beclomethasone inhibits the reaction [Lipopolysaccharides results in increased expression of PLA2G4A mRNA]
|
CTD |
PMID:15337628 PMID:20573295 |
|
NCBI chr13:64,427,921...64,572,352
Ensembl chr13:64,427,916...64,589,641
|
|
| G
|
Ppp1r14a
|
protein phosphatase 1, regulatory (inhibitor) subunit 14A
|
multiple interactions
|
EXP
|
Beclomethasone inhibits the reaction [Acetylcholine results in increased phosphorylation of PPP1R14A protein]
|
CTD |
PMID:18577381 |
|
NCBI chr 1:93,708,269...93,718,218
Ensembl chr 1:93,708,218...93,719,147
|
|
| G
|
Rhoa
|
ras homolog family member A
|
multiple interactions
|
EXP
|
Beclomethasone inhibits the reaction [[[Antigens, Bacterial co-treated with Allergens] results in increased expression of and results in increased activity of RHOA protein] which results in increased susceptibility to Acetylcholine]; Beclomethasone inhibits the reaction [[Antigens, Bacterial co-treated with Allergens] results in increased expression of and results in increased activity of RHOA protein]; Beclomethasone inhibits the reaction [[Antigens, Bacterial co-treated with Allergens] results in increased expression of RHOA mRNA]
|
CTD |
PMID:18391481 |
|
NCBI chr 8:117,870,548...117,904,303
Ensembl chr 8:117,870,270...117,904,302
|
|
| G
|
Rnase2
|
ribonuclease A family member 2
|
decreases expression
|
ISO
|
Beclomethasone results in decreased expression of RNASE2 protein
|
CTD |
PMID:12166584 |
|
NCBI chr15:24,449,618...24,450,427
Ensembl chr15:26,923,134...26,923,955
|
|
| G
|
Rnase3
|
ribonuclease A family member 3
|
multiple interactions decreases expression
|
ISO
|
[Salmeterol Xinafoate co-treated with Beclomethasone] affects the reaction [Allergens results in increased expression of RNASE3 protein]; Beclomethasone affects the reaction [Allergens results in increased expression of RNASE3 protein] Beclomethasone results in decreased expression of RNASE3 protein
|
CTD |
PMID:1443864 PMID:10513351 PMID:10573242 PMID:12166584 PMID:12587966 PMID:15144908 More...
|
|
NCBI chr15:24,511,894...24,512,764
Ensembl chr15:26,985,271...26,986,400
|
|
| G
|
Sele
|
selectin E
|
multiple interactions
|
ISO
|
Beclomethasone inhibits the reaction [IL1B protein results in increased expression of SELE mRNA]
|
CTD |
PMID:9371735 |
|
NCBI chr13:78,935,997...78,945,905
Ensembl chr13:78,936,036...78,945,903
|
|
| G
|
Slc22a2
|
solute carrier family 22 member 2
|
multiple interactions
|
ISO
|
Beclomethasone inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium]
|
CTD |
PMID:21599003 |
|
NCBI chr 1:50,668,817...50,711,019
Ensembl chr 1:50,668,817...50,711,019
|
|
| G
|
Thy1
|
Thy-1 cell surface antigen
|
multiple interactions
|
ISO
|
Albuterol promotes the reaction [Beclomethasone inhibits the reaction [FGF2 protein results in decreased expression of THY1 protein]]; Beclomethasone inhibits the reaction [FGF2 protein results in decreased expression of THY1 protein]; Formoterol Fumarate promotes the reaction [Beclomethasone inhibits the reaction [FGF2 protein results in decreased expression of THY1 protein]]
|
CTD |
PMID:18076728 |
|
NCBI chr 8:53,286,396...53,291,541
Ensembl chr 8:53,286,148...53,291,540
|
|
| G
|
Timp1
|
TIMP metallopeptidase inhibitor 1
|
increases expression
|
ISO
|
Beclomethasone results in increased expression of TIMP1 protein
|
CTD |
PMID:10452757 |
|
NCBI chr X:3,766,509...3,772,578
Ensembl chr X:3,766,510...3,771,135
|
|
| G
|
Tnf
|
tumor necrosis factor
|
multiple interactions decreases secretion
|
ISO
|
Beclomethasone inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; Beclomethasone inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]; Beclomethasone inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]; Beclomethasone inhibits the reaction [TNF protein results in increased secretion of CCL5 protein]; Beclomethasone inhibits the reaction [TNF protein results in increased secretion of CXCL8 protein] Beclomethasone results in decreased secretion of TNF protein
|
CTD |
PMID:8937731 PMID:9150321 PMID:9819297 PMID:10100995 PMID:10903220 PMID:14643170 More...
|
|
NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
|
|
| G
|
Vcam1
|
vascular cell adhesion molecule 1
|
multiple interactions
|
ISO
|
Beclomethasone inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]
|
CTD |
PMID:10100995 |
|
NCBI chr 2:206,723,050...206,742,783
Ensembl chr 2:206,723,044...206,742,801
|
|
| G
|
Vegfa
|
vascular endothelial growth factor A
|
decreases expression
|
ISO
|
Beclomethasone results in decreased expression of VEGFA protein
|
CTD |
PMID:20116850 |
|
NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194
|
|
|
|
| G
|
Adipoq
|
adiponectin, C1Q and collagen domain containing
|
multiple interactions
|
ISO
|
Cyproterone Acetate inhibits the reaction [[Dexamethasone co-treated with Rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of and results in increased secretion of ADIPOQ protein]
|
CTD |
PMID:29782964 |
|
NCBI chr11:91,226,524...91,240,244
Ensembl chr11:91,226,180...91,240,169
|
|
| G
|
Apoa1
|
apolipoprotein A1
|
affects expression
|
ISO
|
Cyproterone Acetate affects the expression of APOA1 protein
|
CTD |
PMID:16323982 |
|
NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:55,423,825...55,425,729
|
|
| G
|
Apoa2
|
apolipoprotein A2
|
affects expression
|
ISO
|
Cyproterone Acetate affects the expression of APOA2 protein
|
CTD |
PMID:16323982 |
|
NCBI chr13:86,176,767...86,178,819
Ensembl chr13:86,174,741...86,179,410
|
|
| G
|
Ar
|
androgen receptor
|
multiple interactions increases response to substance affects localization decreases activity affects binding increases expression decreases expression
|
ISO EXP
|
[AR protein mutant form results in increased susceptibility to Cyproterone Acetate] which results in increased activity of AR protein mutant form; [Cyproterone Acetate binds to and affects the folding of AR protein] affects the reaction [AR protein modified form binds to NFKBIB protein modified form]; [Cyproterone Acetate binds to and affects the folding of AR protein] affects the reaction [AR protein modified form binds to NR0B1 protein modified form]; [Cyproterone Acetate binds to and affects the folding of AR protein] inhibits the reaction [AR protein modified form binds to HELZ2 protein modified form]; [Cyproterone Acetate binds to and affects the folding of AR protein] inhibits the reaction [AR protein modified form binds to MEN1 protein modified form]; [Cyproterone Acetate binds to and affects the folding of AR protein] inhibits the reaction [AR protein modified form binds to NCOR1 protein modified form]; [Cyproterone Acetate binds to and affects the folding of AR protein] inhibits the reaction [AR protein modified form binds to NRIP1 protein modified form]; [Cyproterone Acetate binds to and affects the folding of AR protein] inhibits the reaction [AR protein modified form binds to PELP1 protein modified form]; [Cyproterone Acetate binds to and affects the folding of AR protein] inhibits the reaction [AR protein modified form binds to PGR protein modified form]; [Cyproterone Acetate binds to and affects the folding of AR protein] inhibits the reaction [AR protein modified form binds to PPRC1 protein modified form]; [Cyproterone Acetate binds to and affects the folding of AR protein] inhibits the reaction [AR protein modified form binds to TGFB1I1 protein modified form]; [Cyproterone Acetate binds to and affects the folding of AR protein] inhibits the reaction [AR protein modified form binds to TRERF1 protein modified form]; [Cyproterone Acetate binds to and affects the folding of AR protein] inhibits the reaction [AR protein modified form binds to UBE3A protein modified form]; [Cyproterone Acetate binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to AR protein modified form]; [Cyproterone Acetate binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to BLOC1S1 protein modified form]; [Cyproterone Acetate binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to BRD8 protein modified form]; [Cyproterone Acetate binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to CHD9 protein modified form]; [Cyproterone Acetate binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to CNOT1 protein modified form]; [Cyproterone Acetate binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to CREBBP protein modified form]; [Cyproterone Acetate binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to DHX30 protein modified form]; [Cyproterone Acetate binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to EP300 protein modified form]; [Cyproterone Acetate binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to GNAQ protein modified form]; [Cyproterone Acetate binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to ITGB3BP protein modified form]; [Cyproterone Acetate binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to KIF11 protein modified form]; [Cyproterone Acetate binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to MED1 protein modified form]; [Cyproterone Acetate binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to MTA1 protein modified form]; [Cyproterone Acetate binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to NCOA2 protein modified form]; [Cyproterone Acetate binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to NCOA3 protein modified form]; [Cyproterone Acetate binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to NR0B2 protein modified form]; [Cyproterone Acetate binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to NRBF2 protein modified form]; [Cyproterone Acetate binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to PNRC2 protein modified form]; [Cyproterone Acetate binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to PRAME protein modified form]; [Cyproterone Acetate binds to AR protein] promotes the reaction [CREBBP protein binds to KLK3 enhancer]; [Cyproterone Acetate binds to AR protein] promotes the reaction [CREBBP protein binds to KLK3 promoter]; [Cyproterone Acetate binds to AR protein] promotes the reaction [NCOA2 protein binds to KLK3 enhancer]; [Cyproterone Acetate binds to AR protein] promotes the reaction [NCOA2 protein binds to KLK3 promoter]; [Cyproterone Acetate binds to AR protein] promotes the reaction [NCOR1 protein binds to KLK3 promoter]; Cyproterone Acetate binds to and affects the folding of AR protein; Cyproterone Acetate binds to and results in decreased activity of AR protein; Cyproterone Acetate binds to and results in increased activity of AR protein; Cyproterone Acetate inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; Cyproterone Acetate inhibits the reaction [[Dihydrotestosterone binds to and results in increased activity of AR protein] which results in increased expression of KLK3 protein]; Cyproterone Acetate inhibits the reaction [[Metribolone binds to and results in increased activity of AR protein] which results in increased expression of KLK3 protein]; Cyproterone Acetate inhibits the reaction [Cadmium Chloride results in decreased expression of AR protein]; Cyproterone Acetate inhibits the reaction [Dihydrotestosterone binds to and results in increased activity of AR protein]; Cyproterone Acetate inhibits the reaction [Dihydrotestosterone results in increased activity of AR protein]; Cyproterone Acetate inhibits the reaction [Metribolone results in increased activity of AR protein]; Cyproterone Acetate promotes the reaction [Metribolone results in increased expression of AR mRNA]; NCOA1 protein results in increased activity of [Cyproterone Acetate binds to AR protein]; PA2G4 protein inhibits the reaction [Cyproterone Acetate promotes the reaction [Metribolone results in increased expression of AR mRNA]]; PA2G4 protein inhibits the reaction [Cyproterone Acetate results in increased expression of AR mRNA] Cyproterone Acetate affects the localization of AR protein Cyproterone Acetate results in decreased activity of AR protein [Cyproterone Acetate binds to AR protein] which binds to KLK3 enhancer; [Cyproterone Acetate binds to AR protein] which binds to KLK3 promoter; Cyproterone Acetate binds to AR protein Cyproterone Acetate results in decreased expression of AR mRNA
|
CTD |
PMID:10053169 PMID:11751618 PMID:14565775 PMID:14751673 PMID:15084347 PMID:15110108 PMID:15308689 PMID:15336702 PMID:15483189 PMID:15994225 PMID:17505938 PMID:17804755 PMID:18324785 PMID:21543282 PMID:23562765 PMID:27473015 PMID:28751236 PMID:33049310 More...
|
|
NCBI chr X:67,135,317...67,304,476
Ensembl chr X:67,135,317...67,304,467
|
|
| G
|
Bloc1s1
|
biogenesis of lysosomal organelles complex-1, subunit 1
|
multiple interactions
|
ISO
|
[Cyproterone Acetate binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to BLOC1S1 protein modified form]
|
CTD |
PMID:28751236 |
|
NCBI chr 7:1,347,495...1,351,103
Ensembl chr 7:1,925,335...1,936,049
|
|
| G
|
Brd8
|
bromodomain containing 8
|
multiple interactions
|
ISO
|
[Cyproterone Acetate binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to BRD8 protein modified form]
|
CTD |
PMID:28751236 |
|
NCBI chr18:26,455,824...26,504,106
Ensembl chr18:26,455,512...26,504,006
|
|
| G
|
Ccr1
|
C-C motif chemokine receptor 1
|
multiple interactions
|
ISO
|
[Ethinyl Estradiol co-treated with Cyproterone Acetate] results in increased expression of CCR1 protein
|
CTD |
PMID:10770211 |
|
NCBI chr 8:132,433,711...132,439,266
Ensembl chr 8:132,431,592...132,439,374
|
|
| G
|
Ccr5
|
C-C motif chemokine receptor 5
|
multiple interactions
|
ISO
|
[Ethinyl Estradiol co-treated with Cyproterone Acetate] results in increased expression of CCR5 protein
|
CTD |
PMID:10770211 |
|
NCBI chr 8:132,629,097...132,660,980
Ensembl chr 8:132,629,683...132,637,594
|
|
| G
|
Chd9
|
chromodomain helicase DNA binding protein 9
|
multiple interactions
|
ISO
|
[Cyproterone Acetate binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to CHD9 protein modified form]
|
CTD |
PMID:28751236 |
|
NCBI chr19:15,941,535...16,146,220
Ensembl chr19:32,115,920...32,319,042
|
|
| G
|
Cnot1
|
CCR4-NOT transcription complex, subunit 1
|
multiple interactions
|
ISO
|
[Cyproterone Acetate binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to CNOT1 protein modified form]
|
CTD |
PMID:28751236 |
|
NCBI chr19:9,261,290...9,352,636
Ensembl chr19:9,261,294...9,352,636
|
|
| G
|
Crebbp
|
CREB binding protein
|
multiple interactions
|
ISO
|
[Cyproterone Acetate binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to CREBBP protein modified form]; [Cyproterone Acetate binds to AR protein] promotes the reaction [CREBBP protein binds to KLK3 enhancer]; [Cyproterone Acetate binds to AR protein] promotes the reaction [CREBBP protein binds to KLK3 promoter]
|
CTD |
PMID:15308689 PMID:28751236 |
|
NCBI chr10:11,842,307...11,968,266
Ensembl chr10:11,822,620...11,968,266
|
|
| G
|
Crp
|
C-reactive protein
|
multiple interactions
|
ISO
|
[Ethinyl Estradiol co-treated with Cyproterone Acetate] results in increased expression of CRP protein
|
CTD |
PMID:14557435 |
|
NCBI chr13:87,694,062...87,695,978
Ensembl chr13:87,657,317...87,707,514
|
|
| G
|
Cxcr3
|
C-X-C motif chemokine receptor 3
|
multiple interactions
|
ISO
|
[Ethinyl Estradiol co-treated with Cyproterone Acetate] results in increased expression of CXCR3 protein
|
CTD |
PMID:10770211 |
|
NCBI chr X:70,884,293...70,886,944
Ensembl chr X:70,883,958...70,886,871
|
|
| G
|
Cyp1a1
|
cytochrome P450, family 1, subfamily a, polypeptide 1
|
decreases activity
|
ISO
|
Cyproterone Acetate results in decreased activity of CYP1A1 protein
|
CTD |
PMID:34181028 |
|
NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012
|
|
| G
|
Cyp2b3
|
cytochrome P450, family 2, subfamily b, polypeptide 3
|
increases expression
|
ISO
|
Cyproterone Acetate results in increased expression of CYP2B10 mRNA
|
CTD |
PMID:28541575 |
|
NCBI chr 1:90,780,468...90,859,852
|
|
| G
|
Cyp2c24
|
cytochrome P450, family 2, subfamily c, polypeptide 24
|
increases expression
|
ISO
|
Cyproterone Acetate results in increased expression of CYP2C55 mRNA
|
CTD |
PMID:28541575 |
|
NCBI chr 1:246,286,341...246,348,607
Ensembl chr 1:246,286,341...246,348,607
|
|
| G
|
Cyp3a2
|
cytochrome P450, family 3, subfamily a, polypeptide 2
|
increases expression
|
ISO
|
Cyproterone Acetate results in increased expression of CYP3A4 mRNA
|
CTD |
PMID:12505310 |
|
NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857
|
|
| G
|
Dhx30
|
DExH-box helicase 30
|
multiple interactions
|
ISO
|
[Cyproterone Acetate binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to DHX30 protein modified form]
|
CTD |
PMID:28751236 |
|
NCBI chr 8:110,064,751...110,096,954
Ensembl chr 8:118,943,187...118,975,592
|
|
| G
|
Egf
|
epidermal growth factor
|
multiple interactions
|
EXP
|
[EGF protein co-treated with Cyproterone Acetate] results in increased expression of MYC mRNA
|
CTD |
PMID:12632255 |
|
NCBI chr 2:220,893,660...220,976,331
Ensembl chr 2:220,893,660...220,976,297
|
|
| G
|
Ep300
|
E1A binding protein p300
|
multiple interactions
|
ISO
|
[Cyproterone Acetate binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to EP300 protein modified form]
|
CTD |
PMID:28751236 |
|
NCBI chr 7:114,987,857...115,058,652
Ensembl chr 7:114,946,982...115,058,574
|
|
| G
|
Esr1
|
estrogen receptor 1
|
multiple interactions
|
ISO
|
Cyproterone Acetate binds to and results in increased activity of ESR1 protein
|
CTD |
PMID:33049310 |
|
NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:43,644,392...43,900,354
|
|
| G
|
Esr2
|
estrogen receptor 2
|
multiple interactions
|
ISO
|
Cyproterone Acetate binds to and results in increased activity of ESR2 protein
|
CTD |
PMID:33049310 |
|
NCBI chr 6:100,589,553...100,645,240
Ensembl chr 6:100,545,206...100,644,709
|
|
| G
|
Fabp4
|
fatty acid binding protein 4
|
multiple interactions
|
ISO
|
[Cyproterone Acetate co-treated with Rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of FABP4 protein; Cyproterone Acetate inhibits the reaction [[Dexamethasone co-treated with Rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of FABP4 protein]
|
CTD |
PMID:29782964 |
|
NCBI chr 2:93,488,251...93,492,961
Ensembl chr 2:93,488,271...93,492,972
|
|
| G
|
Fshb
|
follicle stimulating hormone subunit beta
|
multiple interactions decreases expression
|
ISO
|
[Ethinyl Estradiol co-treated with Cyproterone Acetate] results in decreased expression of FSHB protein Cyproterone Acetate results in decreased expression of FSHB protein
|
CTD |
PMID:11994349 PMID:16002536 |
|
NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:114,003,262...114,007,072
|
|
| G
|
Gnaq
|
G protein subunit alpha q
|
multiple interactions
|
ISO
|
[Cyproterone Acetate binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to GNAQ protein modified form]
|
CTD |
PMID:28751236 |
|
NCBI chr 1:222,852,453...223,098,754
Ensembl chr 1:222,852,097...223,126,742
|
|
| G
|
Greb1
|
growth regulating estrogen receptor binding 1
|
multiple interactions
|
ISO
|
Cyproterone Acetate inhibits the reaction [Testosterone results in increased expression of GREB1 mRNA]
|
CTD |
PMID:16496412 |
|
NCBI chr 6:45,169,289...45,321,973
Ensembl chr 6:45,169,289...45,291,126
|
|
| G
|
Helz2
|
helicase with zinc finger 2
|
multiple interactions
|
ISO
|
[Cyproterone Acetate binds to and affects the folding of AR protein] inhibits the reaction [AR protein modified form binds to HELZ2 protein modified form]
|
CTD |
PMID:28751236 |
|
NCBI chr 3:168,338,813...168,353,219
Ensembl chr 3:188,716,370...188,730,716
|
|
| G
|
Hsd3b5
|
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5
|
increases expression multiple interactions
|
EXP
|
Cyproterone Acetate results in increased expression of HSD3B5 mRNA [Cyproterone Acetate co-treated with Testosterone] results in increased expression of HSD3B5 mRNA
|
CTD |
PMID:25603467 |
|
NCBI chr 2:188,697,669...188,717,141
Ensembl chr 2:188,697,670...188,709,118
|
|
| G
|
Igf1
|
insulin-like growth factor 1
|
multiple interactions
|
ISO
|
[Ethinyl Estradiol co-treated with Cyproterone Acetate] results in decreased expression of IGF1 protein
|
CTD |
PMID:16002536 |
|
NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:24,130,137...24,246,764
|
|
| G
|
Ins2
|
insulin 2
|
multiple interactions
|
ISO
|
[Cyproterone Acetate co-treated with Rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of FABP4 protein; Cyproterone Acetate inhibits the reaction [[Dexamethasone co-treated with Rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of and results in increased secretion of ADIPOQ protein]; Cyproterone Acetate inhibits the reaction [[Dexamethasone co-treated with Rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of FABP4 protein]
|
CTD |
PMID:29782964 |
|
NCBI chr 1:207,272,738...207,421,998
Ensembl chr 1:207,272,742...207,273,805
|
|
| G
|
Itgb3bp
|
integrin subunit beta 3 binding protein
|
multiple interactions
|
ISO
|
[Cyproterone Acetate binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to ITGB3BP protein modified form]
|
CTD |
PMID:28751236 |
|
NCBI chr 5:119,575,657...119,640,974
Ensembl chr 5:119,575,248...119,640,997
|
|
| G
|
Kif11
|
kinesin family member 11
|
multiple interactions
|
ISO
|
[Cyproterone Acetate binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to KIF11 protein modified form]
|
CTD |
PMID:28751236 |
|
NCBI chr 1:244,494,916...244,589,250
Ensembl chr 1:244,494,875...244,589,250
|
|
| G
|
Klk1c10
|
kallikrein 1-related peptidase C10
|
affects binding decreases expression multiple interactions
|
ISO
|
[Cyproterone Acetate binds to AR protein] which binds to KLK3 enhancer; [Cyproterone Acetate binds to AR protein] which binds to KLK3 promoter Cyproterone Acetate results in decreased expression of KLK3 protein [Cyproterone Acetate binds to AR protein] promotes the reaction [CREBBP protein binds to KLK3 enhancer]; [Cyproterone Acetate binds to AR protein] promotes the reaction [CREBBP protein binds to KLK3 promoter]; [Cyproterone Acetate binds to AR protein] promotes the reaction [NCOA2 protein binds to KLK3 enhancer]; [Cyproterone Acetate binds to AR protein] promotes the reaction [NCOA2 protein binds to KLK3 promoter]; [Cyproterone Acetate binds to AR protein] promotes the reaction [NCOR1 protein binds to KLK3 promoter]; [Cyproterone Acetate co-treated with Estradiol] results in decreased expression of KLK3 protein; [Cyproterone Acetate co-treated with Ethinyl Estradiol] results in decreased expression of KLK3 protein; Cyproterone Acetate inhibits the reaction [[Dihydrotestosterone binds to and results in increased activity of AR protein] which results in increased expression of KLK3 protein]; Cyproterone Acetate inhibits the reaction [[Metribolone binds to and results in increased activity of AR protein] which results in increased expression of KLK3 protein]
|
CTD |
PMID:10687981 PMID:15308689 PMID:15336702 |
|
NCBI chr 1:94,402,993...94,407,052
Ensembl chr 1:103,539,527...103,543,586
|
|
| G
|
Kpna1
|
karyopherin subunit alpha 1
|
increases expression
|
EXP
|
Cyproterone Acetate results in increased expression of KPNA1 mRNA
|
CTD |
PMID:16906019 |
|
NCBI chr11:64,715,844...64,774,647
Ensembl chr11:78,222,884...78,267,067
|
|
| G
|
Kpna2
|
karyopherin subunit alpha 2
|
decreases expression increases expression
|
EXP
|
Cyproterone Acetate results in decreased expression of KPNA2 mRNA Cyproterone Acetate results in increased expression of KPNA2 mRNA
|
CTD |
PMID:16906019 |
|
NCBI chr10:92,433,678...92,445,841
Ensembl chr10:92,433,679...92,445,937
|
|
| G
|
Kpna3
|
karyopherin subunit alpha 3
|
increases expression
|
EXP
|
Cyproterone Acetate results in increased expression of KPNA3 mRNA
|
CTD |
PMID:16906019 |
|
NCBI chr15:35,536,310...35,610,066
Ensembl chr15:39,712,381...39,786,319
|
|
| G
|
Kpna4
|
karyopherin subunit alpha 4
|
decreases expression
|
EXP
|
Cyproterone Acetate results in decreased expression of KPNA4 mRNA
|
CTD |
PMID:16906019 |
|
NCBI chr 2:153,319,380...153,381,085
Ensembl chr 2:155,634,247...155,691,053
|
|
| G
|
Kpna5
|
karyopherin subunit alpha 5
|
decreases expression
|
EXP
|
Cyproterone Acetate results in decreased expression of KPNA5 mRNA
|
CTD |
PMID:16906019 |
|
NCBI chr20:31,365,647...31,430,793
Ensembl chr20:31,365,656...31,430,792
|
|
| G
|
Lhb
|
luteinizing hormone subunit beta
|
decreases expression multiple interactions increases expression
|
ISO EXP
|
Cyproterone Acetate results in decreased expression of LHB protein Cyproterone Acetate inhibits the reaction [testosterone enanthate results in decreased expression of LHB protein] Cyproterone Acetate results in increased expression of LHB protein [Ethinyl Estradiol co-treated with Cyproterone Acetate] results in decreased expression of LHB protein
|
CTD |
PMID:11994349 PMID:16002536 PMID:20463352 PMID:23085480 |
|
NCBI chr 1:105,037,457...105,038,446
Ensembl chr 1:105,037,457...105,038,445
|
|
| G
|
Med1
|
mediator complex subunit 1
|
multiple interactions
|
ISO
|
[Cyproterone Acetate binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to MED1 protein modified form]
|
CTD |
PMID:28751236 |
|
NCBI chr10:83,641,851...83,685,560
Ensembl chr10:83,641,862...83,685,545
|
|
| G
|
Men1
|
menin 1
|
multiple interactions
|
ISO
|
[Cyproterone Acetate binds to and affects the folding of AR protein] inhibits the reaction [AR protein modified form binds to MEN1 protein modified form]
|
CTD |
PMID:28751236 |
|
NCBI chr 1:203,638,905...203,644,871
Ensembl chr 1:213,068,166...213,074,120
|
|
| G
|
Mta1
|
metastasis associated 1
|
multiple interactions
|
ISO
|
[Cyproterone Acetate binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to MTA1 protein modified form]
|
CTD |
PMID:28751236 |
|
NCBI chr 6:137,999,845...138,038,696
Ensembl chr 6:137,999,915...138,038,696
|
|
| G
|
Myc
|
MYC proto-oncogene, bHLH transcription factor
|
multiple interactions
|
EXP
|
[EGF protein co-treated with Cyproterone Acetate] results in increased expression of MYC mRNA
|
CTD |
PMID:12632255 |
|
NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:95,483,105...95,488,028
|
|
| G
|
Ncoa1
|
nuclear receptor coactivator 1
|
multiple interactions
|
ISO
|
NCOA1 protein results in increased activity of [Cyproterone Acetate binds to AR protein]
|
CTD |
PMID:17804755 |
|
NCBI chr 6:32,952,090...33,229,829
Ensembl chr 6:32,952,090...33,195,924
|
|
| G
|
Ncoa2
|
nuclear receptor coactivator 2
|
multiple interactions
|
ISO
|
[Cyproterone Acetate binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to NCOA2 protein modified form]; [Cyproterone Acetate binds to AR protein] promotes the reaction [NCOA2 protein binds to KLK3 enhancer]; [Cyproterone Acetate binds to AR protein] promotes the reaction [NCOA2 protein binds to KLK3 promoter]
|
CTD |
PMID:15308689 PMID:28751236 |
|
NCBI chr 5:5,835,642...6,069,693
Ensembl chr 5:10,618,722...10,852,776
|
|
| G
|
Ncoa3
|
nuclear receptor coactivator 3
|
multiple interactions
|
ISO
|
[Cyproterone Acetate binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to NCOA3 protein modified form]
|
CTD |
PMID:28751236 |
|
NCBI chr 3:175,157,824...175,237,831
Ensembl chr 3:175,157,821...175,240,631
|
|
| G
|
Ncor1
|
nuclear receptor co-repressor 1
|
multiple interactions
|
ISO
|
[Cyproterone Acetate binds to and affects the folding of AR protein] inhibits the reaction [AR protein modified form binds to NCOR1 protein modified form]; [Cyproterone Acetate binds to AR protein] promotes the reaction [NCOR1 protein binds to KLK3 promoter]
|
CTD |
PMID:15308689 PMID:28751236 |
|
NCBI chr10:47,498,852...47,641,612
Ensembl chr10:47,498,852...47,640,350
|
|
| G
|
Nfe2l2
|
NFE2 like bZIP transcription factor 2
|
increases activity
|
ISO
|
Cyproterone Acetate results in increased activity of NFE2L2 protein
|
CTD |
PMID:30203046 |
|
NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090
|
|
| G
|
Nfkbib
|
NFKB inhibitor beta
|
multiple interactions
|
ISO
|
[Cyproterone Acetate binds to and affects the folding of AR protein] affects the reaction [AR protein modified form binds to NFKBIB protein modified form]
|
CTD |
PMID:28751236 |
|
NCBI chr 1:93,173,817...93,181,387
Ensembl chr 1:93,173,820...93,326,366
|
|
| G
|
Nos2
|
nitric oxide synthase 2
|
multiple interactions decreases expression
|
EXP
|
Cyproterone Acetate inhibits the reaction [testosterone enanthate results in increased expression of NOS2 mRNA]; Cyproterone Acetate inhibits the reaction [testosterone enanthate results in increased expression of NOS2 protein] Cyproterone Acetate results in decreased expression of NOS2 mRNA
|
CTD |
PMID:20463352 PMID:23085480 |
|
NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880
|
|
| G
|
Nr0b1
|
nuclear receptor subfamily 0, group B, member 1
|
multiple interactions
|
ISO
|
[Cyproterone Acetate binds to and affects the folding of AR protein] affects the reaction [AR protein modified form binds to NR0B1 protein modified form]
|
CTD |
PMID:28751236 |
|
NCBI chr X:50,756,886...50,761,014
Ensembl chr X:54,707,639...54,712,083
|
|
| G
|
Nr0b2
|
nuclear receptor subfamily 0, group B, member 2
|
multiple interactions
|
ISO
|
[Cyproterone Acetate binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to NR0B2 protein modified form]
|
CTD |
PMID:28751236 |
|
NCBI chr 5:151,063,160...151,066,475
Ensembl chr 5:151,063,160...151,066,475
|
|
| G
|
Nr1i2
|
nuclear receptor subfamily 1, group I, member 2
|
multiple interactions
|
ISO
|
Cyproterone Acetate binds to and results in increased activity of NR1I2 protein
|
CTD |
PMID:33049310 |
|
NCBI chr11:75,965,717...76,006,733
Ensembl chr11:75,965,632...76,002,380
|
|
| G
|
Nr1i3
|
nuclear receptor subfamily 1, group I, member 3
|
increases activity
|
ISO
|
Cyproterone Acetate results in increased activity of NR1I3 protein
|
CTD |
PMID:30203046 |
|
NCBI chr13:83,632,940...83,638,193
Ensembl chr13:86,165,349...86,170,370
|
|
| G
|
Nrbf2
|
nuclear receptor binding factor 2
|
multiple interactions
|
ISO
|
[Cyproterone Acetate binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to NRBF2 protein modified form]
|
CTD |
PMID:28751236 |
|
NCBI chr20:21,308,555...21,326,881
Ensembl chr20:21,290,787...21,325,724
|
|
| G
|
Nrip1
|
nuclear receptor interacting protein 1
|
multiple interactions
|
ISO
|
[Cyproterone Acetate binds to and affects the folding of AR protein] inhibits the reaction [AR protein modified form binds to NRIP1 protein modified form]
|
CTD |
PMID:28751236 |
|
NCBI chr11:14,895,843...14,979,490
Ensembl chr11:28,378,878...28,467,353
|
|
| G
|
Pa2g4
|
proliferation-associated 2G4
|
multiple interactions
|
ISO
|
PA2G4 protein inhibits the reaction [Cyproterone Acetate promotes the reaction [Metribolone results in increased expression of AR mRNA]]; PA2G4 protein inhibits the reaction [Cyproterone Acetate results in increased expression of AR mRNA]
|
CTD |
PMID:15994225 |
|
NCBI chr 7:984,795...992,264
Ensembl chr 7:1,569,327...1,576,802
|
|
| G
|
Pbsn
|
probasin
|
multiple interactions
|
EXP
|
Cyproterone Acetate inhibits the reaction [Cadmium Chloride results in increased expression of PBSN mRNA]
|
CTD |
PMID:11751618 |
|
NCBI chr X:41,914,346...41,929,591
Ensembl chr X:45,792,738...45,807,983
|
|
| G
|
Pde5a
|
phosphodiesterase 5A
|
multiple interactions
|
EXP
|
Cyproterone Acetate inhibits the reaction [testosterone enanthate results in increased expression of PDE5A mRNA]
|
CTD |
PMID:20463352 |
|
NCBI chr 2:213,542,822...213,687,638
Ensembl chr 2:213,542,923...213,684,298
|
|
| G
|
Pelp1
|
proline, glutamate and leucine rich protein 1
|
multiple interactions
|
ISO
|
[Cyproterone Acetate binds to and affects the folding of AR protein] inhibits the reaction [AR protein modified form binds to PELP1 protein modified form]
|
CTD |
PMID:28751236 |
|
NCBI chr10:55,593,444...55,610,478
Ensembl chr10:55,593,447...55,610,758
|
|
| G
|
Pgr
|
progesterone receptor
|
multiple interactions
|
ISO
|
[Cyproterone Acetate binds to and affects the folding of AR protein] inhibits the reaction [AR protein modified form binds to PGR protein modified form]; Cyproterone Acetate binds to and results in increased activity of PGR protein
|
CTD |
PMID:20599585 PMID:28751236 |
|
NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:14,354,398...14,413,271
|
|
| G
|
Pnrc2
|
proline-rich nuclear receptor coactivator 2
|
multiple interactions
|
ISO
|
[Cyproterone Acetate binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to PNRC2 protein modified form]
|
CTD |
PMID:28751236 |
|
NCBI chr 5:148,103,966...148,106,950
Ensembl chr 5:153,378,863...153,390,748
|
|
| G
|
Pparg
|
peroxisome proliferator-activated receptor gamma
|
multiple interactions
|
ISO
|
Cyproterone Acetate binds to and results in increased activity of PPARG protein
|
CTD |
PMID:33049310 |
|
NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104
|
|
| G
|
Pprc1
|
PPARG related coactivator 1
|
multiple interactions
|
ISO
|
[Cyproterone Acetate binds to and affects the folding of AR protein] inhibits the reaction [AR protein modified form binds to PPRC1 protein modified form]
|
CTD |
PMID:28751236 |
|
NCBI chr 1:254,851,136...254,867,570
Ensembl chr 1:254,851,164...254,867,570
|
|
| G
|
Pramex1
|
PRAME like, X-linked 1
|
multiple interactions
|
ISO
|
[Cyproterone Acetate binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to PRAME protein modified form]
|
CTD |
PMID:28751236 |
|
NCBI chr X:102,862,457...102,867,725
Ensembl chr X:102,861,881...102,870,708
|
|
| G
|
Prl
|
prolactin
|
multiple interactions
|
ISO EXP
|
[Cyproterone Acetate co-treated with Ethinyl Estradiol] results in decreased expression of PRL protein Cyproterone Acetate inhibits the reaction [Testosterone results in decreased expression of PRL mRNA]
|
CTD |
PMID:3157511 PMID:25603467 |
|
NCBI chr17:38,287,355...38,298,234
Ensembl chr17:38,288,162...38,298,217
|
|
| G
|
Prlr
|
prolactin receptor
|
multiple interactions increases expression
|
EXP
|
[Cyproterone Acetate co-treated with Testosterone] results in increased expression of PRLR mRNA Cyproterone Acetate results in increased expression of PRLR mRNA
|
CTD |
PMID:25603467 |
|
NCBI chr 2:60,861,391...61,051,883
Ensembl chr 2:60,861,658...61,051,882
|
|
| G
|
Tfrc
|
transferrin receptor
|
multiple interactions
|
ISO
|
[Ethinyl Estradiol co-treated with Cyproterone Acetate] results in decreased expression of TFRC protein
|
CTD |
PMID:16002536 |
|
NCBI chr11:81,668,478...81,690,318
Ensembl chr11:81,668,478...81,690,318
|
|
| G
|
Tgfb1i1
|
transforming growth factor beta 1 induced transcript 1
|
multiple interactions
|
ISO
|
[Cyproterone Acetate binds to and affects the folding of AR protein] inhibits the reaction [AR protein modified form binds to TGFB1I1 protein modified form]
|
CTD |
PMID:28751236 |
|
NCBI chr 1:182,828,553...182,835,465
Ensembl chr 1:192,258,598...192,265,903
|
|
| G
|
Trerf1
|
transcriptional regulating factor 1
|
multiple interactions
|
ISO
|
[Cyproterone Acetate binds to and affects the folding of AR protein] inhibits the reaction [AR protein modified form binds to TRERF1 protein modified form]
|
CTD |
PMID:28751236 |
|
NCBI chr 9:13,631,619...13,858,326
Ensembl chr 9:21,131,777...21,176,016
|
|
| G
|
Ube3a
|
ubiquitin protein ligase E3A
|
multiple interactions
|
ISO
|
[Cyproterone Acetate binds to and affects the folding of AR protein] inhibits the reaction [AR protein modified form binds to UBE3A protein modified form]
|
CTD |
PMID:28751236 |
|
NCBI chr 1:119,204,244...119,297,097
Ensembl chr 1:119,206,148...119,297,097
|
|
|
|
| G
|
Akr1c3
|
aldo-keto reductase family 1, member C3
|
decreases activity
|
ISO
|
Desogestrel results in decreased activity of AKR1C3 protein
|
CTD |
PMID:21182831 |
|
NCBI chr17:71,020,884...71,037,779
Ensembl chr17:70,970,900...71,048,438
|
|
| G
|
Apoe
|
apolipoprotein E
|
multiple interactions
|
ISO
|
[cetrorelix co-treated with testosterone enanthate co-treated with Desogestrel] results in decreased expression of APOE mRNA
|
CTD |
PMID:18160741 |
|
NCBI chr 1:88,481,889...88,485,816
Ensembl chr 1:88,481,385...88,485,855
|
|
| G
|
Cat
|
catalase
|
multiple interactions
|
ISO
|
[Ethinyl Estradiol co-treated with Desogestrel] results in decreased activity of CAT protein
|
CTD |
PMID:17541152 |
|
NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526
|
|
| G
|
Ccn5
|
cellular communication network factor 5
|
multiple interactions
|
ISO
|
[cetrorelix co-treated with testosterone enanthate co-treated with Desogestrel] results in decreased expression of CCN5 mRNA
|
CTD |
PMID:18160741 |
|
NCBI chr 3:172,910,670...172,922,064
Ensembl chr 3:172,910,681...172,922,062
|
|
| G
|
Cpb2
|
carboxypeptidase B2
|
increases activity
|
ISO
|
Desogestrel results in increased activity of CPB2 protein
|
CTD |
PMID:11301170 |
|
NCBI chr15:56,967,128...57,015,964
Ensembl chr15:56,966,839...57,015,962
|
|
| G
|
Crp
|
C-reactive protein
|
multiple interactions
|
ISO
|
[Ethinyl Estradiol co-treated with Desogestrel] results in increased expression of CRP protein; Simvastatin inhibits the reaction [[Ethinyl Estradiol co-treated with Desogestrel] results in increased expression of CRP protein]
|
CTD |
PMID:17105841 |
|
NCBI chr13:87,694,062...87,695,978
Ensembl chr13:87,657,317...87,707,514
|
|
| G
|
Cst9l
|
cystatin 9-like
|
multiple interactions
|
ISO
|
[cetrorelix co-treated with testosterone enanthate co-treated with Desogestrel] results in increased expression of CST9L mRNA
|
CTD |
PMID:18160741 |
|
NCBI chr 3:136,288,093...136,290,906
Ensembl chr 3:156,741,232...156,744,045
|
|
| G
|
Cyp11a1
|
cytochrome P450, family 11, subfamily a, polypeptide 1
|
multiple interactions
|
ISO
|
[cetrorelix co-treated with testosterone enanthate co-treated with Desogestrel] results in decreased expression of CYP11A1 mRNA
|
CTD |
PMID:18160741 |
|
NCBI chr 8:67,318,665...67,330,196
Ensembl chr 8:67,270,556...67,330,196
|
|
| G
|
Cyp17a1
|
cytochrome P450, family 17, subfamily a, polypeptide 1
|
multiple interactions
|
ISO
|
[cetrorelix co-treated with testosterone enanthate co-treated with Desogestrel] results in decreased expression of CYP17A1 mRNA
|
CTD |
PMID:18160741 |
|
NCBI chr 1:255,476,861...255,484,547
Ensembl chr 1:255,476,861...255,482,974
|
|
| G
|
Cyp1a2
|
cytochrome P450, family 1, subfamily a, polypeptide 2
|
decreases activity
|
ISO
|
Desogestrel results in decreased activity of CYP1A2 protein
|
CTD |
PMID:18816299 |
|
NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:66,971,261...66,978,149
|
|
| G
|
Ddr1
|
discoidin domain receptor tyrosine kinase 1
|
multiple interactions
|
ISO
|
[cetrorelix co-treated with testosterone enanthate co-treated with Desogestrel] results in increased expression of DDR1 mRNA
|
CTD |
PMID:18160741 |
|
NCBI chr20:3,042,494...3,064,442
Ensembl chr20:3,050,375...3,069,276
|
|
| G
|
Dhcr24
|
24-dehydrocholesterol reductase
|
multiple interactions
|
ISO
|
[cetrorelix co-treated with testosterone enanthate co-treated with Desogestrel] results in decreased expression of DHCR24 mRNA
|
CTD |
PMID:18160741 |
|
NCBI chr 5:126,573,366...126,599,940
Ensembl chr 5:126,573,338...126,599,936
|
|
| G
|
Dpep3
|
dipeptidase 3
|
multiple interactions
|
ISO
|
[cetrorelix co-treated with testosterone enanthate co-treated with Desogestrel] results in decreased expression of DPEP3 mRNA
|
CTD |
PMID:18160741 |
|
NCBI chr19:50,778,079...50,786,451
Ensembl chr19:50,777,579...50,783,741
|
|
| G
|
Hmgcs2
|
3-hydroxy-3-methylglutaryl-CoA synthase 2
|
multiple interactions
|
ISO
|
[cetrorelix co-treated with testosterone enanthate co-treated with Desogestrel] results in decreased expression of HMGCS2 mRNA
|
CTD |
PMID:18160741 |
|
NCBI chr 2:188,564,348...188,590,872
Ensembl chr 2:188,547,767...188,592,242
|
|
| G
|
Insl3
|
insulin-like 3
|
multiple interactions
|
ISO
|
[cetrorelix co-treated with testosterone enanthate co-treated with Desogestrel] results in decreased expression of INSL3 mRNA
|
CTD |
PMID:18160741 |
|
NCBI chr16:18,432,668...18,434,539
|
|
| G
|
Ldlr
|
low density lipoprotein receptor
|
multiple interactions increases expression
|
ISO
|
[Desogestrel co-treated with Ethinyl Estradiol] results in increased expression of LDLR protein Desogestrel results in increased expression of LDLR protein
|
CTD |
PMID:17900441 |
|
NCBI chr 8:28,546,191...28,569,075
Ensembl chr 8:28,546,146...28,570,675
|
|
| G
|
Lhb
|
luteinizing hormone subunit beta
|
multiple interactions
|
ISO
|
[Ethinyl Estradiol co-treated with Desogestrel] results in decreased expression of LHB protein; Simvastatin promotes the reaction [[Ethinyl Estradiol co-treated with Desogestrel] results in decreased expression of LHB protein]
|
CTD |
PMID:17105841 |
|
NCBI chr 1:105,037,457...105,038,446
Ensembl chr 1:105,037,457...105,038,445
|
|
| G
|
Papss2
|
3'-phosphoadenosine 5'-phosphosulfate synthase 2
|
multiple interactions
|
ISO
|
[cetrorelix co-treated with testosterone enanthate co-treated with Desogestrel] results in decreased expression of PAPSS2 mRNA
|
CTD |
PMID:18160741 |
|
NCBI chr 1:239,867,597...239,952,614
Ensembl chr 1:239,867,574...239,952,616
|
|
| G
|
Pgr
|
progesterone receptor
|
multiple interactions
|
ISO
|
Desogestrel binds to and affects the activity of PGR protein
|
CTD |
PMID:15697108 |
|
NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:14,354,398...14,413,271
|
|
| G
|
Pgrmc1
|
progesterone receptor membrane component 1
|
multiple interactions
|
ISO
|
[cetrorelix co-treated with testosterone enanthate co-treated with Desogestrel] results in decreased expression of PGRMC1 mRNA
|
CTD |
PMID:18160741 |
|
NCBI chr X:120,698,610...120,706,805
Ensembl chr X:120,698,610...120,706,805
|
|
| G
|
Pon1
|
paraoxonase 1
|
multiple interactions
|
ISO
|
[Ethinyl Estradiol co-treated with Desogestrel] affects the activity of PON1 protein
|
CTD |
PMID:17541152 |
|
NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:34,261,289...34,287,924
|
|
| G
|
Proc
|
protein C, inactivator of coagulation factors Va and VIIIa
|
decreases activity
|
ISO
|
Desogestrel results in decreased activity of PROC protein
|
CTD |
PMID:11301170 |
|
NCBI chr18:24,038,596...24,049,061
Ensembl chr18:24,038,597...24,048,964
|
|
| G
|
Prok1
|
prokineticin 1
|
multiple interactions
|
ISO
|
[cetrorelix co-treated with testosterone enanthate co-treated with Desogestrel] results in decreased expression of PROK1 mRNA
|
CTD |
PMID:18160741 |
|
NCBI chr 2:197,538,747...197,547,550
Ensembl chr 2:197,537,068...197,547,550
|
|
| G
|
Pros1
|
protein S
|
affects expression
|
ISO
|
Desogestrel affects the expression of PROS1 protein
|
CTD |
PMID:11442481 |
|
NCBI chr11:230,597...311,288
Ensembl chr11:13,676,769...13,757,852
|
|
| G
|
Rhob
|
ras homolog family member B
|
multiple interactions
|
ISO
|
[cetrorelix co-treated with testosterone enanthate co-treated with Desogestrel] results in decreased expression of RHOB mRNA
|
CTD |
PMID:18160741 |
|
NCBI chr 6:37,083,030...37,085,204
Ensembl chr 6:37,075,015...37,112,772
|
|
| G
|
Sycp1
|
synaptonemal complex protein 1
|
multiple interactions
|
ISO
|
[cetrorelix co-treated with testosterone enanthate co-treated with Desogestrel] results in decreased expression of SYCP1 mRNA
|
CTD |
PMID:18160741 |
|
NCBI chr 2:192,985,164...193,145,234
Ensembl chr 2:192,984,621...193,145,421
|
|
| G
|
Taf4b
|
TATA-box binding protein associated factor 4b
|
multiple interactions
|
ISO
|
[cetrorelix co-treated with testosterone enanthate co-treated with Desogestrel] results in decreased expression of TAF4B mRNA
|
CTD |
PMID:18160741 |
|
NCBI chr18:6,227,299...6,360,970
Ensembl chr18:6,227,345...6,356,275
|
|
| G
|
Tex19.2
|
testis expressed gene 19.2
|
multiple interactions
|
ISO
|
[cetrorelix co-treated with testosterone enanthate co-treated with Desogestrel] results in decreased expression of TEX19 mRNA
|
CTD |
PMID:18160741 |
|
NCBI chr10:106,878,083...106,880,671
Ensembl chr10:106,878,085...106,880,671
|
|
| G
|
Vcam1
|
vascular cell adhesion molecule 1
|
multiple interactions
|
ISO
|
[Ethinyl Estradiol co-treated with Desogestrel] results in decreased expression of VCAM1 protein; Simvastatin promotes the reaction [[Ethinyl Estradiol co-treated with Desogestrel] results in decreased expression of VCAM1 protein]
|
CTD |
PMID:17105841 |
|
NCBI chr 2:206,723,050...206,742,783
Ensembl chr 2:206,723,044...206,742,801
|
|
|
|
| G
|
Akr1c1
|
aldo-keto reductase family 1, member C1
|
decreases expression
|
ISO
|
dienogest results in decreased expression of AKR1C1 mRNA
|
CTD |
PMID:23183084 |
|
NCBI chr17:70,720,397...70,747,285
Ensembl chr17:70,720,398...70,747,247
|
|
| G
|
Akr1c2
|
aldo-keto reductase family 1, member C2
|
decreases expression
|
ISO
|
dienogest results in decreased expression of AKR1C2 mRNA
|
CTD |
PMID:23183084 |
|
NCBI chr17:70,669,684...70,717,935
Ensembl chr17:70,669,710...70,685,686
|
|
| G
|
Ccl2
|
C-C motif chemokine ligand 2
|
multiple interactions
|
ISO
|
dienogest inhibits the reaction [[Lipopolysaccharides co-treated with HMGB1 protein] results in increased expression of CCL2 protein]
|
CTD |
PMID:22014880 |
|
NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875
|
|
| G
|
Cd4
|
Cd4 molecule
|
multiple interactions
|
ISO
|
[Ethinyl Estradiol co-treated with dienogest] results in decreased expression of CD4 protein
|
CTD |
PMID:10813102 |
|
NCBI chr 4:159,355,147...159,381,636
Ensembl chr 4:159,356,337...159,381,461
|
|
| G
|
Crp
|
C-reactive protein
|
multiple interactions
|
ISO
|
[Estradiol co-treated with dienogest] results in increased expression of CRP protein
|
CTD |
PMID:15970291 |
|
NCBI chr13:87,694,062...87,695,978
Ensembl chr13:87,657,317...87,707,514
|
|
| G
|
Cyp19a1
|
cytochrome P450, family 19, subfamily a, polypeptide 1
|
decreases expression
|
ISO
|
dienogest results in decreased expression of CYP19A1 mRNA; dienogest results in decreased expression of CYP19A1 protein
|
CTD |
PMID:22130322 |
|
NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:63,449,148...63,476,917
|
|
| G
|
F2
|
coagulation factor II, thrombin
|
multiple interactions
|
ISO
|
[Ethinyl Estradiol co-treated with dienogest] results in increased expression of F2 protein
|
CTD |
PMID:15288212 |
|
NCBI chr 3:98,051,958...98,065,246
Ensembl chr 3:98,051,960...98,065,246
|
|
| G
|
F7
|
coagulation factor VII
|
multiple interactions
|
ISO
|
[Ethinyl Estradiol co-treated with dienogest] results in increased expression of F7 protein
|
CTD |
PMID:15288212 |
|
NCBI chr16:83,191,896...83,202,775
Ensembl chr16:83,191,914...83,202,738
|
|
| G
|
Fga
|
fibrinogen alpha chain
|
multiple interactions
|
ISO
|
[Ethinyl Estradiol co-treated with dienogest] results in increased expression of [FGA protein binds to FGB protein binds to FGG protein]
|
CTD |
PMID:15288212 |
|
NCBI chr 2:168,374,120...168,381,523
Ensembl chr 2:170,672,012...170,679,577
|
|
| G
|
Fgb
|
fibrinogen beta chain
|
multiple interactions
|
ISO
|
[Ethinyl Estradiol co-treated with dienogest] results in increased expression of [FGA protein binds to FGB protein binds to FGG protein]
|
CTD |
PMID:15288212 |
|
NCBI chr 2:170,693,966...170,700,875
Ensembl chr 2:170,692,965...170,705,434
|
|
| G
|
Fgg
|
fibrinogen gamma chain
|
multiple interactions
|
ISO
|
[Ethinyl Estradiol co-treated with dienogest] results in increased expression of [FGA protein binds to FGB protein binds to FGG protein]
|
CTD |
PMID:15288212 |
|
NCBI chr 2:170,652,929...170,660,372
Ensembl chr 2:170,652,234...170,661,170
|
|
| G
|
Fshb
|
follicle stimulating hormone subunit beta
|
decreases expression
|
ISO
|
dienogest results in decreased expression of FSHB protein
|
CTD |
PMID:11994349 |
|
NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:114,003,262...114,007,072
|
|
| G
|
Hmgb1
|
high mobility group box 1
|
multiple interactions
|
ISO
|
dienogest inhibits the reaction [[Lipopolysaccharides co-treated with HMGB1 protein] results in increased expression of CCL2 protein]; dienogest inhibits the reaction [[Lipopolysaccharides co-treated with HMGB1 protein] results in increased expression of CXCL8 protein]; dienogest inhibits the reaction [[Lipopolysaccharides co-treated with HMGB1 protein] results in increased expression of IL6 protein]; dienogest inhibits the reaction [[Lipopolysaccharides co-treated with HMGB1 protein] results in increased expression of TLR4 mRNA]
|
CTD |
PMID:22014880 |
|
NCBI chr12:11,009,236...11,015,941
Ensembl chr16:39,039,050...39,041,327 Ensembl chr12:39,039,050...39,041,327
|
|
| G
|
Hsd17b2
|
hydroxysteroid (17-beta) dehydrogenase 2
|
decreases expression
|
ISO
|
dienogest results in decreased expression of HSD17B2 mRNA
|
CTD |
PMID:23183084 |
|
NCBI chr19:45,753,576...45,825,203
Ensembl chr19:62,662,098...62,733,943
|
|
| G
|
Igf1
|
insulin-like growth factor 1
|
multiple interactions
|
ISO
|
[Ethinyl Estradiol co-treated with dienogest] results in decreased expression of IGF1 protein
|
CTD |
PMID:11172797 |
|
NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:24,130,137...24,246,764
|
|
| G
|
Il6
|
interleukin 6
|
multiple interactions
|
ISO
|
dienogest inhibits the reaction [[Lipopolysaccharides co-treated with HMGB1 protein] results in increased expression of IL6 protein]
|
CTD |
PMID:22014880 |
|
NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
|
|
| G
|
Lhb
|
luteinizing hormone subunit beta
|
decreases expression
|
ISO
|
dienogest results in decreased expression of LHB protein
|
CTD |
PMID:11994349 |
|
NCBI chr 1:105,037,457...105,038,446
Ensembl chr 1:105,037,457...105,038,445
|
|
| G
|
Nfkb1
|
nuclear factor kappa B subunit 1
|
multiple interactions affects localization
|
ISO
|
dienogest inhibits the reaction [[Estradiol co-treated with TNF protein] results in increased activity of NFKB1 protein] dienogest affects the localization of NFKB1 protein
|
CTD |
PMID:15866594 PMID:22130322 |
|
NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:226,689,745...226,783,088
|
|
| G
|
Plat
|
plasminogen activator, tissue type
|
multiple interactions
|
ISO
|
[Ethinyl Estradiol co-treated with dienogest] results in decreased expression of PLAT protein
|
CTD |
PMID:15288212 |
|
NCBI chr16:75,943,061...76,022,037
Ensembl chr16:75,943,064...75,967,696
|
|
| G
|
Proc
|
protein C, inactivator of coagulation factors Va and VIIIa
|
multiple interactions
|
ISO
|
[Ethinyl Estradiol co-treated with dienogest] results in increased activity of PROC protein
|
CTD |
PMID:15288212 |
|
NCBI chr18:24,038,596...24,049,061
Ensembl chr18:24,038,597...24,048,964
|
|
| G
|
Pros1
|
protein S
|
multiple interactions
|
ISO
|
[Ethinyl Estradiol co-treated with dienogest] results in decreased expression of PROS1 protein
|
CTD |
PMID:15288212 |
|
NCBI chr11:230,597...311,288
Ensembl chr11:13,676,769...13,757,852
|
|
| G
|
Ptgs2
|
prostaglandin-endoperoxide synthase 2
|
decreases expression
|
ISO
|
dienogest results in decreased expression of PTGS2 mRNA; dienogest results in decreased expression of PTGS2 protein
|
CTD |
PMID:22130322 |
|
NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320
|
|
| G
|
Serpinc1
|
serpin family C member 1
|
multiple interactions
|
ISO
|
[Ethinyl Estradiol co-treated with dienogest] results in decreased activity of SERPINC1 protein
|
CTD |
PMID:15288212 |
|
NCBI chr13:75,790,558...75,804,826
Ensembl chr13:75,790,546...75,817,643
|
|
| G
|
Serpine1
|
serpin family E member 1
|
multiple interactions
|
ISO
|
[Ethinyl Estradiol co-treated with dienogest] results in decreased expression of SERPINE1 protein
|
CTD |
PMID:15288212 |
|
NCBI chr12:25,237,977...25,248,356
Ensembl chr12:25,237,952...25,248,357
|
|
| G
|
Tlr4
|
toll-like receptor 4
|
multiple interactions
|
ISO
|
dienogest inhibits the reaction [[Lipopolysaccharides co-treated with HMGB1 protein] results in increased expression of TLR4 mRNA]
|
CTD |
PMID:22014880 |
|
NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:85,161,192...85,175,007
|
|
| G
|
Tnf
|
tumor necrosis factor
|
multiple interactions
|
ISO
|
dienogest inhibits the reaction [[Estradiol co-treated with TNF protein] results in increased activity of NFKB1 protein]; dienogest inhibits the reaction [[Estradiol co-treated with TNF protein] results in increased expression of CXCL8 mRNA]; dienogest inhibits the reaction [[Estradiol co-treated with TNF protein] results in increased expression of CXCL8 protein]
|
CTD |
PMID:15866594 |
|
NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
|
|
|
|
| G
|
Abcb11
|
ATP binding cassette subfamily B member 11
|
decreases activity
|
ISO
|
drospirenone results in decreased activity of ABCB11 protein
|
CTD |
PMID:23956101 |
|
NCBI chr 3:74,424,620...74,520,646
Ensembl chr 3:74,424,979...74,520,581
|
|
| G
|
Ar
|
androgen receptor
|
multiple interactions affects localization
|
ISO
|
drospirenone binds to and results in increased activity of AR protein drospirenone affects the localization of AR protein
|
CTD |
PMID:28478275 |
|
NCBI chr X:67,135,317...67,304,476
Ensembl chr X:67,135,317...67,304,467
|
|
| G
|
Cyp17a1
|
cytochrome P450, family 17, subfamily a, polypeptide 1
|
multiple interactions
|
ISO
|
[Ethinyl Estradiol co-treated with drospirenone] results in decreased activity of CYP17A1 protein
|
CTD |
PMID:17418832 |
|
NCBI chr 1:255,476,861...255,484,547
Ensembl chr 1:255,476,861...255,482,974
|
|
| G
|
Hsd11b1
|
hydroxysteroid 11-beta dehydrogenase 1
|
multiple interactions
|
ISO
|
drospirenone inhibits the reaction [HSD11B1 protein results in increased reduction of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone]
|
CTD |
PMID:28257955 |
|
NCBI chr13:107,277,526...107,327,462
Ensembl chr13:107,257,239...107,327,432
|
|
| G
|
Hspd1
|
heat shock protein family D (Hsp60) member 1
|
multiple interactions
|
ISO
|
[Ethinyl Estradiol co-treated with drospirenone] results in increased expression of HSPD1 mRNA
|
CTD |
PMID:19631796 |
|
NCBI chr 9:64,073,610...64,084,332
Ensembl chr 9:64,073,611...64,084,037
|
|
| G
|
Nos2
|
nitric oxide synthase 2
|
multiple interactions
|
ISO
|
[Ethinyl Estradiol co-treated with drospirenone] results in decreased expression of NOS2 mRNA
|
CTD |
PMID:19631796 |
|
NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880
|
|
| G
|
Nr3c2
|
nuclear receptor subfamily 3, group C, member 2
|
affects binding
|
EXP
|
drospirenone binds to NR3C2 protein
|
CTD |
PMID:1493716 PMID:14667981 |
|
NCBI chr19:47,619,853...47,964,089
Ensembl chr19:47,619,853...47,964,078
|
|
| G
|
Pgr
|
progesterone receptor
|
affects binding
|
ISO
|
drospirenone binds to PGR protein
|
CTD |
PMID:14667981 |
|
NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:14,354,398...14,413,271
|
|
| G
|
Serpina6
|
serpin family A member 6
|
multiple interactions
|
ISO
|
[Ethinyl Estradiol co-treated with drospirenone] results in increased expression of SERPINA6 protein
|
CTD |
PMID:11245553 |
|
NCBI chr 6:122,780,040...122,790,274
Ensembl chr 6:128,544,831...128,555,139
|
|
| G
|
Shbg
|
sex hormone binding globulin
|
multiple interactions
|
ISO
|
[Ethinyl Estradiol co-treated with drospirenone] results in increased expression of SHBG protein
|
CTD |
PMID:11245553 |
|
NCBI chr10:54,831,716...54,849,162
Ensembl chr10:54,831,718...54,838,760
|
|
|
|
| G
|
Akr1c1
|
aldo-keto reductase family 1, member C1
|
increases expression decreases expression decreases activity increases metabolic processing
|
ISO
|
Dydrogesterone results in increased expression of AKR1C1 mRNA Dydrogesterone results in decreased expression of AKR1C1 mRNA Dydrogesterone results in decreased activity of AKR1C1 protein AKR1C1 protein results in increased metabolism of Dydrogesterone
|
CTD |
PMID:21182831 PMID:23183084 |
|
NCBI chr17:70,720,397...70,747,285
Ensembl chr17:70,720,398...70,747,247
|
|
| G
|
Akr1c2
|
aldo-keto reductase family 1, member C2
|
decreases activity decreases expression
|
ISO
|
Dydrogesterone results in decreased activity of AKR1C2 protein Dydrogesterone results in decreased expression of AKR1C2 mRNA
|
CTD |
PMID:22245609 PMID:23183084 |
|
NCBI chr17:70,669,684...70,717,935
Ensembl chr17:70,669,710...70,685,686
|
|
| G
|
Akr1c3
|
aldo-keto reductase family 1, member C3
|
decreases activity decreases expression
|
ISO
|
Dydrogesterone results in decreased activity of AKR1C3 protein Dydrogesterone results in decreased expression of AKR1C3 mRNA
|
CTD |
PMID:21182831 PMID:23183084 |
|
NCBI chr17:71,020,884...71,037,779
Ensembl chr17:70,970,900...71,048,438
|
|
| G
|
Edn1
|
endothelin 1
|
multiple interactions
|
ISO
|
Dydrogesterone affects the reaction [Estradiol results in decreased expression of EDN1 protein]
|
CTD |
PMID:12385860 |
|
NCBI chr17:22,660,799...22,666,687
Ensembl chr17:22,660,799...22,666,687
|
|
| G
|
Hsd17b2
|
hydroxysteroid (17-beta) dehydrogenase 2
|
decreases expression increases expression
|
ISO
|
Dydrogesterone results in decreased expression of HSD17B2 mRNA Dydrogesterone results in increased expression of HSD17B2 protein
|
CTD |
PMID:23183084 |
|
NCBI chr19:45,753,576...45,825,203
Ensembl chr19:62,662,098...62,733,943
|
|
| G
|
Ifng
|
interferon gamma
|
decreases expression multiple interactions
|
ISO
|
Dydrogesterone results in decreased expression of IFNG protein Mifepristone inhibits the reaction [Dydrogesterone results in decreased expression of IFNG protein]
|
CTD |
PMID:16045524 |
|
NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216
|
|
| G
|
Il10
|
interleukin 10
|
increases expression
|
ISO
|
Dydrogesterone results in increased expression of IL10 protein
|
CTD |
PMID:16389545 |
|
NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580
|
|
| G
|
Il4
|
interleukin 4
|
increases expression multiple interactions
|
ISO
|
Dydrogesterone results in increased expression of IL4 protein Mifepristone inhibits the reaction [Dydrogesterone results in increased expression of IL4 protein]
|
CTD |
PMID:16045524 PMID:16389545 |
|
NCBI chr10:38,272,003...38,277,549
Ensembl chr10:38,272,003...38,277,549
|
|
| G
|
Il6
|
interleukin 6
|
increases expression multiple interactions
|
ISO
|
Dydrogesterone results in increased expression of IL6 protein Mifepristone inhibits the reaction [Dydrogesterone results in increased expression of IL6 protein]
|
CTD |
PMID:16045524 |
|
NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
|
|
| G
|
Pgr
|
progesterone receptor
|
affects activity decreases expression
|
ISO
|
Dydrogesterone affects the activity of PGR protein Dydrogesterone results in decreased expression of PGR mRNA
|
CTD |
PMID:16045524 PMID:23183084 |
|
NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:14,354,398...14,413,271
|
|
| G
|
Pibf1
|
progesterone immunomodulatory binding factor 1
|
affects expression increases expression
|
ISO
|
Dydrogesterone affects the expression of PIBF1 protein Dydrogesterone results in increased expression of PIBF1 protein
|
CTD |
PMID:15760377 PMID:16045524 |
|
NCBI chr15:82,258,243...82,427,546
Ensembl chr15:82,258,468...82,427,548
|
|
| G
|
Srd5a1
|
steroid 5 alpha-reductase 1
|
decreases expression
|
ISO
|
Dydrogesterone results in decreased expression of SRD5A1 mRNA
|
CTD |
PMID:23183084 |
|
NCBI chr 1:35,514,914...35,548,898
Ensembl chr 1:35,514,846...35,548,903
|
|
| G
|
Tacr1
|
tachykinin receptor 1
|
decreases expression
|
ISO
|
Dydrogesterone results in decreased expression of TACR1 protein
|
CTD |
PMID:16389545 |
|
NCBI chr 4:116,478,617...116,647,492
Ensembl chr 4:116,478,617...116,647,492
|
|
| G
|
Tnf
|
tumor necrosis factor
|
decreases expression multiple interactions
|
ISO
|
Dydrogesterone results in decreased expression of TNF protein Mifepristone inhibits the reaction [Dydrogesterone results in decreased expression of TNF protein]
|
CTD |
PMID:16045524 |
|
NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
|
|
|
|
| G
|
Esr1
|
estrogen receptor 1
|
multiple interactions
|
ISO
|
ESR1 protein affects the reaction [Ethisterone results in increased expression of GREB1 mRNA]; ESR1 protein affects the reaction [Ethisterone results in increased expression of SGK1 mRNA]
|
CTD |
PMID:33405908 |
|
NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:43,644,392...43,900,354
|
|
| G
|
Greb1
|
growth regulating estrogen receptor binding 1
|
multiple interactions increases expression
|
ISO
|
ESR1 protein affects the reaction [Ethisterone results in increased expression of GREB1 mRNA]; Fulvestrant inhibits the reaction [Ethisterone results in increased expression of GREB1 mRNA]
|
CTD |
PMID:33405908 |
|
NCBI chr 6:45,169,289...45,321,973
Ensembl chr 6:45,169,289...45,291,126
|
|
| G
|
Mybl1
|
MYB proto-oncogene like 1
|
multiple interactions increases expression
|
ISO
|
Fulvestrant inhibits the reaction [Ethisterone results in increased expression of MYBL1 mRNA]
|
CTD |
PMID:33405908 |
|
NCBI chr 5:14,365,768...14,401,012
Ensembl chr 5:14,365,768...14,399,588
|
|
| G
|
Sgk1
|
serum/glucocorticoid regulated kinase 1
|
multiple interactions increases expression
|
ISO
|
ESR1 protein affects the reaction [Ethisterone results in increased expression of SGK1 mRNA]; Fulvestrant inhibits the reaction [Ethisterone results in increased expression of SGK1 mRNA]
|
CTD |
PMID:33405908 |
|
NCBI chr 1:24,799,391...24,916,886
Ensembl chr 1:24,799,396...24,807,231
|
|
|
|
| G
|
Ar
|
androgen receptor
|
affects localization multiple interactions
|
ISO
|
Ethynodiol Diacetate affects the localization of AR protein Ethynodiol Diacetate binds to and results in increased activity of AR protein
|
CTD |
PMID:28478275 |
|
NCBI chr X:67,135,317...67,304,476
Ensembl chr X:67,135,317...67,304,467
|
|
|
|
| G
|
Cyp3a2
|
cytochrome P450, family 3, subfamily a, polypeptide 2
|
affects metabolic processing
|
ISO
|
CYP3A4 protein affects the metabolism of etonogestrel
|
CTD |
PMID:15963096 |
|
NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857
|
|
| G
|
F2
|
coagulation factor II, thrombin
|
multiple interactions
|
EXP
|
etonogestrel promotes the reaction [F2 protein results in increased expression of F3 mRNA]
|
CTD |
PMID:11733402 |
|
NCBI chr 3:98,051,958...98,065,246
Ensembl chr 3:98,051,960...98,065,246
|
|
| G
|
F2r
|
coagulation factor II (thrombin) receptor
|
multiple interactions increases expression
|
EXP
|
Mifepristone inhibits the reaction [etonogestrel results in increased expression of F2R mRNA]
|
CTD |
PMID:11733402 |
|
NCBI chr 2:26,869,343...26,885,856
Ensembl chr 2:28,604,066...28,620,579
|
|
| G
|
F3
|
coagulation factor III, tissue factor
|
multiple interactions
|
EXP
|
etonogestrel promotes the reaction [F2 protein results in increased expression of F3 mRNA]
|
CTD |
PMID:11733402 |
|
NCBI chr 2:212,511,675...212,523,375
Ensembl chr 2:212,511,680...212,523,369
|
|
| G
|
Pgr
|
progesterone receptor
|
increases expression
|
ISO
|
etonogestrel results in increased expression of PGR protein
|
CTD |
PMID:11041225 |
|
NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:14,354,398...14,413,271
|
|
|
|
| G
|
Akt1
|
AKT serine/threonine kinase 1
|
multiple interactions
|
ISO
|
Fluorometholone inhibits the reaction [Glucose results in decreased phosphorylation of AKT1 protein]
|
CTD |
PMID:35264022 |
|
NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610
|
|
| G
|
Casp3
|
caspase 3
|
multiple interactions
|
ISO
|
Fluorometholone inhibits the reaction [Glucose results in increased activity of CASP3 protein]
|
CTD |
PMID:35264022 |
|
NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
|
|
| G
|
Cdkn1a
|
cyclin-dependent kinase inhibitor 1A
|
multiple interactions
|
ISO
|
Fluorometholone inhibits the reaction [Glucose results in increased expression of CDKN1A protein]
|
CTD |
PMID:35264022 |
|
NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969
|
|
| G
|
F3
|
coagulation factor III, tissue factor
|
multiple interactions
|
ISO
|
Fluorometholone inhibits the reaction [Glucose results in increased expression of F3 mRNA]; Fluorometholone inhibits the reaction [Glucose results in increased expression of F3 protein]
|
CTD |
PMID:35264022 |
|
NCBI chr 2:212,511,675...212,523,375
Ensembl chr 2:212,511,680...212,523,369
|
|
| G
|
Glb1
|
galactosidase, beta 1
|
multiple interactions
|
ISO
|
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Fluorometholone inhibits the reaction [Glucose results in increased activity of GLB1 protein]]; Fluorometholone inhibits the reaction [Glucose results in increased activity of GLB1 protein]
|
CTD |
PMID:35264022 |
|
NCBI chr 8:122,963,718...123,036,326
Ensembl chr 8:122,963,718...123,036,326
|
|
| G
|
Il6
|
interleukin 6
|
multiple interactions
|
ISO
|
Fluorometholone inhibits the reaction [Glucose results in increased expression of IL6 mRNA]; Fluorometholone inhibits the reaction [Glucose results in increased secretion of IL6 protein]
|
CTD |
PMID:35264022 |
|
NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
|
|
| G
|
Rb1
|
RB transcriptional corepressor 1
|
multiple interactions
|
ISO
|
Fluorometholone inhibits the reaction [Glucose results in increased expression of RB1 protein]
|
CTD |
PMID:35264022 |
|
NCBI chr15:54,780,858...54,911,989
Ensembl chr15:54,780,858...54,911,857
|
|
| G
|
Slc22a2
|
solute carrier family 22 member 2
|
multiple interactions
|
ISO
|
Fluorometholone inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium]
|
CTD |
PMID:21599003 |
|
NCBI chr 1:50,668,817...50,711,019
Ensembl chr 1:50,668,817...50,711,019
|
|
| G
|
Tert
|
telomerase reverse transcriptase
|
multiple interactions
|
ISO
|
Fluorometholone inhibits the reaction [Glucose results in decreased activity of TERT protein]
|
CTD |
PMID:35264022 |
|
NCBI chr 1:29,637,213...29,659,561
Ensembl chr 1:31,466,056...31,488,111
|
|
| G
|
Tnf
|
tumor necrosis factor
|
multiple interactions
|
ISO
|
Fluorometholone inhibits the reaction [Glucose results in increased expression of TNF mRNA]; Fluorometholone inhibits the reaction [Glucose results in increased secretion of TNF protein]
|
CTD |
PMID:35264022 |
|
NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
|
|
| G
|
Tp53
|
tumor protein p53
|
multiple interactions
|
ISO
|
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Fluorometholone inhibits the reaction [Glucose results in increased expression of TP53 protein]]; Fluorometholone inhibits the reaction [Glucose results in increased expression of TP53 protein]
|
CTD |
PMID:35264022 |
|
NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299
|
|
| G
|
Vegfa
|
vascular endothelial growth factor A
|
multiple interactions
|
ISO
|
Fluorometholone inhibits the reaction [Glucose results in increased expression of VEGFA mRNA]; Fluorometholone inhibits the reaction [Glucose results in increased expression of VEGFA protein]
|
CTD |
PMID:35264022 |
|
NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194
|
|
|
|
| G
|
Abcb1a
|
ATP binding cassette subfamily B member 1A
|
increases expression
|
ISO
|
Levonorgestrel results in increased expression of ABCB1 mRNA
|
CTD |
PMID:15290871 |
|
NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:26,312,409...26,397,135
|
|
| G
|
Abhd5
|
abhydrolase domain containing 5, lysophosphatidic acid acyltransferase
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of ABHD5 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr 8:130,877,834...130,903,947
Ensembl chr 8:130,877,703...130,903,947
|
|
| G
|
Ace2
|
angiotensin converting enzyme 2
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of ACE2 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr X:30,293,597...30,340,961
Ensembl chr X:33,925,458...33,971,596
|
|
| G
|
Adgrf5
|
adhesion G protein-coupled receptor F5
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of ADGRF5 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr 9:25,014,861...25,128,045
Ensembl chr 9:25,018,277...25,121,237
|
|
| G
|
Afg1l
|
AFG1 like ATPase
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of AFG1L mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr20:45,798,344...45,967,997
Ensembl chr20:47,380,583...47,550,126
|
|
| G
|
Agt
|
angiotensinogen
|
multiple interactions
|
ISO
|
[Ethinyl Estradiol co-treated with Levonorgestrel] results in increased expression of AGT protein
|
CTD |
PMID:17519148 |
|
NCBI chr19:69,426,540...69,447,017
Ensembl chr19:69,421,638...69,446,944
|
|
| G
|
Ahctf1
|
AT hook containing transcription factor 1
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of AHCTF1 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr13:91,481,936...91,536,391
Ensembl chr13:94,014,469...94,068,058
|
|
| G
|
Akr1c3
|
aldo-keto reductase family 1, member C3
|
decreases activity
|
ISO
|
Levonorgestrel results in decreased activity of AKR1C3 protein
|
CTD |
PMID:21182831 |
|
NCBI chr17:71,020,884...71,037,779
Ensembl chr17:70,970,900...71,048,438
|
|
| G
|
Alms1
|
ALMS1, centrosome and basal body associated protein
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of ALMS1 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr 4:119,683,085...119,783,471
Ensembl chr 4:119,683,076...119,783,471
|
|
| G
|
Alpk2
|
alpha-kinase 2
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of ALPK2 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr18:61,045,717...61,161,703
Ensembl chr18:61,045,380...61,175,985
|
|
| G
|
Alpl
|
alkaline phosphatase, biomineralization associated
|
multiple interactions
|
ISO
|
VDR gene polymorphism affects the reaction [[Ethinyl Estradiol co-treated with Levonorgestrel] affects the expression of ALPL protein]
|
CTD |
PMID:12521655 |
|
NCBI chr 5:155,234,770...155,289,785
Ensembl chr 5:155,234,775...155,254,167
|
|
| G
|
Ammecr1
|
AMMECR nuclear protein 1
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of AMMECR1 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr X:111,262,792...111,368,099
Ensembl chr X:111,262,792...111,368,099
|
|
| G
|
Ankdd1a
|
ankyrin repeat and death domain containing 1A
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of ANKDD1A mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr 8:74,912,707...74,938,870
Ensembl chr 8:74,916,011...74,937,863
|
|
| G
|
Api5
|
apoptosis inhibitor 5
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of API5 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr 3:100,833,417...100,858,580
Ensembl chr 3:100,833,417...100,858,580
|
|
| G
|
Apob
|
apolipoprotein B
|
multiple interactions
|
ISO
|
[Ethinyl Estradiol co-treated with Levonorgestrel] results in increased expression of APOB protein
|
CTD |
PMID:15769986 |
|
NCBI chr 6:36,563,704...36,603,300
Ensembl chr 6:36,563,704...36,611,814
|
|
| G
|
Ar
|
androgen receptor
|
affects binding multiple interactions
|
EXP ISO
|
Levonorgestrel binds to AR protein Levonorgestrel binds to and results in increased activity of AR protein
|
CTD |
PMID:14565775 PMID:19833195 PMID:20438827 |
|
NCBI chr X:67,135,317...67,304,476
Ensembl chr X:67,135,317...67,304,467
|
|
| G
|
Arhgap23
|
Rho GTPase activating protein 23
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of ARHGAP23 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr10:82,437,578...82,496,846
Ensembl chr10:82,890,853...82,993,228
|
|
| G
|
Arl9
|
ARF like GTPase 9
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of ARL9 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr14:31,511,845...31,521,038
Ensembl chr14:31,511,330...31,520,988
|
|
| G
|
Asap1
|
ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of ASAP1 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr 7:95,786,130...96,093,111
Ensembl chr 7:97,675,354...97,982,024
|
|
| G
|
Azgp1
|
alpha-2-glycoprotein 1, zinc-binding
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of AZGP1 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr12:22,044,685...22,051,248
Ensembl chr12:22,044,751...22,053,020
|
|
| G
|
B4galt5
|
beta-1,4-galactosyltransferase 5
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of B4GALT5 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr 3:176,437,073...176,453,001
Ensembl chr 3:176,437,073...176,488,978
|
|
| G
|
Bbx
|
BBX high mobility group box domain containing
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of BBX mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr11:63,850,034...64,097,700
Ensembl chr11:63,850,018...64,093,265
|
|
| G
|
Bcl2
|
BCL2, apoptosis regulator
|
decreases expression
|
ISO
|
Levonorgestrel results in decreased expression of BCL2 protein
|
CTD |
PMID:16019350 |
|
NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900
|
|
| G
|
Bcl2l14
|
Bcl2-like 14
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of BCL2L14 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr 4:168,948,919...168,989,450
Ensembl chr 4:168,948,946...168,990,079
|
|
| G
|
Bglap
|
bone gamma-carboxyglutamate protein
|
multiple interactions
|
ISO
|
VDR gene polymorphism affects the reaction [[Ethinyl Estradiol co-treated with Levonorgestrel] affects the expression of BGLAP protein]
|
CTD |
PMID:12521655 |
|
NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:176,136,341...176,137,318
|
|
| G
|
Btbd3
|
BTB domain containing 3
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of BTBD3 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr 3:125,591,427...125,621,660
Ensembl chr 3:146,044,096...146,074,635
|
|
| G
|
C3
|
complement C3
|
multiple interactions
|
EXP
|
Levonorgestrel inhibits the reaction [Ethinyl Estradiol results in increased expression of C3 mRNA]
|
CTD |
PMID:11566438 |
|
NCBI chr 9:2,174,412...2,201,339
Ensembl chr 9:2,174,412...2,201,339
|
|
| G
|
C4bpb
|
complement component 4 binding protein, beta
|
multiple interactions
|
ISO
|
[Ethinyl Estradiol co-treated with Levonorgestrel] results in decreased expression of C4BPB protein; F5 gene polymorphism inhibits the reaction [[Ethinyl Estradiol co-treated with Levonorgestrel] results in decreased expression of C4BPB protein]
|
CTD |
PMID:14551147 |
|
NCBI chr13:44,673,064...44,683,781
Ensembl chr13:44,673,065...44,683,793
|
|
| G
|
Cat
|
catalase
|
multiple interactions
|
ISO
|
[Ethinyl Estradiol co-treated with Levonorgestrel] results in decreased activity of CAT protein
|
CTD |
PMID:17541152 |
|
NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526
|
|
| G
|
Ccn3
|
cellular communication network factor 3
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of CCN3 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr 7:87,983,788...87,990,810
Ensembl chr 7:87,982,216...87,994,581
|
|
| G
|
Cd86
|
CD86 molecule
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of CD86 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr11:77,647,565...77,706,178
Ensembl chr11:77,647,600...77,725,361
|
|
| G
|
Cdc25c
|
cell division cycle 25C
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of CDC25C mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr18:26,335,156...26,356,199
Ensembl chr18:26,609,959...26,630,292
|
|
| G
|
Cdc42bpb
|
CDC42 binding protein kinase beta
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of CDC42BPB mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr 6:130,333,712...130,416,631
Ensembl chr 6:136,154,905...136,237,570
|
|
| G
|
Cdkn2d
|
cyclin dependent kinase inhibitor 2D
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of CDKN2D mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr 8:28,108,036...28,110,809
Ensembl chr 8:28,108,044...28,110,809
|
|
| G
|
Cep170b
|
centrosomal protein 170B
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of CEP170B mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr 6:131,780,935...131,806,658
Ensembl chr 6:137,602,707...137,627,750
|
|
| G
|
Cfap65
|
cilia and flagella associated protein 65
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of CFAP65 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr 9:76,459,211...76,494,199
Ensembl chr 9:83,907,276...83,942,714
|
|
| G
|
Chek2
|
checkpoint kinase 2
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of CHEK2 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr12:45,788,823...45,821,382
Ensembl chr12:51,449,140...51,480,667
|
|
| G
|
Cimap1a
|
ciliary microtubule associated protein 1A
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of CIMAP1A mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr 1:205,355,601...205,358,882
Ensembl chr 1:205,355,675...205,358,882
|
|
| G
|
Col1a1
|
collagen type I alpha 1 chain
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of COL1A1 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr10:80,380,458...80,397,461
Ensembl chr10:80,380,453...80,397,460
|
|
| G
|
Col22a1
|
collagen type XXII alpha 1 chain
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of COL22A1 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr 7:105,619,776...105,857,246
Ensembl chr 7:105,619,757...105,856,960
|
|
| G
|
Cpeb3
|
cytoplasmic polyadenylation element binding protein 3
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of CPEB3 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr 1:244,161,690...244,343,765
Ensembl chr 1:244,161,690...244,343,561
|
|
| G
|
Cpxcr1
|
CPX chromosome region, candidate 1
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of CPXCR1 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr X:81,756,909...81,794,661
|
|
| G
|
Crlf3
|
cytokine receptor-like factor 3
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of CRLF3 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr10:65,024,228...65,060,746
Ensembl chr10:65,521,492...65,558,804
|
|
| G
|
Crp
|
C-reactive protein
|
multiple interactions
|
ISO
|
[Ethinyl Estradiol co-treated with Levonorgestrel] results in increased expression of CRP protein
|
CTD |
PMID:15769986 |
|
NCBI chr13:87,694,062...87,695,978
Ensembl chr13:87,657,317...87,707,514
|
|
| G
|
Csmd1
|
CUB and Sushi multiple domains 1
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of CSMD1 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr16:78,920,549...80,520,710
Ensembl chr16:78,921,002...80,519,944
|
|
| G
|
Csnk1a1
|
casein kinase 1, alpha 1
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of CSNK1A1 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr18:57,285,156...57,320,540
Ensembl chr18:57,287,412...57,320,538
|
|
| G
|
Cxcl10
|
C-X-C motif chemokine ligand 10
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of CXCL10 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr14:15,989,066...15,991,263
Ensembl chr14:15,989,018...15,991,261
|
|
| G
|
Cyp17a1
|
cytochrome P450, family 17, subfamily a, polypeptide 1
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of CYP17A1 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr 1:255,476,861...255,484,547
Ensembl chr 1:255,476,861...255,482,974
|
|
| G
|
Dap3
|
death associated protein 3
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of DAP3 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr 2:174,319,341...174,347,489
Ensembl chr 2:176,617,155...176,644,270
|
|
| G
|
Dcn
|
decorin
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of DCN mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr 7:34,167,973...34,208,004
Ensembl chr 7:34,163,011...34,218,926
|
|
| G
|
Ddhd1
|
DDHD domain containing 1
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of DDHD1 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr15:18,824,389...18,891,036
Ensembl chr15:21,303,826...21,370,608
|
|
| G
|
Dlgap2
|
DLG associated protein 2
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of DLGAP2 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr16:81,489,059...82,198,693
Ensembl chr16:81,494,649...82,198,684
|
|
| G
|
Dnase1l3
|
deoxyribonuclease 1L3
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of DNASE1L3 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr15:19,351,683...19,378,536
Ensembl chr15:19,352,493...19,378,531
|
|
| G
|
Dock8
|
dedicator of cytokinesis 8
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of DOCK8 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr 1:232,075,468...232,268,830
Ensembl chr 1:232,075,588...232,268,833
|
|
| G
|
Dok5
|
docking protein 5
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of DOK5 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr 3:179,934,419...180,071,334
Ensembl chr 3:179,934,552...180,071,333
|
|
| G
|
Dsg1
|
desmoglein 1
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of DSG1 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr18:11,948,098...11,980,455
Ensembl chr18:11,949,488...11,980,451
|
|
| G
|
Elovl5
|
ELOVL fatty acid elongase 5
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of ELOVL5 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr 8:87,671,164...87,737,618
Ensembl chr 8:87,671,159...87,737,616
|
|
| G
|
Eprs1
|
glutamyl-prolyl-tRNA synthetase 1
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of EPRS1 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr13:99,431,955...99,503,510
Ensembl chr13:99,433,130...99,503,509
|
|
| G
|
Esr1
|
estrogen receptor 1
|
multiple interactions
|
ISO
|
Levonorgestrel binds to and results in increased activity of ESR1 protein
|
CTD |
PMID:33049310 |
|
NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:43,644,392...43,900,354
|
|
| G
|
Etnk1
|
ethanolamine kinase 1
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of ETNK1 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr 4:176,126,056...176,170,325
Ensembl chr 4:177,856,960...177,924,721
|
|
| G
|
Evi2b
|
ecotropic viral integration site 2B
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of EVI2B mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr10:64,970,659...64,972,277
Ensembl chr10:64,964,719...64,979,417
|
|
| G
|
F5
|
coagulation factor V
|
multiple interactions
|
ISO
|
F5 gene polymorphism inhibits the reaction [[Ethinyl Estradiol co-treated with Levonorgestrel] results in decreased expression of C4BPB protein]
|
CTD |
PMID:14551147 |
|
NCBI chr13:79,046,657...79,116,247
Ensembl chr13:79,046,448...79,116,247
|
|
| G
|
F7
|
coagulation factor VII
|
multiple interactions
|
ISO
|
[Ethinyl Estradiol co-treated with Levonorgestrel] results in decreased expression of F7 protein; [Ethinyl Estradiol co-treated with Levonorgestrel] results in increased expression of F7 protein
|
CTD |
PMID:12618251 PMID:15157790 |
|
NCBI chr16:83,191,896...83,202,775
Ensembl chr16:83,191,914...83,202,738
|
|
| G
|
F8
|
coagulation factor VIII
|
multiple interactions
|
ISO
|
[Ethinyl Estradiol co-treated with Levonorgestrel] results in increased expression of F8 protein
|
CTD |
PMID:12618251 |
|
NCBI chr18:140,848...172,330
Ensembl chr18:155,309...186,683
|
|
| G
|
Fam20a
|
FAM20A, golgi associated secretory pathway pseudokinase
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of FAM20A mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr10:95,136,799...95,197,176
Ensembl chr10:95,142,458...95,197,053
|
|
| G
|
Far2
|
fatty acyl CoA reductase 2
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of FAR2 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr 4:180,973,968...181,087,862
Ensembl chr 4:182,705,381...182,825,279
|
|
| G
|
Fcrl5
|
Fc receptor-like 5
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of FCRL5 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr 2:172,881,763...172,912,912
Ensembl chr 2:175,179,690...175,211,039
|
|
| G
|
Fermt2
|
FERM domain containing kindlin 2
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of FERMT2 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr15:18,682,927...18,751,959
Ensembl chr15:21,162,605...21,258,115
|
|
| G
|
Fga
|
fibrinogen alpha chain
|
multiple interactions
|
ISO
|
[Ethinyl Estradiol co-treated with Levonorgestrel] results in increased expression of [FGA protein binds to FGB protein binds to FGG protein]
|
CTD |
PMID:12618251 PMID:15288212 |
|
NCBI chr 2:168,374,120...168,381,523
Ensembl chr 2:170,672,012...170,679,577
|
|
| G
|
Fgb
|
fibrinogen beta chain
|
multiple interactions
|
ISO
|
[Ethinyl Estradiol co-treated with Levonorgestrel] results in increased expression of [FGA protein binds to FGB protein binds to FGG protein]
|
CTD |
PMID:12618251 PMID:15288212 |
|
NCBI chr 2:170,693,966...170,700,875
Ensembl chr 2:170,692,965...170,705,434
|
|
| G
|
Fgg
|
fibrinogen gamma chain
|
multiple interactions
|
ISO
|
[Ethinyl Estradiol co-treated with Levonorgestrel] results in increased expression of [FGA protein binds to FGB protein binds to FGG protein]
|
CTD |
PMID:12618251 PMID:15288212 |
|
NCBI chr 2:170,652,929...170,660,372
Ensembl chr 2:170,652,234...170,661,170
|
|
| G
|
Fkbp6
|
FKBP prolyl isomerase family member 6
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of FKBP6 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr12:21,318,251...21,390,350
Ensembl chr12:26,947,384...27,026,913
|
|
| G
|
Fmnl3
|
formin-like 3
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of FMNL3 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr 7:130,454,270...130,505,626
Ensembl chr 7:132,333,130...132,384,483
|
|
| G
|
Fnbp1
|
formin binding protein 1
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of FNBP1 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr 3:14,309,067...14,424,378
Ensembl chr 3:34,706,814...34,822,117
|
|
| G
|
Fshb
|
follicle stimulating hormone subunit beta
|
multiple interactions
|
ISO
|
[Ethinyl Estradiol co-treated with Levonorgestrel] results in decreased expression of FSHB protein; Avosentan affects the reaction [[Ethinyl Estradiol co-treated with Levonorgestrel] affects the expression of FSHB protein]
|
CTD |
PMID:16291413 PMID:17190377 |
|
NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:114,003,262...114,007,072
|
|
| G
|
Gabrg2
|
gamma-aminobutyric acid type A receptor subunit gamma 2
|
increases expression
|
EXP
|
Levonorgestrel results in increased expression of GABRG2 protein
|
CTD |
PMID:22634062 |
|
NCBI chr10:26,876,926...26,965,523
Ensembl chr10:26,876,926...26,965,523
|
|
| G
|
Gas6
|
growth arrest specific 6
|
multiple interactions
|
ISO
|
[Ethinyl Estradiol co-treated with Levonorgestrel] results in decreased expression of GAS6 protein
|
CTD |
PMID:17717130 |
|
NCBI chr16:76,045,430...76,075,904
Ensembl chr16:82,747,345...82,778,088
|
|
| G
|
Gdf10
|
growth differentiation factor 10
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of GDF10 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr16:9,237,182...9,250,537
Ensembl chr16:9,243,317...9,256,794
|
|
| G
|
Gh1
|
growth hormone 1
|
multiple interactions
|
ISO
|
[Ethinyl Estradiol co-treated with Levonorgestrel] results in increased expression of GH1 protein
|
CTD |
PMID:11172797 |
|
NCBI chr10:91,727,883...91,729,860
Ensembl chr10:91,727,884...91,729,859
|
|
| G
|
Glyr1
|
glyoxylate reductase 1 homolog
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of GLYR1 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr10:10,532,036...10,567,639
Ensembl chr10:11,038,568...11,074,090
|
|
| G
|
Gpr135
|
G protein-coupled receptor 135
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of GPR135 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr 6:96,363,466...96,366,594
Ensembl chr 6:96,362,867...96,382,988
|
|
| G
|
Greb1
|
growth regulating estrogen receptor binding 1
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of GREB1 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr 6:45,169,289...45,321,973
Ensembl chr 6:45,169,289...45,291,126
|
|
| G
|
Hmmr
|
hyaluronan-mediated motility receptor
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of HMMR mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr10:25,635,249...25,665,389
Ensembl chr10:25,635,915...25,665,390
|
|
| G
|
Hoxc6
|
homeo box C6
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of HOXC6 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr 7:134,138,017...134,148,899
Ensembl chr 7:136,024,961...136,027,365
|
|
| G
|
Htr7
|
5-hydroxytryptamine receptor 7
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of HTR7 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr 1:233,636,442...233,761,063
Ensembl chr 1:243,049,081...243,173,230
|
|
| G
|
Ice2
|
interactor of little elongation complex ELL subunit 2
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of ICE2 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr 8:70,043,419...70,085,217
Ensembl chr 8:78,924,421...78,966,200
|
|
| G
|
Igf1
|
insulin-like growth factor 1
|
multiple interactions
|
ISO
|
[Ethinyl Estradiol co-treated with Levonorgestrel] results in decreased expression of IGF1 protein
|
CTD |
PMID:11172797 |
|
NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:24,130,137...24,246,764
|
|
| G
|
Igfbp3
|
insulin-like growth factor binding protein 3
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of IGFBP3 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr14:86,270,208...86,277,944
Ensembl chr14:86,270,208...86,277,944
|
|
| G
|
Igsf1
|
immunoglobulin superfamily, member 1
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of IGSF1 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr X:129,069,891...129,085,331
Ensembl chr X:133,947,429...133,962,962
|
|
| G
|
Inha
|
inhibin subunit alpha
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of INHA mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr 9:76,994,465...76,997,366
Ensembl chr 9:84,443,109...84,446,009
|
|
| G
|
Insl3
|
insulin-like 3
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of INSL3 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr16:18,432,668...18,434,539
|
|
| G
|
Insl6
|
insulin-like 6
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of INSL6 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr 1:236,483,530...236,487,065
Ensembl chr 1:236,483,530...236,487,065
|
|
| G
|
Kbtbd7
|
kelch repeat and BTB domain containing 7
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of KBTBD7 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr15:61,215,957...61,220,536
Ensembl chr15:61,215,396...61,223,671
|
|
| G
|
Kcnh7
|
potassium voltage-gated channel subfamily H member 7
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of KCNH7 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr 3:47,329,338...47,822,122
Ensembl chr 3:67,747,063...68,230,741
|
|
| G
|
Kdsr
|
3-ketodihydrosphingosine reductase
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of KDSR mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr13:23,374,101...23,408,779
Ensembl chr13:23,376,779...23,408,897
|
|
| G
|
Klhl28
|
kelch-like family member 28
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of KLHL28 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr 6:88,723,624...88,755,072
Ensembl chr 6:88,727,205...88,752,457
|
|
| G
|
Klhl4
|
kelch-like family member 4
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of KLHL4 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr X:83,626,047...83,916,328
Ensembl chr X:83,819,076...83,916,328
|
|
| G
|
Ldlr
|
low density lipoprotein receptor
|
affects expression multiple interactions
|
ISO
|
Levonorgestrel affects the expression of LDLR protein [Levonorgestrel co-treated with Ethinyl Estradiol] results in decreased expression of LDLR protein
|
CTD |
PMID:17900441 |
|
NCBI chr 8:28,546,191...28,569,075
Ensembl chr 8:28,546,146...28,570,675
|
|
| G
|
Lhb
|
luteinizing hormone subunit beta
|
multiple interactions decreases secretion
|
ISO
|
[Ethinyl Estradiol co-treated with Levonorgestrel] results in decreased expression of LHB protein; Avosentan affects the reaction [[Ethinyl Estradiol co-treated with Levonorgestrel] affects the expression of LHB protein] Levonorgestrel results in decreased secretion of LHB protein
|
CTD |
PMID:16291413 PMID:17190377 PMID:20599585 |
|
NCBI chr 1:105,037,457...105,038,446
Ensembl chr 1:105,037,457...105,038,445
|
|
| G
|
Limd1
|
LIM domain containing 1
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of LIMD1 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr 8:123,121,363...123,168,476
Ensembl chr 8:131,999,770...132,045,922
|
|
| G
|
Lmntd1
|
lamin tail domain containing 1
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of LMNTD1 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr 4:180,085,128...180,319,362
Ensembl chr 4:180,085,134...180,329,707
|
|
| G
|
Lrig2
|
leucine-rich repeats and immunoglobulin-like domains 2
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of LRIG2 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr 2:191,947,322...192,012,996
Ensembl chr 2:194,638,182...194,700,940
|
|
| G
|
Man2a1
|
mannosidase, alpha, class 2A, member 1
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of MAN2A1 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr 9:104,252,001...104,408,349
Ensembl chr 9:111,698,913...111,867,850
|
|
| G
|
Mbnl1
|
muscleblind-like splicing regulator 1
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of MBNL1 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr 2:144,639,819...144,814,395
Ensembl chr 2:146,789,596...146,964,134
|
|
| G
|
Mep1b
|
meprin A subunit beta
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of MEP1B mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr18:12,641,041...12,667,759
Ensembl chr18:12,641,041...12,667,755
|
|
| G
|
Midn
|
midnolin
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of MIDN mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr 7:10,198,761...10,210,563
Ensembl chr 7:10,200,306...10,207,203
|
|
| G
|
Mki67
|
marker of proliferation Ki-67
|
decreases expression
|
ISO
|
Levonorgestrel results in decreased expression of MKI67 protein
|
CTD |
PMID:16019350 |
|
NCBI chr 1:199,926,150...199,952,847
Ensembl chr 1:199,926,150...199,952,593
|
|
| G
|
Mro
|
maestro
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of MRO mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr18:67,450,186...67,467,593
Ensembl chr18:69,725,798...69,743,031
|
|
| G
|
Mrps6
|
mitochondrial ribosomal protein S6
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of MRPS6 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr11:44,778,667...44,834,420
Ensembl chr11:44,781,554...44,834,962
|
|
| G
|
Mtss1
|
MTSS I-BAR domain containing 1
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of MTSS1 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr 7:92,378,228...92,517,444
Ensembl chr 7:92,378,238...92,517,303
|
|
| G
|
Mysm1
|
myb-like, SWIRM and MPN domains 1
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of MYSM1 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr 5:109,761,345...109,826,652
Ensembl chr 5:114,889,269...114,942,385
|
|
| G
|
Nacc2
|
NACC family member 2
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of NACC2 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr 3:8,879,952...8,946,660
Ensembl chr 3:29,281,190...29,344,840
|
|
| G
|
Ndfip1
|
Nedd4 family interacting protein 1
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of NDFIP1 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr18:30,516,931...30,567,199
Ensembl chr18:30,516,981...30,568,471
|
|
| G
|
Nexn
|
nexilin (F actin binding protein)
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of NEXN mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr 2:241,186,783...241,218,315
Ensembl chr 2:243,846,433...243,887,114
|
|
| G
|
Nid1
|
nidogen 1
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of NID1 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr17:93,069,013...93,142,416
Ensembl chr17:93,069,278...93,142,386
|
|
| G
|
Nr1i2
|
nuclear receptor subfamily 1, group I, member 2
|
multiple interactions
|
ISO
|
Levonorgestrel binds to and results in increased activity of NR1I2 protein
|
CTD |
PMID:33049310 |
|
NCBI chr11:75,965,717...76,006,733
Ensembl chr11:75,965,632...76,002,380
|
|
| G
|
Nsg1
|
neuronal vesicle trafficking associated 1
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of NSG1 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr14:76,861,079...76,882,822
Ensembl chr14:76,860,746...76,883,390
|
|
| G
|
Olfml3
|
olfactomedin-like 3
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of OLFML3 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr 2:191,244,221...191,247,050
Ensembl chr 2:193,932,665...193,935,494
|
|
| G
|
Opn5
|
opsin 5
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of OPN5 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr 9:18,368,393...18,416,098
Ensembl chr 9:25,865,610...25,913,315
|
|
| G
|
Or10j2
|
olfactory receptor family 10 subfamily J member 2
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of OR10J1 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr13:85,723,300...85,724,290
Ensembl chr13:88,255,644...88,256,634
|
|
| G
|
Osbpl10
|
oxysterol binding protein-like 10
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of OSBPL10 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr 8:114,661,050...114,918,664
Ensembl chr 8:123,539,235...123,796,822
|
|
| G
|
Pak3
|
p21 (RAC1) activated kinase 3
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of PAK3 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr X:111,912,967...112,171,037
Ensembl chr X:111,913,059...112,165,035
|
|
| G
|
Pappa
|
pappalysin
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of PAPPA mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr 5:83,513,358...83,751,364
Ensembl chr 5:83,513,358...83,751,361
|
|
| G
|
Pard6b
|
par-6 family cell polarity regulator beta
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of PARD6B mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr 3:156,790,540...156,811,620
Ensembl chr 3:177,209,258...177,230,510
|
|
| G
|
Pcdh7
|
protocadherin 7
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of PCDH7 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr14:56,684,817...57,114,976
Ensembl chr14:56,687,725...57,112,665
|
|
| G
|
Pde1c
|
phosphodiesterase 1C
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of PDE1C mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr 4:85,300,858...85,777,948
Ensembl chr 4:86,626,282...87,193,259
|
|
| G
|
Pgr
|
progesterone receptor
|
multiple interactions
|
ISO
|
Levonorgestrel binds to and results in increased activity of PGR protein
|
CTD |
PMID:20599585 |
|
NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:14,354,398...14,413,271
|
|
| G
|
Pkp4
|
plakophilin 4
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of PKP4 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr 3:43,632,364...43,835,834
Ensembl chr 3:64,141,771...64,244,586
|
|
| G
|
Plagl1
|
PLAG1 like zinc finger 1
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of PLAGL1 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr 1:9,297,066...9,337,394
Ensembl chr 1:9,330,204...9,337,394
|
|
| G
|
Plat
|
plasminogen activator, tissue type
|
multiple interactions
|
ISO
|
[Ethinyl Estradiol co-treated with Levonorgestrel] results in decreased expression of PLAT protein; [Ethinyl Estradiol co-treated with Levonorgestrel] results in increased activity of PLAT protein
|
CTD |
PMID:12618251 PMID:15157790 PMID:15288212 |
|
NCBI chr16:75,943,061...76,022,037
Ensembl chr16:75,943,064...75,967,696
|
|
| G
|
Plg
|
plasminogen
|
multiple interactions
|
ISO
|
[Ethinyl Estradiol co-treated with Levonorgestrel] results in increased expression of PLG protein
|
CTD |
PMID:12618251 PMID:15157790 |
|
NCBI chr 1:50,872,927...50,915,406
Ensembl chr 1:50,872,926...50,917,320
|
|
| G
|
Poglut1
|
protein O-glucosyltransferase 1
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of POGLUT1 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr11:62,198,600...62,226,446
Ensembl chr11:75,703,833...75,733,519
|
|
| G
|
Pon1
|
paraoxonase 1
|
multiple interactions
|
ISO
|
[Ethinyl Estradiol co-treated with Levonorgestrel] affects the activity of PON1 protein
|
CTD |
PMID:17541152 |
|
NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:34,261,289...34,287,924
|
|
| G
|
Ppp2r2c
|
protein phosphatase 2, regulatory subunit B, gamma
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of PPP2R2C mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr14:73,846,547...73,931,489
Ensembl chr14:78,071,274...78,156,212
|
|
| G
|
Prkab1
|
protein kinase AMP-activated non-catalytic subunit beta 1
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of PRKAB1 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr12:46,248,971...46,259,487
Ensembl chr12:46,249,010...46,259,482
|
|
| G
|
Proc
|
protein C, inactivator of coagulation factors Va and VIIIa
|
multiple interactions
|
ISO
|
[Ethinyl Estradiol co-treated with Levonorgestrel] results in increased activity of PROC protein; [Ethinyl Estradiol co-treated with Levonorgestrel] results in increased expression of PROC protein
|
CTD |
PMID:12618251 PMID:14551147 PMID:15288212 |
|
NCBI chr18:24,038,596...24,049,061
Ensembl chr18:24,038,597...24,048,964
|
|
| G
|
Pros1
|
protein S
|
multiple interactions
|
ISO
|
[Ethinyl Estradiol co-treated with Levonorgestrel] results in decreased activity of PROS1 protein; [Ethinyl Estradiol co-treated with Levonorgestrel] results in decreased expression of PROS1 protein
|
CTD |
PMID:12618251 PMID:14551147 |
|
NCBI chr11:230,597...311,288
Ensembl chr11:13,676,769...13,757,852
|
|
| G
|
Ptbp2
|
polypyrimidine tract binding protein 2
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of PTBP2 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr 2:210,497,610...210,558,497
Ensembl chr 2:210,497,706...210,558,291
|
|
| G
|
Ptger2
|
prostaglandin E receptor 2
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of PTGER2 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr15:20,694,765...20,708,475
Ensembl chr15:20,696,013...20,708,950
|
|
| G
|
Ptges
|
prostaglandin E synthase
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of PTGES mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr 3:34,575,643...34,586,987
Ensembl chr 3:34,575,639...34,586,995
|
|
| G
|
Rab11fip3
|
RAB11 family interacting protein 3
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of RAB11FIP3 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr10:15,507,151...15,591,173
Ensembl chr10:15,507,151...15,591,173
|
|
| G
|
Rab1a
|
RAB1A, member RAS oncogene family
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of RAB1A mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr14:94,422,219...94,448,799
Ensembl chr14:98,623,635...98,661,582
|
|
| G
|
Rapgef6
|
Rap guanine nucleotide exchange factor 6
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of RAPGEF6 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr10:38,655,854...38,824,227
Ensembl chr10:39,156,620...39,324,946
|
|
| G
|
Recql
|
RecQ like helicase
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of RECQL mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr 4:175,308,337...175,332,965
Ensembl chr 4:177,035,128...177,063,838
|
|
| G
|
Rftn2
|
raftlin family member 2
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of RFTN2 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr 9:64,146,062...64,202,342
Ensembl chr 9:64,124,865...64,215,186
|
|
| G
|
Rln1
|
relaxin 1
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of RLN1 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr 1:227,079,960...227,082,960
Ensembl chr 1:236,493,536...236,496,440
|
|
| G
|
Rnf216
|
ring finger protein 216
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of RNF216 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr12:16,568,327...16,689,868
Ensembl chr12:16,568,347...16,690,989
|
|
| G
|
Rnft1
|
ring finger protein, transmembrane 1
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of RNFT1 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr10:71,807,403...71,821,132
Ensembl chr10:71,807,456...71,821,141
|
|
| G
|
RT1-Bb
|
RT1 class II, locus Bb
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of HLA-DQB1 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr20:4,598,475...4,604,118
Ensembl chr20:4,598,475...4,604,118
|
|
| G
|
Saraf
|
store-operated calcium entry-associated regulatory factor
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of SARAF mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr16:64,720,404...64,738,653
Ensembl chr16:64,720,418...64,738,653
|
|
| G
|
Scaf4
|
SR-related CTD-associated factor 4
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of SCAF4 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr11:29,460,479...29,521,153
Ensembl chr11:42,951,254...43,007,293
|
|
| G
|
Senp1
|
SUMO specific peptidase 1
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of SENP1 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr 7:131,042,237...131,105,826
Ensembl chr 7:131,044,818...131,100,851
|
|
| G
|
Serpina5
|
serpin family A member 5
|
multiple interactions
|
ISO
|
[Ethinyl Estradiol co-treated with Levonorgestrel] results in increased expression of SERPINA5 protein
|
CTD |
PMID:14551147 |
|
NCBI chr 6:123,009,224...123,028,412
Ensembl chr 6:128,784,991...128,793,186
|
|
| G
|
Serpinb3
|
serpin family B member 3
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of SERPINB3 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr13:23,274,120...23,280,660
Ensembl chr13:23,788,758...23,795,298
|
|
| G
|
Serpinc1
|
serpin family C member 1
|
multiple interactions
|
ISO
|
[Ethinyl Estradiol co-treated with Levonorgestrel] results in decreased activity of SERPINC1 protein; [Ethinyl Estradiol co-treated with Levonorgestrel] results in decreased expression of SERPINC1 protein
|
CTD |
PMID:12618251 PMID:14981370 PMID:15288212 |
|
NCBI chr13:75,790,558...75,804,826
Ensembl chr13:75,790,546...75,817,643
|
|
| G
|
Serpine1
|
serpin family E member 1
|
multiple interactions
|
ISO
|
[Ethinyl Estradiol co-treated with Levonorgestrel] results in decreased activity of SERPINE1 protein; [Ethinyl Estradiol co-treated with Levonorgestrel] results in decreased expression of SERPINE1 protein
|
CTD |
PMID:14981370 PMID:15157790 PMID:15288212 |
|
NCBI chr12:25,237,977...25,248,356
Ensembl chr12:25,237,952...25,248,357
|
|
| G
|
Sfrp5
|
secreted frizzled-related protein 5
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of SFRP5 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr 1:241,006,762...241,011,224
Ensembl chr 1:250,956,050...250,960,512
|
|
| G
|
Shbg
|
sex hormone binding globulin
|
affects binding multiple interactions
|
ISO
|
Levonorgestrel binds to SHBG protein [Ethinyl Estradiol co-treated with Levonorgestrel] results in increased expression of SHBG protein
|
CTD |
PMID:12586319 PMID:14981370 PMID:17519148 |
|
NCBI chr10:54,831,716...54,849,162
Ensembl chr10:54,831,718...54,838,760
|
|
| G
|
Skic3
|
SKI3 subunit of superkiller complex
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of SKIC3 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr 2:5,631,544...5,783,643
Ensembl chr 2:7,363,535...7,483,496
|
|
| G
|
Slc16a9
|
solute carrier family 16, member 9
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of SLC16A9 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr20:18,334,946...18,376,195
Ensembl chr20:18,334,946...18,376,195
|
|
| G
|
Slc25a2
|
solute carrier family 25 member 2
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of SLC25A2 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr18:29,704,182...29,707,563
Ensembl chr18:29,703,871...29,708,827
|
|
| G
|
Slc2a5
|
solute carrier family 2 member 5
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of SLC2A5 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr 5:160,583,055...160,609,994
Ensembl chr 5:165,866,172...165,894,038
|
|
| G
|
Smyd2
|
SET and MYND domain containing 2
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of SMYD2 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr13:101,425,270...101,466,576
Ensembl chr13:103,956,473...103,997,774
|
|
| G
|
Snrpn
|
small nuclear ribonucleoprotein polypeptide N
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of SNRPN mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr 1:111,101,327...111,123,400
Ensembl chr 1:120,315,556...120,323,924
|
|
| G
|
Sobp
|
sine oculis binding protein homolog
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of SOBP mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr20:48,064,445...48,243,607
Ensembl chr20:48,064,445...48,243,607
|
|
| G
|
Spin4
|
spindlin family, member 4
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of SPIN4 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr X:59,888,728...59,892,817
Ensembl chr X:63,900,148...63,903,811
|
|
| G
|
Sptbn1
|
spectrin, beta, non-erythrocytic 1
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of SPTBN1 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr14:108,042,629...108,217,884
Ensembl chr14:108,042,629...108,217,836
|
|
| G
|
Srgn
|
serglycin
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of SRGN mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr20:30,985,508...31,022,296
Ensembl chr20:30,985,508...31,000,327
|
|
| G
|
Stxbp5l
|
syntaxin binding protein 5L
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of STXBP5L mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr11:63,334,667...63,654,270
Ensembl chr11:76,838,900...77,161,306
|
|
| G
|
Syt11
|
synaptotagmin 11
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of SYT11 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr 2:176,503,845...176,530,354
Ensembl chr 2:176,503,845...176,529,775
|
|
| G
|
Thrb
|
thyroid hormone receptor beta
|
multiple interactions
|
ISO
|
Levonorgestrel binds to and results in increased activity of THRB protein
|
CTD |
PMID:33049310 |
|
NCBI chr15:7,685,180...8,031,920
Ensembl chr15:10,115,954...10,313,680
|
|
| G
|
Tmem217
|
transmembrane protein 217
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of TMEM217 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr20:7,594,223...7,620,628
Ensembl chr20:7,594,405...7,620,558
|
|
| G
|
Tmem225
|
transmembrane protein 225
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of TMEM225 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr 8:40,497,483...40,500,041
Ensembl chr 8:49,394,504...49,397,485
|
|
| G
|
Tmem35a
|
transmembrane protein 35A
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of TMEM35A mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr X:97,503,350...97,514,198
Ensembl chr X:101,796,623...101,807,470
|
|
| G
|
Tmod2
|
tropomodulin 2
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of TMOD2 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr 8:85,197,222...85,250,627
Ensembl chr 8:85,196,226...85,246,371
|
|
| G
|
Tnf
|
tumor necrosis factor
|
multiple interactions
|
ISO
|
[Ethinyl Estradiol co-treated with Levonorgestrel] results in increased expression of TNF protein
|
CTD |
PMID:15769986 |
|
NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
|
|
| G
|
Tnfrsf11b
|
TNF receptor superfamily member 11B
|
increases expression
|
ISO
|
Levonorgestrel results in increased expression of TNFRSF11B mRNA
|
CTD |
PMID:16114553 |
|
NCBI chr 7:87,456,318...87,484,324
Ensembl chr 7:87,456,319...87,485,075
|
|
| G
|
Tnfsf11
|
TNF superfamily member 11
|
decreases expression
|
ISO
|
Levonorgestrel results in decreased expression of TNFSF11 mRNA
|
CTD |
PMID:16114553 |
|
NCBI chr15:53,673,850...53,705,325
Ensembl chr15:60,083,008...60,114,479
|
|
| G
|
Tnrc6b
|
trinucleotide repeat containing adaptor 6B
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of TNRC6B mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr 7:114,132,574...114,350,010
Ensembl chr 7:114,132,573...114,342,973
|
|
| G
|
Tra2a
|
transformer 2 alpha
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of TRA2A mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr 4:79,551,699...79,570,621
Ensembl chr 4:79,551,542...79,570,619
|
|
| G
|
Trmt13
|
tRNA methyltransferase 13 homolog
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of TRMT13 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr 2:204,533,630...204,547,711
Ensembl chr 2:207,218,552...207,231,701
|
|
| G
|
Ubap1
|
ubiquitin-associated protein 1
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of UBAP1 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr 5:56,520,722...56,561,153
Ensembl chr 5:61,316,643...61,357,076
|
|
| G
|
Ube2d3
|
ubiquitin-conjugating enzyme E2D 3
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of UBE2D3 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr 2:226,543,194...226,571,001
Ensembl chr 2:226,540,531...226,573,144
|
|
| G
|
Vcam1
|
vascular cell adhesion molecule 1
|
multiple interactions
|
ISO
|
[Ethinyl Estradiol co-treated with Levonorgestrel] results in decreased expression of VCAM1 protein
|
CTD |
PMID:15769986 |
|
NCBI chr 2:206,723,050...206,742,783
Ensembl chr 2:206,723,044...206,742,801
|
|
| G
|
Vdr
|
vitamin D receptor
|
multiple interactions
|
ISO
|
VDR gene polymorphism affects the reaction [[Ethinyl Estradiol co-treated with Levonorgestrel] affects the expression of ALPL protein]; VDR gene polymorphism affects the reaction [[Ethinyl Estradiol co-treated with Levonorgestrel] affects the expression of BGLAP protein]
|
CTD |
PMID:12521655 |
|
NCBI chr 7:128,987,981...129,037,677
Ensembl chr 7:130,866,745...130,916,757
|
|
| G
|
Vegfa
|
vascular endothelial growth factor A
|
increases expression
|
ISO
|
Levonorgestrel results in increased expression of VEGFA mRNA; Levonorgestrel results in increased expression of VEGFA mRNA alternative form
|
CTD |
PMID:17010073 |
|
NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194
|
|
| G
|
Xylt1
|
xylosyltransferase 1
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of XYLT1 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr 1:171,643,925...171,929,774
Ensembl chr 1:181,078,222...181,361,047
|
|
| G
|
Yeats2
|
YEATS domain containing 2
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of YEATS2 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr11:94,247,538...94,333,652
Ensembl chr11:94,247,538...94,333,292
|
|
| G
|
Zcchc7
|
zinc finger CCHC-type containing 7
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of ZCCHC7 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr 5:58,992,558...59,173,308
Ensembl chr 5:63,788,217...63,968,549
|
|
| G
|
Zeb2
|
zinc finger E-box binding homeobox 2
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of ZEB2 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr 3:49,624,028...49,754,323
Ensembl chr 3:49,624,028...49,754,323
|
|
| G
|
Zfand6
|
zinc finger AN1-type containing 6
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of ZFAND6 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr 1:147,990,099...148,061,221
Ensembl chr 1:147,990,108...148,061,134
|
|
| G
|
Zfp518a
|
zinc finger protein 518A
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of ZNF518A mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr 1:249,668,815...249,694,401
Ensembl chr 1:249,657,809...249,695,569
|
|
| G
|
Zfp638
|
zinc finger protein 638
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of ZNF638 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr 4:117,913,528...118,032,644
Ensembl chr 4:117,913,545...118,032,643
|
|
| G
|
Zfr
|
zinc finger RNA binding protein
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of ZFR mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr 2:61,137,611...61,200,322
Ensembl chr 2:62,864,338...62,929,133
|
|
| G
|
Zkscan7
|
zinc finger with KRAB and SCAN domains 7
|
multiple interactions
|
ISO
|
[testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of ZKSCAN7 mRNA
|
CTD |
PMID:19074003 |
|
NCBI chr 8:122,501,938...122,519,600
Ensembl chr 8:131,378,013...131,397,065
|
|
|
|
| G
|
Ar
|
androgen receptor
|
affects binding multiple interactions
|
EXP ISO
|
Medroxyprogesterone binds to AR protein Medroxyprogesterone binds to and results in decreased activity of AR protein; Medroxyprogesterone binds to and results in increased activity of AR protein
|
CTD |
PMID:14565775 PMID:25752796 |
|
NCBI chr X:67,135,317...67,304,476
Ensembl chr X:67,135,317...67,304,467
|
|
| G
|
Cat
|
catalase
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Medroxyprogesterone] affects the activity of CAT protein
|
CTD |
PMID:16584521 |
|
NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526
|
|
| G
|
Cyp2c79
|
cytochrome P450, family 2, subfamily c, polypeptide 79
|
decreases activity
|
ISO
|
Medroxyprogesterone results in decreased activity of CYP2C8 protein
|
CTD |
PMID:15601807 |
|
|
|
| G
|
Fshb
|
follicle stimulating hormone subunit beta
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Medroxyprogesterone] affects the expression of FSHB protein
|
CTD |
PMID:16584521 |
|
NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:114,003,262...114,007,072
|
|
| G
|
Lpo
|
lactoperoxidase
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Medroxyprogesterone] affects the expression of LPO protein
|
CTD |
PMID:16584521 |
|
NCBI chr10:72,606,950...72,626,220
Ensembl chr10:73,104,188...73,123,456
|
|
| G
|
Pgr
|
progesterone receptor
|
multiple interactions
|
ISO
|
Medroxyprogesterone binds to and results in increased activity of PGR protein
|
CTD |
PMID:25752796 |
|
NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:14,354,398...14,413,271
|
|
| G
|
Slc22a2
|
solute carrier family 22 member 2
|
multiple interactions
|
ISO
|
Medroxyprogesterone inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium]
|
CTD |
PMID:21599003 |
|
NCBI chr 1:50,668,817...50,711,019
Ensembl chr 1:50,668,817...50,711,019
|
|
|
|
| G
|
Abcb11
|
ATP binding cassette subfamily B member 11
|
decreases activity
|
ISO
|
Medroxyprogesterone Acetate results in decreased activity of ABCB11 protein
|
CTD |
PMID:23956101 |
|
NCBI chr 3:74,424,620...74,520,646
Ensembl chr 3:74,424,979...74,520,581
|
|
| G
|
Ackr1
|
atypical chemokine receptor 1
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of ACKR1 mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr13:85,782,396...85,784,015
Ensembl chr13:88,293,188...88,317,807
|
|
| G
|
Acp3
|
acid phosphatase 3
|
decreases expression
|
ISO
|
Medroxyprogesterone Acetate results in decreased expression of ACP3 mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr 8:113,784,372...113,833,033
Ensembl chr 8:113,785,032...113,833,033
|
|
| G
|
Acsl1
|
acyl-CoA synthetase long-chain family member 1
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of ACSL1 mRNA
|
CTD |
PMID:18497975 |
|
NCBI chr16:52,487,870...52,554,110
Ensembl chr16:52,487,870...52,554,023
|
|
| G
|
Adamts1
|
ADAM metallopeptidase with thrombospondin type 1 motif, 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of ADAMTS1 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr11:38,418,565...38,427,384
Ensembl chr11:38,418,101...38,427,390
|
|
| G
|
Adora3
|
adenosine A3 receptor
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of ADORA3 mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr 2:196,077,042...196,080,686
Ensembl chr 2:196,077,042...196,080,686
|
|
| G
|
Agt
|
angiotensinogen
|
multiple interactions
|
ISO
|
AGT protein promotes the reaction [[Medroxyprogesterone Acetate co-treated with Bucladesine] results in increased expression of and results in increased localization of FOXO1 protein]; AGT protein promotes the reaction [[Medroxyprogesterone Acetate co-treated with Bucladesine] results in increased secretion of PRL protein]; Losartan inhibits the reaction [AGT protein promotes the reaction [[Medroxyprogesterone Acetate co-treated with Bucladesine] results in increased secretion of PRL protein]]
|
CTD |
PMID:36682589 |
|
NCBI chr19:69,426,540...69,447,017
Ensembl chr19:69,421,638...69,446,944
|
|
| G
|
Ahr
|
aryl hydrocarbon receptor
|
multiple interactions
|
ISO
|
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[IFNG protein co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of AHR mRNA]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[Kynurenine co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of AHR mRNA]; [IFNG protein co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of AHR mRNA; [Kynurenine co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of AHR mRNA
|
CTD |
PMID:32781018 |
|
NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:57,961,423...57,998,901
|
|
| G
|
Aif1
|
allograft inflammatory factor 1
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of AIF1 mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr20:3,651,435...3,657,341
Ensembl chr20:3,652,243...3,657,339
|
|
| G
|
Ak5
|
adenylate kinase 5
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of AK5 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 2:241,397,297...241,581,483
Ensembl chr 2:244,057,240...244,241,366
|
|
| G
|
Akr1c1
|
aldo-keto reductase family 1, member C1
|
decreases expression increases expression decreases activity
|
ISO
|
Medroxyprogesterone Acetate results in decreased expression of AKR1C1 mRNA Medroxyprogesterone Acetate results in increased expression of AKR1C1 mRNA Medroxyprogesterone Acetate results in decreased activity of AKR1C1 protein
|
CTD |
PMID:12604236 PMID:18497975 PMID:21182831 PMID:23183084 |
|
NCBI chr17:70,720,397...70,747,285
Ensembl chr17:70,720,398...70,747,247
|
|
| G
|
Akr1c2
|
aldo-keto reductase family 1, member C2
|
decreases activity
|
ISO
|
Medroxyprogesterone Acetate results in decreased activity of AKR1C2 protein
|
CTD |
PMID:12604236 PMID:22245609 |
|
NCBI chr17:70,669,684...70,717,935
Ensembl chr17:70,669,710...70,685,686
|
|
| G
|
Akr1c3
|
aldo-keto reductase family 1, member C3
|
multiple interactions decreases activity
|
ISO
|
[Medroxyprogesterone Acetate inhibits the reaction [[AKR1C3 protein results in increased metabolism of Prostaglandin D2] which results in increased abundance of Dinoprost]] which results in increased abundance of 15-deoxy-delta(12,14)-prostaglandin J2; Medroxyprogesterone Acetate inhibits the reaction [[AKR1C3 protein co-treated with NADP] results in increased reduction of cyclopentanone]; Medroxyprogesterone Acetate inhibits the reaction [[AKR1C3 protein results in increased metabolism of Prostaglandin D2] which results in increased abundance of Dinoprost] Medroxyprogesterone Acetate results in decreased activity of AKR1C3 protein
|
CTD |
PMID:12604236 PMID:19997560 PMID:21182831 PMID:23261716 |
|
NCBI chr17:71,020,884...71,037,779
Ensembl chr17:70,970,900...71,048,438
|
|
| G
|
Alcam
|
activated leukocyte cell adhesion molecule
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of ALCAM mRNA
|
CTD |
PMID:18497975 PMID:20843944 |
|
NCBI chr11:61,804,932...62,005,250
Ensembl chr11:61,805,049...62,006,876
|
|
| G
|
Alox5ap
|
arachidonate 5-lipoxygenase activating protein
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of ALOX5AP mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr12:10,785,254...10,809,295
Ensembl chr12:10,785,257...10,817,038
|
|
| G
|
Antxr1
|
ANTXR cell adhesion molecule 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of ANTXR1 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 4:121,148,102...121,335,549
Ensembl chr 4:121,148,103...121,336,892
|
|
| G
|
Anxa2
|
annexin A2
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of ANXA2 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 8:78,986,252...79,022,638
Ensembl chr 8:78,986,242...79,022,631
|
|
| G
|
Apod
|
apolipoprotein D
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of APOD mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr11:82,936,216...82,957,264
Ensembl chr11:82,936,038...82,957,263
|
|
| G
|
Aqp3
|
aquaporin 3 (Gill blood group)
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of AQP3 mRNA
|
CTD |
PMID:18497975 |
|
NCBI chr 5:61,035,165...61,040,683
Ensembl chr 5:61,035,166...61,040,685
|
|
| G
|
Ar
|
androgen receptor
|
affects binding increases activity
|
ISO EXP
|
Medroxyprogesterone Acetate binds to AR protein Medroxyprogesterone Acetate results in increased activity of AR protein
|
CTD |
PMID:11861974 PMID:14565775 PMID:14751673 |
|
NCBI chr X:67,135,317...67,304,476
Ensembl chr X:67,135,317...67,304,467
|
|
| G
|
Arhgef19
|
Rho guanine nucleotide exchange factor 19
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of ARHGEF19 mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr 5:153,536,038...153,554,203
Ensembl chr 5:158,818,932...158,837,196
|
|
| G
|
Arhgef2
|
Rho/Rac guanine nucleotide exchange factor 2
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of ARHGEF2 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 2:176,358,909...176,416,178
Ensembl chr 2:176,358,904...176,417,646
|
|
| G
|
Atp11a
|
ATPase phospholipid transporting 11A
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of ATP11A mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr16:76,657,752...76,767,640
Ensembl chr16:83,359,884...83,469,767
|
|
| G
|
Atp1a1
|
ATPase Na+/K+ transporting subunit alpha 1
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of ATP1A1 mRNA
|
CTD |
PMID:15866426 |
|
NCBI chr 2:191,709,311...191,737,414
Ensembl chr 2:191,709,311...191,737,425
|
|
| G
|
Atp2b1
|
ATPase plasma membrane Ca2+ transporting 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of ATP2B1 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 7:35,622,267...35,731,904
Ensembl chr 7:35,622,461...35,731,904
|
|
| G
|
Atp2b4
|
ATPase plasma membrane Ca2+ transporting 4
|
decreases expression
|
ISO
|
Medroxyprogesterone Acetate results in decreased expression of ATP2B4 mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr13:45,156,137...45,255,292
Ensembl chr13:47,711,121...47,758,876
|
|
| G
|
Atp6v0c
|
ATPase H+ transporting V0 subunit C
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of ATP6V0C mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr10:13,196,204...13,202,580
Ensembl chr10:13,700,764...13,706,245
|
|
| G
|
Azgp1
|
alpha-2-glycoprotein 1, zinc-binding
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of AZGP1 mRNA
|
CTD |
PMID:15866426 |
|
NCBI chr12:22,044,685...22,051,248
Ensembl chr12:22,044,751...22,053,020
|
|
| G
|
Bax
|
BCL2 associated X, apoptosis regulator
|
multiple interactions
|
ISO
|
[Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of BAX protein
|
CTD |
PMID:16709600 |
|
NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429
|
|
| G
|
Bcat1
|
branched chain amino acid transaminase 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of BCAT1 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 4:179,695,662...179,777,973
Ensembl chr 4:179,695,662...179,777,288
|
|
| G
|
Bckdk
|
branched chain ketoacid dehydrogenase kinase
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of BCKDK mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 1:191,945,809...191,950,480
Ensembl chr 1:191,946,471...191,953,453
|
|
| G
|
Bcl2l11
|
Bcl2-like 11
|
multiple interactions
|
ISO
|
[Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of BCL2L11 protein
|
CTD |
PMID:16709600 |
|
NCBI chr 3:135,820,042...135,857,330
Ensembl chr 3:135,817,562...135,960,695
|
|
| G
|
Bcl2l13
|
Bcl2-like 13
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of BCL2L13 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 4:154,056,116...154,112,890
Ensembl chr 4:155,728,284...155,781,158
|
|
| G
|
Bdkrb1
|
bradykinin receptor B1
|
decreases expression
|
ISO
|
Medroxyprogesterone Acetate results in decreased expression of BDKRB1 mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr 6:130,275,631...130,284,968
Ensembl chr 6:130,275,478...130,280,973
|
|
| G
|
Bet1l
|
Bet1 golgi vesicular membrane trafficking protein-like
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of BET1L mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 1:195,931,407...195,935,072
Ensembl chr 1:205,361,041...205,364,706
|
|
| G
|
Bicd1
|
BICD cargo adaptor 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of BICD1 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 4:182,479,071...182,631,504
Ensembl chr 4:184,210,363...184,357,391
|
|
| G
|
Bsnd
|
barttin CLCNK type accessory subunit beta
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of BSND mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 5:121,251,774...121,260,571
Ensembl chr 5:126,480,592...126,489,389
|
|
| G
|
C1qa
|
complement C1q A chain
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of C1QA mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr 5:154,417,086...154,419,933
Ensembl chr 5:154,417,087...154,427,732
|
|
| G
|
C1qb
|
complement C1q B chain
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of C1QB mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr 5:154,402,276...154,407,827
Ensembl chr 5:154,402,279...154,407,840
|
|
| G
|
C1qc
|
complement C1q C chain
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of C1QC mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr 5:154,410,845...154,414,208
Ensembl chr 5:154,410,848...154,414,468
|
|
| G
|
C1r
|
complement C1r
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of C1R mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 4:157,412,718...157,423,483
Ensembl chr 4:159,098,918...159,109,714
|
|
| G
|
C2cd4b
|
C2 calcium-dependent domain containing 4B
|
decreases expression
|
ISO
|
Medroxyprogesterone Acetate results in decreased expression of NLF2 mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr 8:77,254,327...77,277,620
Ensembl chr 8:77,238,551...77,279,879
|
|
| G
|
C2h1orf162
|
similar to human chromosome 1 open reading frame 162
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of C1ORF162 mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr 2:193,410,730...193,420,824
Ensembl chr 2:196,100,702...196,106,832
|
|
| G
|
C3
|
complement C3
|
multiple interactions
|
EXP
|
Medroxyprogesterone Acetate inhibits the reaction [Ethinyl Estradiol results in increased expression of C3 mRNA]; Mifepristone inhibits the reaction [Medroxyprogesterone Acetate inhibits the reaction [Ethinyl Estradiol results in increased expression of C3 mRNA]]
|
CTD |
PMID:11566438 PMID:16806946 |
|
NCBI chr 9:2,174,412...2,201,339
Ensembl chr 9:2,174,412...2,201,339
|
|
| G
|
C3h15orf48
|
similar to human chromosome 15 open reading frame 48
|
decreases expression
|
ISO
|
Medroxyprogesterone Acetate results in decreased expression of C15ORF48 mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr 3:109,719,952...109,723,505
Ensembl chr 3:130,173,416...130,177,089
|
|
| G
|
Ca8
|
carbonic anhydrase 8
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of CA8 mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr 5:26,102,767...26,199,819
Ensembl chr 5:26,102,813...26,199,796
|
|
| G
|
Calm1
|
calmodulin 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of CALM1 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 6:125,217,191...125,227,855
Ensembl chr 6:125,217,246...125,225,381
|
|
| G
|
Capn2
|
calpain 2
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of CAPN2 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr13:96,681,902...96,732,625
Ensembl chr13:96,681,848...96,732,625
|
|
| G
|
Car2
|
carbonic anhydrase 2
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of CA2 mRNA
|
CTD |
PMID:18497975 |
|
NCBI chr 2:88,462,883...88,478,012
Ensembl chr 2:88,462,872...88,478,064
|
|
| G
|
Cast
|
calpastatin
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of CAST mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 2:3,973,112...4,082,658
Ensembl chr 2:5,707,640...5,817,180
|
|
| G
|
Cat
|
catalase
|
multiple interactions
|
ISO
|
[Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of CAT mRNA
|
CTD |
PMID:16709600 |
|
NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526
|
|
| G
|
Cav2
|
caveolin 2
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of CAV2 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 4:45,616,766...45,624,144
Ensembl chr 4:46,582,096...46,591,425
|
|
| G
|
Ccl2
|
C-C motif chemokine ligand 2
|
decreases expression decreases secretion
|
EXP
|
Medroxyprogesterone Acetate results in decreased expression of CCL2 mRNA; Medroxyprogesterone Acetate results in decreased expression of CCL2 protein Medroxyprogesterone Acetate results in decreased secretion of CCL2 protein
|
CTD |
PMID:18606702 |
|
NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875
|
|
| G
|
Ccn2
|
cellular communication network factor 2
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of CCN2 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 1:22,621,498...22,624,614
Ensembl chr 1:22,621,501...22,624,976
|
|
| G
|
Ccnb1
|
cyclin B1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Medroxyprogesterone Acetate co-treated with Bucladesine co-treated with decitabine] results in increased expression of CCNB1 mRNA; [Estradiol co-treated with Medroxyprogesterone Acetate co-treated with Bucladesine] results in increased expression of CCNB1 protein
|
CTD |
PMID:22534328 |
|
NCBI chr 2:33,646,252...33,655,225
Ensembl chr 2:33,646,252...33,655,225
|
|
| G
|
Ccnd1
|
cyclin D1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Medroxyprogesterone Acetate co-treated with Bucladesine co-treated with decitabine] affects the expression of CCND1 protein; [Estradiol co-treated with Medroxyprogesterone Acetate co-treated with Bucladesine co-treated with decitabine] results in decreased expression of CCND1 mRNA; [Estradiol co-treated with Medroxyprogesterone Acetate co-treated with Bucladesine] results in decreased expression of CCND1 mRNA; [Estradiol co-treated with Medroxyprogesterone Acetate co-treated with Bucladesine] results in decreased expression of CCND1 protein
|
CTD |
PMID:22534328 |
|
NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810
|
|
| G
|
Cd163
|
CD163 molecule
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of CD163 mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr 4:158,770,751...158,804,146
Ensembl chr 4:158,770,749...158,804,146
|
|
| G
|
Cd40lg
|
CD40 ligand
|
multiple interactions decreases activity
|
ISO
|
[Bezafibrate co-treated with Medroxyprogesterone Acetate] results in decreased activity of CD40LG protein Medroxyprogesterone Acetate results in decreased activity of CD40LG protein
|
CTD |
PMID:18923439 |
|
NCBI chr X:140,164,341...140,176,057
Ensembl chr X:140,164,302...140,176,475
|
|
| G
|
Cdc42bpa
|
CDC42 binding protein kinase alpha
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of CDC42BPA mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr13:94,215,359...94,435,681
Ensembl chr13:94,215,959...94,435,681
|
|
| G
|
Cdkn1a
|
cyclin-dependent kinase inhibitor 1A
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of CDKN1A mRNA; [Estradiol co-treated with Medroxyprogesterone Acetate co-treated with Bucladesine co-treated with decitabine] results in increased expression of CDKN1A mRNA; [Estradiol co-treated with Medroxyprogesterone Acetate co-treated with Bucladesine] results in increased expression of CDKN1A protein
|
CTD |
PMID:20823114 PMID:22534328 |
|
NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969
|
|
| G
|
Cdkn1b
|
cyclin-dependent kinase inhibitor 1B
|
multiple interactions increases expression
|
ISO
|
Estradiol promotes the reaction [Medroxyprogesterone Acetate results in increased expression of CDKN1B protein]; Mifepristone inhibits the reaction [[Medroxyprogesterone Acetate co-treated with Estradiol] results in increased expression of CDKN1B protein]
|
CTD |
PMID:17283133 |
|
NCBI chr 4:169,491,273...169,496,500
Ensembl chr 4:169,490,876...169,496,498
|
|
| G
|
Cebpz
|
CCAAT/enhancer binding protein zeta
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of CEBPZ mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 6:16,119,871...16,137,600
Ensembl chr 6:21,872,025...21,889,749
|
|
| G
|
Cflar
|
CASP8 and FADD-like apoptosis regulator
|
multiple interactions
|
ISO
|
[Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of CFLAR protein alternative form
|
CTD |
PMID:16709600 |
|
NCBI chr 9:67,679,502...67,747,226
Ensembl chr 9:67,679,559...67,726,434
|
|
| G
|
Cilp
|
cartilage intermediate layer protein
|
decreases expression
|
ISO
|
Medroxyprogesterone Acetate results in decreased expression of CILP mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr 8:74,671,696...74,687,420
Ensembl chr 8:74,671,534...74,687,409
|
|
| G
|
Cldn5
|
claudin 5
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of CLDN5 mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr11:95,717,172...95,718,598
Ensembl chr11:95,717,176...95,719,322
|
|
| G
|
Cngb1
|
cyclic nucleotide gated channel subunit beta 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of CNGB1 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr19:9,732,646...9,798,864
Ensembl chr19:9,732,646...9,797,224
|
|
| G
|
Cnr1
|
cannabinoid receptor 1
|
increases expression multiple interactions
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of CNR1 mRNA [Medroxyprogesterone Acetate co-treated with Estradiol co-treated with Colforsin] results in increased expression of CNR1 mRNA
|
CTD |
PMID:20843944 PMID:31154070 |
|
NCBI chr 5:53,204,867...53,230,396
Ensembl chr 5:53,204,260...53,239,252
|
|
| G
|
Cnr2
|
cannabinoid receptor 2
|
multiple interactions
|
ISO
|
[Medroxyprogesterone Acetate co-treated with Estradiol co-treated with Colforsin] results in increased expression of CNR2 mRNA
|
CTD |
PMID:31154070 |
|
NCBI chr 5:153,408,968...153,435,092
Ensembl chr 5:153,409,147...153,435,961
|
|
| G
|
Col6a2
|
collagen type VI alpha 2 chain
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of COL6A2 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr20:12,021,676...12,049,425
Ensembl chr20:12,021,265...12,057,042
|
|
| G
|
Col6a3
|
collagen type VI alpha 3 chain
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of COL6A3 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 9:91,361,578...91,439,434
Ensembl chr 9:98,809,171...98,886,990
|
|
| G
|
Cox6a2
|
cytochrome c oxidase subunit 6A2
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of COX6A2 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 1:192,218,970...192,221,188
Ensembl chr 1:192,218,970...192,219,716
|
|
| G
|
Cplx1
|
complexin 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of CPLX1 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr14:1,184,677...1,216,392
Ensembl chr14:1,329,032...1,360,769
|
|
| G
|
Crebbp
|
CREB binding protein
|
multiple interactions
|
ISO
|
Medroxyprogesterone Acetate promotes the reaction [CREBBP protein binds to SOD2 promoter]
|
CTD |
PMID:20685861 |
|
NCBI chr10:11,842,307...11,968,266
Ensembl chr10:11,822,620...11,968,266
|
|
| G
|
Crem
|
cAMP responsive element modulator
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of CREM mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr17:58,932,011...59,001,160
Ensembl chr17:58,934,147...59,001,160
|
|
| G
|
Crp
|
C-reactive protein
|
multiple interactions
|
ISO
|
[Estrogens, Conjugated (USP) co-treated with Medroxyprogesterone Acetate] results in increased expression of CRP protein
|
CTD |
PMID:15990257 PMID:17882670 |
|
NCBI chr13:87,694,062...87,695,978
Ensembl chr13:87,657,317...87,707,514
|
|
| G
|
Ctps2
|
CTP synthase 2
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of CTPS2 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr X:35,277,658...35,418,505
Ensembl chr X:35,277,658...35,418,505
|
|
| G
|
Ctsd
|
cathepsin D
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of CTSD mRNA
|
CTD |
PMID:18497975 |
|
NCBI chr 1:206,956,945...206,968,821
Ensembl chr 1:206,956,944...206,968,821
|
|
| G
|
Cyb5d1
|
cytochrome b5 domain containing 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of CYB5D1 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr10:54,612,230...54,616,375
Ensembl chr10:54,612,230...54,616,713
|
|
| G
|
Cybb
|
cytochrome b-245 beta chain
|
multiple interactions
|
EXP
|
[Medroxyprogesterone Acetate co-treated with Estradiol] results in increased expression of CYBB protein
|
CTD |
PMID:21670166 |
|
NCBI chr X:16,030,596...16,065,065
Ensembl chr X:16,030,596...16,065,065
|
|
| G
|
Cyp19a1
|
cytochrome P450, family 19, subfamily a, polypeptide 1
|
multiple interactions
|
ISO
|
[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of CYP19A1 mRNA; Cannabidiol inhibits the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of CYP19A1 mRNA]; Dronabinol inhibits the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of CYP19A1 mRNA]
|
CTD |
PMID:31953017 |
|
NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:63,449,148...63,476,917
|
|
| G
|
Cyp1a1
|
cytochrome P450, family 1, subfamily a, polypeptide 1
|
multiple interactions increases expression
|
ISO
|
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[IFNG protein co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of CYP1A1 mRNA]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[Kynurenine co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of CYP1A1 mRNA]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[Tryptophan co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of CYP1A1 mRNA]; [IFNG protein co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of CYP1A1 mRNA; [Kynurenine co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of CYP1A1 mRNA; [Tryptophan co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of CYP1A1 mRNA; Medroxyprogesterone Acetate inhibits the reaction [benzo(a)pyrene 7,8-dihydrodiol results in increased expression of CYP1A1 mRNA] Medroxyprogesterone Acetate results in increased expression of CYP1A1 mRNA
|
CTD |
PMID:10706104 PMID:20843944 PMID:32781018 |
|
NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012
|
|
| G
|
Cyp1b1
|
cytochrome P450, family 1, subfamily b, polypeptide 1
|
multiple interactions
|
ISO
|
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[IFNG protein co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of CYP1B1 mRNA]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[Kynurenine co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of CYP1B1 mRNA]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[Tryptophan co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of CYP1B1 mRNA]; [IFNG protein co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of CYP1B1 mRNA; [Kynurenine co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of CYP1B1 mRNA; [Tryptophan co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of CYP1B1 mRNA; CYP1B1 gene polymorphism affects the susceptibility to [Estrogens co-treated with Medroxyprogesterone Acetate]
|
CTD |
PMID:15987428 PMID:32781018 |
|
NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:21,078,146...21,103,142
|
|
| G
|
Cyp27b1
|
cytochrome P450, family 27, subfamily b, polypeptide 1
|
decreases expression
|
ISO
|
Medroxyprogesterone Acetate results in decreased expression of CYP27B1 mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr 7:64,756,626...64,761,570
Ensembl chr 7:64,756,626...64,761,570
|
|
| G
|
Cyp3a2
|
cytochrome P450, family 3, subfamily a, polypeptide 2
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of CYP3A4 mRNA; Medroxyprogesterone Acetate results in increased expression of CYP3A4 protein
|
CTD |
PMID:15650019 |
|
NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857
|
|
| G
|
Dcn
|
decorin
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of DCN protein; Azacitidine promotes the reaction [[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of DCN protein]
|
CTD |
PMID:20823114 |
|
NCBI chr 7:34,167,973...34,208,004
Ensembl chr 7:34,163,011...34,218,926
|
|
| G
|
Ddx27
|
DEAD-box helicase 27
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of DDX27 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 3:155,744,182...155,763,380
Ensembl chr 3:176,163,203...176,182,410
|
|
| G
|
Depp1
|
DEPP autophagy regulator 1
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of DEPP1 mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr 4:149,910,794...149,913,013
Ensembl chr 4:151,581,502...151,586,233
|
|
| G
|
Des
|
desmin
|
multiple interactions
|
EXP ISO
|
[Medroxyprogesterone Acetate co-treated with Bucladesine] results in increased expression of DES mRNA [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate co-treated with Azacitidine] results in increased expression of DES mRNA
|
CTD |
PMID:19089455 PMID:20823114 |
|
NCBI chr 9:76,850,979...76,858,695
Ensembl chr 9:84,298,447...84,307,347
|
|
| G
|
Dhx9
|
DExH-box helicase 9
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of DHX9 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr13:68,152,813...68,189,580
Ensembl chr13:68,152,813...68,189,546
|
|
| G
|
Dio2
|
iodothyronine deiodinase 2
|
decreases expression multiple interactions
|
ISO
|
Medroxyprogesterone Acetate results in decreased expression of DIO2 mRNA [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of DIO2 mRNA
|
CTD |
PMID:20823114 PMID:20843944 |
|
NCBI chr 6:109,665,523...109,679,809
Ensembl chr 6:115,396,308...115,410,594
|
|
| G
|
Dkk1
|
dickkopf WNT signaling pathway inhibitor 1
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of DKK1 mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr 1:228,381,521...228,385,202
Ensembl chr 1:237,794,969...237,798,650
|
|
| G
|
Dlg5
|
discs large MAGUK scaffold protein 5
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of DLG5 mRNA
|
CTD |
PMID:18497975 PMID:19146866 |
|
NCBI chr15:75,786...209,735
Ensembl chr15:125,290...237,332
|
|
| G
|
Dner
|
delta/notch-like EGF repeat containing
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of DNER mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr 9:85,586,985...85,902,461
Ensembl chr 9:93,035,108...93,350,568
|
|
| G
|
Dtymk
|
deoxythymidylate kinase
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of DTYMK mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 9:101,762,899...101,771,733
Ensembl chr 9:101,762,899...101,774,504
|
|
| G
|
Dusp23
|
dual specificity phosphatase 23
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of DUSP23 mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr13:87,630,245...87,632,400
Ensembl chr13:87,630,245...87,632,400
|
|
| G
|
Eda
|
ectodysplasin-A
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of EDA mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr X:65,078,454...65,480,172
Ensembl chr X:69,118,796...69,520,274
|
|
| G
|
Eef1a1
|
eukaryotic translation elongation factor 1 alpha 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of EEF1A1 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 8:88,221,839...88,225,688
Ensembl chr 8:88,221,843...88,225,072
|
|
| G
|
Efemp1
|
EGF containing fibulin extracellular matrix protein 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of EFEMP1 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr14:106,811,769...106,890,961
Ensembl chr14:106,802,304...106,892,808
|
|
| G
|
Efhd1
|
EF-hand domain family, member D1
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of EFHD1 mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr 9:95,386,155...95,432,800
Ensembl chr 9:95,386,169...95,432,798
|
|
| G
|
Egr2
|
early growth response 2
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of EGR2 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr20:21,050,149...21,055,201
Ensembl chr20:21,050,149...21,057,748
|
|
| G
|
Elf3
|
E74 like ETS transcription factor 3
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of ELF3 mRNA
|
CTD |
PMID:18497975 |
|
NCBI chr13:49,242,265...49,247,102
Ensembl chr13:49,242,267...49,247,380
|
|
| G
|
Enpp2
|
ectonucleotide pyrophosphatase/phosphodiesterase 2
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of ENPP2 mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr 7:88,092,140...88,214,758
Ensembl chr 7:88,092,140...88,214,957
|
|
| G
|
Epb41l4a
|
erythrocyte membrane protein band 4.1 like 4A
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of EPB41L4A mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr18:25,680,169...25,890,998
Ensembl chr18:25,680,171...25,888,498
|
|
| G
|
Epha3
|
Eph receptor A3
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of EPHA3 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr11:14,585,041...14,920,721
Ensembl chr11:14,586,727...14,920,425
|
|
| G
|
Ephx1
|
epoxide hydrolase 1
|
multiple interactions increases expression
|
ISO
|
ESR1 protein promotes the reaction [Medroxyprogesterone Acetate results in increased expression of EPHX1 protein] Medroxyprogesterone Acetate results in increased expression of EPHX1 mRNA; Medroxyprogesterone Acetate results in increased expression of EPHX1 protein
|
CTD |
PMID:20383792 |
|
NCBI chr13:95,246,079...95,275,852
Ensembl chr13:95,246,080...95,321,981
|
|
| G
|
Esr1
|
estrogen receptor 1
|
multiple interactions decreases expression
|
ISO
|
[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of ESR1 mRNA; Cadmium inhibits the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of ESR1 mRNA]; ESR1 protein promotes the reaction [Medroxyprogesterone Acetate results in increased expression of EPHX1 protein] Medroxyprogesterone Acetate results in decreased expression of ESR1 mRNA
|
CTD |
PMID:20383792 PMID:20843944 PMID:39892737 |
|
NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:43,644,392...43,900,354
|
|
| G
|
Eya1
|
EYA transcriptional coactivator and phosphatase 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of EYA1 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 5:4,863,501...5,101,483
Ensembl chr 5:9,646,591...9,884,614
|
|
| G
|
Ezh2
|
enhancer of zeste 2 polycomb repressive complex 2 subunit
|
multiple interactions decreases expression
|
ISO
|
[8-Bromo Cyclic Adenosine Monophosphate co-treated with Medroxyprogesterone Acetate] results in decreased expression of EZH2 mRNA; [8-Bromo Cyclic Adenosine Monophosphate co-treated with Medroxyprogesterone Acetate] results in decreased expression of EZH2 protein; EZH2 mutant form inhibits the reaction [[8-Bromo Cyclic Adenosine Monophosphate co-treated with Medroxyprogesterone Acetate] results in increased expression of IGFBP1 mRNA]; EZH2 mutant form inhibits the reaction [[8-Bromo Cyclic Adenosine Monophosphate co-treated with Medroxyprogesterone Acetate] results in increased expression of PRL mRNA] Medroxyprogesterone Acetate results in decreased expression of EZH2 mRNA; Medroxyprogesterone Acetate results in decreased expression of EZH2 protein
|
CTD |
PMID:21903722 |
|
NCBI chr 4:77,624,223...77,698,598
Ensembl chr 4:77,624,223...77,687,183
|
|
| G
|
F13a1
|
coagulation factor XIII A1 chain
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of F13A1 mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr17:28,021,197...28,197,960
Ensembl chr17:28,020,845...28,197,948
|
|
| G
|
F2
|
coagulation factor II, thrombin
|
multiple interactions increases expression
|
ISO EXP
|
Medroxyprogesterone Acetate promotes the reaction [F2 protein results in increased expression of F3 mRNA] Medroxyprogesterone Acetate results in increased expression of F2
|
CTD |
PMID:1828463 PMID:11733402 |
|
NCBI chr 3:98,051,958...98,065,246
Ensembl chr 3:98,051,960...98,065,246
|
|
| G
|
F2r
|
coagulation factor II (thrombin) receptor
|
increases expression multiple interactions
|
ISO EXP
|
Medroxyprogesterone Acetate results in increased expression of F2R protein Mifepristone inhibits the reaction [Medroxyprogesterone Acetate results in increased expression of F2R mRNA] Medroxyprogesterone Acetate results in increased expression of F2R mRNA; Medroxyprogesterone Acetate results in increased expression of F2R protein
|
CTD |
PMID:11733402 |
|
NCBI chr 2:26,869,343...26,885,856
Ensembl chr 2:28,604,066...28,620,579
|
|
| G
|
F3
|
coagulation factor III, tissue factor
|
multiple interactions increases expression
|
ISO EXP
|
Medroxyprogesterone Acetate promotes the reaction [F2 protein results in increased expression of F3 mRNA] Medroxyprogesterone Acetate results in increased expression of F3 protein
|
CTD |
PMID:11733402 PMID:16011840 |
|
NCBI chr 2:212,511,675...212,523,375
Ensembl chr 2:212,511,680...212,523,369
|
|
| G
|
F7
|
coagulation factor VII
|
decreases expression
|
ISO
|
Medroxyprogesterone Acetate results in decreased expression of F7
|
CTD |
PMID:1828463 |
|
NCBI chr16:83,191,896...83,202,775
Ensembl chr16:83,191,914...83,202,738
|
|
| G
|
F9
|
coagulation factor IX
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of F9
|
CTD |
PMID:1828463 |
|
NCBI chr X:143,388,642...143,433,143
Ensembl chr X:143,388,621...143,433,146
|
|
| G
|
Fads2
|
fatty acid desaturase 2
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of FADS2 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 1:216,132,277...216,172,190
Ensembl chr 1:216,133,676...216,172,066
|
|
| G
|
Fam107a
|
family with sequence similarity 107, member A
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of FAM107A mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr15:19,038,726...19,060,644
Ensembl chr15:19,038,616...19,065,219
|
|
| G
|
Fas
|
Fas cell surface death receptor
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of FAS mRNA
|
CTD |
PMID:18497975 |
|
NCBI chr 1:241,212,155...241,245,774
Ensembl chr 1:241,205,935...241,246,104
|
|
| G
|
Faslg
|
Fas ligand
|
multiple interactions
|
ISO
|
[Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of FASLG protein
|
CTD |
PMID:16709600 |
|
NCBI chr13:76,680,885...76,706,042
Ensembl chr13:76,688,243...76,695,503
|
|
| G
|
Fbln1
|
fibulin 1
|
increases expression multiple interactions
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of FBLN1 mRNA; Medroxyprogesterone Acetate results in increased expression of FBLN1 protein Mifepristone inhibits the reaction [Medroxyprogesterone Acetate results in increased expression of FBLN1 mRNA]
|
CTD |
PMID:15774544 |
|
NCBI chr 7:118,190,347...118,269,965
Ensembl chr 7:118,190,478...118,269,965
|
|
| G
|
Fbxo11
|
F-box protein 11
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of FBXO11 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 6:12,240,348...12,316,223
Ensembl chr 6:12,239,801...12,316,221
|
|
| G
|
Fbxw5
|
F-box and WD repeat domain containing 5
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of FBXW5 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 3:28,720,670...28,725,237
Ensembl chr 3:28,720,778...28,725,235
|
|
| G
|
Fcgbp
|
Fc gamma binding protein
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of FCGBP mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr 1:92,502,461...92,540,658
Ensembl chr 1:92,499,498...92,540,658
|
|
| G
|
Fgd1
|
FYVE, RhoGEF and PH domain containing 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of FGD1 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr X:20,023,746...20,066,734
Ensembl chr X:23,467,530...23,509,979
|
|
| G
|
Fgf7
|
fibroblast growth factor 7
|
decreases expression
|
ISO
|
Medroxyprogesterone Acetate results in decreased expression of FGF7 mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr 3:133,734,557...133,786,678
Ensembl chr 3:133,734,673...133,786,328
|
|
| G
|
Fibin
|
fin bud initiation factor homolog
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of FIBIN mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr 3:117,396,973...117,399,244
Ensembl chr 3:117,391,724...117,399,479
|
|
| G
|
Filip1l
|
filamin A interacting protein 1-like
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of FILIP1L mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr11:56,403,467...56,646,422
Ensembl chr11:56,410,582...56,646,402
|
|
| G
|
Fkbp5
|
FKBP prolyl isomerase 5
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of FKBP5 mRNA
|
CTD |
PMID:19146866 PMID:20843944 |
|
NCBI chr20:6,458,931...6,577,227
Ensembl chr20:6,458,940...6,543,118
|
|
| G
|
Fn1
|
fibronectin 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of FN1 mRNA; [Medroxyprogesterone Acetate co-treated with Carbon Tetrachloride] results in increased expression of FN1 protein
|
CTD |
PMID:1465320 PMID:20823114 |
|
NCBI chr 9:80,645,507...80,714,200
Ensembl chr 9:80,645,507...80,714,137
|
|
| G
|
Folr2
|
folate receptor beta
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of FOLR2 mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr 1:156,200,044...156,218,380
Ensembl chr 1:165,612,063...165,617,731
|
|
| G
|
Foxo1
|
forkhead box O1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate co-treated with Azacitidine] results in increased expression of FOXO1 mRNA; [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of FOXO1 mRNA; [Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of FOXO1 mRNA; [Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of FOXO1 protein; [Medroxyprogesterone Acetate co-treated with Bucladesine] results in increased expression of and results in increased localization of FOXO1 protein; [Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of FOXO1 mRNA; AGT protein promotes the reaction [[Medroxyprogesterone Acetate co-treated with Bucladesine] results in increased expression of and results in increased localization of FOXO1 protein]; Cadmium inhibits the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of FOXO1 mRNA]; Cannabidiol inhibits the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of FOXO1 mRNA]; FOXO1 protein affects the reaction [[Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in decreased expression of FOXO3 mRNA]; FOXO1 protein affects the reaction [[Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of SOD2 mRNA]; FOXO1 protein affects the reaction [[Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased secretion of IGFBP1 protein]; FOXO1 protein affects the reaction [[Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased secretion of PRL protein]; Hydrogen Peroxide inhibits the reaction [[Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of FOXO1 mRNA]; Hydrogen Peroxide inhibits the reaction [[Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of FOXO1 protein]
|
CTD |
PMID:16709600 PMID:20823114 PMID:31953017 PMID:36682589 PMID:39892737 |
|
NCBI chr 2:138,462,974...138,541,420
Ensembl chr 2:138,462,697...138,541,419
|
|
| G
|
Foxo3
|
forkhead box O3
|
multiple interactions
|
ISO
|
[Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] inhibits the reaction [Hydrogen Peroxide results in increased expression of FOXO3 mRNA]; [Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] inhibits the reaction [Hydrogen Peroxide results in increased expression of FOXO3 protein]; [Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in decreased expression of FOXO3 mRNA; FOXO1 protein affects the reaction [[Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in decreased expression of FOXO3 mRNA]
|
CTD |
PMID:16709600 |
|
NCBI chr20:47,251,968...47,348,254
Ensembl chr20:47,255,878...47,346,845
|
|
| G
|
Fpr1
|
formyl peptide receptor 1
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of FPR1 mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr 1:67,417,991...67,429,813
Ensembl chr 1:67,421,313...67,422,520
|
|
| G
|
Fscn2
|
fascin actin-bundling protein 2, retinal
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of FSCN2 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr10:106,121,038...106,139,683
Ensembl chr10:106,133,144...106,139,683
|
|
| G
|
Fshb
|
follicle stimulating hormone subunit beta
|
multiple interactions
|
ISO
|
[Estrogens, Conjugated (USP) co-treated with Medroxyprogesterone Acetate] results in decreased expression of FSHB protein
|
CTD |
PMID:16236362 |
|
NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:114,003,262...114,007,072
|
|
| G
|
Fxyd3
|
FXYD domain-containing ion transport regulator 3
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of FXYD3 mRNA
|
CTD |
PMID:18497975 |
|
NCBI chr 1:86,305,531...86,312,455
Ensembl chr 1:95,432,919...95,439,702
|
|
| G
|
Gadd45a
|
growth arrest and DNA-damage-inducible, alpha
|
multiple interactions
|
ISO
|
[Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of GADD45A mRNA; [Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of GADD45A protein
|
CTD |
PMID:16709600 |
|
NCBI chr 4:97,484,497...97,486,799
Ensembl chr 4:97,484,502...97,486,807
|
|
| G
|
Galnt15
|
polypeptide N-acetylgalactosaminyltransferase 15
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of GALNT15 mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr16:7,233,524...7,273,290
Ensembl chr16:7,233,606...7,273,285
|
|
| G
|
Gars1
|
glycyl-tRNA synthetase 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of GARS1 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 4:85,484,939...85,542,876
Ensembl chr 4:85,493,753...85,542,876
|
|
| G
|
Gbe1
|
1,4-alpha-glucan branching enzyme 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of GBE1 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr11:22,181,194...22,446,640
Ensembl chr11:22,181,103...22,446,638
|
|
| G
|
Gbp2
|
guanylate binding protein 2
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of GBP2 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 2:234,005,727...234,021,812
Ensembl chr 2:234,008,590...234,021,810
|
|
| G
|
Gcnt2
|
glucosaminyl (N-acetyl) transferase 2
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of GCNT2 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr17:23,796,859...23,901,625
Ensembl chr17:24,002,597...24,106,989
|
|
| G
|
Gdf10
|
growth differentiation factor 10
|
decreases expression
|
ISO
|
Medroxyprogesterone Acetate results in decreased expression of GDF10 mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr16:9,237,182...9,250,537
Ensembl chr16:9,243,317...9,256,794
|
|
| G
|
Gipc1
|
GIPC PDZ domain containing family, member 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of GIPC1 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr19:41,380,125...41,392,078
Ensembl chr19:41,380,125...41,391,725
|
|
| G
|
Gja1
|
gap junction protein, alpha 1
|
decreases expression
|
ISO
|
Medroxyprogesterone Acetate results in decreased expression of GJA1 mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr20:36,302,490...36,315,010
Ensembl chr20:36,302,352...36,319,689
|
|
| G
|
Glrx
|
glutaredoxin
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of GLRX mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr 2:7,073,737...7,083,548
Ensembl chr 2:7,073,759...7,083,543
|
|
| G
|
Gpkow
|
G patch domain and KOW motifs
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of GPKOW mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr X:14,791,601...14,806,384
Ensembl chr X:17,463,525...17,478,298
|
|
| G
|
Gpnmb
|
glycoprotein nmb
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of GPNMB mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 4:79,341,128...79,362,366
Ensembl chr 4:79,341,021...79,380,240
|
|
| G
|
Gpr34
|
G protein-coupled receptor 34
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of GPR34 mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr X:11,777,667...11,786,640
Ensembl chr X:11,776,371...11,843,240
|
|
| G
|
Gpr83
|
G protein-coupled receptor 83
|
decreases expression
|
ISO
|
Medroxyprogesterone Acetate results in decreased expression of GPR83 mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr 8:11,693,540...11,704,028
Ensembl chr 8:19,974,993...19,985,490
|
|
| G
|
Gpx3
|
glutathione peroxidase 3
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of GPX3 mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr10:39,028,624...39,036,695
Ensembl chr10:39,529,448...39,537,405
|
|
| G
|
Gsn
|
gelsolin
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of GSN mRNA
|
CTD |
PMID:18497975 |
|
NCBI chr 3:18,585,166...18,638,404
Ensembl chr 3:38,982,671...39,035,850
|
|
| G
|
Gsta2
|
glutathione S-transferase alpha 2
|
increases expression
|
EXP
|
Medroxyprogesterone Acetate results in increased expression of GSTA2 mRNA
|
CTD |
PMID:11502894 |
|
NCBI chr 8:88,064,829...88,077,168
Ensembl chr 8:88,064,616...88,077,092
|
|
| G
|
Gstm5
|
glutathione S-transferase, mu 5
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of GSTM3 mRNA
|
CTD |
PMID:18497975 |
|
NCBI chr 2:198,219,769...198,222,732
Ensembl chr 2:198,219,647...198,222,731
|
|
| G
|
Havcr2
|
hepatitis A virus cellular receptor 2
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of HAVCR2 mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr10:30,882,484...30,914,018
Ensembl chr10:31,383,925...31,413,872
|
|
| G
|
Hbegf
|
heparin-binding EGF-like growth factor
|
decreases expression
|
ISO
|
Medroxyprogesterone Acetate results in decreased expression of HBEGF mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr18:28,380,337...28,390,220
Ensembl chr18:28,380,337...28,390,220
|
|
| G
|
Hoxa1
|
homeobox A1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of HOXA1 mRNA; Azacitidine inhibits the reaction [[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of HOXA1 mRNA]
|
CTD |
PMID:20823114 |
|
NCBI chr 4:82,586,505...82,589,209
Ensembl chr 4:82,586,505...82,589,209
|
|
| G
|
Hoxa10
|
homeobox A10
|
multiple interactions increases expression
|
ISO
|
[Medroxyprogesterone Acetate co-treated with Estrogens] results in increased expression of HOXA10 mRNA; Mifepristone inhibits the reaction [Medroxyprogesterone Acetate results in increased expression of HOXA10 mRNA]
|
CTD |
PMID:16632680 PMID:21670700 |
|
NCBI chr 4:81,331,591...81,340,878
Ensembl chr 4:82,662,204...82,665,922
|
|
| G
|
Hoxa11
|
homeobox A11
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of HOXA11 mRNA
|
CTD |
PMID:16632680 |
|
NCBI chr 4:81,342,527...81,346,189
Ensembl chr 4:82,673,140...82,676,844
|
|
| G
|
Hsd11b1
|
hydroxysteroid 11-beta dehydrogenase 1
|
multiple interactions
|
ISO
|
[Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of and results in increased activity of HSD11B1 protein; [Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of HSD11B1 mRNA
|
CTD |
PMID:23275455 |
|
NCBI chr13:107,277,526...107,327,462
Ensembl chr13:107,257,239...107,327,432
|
|
| G
|
Hsd11b2
|
hydroxysteroid 11-beta dehydrogenase 2
|
multiple interactions
|
ISO
|
[Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of HSD11B2 protein
|
CTD |
PMID:23275455 |
|
NCBI chr19:50,307,569...50,312,812
Ensembl chr19:50,307,569...50,312,812
|
|
| G
|
Hsd17b2
|
hydroxysteroid (17-beta) dehydrogenase 2
|
decreases expression
|
ISO
|
Medroxyprogesterone Acetate results in decreased expression of HSD17B2 mRNA
|
CTD |
PMID:23183084 |
|
NCBI chr19:45,753,576...45,825,203
Ensembl chr19:62,662,098...62,733,943
|
|
| G
|
Htr1a
|
5-hydroxytryptamine receptor 1A
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of HTR1A mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 2:36,693,462...36,698,026
Ensembl chr 2:38,427,083...38,540,760
|
|
| G
|
Icam1
|
intercellular adhesion molecule 1
|
multiple interactions
|
ISO
|
Medroxyprogesterone Acetate inhibits the reaction [Hydrocortisone inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 protein]]; Medroxyprogesterone Acetate inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 protein]; Mifepristone inhibits the reaction [Medroxyprogesterone Acetate inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 protein]]
|
CTD |
PMID:15358673 |
|
NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:27,829,161...27,841,617
|
|
| G
|
Idh1
|
isocitrate dehydrogenase (NADP(+)) 1
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of IDH1 mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr 9:74,027,887...74,057,442
Ensembl chr 9:74,027,892...74,049,555
|
|
| G
|
Ido1
|
indoleamine 2,3-dioxygenase 1
|
multiple interactions
|
ISO
|
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[IFNG protein co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of IDO1 mRNA]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[IFNG protein co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of IDO1 protein]; [IFNG protein co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of IDO1 mRNA; [IFNG protein co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of IDO1 protein
|
CTD |
PMID:32781018 |
|
NCBI chr16:67,430,654...67,442,726
Ensembl chr16:74,133,259...74,145,328
|
|
| G
|
Ifng
|
interferon gamma
|
multiple interactions
|
ISO
|
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[IFNG protein co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased abundance of Kynurenine]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[IFNG protein co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of AHR mRNA]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[IFNG protein co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of CYP1A1 mRNA]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[IFNG protein co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of CYP1B1 mRNA]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[IFNG protein co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of IDO1 mRNA]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[IFNG protein co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of IDO1 protein]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[IFNG protein co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of TDO2 mRNA]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [IFNG protein promotes the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of IGFBP1 mRNA]]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [IFNG protein promotes the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of PRL mRNA]]; [Estrogens, Conjugated (USP) co-treated with Medroxyprogesterone Acetate] results in decreased secretion of IFNG protein; [IFNG protein co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased abundance of Kynurenine; [IFNG protein co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of AHR mRNA; [IFNG protein co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of CYP1A1 mRNA; [IFNG protein co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of CYP1B1 mRNA; [IFNG protein co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of IDO1 mRNA; [IFNG protein co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of IDO1 protein; [IFNG protein co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of TDO2 mRNA; IFNG protein promotes the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of IGFBP1 mRNA]; IFNG protein promotes the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of PRL mRNA]; IFNG protein promotes the reaction [Tryptophan promotes the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of IGFBP1 mRNA]]; IFNG protein promotes the reaction [Tryptophan promotes the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of PRL mRNA]]
|
CTD |
PMID:16236362 PMID:32781018 |
|
NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216
|
|
| G
|
Ifrd2
|
interferon-related developmental regulator 2
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of IFRD2 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 8:117,139,612...117,144,834
Ensembl chr 8:117,139,550...117,144,836
|
|
| G
|
Igfbp1
|
insulin-like growth factor binding protein 1
|
multiple interactions increases expression
|
ISO
|
2-hydroxyestradiol promotes the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of IGFBP1 mRNA]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of IGFBP1 mRNA]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [IFNG protein promotes the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of IGFBP1 mRNA]]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Kynurenine promotes the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of IGFBP1 mRNA]]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Tryptophan promotes the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of IGFBP1 mRNA]]; 4-hydroxyestradiol promotes the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of IGFBP1 mRNA]; [8-Bromo Cyclic Adenosine Monophosphate co-treated with Medroxyprogesterone Acetate] results in increased expression of IGFBP1 mRNA; [Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of IGFBP1 mRNA; [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of IGFBP1 mRNA; [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of IGFBP1 protein; [Estradiol co-treated with Medroxyprogesterone Acetate] results in increased expression of IGFBP1; [Estradiol co-treated with Medroxyprogesterone Acetate] results in increased expression of IGFBP1 mRNA; [Estradiol deficiency co-treated with Medroxyprogesterone Acetate deficiency] results in decreased expression of IGFBP1 mRNA; [Estradiol deficiency co-treated with Medroxyprogesterone Acetate deficiency] results in increased expression of IGFBP1 mRNA; [Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased secretion of IGFBP1 protein; [Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of IGFBP1 mRNA; [Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of IGFBP1 protein; [Medroxyprogesterone Acetate co-treated with Estradiol co-treated with Colforsin] results in increased expression of IGFBP1 mRNA; Azacitidine inhibits the reaction [[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of IGFBP1 mRNA]; Azacitidine promotes the reaction [[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of IGFBP1 protein]; Cadmium inhibits the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of IGFBP1 mRNA]; Cadmium inhibits the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of IGFBP1 protein]; Cannabidiol inhibits the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of IGFBP1 mRNA]; Estradiol promotes the reaction [Medroxyprogesterone Acetate results in increased expression of IGFBP1 mRNA]; EZH2 mutant form inhibits the reaction [[8-Bromo Cyclic Adenosine Monophosphate co-treated with Medroxyprogesterone Acetate] results in increased expression of IGFBP1 mRNA]; FOXO1 protein affects the reaction [[Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased secretion of IGFBP1 protein]; IFNG protein promotes the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of IGFBP1 mRNA]; IFNG protein promotes the reaction [Tryptophan promotes the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of IGFBP1 mRNA]]; Kynurenine promotes the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of IGFBP1 mRNA]; NAD inhibits the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of IGFBP1 mRNA]; Tryptophan promotes the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of IGFBP1 mRNA]
|
CTD |
PMID:11756571 PMID:12093828 PMID:16709600 PMID:20685861 PMID:20823114 PMID:21903722 PMID:30328349 PMID:31154070 PMID:31953017 PMID:32781018 PMID:39892737 More...
|
|
NCBI chr14:86,261,277...86,266,344
Ensembl chr14:86,261,277...86,266,344
|
|
| G
|
Igfbp3
|
insulin-like growth factor binding protein 3
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of IGFBP3 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr14:86,270,208...86,277,944
Ensembl chr14:86,270,208...86,277,944
|
|
| G
|
Igfbp4
|
insulin-like growth factor binding protein 4
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of IGFBP4 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr10:84,491,471...84,503,487
Ensembl chr10:84,485,775...84,503,473
|
|
| G
|
Igfbp5
|
insulin-like growth factor binding protein 5
|
decreases expression
|
ISO
|
Medroxyprogesterone Acetate results in decreased expression of IGFBP5 mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr 9:81,901,605...81,914,187
Ensembl chr 9:81,897,616...81,914,390
|
|
| G
|
Il11
|
interleukin 11
|
decreases expression
|
ISO
|
Medroxyprogesterone Acetate results in decreased expression of IL11 mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr 1:78,098,622...78,104,915
Ensembl chr 1:78,096,930...78,104,915
|
|
| G
|
Il12b
|
interleukin 12B
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of IL12B mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr10:29,390,300...29,405,194
Ensembl chr10:29,389,905...29,405,194
|
|
| G
|
Il1b
|
interleukin 1 beta
|
multiple interactions decreases expression
|
ISO
|
[Indomethacin co-treated with Medroxyprogesterone Acetate] results in decreased secretion of IL1B protein Medroxyprogesterone Acetate results in decreased expression of IL1B mRNA
|
CTD |
PMID:16537180 PMID:20843944 |
|
NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
|
|
| G
|
Il2
|
interleukin 2
|
multiple interactions
|
ISO
|
[Estrogens, Conjugated (USP) co-treated with Medroxyprogesterone Acetate] results in decreased secretion of IL2 protein
|
CTD |
PMID:16236362 |
|
NCBI chr 2:121,932,968...121,937,672
Ensembl chr 2:121,932,968...121,937,672
|
|
| G
|
Il23a
|
interleukin 23 subunit alpha
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of IL23A mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 7:1,306,320...1,308,434
Ensembl chr 7:1,306,320...1,308,434
|
|
| G
|
Il24
|
interleukin 24
|
decreases expression
|
ISO
|
Medroxyprogesterone Acetate results in decreased expression of IL24 mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr13:44,905,362...44,910,760
Ensembl chr13:44,905,363...44,910,760
|
|
| G
|
Il6
|
interleukin 6
|
multiple interactions decreases expression decreases secretion
|
ISO
|
[Polyphenols co-treated with Antioxidants co-treated with Eicosapentaenoic Acid co-treated with Docosahexaenoic Acids co-treated with Medroxyprogesterone Acetate co-treated with Celecoxib] results in decreased expression of IL6 Medroxyprogesterone Acetate results in decreased expression of IL6 mRNA Medroxyprogesterone Acetate results in decreased secretion of IL6 protein [Indomethacin co-treated with Medroxyprogesterone Acetate] results in decreased secretion of IL6 protein
|
CTD |
PMID:16537180 PMID:16702388 PMID:20843944 |
|
NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
|
|
| G
|
Ints7
|
integrator complex subunit 7
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of INTS7 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr13:103,155,123...103,207,953
Ensembl chr13:105,686,128...105,739,608
|
|
| G
|
Irf9
|
interferon regulatory factor 9
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of IRF9 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr15:29,095,474...29,101,924
Ensembl chr15:33,065,659...33,071,879
|
|
| G
|
Irs2
|
insulin receptor substrate 2
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of IRS2 mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr16:85,190,310...85,214,543
Ensembl chr16:85,190,111...85,214,543
|
|
| G
|
Isg20l2
|
interferon stimulated exonuclease gene 20-like 2
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of ISG20L2 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 2:173,396,780...173,407,102
Ensembl chr 2:175,695,615...175,705,095
|
|
| G
|
Itga1
|
integrin subunit alpha 1
|
decreases expression
|
ISO
|
Medroxyprogesterone Acetate results in decreased expression of ITGA1 mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr 2:46,646,125...46,812,237
Ensembl chr 2:48,386,249...48,545,284
|
|
| G
|
Itga11
|
integrin subunit alpha 11
|
decreases expression
|
ISO
|
Medroxyprogesterone Acetate results in decreased expression of ITGA11 mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr 8:63,145,998...63,254,714
Ensembl chr 8:72,016,652...72,150,137
|
|
| G
|
Itga2
|
integrin subunit alpha 2
|
decreases expression
|
ISO
|
Medroxyprogesterone Acetate results in decreased expression of ITGA2 mRNA
|
CTD |
PMID:18497975 |
|
NCBI chr 2:48,253,412...48,354,509
Ensembl chr 2:48,253,412...48,354,509
|
|
| G
|
Itgb1
|
integrin subunit beta 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of ITGB1 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr19:73,602,277...73,650,271
Ensembl chr19:73,602,126...73,650,269
|
|
| G
|
Itgb5
|
integrin subunit beta 5
|
decreases expression
|
ISO
|
Medroxyprogesterone Acetate results in decreased expression of ITGB5 mRNA
|
CTD |
PMID:18497975 |
|
NCBI chr11:66,828,428...66,944,231
Ensembl chr11:80,333,590...80,449,373
|
|
| G
|
Itih5
|
inter-alpha-trypsin inhibitor heavy chain 5
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of ITIH5 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr17:73,161,886...73,261,930
Ensembl chr17:73,161,611...73,262,496
|
|
| G
|
Kcnb1
|
potassium voltage-gated channel subfamily B member 1
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of KCNB1 mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr 3:155,820,255...155,913,383
Ensembl chr 3:176,242,589...176,332,408
|
|
| G
|
Kcnc4
|
potassium voltage-gated channel subfamily C member 4
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of KCNC4 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 2:195,063,967...195,100,244
Ensembl chr 2:197,759,010...197,788,433
|
|
| G
|
Kdr
|
kinase insert domain receptor
|
decreases expression
|
ISO
|
Medroxyprogesterone Acetate results in decreased expression of KDR mRNA
|
CTD |
PMID:18497975 |
|
NCBI chr14:32,572,031...32,615,204
Ensembl chr14:32,572,049...32,615,192
|
|
| G
|
Klf4
|
KLF transcription factor 4
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of KLF4 mRNA
|
CTD |
PMID:18497975 |
|
NCBI chr 5:75,074,107...75,079,182
Ensembl chr 5:75,074,236...75,078,592
|
|
| G
|
Krt8
|
keratin 8
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of KRT8 mRNA; Azacitidine inhibits the reaction [[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of KRT8 mRNA]
|
CTD |
PMID:20823114 |
|
NCBI chr 7:135,002,886...135,010,339
Ensembl chr 7:135,002,894...135,010,403
|
|
| G
|
Lama4
|
laminin subunit alpha 4
|
decreases expression
|
ISO
|
Medroxyprogesterone Acetate results in decreased expression of LAMA4 mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr20:42,392,268...42,533,347
Ensembl chr20:43,946,898...44,087,972
|
|
| G
|
Lamb2
|
laminin subunit beta 2
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of LAMB2 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 8:109,178,367...109,190,552
Ensembl chr 8:118,056,935...118,069,090
|
|
| G
|
Lcn2
|
lipocalin 2
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Medroxyprogesterone Acetate] results in decreased expression of LCN2 mRNA
|
CTD |
PMID:15866426 |
|
NCBI chr 3:36,078,432...36,081,851
Ensembl chr 3:36,078,436...36,081,842
|
|
| G
|
Ldha
|
lactate dehydrogenase A
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of LDHA mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 1:106,508,092...106,517,512
Ensembl chr 1:106,502,182...106,517,521
|
|
| G
|
Lgals3
|
galectin 3
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of LGALS3 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr15:23,099,795...23,111,731
Ensembl chr15:23,086,841...23,111,737
|
|
| G
|
LOC120095955
|
mucin-12-like
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of MUC12 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr12:19,486,041...19,493,995
|
|
| G
|
Loxl4
|
lysyl oxidase-like 4
|
decreases expression
|
ISO
|
Medroxyprogesterone Acetate results in decreased expression of LOXL4 mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr 1:251,345,445...251,365,640
Ensembl chr 1:251,347,238...251,365,577
|
|
| G
|
Lpar3
|
lysophosphatidic acid receptor 3
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of LPAR3 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 2:237,785,371...237,854,199
Ensembl chr 2:237,787,766...237,854,197
|
|
| G
|
Lratd2
|
LRAT domain containing 2
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of LRATD2 mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr 7:92,376,713...92,387,045
Ensembl chr 7:94,073,513...94,277,046
|
|
| G
|
Ltbp1
|
latent transforming growth factor beta binding protein 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of LTBP1 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 6:20,029,629...20,425,339
Ensembl chr 6:25,781,638...26,454,036
|
|
| G
|
Lyve1
|
lymphatic vessel endothelial hyaluronan receptor 1
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of XLKD1 mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr 1:174,393,387...174,410,977
|
|
| G
|
Map1a
|
microtubule-associated protein 1A
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of MAP1A mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 3:128,716,907...128,736,638
Ensembl chr 3:128,716,940...128,740,159
|
|
| G
|
Map4k4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of MAP4K4 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 9:49,696,573...49,822,353
Ensembl chr 9:49,696,700...49,822,353
|
|
| G
|
Map7
|
microtubule-associated protein 7
|
decreases expression
|
ISO
|
Medroxyprogesterone Acetate results in decreased expression of MAP7 mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr 1:14,910,433...15,037,574
Ensembl chr 1:16,730,075...16,857,170
|
|
| G
|
Mapk1
|
mitogen activated protein kinase 1
|
multiple interactions
|
ISO
|
Medroxyprogesterone Acetate results in increased phosphorylation of and results in increased activity of MAPK1 protein
|
CTD |
PMID:20535544 |
|
NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825
|
|
| G
|
Mapk3
|
mitogen activated protein kinase 3
|
multiple interactions
|
ISO
|
Medroxyprogesterone Acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein
|
CTD |
PMID:20535544 |
|
NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411
|
|
| G
|
Marco
|
macrophage receptor with collagenous structure
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of MARCO mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr13:31,616,278...31,648,521
Ensembl chr13:34,169,011...34,201,255
|
|
| G
|
Mgat4b
|
alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of MGAT4B mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr10:34,548,918...34,559,229
Ensembl chr10:35,050,512...35,060,309
|
|
| G
|
Mgst1
|
microsomal glutathione S-transferase 1
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of MGST1 mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr 4:172,760,930...172,776,157
Ensembl chr 4:172,760,886...172,776,875
|
|
| G
|
Mir142
|
microRNA 142
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of MIR142 mRNA
|
CTD |
PMID:22543862 |
|
NCBI chr10:72,557,864...72,557,950
Ensembl chr10:73,055,097...73,055,207
|
|
| G
|
Mir146b
|
microRNA 146b
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of MIR146B mRNA
|
CTD |
PMID:22543862 |
|
NCBI chr 1:245,203,438...245,203,525
Ensembl chr 1:255,144,860...255,144,947
|
|
| G
|
Mir193b
|
microRNA 193b
|
decreases expression
|
ISO
|
Medroxyprogesterone Acetate results in decreased expression of MIR193B mRNA
|
CTD |
PMID:22543862 |
|
NCBI chr10:1,317,742...1,317,824
Ensembl chr10:1,824,944...1,825,026
|
|
| G
|
Mir21
|
microRNA 21
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of MIR21 mRNA
|
CTD |
PMID:22543862 |
|
NCBI chr10:71,902,600...71,902,691
|
|
| G
|
Mir27b
|
microRNA 27b
|
multiple interactions
|
ISO
|
[Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of MIR27B mRNA
|
CTD |
PMID:30328349 |
|
NCBI chr17:1,819,147...1,819,243
|
|
| G
|
Mmp1
|
matrix metallopeptidase 1
|
decreases expression
|
ISO
|
Medroxyprogesterone Acetate results in decreased expression of MMP1 mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:12,943,453...12,963,964
|
|
| G
|
Mmp2
|
matrix metallopeptidase 2
|
multiple interactions decreases activity
|
ISO
|
[Indomethacin co-treated with Medroxyprogesterone Acetate] results in decreased activity of MMP2 protein [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of MMP2 mRNA Medroxyprogesterone Acetate results in decreased activity of MMP2 protein
|
CTD |
PMID:16537180 PMID:20823114 |
|
NCBI chr19:30,327,643...30,355,856
Ensembl chr19:30,327,643...30,355,856
|
|
| G
|
Mmp9
|
matrix metallopeptidase 9
|
multiple interactions decreases expression decreases activity
|
ISO
|
[Indomethacin co-treated with Medroxyprogesterone Acetate] results in decreased activity of MMP9 protein Medroxyprogesterone Acetate results in decreased expression of MMP9 mRNA Medroxyprogesterone Acetate results in decreased activity of MMP9 protein
|
CTD |
PMID:16537180 PMID:20843944 |
|
NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442
|
|
| G
|
Mmrn1
|
multimerin 1
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of MMRN1 mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr 4:89,875,408...89,950,814
Ensembl chr 4:91,233,240...91,280,861
|
|
| G
|
Ms4a6a
|
membrane spanning 4-domains A6A
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of MS4A6A mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr 1:217,826,261...217,839,606
Ensembl chr 1:217,826,261...217,850,013
|
|
| G
|
Mthfd2
|
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of MTHFD2 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 4:117,368,833...117,380,350
Ensembl chr 4:117,368,835...117,380,350
|
|
| G
|
Mtr
|
5-methyltetrahydrofolate-homocysteine methyltransferase
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of MTR mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr17:62,911,705...62,996,544
Ensembl chr17:62,911,771...62,996,541
|
|
| G
|
Mtss1
|
MTSS I-BAR domain containing 1
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of MTSS1 mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr 7:92,378,228...92,517,444
Ensembl chr 7:92,378,238...92,517,303
|
|
| G
|
Muc1
|
mucin 1, cell surface associated
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of MUC1 mRNA
|
CTD |
PMID:18497975 |
|
NCBI chr 2:174,635,989...174,640,738
Ensembl chr 2:176,933,047...176,938,491
|
|
| G
|
Myb
|
MYB proto-oncogene, transcription factor
|
decreases expression
|
ISO
|
Medroxyprogesterone Acetate results in decreased expression of MYB mRNA
|
CTD |
PMID:18497975 |
|
NCBI chr 1:15,939,771...15,973,367
Ensembl chr 1:17,759,309...17,792,547
|
|
| G
|
Myh9
|
myosin, heavy chain 9
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of MYH9 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 7:111,224,291...111,304,963
Ensembl chr 7:111,224,291...111,304,963
|
|
| G
|
Myl12a
|
myosin light chain 12A
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of MYL12A mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 9:110,891,970...110,899,655
Ensembl chr 9:118,338,604...118,342,634
|
|
| G
|
Myl12b
|
myosin light chain 12B
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of MYL12B mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 9:118,320,479...118,334,810
Ensembl chr 9:118,320,489...118,324,418
|
|
| G
|
Mylk
|
myosin light chain kinase
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of MYLK mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr11:65,783,008...66,030,239
Ensembl chr11:79,288,243...79,535,659
|
|
| G
|
Myof
|
myoferlin
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of MYOF mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 1:245,086,109...245,234,768
Ensembl chr 1:245,086,109...245,234,768
|
|
| G
|
Ncf1
|
neutrophil cytosolic factor 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of NCF1 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr12:28,121,816...28,131,080
Ensembl chr12:28,121,366...28,131,079
|
|
| G
|
Ncf2
|
neutrophil cytosolic factor 2
|
multiple interactions
|
EXP
|
[Medroxyprogesterone Acetate co-treated with Estradiol] results in increased expression of NCF2 protein
|
CTD |
PMID:21670166 |
|
NCBI chr13:67,505,492...67,536,015
Ensembl chr13:67,505,375...67,536,149
|
|
| G
|
Ncoa1
|
nuclear receptor coactivator 1
|
multiple interactions
|
ISO
|
Medroxyprogesterone Acetate promotes the reaction [PGR protein binds to NCOA1 protein]
|
CTD |
PMID:15937332 |
|
NCBI chr 6:32,952,090...33,229,829
Ensembl chr 6:32,952,090...33,195,924
|
|
| G
|
Ndst1
|
N-deacetylase and N-sulfotransferase 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of NDST1 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr18:56,407,308...56,470,007
Ensembl chr18:56,411,200...56,448,612
|
|
| G
|
Nefm
|
neurofilament medium chain
|
decreases expression
|
ISO
|
Medroxyprogesterone Acetate results in decreased expression of NEFM mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr15:46,535,857...46,541,161
Ensembl chr15:46,535,517...46,541,163
|
|
| G
|
Nexn
|
nexilin (F actin binding protein)
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of NEXN mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 2:241,186,783...241,218,315
Ensembl chr 2:243,846,433...243,887,114
|
|
| G
|
Nfe2l2
|
NFE2 like bZIP transcription factor 2
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of NFE2L2 mRNA
|
CTD |
PMID:18497975 |
|
NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090
|
|
| G
|
Nom1
|
nucleolar protein with MIF4G domain 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of NOM1 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 4:6,562,931...6,586,093
Ensembl chr 4:6,567,836...6,585,036
|
|
| G
|
Nos3
|
nitric oxide synthase 3
|
multiple interactions
|
ISO EXP
|
Medroxyprogesterone Acetate inhibits the reaction [Estradiol results in increased activity of NOS3 protein]; Medroxyprogesterone Acetate inhibits the reaction [Estradiol results in increased expression of NOS3 protein]
|
CTD |
PMID:15358673 |
|
NCBI chr 4:11,686,088...11,706,604
Ensembl chr 4:11,686,268...11,706,664
|
|
| G
|
Nphp1
|
nephrocystin 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of NPHP1 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 3:114,960,650...115,016,234
Ensembl chr 3:135,413,927...135,469,505
|
|
| G
|
Nptx2
|
neuronal pentraxin 2
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of NPTX2 mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr12:10,037,435...10,048,345
Ensembl chr12:15,151,136...15,162,045
|
|
| G
|
Nptxr
|
neuronal pentraxin receptor
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of NPTXR mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 7:113,217,046...113,235,122
Ensembl chr 7:113,217,050...113,235,156
|
|
| G
|
Npy1r
|
neuropeptide Y receptor Y1
|
multiple interactions decreases expression
|
ISO
|
Medroxyprogesterone Acetate inhibits the reaction [Estradiol results in increased expression of NPY1R mRNA] Medroxyprogesterone Acetate results in decreased expression of NPY1R mRNA
|
CTD |
PMID:18497975 PMID:19146866 |
|
NCBI chr16:27,804,416...27,814,070
Ensembl chr16:27,804,416...27,813,387
|
|
| G
|
Nr1i2
|
nuclear receptor subfamily 1, group I, member 2
|
increases activity
|
ISO
|
Medroxyprogesterone Acetate results in increased activity of NR1I2 protein
|
CTD |
PMID:15650019 |
|
NCBI chr11:75,965,717...76,006,733
Ensembl chr11:75,965,632...76,002,380
|
|
| G
|
Nr2f1
|
nuclear receptor subfamily 2, group F, member 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of NR2F1 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 2:8,040,375...8,050,123
Ensembl chr 2:9,776,179...9,785,924
|
|
| G
|
Nr3c1
|
nuclear receptor subfamily 3, group C, member 1
|
affects response to substance multiple interactions
|
ISO
|
NR3C1 protein affects the susceptibility to Medroxyprogesterone Acetate [Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in decreased expression of NR3C1 mRNA; [Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in decreased expression of NR3C1 protein
|
CTD |
PMID:23275455 PMID:23658782 |
|
NCBI chr18:31,522,783...31,644,508
Ensembl chr18:31,522,783...31,643,843
|
|
| G
|
Nr3c2
|
nuclear receptor subfamily 3, group C, member 2
|
multiple interactions
|
ISO
|
[Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of NR3C2 mRNA; [Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of NR3C2 protein
|
CTD |
PMID:23275455 |
|
NCBI chr19:47,619,853...47,964,089
Ensembl chr19:47,619,853...47,964,078
|
|
| G
|
Nr4a2
|
nuclear receptor subfamily 4, group A, member 2
|
decreases expression
|
ISO
|
Medroxyprogesterone Acetate results in decreased expression of NR4A2 mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr 3:62,098,739...62,115,926
Ensembl chr 3:62,098,743...62,106,769
|
|
| G
|
Nrip1
|
nuclear receptor interacting protein 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of NRIP1 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr11:14,895,843...14,979,490
Ensembl chr11:28,378,878...28,467,353
|
|
| G
|
Nt5e
|
5' nucleotidase, ecto
|
decreases expression multiple interactions
|
ISO
|
Medroxyprogesterone Acetate results in decreased expression of NT5E mRNA [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of NT5E mRNA
|
CTD |
PMID:20823114 PMID:20843944 |
|
NCBI chr 8:89,271,046...89,314,918
Ensembl chr 8:98,150,900...98,195,645
|
|
| G
|
Nts
|
neurotensin
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of NTS mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 7:39,451,484...39,460,888
Ensembl chr 7:39,451,073...39,460,961
|
|
| G
|
Nup155
|
nucleoporin 155
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of NUP155 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 2:57,201,310...57,252,918
Ensembl chr 2:58,928,537...58,981,242
|
|
| G
|
Ogfrl1
|
opioid growth factor receptor-like 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of OGFRL1 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 9:25,828,865...25,842,424
Ensembl chr 9:33,324,392...33,339,237
|
|
| G
|
Or8b8
|
olfactory receptor family 8 subfamily B member 8
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of OR8B8 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 8:37,693,578...37,694,510
Ensembl chr 8:45,882,321...45,883,253
|
|
| G
|
P4hb
|
prolyl 4-hydroxylase subunit beta
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of P4HB mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr10:105,836,972...105,848,583
Ensembl chr10:106,335,300...106,346,911
|
|
| G
|
Paep
|
progestagen associated endometrial protein
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of PAEP mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 3:8,531,136...8,534,430
|
|
| G
|
Pakap
|
paralemmin A kinase anchor protein
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of PALM2AKAP2 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 5:76,976,906...77,443,656
Ensembl chr 5:76,977,112...77,443,656
|
|
| G
|
Pcdh17
|
protocadherin 17
|
decreases expression
|
ISO
|
Medroxyprogesterone Acetate results in decreased expression of PCDH17 mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr15:66,631,549...66,725,007
Ensembl chr15:66,633,142...66,722,105
|
|
| G
|
Pcdh18
|
protocadherin 18
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of PCDH18 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 2:135,982,929...135,996,917
Ensembl chr 2:135,983,144...135,996,826
|
|
| G
|
Pcdh20
|
protocadherin 20
|
decreases expression
|
ISO
|
Medroxyprogesterone Acetate results in decreased expression of PCDH20 mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr15:64,425,534...64,431,790
Ensembl chr15:70,834,042...70,840,298
|
|
| G
|
Pcdhb5
|
protocadherin beta 5
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of PCDHB4 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr18:29,302,466...29,305,048
|
|
| G
|
Pdgfa
|
platelet derived growth factor subunit A
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Medroxyprogesterone Acetate] results in decreased secretion of [PDGFA protein binds to PDGFB protein]
|
CTD |
PMID:15866426 |
|
NCBI chr12:15,645,549...15,667,056
Ensembl chr12:20,754,208...20,780,322
|
|
| G
|
Pdgfb
|
platelet derived growth factor subunit B
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Medroxyprogesterone Acetate] results in decreased secretion of [PDGFA protein binds to PDGFB protein]
|
CTD |
PMID:15866426 |
|
NCBI chr 7:113,419,882...113,438,343
Ensembl chr 7:113,420,710...113,438,343
|
|
| G
|
Pdk1
|
pyruvate dehydrogenase kinase 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of PDK1 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 3:77,113,464...77,144,145
Ensembl chr 3:77,113,473...77,144,145
|
|
| G
|
Penk
|
proenkephalin
|
decreases expression
|
ISO
|
Medroxyprogesterone Acetate results in decreased expression of PENK mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr 5:21,981,381...21,987,074
Ensembl chr 5:21,981,382...21,986,705
|
|
| G
|
Pgr
|
progesterone receptor
|
decreases expression multiple interactions
|
ISO
|
Medroxyprogesterone Acetate results in decreased expression of PGR protein Medroxyprogesterone Acetate results in decreased expression of PGR mRNA; Medroxyprogesterone Acetate results in decreased expression of PGR protein [Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of PGR mRNA; Cadmium inhibits the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of PGR mRNA]; Medroxyprogesterone Acetate promotes the reaction [PGR protein binds to NCOA1 protein]
|
CTD |
PMID:2151368 PMID:15937332 PMID:20843944 PMID:23183084 PMID:39892737 |
|
NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:14,354,398...14,413,271
|
|
| G
|
Pgrmc2
|
progesterone receptor membrane component 2
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of PGRMC2 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 2:125,996,190...126,012,090
Ensembl chr 2:125,996,193...126,012,090
|
|
| G
|
Pitpnc1
|
phosphatidylinositol transfer protein, cytoplasmic 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of PITPNC1 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr10:92,663,260...92,928,616
Ensembl chr10:92,663,260...92,928,344
|
|
| G
|
Pkd2l1
|
polycystin 2 like 1, transient receptor potential cation channel
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of PKD2L1 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 1:252,982,096...253,019,235
Ensembl chr 1:252,982,096...253,023,359
|
|
| G
|
Plat
|
plasminogen activator, tissue type
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of PLAT mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr16:75,943,061...76,022,037
Ensembl chr16:75,943,064...75,967,696
|
|
| G
|
Plau
|
plasminogen activator, urokinase
|
decreases expression
|
ISO
|
Medroxyprogesterone Acetate results in decreased expression of PLAU mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr15:3,505,485...3,511,987
Ensembl chr15:3,505,487...3,512,030
|
|
| G
|
Plcxd3
|
phosphatidylinositol-specific phospholipase C, X domain containing 3
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of PLCXD3 mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr 2:53,567,022...53,746,384
Ensembl chr 2:55,294,613...55,474,220
|
|
| G
|
Plekhg3
|
pleckstrin homology and RhoGEF domain containing G3
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of PLEKHG3 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 6:100,998,965...101,042,120
Ensembl chr 6:100,994,417...101,042,118
|
|
| G
|
Plg
|
plasminogen
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of PLG
|
CTD |
PMID:1828463 |
|
NCBI chr 1:50,872,927...50,915,406
Ensembl chr 1:50,872,926...50,917,320
|
|
| G
|
Plod2
|
procollagen lysine, 2-oxoglutarate 5-dioxygenase 2
|
decreases expression
|
ISO
|
Medroxyprogesterone Acetate results in decreased expression of PLOD2 mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr 8:101,964,318...102,047,022
Ensembl chr 8:101,964,318...102,047,022
|
|
| G
|
Pls3
|
plastin 3
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of PLS3 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr X:116,401,247...116,495,898
Ensembl chr X:116,401,293...116,495,893
|
|
| G
|
Ppbp
|
pro-platelet basic protein
|
decreases expression
|
ISO
|
Medroxyprogesterone Acetate results in decreased expression of PPBP mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr14:17,586,495...17,587,299
Ensembl chr14:17,586,495...17,587,299
|
|
| G
|
Ppia
|
peptidylprolyl isomerase A
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of PPIA mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr14:81,279,292...81,282,960
Ensembl chr14:85,492,484...85,497,115
|
|
| G
|
Prdx5
|
peroxiredoxin 5
|
affects expression multiple interactions
|
EXP
|
Medroxyprogesterone Acetate affects the expression of PRDX5 [Medroxyprogesterone Acetate co-treated with Estradiol] affects the expression of PRDX5
|
CTD |
PMID:21159850 |
|
NCBI chr 1:213,529,042...213,532,787
Ensembl chr 1:213,529,035...213,533,020
|
|
| G
|
Prl
|
prolactin
|
multiple interactions increases expression
|
ISO
|
2-hydroxyestradiol promotes the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of PRL mRNA]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of PRL mRNA]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [IFNG protein promotes the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of PRL mRNA]]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Kynurenine promotes the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of PRL mRNA]]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Tryptophan promotes the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of PRL mRNA]]; 4-hydroxyestradiol promotes the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of PRL mRNA]; [8-Bromo Cyclic Adenosine Monophosphate co-treated with Medroxyprogesterone Acetate] results in increased expression of PRL mRNA; [Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of PRL mRNA; [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate co-treated with Azacitidine] results in increased expression of PRL mRNA; [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate co-treated with Azacitidine] results in increased expression of PRL protein; [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of PRL mRNA; [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of PRL protein; [Estradiol co-treated with Medroxyprogesterone Acetate] results in increased expression of PRL mRNA; [Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased secretion of PRL protein; [Medroxyprogesterone Acetate co-treated with Bucladesine] results in increased secretion of PRL protein; [Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of PRL mRNA; [Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of PRL protein; [Medroxyprogesterone Acetate co-treated with Estradiol co-treated with Colforsin] results in increased expression of PRL mRNA; [Medroxyprogesterone Acetate co-treated with Estradiol co-treated with Colforsin] results in increased secretion of PRL protein; AGT protein promotes the reaction [[Medroxyprogesterone Acetate co-treated with Bucladesine] results in increased secretion of PRL protein]; Cadmium inhibits the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of PRL mRNA]; Cadmium inhibits the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of PRL protein]; Cannabidiol inhibits the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of PRL mRNA]; Cannabidiol inhibits the reaction [[Medroxyprogesterone Acetate co-treated with Estradiol co-treated with Colforsin] results in increased expression of PRL mRNA]; Cannabidiol inhibits the reaction [[Medroxyprogesterone Acetate co-treated with Estradiol co-treated with Colforsin] results in increased secretion of PRL protein]; Cannabinol inhibits the reaction [[Medroxyprogesterone Acetate co-treated with Estradiol co-treated with Colforsin] results in increased expression of PRL mRNA]; Cannabinol inhibits the reaction [[Medroxyprogesterone Acetate co-treated with Estradiol co-treated with Colforsin] results in increased secretion of PRL protein]; Dinoprostone promotes the reaction [[Estradiol co-treated with Medroxyprogesterone Acetate] results in increased expression of PRL mRNA]; Dronabinol inhibits the reaction [[Medroxyprogesterone Acetate co-treated with Estradiol co-treated with Colforsin] results in increased expression of PRL mRNA]; Dronabinol inhibits the reaction [[Medroxyprogesterone Acetate co-treated with Estradiol co-treated with Colforsin] results in increased secretion of PRL protein]; EZH2 mutant form inhibits the reaction [[8-Bromo Cyclic Adenosine Monophosphate co-treated with Medroxyprogesterone Acetate] results in increased expression of PRL mRNA]; FOXO1 protein affects the reaction [[Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased secretion of PRL protein]; IFNG protein promotes the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of PRL mRNA]; IFNG protein promotes the reaction [Tryptophan promotes the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of PRL mRNA]]; Kynurenine promotes the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of PRL mRNA]; Losartan inhibits the reaction [AGT protein promotes the reaction [[Medroxyprogesterone Acetate co-treated with Bucladesine] results in increased secretion of PRL protein]]; Mifepristone inhibits the reaction [Medroxyprogesterone Acetate results in increased expression of PRL mRNA]; Rimonabant inhibits the reaction [Dronabinol inhibits the reaction [[Medroxyprogesterone Acetate co-treated with Estradiol co-treated with Colforsin] results in increased expression of PRL mRNA]]; Tryptophan promotes the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of PRL mRNA]
|
CTD |
PMID:7506205 PMID:15774544 PMID:16709600 PMID:20823114 PMID:21903722 PMID:30328349 PMID:31154070 PMID:31953017 PMID:32781018 PMID:36682589 PMID:39892737 More...
|
|
NCBI chr17:38,287,355...38,298,234
Ensembl chr17:38,288,162...38,298,217
|
|
| G
|
Prl8a2
|
prolactin family 8, subfamily A, member 2
|
multiple interactions
|
EXP
|
[Medroxyprogesterone Acetate co-treated with Bucladesine] results in increased expression of PRL8A2 mRNA
|
CTD |
PMID:19089455 |
|
NCBI chr17:37,613,263...37,622,288
Ensembl chr17:37,821,651...37,830,676
|
|
| G
|
Prrx1
|
paired related homeobox 1
|
decreases expression
|
ISO
|
Medroxyprogesterone Acetate results in decreased expression of PRRX1 mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr13:78,136,783...78,205,379
Ensembl chr13:78,136,783...78,204,058
|
|
| G
|
Prss12
|
serine protease 12
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of PRSS12 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 2:214,308,695...214,368,679
Ensembl chr 2:214,308,774...214,369,941
|
|
| G
|
Ptgs2
|
prostaglandin-endoperoxide synthase 2
|
decreases expression
|
ISO
|
Medroxyprogesterone Acetate results in decreased expression of PTGS2 mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320
|
|
| G
|
Ptk7
|
protein tyrosine kinase 7
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of PTK7 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 9:14,352,155...14,418,473
Ensembl chr 9:21,849,801...21,916,078
|
|
| G
|
Ptp4a1
|
protein tyrosine phosphatase 4A1
|
multiple interactions
|
ISO
|
Cycloheximide inhibits the reaction [Medroxyprogesterone Acetate inhibits the reaction [Estradiol results in increased expression of PTP4A1 mRNA]]; Medroxyprogesterone Acetate inhibits the reaction [Estradiol results in increased expression of PTP4A1 mRNA]
|
CTD |
PMID:19146866 |
|
NCBI chr 9:40,710,250...40,718,176
Ensembl chr 9:40,710,250...40,718,176
|
|
| G
|
Ptpa
|
protein phosphatase 2 phosphatase activator
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of PTPA mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 3:13,689,742...13,720,287
Ensembl chr 3:34,087,575...34,162,772
|
|
| G
|
Rab1b
|
RAB1B, member RAS oncogene family
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of RAB1B mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 1:211,835,133...211,843,408
Ensembl chr 1:211,835,073...211,843,337 Ensembl chr X:211,835,073...211,843,337
|
|
| G
|
Rab31
|
RAB31, member RAS oncogene family
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of RAB31 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 9:112,693,596...112,828,104
Ensembl chr 9:112,693,597...112,828,092
|
|
| G
|
Ran
|
RAN, member RAS oncogene family
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of RAN mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr12:33,311,155...33,314,339
Ensembl chr12:33,311,158...33,314,317
|
|
| G
|
Rela
|
RELA proto-oncogene, NF-kB subunit
|
multiple interactions
|
ISO
|
Medroxyprogesterone Acetate inhibits the reaction [Hydrocortisone inhibits the reaction [Lipopolysaccharides affects the localization of RELA protein]]; Medroxyprogesterone Acetate inhibits the reaction [Lipopolysaccharides affects the localization of RELA protein]; Mifepristone inhibits the reaction [Medroxyprogesterone Acetate inhibits the reaction [Lipopolysaccharides affects the localization of RELA protein]]
|
CTD |
PMID:15358673 |
|
NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817
|
|
| G
|
Ret
|
ret proto-oncogene
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of RET mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 4:151,325,969...151,368,176
Ensembl chr 4:152,998,812...153,040,556
|
|
| G
|
Rgs10
|
regulator of G-protein signaling 10
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of RGS10 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 1:192,376,772...192,422,640
Ensembl chr 1:192,376,774...192,418,904
|
|
| G
|
Rhobtb3
|
Rho-related BTB domain containing 3
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of RHOBTB3 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 2:7,094,972...7,201,507
Ensembl chr 2:7,095,253...7,150,906
|
|
| G
|
Rin1
|
Ras and Rab interactor 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of RIN1 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 1:202,355,729...202,362,731
Ensembl chr 1:211,784,943...211,791,368
|
|
| G
|
Rnase1
|
ribonuclease A family member 1, pancreatic
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of RNASE1 mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr15:24,361,924...24,363,633
Ensembl chr15:26,835,463...26,837,248
|
|
| G
|
Rpgr
|
retinitis pigmentosa GTPase regulator
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of RPGR mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr X:15,238,961...15,299,004
Ensembl chr X:15,239,159...15,298,999
|
|
| G
|
Rpn1
|
ribophorin I
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of RPN1 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 4:120,543,667...120,565,069
Ensembl chr 4:122,100,813...122,122,382
|
|
| G
|
Rps6kb1
|
ribosomal protein S6 kinase B1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of RPS6KB1 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr10:71,817,794...71,865,211
Ensembl chr10:71,815,614...71,865,238
|
|
| G
|
Rpsa
|
ribosomal protein SA
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of RPSA mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 8:119,851,225...119,855,103
Ensembl chr 8:128,728,862...128,732,737
|
|
| G
|
Runx1
|
RUNX family transcription factor 1
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of RUNX1 mRNA
|
CTD |
PMID:18497975 |
|
NCBI chr11:45,325,778...45,560,300
Ensembl chr11:45,329,044...45,564,925
|
|
| G
|
S100a14
|
S100 calcium binding protein A14
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of S100A14 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 2:176,008,395...176,010,423
Ensembl chr 2:178,306,025...178,307,999
|
|
| G
|
Saraf
|
store-operated calcium entry-associated regulatory factor
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of SARAF mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr16:64,720,404...64,738,653
Ensembl chr16:64,720,418...64,738,653
|
|
| G
|
Scamp4
|
secretory carrier membrane protein 4
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of SCAMP4 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 7:9,752,193...9,764,614
Ensembl chr 7:9,752,193...9,778,736
|
|
| G
|
Sdcbp
|
syndecan binding protein
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of SDCBP mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 5:19,473,499...19,517,188
Ensembl chr 5:24,245,033...24,326,197
|
|
| G
|
Selenop
|
selenoprotein P
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of SELENOP mRNA
|
CTD |
PMID:18497975 |
|
NCBI chr 2:54,225,736...54,236,022
Ensembl chr 2:54,225,152...54,236,019
|
|
| G
|
Sema3a
|
semaphorin 3A
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of SEMA3A mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 4:21,282,398...21,754,834
Ensembl chr 4:22,245,322...22,535,774
|
|
| G
|
Septin11
|
septin 11
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of SEPTIN11 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr14:15,119,760...15,275,222
Ensembl chr14:15,128,951...15,275,200
|
|
| G
|
Serpinc1
|
serpin family C member 1
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of SERPINC1
|
CTD |
PMID:1828463 |
|
NCBI chr13:75,790,558...75,804,826
Ensembl chr13:75,790,546...75,817,643
|
|
| G
|
Serpine1
|
serpin family E member 1
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of SERPINE1 mRNA; Medroxyprogesterone Acetate results in increased expression of SERPINE1 protein
|
CTD |
PMID:16011840 PMID:20843944 |
|
NCBI chr12:25,237,977...25,248,356
Ensembl chr12:25,237,952...25,248,357
|
|
| G
|
Sfn
|
stratifin
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Medroxyprogesterone Acetate co-treated with Bucladesine co-treated with decitabine] results in increased expression of SFN mRNA; [Estradiol co-treated with Medroxyprogesterone Acetate co-treated with Bucladesine] results in increased expression of SFN protein
|
CTD |
PMID:22534328 |
|
NCBI chr 5:151,110,582...151,111,854
Ensembl chr 5:151,110,530...151,111,995
|
|
| G
|
Sgk1
|
serum/glucocorticoid regulated kinase 1
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of SGK1 mRNA
|
CTD |
PMID:18497975 |
|
NCBI chr 1:24,799,391...24,916,886
Ensembl chr 1:24,799,396...24,807,231
|
|
| G
|
Sirt1
|
sirtuin 1
|
multiple interactions
|
ISO
|
[Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of SIRT1 protein
|
CTD |
PMID:16709600 |
|
NCBI chr20:25,305,953...25,328,000
Ensembl chr20:25,305,476...25,328,000
|
|
| G
|
Slc1a3
|
solute carrier family 1 member 3
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of SLC1A3 mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr 2:59,482,707...59,557,808
Ensembl chr 2:59,482,709...59,557,808
|
|
| G
|
Slc46a2
|
solute carrier family 46, member 2
|
decreases expression
|
ISO
|
Medroxyprogesterone Acetate results in decreased expression of SLC46A2 mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr 5:74,800,226...74,808,128
Ensembl chr 5:79,595,150...79,603,114
|
|
| G
|
Slc47a1
|
solute carrier family 47 member 1
|
decreases expression
|
ISO
|
Medroxyprogesterone Acetate results in decreased expression of SLC47A1 mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr10:46,034,115...46,088,617
Ensembl chr10:46,533,583...46,587,096
|
|
| G
|
Slc5a3
|
solute carrier family 5 member 3
|
decreases expression
|
ISO
|
Medroxyprogesterone Acetate results in decreased expression of SLC5A3 mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr11:44,799,787...44,802,233
Ensembl chr11:44,790,297...44,818,157
|
|
| G
|
Slc7a2
|
solute carrier family 7 member 2
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of SLC7A2 mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr16:58,115,991...58,174,256
Ensembl chr16:58,120,968...58,174,256
|
|
| G
|
Slc7a8
|
solute carrier family 7 member 8
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of SLC7A8 mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr15:32,153,016...32,212,715
Ensembl chr15:32,153,018...32,212,715
|
|
| G
|
Slc9a9
|
solute carrier family 9 member A9
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of SLC9A9 mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr 8:104,112,279...104,675,944
Ensembl chr 8:104,112,559...104,676,891
|
|
| G
|
Sln
|
sarcolipin
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of SLN mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr 8:54,221,389...54,248,110
Ensembl chr 8:63,139,722...63,143,971
|
|
| G
|
Smox
|
spermine oxidase
|
decreases expression
|
ISO
|
Medroxyprogesterone Acetate results in decreased expression of SMOX mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr 3:139,184,793...139,220,174
Ensembl chr 3:139,184,798...139,220,170 Ensembl chr X:139,184,798...139,220,170
|
|
| G
|
Sod1
|
superoxide dismutase 1
|
multiple interactions increases expression increases activity
|
ISO
|
[Estradiol co-treated with Medroxyprogesterone Acetate] results in increased activity of SOD1 protein; [Estradiol co-treated with Medroxyprogesterone Acetate] results in increased expression of SOD1 mRNA; [Estradiol deficiency co-treated with Medroxyprogesterone Acetate deficiency] results in decreased activity of SOD1 protein; [Estradiol deficiency co-treated with Medroxyprogesterone Acetate deficiency] results in decreased expression of SOD1 mRNA; [Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of SOD1 mRNA; Estradiol promotes the reaction [Medroxyprogesterone Acetate results in increased activity of SOD1 protein] Medroxyprogesterone Acetate results in increased expression of SOD1 mRNA
|
CTD |
PMID:11756571 PMID:12093828 PMID:16709600 |
|
NCBI chr11:42,942,742...42,948,399
Ensembl chr11:42,942,678...42,948,399
|
|
| G
|
Sod2
|
superoxide dismutase 2
|
multiple interactions affects expression increases expression increases activity
|
ISO EXP
|
[Estradiol co-treated with Medroxyprogesterone Acetate] results in increased activity of SOD2 protein; [Estradiol co-treated with Medroxyprogesterone Acetate] results in increased expression of SOD2 mRNA; [Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of SOD2 mRNA; [Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of SOD2 protein; FOXO1 protein affects the reaction [[Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of SOD2 mRNA]; Medroxyprogesterone Acetate promotes the reaction [CREBBP protein binds to SOD2 promoter]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Medroxyprogesterone Acetate results in increased expression of SOD2 mRNA]; protein kinase inhibitor peptide inhibits the reaction [[Estradiol co-treated with Medroxyprogesterone Acetate] results in increased activity of SOD2 protein]; WNT5A protein affects the reaction [[Medroxyprogesterone Acetate results in increased abundance of Cyclic AMP] which results in increased expression of SOD2 mRNA] [Medroxyprogesterone Acetate co-treated with Estradiol] affects the expression of SOD2 Medroxyprogesterone Acetate affects the expression of SOD2 Medroxyprogesterone Acetate results in increased activity of SOD2 protein
|
CTD |
PMID:11756571 PMID:12093828 PMID:16709600 PMID:20685861 PMID:21159850 |
|
NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:50,043,325...50,050,168
|
|
| G
|
Spp1
|
secreted phosphoprotein 1
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of SPP1 mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr14:5,613,569...5,620,695
Ensembl chr14:5,613,576...5,619,820
|
|
| G
|
Spry1
|
sprouty RTK signaling antagonist 1
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of SPRY1 mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr 2:122,484,995...122,490,008
Ensembl chr 2:122,484,355...122,492,956
|
|
| G
|
Srpx
|
sushi-repeat-containing protein, X-linked
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of SRPX mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr X:12,676,984...12,751,296
Ensembl chr X:15,349,440...15,420,392
|
|
| G
|
Srsf7
|
serine and arginine rich splicing factor 7
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of SRSF7 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 6:20,564,035...20,571,205
Ensembl chr 6:20,564,044...20,571,212
|
|
| G
|
Stk38
|
serine/threonine kinase 38
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of STK38 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr20:7,034,245...7,067,803
Ensembl chr20:7,035,933...7,069,711
|
|
| G
|
Stom
|
stomatin
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of STOM mRNA
|
CTD |
PMID:18497975 |
|
NCBI chr 3:39,042,503...39,064,818
Ensembl chr 3:39,042,503...39,064,818
|
|
| G
|
Sulf1
|
sulfatase 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of SULF1 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 5:11,145,950...11,308,622
Ensembl chr 5:11,145,950...11,308,643
|
|
| G
|
Tagln
|
transgelin
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of TAGLN mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 8:55,121,647...55,127,121
Ensembl chr 8:55,121,301...55,127,563
|
|
| G
|
Tbxas1
|
thromboxane A synthase 1
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of TBXAS1 mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr 4:68,631,841...68,803,959
Ensembl chr 4:68,631,838...68,803,969
|
|
| G
|
Tcea1
|
transcription elongation factor A1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of TCEA1 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 5:14,631,454...14,668,769
Ensembl chr15:12,831,339...12,834,156 Ensembl chr 5:12,831,339...12,834,156
|
|
| G
|
Tdo2
|
tryptophan 2,3-dioxygenase
|
multiple interactions
|
ISO
|
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[IFNG protein co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of TDO2 mRNA]; [IFNG protein co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of TDO2 mRNA
|
CTD |
PMID:32781018 |
|
NCBI chr 2:169,567,656...169,585,586
Ensembl chr 2:169,567,654...169,585,586
|
|
| G
|
Tert
|
telomerase reverse transcriptase
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of TERT mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 1:29,637,213...29,659,561
Ensembl chr 1:31,466,056...31,488,111
|
|
| G
|
Tfpi
|
tissue factor pathway inhibitor
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of TFPI mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr 3:69,533,156...69,582,547
Ensembl chr 3:89,939,868...89,980,742
|
|
| G
|
Tfpi2
|
tissue factor pathway inhibitor 2
|
decreases expression
|
ISO
|
Medroxyprogesterone Acetate results in decreased expression of TFPI2 mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr 4:32,936,462...32,941,385
Ensembl chr 4:32,936,854...32,941,426
|
|
| G
|
Tgfb3
|
transforming growth factor, beta 3
|
decreases expression
|
ISO
|
Medroxyprogesterone Acetate results in decreased expression of TGFB3 mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr 6:111,435,170...111,457,646
Ensembl chr 6:111,435,170...111,456,946
|
|
| G
|
Tgfbr2
|
transforming growth factor, beta receptor 2
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of TGFBR2 mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr 8:124,672,677...124,761,741
Ensembl chr 8:124,674,986...124,761,469
|
|
| G
|
Thbs1
|
thrombospondin 1
|
decreases expression
|
ISO
|
Medroxyprogesterone Acetate results in decreased expression of THBS1 mRNA
|
CTD |
PMID:18497975 |
|
NCBI chr 3:125,510,250...125,525,402
Ensembl chr 3:125,510,250...125,525,402
|
|
| G
|
Timp3
|
TIMP metallopeptidase inhibitor 3
|
decreases expression
|
ISO
|
Medroxyprogesterone Acetate results in decreased expression of TIMP3 mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr 7:19,408,539...19,459,558
Ensembl chr 7:19,409,631...19,459,547
|
|
| G
|
Tmem158
|
transmembrane protein 158
|
decreases expression
|
ISO
|
Medroxyprogesterone Acetate results in decreased expression of TMEM158 mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr 8:131,791,137...131,792,135
Ensembl chr 8:131,787,277...131,796,882
|
|
| G
|
Tnc
|
tenascin C
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of TNC mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 5:82,391,340...82,476,197
Ensembl chr 5:82,391,340...82,476,131
|
|
| G
|
Tnf
|
tumor necrosis factor
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Medroxyprogesterone Acetate] results in decreased secretion of TNF protein; [Polyphenols co-treated with Antioxidants co-treated with Eicosapentaenoic Acid co-treated with Docosahexaenoic Acids co-treated with Medroxyprogesterone Acetate co-treated with Celecoxib] results in decreased expression of TNF
|
CTD |
PMID:15866426 PMID:16702388 |
|
NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
|
|
| G
|
Tox2
|
TOX high mobility group box family member 2
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of TOX2 mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr 3:172,272,718...172,400,235
Ensembl chr 3:172,272,736...172,400,233
|
|
| G
|
Tp53
|
tumor protein p53
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Medroxyprogesterone Acetate co-treated with Bucladesine co-treated with decitabine] results in increased expression of TP53 protein; [Estradiol co-treated with Medroxyprogesterone Acetate co-treated with Bucladesine] results in increased expression of TP53 protein
|
CTD |
PMID:22534328 |
|
NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299
|
|
| G
|
Tpd52
|
tumor protein D52
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of TPD52 mRNA
|
CTD |
PMID:18497975 |
|
NCBI chr 2:94,642,514...94,723,442
Ensembl chr 2:94,642,585...94,724,241
|
|
| G
|
Tpi1
|
triosephosphate isomerase 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of TPI1 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 4:159,301,558...159,305,088
Ensembl chr 4:159,301,562...159,305,413
|
|
| G
|
Tpsg1
|
tryptase gamma 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of TPSG1 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr10:14,889,838...14,895,605
Ensembl chr10:14,890,734...14,894,786
|
|
| G
|
Tsc22d3
|
TSC22 domain family, member 3
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of TSC22D3 mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr X:109,006,410...109,066,389
Ensembl chr X:109,006,420...109,015,519
|
|
| G
|
Tsku
|
tsukushi, small leucine rich proteoglycan
|
decreases expression
|
ISO
|
Medroxyprogesterone Acetate results in decreased expression of TSKU mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr 1:162,071,459...162,082,972
Ensembl chr 1:162,064,126...162,089,272
|
|
| G
|
Txn1
|
thioredoxin 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of TXN mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 5:77,507,455...77,519,685
Ensembl chr 5:77,507,321...77,520,307
|
|
| G
|
Ube2d2b
|
ubiquitin-conjugating enzyme E2D 2B
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of UBE2D4 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr14:2,060,926...2,062,400
Ensembl chr14:2,048,235...2,063,764
|
|
| G
|
Ugcg
|
UDP-glucose ceramide glucosyltransferase
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of UGCG mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 5:78,828,006...78,860,725
Ensembl chr 5:78,828,006...78,860,417
|
|
| G
|
Usp12
|
ubiquitin specific peptidase 12
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of USP12 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr12:13,423,625...13,477,547
Ensembl chr12:13,422,427...13,477,547
|
|
| G
|
Vcam1
|
vascular cell adhesion molecule 1
|
multiple interactions
|
ISO
|
Medroxyprogesterone Acetate inhibits the reaction [Hydrocortisone inhibits the reaction [Lipopolysaccharides results in increased expression of VCAM1 protein]]; Medroxyprogesterone Acetate inhibits the reaction [Lipopolysaccharides results in increased expression of VCAM1 protein]; Mifepristone inhibits the reaction [Medroxyprogesterone Acetate inhibits the reaction [Lipopolysaccharides results in increased expression of VCAM1 protein]]
|
CTD |
PMID:15358673 |
|
NCBI chr 2:206,723,050...206,742,783
Ensembl chr 2:206,723,044...206,742,801
|
|
| G
|
Vdr
|
vitamin D receptor
|
multiple interactions
|
ISO
|
VDR gene polymorphism affects the susceptibility to [Alendronate co-treated with Estrogens, Conjugated (USP) co-treated with Medroxyprogesterone Acetate]; VDR gene polymorphism affects the susceptibility to [Estrogens, Conjugated (USP) co-treated with Medroxyprogesterone Acetate]
|
CTD |
PMID:15739035 |
|
NCBI chr 7:128,987,981...129,037,677
Ensembl chr 7:130,866,745...130,916,757
|
|
| G
|
Vegfa
|
vascular endothelial growth factor A
|
increases expression multiple interactions
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of VEGFA mRNA; Medroxyprogesterone Acetate results in increased expression of VEGFA mRNA alternative form Mifepristone inhibits the reaction [Medroxyprogesterone Acetate results in increased expression of VEGFA mRNA]
|
CTD |
PMID:15860260 PMID:17010073 |
|
NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194
|
|
| G
|
Vim
|
vimentin
|
multiple interactions
|
ISO
|
[Azacitidine co-treated with Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of VIM protein
|
CTD |
PMID:20823114 |
|
NCBI chr17:81,577,261...81,585,746
Ensembl chr17:81,568,272...81,585,746
|
|
| G
|
Vmo1
|
vitelline membrane outer layer 1 homolog
|
decreases expression
|
ISO
|
Medroxyprogesterone Acetate results in decreased expression of VMO1 mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr10:55,726,572...55,733,432
Ensembl chr10:55,726,572...55,727,856
|
|
| G
|
Vps39
|
VPS39 subunit of HOPS complex
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of VPS39 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 3:107,266,846...107,304,884
Ensembl chr 3:127,721,076...127,758,768
|
|
| G
|
Vsig4
|
V-set and immunoglobulin domain containing 4
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of VSIG4 mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr X:61,144,926...61,170,212
Ensembl chr X:65,154,424...65,179,708
|
|
| G
|
Wnt5a
|
Wnt family member 5A
|
multiple interactions increases expression
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of WNT5A mRNA; WNT5A protein affects the reaction [[Medroxyprogesterone Acetate results in increased abundance of Cyclic AMP] which results in increased expression of SOD2 mRNA]; WNT5A protein affects the reaction [Medroxyprogesterone Acetate results in increased abundance of Cyclic AMP] Medroxyprogesterone Acetate results in increased expression of WNT5A mRNA
|
CTD |
PMID:20685861 PMID:20823114 |
|
NCBI chr16:3,702,300...3,724,860
Ensembl chr16:3,703,665...3,724,860
|
|
| G
|
Wwtr1
|
WW domain containing transcription regulator 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of WWTR1 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 2:143,801,181...143,916,941
Ensembl chr 2:143,801,181...143,991,950
|
|
| G
|
Zbtb16
|
zinc finger and BTB domain containing 16
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of ZBTB16 mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr 8:57,885,886...58,073,507
Ensembl chr 8:57,891,081...58,073,507
|
|
| G
|
Zbtb45
|
zinc finger and BTB domain containing 45
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of ZBTB45 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 1:73,634,895...73,639,802
Ensembl chr 1:82,707,634...82,710,277
|
|
| G
|
Zfp36
|
zinc finger protein 36
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of ZFP36 mRNA
|
CTD |
PMID:15866426 |
|
NCBI chr 1:92,796,628...92,799,108
Ensembl chr 1:92,796,628...92,799,108
|
|
| G
|
Zfp36l1
|
zinc finger protein 36, C3H type-like 1
|
multiple interactions
|
ISO
|
[Medroxyprogesterone Acetate co-treated with Estradiol] results in increased expression of ZFP36L1 mRNA
|
CTD |
PMID:19146866 |
|
NCBI chr 6:98,930,705...98,935,748
Ensembl chr 6:104,663,399...104,687,979
|
|
| G
|
Zpld1
|
zona pellucida-like domain containing 1
|
increases expression
|
ISO
|
Medroxyprogesterone Acetate results in increased expression of ZPLD1 mRNA
|
CTD |
PMID:20843944 |
|
NCBI chr11:58,933,803...58,993,503
Ensembl chr11:58,951,901...58,991,704
|
|
| G
|
Zscan10
|
zinc finger and SCAN domain containing 10
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of ZSCAN10 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr10:12,636,302...12,646,275
Ensembl chr10:13,140,929...13,150,897
|
|
| G
|
Zscan20
|
zinc finger and SCAN domain containing 20
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of ZSCAN20 mRNA
|
CTD |
PMID:20823114 |
|
NCBI chr 5:140,926,596...140,956,285
Ensembl chr 5:146,215,082...146,240,777
|
|
|
|
| G
|
Clu
|
clusterin
|
affects expression
|
ISO
|
Megestrol affects the expression of CLU protein
|
CTD |
PMID:12388792 |
|
NCBI chr15:44,336,619...44,375,861
Ensembl chr15:44,359,914...44,375,860
|
|
| G
|
Gal
|
galanin and GMAP prepropeptide
|
affects expression
|
ISO
|
Megestrol affects the expression of GAL protein
|
CTD |
PMID:12388792 |
|
NCBI chr 1:200,650,439...200,655,302
Ensembl chr 1:210,079,702...210,084,229
|
|
| G
|
Gap43
|
growth associated protein 43
|
affects expression
|
ISO
|
Megestrol affects the expression of GAP43 protein
|
CTD |
PMID:12388792 |
|
NCBI chr11:71,882,131...71,975,799
Ensembl chr11:71,882,131...71,975,797
|
|
| G
|
Nr1i2
|
nuclear receptor subfamily 1, group I, member 2
|
increases activity
|
ISO
|
Megestrol results in increased activity of NR1I2 protein
|
CTD |
PMID:21068194 |
|
NCBI chr11:75,965,717...76,006,733
Ensembl chr11:75,965,632...76,002,380
|
|
| G
|
Ret
|
ret proto-oncogene
|
affects expression
|
ISO
|
Megestrol affects the expression of RET protein
|
CTD |
PMID:12388792 |
|
NCBI chr 4:151,325,969...151,368,176
Ensembl chr 4:152,998,812...153,040,556
|
|
| G
|
Timp1
|
TIMP metallopeptidase inhibitor 1
|
affects expression
|
ISO
|
Megestrol affects the expression of TIMP1 protein
|
CTD |
PMID:12388792 |
|
NCBI chr X:3,766,509...3,772,578
Ensembl chr X:3,766,510...3,771,135
|
|
|
|
| G
|
Abcb11
|
ATP binding cassette subfamily B member 11
|
decreases activity
|
ISO
|
Megestrol Acetate results in decreased activity of ABCB11 protein
|
CTD |
PMID:23956101 |
|
NCBI chr 3:74,424,620...74,520,646
Ensembl chr 3:74,424,979...74,520,581
|
|
| G
|
Ahsa1
|
activator of Hsp90 ATPase activity 1
|
increases expression
|
ISO
|
Megestrol Acetate results in increased expression of AHSA1 protein
|
CTD |
PMID:16939895 |
|
NCBI chr 6:106,913,296...106,921,347
Ensembl chr 6:112,644,479...112,655,595
|
|
| G
|
Ar
|
androgen receptor
|
multiple interactions
|
ISO
|
Megestrol Acetate binds to and results in decreased activity of AR protein
|
CTD |
PMID:25752796 |
|
NCBI chr X:67,135,317...67,304,476
Ensembl chr X:67,135,317...67,304,467
|
|
| G
|
Bcl11b
|
BCL11 transcription factor B
|
multiple interactions
|
EXP
|
[Ethinyl Estradiol co-treated with Megestrol Acetate] results in decreased expression of BCL11B mRNA
|
CTD |
PMID:22085904 |
|
NCBI chr 6:132,598,968...132,692,123
Ensembl chr 6:132,598,968...132,691,301
|
|
| G
|
Cct6a
|
chaperonin containing TCP1 subunit 6A
|
increases expression
|
ISO
|
Megestrol Acetate results in increased expression of CCT6A protein
|
CTD |
PMID:16939895 |
|
NCBI chr12:32,508,842...32,519,072
Ensembl chr12:32,508,675...32,519,119
|
|
| G
|
Cldn1
|
claudin 1
|
multiple interactions decreases expression
|
ISO
|
Megestrol Acetate results in decreased expression of and affects the localization of CLDN1 protein Megestrol Acetate results in decreased expression of CLDN1 mRNA
|
CTD |
PMID:22883527 |
|
NCBI chr11:87,926,376...87,941,533
Ensembl chr11:87,926,337...87,941,529
|
|
| G
|
Cldn4
|
claudin 4
|
multiple interactions decreases expression
|
ISO
|
Megestrol Acetate results in decreased expression of and results in increased localization of CLDN4 protein Megestrol Acetate results in decreased expression of CLDN4 mRNA
|
CTD |
PMID:23095775 |
|
NCBI chr12:27,388,160...27,389,958
Ensembl chr12:27,387,981...27,389,958
|
|
| G
|
Comt
|
catechol-O-methyltransferase
|
increases expression
|
ISO
|
Megestrol Acetate results in increased expression of COMT protein
|
CTD |
PMID:16939895 |
|
NCBI chr11:96,072,371...96,091,956
Ensembl chr11:96,072,489...96,092,533
|
|
| G
|
Esr1
|
estrogen receptor 1
|
multiple interactions
|
ISO
|
ESR1 protein affects the reaction [Megestrol Acetate results in increased expression of GREB1 mRNA]
|
CTD |
PMID:33405908 |
|
NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:43,644,392...43,900,354
|
|
| G
|
Greb1
|
growth regulating estrogen receptor binding 1
|
increases expression multiple interactions
|
ISO
|
Megestrol Acetate results in increased expression of GREB1 mRNA ESR1 protein affects the reaction [Megestrol Acetate results in increased expression of GREB1 mRNA]; Fulvestrant inhibits the reaction [Megestrol Acetate results in increased expression of GREB1 mRNA]
|
CTD |
PMID:33405908 |
|
NCBI chr 6:45,169,289...45,321,973
Ensembl chr 6:45,169,289...45,291,126
|
|
| G
|
Krt8
|
keratin 8
|
increases expression
|
ISO
|
Megestrol Acetate results in increased expression of KRT8 protein
|
CTD |
PMID:16939895 |
|
NCBI chr 7:135,002,886...135,010,339
Ensembl chr 7:135,002,894...135,010,403
|
|
| G
|
Mmp12
|
matrix metallopeptidase 12
|
multiple interactions
|
EXP
|
[Ethinyl Estradiol co-treated with Megestrol Acetate] results in increased expression of MMP12 protein
|
CTD |
PMID:22085904 |
|
NCBI chr 8:4,581,785...4,591,687
Ensembl chr 8:12,866,641...12,884,478
|
|
| G
|
Mmp3
|
matrix metallopeptidase 3
|
multiple interactions
|
EXP
|
[Ethinyl Estradiol co-treated with Megestrol Acetate] results in increased expression of MMP3 protein
|
CTD |
PMID:22085904 |
|
NCBI chr 8:12,925,267...12,938,828
Ensembl chr 8:12,925,280...12,938,826
|
|
| G
|
Mmp8
|
matrix metallopeptidase 8
|
multiple interactions
|
EXP
|
[Ethinyl Estradiol co-treated with Megestrol Acetate] results in increased expression of MMP8 protein
|
CTD |
PMID:22085904 |
|
NCBI chr 8:4,724,009...4,733,864
Ensembl chr 8:13,008,890...13,018,729
|
|
| G
|
Pgr
|
progesterone receptor
|
multiple interactions
|
ISO
|
Megestrol Acetate binds to and results in increased activity of PGR protein
|
CTD |
PMID:25752796 |
|
NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:14,354,398...14,413,271
|
|
| G
|
Ppia
|
peptidylprolyl isomerase A
|
decreases expression
|
ISO
|
Megestrol Acetate results in decreased expression of PPIA protein
|
CTD |
PMID:16939895 |
|
NCBI chr14:81,279,292...81,282,960
Ensembl chr14:85,492,484...85,497,115
|
|
| G
|
Rab6a
|
RAB6A, member RAS oncogene family
|
increases expression
|
ISO
|
Megestrol Acetate results in increased expression of RAB6A protein
|
CTD |
PMID:16939895 |
|
NCBI chr 1:154,957,870...155,008,922
Ensembl chr 1:164,369,861...164,417,763
|
|
| G
|
Sf3a3
|
splicing factor 3a, subunit 3
|
increases expression
|
ISO
|
Megestrol Acetate results in increased expression of SF3A3 protein
|
CTD |
PMID:16939895 |
|
NCBI chr 5:136,967,713...136,987,345
Ensembl chr 5:142,246,568...142,272,052
|
|
| G
|
Sgk1
|
serum/glucocorticoid regulated kinase 1
|
increases expression multiple interactions
|
ISO
|
Megestrol Acetate results in increased expression of SGK1 mRNA Fulvestrant inhibits the reaction [Megestrol Acetate results in increased expression of SGK1 mRNA]
|
CTD |
PMID:33405908 |
|
NCBI chr 1:24,799,391...24,916,886
Ensembl chr 1:24,799,396...24,807,231
|
|
| G
|
Slc22a2
|
solute carrier family 22 member 2
|
multiple interactions
|
ISO
|
Megestrol Acetate inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium]
|
CTD |
PMID:21599003 |
|
NCBI chr 1:50,668,817...50,711,019
Ensembl chr 1:50,668,817...50,711,019
|
|
| G
|
Tnc
|
tenascin C
|
multiple interactions
|
EXP
|
[Ethinyl Estradiol co-treated with Megestrol Acetate] results in decreased expression of TNC mRNA
|
CTD |
PMID:22085904 |
|
NCBI chr 5:82,391,340...82,476,197
Ensembl chr 5:82,391,340...82,476,131
|
|
|
|
| G
|
Abcb1a
|
ATP binding cassette subfamily B member 1A
|
multiple interactions
|
ISO
|
Mometasone Furoate inhibits the reaction [ABCB1 protein results in decreased susceptibility to Doxorubicin]; Mometasone Furoate inhibits the reaction [ABCB1 protein results in increased export of fluorexon]
|
CTD |
PMID:16442095 |
|
NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:26,312,409...26,397,135
|
|
| G
|
Abcg2
|
ATP binding cassette subfamily G member 2
|
multiple interactions increases activity
|
ISO
|
Mometasone Furoate inhibits the reaction [ABCG2 protein results in increased export of Mitoxantrone] Mometasone Furoate results in increased activity of ABCG2 protein
|
CTD |
PMID:16442095 |
|
NCBI chr 4:89,006,056...89,132,915
Ensembl chr 4:89,005,969...89,132,493
|
|
| G
|
Csf2
|
colony stimulating factor 2
|
multiple interactions
|
ISO
|
Mometasone Furoate inhibits the reaction [IL1B protein results in increased secretion of CSF2 protein]
|
CTD |
PMID:10460758 |
|
NCBI chr10:38,887,692...38,889,673
Ensembl chr10:38,887,692...38,890,031
|
|
| G
|
Cyp2c79
|
cytochrome P450, family 2, subfamily c, polypeptide 79
|
decreases activity
|
ISO
|
Mometasone Furoate results in decreased activity of CYP2C8 protein
|
CTD |
PMID:15601807 |
|
|
|
| G
|
F3
|
coagulation factor III, tissue factor
|
increases expression
|
ISO
|
Mometasone Furoate results in increased expression of F3 protein
|
CTD |
PMID:25569083 |
|
NCBI chr 2:212,511,675...212,523,375
Ensembl chr 2:212,511,680...212,523,369
|
|
| G
|
Hsf1
|
heat shock transcription factor 1
|
increases activity
|
ISO
|
Mometasone Furoate results in increased activity of HSF1 protein
|
CTD |
PMID:34170685 |
|
NCBI chr 7:110,076,710...110,103,665
Ensembl chr 7:110,076,710...110,103,665
|
|
| G
|
Il10
|
interleukin 10
|
decreases secretion
|
ISO
|
Mometasone Furoate results in decreased secretion of IL10 protein
|
CTD |
PMID:9819297 |
|
NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580
|
|
| G
|
Il12b
|
interleukin 12B
|
multiple interactions
|
ISO
|
Mometasone Furoate inhibits the reaction [endotoxin, Escherichia coli results in increased secretion of IL12B protein]
|
CTD |
PMID:19422381 |
|
NCBI chr10:29,390,300...29,405,194
Ensembl chr10:29,389,905...29,405,194
|
|
| G
|
Il1b
|
interleukin 1 beta
|
multiple interactions
|
ISO
|
Mometasone Furoate inhibits the reaction [IL1B protein results in increased secretion of CSF2 protein]
|
CTD |
PMID:10460758 |
|
NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
|
|
| G
|
Nr3c1
|
nuclear receptor subfamily 3, group C, member 1
|
affects binding
|
EXP ISO
|
Mometasone Furoate binds to NR3C1 protein
|
CTD |
PMID:16507850 PMID:19422381 |
|
NCBI chr18:31,522,783...31,644,508
Ensembl chr18:31,522,783...31,643,843
|
|
| G
|
Nr3c2
|
nuclear receptor subfamily 3, group C, member 2
|
affects binding
|
ISO
|
Mometasone Furoate binds to NR3C2 protein
|
CTD |
PMID:19422381 |
|
NCBI chr19:47,619,853...47,964,089
Ensembl chr19:47,619,853...47,964,078
|
|
| G
|
Pgr
|
progesterone receptor
|
multiple interactions affects binding
|
ISO
|
Mometasone Furoate binds to and results in increased activity of PGR protein Mometasone Furoate binds to PGR protein
|
CTD |
PMID:15189034 PMID:19422381 |
|
NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:14,354,398...14,413,271
|
|
| G
|
Spp1
|
secreted phosphoprotein 1
|
increases expression
|
ISO
|
Mometasone Furoate results in increased expression of SPP1 protein
|
CTD |
PMID:21885873 |
|
NCBI chr14:5,613,569...5,620,695
Ensembl chr14:5,613,576...5,619,820
|
|
| G
|
Tat
|
tyrosine aminotransferase
|
increases activity
|
ISO
|
Mometasone Furoate results in increased activity of TAT protein
|
CTD |
PMID:19422381 |
|
NCBI chr19:54,856,604...54,867,168
Ensembl chr19:54,856,563...54,867,482
|
|
| G
|
Tgm2
|
transglutaminase 2
|
increases expression
|
ISO
|
Mometasone Furoate results in increased expression of TGM2 protein
|
CTD |
PMID:21885873 |
|
NCBI chr 3:167,192,612...167,221,845
Ensembl chr 3:167,192,612...167,304,240
|
|
| G
|
Tnf
|
tumor necrosis factor
|
multiple interactions decreases secretion
|
ISO
|
Mometasone Furoate inhibits the reaction [TNF protein results in increased expression of VCAM1 protein] Mometasone Furoate results in decreased secretion of TNF protein
|
CTD |
PMID:9819297 PMID:10100995 |
|
NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
|
|
| G
|
Vcam1
|
vascular cell adhesion molecule 1
|
multiple interactions
|
ISO
|
Mometasone Furoate inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]
|
CTD |
PMID:10100995 |
|
NCBI chr 2:206,723,050...206,742,783
Ensembl chr 2:206,723,044...206,742,801
|
|
|
|
| G
|
Abcb11
|
ATP binding cassette subfamily B member 11
|
decreases activity
|
ISO
|
Norethindrone results in decreased activity of ABCB11 protein
|
CTD |
PMID:20829430 |
|
NCBI chr 3:74,424,620...74,520,646
Ensembl chr 3:74,424,979...74,520,581
|
|
| G
|
Abcb1a
|
ATP binding cassette subfamily B member 1A
|
increases expression
|
ISO
|
Norethindrone results in increased expression of ABCB1 mRNA
|
CTD |
PMID:15290871 |
|
NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:26,312,409...26,397,135
|
|
| G
|
Adipoq
|
adiponectin, C1Q and collagen domain containing
|
multiple interactions
|
ISO
|
Norethindrone inhibits the reaction [[Dexamethasone co-treated with Rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of and results in increased secretion of ADIPOQ protein]
|
CTD |
PMID:29782964 |
|
NCBI chr11:91,226,524...91,240,244
Ensembl chr11:91,226,180...91,240,169
|
|
| G
|
Akr1c1
|
aldo-keto reductase family 1, member C1
|
decreases activity
|
ISO
|
Norethindrone results in decreased activity of AKR1C1 protein
|
CTD |
PMID:21182831 |
|
NCBI chr17:70,720,397...70,747,285
Ensembl chr17:70,720,398...70,747,247
|
|
| G
|
Akr1c3
|
aldo-keto reductase family 1, member C3
|
decreases activity
|
ISO
|
Norethindrone results in decreased activity of AKR1C3 protein
|
CTD |
PMID:21182831 |
|
NCBI chr17:71,020,884...71,037,779
Ensembl chr17:70,970,900...71,048,438
|
|
| G
|
Ar
|
androgen receptor
|
affects binding multiple interactions
|
EXP ISO
|
Norethindrone binds to AR protein Norethindrone binds to and results in decreased activity of AR protein; Norethindrone binds to and results in increased activity of AR protein
|
CTD |
PMID:14565775 PMID:25752796 PMID:33049310 |
|
NCBI chr X:67,135,317...67,304,476
Ensembl chr X:67,135,317...67,304,467
|
|
| G
|
Bglap
|
bone gamma-carboxyglutamate protein
|
increases secretion
|
ISO
|
Norethindrone results in increased secretion of BGLAP protein
|
CTD |
PMID:8053399 |
|
NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:176,136,341...176,137,318
|
|
| G
|
Esr1
|
estrogen receptor 1
|
increases activity multiple interactions
|
EXP ISO
|
Norethindrone results in increased activity of ESR1 protein ESR1 protein affects the reaction [Norethindrone results in increased expression of GREB1 mRNA]; ESR1 protein affects the reaction [Norethindrone results in increased expression of SGK1 mRNA]; Norethindrone binds to and results in increased activity of ESR1 protein
|
CTD |
PMID:11750080 PMID:12504345 PMID:25012808 PMID:25752796 PMID:33049310 PMID:33405908 More...
|
|
NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:43,644,392...43,900,354
|
|
| G
|
Esr2
|
estrogen receptor 2
|
multiple interactions
|
ISO
|
Norethindrone binds to and results in increased activity of ESR2 protein
|
CTD |
PMID:25752796 PMID:33049310 |
|
NCBI chr 6:100,589,553...100,645,240
Ensembl chr 6:100,545,206...100,644,709
|
|
| G
|
F10
|
coagulation factor X
|
multiple interactions
|
ISO
|
[Ethinyl Estradiol binds to Norethindrone] which results in increased expression of F10 protein
|
CTD |
PMID:14561536 |
|
NCBI chr16:83,170,973...83,190,280
Ensembl chr16:83,170,977...83,190,280
|
|
| G
|
F7
|
coagulation factor VII
|
multiple interactions
|
ISO
|
[Ethinyl Estradiol binds to Norethindrone] which results in increased expression of F7 protein
|
CTD |
PMID:14561536 |
|
NCBI chr16:83,191,896...83,202,775
Ensembl chr16:83,191,914...83,202,738
|
|
| G
|
Fabp4
|
fatty acid binding protein 4
|
multiple interactions
|
ISO
|
Norethindrone inhibits the reaction [[Dexamethasone co-treated with Rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of FABP4 protein]
|
CTD |
PMID:29782964 |
|
NCBI chr 2:93,488,251...93,492,961
Ensembl chr 2:93,488,271...93,492,972
|
|
| G
|
Fasn
|
fatty acid synthase
|
increases activity
|
ISO
|
Norethindrone results in increased activity of FASN protein
|
CTD |
PMID:15870863 |
|
NCBI chr10:106,570,415...106,588,581
Ensembl chr10:106,570,413...106,588,583
|
|
| G
|
Fga
|
fibrinogen alpha chain
|
multiple interactions
|
ISO
|
[Ethinyl Estradiol co-treated with Norethindrone] results in increased expression of [FGA protein binds to FGB protein binds to FGG protein]
|
CTD |
PMID:14561536 |
|
NCBI chr 2:168,374,120...168,381,523
Ensembl chr 2:170,672,012...170,679,577
|
|
| G
|
Fgb
|
fibrinogen beta chain
|
multiple interactions
|
ISO
|
[Ethinyl Estradiol co-treated with Norethindrone] results in increased expression of [FGA protein binds to FGB protein binds to FGG protein]
|
CTD |
PMID:14561536 |
|
NCBI chr 2:170,693,966...170,700,875
Ensembl chr 2:170,692,965...170,705,434
|
|
| G
|
Fgg
|
fibrinogen gamma chain
|
multiple interactions
|
ISO
|
[Ethinyl Estradiol co-treated with Norethindrone] results in increased expression of [FGA protein binds to FGB protein binds to FGG protein]
|
CTD |
PMID:14561536 |
|
NCBI chr 2:170,652,929...170,660,372
Ensembl chr 2:170,652,234...170,661,170
|
|
| G
|
Greb1
|
growth regulating estrogen receptor binding 1
|
multiple interactions increases expression
|
ISO
|
ESR1 protein affects the reaction [Norethindrone results in increased expression of GREB1 mRNA]; Fulvestrant inhibits the reaction [Norethindrone results in increased expression of GREB1 mRNA]
|
CTD |
PMID:33405908 |
|
NCBI chr 6:45,169,289...45,321,973
Ensembl chr 6:45,169,289...45,291,126
|
|
| G
|
H2ax
|
H2A.X variant histone
|
increases phosphorylation
|
ISO
|
Norethindrone results in increased phosphorylation of H2AX protein
|
CTD |
PMID:15905198 |
|
NCBI chr 8:53,568,718...53,570,072
Ensembl chr 8:53,568,281...53,573,079
|
|
| G
|
Ins2
|
insulin 2
|
multiple interactions
|
ISO
|
Norethindrone inhibits the reaction [[Dexamethasone co-treated with Rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of and results in increased secretion of ADIPOQ protein]; Norethindrone inhibits the reaction [[Dexamethasone co-treated with Rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of FABP4 protein]
|
CTD |
PMID:29782964 |
|
NCBI chr 1:207,272,738...207,421,998
Ensembl chr 1:207,272,742...207,273,805
|
|
| G
|
Mapt
|
microtubule-associated protein tau
|
decreases expression
|
ISO
|
Norethindrone results in decreased expression of MAPT protein
|
CTD |
PMID:16930453 |
|
NCBI chr10:89,638,618...89,736,108
Ensembl chr10:89,638,599...89,736,108
|
|
| G
|
Mybl1
|
MYB proto-oncogene like 1
|
multiple interactions increases expression
|
ISO
|
Fulvestrant inhibits the reaction [Norethindrone results in increased expression of MYBL1 mRNA]
|
CTD |
PMID:33405908 |
|
NCBI chr 5:14,365,768...14,401,012
Ensembl chr 5:14,365,768...14,399,588
|
|
| G
|
Nr1i2
|
nuclear receptor subfamily 1, group I, member 2
|
multiple interactions
|
ISO
|
Norethindrone binds to and results in increased activity of NR1I2 protein
|
CTD |
PMID:33049310 |
|
NCBI chr11:75,965,717...76,006,733
Ensembl chr11:75,965,632...76,002,380
|
|
| G
|
Pgr
|
progesterone receptor
|
multiple interactions
|
ISO
|
Norethindrone binds to and results in increased activity of PGR protein
|
CTD |
PMID:15189034 PMID:25752796 |
|
NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:14,354,398...14,413,271
|
|
| G
|
Plg
|
plasminogen
|
multiple interactions
|
ISO
|
[Ethinyl Estradiol binds to Norethindrone] which results in increased expression of PLG protein
|
CTD |
PMID:14561536 |
|
NCBI chr 1:50,872,927...50,915,406
Ensembl chr 1:50,872,926...50,917,320
|
|
| G
|
Pparg
|
peroxisome proliferator-activated receptor gamma
|
multiple interactions
|
ISO
|
Norethindrone binds to and results in increased activity of PPARG protein
|
CTD |
PMID:33049310 |
|
NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104
|
|
| G
|
Proc
|
protein C, inactivator of coagulation factors Va and VIIIa
|
multiple interactions
|
ISO
|
[Ethinyl Estradiol binds to Norethindrone] which results in increased expression of PROC protein
|
CTD |
PMID:14561536 |
|
NCBI chr18:24,038,596...24,049,061
Ensembl chr18:24,038,597...24,048,964
|
|
| G
|
Serpinc1
|
serpin family C member 1
|
multiple interactions
|
ISO
|
[Ethinyl Estradiol binds to Norethindrone] which results in decreased expression of SERPINC1 protein
|
CTD |
PMID:14561536 |
|
NCBI chr13:75,790,558...75,804,826
Ensembl chr13:75,790,546...75,817,643
|
|
| G
|
Serpine1
|
serpin family E member 1
|
multiple interactions
|
ISO
|
[Ethinyl Estradiol binds to Norethindrone] which results in decreased expression of SERPINE1 protein
|
CTD |
PMID:14561536 |
|
NCBI chr12:25,237,977...25,248,356
Ensembl chr12:25,237,952...25,248,357
|
|
| G
|
Sgk1
|
serum/glucocorticoid regulated kinase 1
|
increases expression multiple interactions
|
ISO
|
Norethindrone results in increased expression of SGK1 mRNA ESR1 protein affects the reaction [Norethindrone results in increased expression of SGK1 mRNA]; Fulvestrant inhibits the reaction [Norethindrone results in increased expression of SGK1 mRNA]
|
CTD |
PMID:33405908 |
|
NCBI chr 1:24,799,391...24,916,886
Ensembl chr 1:24,799,396...24,807,231
|
|
| G
|
Slc22a2
|
solute carrier family 22 member 2
|
multiple interactions
|
ISO
|
Norethindrone inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium]
|
CTD |
PMID:21599003 |
|
NCBI chr 1:50,668,817...50,711,019
Ensembl chr 1:50,668,817...50,711,019
|
|
| G
|
Thra
|
thyroid hormone receptor alpha
|
multiple interactions
|
ISO
|
Norethindrone binds to and results in decreased activity of THRA protein
|
CTD |
PMID:33049310 |
|
NCBI chr10:84,198,141...84,225,659
Ensembl chr10:84,197,011...84,225,657
|
|
| G
|
Thrb
|
thyroid hormone receptor beta
|
multiple interactions
|
ISO
|
Norethindrone binds to and results in increased activity of THRB protein
|
CTD |
PMID:33049310 |
|
NCBI chr15:7,685,180...8,031,920
Ensembl chr15:10,115,954...10,313,680
|
|
| G
|
Tp53
|
tumor protein p53
|
multiple interactions
|
ISO
|
Norethindrone results in increased expression of and results in increased activity of TP53 protein
|
CTD |
PMID:15905198 |
|
NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299
|
|
| G
|
Vegfa
|
vascular endothelial growth factor A
|
increases expression
|
ISO
|
Norethindrone results in increased expression of VEGFA mRNA; Norethindrone results in increased expression of VEGFA mRNA alternative form
|
CTD |
PMID:17010073 |
|
NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194
|
|
|
|
| G
|
Abcc2
|
ATP binding cassette subfamily C member 2
|
decreases activity
|
ISO
|
norgestimate results in decreased activity of ABCC2 protein
|
CTD |
PMID:16049127 |
|
NCBI chr 1:252,613,875...252,672,459
Ensembl chr 1:252,614,017...252,673,471
|
|
| G
|
Ar
|
androgen receptor
|
multiple interactions affects localization decreases expression
|
ISO
|
norgestimate binds to and results in decreased activity of AR protein; norgestimate binds to and results in increased activity of AR protein norgestimate affects the localization of AR protein norgestimate results in decreased expression of AR mRNA
|
CTD |
PMID:17505938 PMID:28478275 |
|
NCBI chr X:67,135,317...67,304,476
Ensembl chr X:67,135,317...67,304,467
|
|
| G
|
Crp
|
C-reactive protein
|
multiple interactions
|
ISO
|
[Ethinyl Estradiol co-treated with norgestimate] results in increased expression of CRP protein
|
CTD |
PMID:16982228 |
|
NCBI chr13:87,694,062...87,695,978
Ensembl chr13:87,657,317...87,707,514
|
|
| G
|
Cyp1a2
|
cytochrome P450, family 1, subfamily a, polypeptide 2
|
multiple interactions
|
ISO
|
[Ethinyl Estradiol co-treated with norgestimate] results in decreased activity of CYP1A2 protein
|
CTD |
PMID:16291717 |
|
NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:66,971,261...66,978,149
|
|
| G
|
Cyp2c6
|
cytochrome P450, family 2, subfamily C, polypeptide 6
|
multiple interactions
|
ISO
|
[Ethinyl Estradiol co-treated with norgestimate] results in decreased activity of CYP2C19 protein
|
CTD |
PMID:16291717 |
|
NCBI chr 1:247,879,058...247,916,804
Ensembl chr 1:247,879,078...247,916,798
|
|
| G
|
F7
|
coagulation factor VII
|
multiple interactions
|
ISO
|
[Ethinyl Estradiol co-treated with norgestimate] results in increased expression of F7 protein
|
CTD |
PMID:12618251 |
|
NCBI chr16:83,191,896...83,202,775
Ensembl chr16:83,191,914...83,202,738
|
|
| G
|
F8
|
coagulation factor VIII
|
multiple interactions
|
ISO
|
[Ethinyl Estradiol co-treated with norgestimate] results in increased expression of F8 protein
|
CTD |
PMID:12618251 |
|
NCBI chr18:140,848...172,330
Ensembl chr18:155,309...186,683
|
|
| G
|
Fga
|
fibrinogen alpha chain
|
multiple interactions
|
ISO
|
[Ethinyl Estradiol co-treated with norgestimate] results in increased expression of [FGA protein binds to FGB protein binds to FGG protein]
|
CTD |
PMID:12618251 |
|
NCBI chr 2:168,374,120...168,381,523
Ensembl chr 2:170,672,012...170,679,577
|
|
| G
|
Fgb
|
fibrinogen beta chain
|
multiple interactions
|
ISO
|
[Ethinyl Estradiol co-treated with norgestimate] results in increased expression of [FGA protein binds to FGB protein binds to FGG protein]
|
CTD |
PMID:12618251 |
|
NCBI chr 2:170,693,966...170,700,875
Ensembl chr 2:170,692,965...170,705,434
|
|
| G
|
Fgg
|
fibrinogen gamma chain
|
multiple interactions
|
ISO
|
[Ethinyl Estradiol co-treated with norgestimate] results in increased expression of [FGA protein binds to FGB protein binds to FGG protein]
|
CTD |
PMID:12618251 |
|
NCBI chr 2:170,652,929...170,660,372
Ensembl chr 2:170,652,234...170,661,170
|
|
| G
|
Pgr
|
progesterone receptor
|
multiple interactions
|
ISO
|
norgestimate binds to and affects the activity of PGR protein
|
CTD |
PMID:1324557 PMID:15697108 |
|
NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:14,354,398...14,413,271
|
|
| G
|
Plat
|
plasminogen activator, tissue type
|
multiple interactions
|
ISO
|
[Ethinyl Estradiol co-treated with norgestimate] results in decreased expression of PLAT protein; [Ethinyl Estradiol co-treated with norgestimate] results in increased activity of PLAT protein
|
CTD |
PMID:12618251 |
|
NCBI chr16:75,943,061...76,022,037
Ensembl chr16:75,943,064...75,967,696
|
|
| G
|
Plg
|
plasminogen
|
multiple interactions
|
ISO
|
[Ethinyl Estradiol co-treated with norgestimate] results in increased expression of PLG protein
|
CTD |
PMID:12618251 |
|
NCBI chr 1:50,872,927...50,915,406
Ensembl chr 1:50,872,926...50,917,320
|
|
| G
|
Proc
|
protein C, inactivator of coagulation factors Va and VIIIa
|
multiple interactions
|
ISO
|
[Ethinyl Estradiol co-treated with norgestimate] results in increased expression of PROC protein
|
CTD |
PMID:12618251 |
|
NCBI chr18:24,038,596...24,049,061
Ensembl chr18:24,038,597...24,048,964
|
|
| G
|
Pros1
|
protein S
|
multiple interactions
|
ISO
|
[Ethinyl Estradiol co-treated with norgestimate] results in decreased expression of PROS1 protein
|
CTD |
PMID:12618251 |
|
NCBI chr11:230,597...311,288
Ensembl chr11:13,676,769...13,757,852
|
|
| G
|
Serpina6
|
serpin family A member 6
|
multiple interactions
|
ISO
|
[Ethinyl Estradiol co-treated with norgestimate] results in increased expression of SERPINA6 protein
|
CTD |
PMID:16982228 |
|
NCBI chr 6:122,780,040...122,790,274
Ensembl chr 6:128,544,831...128,555,139
|
|
| G
|
Serpina7
|
serpin family A member 7
|
multiple interactions
|
ISO
|
[Ethinyl Estradiol co-treated with norgestimate] results in increased expression of SERPINA7 protein
|
CTD |
PMID:16982228 |
|
NCBI chr X:107,452,044...107,510,958
Ensembl chr X:107,452,044...107,457,681
|
|
| G
|
Serpinc1
|
serpin family C member 1
|
multiple interactions
|
ISO
|
[Ethinyl Estradiol co-treated with norgestimate] results in decreased expression of SERPINC1 protein
|
CTD |
PMID:12618251 |
|
NCBI chr13:75,790,558...75,804,826
Ensembl chr13:75,790,546...75,817,643
|
|
| G
|
Shbg
|
sex hormone binding globulin
|
multiple interactions
|
ISO
|
[Ethinyl Estradiol co-treated with norgestimate] results in increased expression of SHBG protein
|
CTD |
PMID:12586319 PMID:16982228 |
|
NCBI chr10:54,831,716...54,849,162
Ensembl chr10:54,831,718...54,838,760
|
|
|
|
| G
|
Adipoq
|
adiponectin, C1Q and collagen domain containing
|
multiple interactions
|
ISO
|
Norgestrel inhibits the reaction [[Dexamethasone co-treated with Rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of and results in increased secretion of ADIPOQ protein]
|
CTD |
PMID:29782964 |
|
NCBI chr11:91,226,524...91,240,244
Ensembl chr11:91,226,180...91,240,169
|
|
| G
|
Ar
|
androgen receptor
|
multiple interactions
|
ISO
|
1-hydroxypyrene inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; 17 alpha-Hydroxyprogesterone Caproate inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; 17-alpha-Hydroxyprogesterone inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; 2,2',4,4'-tetrahydroxybenzophenone inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; 2,2'-bisphenol F inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; 2,2'-dihydroxy-6,6'-dinaphthyldisulfide inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; 2,4,6-triiodophenol inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; 2,5-di-tert-butylhydroquinone inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; 2-chloro-4-phenylphenol inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; 2-tert-butylhydroquinone inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; 2-tolidine inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; 3-iodo-2-propynylbutylcarbamate inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; 3-phenoxybenzylalcohol inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; 4,4'-dichlorodiphenyl sulfone inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; 4-cumylphenol inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; 4-phenylphenol inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; 4-tert-octylphenol inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; 7-dimethylamino-4-methylcoumarin inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; 9,10-Dimethyl-1,2-benzanthracene inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; 9-phenanthrol inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; [6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein; acetochlor inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; acetyl methyl tetramethyl tetralin inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; afimoxifene inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; alpha-isomethylionone inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; Apigenin inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; atraric acid inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; Azinphosmethyl inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; bicalutamide inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; bisphenol A inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; bisphenol AF inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; bromadiolone inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; bromuconazole inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; butylbenzyl phthalate inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; butylphen inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; Chlordecone inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; chlorobenzilate inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; chloroxylenol inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; Clomiphene inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; clorophene inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; Coumaphos inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; Cyproterone Acetate inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; d,d-T80-prallethrin inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; DDT inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; Dehydroepiandrosterone inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; devrinol inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; di-n-pentyl phthalate inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; diallyl phthalate inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; Dibutyl Phthalate inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; Dichlorodiphenyl Dichloroethylene inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; Dichlorodiphenyldichloroethane inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; dicloran inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; dimethomorph inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; diniconazole inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; Disulfiram inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; dithiopyr inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; Diuron inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; Endosulfan inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; enilconazole inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; Equilin inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; Estrone inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; ethafluralin inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; Ethinyl Estradiol inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; fenamiphos inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; fenarimol inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; Fenitrothion inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; Fenthion inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; Finasteride inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; fludioxonil inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; flumetralin inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; fluoranthene inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; Flutamide inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; Genistein inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; Hexestrol inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; hydroxyflutamide inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; iprodione inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; Linuron inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; Melengestrol Acetate inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; Mestranol inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; metconazole inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; Methoxychlor inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; Methyl Parathion inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; metolachlor inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; Mitotane inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; N-(2-ethylhexyl)-5-norbornene-2,3-dicarboxamide inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; nilutamide inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; nitrofen inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; nonylphenol inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; Norgestrel binds to and results in increased activity of AR protein; o,p'-DDT inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; oryzalin inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; oxybenzone inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; p-tert-amylphenol inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; pendimethalin inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; phenanthrene inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; phenothiazine inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; phosalone inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; phoxim inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; prochloraz inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; procymidone inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; pronamide inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; Propanil inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; propiconazole inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; propylparaben inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; pyrene inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; S-methyl benzo(1,2,3)thiadiazole-7-carbothioate inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; Spironolactone inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; tebuconazole inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; Testosterone Propionate inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; tetrabromobisphenol A inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; tetrachlorodian inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; Tetrachlorvinphos inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; tri-(2-ethylhexyl)trimellitate inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; tributyltin inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; Triclosan inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; triflumizol inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; Trifluralin inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; Triiodothyronine inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; triphenyl phosphate inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; triphenyltin chloride inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; tris(1,3-dichloro-2-propyl)phosphate inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; triticonazole inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; Troglitazone inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; vinclozolin inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]
|
CTD |
PMID:33049310 |
|
NCBI chr X:67,135,317...67,304,476
Ensembl chr X:67,135,317...67,304,467
|
|
| G
|
Esr1
|
estrogen receptor 1
|
increases activity multiple interactions
|
EXP ISO
|
Norgestrel results in increased activity of ESR1 protein Norgestrel binds to and results in increased activity of ESR1 protein
|
CTD |
PMID:11750080 PMID:12504345 PMID:33049310 |
|
NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:43,644,392...43,900,354
|
|
| G
|
Fabp4
|
fatty acid binding protein 4
|
multiple interactions
|
ISO
|
[Norgestrel co-treated with Rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of FABP4 protein; Norgestrel inhibits the reaction [[Dexamethasone co-treated with Rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of FABP4 protein]
|
CTD |
PMID:29782964 |
|
NCBI chr 2:93,488,251...93,492,961
Ensembl chr 2:93,488,271...93,492,972
|
|
| G
|
Ins2
|
insulin 2
|
multiple interactions
|
ISO
|
[Norgestrel co-treated with Rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of FABP4 protein; Norgestrel inhibits the reaction [[Dexamethasone co-treated with Rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of and results in increased secretion of ADIPOQ protein]; Norgestrel inhibits the reaction [[Dexamethasone co-treated with Rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of FABP4 protein]
|
CTD |
PMID:29782964 |
|
NCBI chr 1:207,272,738...207,421,998
Ensembl chr 1:207,272,742...207,273,805
|
|
| G
|
Klk1c10
|
kallikrein 1-related peptidase C10
|
increases expression
|
ISO
|
Norgestrel results in increased expression of KLK3 protein
|
CTD |
PMID:11580929 |
|
NCBI chr 1:94,402,993...94,407,052
Ensembl chr 1:103,539,527...103,543,586
|
|
| G
|
Nr1i2
|
nuclear receptor subfamily 1, group I, member 2
|
multiple interactions
|
ISO
|
Norgestrel binds to and results in increased activity of NR1I2 protein
|
CTD |
PMID:33049310 |
|
NCBI chr11:75,965,717...76,006,733
Ensembl chr11:75,965,632...76,002,380
|
|
|
|
| G
|
Ackr3
|
atypical chemokine receptor 3
|
decreases expression
|
ISO
|
Prednisolone results in decreased expression of ACKR3 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 9:90,799,682...90,811,246
Ensembl chr 9:98,246,605...98,260,214
|
|
| G
|
Acsl1
|
acyl-CoA synthetase long-chain family member 1
|
increases expression
|
ISO
|
Prednisolone results in increased expression of ACSL1 mRNA
|
CTD |
PMID:17379860 |
|
NCBI chr16:52,487,870...52,554,110
Ensembl chr16:52,487,870...52,554,023
|
|
| G
|
Adora2a
|
adenosine A2a receptor
|
decreases expression
|
ISO
|
Prednisolone results in decreased expression of ADORA2A mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr20:13,315,270...13,332,802
Ensembl chr20:13,315,270...13,332,802
|
|
| G
|
Ahr
|
aryl hydrocarbon receptor
|
increases activity
|
ISO
|
Prednisolone results in increased activity of AHR protein
|
CTD |
PMID:30203046 |
|
NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:57,961,423...57,998,901
|
|
| G
|
Akr1b7
|
aldo-keto reductase family 1, member B7
|
multiple interactions
|
EXP
|
Prednisolone inhibits the reaction [Freund's Adjuvant results in increased expression of AKR1B7 mRNA]
|
CTD |
PMID:21149847 |
|
NCBI chr 4:64,043,901...64,083,751
Ensembl chr 4:64,020,686...64,064,909
|
|
| G
|
Alb
|
albumin
|
increases expression decreases secretion multiple interactions
|
ISO EXP
|
Prednisolone results in increased expression of ALB protein Prednisolone results in decreased secretion of ALB protein montelukast inhibits the reaction [Prednisolone results in decreased secretion of ALB protein]
|
CTD |
PMID:3404815 PMID:30276927 |
|
NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,891,582...17,911,865
|
|
| G
|
Amigo2
|
adhesion molecule with Ig like domain 2
|
decreases expression
|
ISO
|
Prednisolone results in decreased expression of AMIGO2 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 7:130,270,639...130,273,735
Ensembl chr 7:130,270,554...130,282,218
|
|
| G
|
Antxr1
|
ANTXR cell adhesion molecule 1
|
increases expression
|
ISO
|
Prednisolone results in increased expression of ANTXR1 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 4:121,148,102...121,335,549
Ensembl chr 4:121,148,103...121,336,892
|
|
| G
|
Aox1
|
aldehyde oxidase 1
|
increases expression
|
ISO
|
Prednisolone results in increased expression of AOX1 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 9:67,073,831...67,152,980
Ensembl chr 9:67,073,821...67,152,980
|
|
| G
|
Ar
|
androgen receptor
|
multiple interactions increases expression
|
ISO
|
Prednisolone binds to and results in decreased activity of AR protein; Prednisolone binds to and results in increased activity of AR protein; Prednisolone binds to and results in increased activity of AR protein mutant form [Phenytoin co-treated with Prednisolone] results in increased expression of AR protein Prednisolone results in increased expression of AR mRNA; Prednisolone results in increased expression of AR protein
|
CTD |
PMID:11956172 PMID:19490052 PMID:25752796 |
|
NCBI chr X:67,135,317...67,304,476
Ensembl chr X:67,135,317...67,304,467
|
|
| G
|
Arhgap45
|
Rho GTPase activating protein 45
|
decreases expression
|
ISO
|
Prednisolone results in decreased expression of ARHGAP45 mRNA
|
CTD |
PMID:21621594 |
|
NCBI chr 7:9,674,873...9,690,286
Ensembl chr 7:10,325,539...10,341,890
|
|
| G
|
Arrdc3
|
arrestin domain containing 3
|
increases expression
|
ISO
|
Prednisolone results in increased expression of ARRDC3 mRNA
|
CTD |
PMID:24356939 |
|
NCBI chr 2:12,873,202...12,885,716
Ensembl chr 2:12,873,202...12,885,875
|
|
| G
|
Asns
|
asparagine synthetase (glutamine-hydrolyzing)
|
decreases expression
|
ISO
|
Prednisolone results in decreased expression of ASNS mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 4:36,752,061...36,769,970
Ensembl chr 4:36,751,802...36,776,050
|
|
| G
|
Bcl2a1
|
BCL2-related protein A1
|
decreases expression
|
ISO
|
Prednisolone results in decreased expression of BCL2A1 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 8:98,596,806...98,604,890
Ensembl chr 8:98,596,650...98,604,890
|
|
| G
|
Bmal1
|
basic helix-loop-helix ARNT like 1
|
increases expression
|
ISO
|
Prednisolone results in increased expression of BMAL1 mRNA
|
CTD |
PMID:16269518 |
|
NCBI chr 1:176,766,222...176,864,741
Ensembl chr 1:176,829,305...176,864,739
|
|
| G
|
Bst2
|
bone marrow stromal cell antigen 2
|
decreases expression
|
ISO
|
Prednisolone results in decreased expression of BST2 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr16:18,250,593...18,254,967
Ensembl chr16:18,251,847...18,254,967
|
|
| G
|
Casp3
|
caspase 3
|
increases expression multiple interactions
|
EXP
|
Prednisolone results in increased expression of CASP3 protein montelukast inhibits the reaction [Prednisolone results in increased expression of CASP3 protein]
|
CTD |
PMID:30276927 |
|
NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
|
|
| G
|
Cat
|
catalase
|
decreases activity multiple interactions
|
EXP
|
Prednisolone results in decreased activity of CAT protein [Prednisolone co-treated with pirfenidone] inhibits the reaction [Paraquat results in decreased activity of CAT protein]; montelukast inhibits the reaction [Prednisolone results in decreased activity of CAT protein]
|
CTD |
PMID:28921394 PMID:30276927 |
|
NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526
|
|
| G
|
Cbll1
|
Cbl proto-oncogene like 1
|
decreases expression
|
ISO
|
Prednisolone results in decreased expression of CBLL1 mRNA
|
CTD |
PMID:21621594 |
|
NCBI chr 6:48,071,190...48,086,174
Ensembl chr 6:53,798,712...53,813,880
|
|
| G
|
Ccl11
|
C-C motif chemokine ligand 11
|
multiple interactions
|
ISO
|
Prednisolone inhibits the reaction [Dinitrochlorobenzene results in increased expression of CCL11 mRNA]
|
CTD |
PMID:23133493 |
|
NCBI chr10:67,028,328...67,032,929
Ensembl chr10:67,525,862...67,530,575
|
|
| G
|
Ccl2
|
C-C motif chemokine ligand 2
|
decreases expression multiple interactions
|
ISO
|
Prednisolone results in decreased expression of CCL2 protein Prednisolone inhibits the reaction [Dinitrochlorobenzene results in increased expression of CCL2 mRNA] Prednisolone inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of CCL2 protein]
|
CTD |
PMID:20116850 PMID:23133493 PMID:36416909 |
|
NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875
|
|
| G
|
Ccl20
|
C-C motif chemokine ligand 20
|
decreases expression
|
ISO
|
Prednisolone results in decreased expression of CCL20 mRNA; Prednisolone results in decreased expression of CCL20 protein
|
CTD |
PMID:19192274 |
|
NCBI chr 9:91,837,139...91,839,736
Ensembl chr 9:91,836,946...91,839,736
|
|
| G
|
Ccl3
|
C-C motif chemokine ligand 3
|
increases expression multiple interactions
|
ISO
|
Prednisolone results in increased expression of CCL3 protein Prednisolone inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of CCL3 protein]
|
CTD |
PMID:20116850 PMID:36416909 |
|
NCBI chr10:68,948,889...68,950,439
Ensembl chr10:68,948,889...68,950,439
|
|
| G
|
Ccl4
|
C-C motif chemokine ligand 4
|
increases expression
|
ISO
|
Prednisolone results in increased expression of CCL4 protein
|
CTD |
PMID:20116850 |
|
NCBI chr10:68,963,893...68,965,728
Ensembl chr10:68,950,289...68,965,722
|
|
| G
|
Ccn1
|
cellular communication network factor 1
|
increases expression
|
ISO
|
Prednisolone results in increased expression of CCN1 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 2:237,222,730...237,225,689
Ensembl chr 2:237,222,432...237,225,883
|
|
| G
|
Ccn2
|
cellular communication network factor 2
|
increases expression
|
ISO
|
Prednisolone results in increased expression of CCN2 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 1:22,621,498...22,624,614
Ensembl chr 1:22,621,501...22,624,976
|
|
| G
|
Ccn5
|
cellular communication network factor 5
|
increases expression
|
ISO
|
Prednisolone results in increased expression of CCN5 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 3:172,910,670...172,922,064
Ensembl chr 3:172,910,681...172,922,062
|
|
| G
|
Ccng2
|
cyclin G2
|
increases expression
|
ISO
|
Prednisolone results in increased expression of CCNG2 mRNA
|
CTD |
PMID:24356939 |
|
NCBI chr14:15,088,694...15,097,190
Ensembl chr14:15,088,695...15,096,206
|
|
| G
|
Ccr3
|
C-C motif chemokine receptor 3
|
multiple interactions
|
ISO
|
Prednisolone inhibits the reaction [Dinitrochlorobenzene results in increased expression of CCR3 mRNA]
|
CTD |
PMID:23133493 |
|
NCBI chr 8:123,586,100...123,634,178
Ensembl chr 8:132,463,788...132,511,593
|
|
| G
|
Cd34
|
CD34 molecule
|
multiple interactions
|
ISO
|
[Melphalan co-treated with Prednisolone] results in decreased expression of CD34 protein
|
CTD |
PMID:10618687 |
|
NCBI chr13:106,480,313...106,500,844
Ensembl chr13:109,008,623...109,029,315
|
|
| G
|
Cd84
|
CD84 molecule
|
increases expression
|
ISO
|
Prednisolone results in increased expression of CD84 mRNA
|
CTD |
PMID:24356939 |
|
NCBI chr13:86,859,979...86,899,984
Ensembl chr13:86,859,990...86,894,318
|
|
| G
|
Clgn
|
calmegin
|
decreases expression
|
ISO
|
Prednisolone results in decreased expression of CLGN mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr19:41,601,568...41,633,207
Ensembl chr19:41,601,568...41,633,325
|
|
| G
|
Col1a1
|
collagen type I alpha 1 chain
|
increases expression
|
ISO
|
Prednisolone results in increased expression of COL1A1 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr10:80,380,458...80,397,461
Ensembl chr10:80,380,453...80,397,460
|
|
| G
|
Crh
|
corticotropin releasing hormone
|
decreases expression multiple interactions
|
EXP
|
Prednisolone results in decreased expression of CRH protein sairei-to inhibits the reaction [Prednisolone results in decreased expression of CRH protein]
|
CTD |
PMID:9625448 |
|
NCBI chr 2:104,059,184...104,061,048
Ensembl chr 2:104,058,770...104,061,386
|
|
| G
|
Crim1
|
cysteine rich transmembrane BMP regulator 1
|
increases expression
|
ISO
|
Prednisolone results in increased expression of CRIM1 mRNA
|
CTD |
PMID:24356939 |
|
NCBI chr 6:22,447,983...22,622,459
Ensembl chr 6:22,449,948...22,622,416
|
|
| G
|
Cry1
|
cryptochrome circadian regulator 1
|
decreases expression
|
ISO
|
Prednisolone results in decreased expression of CRY1 mRNA
|
CTD |
PMID:16269518 |
|
NCBI chr 7:20,417,526...20,481,791
Ensembl chr 7:20,417,107...20,481,822
|
|
| G
|
Cxcl1
|
C-X-C motif chemokine ligand 1
|
decreases expression
|
ISO
|
Prednisolone results in decreased expression of CXCL1 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr14:17,477,542...17,479,321
Ensembl chr14:17,477,549...17,479,811
|
|
| G
|
Cxcl2
|
C-X-C motif chemokine ligand 2
|
decreases expression
|
ISO
|
Prednisolone results in decreased expression of CXCL2 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr14:17,465,210...17,467,255
Ensembl chr14:17,465,242...17,467,255
|
|
| G
|
Cxcl3
|
C-X-C motif chemokine ligand 3
|
decreases expression
|
ISO
|
Prednisolone results in decreased expression of CXCL1 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr14:17,571,900...17,573,624
Ensembl chr14:17,571,900...17,573,624
|
|
| G
|
Cxcr2
|
C-X-C motif chemokine receptor 2
|
decreases expression
|
ISO
|
Prednisolone results in decreased expression of CXCR2 protein
|
CTD |
PMID:15804745 |
|
NCBI chr 9:83,178,645...83,185,017
Ensembl chr 9:83,183,808...83,188,602
|
|
| G
|
Cxcr4
|
C-X-C motif chemokine receptor 4
|
decreases expression
|
ISO
|
Prednisolone results in decreased expression of CXCR4 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr13:42,630,383...42,634,288
Ensembl chr13:42,630,104...42,634,459
|
|
| G
|
Cyp2c6
|
cytochrome P450, family 2, subfamily C, polypeptide 6
|
multiple interactions
|
EXP
|
Prednisolone inhibits the reaction [Freund's Adjuvant results in decreased expression of CYP2C19 mRNA]
|
CTD |
PMID:21149847 |
|
NCBI chr 1:247,879,058...247,916,804
Ensembl chr 1:247,879,078...247,916,798
|
|
| G
|
Cyp2s1
|
cytochrome P450, family 2, subfamily s, polypeptide 1
|
decreases expression
|
ISO
|
Prednisolone results in decreased expression of CYP2S1 mRNA
|
CTD |
PMID:22155357 |
|
NCBI chr 1:90,437,741...90,453,073
Ensembl chr 1:90,438,224...90,453,073
|
|
| G
|
Cyp3a2
|
cytochrome P450, family 3, subfamily a, polypeptide 2
|
increases expression
|
ISO
|
Prednisolone results in increased expression of CYP3A4 mRNA
|
CTD |
PMID:12673034 |
|
NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857
|
|
| G
|
Dbp
|
D-box binding PAR bZIP transcription factor
|
decreases expression
|
ISO
|
Prednisolone results in decreased expression of DBP mRNA
|
CTD |
PMID:16269518 |
|
NCBI chr 1:105,312,256...105,317,205
Ensembl chr 1:105,312,108...105,317,205
|
|
| G
|
Dio2
|
iodothyronine deiodinase 2
|
increases expression
|
ISO
|
Prednisolone results in increased expression of DIO2 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 6:109,665,523...109,679,809
Ensembl chr 6:115,396,308...115,410,594
|
|
| G
|
Efemp1
|
EGF containing fibulin extracellular matrix protein 1
|
increases expression
|
ISO
|
Prednisolone results in increased expression of EFEMP1 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr14:106,811,769...106,890,961
Ensembl chr14:106,802,304...106,892,808
|
|
| G
|
Fbln1
|
fibulin 1
|
increases expression
|
ISO
|
Prednisolone results in increased expression of FBLN1 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 7:118,190,347...118,269,965
Ensembl chr 7:118,190,478...118,269,965
|
|
| G
|
Fmo2
|
flavin containing dimethylaniline monoxygenase 2
|
increases expression
|
ISO
|
Prednisolone results in increased expression of FMO2 mRNA
|
CTD |
PMID:21621594 |
|
NCBI chr13:77,755,131...77,777,597
Ensembl chr13:77,757,629...77,777,534
|
|
| G
|
Gbp1
|
guanylate binding protein 1
|
decreases expression
|
ISO
|
Prednisolone results in decreased expression of GBP1 mRNA
|
CTD |
PMID:19192274 PMID:21621594 |
|
NCBI chr 2:234,071,366...234,106,012
Ensembl chr 2:234,190,708...234,206,802 Ensembl chr 2:234,190,708...234,206,802
|
|
| G
|
Gdf5
|
growth differentiation factor 5
|
decreases expression
|
ISO
|
Prednisolone results in decreased expression of GDF5 mRNA
|
CTD |
PMID:18830904 |
|
NCBI chr 3:164,914,401...164,918,593
Ensembl chr 3:164,914,401...164,918,593
|
|
| G
|
Gjb1
|
gap junction protein, beta 1
|
increases expression
|
ISO
|
Prednisolone results in increased expression of GJB1 mRNA
|
CTD |
PMID:21621594 |
|
NCBI chr X:66,501,848...66,509,783
Ensembl chr X:70,541,862...70,549,843
|
|
| G
|
Gm2a
|
ganglioside GM2 activator
|
increases expression
|
ISO
|
Prednisolone results in increased expression of GM2A mRNA
|
CTD |
PMID:17379860 |
|
NCBI chr10:39,719,919...39,732,452
Ensembl chr10:39,719,938...39,732,451
|
|
| G
|
Gpm6b
|
glycoprotein m6b
|
increases expression
|
ISO
|
Prednisolone results in increased expression of GPM6B mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr X:31,689,485...31,836,199
Ensembl chr X:31,690,359...31,733,272
|
|
| G
|
Gsdme
|
gasdermin E
|
decreases expression
|
ISO
|
Prednisolone results in decreased expression of GSDME mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 4:80,590,344...80,651,943
Ensembl chr 4:80,588,614...80,641,525
|
|
| G
|
Herc6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
decreases expression
|
ISO
|
Prednisolone results in decreased expression of HERC6 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 4:88,854,612...88,897,043
Ensembl chr 4:88,854,640...88,896,993
|
|
| G
|
Hmgcs1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1
|
increases expression
|
ISO
|
Prednisolone results in increased expression of HMGCS1 mRNA
|
CTD |
PMID:24356939 |
|
NCBI chr 2:53,379,457...53,399,807
Ensembl chr 2:53,382,643...53,399,802
|
|
| G
|
Hpgd
|
15-hydroxyprostaglandin dehydrogenase
|
multiple interactions
|
ISO
|
Prednisolone results in increased expression of and results in increased activity of HPGD protein
|
CTD |
PMID:15680906 |
|
NCBI chr16:38,996,876...39,034,831
Ensembl chr16:38,996,876...39,034,831
|
|
| G
|
Hsd11b1
|
hydroxysteroid 11-beta dehydrogenase 1
|
decreases expression
|
ISO
|
Prednisolone results in decreased expression of HSD11B1 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr13:107,277,526...107,327,462
Ensembl chr13:107,257,239...107,327,432
|
|
| G
|
Hsd11b2
|
hydroxysteroid 11-beta dehydrogenase 2
|
increases metabolic processing
|
ISO
|
HSD11B2 protein results in increased metabolism of Prednisolone
|
CTD |
PMID:16549198 |
|
NCBI chr19:50,307,569...50,312,812
Ensembl chr19:50,307,569...50,312,812
|
|
| G
|
Id3
|
inhibitor of DNA binding 3
|
increases expression
|
ISO
|
Prednisolone results in increased expression of ID3 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 5:153,656,253...153,657,860
Ensembl chr 5:153,630,498...153,657,856
|
|
| G
|
Ifi27
|
interferon, alpha-inducible protein 27
|
decreases expression
|
ISO
|
Prednisolone results in decreased expression of IFI27 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 6:128,355,312...128,361,783
Ensembl chr 6:128,355,079...128,361,781
|
|
| G
|
Ifi44
|
interferon-induced protein 44
|
decreases expression
|
ISO
|
Prednisolone results in decreased expression of IFI44 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 2:243,286,050...243,303,869
Ensembl chr 2:243,286,052...243,306,877
|
|
| G
|
Ifi44l
|
interferon-induced protein 44-like
|
decreases expression
|
ISO
|
Prednisolone results in decreased expression of IFI44L mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 2:240,668,742...240,706,425
Ensembl chr 2:243,328,723...243,366,404
|
|
| G
|
Ifih1
|
interferon induced with helicase C domain 1
|
decreases expression
|
ISO
|
Prednisolone results in decreased expression of IFIH1 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 3:67,635,924...67,683,968
Ensembl chr 3:67,637,545...67,683,968
|
|
| G
|
Ifit3
|
interferon-induced protein with tetratricopeptide repeats 3
|
decreases expression
|
ISO
|
Prednisolone results in decreased expression of IFIT3 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 1:241,527,326...241,532,469
Ensembl chr 1:241,526,880...241,532,521
|
|
| G
|
Ifng
|
interferon gamma
|
decreases expression multiple interactions
|
ISO EXP
|
Prednisolone results in decreased expression of IFNG protein Prednisolone results in decreased expression of IFNG mRNA Prednisolone inhibits the reaction [Dinitrochlorobenzene results in increased expression of IFNG mRNA]; Prednisolone inhibits the reaction [Dinitrochlorobenzene results in increased expression of IFNG protein] Prednisolone inhibits the reaction [Amiodarone results in decreased expression of IFNG protein]
|
CTD |
PMID:11043609 PMID:15821026 PMID:23133493 PMID:34590760 |
|
NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216
|
|
| G
|
Igf1
|
insulin-like growth factor 1
|
decreases response to substance increases expression
|
ISO
|
Prednisolone results in decreased susceptibility to IGF1 protein Prednisolone results in increased expression of IGF1 protein
|
CTD |
PMID:16079165 |
|
NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:24,130,137...24,246,764
|
|
| G
|
Ighe
|
immunoglobulin heavy constant epsilon
|
decreases expression
|
ISO
|
Prednisolone results in decreased expression of IGHE protein
|
CTD |
PMID:15821026 |
|
|
|
| G
|
Il10
|
interleukin 10
|
decreases expression decreases secretion decreases expression
|
ISO
|
Prednisolone results in decreased expression of IL10 protein Prednisolone results in decreased secretion of IL10 protein prednisolone decreases expression of IL10 protein in LPS-stimulated human PBMC
|
CTD RGD |
PMID:15821026 PMID:28003376 PMID:10493164 |
RGD:40903016 |
NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580
|
|
| G
|
Il12b
|
interleukin 12B
|
decreases secretion multiple interactions
|
ISO
|
Prednisolone results in decreased secretion of IL12B protein Prednisolone inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of IL12B protein]
|
CTD |
PMID:28003376 PMID:36416909 |
|
NCBI chr10:29,390,300...29,405,194
Ensembl chr10:29,389,905...29,405,194
|
|
| G
|
Il13
|
interleukin 13
|
multiple interactions
|
ISO
|
Prednisolone inhibits the reaction [Dinitrochlorobenzene results in increased expression of IL13 protein]
|
CTD |
PMID:23133493 |
|
NCBI chr10:38,290,926...38,293,483
Ensembl chr10:38,290,926...38,293,483
|
|
| G
|
Il17a
|
interleukin 17A
|
multiple interactions
|
ISO
|
Prednisolone inhibits the reaction [Dinitrochlorobenzene results in increased expression of IL17A mRNA]
|
CTD |
PMID:23133493 |
|
NCBI chr 9:30,640,844...30,644,331
Ensembl chr 9:30,640,844...30,644,331
|
|
| G
|
Il18
|
interleukin 18
|
multiple interactions
|
ISO
|
Prednisolone inhibits the reaction [Picryl Chloride results in increased expression of IL18 protein]
|
CTD |
PMID:16442096 |
|
NCBI chr 8:59,802,072...59,829,275
Ensembl chr 8:59,809,592...59,831,286
|
|
| G
|
Il1b
|
interleukin 1 beta
|
multiple interactions decreases expression decreases secretion decreases expression
|
ISO EXP
|
Prednisolone inhibits the reaction [Picryl Chloride results in increased expression of IL1B protein] Prednisolone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein] Prednisolone results in decreased expression of IL1B mRNA Prednisolone results in decreased secretion of IL1B protein Prednisolone inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein] prednisolone decreases expression of IL1b mRNA and protein in LPS-stimulated human PBMC
|
CTD RGD |
PMID:9259316 PMID:16442096 PMID:17379860 PMID:22119283 PMID:10493164 |
RGD:40903016 |
NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
|
|
| G
|
Il1rn
|
interleukin 1 receptor antagonist
|
decreases expression
|
ISO
|
Prednisolone results in decreased expression of IL1RN mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 3:27,509,836...27,525,738
Ensembl chr 3:27,509,798...27,525,732
|
|
| G
|
Il2
|
interleukin 2
|
decreases expression
|
ISO
|
Prednisolone results in decreased expression of IL2 protein
|
CTD |
PMID:15821026 |
|
NCBI chr 2:121,932,968...121,937,672
Ensembl chr 2:121,932,968...121,937,672
|
|
| G
|
Il23a
|
interleukin 23 subunit alpha
|
decreases expression
|
ISO
|
Prednisolone results in decreased expression of IL23A mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 7:1,306,320...1,308,434
Ensembl chr 7:1,306,320...1,308,434
|
|
| G
|
Il4
|
interleukin 4
|
multiple interactions decreases expression
|
ISO EXP
|
Prednisolone inhibits the reaction [Dinitrochlorobenzene results in increased expression of IL4 mRNA]; Prednisolone inhibits the reaction [Dinitrochlorobenzene results in increased expression of IL4 protein]; Prednisolone inhibits the reaction [Picryl Chloride results in increased expression of IL4 protein] Prednisolone results in decreased expression of IL4 protein Prednisolone inhibits the reaction [Amiodarone results in increased expression of IL4 protein]
|
CTD |
PMID:15821026 PMID:16442096 PMID:23133493 PMID:34590760 |
|
NCBI chr10:38,272,003...38,277,549
Ensembl chr10:38,272,003...38,277,549
|
|
| G
|
Il5
|
interleukin 5
|
decreases expression multiple interactions
|
ISO
|
Prednisolone results in decreased expression of IL5 protein Prednisolone inhibits the reaction [Dinitrochlorobenzene results in increased expression of IL5 mRNA]
|
CTD |
PMID:15821026 PMID:23133493 |
|
NCBI chr10:38,375,132...38,378,003
Ensembl chr10:38,375,132...38,378,003
|
|
| G
|
Il6
|
interleukin 6
|
multiple interactions decreases expression decreases expression
|
ISO EXP
|
Prednisolone inhibits the reaction [Amiodarone results in increased secretion of IL6 protein] Prednisolone inhibits the reaction [Picryl Chloride results in increased expression of IL6 protein] Prednisolone results in decreased expression of IL6 mRNA Prednisolone results in decreased expression of IL6 mRNA; Prednisolone results in decreased expression of IL6 protein prednisolone decreases expression of IL6 mRNA and protein in LPS-stimulated human PBMC Prednisolone inhibits the reaction [Amiodarone results in increased expression of IL6 protein]
|
CTD RGD |
PMID:11043609 PMID:11288978 PMID:16442096 PMID:19192274 PMID:34590760 PMID:10493164 More...
|
RGD:40903016 |
NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
|
|
| G
|
Irf7
|
interferon regulatory factor 7
|
decreases expression
|
ISO
|
Prednisolone results in decreased expression of IRF7 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 1:205,796,956...205,800,543
Ensembl chr 1:205,796,959...205,800,023
|
|
| G
|
Isg15
|
ISG15 ubiquitin-like modifier
|
decreases expression
|
ISO
|
Prednisolone results in decreased expression of ISG15 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 5:172,066,369...172,067,656
Ensembl chr 5:172,066,369...172,067,656
|
|
| G
|
Isg20
|
interferon stimulated exonuclease gene 20
|
decreases expression
|
ISO
|
Prednisolone results in decreased expression of ISG20 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 1:142,234,729...142,246,403
Ensembl chr 1:142,236,137...142,246,401
|
|
| G
|
Jun
|
Jun proto-oncogene, AP-1 transcription factor subunit
|
multiple interactions
|
EXP
|
Prednisolone inhibits the reaction [Amiodarone results in increased phosphorylation of JUN protein]
|
CTD |
PMID:34590760 |
|
NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:114,973,151...115,013,285
|
|
| G
|
Klhl24
|
kelch-like family member 24
|
increases expression
|
ISO
|
Prednisolone results in increased expression of KLHL24 mRNA
|
CTD |
PMID:24356939 |
|
NCBI chr11:94,348,024...94,382,085
Ensembl chr11:94,351,157...94,382,050
|
|
| G
|
Kmt2a
|
lysine methyltransferase 2A
|
decreases response to substance
|
ISO
|
KMT2A gene mutant form results in decreased susceptibility to Prednisolone
|
CTD |
PMID:14712291 |
|
NCBI chr 8:45,116,763...45,193,320
Ensembl chr 8:54,013,547...54,089,317
|
|
| G
|
Krt8
|
keratin 8
|
increases expression
|
ISO
|
Prednisolone results in increased expression of KRT8 mRNA
|
CTD |
PMID:21621594 |
|
NCBI chr 7:135,002,886...135,010,339
Ensembl chr 7:135,002,894...135,010,403
|
|
| G
|
Lamb3
|
laminin subunit beta 3
|
decreases expression
|
ISO
|
Prednisolone results in decreased expression of LAMB3 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr13:107,362,514...107,404,081
Ensembl chr13:107,322,526...107,404,081
|
|
| G
|
Lcn2
|
lipocalin 2
|
decreases secretion
|
ISO
|
Prednisolone results in decreased secretion of LCN2 protein
|
CTD |
PMID:28003376 |
|
NCBI chr 3:36,078,432...36,081,851
Ensembl chr 3:36,078,436...36,081,842
|
|
| G
|
Ltf
|
lactotransferrin
|
decreases expression
|
ISO
|
Prednisolone results in decreased expression of LTF mRNA
|
CTD |
PMID:21621594 |
|
NCBI chr 8:110,999,948...111,022,795
Ensembl chr 8:119,878,344...119,901,189
|
|
| G
|
Ly6e
|
lymphocyte antigen 6 family member E
|
decreases expression
|
ISO
|
Prednisolone results in decreased expression of LY6E mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 7:108,815,970...108,820,444
Ensembl chr 7:108,816,887...108,820,443
|
|
| G
|
Ly96
|
lymphocyte antigen 96
|
decreases expression
|
ISO
|
Prednisolone results in decreased expression of LY96 mRNA
|
CTD |
PMID:17379860 |
|
NCBI chr 5:2,582,233...2,612,357
Ensembl chr 5:7,365,557...7,395,816
|
|
| G
|
Mapk1
|
mitogen activated protein kinase 1
|
multiple interactions
|
EXP
|
Prednisolone inhibits the reaction [Amiodarone results in increased phosphorylation of MAPK1 protein]
|
CTD |
PMID:34590760 |
|
NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825
|
|
| G
|
Mapk14
|
mitogen activated protein kinase 14
|
multiple interactions
|
EXP
|
Prednisolone inhibits the reaction [Amiodarone results in increased phosphorylation of MAPK14 protein]
|
CTD |
PMID:34590760 |
|
NCBI chr20:6,751,288...6,812,294
Ensembl chr20:6,751,357...6,812,294
|
|
| G
|
Mapk3
|
mitogen activated protein kinase 3
|
multiple interactions
|
EXP
|
Prednisolone inhibits the reaction [Amiodarone results in increased phosphorylation of MAPK3 protein]
|
CTD |
PMID:34590760 |
|
NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411
|
|
| G
|
Marcks
|
myristoylated alanine rich protein kinase C substrate
|
decreases expression
|
ISO
|
Prednisolone results in decreased expression of MARCKS mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr20:42,240,185...42,245,882
Ensembl chr20:42,240,185...42,245,882
|
|
| G
|
Met
|
MET proto-oncogene, receptor tyrosine kinase
|
decreases expression
|
ISO
|
Prednisolone results in decreased expression of MET mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 4:46,756,823...46,864,041
Ensembl chr 4:46,756,506...46,870,821
|
|
| G
|
Mmp10
|
matrix metallopeptidase 10
|
decreases expression
|
ISO
|
Prednisolone results in decreased expression of MMP10 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 8:12,974,707...12,982,613
Ensembl chr 8:12,974,707...12,982,613
|
|
| G
|
Mmp12
|
matrix metallopeptidase 12
|
decreases expression
|
ISO
|
Prednisolone results in decreased expression of MMP12 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 8:4,581,785...4,591,687
Ensembl chr 8:12,866,641...12,884,478
|
|
| G
|
Mmp2
|
matrix metallopeptidase 2
|
multiple interactions
|
EXP
|
pirfenidone promotes the reaction [Prednisolone inhibits the reaction [Paraquat results in increased expression of MMP2 mRNA]]; Prednisolone inhibits the reaction [Paraquat results in increased expression of MMP2 mRNA]
|
CTD |
PMID:28921394 |
|
NCBI chr19:30,327,643...30,355,856
Ensembl chr19:30,327,643...30,355,856
|
|
| G
|
Mmp9
|
matrix metallopeptidase 9
|
multiple interactions
|
EXP
|
Prednisolone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of and results in increased cleavage of MMP9 protein]
|
CTD |
PMID:22119283 |
|
NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442
|
|
| G
|
Mpo
|
myeloperoxidase
|
multiple interactions
|
ISO EXP
|
Prednisolone inhibits the reaction [Picryl Chloride results in increased activity of MPO protein] Prednisolone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]
|
CTD |
PMID:16442096 PMID:22119283 |
|
NCBI chr10:72,594,883...72,608,862
Ensembl chr10:73,092,400...73,102,056
|
|
| G
|
Muc16
|
mucin 16, cell surface associated
|
decreases expression
|
ISO
|
Prednisolone results in decreased expression of MUC16 protein
|
CTD |
PMID:12169874 |
|
NCBI chr 8:16,164,531...16,323,126
|
|
| G
|
Mx1
|
MX dynamin like GTPase 1
|
decreases expression
|
ISO
|
Prednisolone results in decreased expression of MX1 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr11:50,269,056...50,294,699
Ensembl chr11:50,269,057...50,292,904
|
|
| G
|
Ndufa4l2
|
NDUFA4, mitochondrial complex associated like 2
|
decreases expression
|
ISO
|
Prednisolone results in decreased expression of NDUFA4L2 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 7:65,242,169...65,244,296
Ensembl chr 7:65,242,135...65,244,277
|
|
| G
|
Nfe2l2
|
NFE2 like bZIP transcription factor 2
|
increases activity
|
ISO
|
Prednisolone results in increased activity of NFE2L2 protein
|
CTD |
PMID:30203046 |
|
NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090
|
|
| G
|
Nid2
|
nidogen 2
|
increases expression
|
ISO
|
Prednisolone results in increased expression of NID2 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr15:4,507,224...4,562,949
Ensembl chr15:4,506,756...4,562,949
|
|
| G
|
Nmb
|
neuromedin B
|
decreases expression
|
ISO
|
Prednisolone results in decreased expression of NMB mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 1:144,278,678...144,290,523
Ensembl chr 1:144,278,453...144,281,422
|
|
| G
|
Nos2
|
nitric oxide synthase 2
|
increases expression multiple interactions
|
EXP
|
Prednisolone results in increased expression of NOS2 protein montelukast inhibits the reaction [Prednisolone results in increased expression of NOS2 protein]
|
CTD |
PMID:30276927 |
|
NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880
|
|
| G
|
Nr1d1
|
nuclear receptor subfamily 1, group D, member 1
|
decreases expression
|
ISO
|
Prednisolone results in decreased expression of NR1D1 mRNA
|
CTD |
PMID:16269518 |
|
NCBI chr10:84,224,599...84,231,812
Ensembl chr10:84,224,540...84,231,812
|
|
| G
|
Nr3c1
|
nuclear receptor subfamily 3, group C, member 1
|
affects response to substance multiple interactions affects binding increases activity
|
ISO
|
NR3C1 protein alternative form affects the susceptibility to Prednisolone NR3C1 protein alternative form inhibits the reaction [Prednisolone results in increased activity of NR3C1 protein alternative form]; Prednisolone binds to and results in increased activity of NR3C1 protein Prednisolone binds to NR3C1 protein
|
CTD |
PMID:11956172 PMID:14694204 PMID:15362971 PMID:15704223 PMID:15705660 PMID:15755863 More...
|
|
NCBI chr18:31,522,783...31,644,508
Ensembl chr18:31,522,783...31,643,843
|
|
| G
|
Nr3c2
|
nuclear receptor subfamily 3, group C, member 2
|
increases activity
|
ISO
|
Prednisolone results in increased activity of NR3C2 protein
|
CTD |
PMID:15362971 |
|
NCBI chr19:47,619,853...47,964,089
Ensembl chr19:47,619,853...47,964,078
|
|
| G
|
Nr4a3
|
nuclear receptor subfamily 4, group A, member 3
|
decreases expression
|
ISO
|
Prednisolone results in decreased expression of NR4A3 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 5:67,157,141...67,198,287
Ensembl chr 5:67,157,375...67,198,285
|
|
| G
|
Oas1a
|
2'-5' oligoadenylate synthetase 1A
|
decreases expression
|
ISO
|
Prednisolone results in decreased expression of OAS1 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr12:41,330,423...41,341,130
Ensembl chr12:41,285,211...41,341,128
|
|
| G
|
Oasl
|
2'-5'-oligoadenylate synthetase-like
|
decreases expression
|
ISO
|
Prednisolone results in decreased expression of OASL mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr12:47,343,551...47,356,509
Ensembl chr12:47,343,551...47,356,483
|
|
| G
|
Olfml2b
|
olfactomedin-like 2B
|
increases expression
|
ISO
|
Prednisolone results in increased expression of OLFML2B mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr13:85,402,151...85,439,342
Ensembl chr13:85,402,169...85,439,342
|
|
| G
|
Pck1
|
phosphoenolpyruvate carboxykinase 1
|
increases expression
|
ISO
|
Prednisolone results in increased expression of PCK1 mRNA
|
CTD |
PMID:20065017 |
|
NCBI chr 3:182,348,572...182,354,521
Ensembl chr 3:182,348,572...182,354,561
|
|
| G
|
Pdcd4
|
programmed cell death 4
|
increases expression
|
ISO
|
Prednisolone results in increased expression of PDCD4 mRNA
|
CTD |
PMID:24356939 |
|
NCBI chr 1:262,912,659...262,949,581
Ensembl chr 1:262,926,656...262,950,189
|
|
| G
|
Pdlim1
|
PDZ and LIM domain 1
|
increases expression
|
ISO
|
Prednisolone results in increased expression of PDLIM1 mRNA
|
CTD |
PMID:17379860 |
|
NCBI chr 1:248,991,818...249,040,409
Ensembl chr 1:248,991,818...249,047,379
|
|
| G
|
Per1
|
period circadian regulator 1
|
increases expression
|
ISO
|
Prednisolone results in increased expression of PER1 mRNA; Prednisolone results in increased expression of PER1 protein
|
CTD |
PMID:16269518 |
|
NCBI chr10:54,299,002...54,313,804
Ensembl chr10:54,302,641...54,314,211
|
|
| G
|
Per2
|
period circadian regulator 2
|
decreases expression
|
ISO
|
Prednisolone results in decreased expression of PER2 mRNA
|
CTD |
PMID:16269518 |
|
NCBI chr 9:99,454,828...99,497,069
Ensembl chr 9:99,454,830...99,496,993
|
|
| G
|
Phgdh
|
phosphoglycerate dehydrogenase
|
decreases expression
|
ISO
|
Prednisolone results in decreased expression of PHGDH mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 2:188,595,700...188,624,789
Ensembl chr 2:188,595,700...188,624,789
|
|
| G
|
Pilra
|
paired immunoglobin-like type 2 receptor alpha
|
decreases expression
|
ISO
|
Prednisolone results in decreased expression of PILRA mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr12:23,452,626...23,464,772
|
|
| G
|
Pla1a
|
phospholipase A1 member A
|
multiple interactions
|
ISO
|
Prednisolone inhibits the reaction [Lipopolysaccharides results in increased expression of PLA1A mRNA]
|
CTD |
PMID:20573295 |
|
NCBI chr11:62,320,112...62,357,779
Ensembl chr11:75,825,585...75,878,165
|
|
| G
|
Pla2g4a
|
phospholipase A2 group 4A
|
multiple interactions
|
ISO
|
Prednisolone inhibits the reaction [Lipopolysaccharides results in increased expression of PLA2G4A mRNA]
|
CTD |
PMID:20573295 |
|
NCBI chr13:64,427,921...64,572,352
Ensembl chr13:64,427,916...64,589,641
|
|
| G
|
Plcl1
|
phospholipase C-like 1
|
increases expression
|
ISO
|
Prednisolone results in increased expression of PLCL1 mRNA
|
CTD |
PMID:24356939 |
|
NCBI chr 9:64,395,976...64,733,171
Ensembl chr 9:64,361,520...64,733,171
|
|
| G
|
Plpp3
|
phospholipid phosphatase 3
|
decreases expression
|
ISO
|
Prednisolone results in decreased expression of PLPP3 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 5:125,156,000...125,231,119
Ensembl chr 5:125,155,945...125,235,667
|
|
| G
|
Pomc
|
proopiomelanocortin
|
decreases expression multiple interactions
|
EXP
|
Prednisolone results in decreased expression of POMC protein; Prednisolone results in decreased expression of POMC protein modified form sairei-to inhibits the reaction [Prednisolone results in decreased expression of POMC protein modified form]
|
CTD |
PMID:9625448 PMID:14694204 |
|
NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:32,659,346...32,665,173
|
|
| G
|
Ppp1r14a
|
protein phosphatase 1, regulatory (inhibitor) subunit 14A
|
multiple interactions
|
EXP
|
Prednisolone inhibits the reaction [Acetylcholine results in increased phosphorylation of PPP1R14A protein]
|
CTD |
PMID:18577381 |
|
NCBI chr 1:93,708,269...93,718,218
Ensembl chr 1:93,708,218...93,719,147
|
|
| G
|
Prelp
|
proline and arginine rich end leucine rich repeat protein
|
increases expression
|
ISO
|
Prednisolone results in increased expression of PRELP mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr13:45,368,407...45,391,480
Ensembl chr13:47,922,590...47,932,324
|
|
| G
|
Prlr
|
prolactin receptor
|
multiple interactions
|
EXP
|
Prednisolone inhibits the reaction [Freund's Adjuvant results in increased expression of PRLR mRNA]
|
CTD |
PMID:21149847 |
|
NCBI chr 2:60,861,391...61,051,883
Ensembl chr 2:60,861,658...61,051,882
|
|
| G
|
Ptgs2
|
prostaglandin-endoperoxide synthase 2
|
decreases expression
|
ISO
|
Prednisolone results in decreased expression of PTGS2 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320
|
|
| G
|
Rdh16
|
retinol dehydrogenase 16
|
multiple interactions
|
EXP
|
Prednisolone inhibits the reaction [Freund's Adjuvant results in decreased expression of RDH2 mRNA]
|
CTD |
PMID:21149847 |
|
NCBI chr 7:65,499,763...65,510,304
|
|
| G
|
Rgs4
|
regulator of G-protein signaling 4
|
multiple interactions decreases expression
|
EXP ISO
|
Prednisolone inhibits the reaction [Freund's Adjuvant results in increased expression of RGS4 mRNA] Prednisolone results in decreased expression of RGS4 mRNA
|
CTD |
PMID:19192274 PMID:21149847 |
|
NCBI chr13:84,469,593...84,475,884
Ensembl chr13:84,469,593...84,475,884
|
|
| G
|
Rhoa
|
ras homolog family member A
|
multiple interactions
|
EXP
|
Prednisolone inhibits the reaction [[[Antigens, Bacterial co-treated with Allergens] results in increased expression of and results in increased activity of RHOA protein] which results in increased susceptibility to Acetylcholine]; Prednisolone inhibits the reaction [[Antigens, Bacterial co-treated with Allergens] results in increased expression of and results in increased activity of RHOA protein]; Prednisolone inhibits the reaction [[Antigens, Bacterial co-treated with Allergens] results in increased expression of RHOA mRNA]
|
CTD |
PMID:18391481 |
|
NCBI chr 8:117,870,548...117,904,303
Ensembl chr 8:117,870,270...117,904,302
|
|
| G
|
Rig1
|
RNA sensor RIG-1
|
decreases expression
|
ISO
|
Prednisolone results in decreased expression of RIGI mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 5:55,321,351...55,369,947
Ensembl chr 5:60,117,398...60,165,995
|
|
| G
|
Ripk2
|
receptor-interacting serine-threonine kinase 2
|
decreases expression
|
ISO
|
Prednisolone results in decreased expression of RIPK2 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 5:29,630,806...29,662,804
Ensembl chr 5:34,428,573...34,459,663
|
|
| G
|
Rnf19b
|
ring finger protein 19B
|
decreases expression
|
ISO
|
Prednisolone results in decreased expression of RNF19B mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 5:141,406,085...141,431,376
Ensembl chr 5:146,690,577...146,714,394
|
|
| G
|
Rsad2
|
radical S-adenosyl methionine domain containing 2
|
decreases expression
|
ISO
|
Prednisolone results in decreased expression of RSAD2 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 6:48,774,985...48,788,245
Ensembl chr 6:48,774,985...48,788,320
|
|
| G
|
Scg2
|
secretogranin II
|
multiple interactions
|
EXP
|
Prednisolone inhibits the reaction [Freund's Adjuvant results in increased expression of SCG2 mRNA]
|
CTD |
PMID:21149847 |
|
NCBI chr 9:80,803,074...80,808,646
Ensembl chr 9:88,251,354...88,269,598
|
|
| G
|
Slc22a8
|
solute carrier family 22 member 8
|
multiple interactions
|
EXP
|
Prednisolone inhibits the reaction [Freund's Adjuvant results in decreased expression of SLC22A8 mRNA]
|
CTD |
PMID:21149847 |
|
NCBI chr 1:214,925,506...214,945,516
Ensembl chr 1:214,925,508...214,946,588
|
|
| G
|
Slc43a3
|
solute carrier family 43, member 3
|
decreases expression
|
ISO
|
Prednisolone results in decreased expression of SLC43A3 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 3:90,414,822...90,450,654
Ensembl chr 3:90,415,977...90,436,976
|
|
| G
|
Slc7a11
|
solute carrier family 7 member 11
|
increases expression decreases expression
|
ISO
|
Prednisolone results in increased expression of SLC7A11 mRNA Prednisolone results in decreased expression of SLC7A11 mRNA
|
CTD |
PMID:19192274 PMID:24356939 |
|
NCBI chr 2:136,532,912...136,668,560
Ensembl chr 2:136,532,246...136,695,695
|
|
| G
|
Slc7a8
|
solute carrier family 7 member 8
|
increases expression
|
ISO
|
Prednisolone results in increased expression of SLC7A8 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr15:32,153,016...32,212,715
Ensembl chr15:32,153,018...32,212,715
|
|
| G
|
Sms
|
spermine synthase
|
decreases expression
|
ISO
|
Prednisolone results in decreased expression of SMS mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr X:41,331,693...41,387,713
Ensembl chr X:41,331,799...41,387,712
|
|
| G
|
Sod2
|
superoxide dismutase 2
|
decreases expression
|
ISO
|
Prednisolone results in decreased expression of SOD2 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:50,043,325...50,050,168
|
|
| G
|
Sox9
|
SRY-box transcription factor 9
|
decreases expression
|
ISO
|
Prednisolone results in decreased expression of SOX9 mRNA
|
CTD |
PMID:17379860 |
|
NCBI chr10:98,305,744...98,311,250
Ensembl chr10:98,305,744...98,311,250
|
|
| G
|
Srsf7
|
serine and arginine rich splicing factor 7
|
decreases expression
|
ISO
|
Prednisolone results in decreased expression of SRSF7 mRNA
|
CTD |
PMID:21621594 |
|
NCBI chr 6:20,564,035...20,571,205
Ensembl chr 6:20,564,044...20,571,212
|
|
| G
|
Srxn1
|
sulfiredoxin 1
|
increases expression
|
ISO
|
Prednisolone results in increased expression of SRXN1 mRNA
|
CTD |
PMID:24356939 |
|
NCBI chr 3:161,064,812...161,070,372
Ensembl chr 3:161,059,931...161,088,765
|
|
| G
|
Stat4
|
signal transducer and activator of transcription 4
|
decreases expression
|
ISO
|
Prednisolone results in decreased expression of STAT4 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 9:49,472,660...49,588,540
Ensembl chr 9:56,911,523...57,077,346
|
|
| G
|
Sts
|
steroid sulfatase
|
increases expression
|
ISO
|
Prednisolone results in increased expression of STS mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr X:46,102,524...46,110,868
Ensembl chr X:46,102,548...46,111,104
|
|
| G
|
Sult2a2
|
sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 2
|
multiple interactions
|
EXP
|
Prednisolone inhibits the reaction [Freund's Adjuvant results in increased expression of SULT2A2 mRNA]
|
CTD |
PMID:21149847 |
|
NCBI chr 1:75,909,585...75,976,600
Ensembl chr 1:84,962,100...85,104,511
|
|
| G
|
Tafa5
|
TAFA chemokine like family member 5
|
increases expression
|
ISO
|
Prednisolone results in increased expression of TAFA5 mRNA
|
CTD |
PMID:21621594 |
|
NCBI chr 7:120,493,447...120,714,720
Ensembl chr 7:120,493,060...120,714,718
|
|
| G
|
Tat
|
tyrosine aminotransferase
|
multiple interactions increases activity increases expression
|
EXP ISO
|
(3b,5b,7a,12a)-7,12-dihydroxy-3-(2-((4-((11b,17b)-17-hydroxy-3-oxo-17-prop-1-ynylestra-4,9-dien-11-yl) phenyl)(methyl)amino)ethoxy)cholan-24-oic acid inhibits the reaction [Prednisolone results in increased activity of TAT protein]; (3b,5b,7a,12a)-7,12-dihydroxy-3-(2-((4-((11b,17b)-17-hydroxy-3-oxo-17-prop-1-ynylestra-4,9-dien-11-yl) phenyl)(methyl)amino)ethoxy)cholan-24-oic acid inhibits the reaction [Prednisolone results in increased expression of TAT mRNA]
|
CTD |
PMID:9259316 PMID:14694204 PMID:15784656 |
|
NCBI chr19:54,856,604...54,867,168
Ensembl chr19:54,856,563...54,867,482
|
|
| G
|
Tex261
|
testis expressed 261
|
decreases expression
|
ISO
|
Prednisolone results in decreased expression of TEX261 mRNA
|
CTD |
PMID:21621594 |
|
NCBI chr 4:116,253,547...116,260,730
Ensembl chr 4:117,811,176...117,819,180
|
|
| G
|
Tf
|
transferrin
|
increases expression
|
ISO
|
Prednisolone results in increased expression of TF protein
|
CTD |
PMID:3404815 |
|
NCBI chr 8:112,668,667...112,695,376
Ensembl chr 8:112,647,642...112,695,400
|
|
| G
|
Tfpi2
|
tissue factor pathway inhibitor 2
|
decreases expression
|
ISO
|
Prednisolone results in decreased expression of TFPI2 mRNA
|
CTD |
PMID:17379860 |
|
NCBI chr 4:32,936,462...32,941,385
Ensembl chr 4:32,936,854...32,941,426
|
|
| G
|
Tgfb1
|
transforming growth factor, beta 1
|
decreases expression multiple interactions
|
ISO EXP
|
Prednisolone results in decreased expression of TGFB1 protein pirfenidone promotes the reaction [Prednisolone inhibits the reaction [Paraquat results in increased expression of TGFB1 mRNA]]; Prednisolone inhibits the reaction [Paraquat results in increased expression of TGFB1 mRNA]
|
CTD |
PMID:11728950 PMID:28921394 |
|
NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899
|
|
| G
|
Thbs1
|
thrombospondin 1
|
increases expression
|
ISO
|
Prednisolone results in increased expression of THBS1 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 3:125,510,250...125,525,402
Ensembl chr 3:125,510,250...125,525,402
|
|
| G
|
Timp1
|
TIMP metallopeptidase inhibitor 1
|
multiple interactions
|
EXP
|
pirfenidone promotes the reaction [Prednisolone inhibits the reaction [Paraquat results in increased expression of TIMP1 mRNA]]; Prednisolone inhibits the reaction [Paraquat results in increased expression of TIMP1 mRNA]
|
CTD |
PMID:28921394 |
|
NCBI chr X:3,766,509...3,772,578
Ensembl chr X:3,766,510...3,771,135
|
|
| G
|
Tlr2
|
toll-like receptor 2
|
decreases expression
|
ISO
|
Prednisolone results in decreased expression of TLR2 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 2:171,499,189...171,504,831
Ensembl chr 2:171,497,060...171,520,194
|
|
| G
|
Tnf
|
tumor necrosis factor
|
increases expression decreases expression multiple interactions decreases expression
|
ISO EXP
|
Prednisolone results in increased expression of TNF mRNA Prednisolone results in decreased expression of TNF mRNA [pirfenidone co-treated with Prednisolone] inhibits the reaction [Paraquat results in increased expression of TNF mRNA]; Prednisolone inhibits the reaction [Amiodarone results in increased expression of TNF protein]; Prednisolone inhibits the reaction [Paraquat results in increased expression of TNF mRNA]; Prednisolone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein] Prednisolone inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of TNF protein] prednisolone decreases expression of TNFa mRNA and protein in LPS-stimulated human PBMC Prednisolone inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of TNF protein]
|
CTD RGD |
PMID:11043609 PMID:19233868 PMID:20054000 PMID:22119283 PMID:28921394 PMID:34590760 PMID:36416909 PMID:10493164 More...
|
RGD:40903016 |
NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
|
|
| G
|
Tnfaip2
|
TNF alpha induced protein 2
|
decreases expression
|
ISO
|
Prednisolone results in decreased expression of TNFAIP2 mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 6:130,476,832...130,489,914
Ensembl chr 6:136,298,082...136,311,106
|
|
| G
|
Trim63
|
tripartite motif containing 63
|
increases expression
|
ISO
|
Prednisolone results in increased expression of TRIM63 mRNA
|
CTD |
PMID:20065017 |
|
NCBI chr 5:151,817,209...151,831,026
Ensembl chr 5:151,817,225...151,831,058
|
|
| G
|
Txnip
|
thioredoxin interacting protein
|
increases expression
|
ISO
|
Prednisolone results in increased expression of TXNIP mRNA
|
CTD |
PMID:19192274 |
|
NCBI chr 2:186,781,933...186,785,736
Ensembl chr 2:186,781,163...186,785,731
|
|
| G
|
Vegfa
|
vascular endothelial growth factor A
|
decreases expression
|
ISO
|
Prednisolone results in decreased expression of VEGFA protein
|
CTD |
PMID:20116850 |
|
NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194
|
|
| G
|
Vldlr
|
very low density lipoprotein receptor
|
increases expression
|
ISO
|
Prednisolone results in increased expression of VLDLR mRNA
|
CTD |
PMID:24356939 |
|
NCBI chr 1:234,239,769...234,272,150
Ensembl chr 1:234,240,121...234,272,154
|
|
| G
|
Xist
|
X inactive specific transcript
|
decreases expression
|
ISO
|
Prednisolone results in decreased expression of XIST mRNA
|
CTD |
PMID:17379860 |
|
NCBI chr X:68,474,987...68,492,500
|
|
|
|
| G
|
A2m
|
alpha-2-macroglobulin
|
affects expression decreases expression
|
ISO
|
Progesterone affects the expression of A2M mRNA Progesterone results in decreased expression of A2M mRNA
|
CTD |
PMID:17251523 PMID:22238285 |
|
NCBI chr 4:156,570,163...156,619,870
Ensembl chr 4:156,569,860...156,619,868
|
|
| G
|
Aamp
|
angio-associated, migratory cell protein
|
increases expression
|
ISO
|
Progesterone results in increased expression of AAMP mRNA
|
CTD |
PMID:18497975 |
|
NCBI chr 9:75,863,382...75,869,188
Ensembl chr 9:83,312,519...83,318,325
|
|
| G
|
Aard
|
alanine and arginine rich domain containing protein
|
increases expression
|
ISO
|
Progesterone results in increased expression of AARD mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 7:83,364,478...83,369,319
Ensembl chr 7:85,253,992...85,259,163
|
|
| G
|
Abat
|
4-aminobutyrate aminotransferase
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in increased expression of ABAT mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr10:7,503,351...7,599,474
Ensembl chr10:7,492,022...7,599,474
|
|
| G
|
Abca6
|
ATP binding cassette subfamily A member 6
|
increases expression
|
ISO
|
Progesterone results in increased expression of ABCA6 mRNA
|
CTD |
PMID:21795739 |
|
NCBI chr10:95,642,026...95,711,535
Ensembl chr10:95,641,900...95,710,899
|
|
| G
|
Abca8
|
ATP binding cassette subfamily A member 8
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of ABCA8 mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr10:95,416,984...95,490,647
Ensembl chr10:95,416,205...95,490,452
|
|
| G
|
Abcb11
|
ATP binding cassette subfamily B member 11
|
multiple interactions decreases activity
|
ISO
|
Progesterone inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid] Progesterone results in decreased activity of ABCB11 protein
|
CTD |
PMID:24014644 |
|
NCBI chr 3:74,424,620...74,520,646
Ensembl chr 3:74,424,979...74,520,581
|
|
| G
|
Abcb1a
|
ATP binding cassette subfamily B member 1A
|
multiple interactions increases expression
|
ISO
|
Dactinomycin inhibits the reaction [Progesterone results in increased expression of ABCB1 mRNA]; Dactinomycin inhibits the reaction [Progesterone results in increased expression of ABCB1 protein] Progesterone results in increased expression of ABCB1 mRNA; Progesterone results in increased expression of ABCB1 protein
|
CTD |
PMID:15290871 PMID:19813763 |
|
NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:26,312,409...26,397,135
|
|
| G
|
Abcb1b
|
ATP-binding cassette, sub-family B member 1B
|
increases expression
|
EXP
|
Progesterone results in increased expression of ABCB1B mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr 4:26,197,706...26,280,156
Ensembl chr 4:26,106,903...26,279,567
|
|
| G
|
Abcb9
|
ATP binding cassette subfamily B member 9
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of ABCB9 mRNA
|
CTD |
PMID:21540246 |
|
NCBI chr12:38,146,659...38,192,862
Ensembl chr12:38,159,904...38,192,860
|
|
| G
|
Abcc2
|
ATP binding cassette subfamily C member 2
|
decreases activity
|
ISO
|
Progesterone results in decreased activity of ABCC2 protein
|
CTD |
PMID:16049127 |
|
NCBI chr 1:252,613,875...252,672,459
Ensembl chr 1:252,614,017...252,673,471
|
|
| G
|
Abcc3
|
ATP binding cassette subfamily C member 3
|
multiple interactions decreases expression increases expression
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of ABCC3 mRNA Progesterone results in decreased expression of ABCC3 mRNA Progesterone results in increased expression of ABCC3 mRNA
|
CTD |
PMID:17404688 PMID:21795739 PMID:22238285 |
|
NCBI chr10:79,793,571...79,839,528
Ensembl chr10:79,793,583...79,839,494
|
|
| G
|
Abcc4
|
ATP binding cassette subfamily C member 4
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of ABCC4 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr15:101,948,387...102,182,912
Ensembl chr15:101,949,433...102,181,375
|
|
| G
|
Abcc6
|
ATP binding cassette subfamily C member 6
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of ABCC6 mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr 1:105,583,681...105,637,895
Ensembl chr 1:105,583,682...105,637,895
|
|
| G
|
Abcc9
|
ATP binding cassette subfamily C member 9
|
increases expression
|
ISO EXP
|
Progesterone results in increased expression of ABCC9 mRNA
|
CTD |
PMID:20726854 PMID:20864642 |
|
NCBI chr 4:177,262,848...177,386,837
Ensembl chr 4:177,262,848...177,386,348
|
|
| G
|
Abcd1
|
ATP binding cassette subfamily D member 1
|
affects expression
|
ISO
|
Progesterone affects the expression of ABCD1 mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr X:156,579,669...156,601,448
Ensembl chr X:156,579,785...156,601,446
|
|
| G
|
Abcd3
|
ATP binding cassette subfamily D member 3
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of ABCD3 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 2:212,536,791...212,590,379
Ensembl chr 2:212,536,791...212,590,504
|
|
| G
|
Abcg1
|
ATP binding cassette subfamily G member 1
|
increases expression decreases expression multiple interactions
|
ISO EXP
|
Progesterone results in increased expression of ABCG1 mRNA Progesterone results in decreased expression of ABCG1 mRNA [Estradiol co-treated with Progesterone] results in decreased expression of ABCG1 mRNA
|
CTD |
PMID:18070364 PMID:20660070 PMID:20726854 PMID:21540246 |
|
NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,127,803...9,186,563
|
|
| G
|
Abcg2
|
ATP binding cassette subfamily G member 2
|
affects expression decreases activity multiple interactions
|
ISO
|
Progesterone affects the expression of ABCG2 Progesterone results in decreased activity of ABCG2 protein Progesterone inhibits the reaction [ABCG2 protein results in increased uptake of estrone sulfate]; Progesterone inhibits the reaction [Estradiol results in increased expression of ABCG2]
|
CTD |
PMID:16849015 PMID:18086804 PMID:22581381 |
|
NCBI chr 4:89,006,056...89,132,915
Ensembl chr 4:89,005,969...89,132,493
|
|
| G
|
Abcg5
|
ATP binding cassette subfamily G member 5
|
multiple interactions
|
ISO
|
Progesterone results in decreased activity of [ABCG5 protein binds to ABCG8 protein]
|
CTD |
PMID:17055487 |
|
NCBI chr 6:15,717,936...15,743,376
Ensembl chr 6:15,717,936...15,743,376
|
|
| G
|
Abcg8
|
ATP binding cassette subfamily G member 8
|
multiple interactions
|
ISO
|
Progesterone results in decreased activity of [ABCG5 protein binds to ABCG8 protein]
|
CTD |
PMID:17055487 |
|
NCBI chr 6:9,945,629...9,964,912
Ensembl chr 6:15,698,448...15,717,730
|
|
| G
|
Abhd11
|
abhydrolase domain containing 11
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of ABHD11 mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr12:21,682,206...21,685,331
Ensembl chr12:27,318,749...27,321,970
|
|
| G
|
Abhd12
|
abhydrolase domain containing 12, lysophospholipase
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of ABHD12 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 3:139,659,315...139,719,529
Ensembl chr 3:160,119,724...160,179,969
|
|
| G
|
Abhd5
|
abhydrolase domain containing 5, lysophosphatidic acid acyltransferase
|
increases expression
|
ISO
|
Progesterone results in increased expression of ABHD5 mRNA
|
CTD |
PMID:20864642 |
|
NCBI chr 8:130,877,834...130,903,947
Ensembl chr 8:130,877,703...130,903,947
|
|
| G
|
Abi3bp
|
ABI family member 3 binding protein
|
increases expression
|
ISO
|
Progesterone results in increased expression of ABI3BP mRNA
|
CTD |
PMID:20864642 |
|
NCBI chr11:43,912,187...44,128,888
Ensembl chr11:57,381,422...57,598,120
|
|
| G
|
Ablim1
|
actin-binding LIM protein 1
|
multiple interactions increases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of ABLIM1 mRNA Progesterone results in increased expression of ABLIM1 mRNA
|
CTD |
PMID:20660070 PMID:20864642 |
|
NCBI chr 1:256,083,747...256,372,075
Ensembl chr 1:266,088,870...266,377,098
|
|
| G
|
Ablim2
|
actin binding LIM protein family, member 2
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of ABLIM2 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr14:79,090,046...79,214,986
Ensembl chr14:79,090,923...79,214,972
|
|
| G
|
Acadl
|
acyl-CoA dehydrogenase, long chain
|
increases expression
|
EXP
|
Progesterone results in increased expression of ACADL mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr 9:75,783,689...75,822,077
Ensembl chr 9:75,783,689...75,822,164
|
|
| G
|
Acan
|
aggrecan
|
increases expression
|
ISO
|
Progesterone results in increased expression of ACAN protein
|
CTD |
PMID:20673848 |
|
NCBI chr 1:132,981,582...133,044,416
Ensembl chr 1:142,390,951...142,453,779
|
|
| G
|
Acat2
|
acetyl-CoA acetyltransferase 2
|
increases expression
|
ISO
|
Progesterone results in increased expression of ACAT2 mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr 1:50,100,840...50,118,886
Ensembl chr 1:50,100,817...50,135,095
|
|
| G
|
Acbd7
|
acyl-CoA binding domain containing 7
|
increases expression
|
ISO
|
Progesterone results in increased expression of ACBD7 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr17:79,813,106...79,821,254
Ensembl chr17:79,813,106...79,818,448
|
|
| G
|
Ackr4
|
atypical chemokine receptor 4
|
increases expression decreases expression
|
ISO
|
Progesterone results in increased expression of ACKR4 mRNA Progesterone results in decreased expression of ACKR4 mRNA
|
CTD |
PMID:18070364 PMID:20864642 |
|
NCBI chr 8:113,595,325...113,599,762
Ensembl chr 8:113,595,293...113,602,372
|
|
| G
|
Acod1
|
aconitate decarboxylase 1
|
affects expression increases expression
|
ISO
|
Progesterone affects the expression of ACOD1; Progesterone affects the expression of ACOD1 mRNA Progesterone results in increased expression of ACOD1 mRNA
|
CTD |
PMID:15178747 PMID:17251523 PMID:22238285 |
|
NCBI chr15:86,286,531...86,295,803
Ensembl chr15:86,286,579...86,295,687
|
|
| G
|
Acot7
|
acyl-CoA thioesterase 7
|
affects expression
|
ISO
|
Progesterone affects the expression of ACOT7 mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr 5:167,969,284...168,062,033
Ensembl chr 5:167,968,895...168,062,033
|
|
| G
|
Acot9
|
acyl-CoA thioesterase 9
|
affects expression
|
ISO
|
Progesterone affects the expression of ACOT9 mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr X:43,922,943...43,973,311
Ensembl chr X:43,914,923...43,973,205
|
|
| G
|
Acp3
|
acid phosphatase 3
|
multiple interactions decreases expression
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of ACP3 mRNA; Progesterone inhibits the reaction [Estradiol results in increased expression of ACP3 mRNA] Progesterone results in decreased expression of ACP3 mRNA
|
CTD |
PMID:17404688 PMID:21795739 |
|
NCBI chr 8:113,784,372...113,833,033
Ensembl chr 8:113,785,032...113,833,033
|
|
| G
|
Acsl1
|
acyl-CoA synthetase long-chain family member 1
|
multiple interactions increases expression
|
ISO EXP
|
[Estradiol co-treated with Progesterone] results in increased expression of ACSL1 mRNA; [Progesterone co-treated with Estradiol] results in increased expression of ACSL1 mRNA Progesterone results in increased expression of ACSL1 mRNA
|
CTD |
PMID:17404688 PMID:20660070 PMID:20726854 PMID:20864642 PMID:21795739 |
|
NCBI chr16:52,487,870...52,554,110
Ensembl chr16:52,487,870...52,554,023
|
|
| G
|
Acsm3
|
acyl-CoA synthetase medium-chain family member 3
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of ACSM3 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 1:183,564,652...183,591,328
Ensembl chr 1:183,564,635...183,591,437
|
|
| G
|
Acta1
|
actin, alpha 1, skeletal muscle
|
increases expression
|
EXP ISO
|
Progesterone results in increased expression of ACTA1 mRNA
|
CTD |
PMID:20726854 PMID:22238285 |
|
NCBI chr19:68,781,168...68,784,194
Ensembl chr19:68,781,168...68,786,178
|
|
| G
|
Acta2
|
actin alpha 2, smooth muscle
|
increases expression multiple interactions decreases expression
|
ISO EXP
|
Progesterone results in increased expression of ACTA2 mRNA Progesterone promotes the reaction [Hydrogen Peroxide results in increased expression of ACTA2 protein] Progesterone results in decreased expression of ACTA2 mRNA
|
CTD |
PMID:16284289 PMID:18037150 PMID:20864642 PMID:21540246 |
|
NCBI chr 1:241,159,723...241,172,503
Ensembl chr 1:241,159,724...241,172,503
|
|
| G
|
Actb
|
actin, beta
|
affects expression
|
ISO
|
Progesterone affects the expression of ACTB mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr12:16,776,664...16,779,634
Ensembl chr12:16,776,661...16,780,242
|
|
| G
|
Actc1
|
actin, alpha, cardiac muscle 1
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of ACTC1 mRNA
|
CTD |
PMID:21795739 |
|
NCBI chr 3:121,266,291...121,271,827
Ensembl chr 3:121,266,291...121,271,827
|
|
| G
|
Actg2
|
actin gamma 2, smooth muscle
|
affects expression increases expression
|
ISO
|
Progesterone affects the expression of ACTG2 mRNA Progesterone results in increased expression of ACTG2 mRNA
|
CTD |
PMID:17251523 PMID:20864642 |
|
NCBI chr 4:117,579,513...117,604,379
Ensembl chr 4:117,579,514...117,604,295
|
|
| G
|
Actn1
|
actinin, alpha 1
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of ACTN1 mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr 6:98,998,553...99,093,334
Ensembl chr 6:104,731,485...104,826,172
|
|
| G
|
Acvr1
|
activin A receptor type 1
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of ACVR1 mRNA
|
CTD |
PMID:21795739 |
|
NCBI chr 3:42,978,558...43,097,892
Ensembl chr 3:63,387,381...63,477,884
|
|
| G
|
Acvr2b
|
activin A receptor type 2B
|
affects expression
|
ISO
|
Progesterone affects the expression of ACVR2B mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr 8:119,138,901...119,178,477
Ensembl chr 8:128,016,526...128,048,171
|
|
| G
|
Acy1
|
aminoacylase 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of ACY1 mRNA
|
CTD |
PMID:19693291 |
|
NCBI chr 8:115,951,068...115,956,471
Ensembl chr 8:115,951,068...115,956,405
|
|
| G
|
Ada
|
adenosine deaminase
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of ADA mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 3:172,818,174...172,842,283
Ensembl chr 3:172,818,176...172,842,293
|
|
| G
|
Adam12
|
ADAM metallopeptidase domain 12
|
multiple interactions decreases expression affects expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of ADAM12 mRNA; [Progesterone co-treated with Estradiol] results in decreased expression of ADAM12 mRNA Progesterone results in decreased expression of ADAM12 mRNA Progesterone affects the expression of ADAM12 mRNA
|
CTD |
PMID:17251523 PMID:17404688 PMID:19406945 PMID:21795739 |
|
NCBI chr 1:188,686,984...189,014,206
Ensembl chr 1:198,116,975...198,447,552
|
|
| G
|
Adam17
|
ADAM metallopeptidase domain 17
|
decreases expression multiple interactions
|
ISO
|
Progesterone results in decreased expression of ADAM17 mRNA [Progesterone co-treated with Estradiol] results in decreased expression of ADAM17 mRNA
|
CTD |
PMID:18692832 |
|
NCBI chr 6:46,601,583...46,663,690
Ensembl chr 6:46,601,583...46,649,344
|
|
| G
|
Adam28
|
ADAM metallopeptidase domain 28
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of ADAM28 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr15:43,774,463...43,840,726
Ensembl chr15:50,127,516...50,250,526
|
|
| G
|
Adam8
|
ADAM metallopeptidase domain 8
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of ADAM8 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 1:204,206,206...204,218,988
Ensembl chr 1:204,206,199...204,218,485
|
|
| G
|
Adam9
|
ADAM metallopeptidase domain 9
|
increases expression
|
ISO
|
Progesterone results in increased expression of ADAM9 mRNA
|
CTD |
PMID:21795739 |
|
NCBI chr16:67,022,538...67,101,647
Ensembl chr16:73,725,114...73,804,646
|
|
| G
|
Adamts1
|
ADAM metallopeptidase with thrombospondin type 1 motif, 1
|
multiple interactions increases expression
|
ISO
|
[Progesterone co-treated with Dihydrotestosterone] results in increased expression of ADAMTS1 mRNA; [Progesterone co-treated with Dihydrotestosterone] results in increased expression of ADAMTS1 protein; [Progesterone co-treated with Estradiol] results in increased expression of ADAMTS1 mRNA; Estradiol inhibits the reaction [Progesterone results in increased expression of ADAMTS1 mRNA]; Estradiol inhibits the reaction [Progesterone results in increased expression of ADAMTS1 protein]; Mifepristone inhibits the reaction [Progesterone results in increased expression of ADAMTS1 mRNA]; Mifepristone inhibits the reaction [Progesterone results in increased expression of ADAMTS1 protein] Progesterone results in increased expression of ADAMTS1 mRNA; Progesterone results in increased expression of ADAMTS1 protein
|
CTD |
PMID:17018655 PMID:20226447 PMID:20864642 PMID:21795739 |
|
NCBI chr11:38,418,565...38,427,384
Ensembl chr11:38,418,101...38,427,390
|
|
| G
|
Adamts2
|
ADAM metallopeptidase with thrombospondin type 1 motif, 2
|
increases expression
|
ISO
|
Progesterone results in increased expression of ADAMTS2 mRNA
|
CTD |
PMID:20864642 |
|
NCBI chr10:35,422,030...35,627,483
Ensembl chr10:35,422,030...35,627,483
|
|
| G
|
Adamts20
|
ADAM metallopeptidase with thrombospondin type 1 motif, 20
|
increases expression
|
ISO
|
Progesterone results in increased expression of ADAMTS20 mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr 7:125,396,227...125,528,020
Ensembl chr 7:127,275,538...127,407,296
|
|
| G
|
Adamts8
|
ADAM metallopeptidase with thrombospondin type 1 motif, 8
|
increases expression multiple interactions
|
ISO
|
Progesterone results in increased expression of ADAMTS8 mRNA [Estradiol co-treated with Progesterone] results in increased expression of ADAMTS8 mRNA; [Progesterone co-treated with Estradiol] results in decreased expression of ADAMTS8 mRNA; [Progesterone co-treated with Estradiol] results in increased expression of ADAMTS8 mRNA
|
CTD |
PMID:17404688 PMID:20226447 PMID:20660070 |
|
NCBI chr 8:37,607,001...37,626,597
Ensembl chr 8:37,607,001...37,626,597
|
|
| G
|
Adamts9
|
ADAM metallopeptidase with thrombospondin type 1 motif, 9
|
multiple interactions increases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of ADAMTS9 mRNA Progesterone results in increased expression of ADAMTS9 mRNA
|
CTD |
PMID:20660070 PMID:21540246 |
|
NCBI chr 4:126,847,726...127,019,924
Ensembl chr 4:126,847,729...127,019,876
|
|
| G
|
Adamtsl1
|
ADAMTS-like 1
|
increases expression
|
ISO
|
Progesterone results in increased expression of ADAMTSL1 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 5:99,964,406...100,919,786
Ensembl chr 5:105,010,464...105,964,394
|
|
| G
|
Adap2
|
ArfGAP with dual PH domains 2
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of ADAP2 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr10:65,138,006...65,166,147
Ensembl chr10:65,622,434...65,664,022
|
|
| G
|
Adcy1
|
adenylate cyclase 1
|
increases expression
|
ISO
|
Progesterone results in increased expression of ADCY1 mRNA
|
CTD |
PMID:20864642 |
|
NCBI chr14:86,125,119...86,234,459
Ensembl chr14:86,124,850...86,261,075
|
|
| G
|
Adcy2
|
adenylate cyclase 2
|
multiple interactions
|
EXP
|
[Genistein co-treated with estradiol-17-benzoate co-treated with Progesterone] results in increased expression of ADCY2 protein
|
CTD |
PMID:26529183 |
|
NCBI chr 1:36,204,054...36,650,645
Ensembl chr 1:36,204,054...36,650,645
|
|
| G
|
Adcy5
|
adenylate cyclase 5
|
increases expression
|
EXP
|
Progesterone results in increased expression of ADCY5 mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr11:78,976,861...79,123,343
Ensembl chr11:78,976,861...79,123,343
|
|
| G
|
Adcyap1
|
adenylate cyclase activating polypeptide 1
|
increases abundance
|
ISO
|
ADCYAP1 protein results in increased abundance of Progesterone
|
CTD |
PMID:19926922 |
|
NCBI chr 9:113,102,632...113,122,500
Ensembl chr 9:120,550,328...120,556,383
|
|
| G
|
Adcyap1r1
|
ADCYAP receptor type I
|
multiple interactions
|
ISO
|
ADCYAP1R1 protein promotes the reaction [LHB protein results in increased abundance of Progesterone]
|
CTD |
PMID:19926922 |
|
NCBI chr 4:84,593,558...84,642,700
Ensembl chr 4:85,924,100...85,972,973
|
|
| G
|
Adgrd1
|
adhesion G protein-coupled receptor D1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of ADGRD1 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr12:33,124,981...33,239,778
Ensembl chr12:33,125,915...33,272,509
|
|
| G
|
Adgrg6
|
adhesion G protein-coupled receptor G6
|
increases expression
|
ISO
|
Progesterone results in increased expression of ADGRG6 mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr 1:10,633,004...10,774,685
Ensembl chr 1:10,631,829...10,774,023
|
|
| G
|
Adgrl2
|
adhesion G protein-coupled receptor L2
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of ADGRL2 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 2:237,696,055...238,327,141
Ensembl chr 2:240,356,177...240,855,933
|
|
| G
|
Adh1c
|
alcohol dehydrogenase 1C (class I), gamma polypeptide
|
increases expression
|
ISO
|
Progesterone results in increased expression of ADH1C mRNA
|
CTD |
PMID:20864642 |
|
NCBI chr 2:229,470,703...229,482,291
Ensembl chr 2:229,470,703...229,482,291
|
|
| G
|
Adh5
|
alcohol dehydrogenase 5 (class III), chi polypeptide
|
multiple interactions
|
ISO
|
[Progesterone results in increased activity of PGR protein] which results in increased expression of ADH5 mRNA
|
CTD |
PMID:15845616 |
|
NCBI chr 2:229,648,557...229,660,964
Ensembl chr 2:229,648,501...229,665,232
|
|
| G
|
Adi1
|
acireductone dioxygenase 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of ADI1 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 6:45,306,885...45,313,847
Ensembl chr 6:51,034,931...51,042,855
|
|
| G
|
Adipoq
|
adiponectin, C1Q and collagen domain containing
|
affects expression increases abundance multiple interactions
|
ISO
|
Progesterone affects the expression of ADIPOQ mRNA ADIPOQ protein results in increased abundance of Progesterone ADIPOQ protein promotes the reaction [IGF1 protein results in increased abundance of Progesterone]
|
CTD |
PMID:17251523 PMID:19081562 PMID:27181934 |
|
NCBI chr11:91,226,524...91,240,244
Ensembl chr11:91,226,180...91,240,169
|
|
| G
|
Adipor1
|
adiponectin receptor 1
|
increases expression
|
ISO
|
Progesterone results in increased expression of ADIPOR1 mRNA
|
CTD |
PMID:29603059 |
|
NCBI chr13:48,411,438...48,431,251
Ensembl chr13:48,411,826...48,431,255
|
|
| G
|
Adipor2
|
adiponectin receptor 2
|
multiple interactions increases expression
|
ISO
|
[Progesterone co-treated with Estradiol] results in increased expression of ADIPOR2 mRNA Progesterone results in increased expression of ADIPOR2 mRNA
|
CTD |
PMID:17404688 PMID:29603059 |
|
NCBI chr 4:152,524,604...152,588,848
Ensembl chr 4:154,172,567...154,231,666
|
|
| G
|
Adm
|
adrenomedullin
|
multiple interactions affects abundance
|
ISO EXP
|
ADM protein modified form inhibits the reaction [ADM protein inhibits the reaction [CGA protein results in increased secretion of Progesterone]] ADM protein affects the abundance of Progesterone
|
CTD |
PMID:18401014 PMID:21824440 |
|
NCBI chr 1:174,164,178...174,182,372
Ensembl chr 1:174,178,773...174,182,371
|
|
| G
|
Adora2b
|
adenosine A2B receptor
|
multiple interactions increases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of ADORA2B mRNA Progesterone results in increased expression of ADORA2B mRNA
|
CTD |
PMID:19693291 |
|
NCBI chr10:47,439,712...47,456,092
Ensembl chr10:47,439,701...47,456,091
|
|
| G
|
Adra2a
|
adrenoceptor alpha 2A
|
increases expression
|
ISO
|
Progesterone results in increased expression of ADRA2A mRNA
|
CTD |
PMID:15713686 |
|
NCBI chr 1:263,066,780...263,069,580
Ensembl chr 1:263,065,278...263,069,871
|
|
| G
|
Adra2c
|
adrenoceptor alpha 2C
|
increases expression
|
ISO
|
Progesterone results in increased expression of ADRA2C mRNA
|
CTD |
PMID:20864642 |
|
NCBI chr14:79,695,514...79,697,476
Ensembl chr14:79,694,995...79,706,656
|
|
| G
|
Adrb2
|
adrenoceptor beta 2
|
increases expression
|
EXP
|
Progesterone results in increased expression of ADRB2 mRNA
|
CTD |
PMID:15985637 PMID:20726854 |
|
NCBI chr18:57,912,760...57,914,802
Ensembl chr18:57,911,348...57,914,803
|
|
| G
|
Adrb3
|
adrenoceptor beta 3
|
increases expression
|
ISO
|
Progesterone results in increased expression of ADRB3 mRNA
|
CTD |
PMID:15713686 |
|
NCBI chr16:71,544,603...71,547,410
Ensembl chr16:71,542,567...71,547,420
|
|
| G
|
Afap1l2
|
actin filament associated protein 1-like 2
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of AFAP1L2 mRNA
|
CTD |
PMID:20864642 PMID:21795739 |
|
NCBI chr 1:265,969,368...266,065,951
Ensembl chr 1:265,969,368...266,065,943
|
|
| G
|
Afp
|
alpha-fetoprotein
|
multiple interactions increases response to substance
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of AFP protein AFP protein results in increased susceptibility to Progesterone
|
CTD |
PMID:18497072 PMID:22720075 |
|
NCBI chr14:17,857,584...17,875,645
Ensembl chr14:17,857,584...17,875,649
|
|
| G
|
Agap3
|
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of AGAP3 mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr 4:11,567,191...11,617,610
Ensembl chr 4:11,567,191...11,617,285
|
|
| G
|
Agpat4
|
1-acylglycerol-3-phosphate O-acyltransferase 4
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of AGPAT4 mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr 1:48,525,131...48,633,798
Ensembl chr 1:51,075,081...51,180,976
|
|
| G
|
Agrn
|
agrin
|
increases expression
|
EXP
|
Progesterone results in increased expression of AGRN protein
|
CTD |
PMID:16777347 |
|
NCBI chr 5:172,031,528...172,064,429
Ensembl chr 5:172,031,528...172,064,539
|
|
| G
|
Agt
|
angiotensinogen
|
multiple interactions decreases secretion decreases expression
|
ISO
|
Progesterone inhibits the reaction [AGT protein results in increased abundance of Inositol Phosphates] AGT protein results in decreased secretion of Progesterone Progesterone results in decreased expression of AGT mRNA
|
CTD |
PMID:1337236 PMID:22095930 PMID:28235592 |
|
NCBI chr19:69,426,540...69,447,017
Ensembl chr19:69,421,638...69,446,944
|
|
| G
|
Ahr
|
aryl hydrocarbon receptor
|
affects binding decreases expression multiple interactions affects expression
|
ISO EXP
|
Progesterone binds to AHR protein Progesterone results in decreased expression of AHR mRNA [Progesterone co-treated with Estradiol] affects the expression of AHR mRNA; [Progesterone co-treated with Estradiol] affects the expression of AHR protein Progesterone affects the expression of AHR mRNA; Progesterone affects the expression of AHR protein
|
CTD |
PMID:10478797 PMID:24777823 PMID:32668270 |
|
NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:57,961,423...57,998,901
|
|
| G
|
Ahrr
|
aryl-hydrocarbon receptor repressor
|
affects expression multiple interactions
|
EXP
|
Progesterone affects the expression of AHRR mRNA [Progesterone co-treated with Estradiol] affects the expression of AHRR mRNA
|
CTD |
PMID:24777823 |
|
NCBI chr 1:28,993,634...29,088,673
Ensembl chr 1:30,810,866...30,952,866
|
|
| G
|
Aicda
|
activation-induced cytidine deaminase
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of AICDA mRNA; Progesterone results in decreased expression of AICDA protein
|
CTD |
PMID:19139166 PMID:19553525 |
|
NCBI chr 4:157,446,120...157,455,958
Ensembl chr 4:157,444,697...157,456,356
|
|
| G
|
Aif1
|
allograft inflammatory factor 1
|
multiple interactions
|
EXP
|
[Estradiol co-treated with Progesterone] results in decreased expression of AIF1 protein
|
CTD |
PMID:21277368 |
|
NCBI chr20:3,651,435...3,657,341
Ensembl chr20:3,652,243...3,657,339
|
|
| G
|
Ajap1
|
adherens junctions associated protein 1
|
increases expression
|
ISO
|
Progesterone results in increased expression of AJAP1 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 5:163,907,846...164,021,004
Ensembl chr 5:169,190,477...169,304,515
|
|
| G
|
Ak1
|
adenylate kinase 1
|
increases expression
|
EXP
|
Progesterone results in increased expression of AK1 mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr 3:36,310,113...36,320,760
Ensembl chr 3:36,310,197...36,320,757
|
|
| G
|
Akap1
|
A-kinase anchoring protein 1
|
increases expression
|
EXP
|
Progesterone results in increased expression of AKAP1 mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr10:73,621,021...73,654,123
Ensembl chr10:74,119,124...74,138,190
|
|
| G
|
Akap12
|
A-kinase anchoring protein 12
|
multiple interactions increases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of AKAP12 mRNA Progesterone results in increased expression of AKAP12 mRNA; Progesterone results in increased expression of AKAP12 protein
|
CTD |
PMID:20660070 PMID:21795739 |
|
NCBI chr 1:43,135,515...43,225,245
Ensembl chr 1:43,199,008...43,225,557
|
|
| G
|
Akap13
|
A-kinase anchoring protein 13
|
multiple interactions increases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of AKAP13 mRNA Progesterone results in increased expression of AKAP13 mRNA
|
CTD |
PMID:20660070 PMID:20864642 |
|
NCBI chr 1:129,313,183...129,619,647
Ensembl chr 1:138,724,150...139,029,401
|
|
| G
|
Akap5
|
A-kinase anchoring protein 5
|
increases expression
|
EXP
|
Progesterone results in increased expression of AKAP5 mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr 6:100,787,169...100,796,712
Ensembl chr 6:100,790,148...100,796,620
|
|
| G
|
Akap8
|
A-kinase anchoring protein 8
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of AKAP8 mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr 7:11,966,769...11,983,056
Ensembl chr 7:11,966,772...11,982,900
|
|
| G
|
Akap9
|
A-kinase anchoring protein 9
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of AKAP9 mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr 4:31,011,475...31,147,338
Ensembl chr 4:31,011,475...31,147,338
|
|
| G
|
Akr1b10
|
aldo-keto reductase family 1 member B10
|
multiple interactions decreases expression
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of AKR1B10 mRNA Progesterone results in decreased expression of AKR1B10 mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr 4:64,005,632...64,027,860
Ensembl chr 4:64,007,420...64,020,847
|
|
| G
|
Akr1c1
|
aldo-keto reductase family 1, member C1
|
affects reduction decreases expression multiple interactions increases reduction
|
ISO
|
AKR1C1 protein affects the reduction of Progesterone Progesterone results in decreased expression of AKR1C1 mRNA AKR1C1 protein affects the metabolism of and results in decreased activity of Progesterone AKR1C1 protein results in increased reduction of Progesterone
|
CTD |
PMID:11995921 PMID:12604236 PMID:16338060 PMID:16962702 PMID:22245609 PMID:23183084 More...
|
|
NCBI chr17:70,720,397...70,747,285
Ensembl chr17:70,720,398...70,747,247
|
|
| G
|
Akr1c2
|
aldo-keto reductase family 1, member C2
|
increases reduction
|
ISO
|
AKR1C2 protein results in increased reduction of Progesterone
|
CTD |
PMID:11158055 PMID:22245609 PMID:25463305 |
|
NCBI chr17:70,669,684...70,717,935
Ensembl chr17:70,669,710...70,685,686
|
|
| G
|
Akr1c3
|
aldo-keto reductase family 1, member C3
|
multiple interactions increases metabolic processing affects metabolic processing affects abundance increases reduction increases expression decreases expression
|
ISO EXP
|
[AKR1C3 protein results in increased metabolism of Progesterone] which results in increased chemical synthesis of 20-alpha-Dihydroprogesterone; [AKR1C3 protein results in increased reduction of Progesterone] which results in increased chemical synthesis of 20-alpha-Dihydroprogesterone AKR1C18 protein results in increased metabolism of Progesterone AKR1C18 protein affects the metabolism of Progesterone AKR1C18 protein affects the abundance of Progesterone Progesterone results in increased expression of AKR1C3 mRNA Progesterone results in decreased expression of AKR1C3 mRNA
|
CTD |
PMID:8172618 PMID:15261307 PMID:15471942 PMID:17122075 PMID:19010312 PMID:20036328 PMID:23183084 PMID:25463305 More...
|
|
NCBI chr17:71,020,884...71,037,779
Ensembl chr17:70,970,900...71,048,438
|
|
| G
|
Akr1d1
|
aldo-keto reductase family 1, member D1
|
increases reduction multiple interactions
|
ISO
|
AKR1D1 protein results in increased reduction of Progesterone AKR1D1 protein alternative form results in increased reduction of Progesterone; AKR1D1 protein results in increased reduction of Progesterone [AKR1D1 protein alternative form results in increased reduction of Progesterone] which results in increased chemical synthesis of 5-alpha-Dihydroprogesterone
|
CTD |
PMID:18624455 PMID:30928400 |
|
NCBI chr 4:67,121,288...67,154,543
Ensembl chr 4:67,120,024...67,154,540
|
|
| G
|
Akt1
|
AKT serine/threonine kinase 1
|
multiple interactions increases phosphorylation
|
ISO EXP
|
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Progesterone results in increased phosphorylation of AKT1 protein] [Estradiol co-treated with Progesterone co-treated with Methylnitrosourea] results in increased phosphorylation of AKT1 protein; Mifepristone inhibits the reaction [Progesterone results in increased phosphorylation of AKT1 protein]; Pertussis Toxin inhibits the reaction [Progesterone results in increased phosphorylation of AKT1 protein] Progesterone inhibits the reaction [Estradiol results in increased phosphorylation of AKT1 protein]
|
CTD |
PMID:15358673 PMID:15845746 PMID:22465879 PMID:28324061 |
|
NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610
|
|
| G
|
Alad
|
aminolevulinate dehydratase
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of ALAD mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 5:80,977,562...80,987,901
Ensembl chr 5:80,977,562...80,988,041
|
|
| G
|
Alas1
|
5'-aminolevulinate synthase 1
|
increases expression
|
EXP
|
Progesterone results in increased expression of ALAS1 mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr 8:115,755,238...115,768,642
Ensembl chr 8:115,755,238...115,768,642
|
|
| G
|
Alas2
|
5'-aminolevulinate synthase 2
|
affects expression
|
ISO
|
Progesterone affects the expression of ALAS2 mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr X:22,890,650...22,914,046
Ensembl chr X:22,890,689...22,914,043
|
|
| G
|
Alb
|
albumin
|
multiple interactions
|
ISO
|
[[IL6 protein co-treated with IL1B protein co-treated with TNF protein] affects the susceptibility to [Testosterone co-treated with Estradiol co-treated with Progesterone]] which affects the expression of ALB protein; [[Testosterone co-treated with Estradiol co-treated with Progesterone] affects the susceptibility to [IL6 protein co-treated with IL1B protein co-treated with TNF protein]] which affects the expression of ALB protein
|
CTD |
PMID:20621171 |
|
NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,891,582...17,911,865
|
|
| G
|
Alcam
|
activated leukocyte cell adhesion molecule
|
increases expression
|
ISO
|
Progesterone results in increased expression of ALCAM mRNA
|
CTD |
PMID:18497975 PMID:21795739 |
|
NCBI chr11:61,804,932...62,005,250
Ensembl chr11:61,805,049...62,006,876
|
|
| G
|
Aldh1a1
|
aldehyde dehydrogenase 1 family, member A1
|
affects expression decreases expression multiple interactions
|
ISO
|
Progesterone affects the expression of ALDH1A1 mRNA Progesterone results in decreased expression of ALDH1A1 mRNA [Progesterone results in increased activity of PGR protein] which results in increased expression of ALDH1A1 mRNA
|
CTD |
PMID:15845616 PMID:17251523 PMID:22238285 |
|
NCBI chr 1:227,426,939...227,579,497
Ensembl chr 1:227,427,070...227,579,500
|
|
| G
|
Aldh1a2
|
aldehyde dehydrogenase 1 family, member A2
|
affects expression
|
ISO
|
Progesterone affects the expression of ALDH1A2 mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr 8:80,758,641...80,837,891
Ensembl chr 8:80,758,142...80,837,883
|
|
| G
|
Aldh1a3
|
aldehyde dehydrogenase 1 family, member A3
|
multiple interactions decreases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of ALDH1A3 mRNA Progesterone results in decreased expression of ALDH1A3 mRNA
|
CTD |
PMID:20660070 PMID:22238285 |
|
NCBI chr 1:119,982,272...120,017,416
Ensembl chr 1:129,392,516...129,427,777
|
|
| G
|
Aldh1l1
|
aldehyde dehydrogenase 1 family, member L1
|
increases expression
|
EXP
|
Progesterone results in increased expression of ALDH1L1 mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr 4:124,617,182...124,663,674
Ensembl chr 4:124,617,217...124,664,704
|
|
| G
|
Aldh3a1
|
aldehyde dehydrogenase 3 family, member A1
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of ALDH3A1 mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr10:46,392,464...46,402,151
Ensembl chr10:46,392,411...46,402,151
|
|
| G
|
Aldh3b2
|
aldehyde dehydrogenase 3 family, member B2
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of ALDH3B2 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 1:201,250,260...201,264,699
Ensembl chr 1:210,675,302...210,694,155
|
|
| G
|
Aldh3b3
|
aldehyde dehydrogenase 3 family, member B3
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of ALDH3B2 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 1:201,193,832...201,201,666
Ensembl chr 1:210,622,639...210,629,879
|
|
| G
|
Aldh6a1
|
aldehyde dehydrogenase 6 family, member A1
|
increases expression
|
EXP
|
Progesterone results in increased expression of ALDH6A1 mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr 6:109,809,092...109,829,725
Ensembl chr 6:109,809,122...109,829,743
|
|
| G
|
Aldoc
|
aldolase, fructose-bisphosphate C
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of ALDOC mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr10:63,217,477...63,221,066
Ensembl chr10:63,715,489...63,719,133
|
|
| G
|
Alg2
|
ALG2, alpha-1,3/1,6-mannosyltransferase
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of ALG2 mRNA
|
CTD |
PMID:21453500 |
|
NCBI chr 5:66,564,328...66,568,887
Ensembl chr 5:66,564,330...66,568,887
|
|
| G
|
Alox15
|
arachidonate 15-lipoxygenase
|
affects expression increases expression
|
ISO EXP
|
Progesterone affects the expression of ALOX15 mRNA Progesterone results in increased expression of ALOX15 mRNA
|
CTD |
PMID:17251523 PMID:21770760 |
|
NCBI chr10:55,559,060...55,567,535
Ensembl chr10:55,559,061...55,567,723
|
|
| G
|
Alox15b
|
arachidonate 15-lipoxygenase, type B
|
multiple interactions increases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of ALOX15B mRNA Progesterone results in increased expression of ALOX15B mRNA
|
CTD |
PMID:20660070 PMID:21540246 |
|
NCBI chr10:54,391,331...54,400,648
Ensembl chr10:54,391,302...54,400,648
|
|
| G
|
Alpg
|
alkaline phosphatase, germ cell
|
multiple interactions affects expression
|
ISO
|
perfluorooctanoic acid inhibits the reaction [Progesterone affects the expression of ALPPL2 mRNA]; Progesterone inhibits the reaction [perfluorooctanoic acid inhibits the reaction [Progesterone affects the expression of ALPPL2 mRNA]]
|
CTD |
PMID:31896193 |
|
NCBI chr 9:87,748,721...87,761,500
Ensembl chr 9:95,198,334...95,205,742
|
|
| G
|
Alpl
|
alkaline phosphatase, biomineralization associated
|
multiple interactions decreases expression increases expression increases activity
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of ALPL mRNA; [Progesterone co-treated with Estradiol] results in increased expression of ALPL mRNA; fenvalerate inhibits the reaction [Progesterone results in increased activity of ALPL protein]; Permethrin inhibits the reaction [Progesterone results in increased activity of ALPL protein] Progesterone results in decreased expression of ALPL mRNA Progesterone results in increased expression of ALPL mRNA
|
CTD |
PMID:16326432 PMID:17404688 PMID:20660070 PMID:21540246 |
|
NCBI chr 5:155,234,770...155,289,785
Ensembl chr 5:155,234,775...155,254,167
|
|
| G
|
Alpp
|
alkaline phosphatase, placental
|
multiple interactions increases expression
|
ISO
|
[Progesterone co-treated with Estradiol] results in increased expression of ALPP mRNA Progesterone results in increased expression of ALPP mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr 9:87,765,846...87,768,606
Ensembl chr 9:95,213,374...95,219,451
|
|
| G
|
Amigo2
|
adhesion molecule with Ig like domain 2
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of AMIGO2 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 7:130,270,639...130,273,735
Ensembl chr 7:130,270,554...130,282,218
|
|
| G
|
Amigo3
|
adhesion molecule with Ig like domain 3
|
decreases expression
|
EXP
|
Progesterone results in decreased expression of AMIGO3 mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr 8:108,741,899...108,743,425
Ensembl chr 8:117,616,629...117,626,577
|
|
| G
|
Ammecr1
|
AMMECR nuclear protein 1
|
increases expression
|
ISO
|
Progesterone results in increased expression of AMMECR1 mRNA
|
CTD |
PMID:21795739 |
|
NCBI chr X:111,262,792...111,368,099
Ensembl chr X:111,262,792...111,368,099
|
|
| G
|
Ampd3
|
adenosine monophosphate deaminase 3
|
affects expression
|
ISO
|
Progesterone affects the expression of AMPD3 mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr 1:174,319,526...174,364,605
Ensembl chr 1:174,294,867...174,364,608
|
|
| G
|
Amph
|
amphiphysin
|
increases expression
|
ISO
|
Progesterone results in increased expression of AMPH mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr17:45,739,385...45,982,905
Ensembl chr17:50,435,018...50,678,501
|
|
| G
|
Amy2a5
|
amylase 2a5
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of AMY2A5 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 2:201,261,621...201,270,188
|
|
| G
|
Andpro
|
androgen regulated protein
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of CST4 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 3:157,171,739...157,178,262
Ensembl chr 3:157,171,740...157,178,104
|
|
| G
|
Ang
|
angiogenin
|
increases expression affects expression
|
ISO
|
Progesterone results in increased expression of ANG mRNA Progesterone affects the expression of ANG mRNA
|
CTD |
PMID:17251523 PMID:21795739 |
|
NCBI chr15:24,312,711...24,323,361
Ensembl chr15:26,786,065...26,801,106
|
|
| G
|
Angpt1
|
angiopoietin 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of ANGPT1 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 7:75,415,959...75,668,696
Ensembl chr 7:75,418,218...75,668,696
|
|
| G
|
Angpt2
|
angiopoietin 2
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of ANGPT2 mRNA; [Progesterone co-treated with Estradiol] results in decreased expression of ANGPT2 mRNA
|
CTD |
PMID:17404688 PMID:20660070 |
|
NCBI chr16:77,790,760...77,841,241
Ensembl chr16:77,790,563...77,841,239
|
|
| G
|
Angpt4
|
angiopoietin 4
|
multiple interactions increases expression
|
ISO
|
[Progesterone co-treated with Estrogens] results in increased expression of ANGPT4 mRNA Progesterone results in increased expression of ANGPT4 mRNA
|
CTD |
PMID:22821867 |
|
NCBI chr 3:160,880,539...160,913,923
Ensembl chr 3:160,880,728...160,913,921
|
|
| G
|
Angptl1
|
angiopoietin-like 1
|
multiple interactions increases expression
|
ISO
|
[Progesterone co-treated with Estrogens] results in increased expression of ANGPTL1 mRNA Progesterone results in increased expression of ANGPTL1 mRNA
|
CTD |
PMID:22350948 |
|
NCBI chr13:71,463,913...71,531,810
Ensembl chr13:71,511,727...71,531,818
|
|
| G
|
Angptl2
|
angiopoietin-like 2
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of ANGPTL2 mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr 3:36,914,876...36,944,715
Ensembl chr 3:36,914,745...36,945,876
|
|
| G
|
Angptl3
|
angiopoietin-like 3
|
decreases expression multiple interactions
|
ISO
|
Progesterone results in decreased expression of ANGPTL3 mRNA [Progesterone co-treated with Estrogens] results in decreased expression of ANGPTL3 mRNA
|
CTD |
PMID:22350948 |
|
NCBI chr 5:118,818,494...118,825,531
Ensembl chr 5:118,818,499...118,826,444
|
|
| G
|
Angptl4
|
angiopoietin-like 4
|
increases expression multiple interactions
|
ISO
|
Progesterone results in increased expression of ANGPTL4 mRNA Progesterone inhibits the reaction [Estrogens results in decreased expression of ANGPTL4 mRNA]
|
CTD |
PMID:21795739 PMID:22350948 |
|
NCBI chr 7:15,252,450...15,259,971
Ensembl chr 7:15,252,473...15,258,681
|
|
| G
|
Angptl6
|
angiopoietin-like 6
|
multiple interactions increases expression
|
ISO
|
[Progesterone co-treated with Estrogens] results in increased expression of ANGPTL6 mRNA Progesterone results in increased expression of ANGPTL6 mRNA
|
CTD |
PMID:22350948 |
|
NCBI chr 8:27,689,804...27,696,172
Ensembl chr 8:27,689,806...27,696,111
|
|
| G
|
Angptl7
|
angiopoietin like 7
|
increases expression
|
ISO
|
Progesterone results in increased expression of ANGPTL7 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 5:164,215,223...164,220,408
Ensembl chr 5:164,215,223...164,220,584
|
|
| G
|
Ank3
|
ankyrin 3
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of ANK3 mRNA
|
CTD |
PMID:21540246 |
|
NCBI chr20:18,601,307...19,224,790
Ensembl chr20:18,601,826...19,084,879
|
|
| G
|
Ankh
|
ANKH inorganic pyrophosphate transport regulator
|
affects expression
|
ISO
|
Progesterone affects the expression of ANK mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr 2:79,883,350...80,011,222
Ensembl chr 2:79,883,544...80,011,699
|
|
| G
|
Ankrd22
|
ankyrin repeat domain 22
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of ANKRD22 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 1:231,639,035...231,670,537
Ensembl chr 1:241,052,237...241,105,559
|
|
| G
|
Ankrd35
|
ankyrin repeat domain 35
|
multiple interactions decreases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of ANKRD35 mRNA Progesterone results in decreased expression of ANKRD35 mRNA
|
CTD |
PMID:20660070 PMID:21540246 |
|
NCBI chr 2:184,207,076...184,227,063
Ensembl chr 2:186,895,945...186,915,902
|
|
| G
|
Ankrd50
|
ankyrin repeat domain containing 50
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of ANKRD50 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 2:121,466,275...121,500,758
Ensembl chr 2:123,396,606...123,427,340
|
|
| G
|
Ankrd55
|
ankyrin repeat domain 55
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in increased expression of ANKRD55 mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr 2:45,617,011...45,717,086
Ensembl chr 2:45,617,177...45,717,057
|
|
| G
|
Anln
|
anillin, actin binding protein
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of ANLN mRNA
|
CTD |
PMID:21795739 |
|
NCBI chr 8:29,134,222...29,197,513
Ensembl chr 8:29,134,222...29,197,513
|
|
| G
|
Ano9
|
anoctamin 9
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of ANO9 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 1:196,208,863...196,230,381
Ensembl chr 1:205,638,572...205,659,489
|
|
| G
|
Antxr1
|
ANTXR cell adhesion molecule 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of ANTXR1 mRNA; [Progesterone co-treated with Estradiol] results in increased expression of ANTXR1 mRNA
|
CTD |
PMID:17404688 PMID:20660070 |
|
NCBI chr 4:121,148,102...121,335,549
Ensembl chr 4:121,148,103...121,336,892
|
|
| G
|
Antxr2
|
ANTXR cell adhesion molecule 2
|
multiple interactions increases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of ANTXR2 mRNA Progesterone results in increased expression of ANTXR2 mRNA
|
CTD |
PMID:20660070 PMID:20864642 PMID:22238285 |
|
NCBI chr14:11,541,718...11,682,110
Ensembl chr14:11,845,700...11,986,168
|
|
| G
|
Anxa3
|
annexin A3
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of ANXA3 mRNA
|
CTD |
PMID:21540246 |
|
NCBI chr14:13,031,675...13,085,678
Ensembl chr14:13,023,762...13,085,849
|
|
| G
|
Aoc3
|
amine oxidase, copper containing 3
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of AOC3 mRNA
|
CTD |
PMID:19693291 |
|
NCBI chr10:86,773,018...86,780,961
|
|
| G
|
Aox1
|
aldehyde oxidase 1
|
increases expression
|
ISO EXP
|
Progesterone results in increased expression of AOX1 mRNA
|
CTD |
PMID:20726854 PMID:21540246 PMID:21795739 |
|
NCBI chr 9:67,073,831...67,152,980
Ensembl chr 9:67,073,821...67,152,980
|
|
| G
|
Ap3m2
|
adaptor related protein complex 3 subunit mu 2
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of AP3M2 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr16:69,217,526...69,237,372
Ensembl chr16:75,920,084...75,937,923
|
|
| G
|
Ap5m1
|
adaptor related protein complex 5 subunit mu 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of AP5M1 mRNA
|
CTD |
PMID:21453500 |
|
NCBI chr15:22,355,478...22,385,222
Ensembl chr15:24,835,100...24,862,606
|
|
| G
|
Apcdd1
|
APC down-regulated 1
|
increases expression
|
ISO
|
Progesterone results in increased expression of APCDD1 mRNA
|
CTD |
PMID:20864642 |
|
NCBI chr18:58,655,696...58,686,359
Ensembl chr18:58,655,919...58,686,356
|
|
| G
|
Apex1
|
apurinic/apyrimidinic endodeoxyribonuclease 1
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of APEX1 mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr15:24,144,595...24,146,785
Ensembl chr15:26,618,224...26,620,329
|
|
| G
|
Apoc4
|
apolipoprotein C4
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of APOC4 mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr 1:88,463,713...88,467,909
Ensembl chr 1:88,463,713...88,468,044
|
|
| G
|
Apod
|
apolipoprotein D
|
multiple interactions increases expression
|
ISO
|
[Progesterone co-treated with Estradiol] results in increased expression of APOD mRNA Progesterone results in increased expression of APOD mRNA
|
CTD |
PMID:17404688 PMID:20864642 PMID:21795739 |
|
NCBI chr11:82,936,216...82,957,264
Ensembl chr11:82,936,038...82,957,263
|
|
| G
|
Apom
|
apolipoprotein M
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in increased expression of APOM mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr20:3,695,618...3,698,218
Ensembl chr20:3,692,737...3,698,218
|
|
| G
|
App
|
amyloid beta precursor protein
|
decreases metabolic processing multiple interactions
|
ISO
|
APP gene mutant form results in decreased metabolism of Progesterone metabolite Progesterone inhibits the reaction [APP gene mutant form results in decreased metabolism of Progesterone metabolite]
|
CTD |
PMID:17988898 |
|
NCBI chr11:37,506,207...37,724,351
Ensembl chr11:37,506,408...37,722,971
|
|
| G
|
Aqp1
|
aquaporin 1
|
affects localization increases expression multiple interactions
|
EXP
|
Progesterone affects the localization of AQP1 protein Progesterone results in increased expression of AQP1 mRNA [Estradiol co-treated with Progesterone] results in decreased expression of AQP1 mRNA; [Estradiol co-treated with Progesterone] results in increased expression of AQP1 protein; [Progesterone co-treated with Estrogens] affects the localization of AQP1 protein; Quercetin inhibits the reaction [[Estradiol co-treated with Progesterone] results in decreased expression of AQP1 mRNA]; Quercetin promotes the reaction [[Estradiol co-treated with Progesterone] results in increased expression of AQP1 protein]
|
CTD |
PMID:16452730 PMID:20726854 PMID:28341573 |
|
NCBI chr 4:85,812,784...85,824,964
Ensembl chr 4:85,812,784...85,830,504
|
|
| G
|
Aqp2
|
aquaporin 2
|
increases expression multiple interactions
|
ISO EXP
|
Progesterone results in increased expression of AQP2 mRNA [Estradiol co-treated with Progesterone] results in decreased expression of AQP2 mRNA; [Estradiol co-treated with Progesterone] results in decreased expression of AQP2 protein; Quercetin inhibits the reaction [[Estradiol co-treated with Progesterone] results in decreased expression of AQP2 mRNA]; Quercetin inhibits the reaction [[Estradiol co-treated with Progesterone] results in decreased expression of AQP2 protein]
|
CTD |
PMID:18692832 PMID:28341573 |
|
NCBI chr 7:132,590,286...132,595,321
Ensembl chr 7:132,590,225...132,595,319
|
|
| G
|
Aqp3
|
aquaporin 3 (Gill blood group)
|
multiple interactions decreases expression
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of AQP3 mRNA Progesterone results in decreased expression of AQP3 mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr 5:61,035,165...61,040,683
Ensembl chr 5:61,035,166...61,040,685
|
|
| G
|
Aqp5
|
aquaporin 5
|
affects localization decreases expression multiple interactions
|
EXP ISO
|
Progesterone affects the localization of AQP5 protein Progesterone results in decreased expression of AQP5 mRNA [Estradiol co-treated with Progesterone] results in increased expression of AQP5 mRNA; [Estradiol co-treated with Progesterone] results in increased expression of AQP5 protein; [Progesterone co-treated with Estrogens] affects the localization of AQP5 protein; Progesterone inhibits the reaction [Estradiol results in decreased expression of AQP5 mRNA]; Progesterone promotes the reaction [Estradiol results in decreased expression of AQP5 protein]; Quercetin affects the reaction [[Estradiol co-treated with Progesterone] results in increased expression of AQP5 mRNA]
|
CTD |
PMID:16452730 PMID:22238285 PMID:28341573 |
|
NCBI chr 7:130,722,675...130,726,207
Ensembl chr 7:132,601,059...132,605,062
|
|
| G
|
Aqp7
|
aquaporin 7
|
multiple interactions
|
EXP
|
[Estradiol co-treated with Progesterone] results in increased expression of AQP7 mRNA; [Estradiol co-treated with Progesterone] results in increased expression of AQP7 protein; Quercetin inhibits the reaction [[Estradiol co-treated with Progesterone] results in increased expression of AQP7 mRNA]; Quercetin inhibits the reaction [[Estradiol co-treated with Progesterone] results in increased expression of AQP7 protein]
|
CTD |
PMID:28341573 |
|
NCBI chr 5:56,171,649...56,186,642
Ensembl chr 5:60,967,558...60,982,618
|
|
| G
|
Ar
|
androgen receptor
|
multiple interactions decreases expression affects activity increases activity affects binding
|
EXP ISO
|
Progesterone analog binds to and results in decreased activity of AR protein Progesterone results in decreased expression of AR mRNA Progesterone affects the activity of AR protein Progesterone results in increased activity of AR protein Progesterone binds to and results in decreased activity of AR protein; Progesterone binds to and results in increased activity of AR protein; Progesterone inhibits the reaction [Dihydrotestosterone results in increased activity of AR protein]; Progesterone inhibits the reaction [Metribolone results in increased activity of AR protein] Progesterone binds to AR protein
|
CTD |
PMID:9073609 PMID:12676605 PMID:14565775 PMID:15084347 PMID:17804755 PMID:18324785 PMID:19833195 PMID:20359488 PMID:20438827 PMID:21543282 PMID:26867867 PMID:28803809 PMID:33728745 More...
|
|
NCBI chr X:67,135,317...67,304,476
Ensembl chr X:67,135,317...67,304,467
|
|
| G
|
Araf
|
A-Raf proto-oncogene, serine/threonine kinase
|
affects expression
|
ISO
|
Progesterone affects the expression of ARAF mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr X:3,780,932...3,845,919
Ensembl chr X:3,780,932...3,792,611
|
|
| G
|
Arap3
|
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of ARAP3 mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr18:29,806,214...29,834,217
Ensembl chr18:30,058,275...30,084,865
|
|
| G
|
Arc
|
activity-regulated cytoskeleton-associated protein
|
decreases expression
|
EXP
|
Progesterone results in decreased expression of ARC mRNA
|
CTD |
PMID:16376865 |
|
NCBI chr 7:108,444,959...108,448,413
Ensembl chr 7:108,444,692...108,451,220
|
|
| G
|
Areg
|
amphiregulin
|
multiple interactions increases expression affects expression increases abundance
|
ISO EXP
|
[Progesterone affects the activity of PGR protein alternative form] which affects the expression of AREG mRNA Progesterone results in increased expression of AREG mRNA [Methylnitrosourea co-treated with Progesterone co-treated with Estradiol] results in increased expression of AREG mRNA; [Methylnitrosourea co-treated with Progesterone] results in increased expression of AREG mRNA; [Progesterone co-treated with Estrogens] results in increased expression of AREG protein; Estrogens promotes the reaction [Progesterone results in increased expression of AREG mRNA] Progesterone affects the expression of AREG [Estradiol co-treated with Progesterone co-treated with Corn Oil] results in increased expression of AREG mRNA; [Estradiol co-treated with Progesterone] results in increased expression of AREG mRNA; Estradiol promotes the reaction [Progesterone inhibits the reaction [perfluorooctanoic acid results in decreased expression of AREG protein]]; NRG1 protein promotes the reaction [AREG protein results in increased abundance of Progesterone]; Progesterone inhibits the reaction [perfluorooctanoic acid results in decreased expression of AREG protein]; Progesterone promotes the reaction [Estradiol inhibits the reaction [perfluorooctanoic acid results in decreased expression of AREG protein]]
|
CTD |
PMID:15178747 PMID:15866122 PMID:16794005 PMID:18070364 PMID:18556351 PMID:18591650 PMID:20732338 PMID:21047912 PMID:21258428 PMID:22414604 PMID:32186404 More...
|
|
NCBI chr14:17,256,384...17,265,641
Ensembl chr14:17,256,384...17,265,641
|
|
| G
|
Arfgap2
|
ARF GTPase activating protein 2
|
affects expression
|
ISO
|
Progesterone affects the expression of ARFGAP2 mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr 3:97,692,105...97,704,246
Ensembl chr 3:97,692,110...97,704,247
|
|
| G
|
Arg1
|
arginase 1
|
affects expression multiple interactions
|
ISO
|
Progesterone affects the expression of ARG1 mRNA Progesterone inhibits the reaction [[Lipopolysaccharides co-treated with IL4 protein] results in increased expression of ARG1 mRNA]; Progesterone inhibits the reaction [IL4 protein results in increased expression of ARG1 mRNA]; Progesterone inhibits the reaction [Lipopolysaccharides results in increased expression of ARG1 mRNA]
|
CTD |
PMID:17251523 PMID:21977998 |
|
NCBI chr 1:22,295,093...22,307,720
Ensembl chr 1:22,295,322...22,307,713
|
|
| G
|
Arg2
|
arginase 2
|
multiple interactions decreases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of ARG2 mRNA Progesterone results in decreased expression of ARG2 mRNA
|
CTD |
PMID:20660070 PMID:22238285 |
|
NCBI chr 6:103,669,001...103,694,375
Ensembl chr 6:103,668,988...103,694,375
|
|
| G
|
Arhgap18
|
Rho GTPase activating protein 18
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of ARHGAP18 mRNA
|
CTD |
PMID:20864642 |
|
NCBI chr 1:20,222,948...20,456,827
Ensembl chr 1:20,222,954...20,456,670
|
|
| G
|
Arhgap28
|
Rho GTPase activating protein 28
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of ARHGAP28 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 9:115,277,849...115,444,789
Ensembl chr 9:115,279,734...115,445,008
|
|
| G
|
Arhgdia
|
Rho GDP dissociation inhibitor alpha
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of ARHGDIA mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr10:105,854,526...105,858,020
Ensembl chr10:106,353,491...106,356,347
|
|
| G
|
Arhgef17
|
Rho guanine nucleotide exchange factor 17
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of ARHGEF17 mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr 1:164,642,690...164,702,241
Ensembl chr 1:164,642,690...164,702,241
|
|
| G
|
Arhgef3
|
Rho guanine nucleotide exchange factor 3
|
increases expression
|
ISO
|
Progesterone results in increased expression of ARHGEF3 mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr16:2,308,311...2,588,634
Ensembl chr16:2,308,400...2,588,819
|
|
| G
|
Arl4a
|
ARF like GTPase 4A
|
increases expression
|
ISO
|
Progesterone results in increased expression of ARL4A mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr 6:62,809,287...62,811,297
Ensembl chr 6:62,804,548...62,820,760
|
|
| G
|
Arl4c
|
ARF like GTPase 4C
|
affects expression multiple interactions decreases expression
|
ISO
|
Progesterone affects the expression of ARL4C mRNA [Estradiol co-treated with Progesterone] results in decreased expression of ARL4C mRNA Progesterone results in decreased expression of ARL4C mRNA
|
CTD |
PMID:17251523 PMID:20660070 PMID:20864642 |
|
NCBI chr 9:96,748,075...96,751,510
Ensembl chr 9:96,745,069...96,752,772
|
|
| G
|
Armc9
|
armadillo repeat containing 9
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of ARMC9 mRNA
|
CTD |
PMID:21795739 |
|
NCBI chr 9:86,802,791...86,928,611
Ensembl chr 9:94,250,859...94,376,589
|
|
| G
|
Arnt
|
aryl hydrocarbon receptor nuclear translocator
|
affects expression multiple interactions
|
EXP
|
Progesterone affects the expression of ARNT mRNA [Progesterone co-treated with Estradiol] affects the expression of ARNT mRNA
|
CTD |
PMID:24777823 |
|
NCBI chr 2:182,997,731...183,056,584
Ensembl chr 2:185,680,683...185,745,546
|
|
| G
|
Arnt2
|
aryl hydrocarbon receptor nuclear translocator 2
|
affects expression
|
EXP
|
Progesterone affects the expression of ARNT2 mRNA
|
CTD |
PMID:24777823 |
|
NCBI chr 1:138,236,235...138,392,868
Ensembl chr 1:147,599,058...147,801,997
|
|
| G
|
Arpc4
|
actin related protein 2/3 complex, subunit 4
|
affects expression
|
ISO
|
Progesterone affects the expression of ARPC4 mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr 4:146,522,255...146,532,784
Ensembl chr 4:148,077,240...148,088,428
|
|
| G
|
Arpin
|
actin-related protein 2/3 complex inhibitor
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of ARPIN mRNA
|
CTD |
PMID:21453500 |
|
NCBI chr 1:133,864,288...133,873,124
Ensembl chr 1:143,273,590...143,282,532
|
|
| G
|
Art3
|
ADP-ribosyltransferase 3
|
multiple interactions increases expression
|
ISO EXP
|
[Estradiol co-treated with Progesterone] results in increased expression of ART3 mRNA; [Progesterone co-treated with Estradiol] results in increased expression of ART3 mRNA Progesterone results in increased expression of ART3 mRNA
|
CTD |
PMID:17404688 PMID:20660070 PMID:20726854 |
|
NCBI chr14:15,921,540...16,003,764
Ensembl chr14:15,921,395...15,949,806
|
|
| G
|
Asap2
|
ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
|
multiple interactions increases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of ASAP2 mRNA Progesterone results in increased expression of ASAP2 mRNA
|
CTD |
PMID:18037150 PMID:20660070 |
|
NCBI chr 6:40,658,201...40,821,017
Ensembl chr 6:46,386,605...46,549,669
|
|
| G
|
Asb2
|
ankyrin repeat and SOCS box-containing 2
|
multiple interactions increases expression
|
ISO
|
[Progesterone co-treated with TGFB1 protein] results in increased expression of ASB2 mRNA Progesterone results in increased expression of ASB2 mRNA
|
CTD |
PMID:21768398 |
|
NCBI chr 6:128,239,550...128,275,833
Ensembl chr 6:128,239,552...128,266,321
|
|
| G
|
Asgr1
|
asialoglycoprotein receptor 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of ASGR1 mRNA
|
CTD |
PMID:19693291 |
|
NCBI chr10:55,274,299...55,278,323
Ensembl chr10:55,274,706...55,278,322
|
|
| G
|
Asns
|
asparagine synthetase (glutamine-hydrolyzing)
|
increases expression
|
ISO
|
Progesterone results in increased expression of ASNS mRNA
|
CTD |
PMID:18037150 PMID:21795739 |
|
NCBI chr 4:36,752,061...36,769,970
Ensembl chr 4:36,751,802...36,776,050
|
|
| G
|
Asph
|
aspartate-beta-hydroxylase
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of ASPH mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 5:22,601,581...22,814,107
Ensembl chr 5:27,398,949...27,611,215
|
|
| G
|
Asphd2
|
aspartate beta-hydroxylase domain containing 2
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of ASPHD2 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr12:49,908,539...49,919,060
Ensembl chr12:49,908,241...49,925,254
|
|
| G
|
Aspm
|
assembly factor for spindle microtubules
|
increases expression
|
ISO
|
Progesterone results in increased expression of ASPM mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr13:53,625,584...53,674,489
Ensembl chr13:53,625,584...53,674,489
|
|
| G
|
Aspn
|
asporin
|
multiple interactions increases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of ASPN mRNA Progesterone results in increased expression of ASPN mRNA
|
CTD |
PMID:20660070 PMID:21795739 |
|
NCBI chr17:15,286,338...15,310,567
Ensembl chr17:15,287,065...15,310,632
|
|
| G
|
Asrgl1
|
asparaginase and isoaspartyl peptidase 1
|
multiple interactions decreases expression
|
ISO
|
[Progesterone co-treated with Estradiol] results in increased expression of ASRGL1 mRNA Progesterone results in decreased expression of ASRGL1 mRNA
|
CTD |
PMID:17404688 PMID:21540246 |
|
NCBI chr 1:215,436,180...215,456,188
Ensembl chr 1:215,435,218...215,456,198
|
|
| G
|
Atad2
|
ATPase family, AAA domain containing 2
|
multiple interactions increases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of ATAD2 mRNA; [Progesterone co-treated with Estradiol] results in increased expression of ATAD2 mRNA Progesterone results in increased expression of ATAD2 mRNA
|
CTD |
PMID:17404688 PMID:20660070 |
|
NCBI chr 7:91,523,626...91,566,238
Ensembl chr 7:91,523,626...91,566,238
|
|
| G
|
Atf3
|
activating transcription factor 3
|
multiple interactions increases expression
|
ISO
|
Mifepristone inhibits the reaction [Progesterone results in increased expression of ATF3 mRNA]
|
CTD |
PMID:15674352 |
|
NCBI chr13:105,274,103...105,331,653
Ensembl chr13:105,282,440...105,295,750
|
|
| G
|
Atf4
|
activating transcription factor 4
|
increases expression
|
ISO
|
Progesterone results in increased expression of ATF4 mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr 7:113,684,681...113,686,739
Ensembl chr 7:113,684,681...113,686,739
|
|
| G
|
Atg13
|
autophagy related 13
|
affects expression
|
ISO
|
Progesterone affects the expression of ATG13 mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr 3:98,102,831...98,136,741
Ensembl chr 3:98,101,552...98,136,743
|
|
| G
|
Atg2b
|
autophagy related 2B
|
increases expression
|
ISO
|
Progesterone results in increased expression of ATG2B mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr 6:124,522,283...124,592,412
Ensembl chr 6:130,286,986...130,357,109
|
|
| G
|
Atp10a
|
ATPase phospholipid transporting 10A (putative)
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of ATP10A mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 1:109,556,760...109,730,440
Ensembl chr 1:118,692,478...118,866,114
|
|
| G
|
Atp10b
|
ATPase phospholipid transporting 10B
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of ATP10B mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr10:27,996,729...28,252,801
Ensembl chr10:27,910,295...28,251,450
|
|
| G
|
Atp1a1
|
ATPase Na+/K+ transporting subunit alpha 1
|
increases expression increases activity
|
ISO EXP
|
Progesterone results in increased expression of ATP1A1 mRNA Progesterone results in increased activity of ATP1A1 protein
|
CTD |
PMID:18037150 PMID:20726854 PMID:22759964 |
|
NCBI chr 2:191,709,311...191,737,414
Ensembl chr 2:191,709,311...191,737,425
|
|
| G
|
Atp1b1
|
ATPase Na+/K+ transporting subunit beta 1
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of ATP1B1 mRNA
|
CTD |
PMID:21540246 |
|
NCBI chr13:79,319,708...79,340,226
Ensembl chr13:79,319,706...79,340,549
|
|
| G
|
Atp2a1
|
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
|
multiple interactions decreases expression
|
ISO
|
Mifepristone inhibits the reaction [Progesterone results in decreased expression of ATP2A1 mRNA]
|
CTD |
PMID:27264040 |
|
NCBI chr 1:190,457,198...190,475,410
Ensembl chr 1:190,457,198...190,475,423
|
|
| G
|
Atp2a2
|
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2
|
increases expression
|
EXP
|
Progesterone results in increased expression of ATP2A2 mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr12:39,733,519...39,782,942
Ensembl chr12:39,733,458...39,782,934
|
|
| G
|
Atp2b4
|
ATPase plasma membrane Ca2+ transporting 4
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of ATP2B4 mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr13:45,156,137...45,255,292
Ensembl chr13:47,711,121...47,758,876
|
|
| G
|
Atp2c2
|
ATPase secretory pathway Ca2+ transporting 2
|
multiple interactions increases expression
|
ISO
|
NCOA2 protein affects the reaction [Progesterone results in increased expression of ATP2C2 mRNA]
|
CTD |
PMID:17556502 |
|
NCBI chr19:64,662,729...64,719,998
Ensembl chr19:64,662,715...64,719,996
|
|
| G
|
Atp5f1b
|
ATP synthase F1 subunit beta
|
increases phosphorylation
|
EXP
|
Progesterone results in increased phosphorylation of ATP5F1B protein
|
CTD |
PMID:17303654 |
|
NCBI chr 7:1,100,058...1,106,461
Ensembl chr 7:1,099,860...1,106,462
|
|
| G
|
Atp6v1a
|
ATPase H+ transporting V1 subunit A
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in increased expression of ATP6V1A mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr11:70,066,800...70,120,603
Ensembl chr11:70,035,134...70,120,603
|
|
| G
|
Atp7b
|
ATPase copper transporting beta
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of ATP7B mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr16:76,654,725...76,726,092
Ensembl chr16:76,653,660...76,728,801
|
|
| G
|
Atp8a1
|
ATPase phospholipid transporting 8A1
|
affects expression
|
ISO
|
Progesterone affects the expression of ATP8A1 mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr14:40,668,932...40,911,465
Ensembl chr14:40,731,846...40,911,463
|
|
| G
|
Atp8a2
|
ATPase phospholipid transporting 8A2
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of ATP8A2 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr15:37,993,507...38,526,408
Ensembl chr15:38,002,305...38,526,212
|
|
| G
|
Atp8b1
|
ATPase phospholipid transporting 8B1
|
multiple interactions decreases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of ATP8B1 mRNA Progesterone results in decreased expression of ATP8B1 mRNA
|
CTD |
PMID:20660070 PMID:20864642 |
|
NCBI chr18:60,286,605...60,427,862
Ensembl chr18:60,288,464...60,427,027
|
|
| G
|
Aurka
|
aurora kinase A
|
increases expression decreases expression multiple interactions
|
ISO EXP
|
Progesterone results in increased expression of AURKA mRNA Progesterone results in decreased expression of AURKA mRNA [Estrogens co-treated with Progesterone] inhibits the reaction [Methylnitrosourea results in increased expression of AURKA mRNA]
|
CTD |
PMID:12124350 PMID:16888808 PMID:21795739 |
|
NCBI chr 3:181,546,742...181,562,890
Ensembl chr 3:181,546,742...181,562,771
|
|
| G
|
Aurkb
|
aurora kinase B
|
decreases expression
|
EXP
|
Progesterone results in decreased expression of AURKB mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr10:54,243,116...54,249,675
Ensembl chr10:54,242,850...54,252,285
|
|
| G
|
Avp
|
arginine vasopressin
|
decreases expression
|
EXP
|
Progesterone results in decreased expression of AVP protein
|
CTD |
PMID:16454802 |
|
NCBI chr 3:138,246,544...138,248,522
Ensembl chr 3:138,246,554...138,248,522
|
|
| G
|
Avpi1
|
arginine vasopressin-induced 1
|
multiple interactions increases expression
|
ISO EXP
|
[Estradiol co-treated with Progesterone] results in increased expression of AVPI1 mRNA Progesterone results in increased expression of AVPI1 mRNA
|
CTD |
PMID:20660070 PMID:20726854 |
|
NCBI chr 1:250,879,530...250,885,448
Ensembl chr 1:250,879,530...250,885,704
|
|
| G
|
Avpr1a
|
arginine vasopressin receptor 1A
|
increases expression
|
ISO
|
Progesterone results in increased expression of AVPR1A mRNA
|
CTD |
PMID:20864642 PMID:22238285 |
|
NCBI chr 7:59,999,743...60,003,667
Ensembl chr 7:59,999,738...60,003,837
|
|
| G
|
Axin1
|
axin 1
|
affects expression increases expression
|
ISO EXP
|
Progesterone affects the expression of AXIN1 mRNA Progesterone results in increased expression of AXIN1 mRNA
|
CTD |
PMID:17170212 PMID:17251523 |
|
NCBI chr10:15,667,894...15,720,092
Ensembl chr10:15,667,958...15,720,092
|
|
| G
|
Axin2
|
axin 2
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of AXIN2 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr10:94,393,379...94,426,579
Ensembl chr10:94,395,909...94,426,575
|
|
| G
|
B3gnt5
|
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
|
increases expression
|
ISO
|
Progesterone results in increased expression of B3GNT5 mRNA
|
CTD |
PMID:21795739 |
|
NCBI chr11:94,645,480...94,657,584
Ensembl chr11:94,645,480...94,660,514
|
|
| G
|
B4galt2
|
beta-1,4-galactosyltransferase 2
|
decreases expression affects expression
|
ISO
|
Progesterone results in decreased expression of B4GALT2 mRNA Progesterone affects the expression of B4GALT2 mRNA
|
CTD |
PMID:17251523 PMID:18037150 |
|
NCBI chr 5:131,412,541...131,422,573
Ensembl chr 5:136,697,981...136,710,422
|
|
| G
|
B4galt6
|
beta-1,4-galactosyltransferase 6
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of B4GALT6 mRNA
|
CTD |
PMID:19693291 |
|
NCBI chr18:12,233,350...12,290,204
Ensembl chr18:12,233,351...12,290,204
|
|
| G
|
Baalc
|
BAALC binder of MAP3K1 and KLF4
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of BAALC mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 7:69,918,998...69,992,289
Ensembl chr 7:71,774,898...71,879,261
|
|
| G
|
Bach1
|
BTB domain and CNC homolog 1
|
affects expression
|
ISO
|
Progesterone affects the expression of BACH1 mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr11:40,425,721...40,461,118
Ensembl chr11:40,425,664...40,461,277
|
|
| G
|
Bad
|
BCL2-associated agonist of cell death
|
decreases expression multiple interactions
|
EXP
|
Progesterone results in decreased expression of BAD mRNA [Methylnitrosourea co-treated with Progesterone co-treated with Estradiol] results in decreased expression of BAD mRNA
|
CTD |
PMID:15941375 PMID:20732338 |
|
NCBI chr 1:213,562,719...213,572,034
Ensembl chr 1:213,562,187...213,572,034
|
|
| G
|
Bag1
|
BAG cochaperone 1
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of BAG1 mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr 5:60,864,476...60,877,059
Ensembl chr 5:60,864,476...60,878,161
|
|
| G
|
Bag3
|
BAG cochaperone 3
|
increases expression
|
ISO
|
Progesterone results in increased expression of BAG3 mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr 1:183,103,038...183,126,862
Ensembl chr 1:192,475,828...192,557,280
|
|
| G
|
Bag4
|
BAG cochaperone 4
|
decreases expression
|
EXP
|
Progesterone results in decreased expression of BAG4 mRNA
|
CTD |
PMID:21770760 |
|
NCBI chr16:66,288,678...66,305,893
Ensembl chr16:72,991,362...73,013,273
|
|
| G
|
Bag5
|
BAG cochaperone 5
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of BAG5 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 6:136,589,623...136,593,278
Ensembl chr 6:136,584,741...136,598,492
|
|
| G
|
Baiap2
|
BAR/IMD domain containing adaptor protein 2
|
multiple interactions increases expression
|
ISO EXP
|
[Estradiol co-treated with Progesterone] results in increased expression of BAIAP2 mRNA Progesterone results in increased expression of BAIAP2 mRNA
|
CTD |
PMID:20660070 PMID:20726854 |
|
NCBI chr10:105,721,371...105,788,549
Ensembl chr10:105,721,417...105,788,549
|
|
| G
|
Batf3
|
basic leucine zipper ATF-like transcription factor 3
|
increases expression
|
ISO
|
Progesterone results in increased expression of BATF3 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr13:105,220,782...105,232,365
Ensembl chr13:105,220,390...105,232,369
|
|
| G
|
Bax
|
BCL2 associated X, apoptosis regulator
|
decreases expression increases expression multiple interactions
|
EXP ISO
|
Progesterone results in decreased expression of BAX mRNA Progesterone results in increased expression of BAX protein CALB1 protein inhibits the reaction [Progesterone results in increased expression of BAX protein]; S100G protein inhibits the reaction [Progesterone results in increased expression of BAX protein] [Estradiol co-treated with Progesterone co-treated with Methylnitrosourea] results in decreased expression of BAX protein; [Methylnitrosourea co-treated with Progesterone co-treated with Estradiol] results in decreased expression of BAX mRNA; [Methylnitrosourea co-treated with Progesterone] results in decreased expression of BAX mRNA
|
CTD |
PMID:15941375 PMID:20732338 PMID:21882229 PMID:22465879 |
|
NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429
|
|
| G
|
Baz1a
|
bromodomain adjacent to zinc finger domain, 1A
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of BAZ1A mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 6:72,389,701...72,512,516
Ensembl chr 6:78,124,872...78,247,648
|
|
| G
|
Bbs10
|
Bardet-Biedl syndrome 10
|
increases expression
|
ISO
|
Progesterone results in increased expression of BBS10 mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr 7:48,637,324...48,640,395
Ensembl chr 7:48,637,356...48,640,391
|
|
| G
|
Bbs7
|
Bardet-Biedl syndrome 7
|
increases expression
|
ISO
|
Progesterone results in increased expression of BBS7 mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr 2:121,362,884...121,402,473
Ensembl chr 2:121,362,885...121,402,473
|
|
| G
|
Bcar3
|
BCAR3 adaptor protein, NSP family member
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of BCAR3 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 2:213,209,907...213,323,305
Ensembl chr 2:213,209,893...213,323,302
|
|
| G
|
Bcat1
|
branched chain amino acid transaminase 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of BCAT1 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 4:179,695,662...179,777,973
Ensembl chr 4:179,695,662...179,777,288
|
|
| G
|
Bcat2
|
branched chain amino acid transaminase 2
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of BCAT2 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 1:105,175,157...105,196,474
Ensembl chr 1:105,176,977...105,196,463
|
|
| G
|
Bcl11a
|
BCL11 transcription factor A
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of BCL11A mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr14:102,230,147...102,325,289
Ensembl chr14:102,231,113...102,325,623
|
|
| G
|
Bcl2
|
BCL2, apoptosis regulator
|
increases expression multiple interactions
|
EXP ISO
|
Progesterone results in increased expression of BCL2 mRNA; Progesterone results in increased expression of BCL2 protein [Estradiol co-treated with Progesterone co-treated with Methylnitrosourea] results in increased expression of BCL2 protein; [Methylnitrosourea co-treated with Progesterone co-treated with Estradiol] results in increased expression of BCL2 mRNA; [Methylnitrosourea co-treated with Progesterone] results in increased expression of BCL2 mRNA; [Progesterone co-treated with Estradiol] results in decreased expression of BCL2 mRNA [Progesterone co-treated with Estrogens, Conjugated (USP)] results in increased expression of BCL2 protein
|
CTD |
PMID:15779298 PMID:15941375 PMID:18829022 PMID:20732338 PMID:22465879 |
|
NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900
|
|
| G
|
Bcl2l1
|
Bcl2-like 1
|
multiple interactions increases expression affects response to substance
|
EXP
|
BCL2L1 mRNA affects the reaction [Progesterone inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]]; Mifepristone inhibits the reaction [Progesterone results in increased expression of BCL2L1 protein] Progesterone results in increased expression of BCL2L1 mRNA; Progesterone results in increased expression of BCL2L1 protein BCL2L1 mRNA affects the susceptibility to Progesterone
|
CTD |
PMID:15941375 PMID:20726854 PMID:26915917 |
|
NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:161,745,540...161,764,907 Ensembl chr 1:161,745,540...161,764,907
|
|
| G
|
Bcl3
|
BCL3, transcription coactivator
|
affects expression
|
ISO
|
Progesterone affects the expression of BCL3 mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr 1:88,599,321...88,613,555
Ensembl chr 1:88,599,321...88,614,368
|
|
| G
|
Bcl6
|
BCL6, transcription repressor
|
increases expression
|
ISO
|
Progesterone results in increased expression of BCL6 mRNA
|
CTD |
PMID:33728745 |
|
NCBI chr11:90,358,753...90,382,049
Ensembl chr11:90,358,753...90,382,047
|
|
| G
|
Bdh1
|
3-hydroxybutyrate dehydrogenase 1
|
increases expression
|
ISO
|
Progesterone results in increased expression of BDH1 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr11:82,806,125...82,848,133
Ensembl chr11:82,807,503...82,842,636
|
|
| G
|
Bdh2
|
3-hydroxybutyrate dehydrogenase 2
|
increases expression
|
ISO
|
Progesterone results in increased expression of BDH2 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 2:226,376,346...226,397,010
Ensembl chr 2:226,376,356...226,397,006
|
|
| G
|
Bdkrb1
|
bradykinin receptor B1
|
multiple interactions decreases expression
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of BDKRB1 mRNA Progesterone results in decreased expression of BDKRB1 mRNA
|
CTD |
PMID:17404688 PMID:20864642 PMID:21795739 |
|
NCBI chr 6:130,275,631...130,284,968
Ensembl chr 6:130,275,478...130,280,973
|
|
| G
|
Bdnf
|
brain-derived neurotrophic factor
|
decreases expression increases expression multiple interactions affects localization
|
ISO EXP
|
Progesterone results in decreased expression of BDNF mRNA Progesterone results in increased expression of BDNF mRNA; Progesterone results in increased expression of BDNF protein Progesterone inhibits the reaction [Estradiol results in increased expression of BDNF protein] Progesterone inhibits the reaction [VPS54 gene mutant form results in decreased expression of BDNF mRNA] Progesterone affects the localization of BDNF protein
|
CTD |
PMID:15570173 PMID:17052708 PMID:17549730 PMID:18070364 PMID:23157231 |
|
NCBI chr 3:116,619,633...116,670,212
Ensembl chr 3:116,619,633...116,670,657
|
|
| G
|
Bend6
|
BEN domain containing 6
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of BEND6 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 9:36,081,033...36,135,309
Ensembl chr 9:43,576,982...43,631,194
|
|
| G
|
Bet1
|
Bet1 golgi vesicular membrane trafficking protein
|
increases expression
|
ISO
|
Progesterone results in increased expression of BET1 mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr 4:33,070,892...33,081,162
Ensembl chr 4:33,070,891...33,081,164
|
|
| G
|
Bhlhe40
|
basic helix-loop-helix family, member e40
|
increases expression
|
ISO
|
Progesterone results in increased expression of BHLHE40 mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr 4:143,174,450...143,180,150
Ensembl chr 4:143,174,048...143,180,783
|
|
| G
|
Bhlhe41
|
basic helix-loop-helix family, member e41
|
multiple interactions decreases expression
|
ISO EXP
|
[Estradiol co-treated with Progesterone] results in decreased expression of BHLHE41 mRNA; [Progesterone co-treated with Estradiol] results in decreased expression of BHLHE41 mRNA Progesterone results in decreased expression of BHLHE41 mRNA
|
CTD |
PMID:17404688 PMID:20660070 PMID:20726854 |
|
NCBI chr 4:180,565,003...180,569,415
Ensembl chr 4:180,565,003...180,569,355
|
|
| G
|
Bicd1
|
BICD cargo adaptor 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of BICD1 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 4:182,479,071...182,631,504
Ensembl chr 4:184,210,363...184,357,391
|
|
| G
|
Bid
|
BH3 interacting domain death agonist
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of BID mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr 4:155,785,366...155,808,775
Ensembl chr 4:155,785,377...155,808,275
|
|
| G
|
Bin1
|
bridging integrator 1
|
increases expression
|
ISO
|
Progesterone results in increased expression of BIN1 mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr18:24,282,840...24,341,461
Ensembl chr18:24,283,801...24,341,458
|
|
| G
|
Birc2
|
baculoviral IAP repeat-containing 2
|
increases expression
|
EXP
|
Progesterone results in increased expression of BIRC2 mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr 8:13,253,697...13,273,672
Ensembl chr 8:13,253,706...13,271,911
|
|
| G
|
Birc3
|
baculoviral IAP repeat-containing 3
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of BIRC3 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 8:13,285,702...13,313,329
Ensembl chr 8:13,285,703...13,298,590
|
|
| G
|
Birc5
|
baculoviral IAP repeat-containing 5
|
decreases expression increases expression
|
ISO
|
Progesterone results in decreased expression of BIRC5 mRNA Progesterone results in increased expression of BIRC5 mRNA
|
CTD |
PMID:21549006 PMID:21795739 |
|
NCBI chr10:103,567,369...103,580,069
Ensembl chr10:103,572,080...103,582,155
|
|
| G
|
Blm
|
BLM RecQ like helicase
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of BLM mRNA
|
CTD |
PMID:21453500 |
|
NCBI chr 1:134,409,832...134,496,073
Ensembl chr 1:143,819,090...143,905,210
|
|
| G
|
Blnk
|
B-cell linker
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of BLNK mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 1:249,703,064...249,770,533
Ensembl chr 1:249,703,072...249,770,533
|
|
| G
|
Bmal1
|
basic helix-loop-helix ARNT like 1
|
increases expression
|
ISO
|
Progesterone results in increased expression of BMAL1 mRNA
|
CTD |
PMID:20096720 |
|
NCBI chr 1:176,766,222...176,864,741
Ensembl chr 1:176,829,305...176,864,739
|
|
| G
|
Bmerb1
|
bMERB domain containing 1
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of BMERB1 mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr10:1,779,834...1,946,586
Ensembl chr10:2,287,000...2,453,728
|
|
| G
|
Bmf
|
Bcl2 modifying factor
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of BMF mRNA
|
CTD |
PMID:18556351 |
|
NCBI chr 3:125,953,466...125,974,087
Ensembl chr 3:125,953,466...125,974,258
|
|
| G
|
Bmp15
|
bone morphogenetic protein 15
|
multiple interactions
|
EXP
|
[BMP15 protein results in decreased expression of STAR mRNA] inhibits the reaction [FSHB protein results in increased abundance of Progesterone]; IGF1 protein inhibits the reaction [BMP15 protein inhibits the reaction [FSHB protein results in increased abundance of Progesterone]]
|
CTD |
PMID:22067323 |
|
NCBI chr X:16,169,123...16,174,187
Ensembl chr X:18,840,829...18,847,438
|
|
| G
|
Bmp2
|
bone morphogenetic protein 2
|
multiple interactions decreases expression decreases abundance
|
ISO EXP
|
[Estradiol co-treated with Progesterone co-treated with Corn Oil] results in increased expression of BMP2 mRNA; NCOA2 protein affects the reaction [Progesterone results in decreased expression of BMP2 mRNA]; PGR protein affects the reaction [Progesterone results in decreased expression of BMP2 mRNA] [BMP2 protein results in decreased expression of STAR mRNA] inhibits the reaction [FSHB protein results in increased abundance of Progesterone]; IGF1 protein inhibits the reaction [BMP2 protein inhibits the reaction [FSHB protein results in increased abundance of Progesterone]] BMP2 protein results in decreased abundance of Progesterone 4-(2-aminoethyl)benzenesulfonylfluoride inhibits the reaction [[Estradiol co-treated with Progesterone] results in decreased expression of BMP2 mRNA]; [Estradiol co-treated with Progesterone] results in decreased expression of BMP2 mRNA; N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide inhibits the reaction [[Estradiol co-treated with Progesterone] results in decreased expression of BMP2 mRNA]; NOG protein inhibits the reaction [BMP2 protein results in decreased abundance of Progesterone]
|
CTD |
PMID:17556502 PMID:20639315 PMID:20660070 PMID:22067323 PMID:23313114 PMID:32186404 More...
|
|
NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:141,264,646...141,274,760
|
|
| G
|
Bmp4
|
bone morphogenetic protein 4
|
multiple interactions
|
EXP
|
[BMP4 protein results in decreased expression of STAR mRNA] inhibits the reaction [FSHB protein results in increased abundance of Progesterone]; GH1 protein inhibits the reaction [BMP4 protein inhibits the reaction [FSHB protein results in increased abundance of Progesterone]]; IGF1 protein inhibits the reaction [BMP4 protein inhibits the reaction [FSHB protein results in increased abundance of Progesterone]]
|
CTD |
PMID:22067323 |
|
NCBI chr15:22,098,191...22,113,145
Ensembl chr15:22,098,470...22,105,172
|
|
| G
|
Bmp5
|
bone morphogenetic protein 5
|
multiple interactions decreases expression
|
ISO
|
NCOA2 protein affects the reaction [Progesterone results in decreased expression of BMP5 mRNA]; PGR protein affects the reaction [Progesterone results in decreased expression of BMP5 mRNA]
|
CTD |
PMID:17556502 |
|
NCBI chr 8:85,397,629...85,520,374
Ensembl chr 8:85,396,925...85,520,189
|
|
| G
|
Bmp6
|
bone morphogenetic protein 6
|
multiple interactions increases expression
|
ISO EXP
|
[Estradiol co-treated with Progesterone] results in decreased expression of BMP6 mRNA; BMP6 protein inhibits the reaction [Colforsin results in increased secretion of Progesterone]; FST protein inhibits the reaction [BMP6 protein inhibits the reaction [Colforsin results in increased secretion of Progesterone]] [BMP6 protein results in decreased expression of STAR mRNA] inhibits the reaction [FSHB protein results in increased abundance of Progesterone]; GH1 protein inhibits the reaction [BMP6 protein inhibits the reaction [FSHB protein results in increased abundance of Progesterone]]; IGF1 protein inhibits the reaction [BMP6 protein inhibits the reaction [FSHB protein results in increased abundance of Progesterone]] Progesterone results in increased expression of BMP6 mRNA
|
CTD |
PMID:18936084 PMID:20660070 PMID:20726854 PMID:22067323 |
|
NCBI chr17:26,523,704...26,785,558
Ensembl chr17:26,523,704...26,675,261
|
|
| G
|
Bmp7
|
bone morphogenetic protein 7
|
multiple interactions decreases expression increases expression
|
ISO EXP
|
[Estradiol co-treated with Progesterone] results in decreased expression of BMP7 mRNA; BMP7 protein inhibits the reaction [[Estradiol co-treated with Progesterone] results in increased expression of IGFBP1 mRNA]; BMP7 protein inhibits the reaction [[Estradiol co-treated with Progesterone] results in increased secretion of IGFBP1 protein] [BMP7 protein results in decreased expression of STAR mRNA] inhibits the reaction [FSHB protein results in increased abundance of Progesterone]; GH1 protein inhibits the reaction [BMP7 protein inhibits the reaction [FSHB protein results in increased abundance of Progesterone]]; IGF1 protein inhibits the reaction [BMP7 protein inhibits the reaction [FSHB protein results in increased abundance of Progesterone]] Progesterone results in decreased expression of BMP7 mRNA Progesterone results in increased expression of BMP7 mRNA
|
CTD |
PMID:20085912 PMID:20726854 PMID:22067323 |
|
NCBI chr 3:161,639,915...161,716,938
Ensembl chr 3:182,052,337...182,135,137
|
|
| G
|
Bnipl
|
BCL2 interacting protein like
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of BNIPL mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 2:185,507,591...185,519,415
Ensembl chr 2:185,507,593...185,517,582
|
|
| G
|
Bpgm
|
bisphosphoglycerate mutase
|
affects expression multiple interactions
|
ISO
|
Progesterone affects the expression of BPGM mRNA [Estradiol co-treated with Progesterone] results in decreased expression of BPGM mRNA
|
CTD |
PMID:17251523 PMID:20660070 |
|
NCBI chr 4:63,139,730...63,168,581
Ensembl chr 4:64,106,804...64,135,627
|
|
| G
|
Brd7
|
bromodomain containing 7
|
affects expression
|
ISO
|
Progesterone affects the expression of BRD7 mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr19:18,708,792...18,737,497
Ensembl chr19:34,882,304...34,910,944
|
|
| G
|
Brix1
|
biogenesis of ribosomes BRX1
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of BRIX1 mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr 2:61,177,769...61,188,647
Ensembl chr 2:61,177,771...61,188,647
|
|
| G
|
Btbd3
|
BTB domain containing 3
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of BTBD3 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 3:125,591,427...125,621,660
Ensembl chr 3:146,044,096...146,074,635
|
|
| G
|
Btd
|
biotinidase
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of BTD mRNA
|
CTD |
PMID:19693291 |
|
NCBI chr16:6,863,068...6,894,345
Ensembl chr16:6,869,291...6,901,410
|
|
| G
|
Btg2
|
BTG anti-proliferation factor 2
|
increases expression
|
EXP
|
Progesterone results in increased expression of BTG2 mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr13:48,083,931...48,087,690
Ensembl chr13:48,083,931...48,087,690
|
|
| G
|
Btnl9
|
butyrophilin-like 9
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of BTNL9 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr10:33,466,059...33,489,229
Ensembl chr10:33,970,675...33,990,354
|
|
| G
|
Btrc
|
beta-transducin repeat containing E3 ubiquitin protein ligase
|
increases expression
|
EXP
|
Progesterone results in increased expression of BTRC mRNA
|
CTD |
PMID:17170212 |
|
NCBI chr 1:254,159,085...254,324,819
Ensembl chr 1:254,159,124...254,328,357
|
|
| G
|
Bub1b
|
BUB1 mitotic checkpoint serine/threonine kinase B
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of BUB1B mRNA
|
CTD |
PMID:21795739 |
|
NCBI chr 3:126,017,019...126,069,470
Ensembl chr 3:126,017,045...126,069,796
|
|
| G
|
Bzw2
|
basic leucine zipper and W2 domains 2
|
affects expression
|
ISO
|
Progesterone affects the expression of BZW2 mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr 6:58,555,362...58,615,921
Ensembl chr 6:58,554,961...58,615,912
|
|
| G
|
C1qbp
|
complement C1q binding protein
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of C1QBP mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr10:56,198,534...56,203,185
Ensembl chr10:56,198,540...56,203,235
|
|
| G
|
C1qtnf7
|
C1q and TNF related 7
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of C1QTNF7 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr14:67,467,888...67,580,477
Ensembl chr14:71,680,479...71,792,865
|
|
| G
|
C2
|
complement C2
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of C2 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr20:3,944,722...3,975,006
Ensembl chr20:3,955,776...3,981,740
|
|
| G
|
C2cd4a
|
C2 calcium-dependent domain containing 4A
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of C2CD4A mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 8:68,467,017...68,469,781
Ensembl chr 8:77,348,310...77,359,958
|
|
| G
|
C2cd4b
|
C2 calcium-dependent domain containing 4B
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of C2CD4B mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 8:77,254,327...77,277,620
Ensembl chr 8:77,238,551...77,279,879
|
|
| G
|
C3
|
complement C3
|
multiple interactions decreases activity
|
EXP ISO
|
Progesterone inhibits the reaction [Estradiol affects the expression of C3 mRNA]; Progesterone inhibits the reaction [Ethinyl Estradiol results in increased expression of C3 mRNA] Progesterone results in decreased activity of C3 protein Progesterone inhibits the reaction [C3 protein results in increased phosphorylation of PRKCA protein]; Progesterone inhibits the reaction [C3 protein results in increased phosphorylation of PRKCZ protein]
|
CTD |
PMID:11566438 PMID:18615583 PMID:24777823 |
|
NCBI chr 9:2,174,412...2,201,339
Ensembl chr 9:2,174,412...2,201,339
|
|
| G
|
C5ar2
|
complement C5a receptor 2
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of C5AR2 mRNA; Progesterone results in decreased expression of C5AR2 protein
|
CTD |
PMID:18615583 |
|
NCBI chr 1:86,058,557...86,073,583
Ensembl chr 1:86,057,256...86,061,372
|
|
| G
|
Ca12
|
carbonic anhydrase 12
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of CA12 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 8:67,274,739...67,330,428
Ensembl chr 8:76,169,815...76,225,465
|
|
| G
|
Ca3
|
carbonic anhydrase 3
|
affects expression
|
ISO
|
Progesterone affects the expression of CAR3 mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr 2:88,491,666...88,501,299
Ensembl chr 2:88,491,670...88,500,524
|
|
| G
|
Cacna1c
|
calcium voltage-gated channel subunit alpha1 C
|
increases expression
|
EXP
|
Progesterone results in increased expression of CACNA1C mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr 4:153,431,169...154,051,932
Ensembl chr 4:153,436,427...154,051,762
|
|
| G
|
Cacna1d
|
calcium voltage-gated channel subunit alpha1 D
|
increases expression
|
ISO
|
Progesterone results in increased expression of CACNA1D mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr16:5,233,682...5,527,549
Ensembl chr16:5,233,690...5,674,692
|
|
| G
|
Cacna1g
|
calcium voltage-gated channel subunit alpha1 G
|
multiple interactions increases expression
|
ISO EXP
|
[Progesterone co-treated with Estradiol] results in decreased expression of CACNA1G mRNA Progesterone results in increased expression of CACNA1G mRNA
|
CTD |
PMID:17404688 PMID:20726854 |
|
NCBI chr10:79,354,998...79,422,960
Ensembl chr10:79,851,896...79,919,634
|
|
| G
|
Cacna2d1
|
calcium voltage-gated channel auxiliary subunit alpha2delta 1
|
increases expression
|
ISO
|
Progesterone results in increased expression of CACNA2D1 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 4:19,902,324...20,330,287
Ensembl chr 4:19,905,764...20,330,147
|
|
| G
|
Cadm1
|
cell adhesion molecule 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of CADM1 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 8:56,744,374...57,075,264
Ensembl chr 8:56,744,372...57,080,192
|
|
| G
|
Cadps2
|
calcium dependent secretion activator 2
|
increases expression
|
ISO
|
Progesterone results in increased expression of CADPS2 mRNA
|
CTD |
PMID:21540246 |
|
NCBI chr 4:52,746,054...53,275,252
Ensembl chr 4:52,746,065...53,275,004
|
|
| G
|
Calb1
|
calbindin 1
|
multiple interactions increases expression decreases expression
|
ISO
|
CALB1 protein inhibits the reaction [Progesterone results in increased expression of BAX protein]; CALB1 protein inhibits the reaction [Progesterone results in increased expression of CASP3 protein]; NCOA2 protein affects the reaction [Progesterone results in decreased expression of CALB1 mRNA] Progesterone results in increased expression of CALB1 mRNA
|
CTD |
PMID:17556502 PMID:21882229 PMID:22238285 |
|
NCBI chr 5:34,172,612...34,199,555
Ensembl chr 5:34,172,664...34,200,160
|
|
| G
|
Calca
|
calcitonin-related polypeptide alpha
|
increases activity multiple interactions increases expression
|
EXP ISO
|
Progesterone results in increased activity of CALCA protein [Estradiol co-treated with Progesterone co-treated with Corn Oil] results in increased expression of CALCA mRNA Progesterone results in increased expression of CALCA mRNA
|
CTD |
PMID:9887042 PMID:21770760 PMID:32186404 |
|
NCBI chr 1:178,312,636...178,317,588
Ensembl chr 1:178,312,638...178,317,529
|
|
| G
|
Calcrl
|
calcitonin receptor like receptor
|
increases expression
|
EXP
|
Progesterone results in increased expression of CALCRL mRNA
|
CTD |
PMID:15469997 |
|
NCBI chr 3:89,835,071...89,932,616
Ensembl chr 3:89,835,077...89,887,350
|
|
| G
|
Calhm6
|
calcium homeostasis modulator family member 6
|
increases expression
|
ISO
|
Progesterone results in increased expression of CALHM6 mRNA
|
CTD |
PMID:21540246 |
|
NCBI chr20:26,638,721...26,640,466
Ensembl chr20:26,638,722...26,640,408
|
|
| G
|
Calm1
|
calmodulin 1
|
increases expression
|
EXP
|
Progesterone results in increased expression of CALM1 mRNA
|
CTD |
PMID:16376865 |
|
NCBI chr 6:125,217,191...125,227,855
Ensembl chr 6:125,217,246...125,225,381
|
|
| G
|
Calm2
|
calmodulin 2
|
multiple interactions decreases expression
|
ISO
|
Mifepristone inhibits the reaction [Progesterone results in decreased expression of CALM2 mRNA]
|
CTD |
PMID:27264040 PMID:31566189 |
|
NCBI chr 6:12,845,170...12,857,830
Ensembl chr15:64,519,554...64,520,657 Ensembl chr 6:64,519,554...64,520,657
|
|
| G
|
Caln1
|
calneuron 1
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of CALN1 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr12:31,447,964...31,939,847
|
|
| G
|
Calr
|
calreticulin
|
increases expression decreases expression
|
EXP ISO
|
Progesterone results in increased expression of CALR mRNA Progesterone results in decreased expression of CALR protein
|
CTD |
PMID:16376865 PMID:19460863 |
|
NCBI chr19:40,213,367...40,218,262
Ensembl chr19:40,213,239...40,219,236
|
|
| G
|
Caly
|
calcyon neuron-specific vesicular protein
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of CALY mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 1:194,862,671...194,873,861
Ensembl chr 1:204,292,318...204,303,196
|
|
| G
|
Camk1d
|
calcium/calmodulin-dependent protein kinase ID
|
increases expression
|
ISO
|
Progesterone results in increased expression of CAMK1D mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr17:77,491,191...77,892,018
Ensembl chr17:77,491,220...77,892,012
|
|
| G
|
Camk2b
|
calcium/calmodulin-dependent protein kinase II beta
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of CAMK2B mRNA
|
CTD |
PMID:21540246 |
|
NCBI chr14:80,845,206...80,934,172
Ensembl chr14:85,059,191...85,148,485
|
|
| G
|
Camk2d
|
calcium/calmodulin-dependent protein kinase II delta
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of CAMK2D mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 2:217,698,324...217,961,898
Ensembl chr 2:217,698,551...217,960,276
|
|
| G
|
Camk2n1
|
calcium/calmodulin-dependent protein kinase II inhibitor 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of CAMK2N1 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 5:150,674,819...150,676,600
Ensembl chr 5:155,957,878...155,961,058
|
|
| G
|
Camp
|
cathelicidin antimicrobial peptide
|
increases expression
|
ISO
|
Progesterone results in increased expression of CAMP mRNA; Progesterone results in increased expression of CAMP protein
|
CTD |
PMID:17701593 |
|
NCBI chr 8:109,841,729...109,843,543
Ensembl chr 8:118,720,184...118,721,998
|
|
| G
|
Cap2
|
cyclase associated actin cytoskeleton regulatory protein 2
|
increases expression
|
EXP
|
Progesterone results in increased expression of CAP2 mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr17:18,054,234...18,203,453
Ensembl chr17:18,261,646...18,409,563
|
|
| G
|
Capn6
|
calpain 6
|
increases expression multiple interactions
|
ISO
|
Progesterone results in increased expression of CAPN6 mRNA [Estradiol co-treated with Progesterone] results in increased expression of CAPN6 mRNA; [Progesterone co-treated with Estradiol] results in increased expression of CAPN6 mRNA
|
CTD |
PMID:17404688 PMID:20660070 |
|
NCBI chr X:112,177,467...112,202,178
Ensembl chr X:112,177,467...112,202,178
|
|
| G
|
Capn9
|
calpain 9
|
multiple interactions decreases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of CAPN9 mRNA Progesterone results in decreased expression of CAPN9 mRNA
|
CTD |
PMID:19693291 |
|
NCBI chr19:69,446,847...69,483,810
Ensembl chr19:69,446,847...69,483,810
|
|
| G
|
Car2
|
carbonic anhydrase 2
|
multiple interactions decreases expression increases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of CA2 mRNA; [Progesterone co-treated with Estradiol] results in decreased expression of CA2 mRNA Progesterone results in decreased expression of CAR2 mRNA Progesterone results in increased expression of CA2 mRNA Progesterone results in decreased expression of CA2 mRNA
|
CTD |
PMID:17404688 PMID:18037150 PMID:18497975 PMID:20660070 PMID:22238285 |
|
NCBI chr 2:88,462,883...88,478,012
Ensembl chr 2:88,462,872...88,478,064
|
|
| G
|
Casp3
|
caspase 3
|
multiple interactions increases expression increases activity
|
ISO EXP
|
[CCN2 gene mutant form results in increased abundance of Progesterone] which results in increased expression of CASP3 mRNA; CALB1 protein inhibits the reaction [Progesterone results in increased expression of CASP3 protein]; S100G protein inhibits the reaction [Progesterone results in increased expression of CASP3 protein] Progesterone results in increased activity of CASP3 protein [Estradiol co-treated with Progesterone co-treated with Methylnitrosourea] results in decreased activity of CASP3 protein; [Methylnitrosourea co-treated with Progesterone co-treated with Estradiol] results in decreased expression of CASP3 mRNA; [Methylnitrosourea co-treated with Progesterone] results in decreased expression of CASP3 mRNA; BCL2L1 mRNA affects the reaction [Progesterone inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]]; Mifepristone inhibits the reaction [Progesterone inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]]; Progesterone inhibits the reaction [Dicumarol promotes the reaction [Doxorubicin results in increased activity of CASP3 protein]]; Progesterone inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]; Progesterone inhibits the reaction [Isoproterenol results in increased activity of CASP3 protein]; Progesterone inhibits the reaction [Palmitates results in increased activity of CASP3 protein]
|
CTD |
PMID:20726854 PMID:20732338 PMID:21868453 PMID:21882229 PMID:21933904 PMID:21947872 PMID:22465879 PMID:26915917 More...
|
|
NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
|
|
| G
|
Casp4
|
caspase 4
|
increases expression
|
EXP
|
Progesterone results in increased expression of CASP4 mRNA
|
CTD |
PMID:21770760 |
|
NCBI chr 8:10,883,817...10,919,978
Ensembl chr 8:10,883,769...10,920,727
|
|
| G
|
Casp8
|
caspase 8
|
increases expression multiple interactions
|
ISO EXP
|
Progesterone results in increased expression of CASP8 mRNA Progesterone inhibits the reaction [Cisplatin results in increased activity of CASP8 protein] [Estradiol co-treated with Progesterone co-treated with Methylnitrosourea] results in decreased activity of CASP8 protein; [Methylnitrosourea co-treated with Progesterone co-treated with Estradiol] results in decreased expression of CASP8 mRNA
|
CTD |
PMID:20732338 PMID:21549006 PMID:21770760 PMID:22465879 PMID:23482746 |
|
NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:67,758,033...67,806,699
|
|
| G
|
Casp9
|
caspase 9
|
multiple interactions
|
EXP ISO
|
[Methylnitrosourea co-treated with Progesterone co-treated with Estradiol] results in decreased expression of CASP9 mRNA Progesterone inhibits the reaction [Cisplatin results in increased activity of CASP9 protein]
|
CTD |
PMID:20732338 PMID:23482746 |
|
Ensembl chr 5:159,391,188...159,409,648
|
|
| G
|
Catsperb
|
cation channel sperm associated auxiliary subunit beta
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of CATSPERB mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr 6:120,418,606...120,713,160
Ensembl chr 6:126,147,645...126,472,079
|
|
| G
|
Cav1
|
caveolin 1
|
increases expression multiple interactions
|
ISO
|
Progesterone results in increased expression of CAV1 mRNA Mifepristone inhibits the reaction [Progesterone results in increased expression of CAV1 mRNA]
|
CTD |
PMID:15674352 |
|
NCBI chr 4:46,606,538...46,639,616
Ensembl chr 4:46,600,738...46,639,740
|
|
| G
|
Cav3
|
caveolin 3
|
multiple interactions
|
ISO
|
CAV3 mutant form inhibits the reaction [Progesterone results in decreased expression of GNAI3 protein]; CAV3 mutant form inhibits the reaction [Progesterone results in increased expression of GNAS protein]
|
CTD |
PMID:19221014 |
|
NCBI chr 4:145,582,168...145,598,142
Ensembl chr 4:147,137,797...147,153,967
|
|
| G
|
Cbfa2t3
|
CBFA2/RUNX1 partner transcriptional co-repressor 3
|
affects expression
|
ISO
|
Progesterone affects the expression of CBFA2T3 mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr19:67,584,319...67,658,533
Ensembl chr19:67,589,258...67,658,136
|
|
| G
|
Cblc
|
Cbl proto-oncogene C
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of CBLC mRNA
|
CTD |
PMID:21540246 |
|
NCBI chr 1:88,567,930...88,584,709
Ensembl chr 1:88,567,932...88,584,709
|
|
| G
|
Cblif
|
cobalamin binding intrinsic factor
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of CBLIF mRNA
|
CTD |
PMID:19693291 |
|
NCBI chr 1:218,030,756...218,045,004
Ensembl chr 1:218,030,731...218,045,117
|
|
| G
|
Cbr3
|
carbonyl reductase 3
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of CBR3 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr11:46,478,295...46,486,555
Ensembl chr11:46,478,274...46,486,558
|
|
| G
|
Cbs
|
cystathionine beta synthase
|
increases expression
|
ISO
|
Progesterone results in increased expression of CBS mRNA
|
CTD |
PMID:21795739 PMID:22238285 |
|
NCBI chr20:9,709,394...9,733,925
Ensembl chr20:9,709,395...9,734,066
|
|
| G
|
Ccdc3
|
coiled-coil domain containing 3
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of CCDC3 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr17:73,031,891...73,135,173
Ensembl chr17:77,944,977...78,044,470
|
|
| G
|
Ccdc68
|
coiled-coil domain containing 68
|
increases expression
|
ISO
|
Progesterone results in increased expression of CCDC68 mRNA
|
CTD |
PMID:21795739 |
|
NCBI chr18:65,817,232...65,859,529
Ensembl chr18:65,786,926...65,859,526
|
|
| G
|
Ccdc71l
|
coiled-coil domain containing 71-like
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of CCDC71L mRNA
|
CTD |
PMID:20864642 |
|
NCBI chr 6:54,687,474...54,691,566
Ensembl chr 6:54,617,540...55,014,344
|
|
| G
|
Cck
|
cholecystokinin
|
multiple interactions decreases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of CCK mRNA Progesterone results in decreased expression of CCK mRNA
|
CTD |
PMID:19693291 PMID:22238285 |
|
NCBI chr 8:130,031,012...130,037,702
Ensembl chr 8:130,031,013...130,037,686
|
|
| G
|
Ccl2
|
C-C motif chemokine ligand 2
|
multiple interactions decreases expression affects expression
|
ISO EXP
|
Progesterone inhibits the reaction [[Lipopolysaccharides co-treated with HMGB1 protein] results in increased expression of CCL2 protein] Progesterone results in decreased expression of CCL2 mRNA; Progesterone results in decreased expression of CCL2 protein Progesterone affects the expression of CCL2 mRNA [Estradiol co-treated with Progesterone] results in decreased expression of CCL2 mRNA; [Estradiol co-treated with Progesterone] results in decreased expression of CCL2 protein
|
CTD |
PMID:17251523 PMID:20726854 PMID:21277368 PMID:21549006 PMID:22014880 |
|
NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875
|
|
| G
|
Ccl3
|
C-C motif chemokine ligand 3
|
multiple interactions
|
EXP
|
[Estradiol co-treated with Progesterone] results in increased expression of CCL3 mRNA
|
CTD |
PMID:21277368 |
|
NCBI chr10:68,948,889...68,950,439
Ensembl chr10:68,948,889...68,950,439
|
|
| G
|
Ccl5
|
C-C motif chemokine ligand 5
|
multiple interactions increases expression
|
ISO EXP
|
[Progesterone co-treated with Estradiol] results in decreased expression of CCL5 mRNA; TGFB1 protein promotes the reaction [Progesterone results in increased expression of CCL5 mRNA] [Estradiol co-treated with Progesterone] results in decreased expression of CCL5 mRNA; [Estradiol co-treated with Progesterone] results in decreased expression of CCL5 protein
|
CTD |
PMID:17404688 PMID:21277368 PMID:21768398 |
|
NCBI chr10:68,820,330...68,824,906
Ensembl chr10:68,738,651...68,824,884
|
|
| G
|
Ccn2
|
cellular communication network factor 2
|
affects expression increases expression increases abundance multiple interactions
|
ISO
|
Progesterone affects the expression of CCN2 mRNA Progesterone results in increased expression of CCN2 mRNA CCN2 gene mutant form results in increased abundance of Progesterone [CCN2 gene mutant form results in increased abundance of Progesterone] which results in increased expression of CASP3 mRNA
|
CTD |
PMID:17251523 PMID:21868453 PMID:22238285 |
|
NCBI chr 1:22,621,498...22,624,614
Ensembl chr 1:22,621,501...22,624,976
|
|
| G
|
Ccn3
|
cellular communication network factor 3
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of CCN3 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 7:87,983,788...87,990,810
Ensembl chr 7:87,982,216...87,994,581
|
|
| G
|
Ccn5
|
cellular communication network factor 5
|
decreases expression multiple interactions
|
ISO
|
Progesterone results in decreased expression of CCN5 mRNA [Estradiol co-treated with Progesterone] results in decreased expression of CCN5 mRNA; [Progesterone co-treated with Estradiol] results in decreased expression of CCN5 mRNA
|
CTD |
PMID:17404688 PMID:18692832 PMID:20660070 |
|
NCBI chr 3:172,910,670...172,922,064
Ensembl chr 3:172,910,681...172,922,062
|
|
| G
|
Ccna1
|
cyclin A1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of CCNA1 mRNA; [Progesterone co-treated with Estradiol] results in increased expression of CCNA1 mRNA
|
CTD |
PMID:17404688 PMID:20660070 |
|
NCBI chr 2:141,383,352...141,428,205
Ensembl chr 2:141,382,468...141,393,300
|
|
| G
|
Ccna2
|
cyclin A2
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of CCNA2 mRNA; Lithium Chloride inhibits the reaction [Progesterone inhibits the reaction [Estradiol results in increased expression of CCNA2 protein]]; Progesterone inhibits the reaction [Estradiol results in increased expression of CCNA2 protein]
|
CTD |
PMID:15845746 PMID:19693291 |
|
NCBI chr 2:121,355,363...121,361,762
Ensembl chr 2:121,355,363...121,361,701
|
|
| G
|
Ccnb1
|
cyclin B1
|
decreases expression increases expression
|
ISO EXP
|
Progesterone results in decreased expression of CCNB1 mRNA Progesterone results in increased expression of CCNB1 mRNA
|
CTD |
PMID:18037150 PMID:18070364 PMID:19000923 PMID:20726854 |
|
NCBI chr 2:33,646,252...33,655,225
Ensembl chr 2:33,646,252...33,655,225
|
|
| G
|
Ccnb2
|
cyclin B2
|
increases expression multiple interactions decreases expression
|
ISO
|
Progesterone results in increased expression of CCNB2 mRNA [Estradiol co-treated with Progesterone] results in increased expression of CCNB2 mRNA Progesterone results in decreased expression of CCNB2 mRNA
|
CTD |
PMID:18070364 PMID:19693291 PMID:21795739 |
|
NCBI chr 8:79,968,459...79,981,717
Ensembl chr 8:79,968,465...79,981,682
|
|
| G
|
Ccnd1
|
cyclin D1
|
increases expression multiple interactions decreases expression
|
ISO EXP
|
Progesterone results in increased expression of CCND1 mRNA [Methylnitrosourea co-treated with Progesterone co-treated with Estradiol] results in increased expression of CCND1 mRNA; [Methylnitrosourea co-treated with Progesterone co-treated with Estradiol] results in increased expression of CCND1 protein; [Methylnitrosourea co-treated with Progesterone] results in increased expression of CCND1 mRNA; [Methylnitrosourea co-treated with Progesterone] results in increased expression of CCND1 protein Progesterone results in decreased expression of CCND1 mRNA [Estradiol co-treated with Progesterone] results in decreased expression of CCND1 mRNA [Estradiol co-treated with Progesterone] results in increased expression of CCND1 mRNA; Lithium Chloride inhibits the reaction [Progesterone inhibits the reaction [Estradiol affects the localization of CCND1 protein]]; Progesterone inhibits the reaction [Estradiol affects the localization of CCND1 protein]
|
CTD |
PMID:15845746 PMID:16888808 PMID:16966611 PMID:17170212 PMID:18070364 PMID:18556351 PMID:19847363 PMID:20660070 PMID:20732338 PMID:20864642 More...
|
|
NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810
|
|
| G
|
Ccnd3
|
cyclin D3
|
increases expression
|
EXP
|
Progesterone results in increased expression of CCND3 mRNA
|
CTD |
PMID:17170212 |
|
NCBI chr 9:20,891,696...20,987,199
Ensembl chr 9:20,891,704...20,987,033
|
|
| G
|
Ccne1
|
cyclin E1
|
decreases expression increases expression
|
ISO
|
Progesterone results in decreased expression of CCNE1 mRNA Progesterone results in increased expression of CCNE1 mRNA
|
CTD |
PMID:16966611 PMID:19847363 |
|
NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:99,918,674...99,927,822
|
|
| G
|
Ccng1
|
cyclin G1
|
multiple interactions increases expression
|
ISO EXP
|
[Progesterone co-treated with Estradiol] results in increased expression of CCNG1 mRNA; PGR gene mutant form inhibits the reaction [Progesterone results in increased expression of CCNG1 mRNA]
|
CTD |
PMID:15661853 PMID:20726854 |
|
NCBI chr10:25,678,503...25,684,876
Ensembl chr10:25,677,885...25,683,766
|
|
| G
|
Ccni
|
cyclin I
|
affects expression
|
ISO
|
Progesterone affects the expression of CCNI mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr14:15,164,047...15,186,885
Ensembl chr14:15,164,095...15,186,885
|
|
| G
|
Ccr1
|
C-C motif chemokine receptor 1
|
increases expression
|
EXP
|
Progesterone results in increased expression of CCR1 mRNA
|
CTD |
PMID:21770760 |
|
NCBI chr 8:132,433,711...132,439,266
Ensembl chr 8:132,431,592...132,439,374
|
|
| G
|
Cd14
|
CD14 molecule
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of CD14 mRNA
|
CTD |
PMID:21549006 |
|
NCBI chr18:28,609,558...28,611,409
Ensembl chr18:28,608,883...28,611,292
|
|
| G
|
Cd164
|
CD164 molecule
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of CD164 mRNA
|
CTD |
PMID:18556351 |
|
NCBI chr20:45,024,051...45,035,628
Ensembl chr20:46,606,107...46,638,649
|
|
| G
|
Cd180
|
CD180 molecule
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of CD180 mRNA
|
CTD |
PMID:19693291 |
|
NCBI chr 2:33,855,940...33,870,046
Ensembl chr 2:35,589,451...35,603,982
|
|
| G
|
Cd200
|
Cd200 molecule
|
increases expression decreases expression
|
ISO EXP
|
Progesterone results in increased expression of CD200 mRNA Progesterone results in decreased expression of CD200 mRNA
|
CTD |
PMID:20726854 PMID:22238285 |
|
NCBI chr11:68,916,200...68,943,570
Ensembl chr11:68,916,224...68,943,569
|
|
| G
|
Cd226
|
CD226 molecule
|
increases expression
|
ISO
|
Progesterone results in increased expression of CD226 mRNA
|
CTD |
PMID:20864642 |
|
NCBI chr18:84,723,330...84,819,836
Ensembl chr18:84,725,242...84,819,835
|
|
| G
|
Cd24
|
CD24 molecule
|
multiple interactions decreases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of CD24 mRNA Progesterone results in decreased expression of CD24 mRNA
|
CTD |
PMID:20660070 PMID:21795739 |
|
NCBI chr20:48,655,549...48,661,786
Ensembl chr20:48,655,805...48,661,785
|
|
| G
|
Cd247
|
Cd247 molecule
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of CD247 mRNA
|
CTD |
PMID:19693291 |
|
NCBI chr13:80,576,264...80,651,422
Ensembl chr13:80,576,202...80,655,248
|
|
| G
|
Cd302
|
CD302 molecule
|
increases expression
|
ISO
|
Progesterone results in increased expression of CD302 mRNA
|
CTD |
PMID:20864642 |
|
NCBI chr 3:65,131,017...65,164,737
Ensembl chr 3:65,113,102...65,164,737
|
|
| G
|
Cd36
|
CD36 molecule
|
increases expression
|
EXP
|
Progesterone results in increased expression of CD36 mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr 4:18,209,088...18,302,142
|
|
| G
|
Cd38
|
CD38 molecule
|
multiple interactions increases expression
|
ISO EXP
|
[Progesterone co-treated with TGFB1 protein] results in increased expression of CD38 mRNA Progesterone results in increased expression of CD38 mRNA
|
CTD |
PMID:21768398 PMID:21770760 |
|
NCBI chr14:71,384,532...71,424,794
Ensembl chr14:71,384,532...71,424,505
|
|
| G
|
Cd3e
|
CD3 epsilon subunit of T-cell receptor complex
|
multiple interactions
|
EXP
|
[Estradiol co-treated with Progesterone] results in decreased expression of CD3E mRNA; [Estradiol co-treated with Progesterone] results in decreased expression of CD3E protein
|
CTD |
PMID:21277368 |
|
NCBI chr 8:54,200,617...54,211,770
Ensembl chr 8:54,200,617...54,211,876
|
|
| G
|
Cd44
|
CD44 molecule
|
multiple interactions increases expression decreases expression
|
ISO EXP
|
[Progesterone co-treated with Estradiol] results in increased expression of CD44 mRNA Progesterone results in increased expression of CD44 mRNA Progesterone results in decreased expression of CD44 mRNA
|
CTD |
PMID:18692832 PMID:20226447 PMID:20726854 PMID:21770760 PMID:22238285 |
|
NCBI chr 3:109,610,824...109,699,776
Ensembl chr 3:109,612,054...109,699,424
|
|
| G
|
Cd52
|
CD52 molecule
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of CD52 mRNA
|
CTD |
PMID:19693291 |
|
NCBI chr 5:151,603,537...151,605,096
Ensembl chr 5:151,603,524...151,605,086
|
|
| G
|
Cd68
|
Cd68 molecule
|
multiple interactions
|
EXP
|
[Estradiol co-treated with Progesterone] results in decreased expression of CD68 mRNA
|
CTD |
PMID:21277368 |
|
NCBI chr10:54,880,562...54,882,441
Ensembl chr10:54,880,563...54,882,540
|
|
| G
|
Cd7
|
Cd7 molecule
|
affects expression
|
ISO
|
Progesterone affects the expression of CD7 mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr10:106,802,373...106,805,269
Ensembl chr10:106,802,383...106,805,294
|
|
| G
|
Cd80
|
Cd80 molecule
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of CD80 protein
|
CTD |
PMID:21856019 |
|
NCBI chr11:75,760,073...75,798,978
Ensembl chr11:75,760,147...75,797,540
|
|
| G
|
Cd83
|
CD83 molecule
|
decreases expression increases expression
|
ISO
|
Progesterone results in decreased expression of CD83 mRNA Progesterone results in increased expression of CD83 mRNA
|
CTD |
PMID:18037150 PMID:22238285 |
|
NCBI chr17:21,093,281...21,113,223
Ensembl chr17:21,093,281...21,113,047
|
|
| G
|
Cd86
|
CD86 molecule
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of CD86 protein
|
CTD |
PMID:21856019 |
|
NCBI chr11:77,647,565...77,706,178
Ensembl chr11:77,647,600...77,725,361
|
|
| G
|
Cd8b
|
CD8 subunit beta
|
affects expression
|
ISO
|
Progesterone affects the expression of CD8B1 mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr 4:104,870,911...104,886,838
Ensembl chr 4:104,870,893...104,886,868
|
|
| G
|
Cd96
|
CD96 molecule
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of CD96 mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr11:54,702,290...54,776,618
Ensembl chr11:68,164,872...68,241,937
|
|
| G
|
Cda
|
cytidine deaminase
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] affects the expression of CDA mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr 5:155,839,929...155,866,541
Ensembl chr 5:155,839,929...155,866,541
|
|
| G
|
Cdc14b
|
cell division cycle 14B
|
multiple interactions increases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of CDC14B mRNA; [Progesterone co-treated with Estradiol] results in increased expression of CDC14B mRNA Progesterone results in increased expression of CDC14B mRNA
|
CTD |
PMID:17404688 PMID:20660070 |
|
NCBI chr17:850,272...938,972
Ensembl chr17:850,390...971,164
|
|
| G
|
Cdc20
|
cell division cycle 20
|
increases expression decreases expression
|
ISO EXP
|
Progesterone results in increased expression of CDC20 mRNA Progesterone results in decreased expression of CDC20 mRNA
|
CTD |
PMID:18070364 PMID:19693291 PMID:20726854 |
|
NCBI chr 5:137,251,596...137,255,799
Ensembl chr 5:137,251,596...137,255,799
|
|
| G
|
Cdc25b
|
cell division cycle 25B
|
increases expression
|
ISO
|
Progesterone results in increased expression of CDC25B mRNA
|
CTD |
PMID:18497975 |
|
NCBI chr 3:138,860,148...138,870,287
Ensembl chr 3:138,860,130...138,870,492
|
|
| G
|
Cdc42ep3
|
CDC42 effector protein 3
|
increases expression
|
ISO
|
Progesterone results in increased expression of CDC42EP3 mRNA
|
CTD |
PMID:17404688 PMID:21795739 PMID:22238285 |
|
NCBI chr 6:21,463,081...21,483,553
Ensembl chr 6:21,461,762...21,508,540
|
|
| G
|
Cdc6
|
cell division cycle 6
|
increases expression
|
ISO
|
Progesterone results in increased expression of CDC6 mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr10:84,360,361...84,374,239
Ensembl chr10:84,360,381...84,374,241
|
|
| G
|
Cdca3
|
cell division cycle associated 3
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of CDCA3 mRNA
|
CTD |
PMID:21795739 |
|
NCBI chr 4:159,321,203...159,325,072
Ensembl chr 4:159,321,014...159,325,068
|
|
| G
|
Cdca7
|
cell division cycle associated 7
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of CDCA7 mRNA
|
CTD |
PMID:21795739 |
|
NCBI chr 3:77,730,315...77,740,950
Ensembl chr 3:77,729,970...77,740,947
|
|
| G
|
Cdh16
|
cadherin 16
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of CDH16 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr19:367,202...377,710
Ensembl chr19:367,274...388,934
|
|
| G
|
Cdh2
|
cadherin 2
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of CDH2 mRNA
|
CTD |
PMID:17556502 |
|
NCBI chr18:8,051,097...8,265,288
Ensembl chr18:8,051,097...8,265,288
|
|
| G
|
Cdh4
|
cadherin 4
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of CDH4 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 3:166,525,092...167,003,380
Ensembl chr 3:186,902,751...187,381,020
|
|
| G
|
Cdh5
|
cadherin 5
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of CDH5 mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr19:815,415...854,478
Ensembl chr19:822,464...860,822
|
|
| G
|
Cdh6
|
cadherin 6
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of CDH6 mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr 2:63,801,630...63,952,309
Ensembl chr 2:63,806,135...63,952,287
|
|
| G
|
Cdk1
|
cyclin-dependent kinase 1
|
increases expression decreases expression
|
ISO EXP
|
Progesterone results in increased expression of CDK1 mRNA Progesterone results in decreased expression of CDK1 mRNA
|
CTD |
PMID:18070364 PMID:20726854 |
|
NCBI chr20:19,265,252...19,280,456
Ensembl chr20:19,265,289...19,280,455
|
|
| G
|
Cdk19
|
cyclin-dependent kinase 19
|
increases expression
|
ISO
|
Progesterone results in increased expression of CDK19 mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr20:43,770,409...43,910,629
Ensembl chr20:45,324,862...45,465,121
|
|
| G
|
Cdk2
|
cyclin dependent kinase 2
|
multiple interactions increases expression decreases activity
|
ISO
|
Progesterone promotes the reaction [CDK2 protein binds to CDKN1A protein]; Progesterone promotes the reaction [CDK2 protein binds to CDKN1B protein] Progesterone results in increased expression of CDK2 mRNA Progesterone results in decreased activity of CDK2 protein
|
CTD |
PMID:18850315 PMID:19847363 |
|
NCBI chr 7:1,714,392...1,721,964
Ensembl chr 7:1,714,392...1,721,878
|
|
| G
|
Cdk4
|
cyclin-dependent kinase 4
|
increases expression
|
ISO
|
Progesterone results in increased expression of CDK4 mRNA
|
CTD |
PMID:19847363 |
|
NCBI chr 7:64,771,453...64,774,891
Ensembl chr 7:64,771,147...64,775,163
|
|
| G
|
Cdk5rap2
|
CDK5 regulatory subunit associated protein 2
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of CDK5RAP2 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 5:83,792,282...83,961,129
Ensembl chr 5:88,807,402...88,976,069
|
|
| G
|
Cdk8
|
cyclin-dependent kinase 8
|
increases expression
|
ISO
|
Progesterone results in increased expression of CDK8 mRNA
|
CTD |
PMID:16888808 |
|
NCBI chr12:8,737,198...8,805,026
Ensembl chr12:13,851,024...13,917,992
|
|
| G
|
Cdk9
|
cyclin-dependent kinase 9
|
increases expression
|
ISO
|
Progesterone results in increased expression of CDK9 mRNA
|
CTD |
PMID:16888808 |
|
NCBI chr 3:15,996,467...16,001,315
Ensembl chr 3:36,394,169...36,399,528
|
|
| G
|
Cdkl1
|
cyclin dependent kinase like 1
|
decreases expression multiple interactions
|
ISO
|
Progesterone results in decreased expression of CDKL1 mRNA NCOA2 protein affects the reaction [Progesterone results in decreased expression of CDKL1 mRNA]
|
CTD |
PMID:17556502 |
|
NCBI chr 6:93,960,157...94,005,207
Ensembl chr 6:93,959,911...94,006,115
|
|
| G
|
Cdkl2
|
cyclin dependent kinase like 2
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of CDKL2 mRNA
|
CTD |
PMID:16966611 |
|
NCBI chr14:16,027,381...16,063,257
Ensembl chr14:16,312,932...16,347,523
|
|
| G
|
Cdkn1a
|
cyclin-dependent kinase inhibitor 1A
|
multiple interactions increases expression
|
ISO
|
Progesterone promotes the reaction [CDK2 protein binds to CDKN1A protein]; TP53 mutant form inhibits the reaction [Progesterone results in increased expression of CDKN1A mRNA]; TP53 mutant form inhibits the reaction [Progesterone results in increased expression of CDKN1A protein] Progesterone results in increased expression of CDKN1A mRNA; Progesterone results in increased expression of CDKN1A protein
|
CTD |
PMID:18045962 PMID:18850315 |
|
NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969
|
|
| G
|
Cdkn1b
|
cyclin-dependent kinase inhibitor 1B
|
multiple interactions increases expression affects localization
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of CDKN1B mRNA; [Progesterone co-treated with Estradiol] results in increased expression of and results in increased stability of CDKN1B protein; FZR1 mutant form inhibits the reaction [Progesterone affects the localization of CDKN1B protein]; Progesterone promotes the reaction [CDK2 protein binds to CDKN1B protein]; TP53 mutant form inhibits the reaction [Progesterone results in increased expression of CDKN1B mRNA]; TP53 mutant form inhibits the reaction [Progesterone results in increased expression of CDKN1B protein] Progesterone results in increased expression of CDKN1B mRNA; Progesterone results in increased expression of CDKN1B protein
|
CTD |
PMID:18850315 PMID:22064387 PMID:23029392 |
|
NCBI chr 4:169,491,273...169,496,500
Ensembl chr 4:169,490,876...169,496,498
|
|
| G
|
Cdkn1c
|
cyclin-dependent kinase inhibitor 1C
|
multiple interactions increases expression
|
ISO EXP
|
[Estradiol co-treated with Progesterone] results in increased expression of CDKN1C mRNA Progesterone results in increased expression of CDKN1C mRNA
|
CTD |
PMID:20726854 PMID:22064387 |
|
NCBI chr 1:208,084,801...208,087,680
Ensembl chr 1:208,084,787...208,087,498
|
|
| G
|
Cdkn2aip
|
CDKN2A interacting protein
|
increases expression
|
ISO
|
Progesterone results in increased expression of CDKN2AIP mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr16:44,536,147...44,546,216
Ensembl chr16:51,268,896...51,274,049
|
|
| G
|
Cdkn2b
|
cyclin-dependent kinase inhibitor 2B
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of CDKN2B mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 5:109,123,308...109,134,906
Ensembl chr 5:109,114,322...109,134,855
|
|
| G
|
Cdkn2c
|
cyclin-dependent kinase inhibitor 2C
|
increases expression
|
ISO
|
Progesterone results in increased expression of CDKN2C mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr 5:129,639,736...129,645,564
Ensembl chr 5:129,639,736...129,644,891
|
|
| G
|
Cdkn3
|
cyclin-dependent kinase inhibitor 3
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of CDKN3 mRNA
|
CTD |
PMID:21795739 |
|
NCBI chr15:22,502,299...22,513,725
Ensembl chr15:22,502,382...22,513,722
|
|
| G
|
Cdo1
|
cysteine dioxygenase type 1
|
affects expression increases expression
|
ISO EXP
|
Progesterone affects the expression of CDO1 mRNA Progesterone results in increased expression of CDO1 mRNA
|
CTD |
PMID:17251523 PMID:20726854 |
|
NCBI chr18:41,619,076...41,633,719
Ensembl chr18:41,619,070...41,633,891
|
|
| G
|
Cdt1
|
chromatin licensing and DNA replication factor 1
|
multiple interactions
|
ISO
|
Progesterone inhibits the reaction [Estradiol results in increased expression of CDT1 protein]
|
CTD |
PMID:16966611 |
|
NCBI chr19:67,529,249...67,534,195
Ensembl chr19:67,529,201...67,534,194
|
|
| G
|
Ceacam1
|
CEA cell adhesion molecule 1
|
increases expression
|
ISO
|
Progesterone results in increased expression of CEACAM1 mRNA
|
CTD |
PMID:18692832 |
|
NCBI chr 1:90,171,401...90,187,810
Ensembl chr 1:90,171,401...90,187,798
|
|
| G
|
Ceacam6
|
CEA cell adhesion molecule 6
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of CEACAM6 mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr 1:80,416,531...80,434,668
Ensembl chr 1:89,544,400...89,562,552
|
|
| G
|
Cebpb
|
CCAAT/enhancer binding protein beta
|
increases response to substance decreases expression increases expression
|
ISO EXP
|
CEBPB protein results in increased susceptibility to Progesterone Progesterone results in decreased expression of CEBPB mRNA Progesterone results in increased expression of CEBPB mRNA
|
CTD |
PMID:20726854 PMID:21549006 PMID:23097472 |
|
NCBI chr 3:176,817,005...176,818,436
Ensembl chr 3:176,816,859...176,838,072
|
|
| G
|
Cebpd
|
CCAAT/enhancer binding protein delta
|
affects expression increases expression multiple interactions
|
ISO EXP
|
Progesterone affects the expression of CEBPD mRNA Progesterone results in increased expression of CEBPD mRNA [Estradiol co-treated with Progesterone] results in increased expression of CEBPD mRNA
|
CTD |
PMID:17251523 PMID:18037150 PMID:20660070 PMID:20726854 PMID:21795739 |
|
NCBI chr11:98,268,856...98,269,994
Ensembl chr11:98,265,651...98,280,824
|
|
| G
|
Cebpg
|
CCAAT/enhancer binding protein gamma
|
increases expression
|
ISO
|
Progesterone results in increased expression of CEBPG mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr 1:87,683,060...87,692,772
Ensembl chr 1:96,810,214...96,830,283
|
|
| G
|
Cemip
|
cell migration inducing hyaluronidase 1
|
multiple interactions
|
ISO
|
Progesterone inhibits the reaction [Estradiol results in increased expression of CEMIP mRNA]
|
CTD |
PMID:21795739 |
|
NCBI chr 1:147,316,052...147,471,552
Ensembl chr 1:147,316,052...147,471,768
|
|
| G
|
Cenpa
|
centromere protein A
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of CENPA mRNA
|
CTD |
PMID:21795739 |
|
NCBI chr 6:31,420,062...31,431,703
|
|
| G
|
Cenpf
|
centromere protein F
|
increases expression
|
ISO
|
Progesterone results in increased expression of CENPF mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr13:103,715,344...103,760,931
Ensembl chr13:103,715,344...103,760,886
|
|
| G
|
Cenpn
|
centromere protein N
|
increases expression
|
ISO
|
Progesterone results in increased expression of CENPN mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr19:44,971,265...44,994,019
Ensembl chr19:61,877,148...61,902,918
|
|
| G
|
Cenpq
|
centromere protein Q
|
increases expression
|
ISO
|
Progesterone results in increased expression of CENPQ mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr 9:19,957,122...19,972,807
Ensembl chr 9:27,454,252...27,469,366
|
|
| G
|
Cenpu
|
centromere protein U
|
increases expression decreases expression
|
ISO
|
Progesterone results in increased expression of CENPU mRNA Progesterone results in decreased expression of CENPU mRNA
|
CTD |
PMID:18070364 PMID:21795739 |
|
NCBI chr16:52,448,446...52,471,662
Ensembl chr16:52,425,096...52,471,662
|
|
| G
|
Cenpv
|
centromere protein V
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of CENPV mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr10:47,214,479...47,228,552
Ensembl chr10:47,713,778...47,727,679
|
|
| G
|
Cep131
|
centrosomal protein 131
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of CEP131 mRNA
|
CTD |
PMID:21453500 |
|
NCBI chr10:105,346,015...105,370,380
Ensembl chr10:105,844,433...105,868,797
|
|
| G
|
Cep15
|
centrosomal protein 15
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of CEP15 mRNA
|
CTD |
PMID:21453500 |
|
NCBI chr15:12,815,159...12,835,115
Ensembl chr15:15,247,932...15,265,475
|
|
| G
|
Cep162
|
centrosomal protein 162
|
increases expression
|
ISO
|
Progesterone results in increased expression of CEP162 mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr 8:88,149,726...88,208,249
Ensembl chr 8:97,029,677...97,088,207
|
|
| G
|
Cep55
|
centrosomal protein 55
|
increases expression decreases expression
|
ISO
|
Progesterone results in increased expression of CEP55 mRNA Progesterone results in decreased expression of CEP55 mRNA
|
CTD |
PMID:18070364 PMID:21795739 |
|
NCBI chr 1:245,245,272...245,260,835
Ensembl chr 1:245,245,306...245,260,890
|
|
| G
|
Cep57
|
centrosomal protein 57
|
increases expression
|
ISO
|
Progesterone results in increased expression of CEP57 mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr 8:10,669,588...10,689,257
Ensembl chr 8:18,932,808...18,970,890
|
|
| G
|
Cep76
|
centrosomal protein 76
|
increases expression
|
ISO
|
Progesterone results in increased expression of CEP76 mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr18:61,174,514...61,208,512
Ensembl chr18:63,443,746...63,478,358
|
|
| G
|
Cerk
|
ceramide kinase
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of CERK mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 7:119,105,674...119,149,885
Ensembl chr 7:119,105,674...119,148,570
|
|
| G
|
Cers3
|
ceramide synthase 3
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of CERS3 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 1:129,728,136...129,833,182
Ensembl chr 1:129,677,781...129,833,181
|
|
| G
|
Cers6
|
ceramide synthase 6
|
increases expression
|
ISO
|
Progesterone results in increased expression of CERS6 mRNA
|
CTD |
PMID:20864642 |
|
NCBI chr 3:74,038,520...74,287,544
Ensembl chr 3:74,038,851...74,287,544
|
|
| G
|
Ces4a
|
carboxylesterase 4A
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of CES4A mRNA
|
CTD |
PMID:21540246 |
|
NCBI chr19:49,921,643...49,942,838
Ensembl chr19:49,921,608...49,939,461
|
|
| G
|
Cfb
|
complement factor B
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of CFB mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr20:3,970,643...3,976,510
Ensembl chr20:3,955,776...3,981,740
|
|
| G
|
Cfd
|
complement factor D
|
affects expression
|
ISO
|
Progesterone affects the expression of CFD mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr 7:10,463,773...10,465,496
Ensembl chr 7:10,463,775...10,465,572
|
|
| G
|
Cfh
|
complement factor H
|
increases expression decreases expression
|
ISO EXP
|
Progesterone results in increased expression of CFH mRNA Progesterone results in decreased expression of CFH mRNA
|
CTD |
PMID:20726854 PMID:20864642 PMID:21795739 |
|
NCBI chr13:51,512,376...51,613,829
Ensembl chr13:54,062,531...54,164,532
|
|
| G
|
Cfhr1
|
complement factor H-related 1
|
increases expression
|
ISO
|
Progesterone results in increased expression of CFHR1 mRNA
|
CTD |
PMID:20864642 |
|
NCBI chr13:51,395,583...51,410,571
Ensembl chr13:53,919,927...53,961,303
|
|
| G
|
Cfi
|
complement factor I
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of CFI mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 2:221,062,206...221,104,790
Ensembl chr 2:221,062,212...221,104,786
|
|
| G
|
Cfl1
|
cofilin 1
|
multiple interactions
|
ISO
|
CFL1 protein affects the reaction [CGA protein results in increased secretion of Progesterone]
|
CTD |
PMID:20610540 |
|
NCBI chr 1:212,227,124...212,230,656
Ensembl chr 1:212,226,121...212,231,353
|
|
| G
|
Cflar
|
CASP8 and FADD-like apoptosis regulator
|
increases expression
|
EXP
|
Progesterone results in increased expression of CFLAR mRNA
|
CTD |
PMID:21770760 |
|
NCBI chr 9:67,679,502...67,747,226
Ensembl chr 9:67,679,559...67,726,434
|
|
| G
|
Cftr
|
CF transmembrane conductance regulator
|
multiple interactions decreases expression
|
ISO EXP
|
[Progesterone co-treated with Estradiol] results in decreased expression of CFTR mRNA [Genistein co-treated with estradiol-17-benzoate co-treated with Progesterone] results in increased expression of CFTR mRNA; [Genistein co-treated with estradiol-17-benzoate co-treated with Progesterone] results in increased expression of CFTR protein Progesterone results in decreased expression of CFTR mRNA; Progesterone results in decreased expression of CFTR protein
|
CTD |
PMID:15471937 PMID:17404688 PMID:26529183 |
|
NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:47,526,735...47,694,643
|
|
| G
|
Cga
|
glycoprotein hormones, alpha polypeptide
|
multiple interactions increases abundance increases secretion
|
EXP ISO
|
[[3,4',5-trimethoxystilbene co-treated with CGA protein] results in decreased expression of CYP17A1 protein] which results in increased secretion of Progesterone; [[resveratrol analog co-treated with CGA protein] results in decreased expression of CYP17A1 protein] which results in increased secretion of Progesterone; [[resveratrol co-treated with CGA protein] results in decreased expression of CYP17A1 protein] which results in increased secretion of Progesterone; ADM protein inhibits the reaction [CGA protein results in increased secretion of Progesterone]; bifenthrin analog inhibits the reaction [CGA protein results in increased abundance of Progesterone] [3,4',5-trimethoxystilbene co-treated with CGA protein] results in increased secretion of Progesterone; [CGA protein affects the secretion of Cyclic AMP] which results in increased secretion of Progesterone; [CGA protein co-treated with FSHB protein] results in increased abundance of Progesterone; [CGA protein co-treated with FSHB protein] results in increased secretion of Progesterone; [Resveratrol analog co-treated with CGA protein] results in increased secretion of Progesterone; [Resveratrol co-treated with CGA protein] results in increased secretion of Progesterone; [T0901317 co-treated with fatostatin] promotes the reaction [CGA protein results in increased secretion of Progesterone]; ADM protein modified form inhibits the reaction [ADM protein inhibits the reaction [CGA protein results in increased secretion of Progesterone]]; butylbenzyl phthalate inhibits the reaction [CGA protein results in increased secretion of Progesterone]; CFL1 protein affects the reaction [CGA protein results in increased secretion of Progesterone]; DDT inhibits the reaction [CGA protein results in increased secretion of Progesterone]; decabromobiphenyl ether inhibits the reaction [CGA protein results in increased secretion of Progesterone]; Dibutyl Phthalate inhibits the reaction [CGA protein results in increased secretion of Progesterone]; Diethylhexyl Phthalate inhibits the reaction [CGA protein results in increased secretion of Progesterone]; fatostatin promotes the reaction [CGA protein results in increased secretion of Progesterone]; T0901317 inhibits the reaction [[CGA protein co-treated with FSHB protein] results in increased abundance of Progesterone] lead acetate inhibits the reaction [CGA protein results in increased abundance of Progesterone]; mono-(2-ethylhexyl)phthalate inhibits the reaction [CGA protein results in increased abundance of Progesterone]
|
CTD |
PMID:11213355 PMID:12647776 PMID:18401014 PMID:19228890 PMID:19603415 PMID:20610540 PMID:20926582 PMID:21458522 PMID:21871944 PMID:23071612 PMID:25016925 PMID:27181934 PMID:29366778 PMID:31132478 PMID:33638691 PMID:34768887 More...
|
|
NCBI chr 5:54,283,109...54,295,464
Ensembl chr 5:54,235,019...54,295,464
|
|
| G
|
Ch25h
|
cholesterol 25-hydroxylase
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of CH25H mRNA
|
CTD |
PMID:21795739 PMID:22238285 |
|
NCBI chr 1:241,428,048...241,429,366
Ensembl chr 1:241,331,619...241,431,190
|
|
| G
|
Chac1
|
ChaC glutathione-specific gamma-glutamylcyclotransferase 1
|
increases expression
|
ISO
|
Progesterone results in increased expression of CHAC1 mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr 3:126,796,131...126,799,352
Ensembl chr 3:126,796,024...126,799,361
|
|
| G
|
Chaf1a
|
chromatin assembly factor 1 subunit A
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of CHAF1A mRNA
|
CTD |
PMID:16966611 |
|
NCBI chr 9:961,225...987,825
Ensembl chr 9:961,084...987,868
|
|
| G
|
Chaf1b
|
chromatin assembly factor 1 subunit B
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of CHAF1B mRNA
|
CTD |
PMID:16966611 |
|
NCBI chr11:46,670,560...46,690,739
Ensembl chr11:46,670,630...46,690,733
|
|
| G
|
Chat
|
choline O-acetyltransferase
|
multiple interactions
|
ISO
|
Progesterone inhibits the reaction [VPS54 gene mutant form results in decreased activity of CHAT protein]; Progesterone inhibits the reaction [VPS54 gene mutant form results in decreased expression of CHAT protein]; Progesterone inhibits the reaction [VPS54 mutant form results in decreased expression of CHAT protein]
|
CTD |
PMID:17052708 PMID:19693665 |
|
NCBI chr16:7,657,362...7,717,093
Ensembl chr16:7,663,665...7,723,416
|
|
| G
|
Chchd10
|
coiled-coil-helix-coiled-coil-helix domain containing 10
|
affects expression
|
ISO
|
Progesterone affects the expression of CHCHD10 mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr20:12,725,839...12,727,638
Ensembl chr20:12,725,277...12,745,677
|
|
| G
|
Chek1
|
checkpoint kinase 1
|
decreases expression multiple interactions increases phosphorylation
|
EXP ISO
|
Progesterone results in decreased expression of CHEK1 mRNA Mifepristone inhibits the reaction [Progesterone results in increased phosphorylation of CHEK1 protein]
|
CTD |
PMID:20726854 PMID:22403396 |
|
NCBI chr 8:44,609,417...44,629,867
Ensembl chr 8:44,609,417...44,629,359
|
|
| G
|
Chga
|
chromogranin A
|
multiple interactions decreases expression
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of CHGA mRNA Progesterone results in decreased expression of CHGA mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr 6:121,696,051...121,707,399
Ensembl chr 6:127,460,854...127,472,237
|
|
| G
|
Chi3l1
|
chitinase 3 like 1
|
multiple interactions increases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of CHI3L1 mRNA Progesterone results in increased expression of CHI3L1 mRNA
|
CTD |
PMID:18497975 PMID:20660070 |
|
NCBI chr13:45,641,802...45,649,787
Ensembl chr13:48,193,800...48,201,825
|
|
| G
|
Chn1
|
chimerin 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of CHN1 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 3:78,917,329...79,084,040
Ensembl chr 3:78,917,329...79,084,197
|
|
| G
|
Chn2
|
chimerin 2
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of CHN2 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 4:84,478,989...84,738,068
Ensembl chr 4:84,704,862...84,738,068
|
|
| G
|
Chordc1
|
cysteine and histidine rich domain containing 1
|
increases expression
|
ISO
|
Progesterone results in increased expression of CHORDC1 mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr 8:15,374,356...15,398,436
Ensembl chr 8:23,650,865...23,677,696
|
|
| G
|
Chpt1
|
choline phosphotransferase 1
|
increases expression
|
ISO
|
Progesterone results in increased expression of CHPT1 mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr 7:24,753,880...24,802,529
Ensembl chr 7:24,750,343...24,802,521
|
|
| G
|
Chrdl1
|
chordin-like 1
|
increases expression
|
ISO
|
Progesterone results in increased expression of CHRDL1 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr X:106,889,125...106,992,937
Ensembl chr X:111,685,866...111,789,661
|
|
| G
|
Chrdl2
|
chordin-like 2
|
increases expression
|
ISO
|
Progesterone results in increased expression of CHRDL2 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 1:163,755,316...163,782,758
Ensembl chr 1:163,755,316...163,782,757
|
|
| G
|
Chrm1
|
cholinergic receptor, muscarinic 1
|
multiple interactions
|
EXP
|
Progesterone inhibits the reaction [Acetylcholine binds to CHRM1 protein]; Progesterone inhibits the reaction [Quinuclidinyl Benzilate binds to CHRM1 protein]
|
CTD |
PMID:15900516 |
|
NCBI chr 1:214,996,180...215,012,136
Ensembl chr 1:214,995,872...215,020,602
|
|
| G
|
Chrm3
|
cholinergic receptor, muscarinic 3
|
multiple interactions
|
EXP
|
Progesterone inhibits the reaction [Acetylcholine binds to CHRM3 protein]; Progesterone inhibits the reaction [Quinuclidinyl Benzilate binds to CHRM3 protein]
|
CTD |
PMID:15900516 |
|
NCBI chr17:64,696,549...65,158,622
Ensembl chr17:64,696,066...65,173,304
|
|
| G
|
Chrna4
|
cholinergic receptor nicotinic alpha 4 subunit
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Acetylcholine] results in decreased activity of [CHRNA4 protein binds to CHRNB2 protein]
|
CTD |
PMID:11517245 |
|
NCBI chr 3:188,506,802...188,535,558
Ensembl chr 3:188,501,209...188,535,105
|
|
| G
|
Chrna5
|
cholinergic receptor nicotinic alpha 5 subunit
|
increases expression
|
ISO
|
Progesterone results in increased expression of CHRNA5 protein Progesterone results in increased expression of CHRNA5 mRNA
|
CTD |
PMID:19220484 |
|
NCBI chr 8:55,369,794...55,398,526
Ensembl chr 8:64,265,879...64,294,233
|
|
| G
|
Chrnb2
|
cholinergic receptor nicotinic beta 2 subunit
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Acetylcholine] results in decreased activity of [CHRNA4 protein binds to CHRNB2 protein]
|
CTD |
PMID:11517245 |
|
NCBI chr 2:177,479,091...177,487,306
Ensembl chr 2:177,479,091...177,491,326
|
|
| G
|
Chrne
|
cholinergic receptor nicotinic epsilon subunit
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of CHRNE mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr10:55,829,835...55,838,853
Ensembl chr10:55,829,836...55,834,154
|
|
| G
|
Chst11
|
carbohydrate sulfotransferase 11
|
increases expression
|
ISO
|
Progesterone results in increased expression of CHST11 mRNA
|
CTD |
PMID:21540246 |
|
NCBI chr 7:22,412,121...22,630,577
Ensembl chr 7:22,415,686...22,630,441
|
|
| G
|
Chst15
|
carbohydrate sulfotransferase 15
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of CHST15 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 1:196,458,978...196,540,088
Ensembl chr 1:196,460,425...196,491,444
|
|
| G
|
Chst4
|
carbohydrate sulfotransferase 4
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of CHST4 mRNA
|
CTD |
PMID:21540246 |
|
NCBI chr19:54,900,914...54,911,735
Ensembl chr19:54,882,719...54,916,648
|
|
| G
|
Chst7
|
carbohydrate sulfotransferase 7
|
multiple interactions increases expression
|
ISO
|
[Progesterone co-treated with Estradiol] results in increased expression of CHST7 mRNA Progesterone results in increased expression of CHST7 mRNA
|
CTD |
PMID:17404688 PMID:20864642 |
|
NCBI chr X:2,396,260...2,432,828
Ensembl chr X:4,938,757...4,986,907
|
|
| G
|
Chst9
|
carbohydrate sulfotransferase 9
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of CHST9 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr18:6,850,874...7,125,222
Ensembl chr18:6,851,831...7,125,161
|
|
| G
|
Chsy3
|
chondroitin sulfate synthase 3
|
multiple interactions increases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of CHSY3 mRNA Progesterone results in increased expression of CHSY3 mRNA
|
CTD |
PMID:20660070 PMID:20864642 |
|
NCBI chr18:54,842,260...55,096,008
Ensembl chr18:54,842,180...55,095,981
|
|
| G
|
Cidec
|
cell death-inducing DFFA-like effector c
|
affects expression
|
ISO
|
Progesterone affects the expression of CIDEC mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr 4:148,124,924...148,137,806
Ensembl chr 4:148,124,925...148,137,806
|
|
| G
|
Cilp
|
cartilage intermediate layer protein
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of CILP mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 8:74,671,696...74,687,420
Ensembl chr 8:74,671,534...74,687,409
|
|
| G
|
Cish
|
cytokine inducible SH2-containing protein
|
multiple interactions
|
EXP
|
Progesterone inhibits the reaction [Estrogens results in increased expression of CISH mRNA]; Progesterone inhibits the reaction [PRL protein results in increased expression of CISH mRNA]
|
CTD |
PMID:18325991 |
|
NCBI chr 8:116,850,969...116,855,917
Ensembl chr 8:116,850,773...116,855,986
|
|
| G
|
Cited1
|
Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1
|
increases expression
|
ISO
|
Progesterone results in increased expression of CITED1 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr X:67,350,376...67,355,072
Ensembl chr X:71,390,331...71,393,649
|
|
| G
|
Cited2
|
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of CITED2 mRNA; [Progesterone co-treated with Estradiol] results in increased expression of CITED2 mRNA [Progesterone results in increased activity of PGR protein] which results in increased expression of CITED2 mRNA
|
CTD |
PMID:15845616 PMID:17404688 PMID:20660070 |
|
NCBI chr 1:14,132,303...14,134,746
Ensembl chr 1:14,103,457...14,134,782
|
|
| G
|
Cited4
|
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4
|
increases expression
|
ISO
|
Progesterone results in increased expression of CITED4 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 5:139,532,165...139,533,056
Ensembl chr 5:139,531,584...139,533,361
|
|
| G
|
Ckap2
|
cytoskeleton associated protein 2
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of CKAP2 mRNA
|
CTD |
PMID:21795739 |
|
NCBI chr16:76,542,114...76,567,297
Ensembl chr16:76,542,104...76,567,352
|
|
| G
|
Ckb
|
creatine kinase B
|
multiple interactions affects expression increases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of CKB mRNA; [Progesterone co-treated with Estradiol] results in increased expression of CKB mRNA Progesterone affects the expression of CKB mRNA Progesterone results in increased expression of CKB mRNA
|
CTD |
PMID:17251523 PMID:17404688 PMID:20660070 |
|
NCBI chr 6:136,550,583...136,553,464
Ensembl chr 6:136,549,844...136,553,478
|
|
| G
|
Ckm
|
creatine kinase, M-type
|
increases expression
|
EXP
|
Progesterone results in increased expression of CKM mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr 1:88,189,382...88,199,717
Ensembl chr 1:88,189,485...88,199,719
|
|
| G
|
Cks1b
|
CDC28 protein kinase regulatory subunit 1B
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of CKS1B protein [Estradiol co-treated with Progesterone] results in increased expression of CKS1B mRNA
|
CTD |
PMID:18556351 PMID:23029392 |
|
NCBI chr 2:177,130,751...177,135,333
Ensembl chr 2:177,130,777...177,135,365
|
|
| G
|
Clca1
|
chloride channel accessory 1
|
affects expression decreases expression
|
ISO
|
Progesterone affects the expression of CLCA1 mRNA Progesterone results in decreased expression of CLCA1 mRNA
|
CTD |
PMID:17251523 PMID:22238285 |
|
NCBI chr 2:236,599,022...236,624,714
Ensembl chr 2:236,599,022...236,624,714
|
|
| G
|
Clca4
|
chloride channel accessory 4
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of CLCA4 mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr 2:236,543,975...236,565,096
Ensembl chr 2:236,544,201...236,563,435
|
|
| G
|
Clcn4
|
chloride voltage-gated channel 4
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in increased expression of CLCN4 mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr X:27,290,769...27,356,967
Ensembl chr X:27,290,868...27,356,939
|
|
| G
|
Cldn1
|
claudin 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of CLDN1 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr11:87,926,376...87,941,533
Ensembl chr11:87,926,337...87,941,529
|
|
| G
|
Cldn23
|
claudin 23
|
multiple interactions increases expression
|
ISO
|
NCOA2 protein affects the reaction [Progesterone results in increased expression of CLDN23 mRNA]
|
CTD |
PMID:17556502 |
|
NCBI chr16:63,117,045...63,118,769
Ensembl chr16:63,116,781...63,118,957
|
|
| G
|
Cldn3
|
claudin 3
|
affects expression
|
ISO
|
Progesterone affects the expression of CLDN3 mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr12:27,345,075...27,346,547
Ensembl chr12:27,345,076...27,348,841
|
|
| G
|
Cldn4
|
claudin 4
|
decreases expression affects expression
|
ISO
|
Progesterone results in decreased expression of CLDN4 mRNA Progesterone affects the expression of CLDN4 mRNA
|
CTD |
PMID:17251523 PMID:18037150 |
|
NCBI chr12:27,388,160...27,389,958
Ensembl chr12:27,387,981...27,389,958
|
|
| G
|
Cldn5
|
claudin 5
|
increases expression multiple interactions
|
ISO
|
Progesterone results in increased expression of CLDN5 mRNA [Estradiol co-treated with Progesterone] results in increased expression of CLDN5 mRNA
|
CTD |
PMID:17404688 PMID:20660070 |
|
NCBI chr11:95,717,172...95,718,598
Ensembl chr11:95,717,176...95,719,322
|
|
| G
|
Cldn6
|
claudin 6
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of CLDN6 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr10:12,710,302...12,713,987
Ensembl chr10:13,213,956...13,218,581
|
|
| G
|
Cldn8
|
claudin 8
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of CLDN8 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr11:41,362,081...41,364,330
|
|
| G
|
Cldnd1
|
claudin domain containing 1
|
affects expression
|
ISO
|
Progesterone affects the expression of CLDND1 mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr11:41,883,120...41,889,471
Ensembl chr11:55,352,321...55,358,907
|
|
| G
|
Clec3b
|
C-type lectin domain family 3, member B
|
multiple interactions increases expression
|
ISO
|
[Progesterone co-treated with Estradiol] results in increased expression of CLEC3B mRNA Progesterone results in increased expression of CLEC3B mRNA
|
CTD |
PMID:20226447 |
|
NCBI chr 8:131,687,575...131,693,292
|
|
| G
|
Clec4d
|
C-type lectin domain family 4, member D
|
affects expression
|
ISO
|
Progesterone affects the expression of CLEC4D mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr 4:158,275,287...158,286,978
Ensembl chr 4:158,275,341...158,287,055
|
|
| G
|
Clgn
|
calmegin
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of CLGN mRNA
|
CTD |
PMID:21540246 |
|
NCBI chr19:41,601,568...41,633,207
Ensembl chr19:41,601,568...41,633,325
|
|
| G
|
Clic2
|
chloride intracellular channel 2
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of CLIC2 mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr20:149,337...164,375
Ensembl chr20:154,255...169,648
|
|
| G
|
Clic3
|
chloride intracellular channel 3
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of CLIC3 mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr 3:28,670,176...28,672,166
Ensembl chr 3:28,670,229...28,675,723
|
|
| G
|
Clic4
|
chloride intracellular channel 4
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of CLIC4 mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr 5:152,737,371...152,797,118
Ensembl chr 5:152,737,371...152,797,118
|
|
| G
|
Clic6
|
chloride intracellular channel 6
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of CLIC6 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr11:45,223,715...45,266,261
Ensembl chr11:45,223,669...45,267,344
|
|
| G
|
Clmn
|
calmin
|
multiple interactions decreases expression
|
ISO
|
NCOA2 protein affects the reaction [Progesterone results in decreased expression of CLMN mRNA]
|
CTD |
PMID:17556502 |
|
NCBI chr 6:129,470,613...129,572,079
Ensembl chr 6:129,478,149...129,572,027
|
|
| G
|
Clstn2
|
calsyntenin 2
|
increases expression
|
EXP ISO
|
Progesterone results in increased expression of CLSTN2 mRNA
|
CTD |
PMID:20726854 PMID:22238285 |
|
NCBI chr 8:106,899,894...107,516,402
Ensembl chr 8:106,899,894...107,040,053
|
|
| G
|
Clu
|
clusterin
|
increases expression
|
EXP
|
Progesterone results in increased expression of CLU mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr15:44,336,619...44,375,861
Ensembl chr15:44,359,914...44,375,860
|
|
| G
|
Cmbl
|
carboxymethylenebutenolidase homolog
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of CMBL mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 2:84,280,128...84,301,878
Ensembl chr 2:84,242,512...84,301,880
|
|
| G
|
Cmklr1
|
chemerin chemokine-like receptor 1
|
decreases expression
|
EXP
|
Progesterone results in decreased expression of CMKLR1 mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr12:48,634,929...48,687,833
Ensembl chr12:48,634,003...48,691,458
|
|
| G
|
Cmpk2
|
cytidine/uridine monophosphate kinase 2
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of CMPK2 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 6:48,802,150...48,813,652
Ensembl chr 6:48,802,321...48,813,652
|
|
| G
|
Cmtm3
|
CKLF-like MARVEL transmembrane domain containing 3
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of CMTM3 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr19:629,000...637,152
Ensembl chr19:628,895...636,225
|
|
| G
|
Cndp2
|
carnosine dipeptidase 2
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of CNDP2 mRNA
|
CTD |
PMID:21540246 |
|
NCBI chr18:78,039,924...78,057,030
Ensembl chr18:80,314,801...80,331,900
|
|
| G
|
Cnga1
|
cyclic nucleotide gated channel subunit alpha 1
|
increases expression
|
ISO
|
Progesterone results in increased expression of CNGA1 mRNA
|
CTD |
PMID:18497975 |
|
NCBI chr14:35,920,948...35,959,065
Ensembl chr14:35,926,854...35,959,056
|
|
| G
|
Cnih3
|
cornichon family AMPA receptor auxiliary protein 3
|
multiple interactions decreases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of CNIH3 mRNA; [Progesterone co-treated with Estradiol] results in decreased expression of CNIH3 mRNA Progesterone results in decreased expression of CNIH3 mRNA
|
CTD |
PMID:17404688 PMID:20660070 |
|
NCBI chr13:93,016,707...93,208,168
Ensembl chr13:95,598,998...95,772,064
|
|
| G
|
Cnn1
|
calponin 1
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of CNN1 mRNA
|
CTD |
PMID:21795739 |
|
NCBI chr 8:28,908,437...28,917,099
Ensembl chr 8:28,908,330...28,919,482
|
|
| G
|
Cnot7
|
CCR4-NOT transcription complex, subunit 7
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of CNOT7 mRNA
|
CTD |
PMID:21453500 |
|
NCBI chr16:51,775,416...51,794,581
Ensembl chr16:58,478,900...58,498,046
|
|
| G
|
Cnp
|
2',3'-cyclic nucleotide 3' phosphodiesterase
|
increases expression
|
EXP
|
Progesterone results in increased expression of CNP mRNA
|
CTD |
PMID:19853640 |
|
NCBI chr10:85,511,164...85,517,723
Ensembl chr10:86,011,495...86,018,063
|
|
| G
|
Cnr1
|
cannabinoid receptor 1
|
multiple interactions increases expression
|
ISO
|
[Progesterone co-treated with Estradiol] results in increased expression of CNR1 mRNA Progesterone results in increased expression of CNR1 mRNA
|
CTD |
PMID:17404688 PMID:20864642 |
|
NCBI chr 5:53,204,867...53,230,396
Ensembl chr 5:53,204,260...53,239,252
|
|
| G
|
Cntn1
|
contactin 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of CNTN1 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 7:125,142,638...125,440,397
Ensembl chr 7:125,142,696...125,440,391
|
|
| G
|
Cntn3
|
contactin 3
|
increases expression
|
ISO
|
Progesterone results in increased expression of CNTN3 mRNA
|
CTD |
PMID:21795739 |
|
NCBI chr 4:134,841,268...135,214,460
Ensembl chr 4:136,398,572...136,770,717
|
|
| G
|
Cntnap2
|
contactin associated protein 2
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of CNTNAP2 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 4:75,109,358...77,366,258
Ensembl chr 4:75,109,858...77,366,258
|
|
| G
|
Cntnap3
|
contactin associated protein family member 3
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of CNTNAP3 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr17:267,379...455,478
Ensembl chr17:273,137...461,233
|
|
| G
|
Coch
|
cochlin
|
increases expression
|
ISO
|
Progesterone results in increased expression of COCH mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 6:74,766,485...74,780,504
Ensembl chr 6:74,766,419...74,780,502
|
|
| G
|
Col11a1
|
collagen type XI alpha 1 chain
|
decreases expression multiple interactions
|
ISO
|
Progesterone results in decreased expression of COL11A1 mRNA [Progesterone co-treated with Estradiol] results in decreased expression of COL11A1 mRNA
|
CTD |
PMID:18070364 PMID:20226447 |
|
NCBI chr 2:204,509,136...204,702,264
Ensembl chr 2:204,509,136...204,702,264
|
|
| G
|
Col12a1
|
collagen type XII alpha 1 chain
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in increased expression of COL12A1 mRNA
|
CTD |
PMID:20226447 |
|
NCBI chr 8:89,427,834...89,545,886
Ensembl chr 8:89,427,834...89,545,711
|
|
| G
|
Col13a1
|
collagen type XIII alpha 1 chain
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of COL13A1 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr20:30,326,744...30,466,800
Ensembl chr20:30,326,744...30,466,800
|
|
| G
|
Col14a1
|
collagen type XIV alpha 1 chain
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of COL14A1 mRNA
|
CTD |
PMID:20226447 |
|
NCBI chr 7:86,722,093...86,937,215
Ensembl chr 7:88,611,828...88,826,938
|
|
| G
|
Col15a1
|
collagen type XV alpha 1 chain
|
multiple interactions increases expression
|
ISO
|
[Progesterone co-treated with Estradiol] results in increased expression of COL15A1 mRNA Progesterone results in increased expression of COL15A1 mRNA
|
CTD |
PMID:20226447 |
|
NCBI chr 5:66,297,546...66,403,172
Ensembl chr 5:66,297,461...66,403,170
|
|
| G
|
Col16a1
|
collagen type XVI alpha 1 chain
|
decreases expression multiple interactions
|
ISO
|
Progesterone results in decreased expression of COL16A1 mRNA [Progesterone co-treated with Estradiol] results in decreased expression of COL16A1 mRNA
|
CTD |
PMID:18070364 PMID:20226447 |
|
NCBI chr 5:142,388,376...142,442,825
Ensembl chr 5:147,672,601...147,727,011
|
|
| G
|
Col1a1
|
collagen type I alpha 1 chain
|
decreases expression multiple interactions affects expression
|
ISO
|
Progesterone results in decreased expression of COL1A1 mRNA [Estradiol co-treated with Progesterone] results in decreased expression of COL1A1 mRNA Progesterone affects the expression of COL1A1 mRNA
|
CTD |
PMID:17251523 PMID:18070364 PMID:19693291 |
|
NCBI chr10:80,380,458...80,397,461
Ensembl chr10:80,380,453...80,397,460
|
|
| G
|
Col1a2
|
collagen type I alpha 2 chain
|
multiple interactions increases expression decreases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of COL1A2 mRNA Progesterone results in increased expression of COL1A2 mRNA Progesterone results in decreased expression of COL1A2 mRNA
|
CTD |
PMID:18070364 PMID:18692832 PMID:20660070 PMID:21540246 |
|
NCBI chr 4:33,518,557...33,553,484
Ensembl chr 4:33,518,420...33,553,995
|
|
| G
|
Col23a1
|
collagen type XXIII alpha 1 chain
|
increases expression
|
ISO
|
Progesterone results in increased expression of COL23A1 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr10:36,050,327...36,337,279
Ensembl chr10:36,050,259...36,337,897
|
|
| G
|
Col3a1
|
collagen type III alpha 1 chain
|
affects expression
|
ISO
|
Progesterone affects the expression of COL3A1 protein
|
CTD |
PMID:20864640 |
|
NCBI chr 9:54,866,646...54,902,578
Ensembl chr 9:54,866,632...54,903,232
|
|
| G
|
Col4a1
|
collagen type IV alpha 1 chain
|
decreases expression increases expression
|
ISO
|
Progesterone results in decreased expression of COL4A1 mRNA Progesterone results in increased expression of COL4A1 mRNA
|
CTD |
PMID:18070364 PMID:20864642 |
|
NCBI chr16:84,885,597...84,996,482
Ensembl chr16:84,885,597...84,996,482
|
|
| G
|
Col5a2
|
collagen type V alpha 2 chain
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of COL5A2 mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr 9:54,940,768...55,090,151
Ensembl chr 9:54,940,764...55,090,150
|
|
| G
|
Col6a1
|
collagen type VI alpha 1 chain
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of COL6A1 mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr20:11,905,690...11,924,111
Ensembl chr20:11,905,457...11,924,107
|
|
| G
|
Col6a3
|
collagen type VI alpha 3 chain
|
affects expression
|
ISO
|
Progesterone affects the expression of COL6A3 protein
|
CTD |
PMID:20864640 |
|
NCBI chr 9:91,361,578...91,439,434
Ensembl chr 9:98,809,171...98,886,990
|
|
| G
|
Col7a1
|
collagen type VII alpha 1 chain
|
affects expression
|
ISO
|
Progesterone affects the expression of COL7A1 mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr 8:109,604,877...109,637,249
Ensembl chr 8:118,483,364...118,517,439
|
|
| G
|
Col8a1
|
collagen type VIII alpha 1 chain
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of COL8A1 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr11:42,776,851...42,906,432
Ensembl chr11:56,369,868...56,376,229
|
|
| G
|
Col8a2
|
collagen type VIII alpha 2 chain
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of COL8A2 mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr 5:138,586,201...138,613,627
Ensembl chr 5:143,870,742...143,897,884
|
|
| G
|
Colec12
|
collectin sub-family member 12
|
increases expression
|
ISO
|
Progesterone results in increased expression of COLEC12 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr18:732,950...920,620
Ensembl chr18:1,005,741...1,195,297
|
|
| G
|
Comt
|
catechol-O-methyltransferase
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of COMT protein
|
CTD |
PMID:17138778 |
|
NCBI chr11:96,072,371...96,091,956
Ensembl chr11:96,072,489...96,092,533
|
|
| G
|
Cops7a
|
COP9 signalosome subunit 7A
|
affects expression
|
ISO
|
Progesterone affects the expression of COPS7A mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr 4:157,766,626...157,792,632
Ensembl chr 4:159,452,897...159,460,315
|
|
| G
|
Corin
|
corin, serine peptidase
|
increases expression
|
ISO
|
Progesterone results in increased expression of CORIN mRNA
|
CTD |
PMID:20864642 PMID:21795739 |
|
NCBI chr14:36,034,613...36,264,671
Ensembl chr14:36,034,993...36,264,649
|
|
| G
|
Coro6
|
coronin 6
|
increases expression
|
EXP
|
Progesterone results in increased expression of CORO6 mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr10:62,808,172...62,817,788
Ensembl chr10:62,809,689...62,817,787
|
|
| G
|
Cotl1
|
coactosin-like F-actin binding protein 1
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of COTL1 mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr19:64,780,309...64,814,629
Ensembl chr19:64,780,322...64,814,840
|
|
| G
|
Cox4i1
|
cytochrome c oxidase subunit 4i1
|
increases abundance
|
ISO
|
COX4I1 protein results in increased abundance of Progesterone
|
CTD |
PMID:21558439 |
|
NCBI chr19:65,630,383...65,636,623
Ensembl chr19:65,630,432...65,636,624
|
|
| G
|
Cox6a2
|
cytochrome c oxidase subunit 6A2
|
increases expression
|
EXP
|
Progesterone results in increased expression of COX6A2 mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr 1:192,218,970...192,221,188
Ensembl chr 1:192,218,970...192,219,716
|
|
| G
|
Cox6b1
|
cytochrome c oxidase subunit 6B1
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of COX6B1 mRNA
|
CTD |
PMID:19693291 |
|
NCBI chr 1:95,002,513...95,011,516
Ensembl chr 1:95,001,707...95,011,431 Ensembl chr 5:95,001,707...95,011,431
|
|
| G
|
Cox7a1
|
cytochrome c oxidase subunit 7A1
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of COX7A1 mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr 1:94,549,663...94,572,330
Ensembl chr 1:94,569,216...94,570,889
|
|
| G
|
Cox8b
|
cytochrome c oxidase, subunit VIIIb
|
increases expression
|
EXP
|
Progesterone results in increased expression of COX8H mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr 1:205,406,813...205,408,273
Ensembl chr 1:205,406,813...205,408,311
|
|
| G
|
Cp
|
ceruloplasmin
|
affects expression increases expression multiple interactions
|
ISO EXP
|
Progesterone affects the expression of CP mRNA Progesterone results in increased expression of CP mRNA Mifepristone inhibits the reaction [Progesterone affects the expression of CP mRNA]
|
CTD |
PMID:17251523 PMID:20726854 PMID:22414680 |
|
NCBI chr 2:104,368,336...104,427,119
Ensembl chr 2:104,368,456...104,427,087
|
|
| G
|
Cpeb2
|
cytoplasmic polyadenylation element binding protein 2
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of CPEB2 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr14:71,999,958...72,056,012
Ensembl chr14:72,002,072...72,052,263
|
|
| G
|
Cped1
|
cadherin-like and PC-esterase domain containing 1
|
increases expression
|
ISO
|
Progesterone results in increased expression of CPED1 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 4:50,516,712...50,789,651
Ensembl chr 4:51,482,545...51,755,442
|
|
| G
|
Cpm
|
carboxypeptidase M
|
decreases expression increases expression multiple interactions
|
ISO
|
Progesterone results in decreased expression of CPM mRNA Progesterone results in increased expression of CPM mRNA [Estradiol co-treated with Progesterone] results in decreased expression of CPM mRNA
|
CTD |
PMID:17404688 PMID:18070364 PMID:20660070 PMID:20864642 |
|
NCBI chr 7:55,111,599...55,172,114
Ensembl chr 7:55,111,599...55,172,114
|
|
| G
|
Cpq
|
carboxypeptidase Q
|
affects response to substance
|
ISO
|
CPQ gene SNP affects the susceptibility to Progesterone
|
CTD |
PMID:25622337 |
|
NCBI chr 7:64,264,025...64,830,867
Ensembl chr 7:66,149,377...66,716,137
|
|
| G
|
Cpt1b
|
carnitine palmitoyltransferase 1B
|
increases expression
|
EXP
|
Progesterone results in increased expression of CPT1B mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr 7:122,370,974...122,380,473
Ensembl chr 7:122,370,444...122,380,036
|
|
| G
|
Cpxm1
|
carboxypeptidase X (M14 family), member 1
|
affects expression
|
ISO
|
Progesterone affects the expression of CPXM1 mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr 3:138,041,645...138,048,443
Ensembl chr 3:138,041,645...138,048,857
|
|
| G
|
Cpz
|
carboxypeptidase Z
|
multiple interactions increases expression
|
ISO EXP
|
[Progesterone co-treated with Estradiol] results in decreased expression of CPZ mRNA Progesterone results in increased expression of CPZ mRNA
|
CTD |
PMID:17404688 PMID:20726854 |
|
NCBI chr14:75,223,692...75,246,946
Ensembl chr14:79,448,139...79,471,556
|
|
| G
|
Crabp1
|
cellular retinoic acid binding protein 1
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of CRABP1 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 8:55,138,363...55,159,360
Ensembl chr 8:64,047,060...64,055,470
|
|
| G
|
Crabp2
|
cellular retinoic acid binding protein 2
|
multiple interactions decreases expression
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of CRABP2 mRNA Progesterone results in decreased expression of CRABP2 mRNA
|
CTD |
PMID:17404688 PMID:22238285 |
|
NCBI chr 2:175,714,862...175,719,208
Ensembl chr 2:175,707,312...175,728,385
|
|
| G
|
Creb1
|
cAMP responsive element binding protein 1
|
decreases expression
|
EXP
|
Progesterone results in decreased expression of CREB1 mRNA
|
CTD |
PMID:21371490 |
|
NCBI chr 9:73,397,333...73,466,339
Ensembl chr 9:73,397,306...73,466,339
|
|
| G
|
Creb5
|
cAMP responsive element binding protein 5
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of CREB5 mRNA
|
CTD |
PMID:21795739 |
|
NCBI chr 4:83,723,587...84,124,786
Ensembl chr 4:83,723,194...84,120,793
|
|
| G
|
Creg1
|
cellular repressor of E1A-stimulated genes 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of CREG1 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr13:80,552,779...80,565,272
Ensembl chr13:80,549,933...80,565,272
|
|
| G
|
Creld2
|
cysteine-rich with EGF-like domains 2
|
affects expression
|
ISO
|
Progesterone affects the expression of CRELD2 mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr 7:119,909,626...119,916,556
Ensembl chr 7:121,788,745...121,796,228
|
|
| G
|
Crh
|
corticotropin releasing hormone
|
multiple interactions increases secretion decreases abundance
|
ISO EXP
|
CRH protein inhibits the reaction [Go 6976 results in increased abundance of Progesterone]; Progesterone promotes the reaction [[CRHR1 protein binds to and results in increased activity of CRH protein] which results in increased abundance of Cyclic AMP]; Progesterone promotes the reaction [CRHR1 protein binds to and results in increased activity of CRH protein] CRH protein results in increased secretion of Progesterone CRH protein results in decreased abundance of Progesterone
|
CTD |
PMID:17170093 PMID:20702571 PMID:23133512 |
|
NCBI chr 2:104,059,184...104,061,048
Ensembl chr 2:104,058,770...104,061,386
|
|
| G
|
Crhr1
|
corticotropin releasing hormone receptor 1
|
multiple interactions increases expression
|
ISO
|
Progesterone promotes the reaction [[CRHR1 protein binds to and results in increased activity of CRH protein] which results in increased abundance of Cyclic AMP]; Progesterone promotes the reaction [CRHR1 protein binds to and results in increased activity of CRH protein] Progesterone results in increased expression of CRHR1 mRNA
|
CTD |
PMID:20702571 |
|
NCBI chr10:89,040,186...89,083,481
Ensembl chr10:89,540,192...89,583,466
|
|
| G
|
Crip1
|
cysteine rich protein 1
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of CRIP1 mRNA
|
CTD |
PMID:21540246 |
|
NCBI chr 6:138,047,801...138,055,672
Ensembl chr 6:138,047,801...138,055,672
|
|
| G
|
Crispld2
|
cysteine-rich secretory protein LCCL domain containing 2
|
multiple interactions increases expression
|
ISO EXP
|
[Progesterone co-treated with Estradiol] results in increased expression of CRISPLD2 mRNA Progesterone results in increased expression of CRISPLD2 mRNA
|
CTD |
PMID:17404688 PMID:20726854 PMID:20864642 PMID:21795739 |
|
NCBI chr19:64,961,764...65,020,099
Ensembl chr19:64,961,771...65,020,349
|
|
| G
|
Crlf1
|
cytokine receptor-like factor 1
|
multiple interactions increases expression
|
ISO
|
[Progesterone co-treated with Estradiol] results in increased expression of CRLF1 mRNA Progesterone results in increased expression of CRLF1 mRNA
|
CTD |
PMID:17404688 PMID:19693291 |
|
NCBI chr16:18,924,722...18,936,049
Ensembl chr16:18,957,956...18,969,970
|
|
| G
|
Crtam
|
cytotoxic and regulatory T cell molecule
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of CRTAM mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 8:50,237,210...50,274,472
Ensembl chr 8:50,237,210...50,274,472
|
|
| G
|
Cryab
|
crystallin, alpha B
|
multiple interactions increases expression
|
ISO EXP
|
[Progesterone co-treated with Estradiol] results in increased expression of CRYAB mRNA Progesterone results in increased expression of CRYAB mRNA
|
CTD |
PMID:17404688 PMID:20726854 |
|
NCBI chr 8:51,093,441...51,099,161
Ensembl chr 8:59,989,814...59,995,528
|
|
| G
|
Crybg2
|
crystallin beta-gamma domain containing 2
|
increases expression decreases expression
|
ISO
|
Progesterone results in increased expression of CRYBG2 mRNA Progesterone results in decreased expression of CRYBG2 mRNA
|
CTD |
PMID:17404688 PMID:21540246 |
|
NCBI chr 5:146,286,406...146,318,417
Ensembl chr 5:151,570,540...151,602,163
|
|
| G
|
Crybg3
|
crystallin beta-gamma domain containing 3
|
increases expression
|
ISO
|
Progesterone results in increased expression of CRYBG3 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr11:40,749,198...40,861,753
Ensembl chr11:54,208,444...54,330,960
|
|
| G
|
Csf2ra
|
colony stimulating factor 2 receptor subunit alpha
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in increased expression of CSF2RA mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr14:113,219...118,808
Ensembl chr14:113,225...118,117
|
|
| G
|
Csf3
|
colony stimulating factor 3
|
multiple interactions increases expression
|
ISO
|
[Progesterone co-treated with Estradiol] results in increased expression of CSF3 mRNA Progesterone results in increased expression of CSF3 mRNA
|
CTD |
PMID:17404688 PMID:21549006 |
|
NCBI chr10:84,157,485...84,159,860
Ensembl chr10:84,157,211...84,159,860
|
|
| G
|
Csk
|
C-terminal Src kinase
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of CSK mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr 8:58,029,748...58,048,742
Ensembl chr 8:66,925,651...66,930,274
|
|
| G
|
Csmd2
|
CUB and Sushi multiple domains 2
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of CSMD2 mRNA
|
CTD |
PMID:21453500 |
|
NCBI chr 5:140,342,352...140,912,422
Ensembl chr 5:145,626,845...146,196,812
|
|
| G
|
Cspg5
|
chondroitin sulfate proteoglycan 5
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of CSPG5 mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr 8:110,220,506...110,234,766
Ensembl chr 8:119,098,925...119,143,907
|
|
| G
|
Csrnp2
|
cysteine and serine rich nuclear protein 2
|
increases expression
|
ISO
|
Progesterone results in increased expression of CSRNP2 mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr 7:131,594,232...131,610,075
Ensembl chr 7:133,473,027...133,488,868
|
|
| G
|
Csrp2
|
cysteine and glycine-rich protein 2
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of CSRP2 mRNA
|
CTD |
PMID:21795739 |
|
NCBI chr 7:48,235,415...48,254,049
Ensembl chr 7:48,235,383...48,266,238
|
|
| G
|
Csrp3
|
cysteine and glycine rich protein 3
|
increases expression
|
EXP
|
Progesterone results in increased expression of CSRP3 mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr 1:98,528,067...98,546,647
Ensembl chr 1:107,664,338...107,682,916
|
|
| G
|
Cst8
|
cystatin 8
|
affects response to substance
|
ISO
|
CST8 protein affects the susceptibility to Progesterone
|
CTD |
PMID:20811015 |
|
NCBI chr 3:136,244,586...136,255,412
Ensembl chr 3:156,697,767...156,724,636
|
|
| G
|
Csta
|
cystatin A
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of CSTA mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr11:78,125,813...78,136,818
Ensembl chr11:78,125,800...78,136,822
|
|
| G
|
Ctbp1
|
C-terminal binding protein 1
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of CTBP1 mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr14:77,455,580...77,482,821
Ensembl chr14:81,679,765...81,707,554
|
|
| G
|
Ctdspl
|
CTD small phosphatase like
|
increases expression
|
ISO
|
Progesterone results in increased expression of CTDSPL mRNA
|
CTD |
PMID:18497975 |
|
NCBI chr 8:118,642,729...118,767,238
Ensembl chr 8:127,520,499...127,644,999
|
|
| G
|
Cth
|
cystathionine gamma-lyase
|
increases expression
|
ISO
|
Progesterone results in increased expression of CTH mRNA
|
CTD |
PMID:21795739 |
|
NCBI chr 2:249,634,731...249,661,066
Ensembl chr 2:249,634,731...249,661,066
|
|
| G
|
Ctnna2
|
catenin alpha 2
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of CTNNA2 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 4:110,852,265...112,001,351
Ensembl chr 4:110,852,265...112,001,365
|
|
| G
|
Ctnnb1
|
catenin beta 1
|
increases expression decreases abundance increases response to substance
|
EXP ISO
|
Progesterone results in increased expression of CTNNB1 protein CTNNB1 protein results in decreased abundance of Progesterone CTNNB1 protein results in increased susceptibility to Progesterone
|
CTD |
PMID:17170212 PMID:20610534 PMID:22958837 |
|
NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:129,517,545...129,544,662
|
|
| G
|
Ctnnd2
|
catenin delta 2
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of CTNND2 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 2:82,879,469...83,727,409
Ensembl chr 2:82,879,469...83,727,409
|
|
| G
|
Ctsd
|
cathepsin D
|
increases expression
|
ISO
|
Progesterone results in increased expression of CTSD mRNA
|
CTD |
PMID:18497975 |
|
NCBI chr 1:206,956,945...206,968,821
Ensembl chr 1:206,956,944...206,968,821
|
|
| G
|
Ctse
|
cathepsin E
|
affects expression increases expression
|
ISO
|
Progesterone affects the expression of CTSE mRNA Progesterone results in increased expression of CTSE mRNA
|
CTD |
PMID:17251523 PMID:17404688 |
|
NCBI chr13:45,644,168...45,666,722
Ensembl chr13:45,644,147...45,666,722
|
|
| G
|
Ctsh
|
cathepsin H
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of CTSH mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 8:90,608,941...90,627,824
Ensembl chr 8:99,488,874...99,509,181
|
|
| G
|
Ctsk
|
cathepsin K
|
increases expression
|
EXP
|
Progesterone results in increased expression of CTSK mRNA
|
CTD |
PMID:21770760 |
|
NCBI chr 2:183,058,586...183,069,551
Ensembl chr 2:185,747,165...185,765,582
|
|
| G
|
Ctsw
|
cathepsin W
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of CTSW mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr 1:212,201,904...212,208,028
Ensembl chr 1:212,201,904...212,205,292
|
|
| G
|
Cux2
|
cut-like homeobox 2
|
multiple interactions increases expression decreases expression
|
ISO
|
[Progesterone co-treated with Estradiol] results in increased expression of CUX2 mRNA Progesterone results in increased expression of CUX2 mRNA Progesterone results in decreased expression of CUX2 mRNA
|
CTD |
PMID:17404688 PMID:18070364 |
|
NCBI chr12:40,168,402...40,368,303
Ensembl chr12:40,149,292...40,366,528
|
|
| G
|
Cwh43
|
cell wall biogenesis 43 C-terminal homolog
|
decreases expression increases expression
|
ISO
|
Progesterone results in decreased expression of CWH43 mRNA Progesterone results in increased expression of CWH43 mRNA
|
CTD |
PMID:21540246 PMID:22238285 |
|
NCBI chr14:35,108,328...35,154,578
Ensembl chr14:35,108,338...35,154,863
|
|
| G
|
Cx3cl1
|
C-X3-C motif chemokine ligand 1
|
multiple interactions decreases expression
|
ISO
|
CX3CL1 protein promotes the reaction [CGB3 protein results in increased abundance of Progesterone] Progesterone results in decreased expression of CX3CL1 mRNA
|
CTD |
PMID:18292196 PMID:22238285 |
|
NCBI chr19:10,233,326...10,244,856
Ensembl chr19:10,233,329...10,242,999
|
|
| G
|
Cxcl1
|
C-X-C motif chemokine ligand 1
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of CXCL1 mRNA; Progesterone results in decreased expression of CXCL1 protein
|
CTD |
PMID:22615136 |
|
NCBI chr14:17,477,542...17,479,321
Ensembl chr14:17,477,549...17,479,811
|
|
| G
|
Cxcl10
|
C-X-C motif chemokine ligand 10
|
multiple interactions decreases expression increases expression
|
ISO
|
[Progesterone co-treated with Estradiol] results in increased expression of CXCL10 mRNA Progesterone results in decreased expression of CXCL10 mRNA; Progesterone results in decreased expression of CXCL10 protein Progesterone results in increased expression of CXCL10 mRNA
|
CTD |
PMID:15557169 PMID:17404688 PMID:21549006 |
|
NCBI chr14:15,989,066...15,991,263
Ensembl chr14:15,989,018...15,991,261
|
|
| G
|
Cxcl11
|
C-X-C motif chemokine ligand 11
|
multiple interactions increases expression
|
ISO
|
[Progesterone co-treated with Estradiol] results in increased expression of CXCL11 mRNA Progesterone results in increased expression of CXCL11 mRNA
|
CTD |
PMID:15557169 PMID:17404688 |
|
NCBI chr14:15,973,728...15,976,503
Ensembl chr14:15,973,720...15,976,567
|
|
| G
|
Cxcl12
|
C-X-C motif chemokine ligand 12
|
multiple interactions increases expression decreases expression
|
ISO EXP
|
[Estradiol co-treated with Progesterone] results in decreased expression of CXCL12 mRNA Progesterone results in increased expression of CXCL12 mRNA [Estradiol co-treated with Progesterone] results in increased expression of CXCL12 mRNA Progesterone results in decreased expression of CXCL12 mRNA
|
CTD |
PMID:18556351 PMID:20660070 PMID:20726854 PMID:21795739 PMID:22238285 |
|
NCBI chr 4:152,060,781...152,073,628
Ensembl chr 4:152,060,780...152,073,627
|
|
| G
|
Cxcl14
|
C-X-C motif chemokine ligand 14
|
affects expression increases expression multiple interactions
|
ISO
|
Progesterone affects the expression of CXCL14 mRNA Progesterone results in increased expression of CXCL14 mRNA [Estradiol co-treated with Progesterone] results in decreased expression of CXCL14 mRNA; [Progesterone co-treated with Estradiol] results in decreased expression of CXCL14 mRNA; Progesterone promotes the reaction [PGR protein results in increased expression of CXCL14 mRNA]
|
CTD |
PMID:17251523 PMID:17404688 PMID:19903701 PMID:20660070 |
|
NCBI chr17:8,323,150...8,331,176
Ensembl chr17:8,323,143...8,331,172
|
|
| G
|
Cxcl17
|
C-X-C motif chemokine ligand 17
|
increases expression
|
ISO
|
Progesterone results in increased expression of CXCL17 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 1:90,112,561...90,124,648
Ensembl chr 1:90,112,771...90,124,535
|
|
| G
|
Cxcl2
|
C-X-C motif chemokine ligand 2
|
decreases expression multiple interactions increases expression
|
ISO
|
Progesterone results in decreased expression of CXCL2 mRNA; Progesterone results in decreased expression of CXCL2 protein [Progesterone co-treated with 1-Naphthylisothiocyanate] results in increased expression of CXCL2 mRNA; [Progesterone co-treated with Dicloxacillin] results in increased expression of CXCL2 mRNA; [Progesterone co-treated with Halothane] results in increased expression of CXCL2 mRNA; [Progesterone co-treated with Halothane] results in increased expression of CXCL2 protein; gadolinium chloride inhibits the reaction [[Progesterone co-treated with Halothane] results in increased expression of CXCL2 mRNA]; Mifepristone inhibits the reaction [Progesterone promotes the reaction [Halothane results in increased expression of CXCL2 mRNA]]; Progesterone promotes the reaction [Halothane results in increased expression of CXCL2 mRNA]; Progesterone promotes the reaction [Thioacetamide results in increased expression of CXCL2 mRNA]; U 0126 inhibits the reaction [[Progesterone co-treated with Halothane] results in increased expression of CXCL2 mRNA] Progesterone results in increased expression of CXCL2 mRNA
|
CTD |
PMID:21501669 PMID:21795739 PMID:22157104 PMID:22615136 |
|
NCBI chr14:17,465,210...17,467,255
Ensembl chr14:17,465,242...17,467,255
|
|
| G
|
Cxcl3
|
C-X-C motif chemokine ligand 3
|
decreases expression increases expression multiple interactions affects expression
|
ISO
|
Progesterone results in decreased expression of CXCL1 mRNA; Progesterone results in decreased expression of CXCL1 protein Progesterone results in increased expression of CXCL1 mRNA; Progesterone results in increased expression of CXCL1 protein gadolinium chloride inhibits the reaction [Progesterone promotes the reaction [Halothane results in increased expression of CXCL1 mRNA]]; gadolinium chloride inhibits the reaction [Progesterone results in increased expression of CXCL1 mRNA]; Mifepristone inhibits the reaction [Progesterone promotes the reaction [Halothane results in increased expression of CXCL1 mRNA]]; Mifepristone inhibits the reaction [Progesterone results in increased expression of CXCL1 mRNA]; Progesterone promotes the reaction [1-Naphthylisothiocyanate results in increased expression of CXCL1 mRNA]; Progesterone promotes the reaction [Dicloxacillin results in increased expression of CXCL1 mRNA]; Progesterone promotes the reaction [Halothane results in increased expression of CXCL1 mRNA]; Progesterone promotes the reaction [Thioacetamide results in increased expression of CXCL1 mRNA]; U 0126 inhibits the reaction [Progesterone promotes the reaction [Halothane results in increased expression of CXCL1 mRNA]]; U 0126 inhibits the reaction [Progesterone results in increased expression of CXCL1 mRNA] Progesterone affects the expression of CXCL1 mRNA
|
CTD |
PMID:17251523 PMID:21501669 PMID:22157104 PMID:22615136 |
|
NCBI chr14:17,571,900...17,573,624
Ensembl chr14:17,571,900...17,573,624
|
|
| G
|
Cxcl6
|
C-X-C motif chemokine ligand 6
|
affects expression
|
ISO
|
Progesterone affects the expression of CXCL5 mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr14:17,594,959...17,596,417
Ensembl chr14:17,594,959...17,596,417
|
|
| G
|
Cxcl9
|
C-X-C motif chemokine ligand 9
|
multiple interactions increases expression
|
ISO
|
[Progesterone co-treated with Estradiol] results in increased expression of CXCL9 mRNA Progesterone results in increased expression of CXCL9 mRNA
|
CTD |
PMID:18692832 |
|
NCBI chr14:15,722,868...15,727,779
Ensembl chr14:16,007,204...16,014,299
|
|
| G
|
Cxcr4
|
C-X-C motif chemokine receptor 4
|
decreases expression multiple interactions
|
EXP ISO
|
Progesterone results in decreased expression of CXCR4 mRNA [Estradiol co-treated with Progesterone] results in decreased expression of CXCR4 mRNA
|
CTD |
PMID:20660070 PMID:20726854 |
|
NCBI chr13:42,630,383...42,634,288
Ensembl chr13:42,630,104...42,634,459
|
|
| G
|
Cxxc5
|
CXXC finger protein 5
|
affects expression
|
ISO
|
Progesterone affects the expression of CXXC5 mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr18:27,427,591...27,458,579
Ensembl chr18:27,701,188...27,732,635
|
|
| G
|
Cyb5a
|
cytochrome b5 type A
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of CYB5A mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr18:80,487,923...80,520,544
Ensembl chr18:14,453,966...14,455,094 Ensembl chr18:14,453,966...14,455,094
|
|
| G
|
Cyb5b
|
cytochrome b5 type B
|
increases expression
|
ISO
|
Progesterone results in increased expression of CYB5B mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr19:35,062,871...35,096,741
Ensembl chr19:51,972,547...52,026,980
|
|
| G
|
Cyba
|
cytochrome b-245 alpha chain
|
increases expression
|
ISO
|
Progesterone results in increased expression of CYBA mRNA
|
CTD |
PMID:16195479 |
|
NCBI chr19:50,487,598...50,495,669
Ensembl chr19:67,396,143...67,404,214
|
|
| G
|
Cycs
|
cytochrome c, somatic
|
multiple interactions
|
EXP
|
[Progesterone co-treated with Estradiol] results in increased expression of CYCS mRNA
|
CTD |
PMID:18829022 |
|
NCBI chr 4:80,982,667...80,984,767
Ensembl chr 4:80,982,668...80,984,816 Ensembl chr18:80,982,668...80,984,816
|
|
| G
|
Cyfip2
|
cytoplasmic FMR1 interacting protein 2
|
multiple interactions decreases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of CYFIP2 mRNA Progesterone results in decreased expression of CYFIP2 mRNA
|
CTD |
PMID:20660070 PMID:20864642 |
|
NCBI chr10:31,122,653...31,242,440
Ensembl chr10:31,122,653...31,242,440
|
|
| G
|
Cyp11a1
|
cytochrome P450, family 11, subfamily a, polypeptide 1
|
affects abundance increases chemical synthesis multiple interactions affects chemical synthesis
|
ISO EXP
|
CYP11A1 protein affects the abundance of Progesterone CYP11A1 protein results in increased chemical synthesis of Progesterone CYP11A1 mRNA affects the abundance of Progesterone [2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane results in decreased activity of CYP11A1 protein] which results in decreased chemical synthesis of Progesterone; [bisphenol A affects the expression of CYP11A1 mRNA] which affects the abundance of Progesterone; [Diethylstilbestrol results in decreased expression of CYP11A1 protein] which results in decreased abundance of Progesterone; [FSHB protein results in increased expression of CYP11A1 mRNA] which results in increased abundance of Progesterone; GH1 protein promotes the reaction [[FSHB protein results in increased expression of CYP11A1 mRNA] which results in increased abundance of Progesterone]; IGF1 protein promotes the reaction [[FSHB protein results in increased expression of CYP11A1 mRNA] which results in increased abundance of Progesterone]; manganese chloride inhibits the reaction [CYP11A1 protein results in increased chemical synthesis of Progesterone] CYP11A1 protein affects the chemical synthesis of Progesterone
|
CTD |
PMID:10964264 PMID:11502818 PMID:12699903 PMID:15819722 PMID:18191889 PMID:21664964 PMID:22067323 PMID:23873838 More...
|
|
NCBI chr 8:67,318,665...67,330,196
Ensembl chr 8:67,270,556...67,330,196
|
|
| G
|
Cyp17a1
|
cytochrome P450, family 17, subfamily a, polypeptide 1
|
multiple interactions increases hydroxylation affects metabolic processing
|
ISO EXP
|
[[abiraterone results in decreased activity of CYP17A1 protein] which results in decreased hydroxylation of Progesterone] which results in increased chemical synthesis of 17-alpha-Hydroxyprogesterone; [abiraterone results in decreased activity of CYP17A1 protein] which results in decreased hydroxylation of Progesterone; [CYP17A1 protein results in increased hydroxylation of Progesterone] which results in increased chemical synthesis of 16-hydroxyprogesterone; [CYP17A1 protein results in increased hydroxylation of Progesterone] which results in increased chemical synthesis of 17-alpha-Hydroxyprogesterone; CYP17A1 protein binds to and affects the metabolism of Progesterone; Duloxetine Hydrochloride inhibits the reaction [[CYP17A1 protein results in increased hydroxylation of Progesterone] which results in increased chemical synthesis of 17-alpha-Hydroxyprogesterone]; Duloxetine Hydrochloride inhibits the reaction [CYP17A1 protein results in increased hydroxylation of Progesterone]; Venlafaxine Hydrochloride inhibits the reaction [[CYP17A1 protein results in increased hydroxylation of Progesterone] which results in increased chemical synthesis of 17-alpha-Hydroxyprogesterone]; Venlafaxine Hydrochloride inhibits the reaction [CYP17A1 protein results in increased hydroxylation of Progesterone] [[3,4',5-trimethoxystilbene co-treated with CGA protein] results in decreased expression of CYP17A1 protein] which results in increased secretion of Progesterone; [[resveratrol analog co-treated with CGA protein] results in decreased expression of CYP17A1 protein] which results in increased secretion of Progesterone; [[resveratrol co-treated with CGA protein] results in decreased expression of CYP17A1 protein] which results in increased secretion of Progesterone CYP17A1 protein affects the metabolism of Progesterone
|
CTD |
PMID:14522586 PMID:15261307 PMID:15562394 PMID:16030167 PMID:16054388 PMID:17194026 PMID:19603415 PMID:29100959 More...
|
|
NCBI chr 1:255,476,861...255,484,547
Ensembl chr 1:255,476,861...255,482,974
|
|
| G
|
Cyp19a1
|
cytochrome P450, family 19, subfamily a, polypeptide 1
|
increases activity multiple interactions decreases expression
|
ISO EXP
|
Progesterone results in increased activity of CYP19A1 protein [FSHB protein results in increased expression of CYP19A1 mRNA] which results in increased abundance of Progesterone; IGF1 protein promotes the reaction [[FSHB protein results in increased expression of CYP19A1 mRNA] which results in increased abundance of Progesterone] Progesterone results in decreased expression of CYP19A1 mRNA
|
CTD |
PMID:15862960 PMID:22067323 PMID:22130322 |
|
NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:63,449,148...63,476,917
|
|
| G
|
Cyp1a1
|
cytochrome P450, family 1, subfamily a, polypeptide 1
|
increases hydroxylation decreases activity decreases expression multiple interactions
|
ISO EXP
|
CYP1A1 protein results in increased hydroxylation of Progesterone Progesterone results in decreased activity of CYP1A1 protein Progesterone results in decreased expression of CYP1A1 mRNA Progesterone inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein] [Estradiol co-treated with Progesterone co-treated with Hydrocortisone co-treated with PRL protein] inhibits the reaction [benz(a)anthracene results in increased expression of CYP1A1 protein]; [Estradiol co-treated with Progesterone] affects the expression of CYP1A1 mRNA; Progesterone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]
|
CTD |
PMID:8674863 PMID:10975606 PMID:11281733 PMID:24777823 PMID:32668270 PMID:34181028 More...
|
|
NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012
|
|
| G
|
Cyp1b1
|
cytochrome P450, family 1, subfamily b, polypeptide 1
|
decreases expression decreases activity increases expression multiple interactions
|
ISO EXP
|
Progesterone results in decreased expression of CYP1B1 mRNA Progesterone results in decreased activity of CYP1B1 protein Progesterone results in increased expression of CYP1B1 mRNA [Estradiol co-treated with Progesterone] results in increased expression of CYP1B1 mRNA; Progesterone promotes the reaction [laquinimod metabolite results in increased expression of CYP1B1 mRNA] Progesterone results in decreased expression of CYP1B1 protein [Estradiol co-treated with Progesterone co-treated with Hydrocortisone co-treated with PRL protein] inhibits the reaction [benz(a)anthracene results in increased expression of CYP1B1 protein]; Progesterone inhibits the reaction [benz(a)anthracene results in increased expression of CYP1B1 protein]; Progesterone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]
|
CTD |
PMID:8674863 PMID:18037150 PMID:20660070 PMID:20726854 PMID:32668270 PMID:33814510 More...
|
|
NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:21,078,146...21,103,142
|
|
| G
|
Cyp24a1
|
cytochrome P450, family 24, subfamily a, polypeptide 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of CYP24A1 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 3:179,694,647...179,709,083
Ensembl chr 3:179,694,647...179,709,083
|
|
| G
|
Cyp26a1
|
cytochrome P450, family 26, subfamily a, polypeptide 1
|
multiple interactions affects expression increases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of CYP26A1 mRNA; [Progesterone co-treated with Estradiol] results in increased expression of CYP26A1 mRNA Progesterone affects the expression of CYP26A1 mRNA [Progesterone results in increased activity of PGR protein] which results in increased expression of CYP26A1 mRNA Progesterone results in increased expression of CYP26A1 mRNA
|
CTD |
PMID:15845616 PMID:17251523 PMID:17404688 PMID:20660070 |
|
NCBI chr 1:244,883,822...244,887,657
Ensembl chr 1:244,883,752...244,887,657
|
|
| G
|
Cyp27a1
|
cytochrome P450, family 27, subfamily a, polypeptide 1
|
multiple interactions increases expression
|
ISO
|
CYP27A1 protein affects the metabolism of and affects the abundance of Progesterone Progesterone results in increased expression of CYP27A1 mRNA
|
CTD |
PMID:19671838 PMID:22238285 |
|
NCBI chr 9:83,712,402...83,743,222
Ensembl chr 9:83,713,293...83,743,215
|
|
| G
|
Cyp27b1
|
cytochrome P450, family 27, subfamily b, polypeptide 1
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of CYP27B1 mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr 7:64,756,626...64,761,570
Ensembl chr 7:64,756,626...64,761,570
|
|
| G
|
Cyp2b3
|
cytochrome P450, family 2, subfamily b, polypeptide 3
|
multiple interactions increases expression decreases expression
|
ISO
|
[Progesterone co-treated with Estradiol] inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of CYP2B6 mRNA]; [Progesterone co-treated with Estradiol] inhibits the reaction [Phenobarbital results in increased expression of CYP2B6 mRNA]; NR1I3 mutant form inhibits the reaction [Progesterone inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of CYP2B6 mRNA]]; NR1I3 mutant form inhibits the reaction [Progesterone inhibits the reaction [Phenobarbital results in increased expression of CYP2B6 mRNA]]; Progesterone inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of CYP2B6 mRNA]; Progesterone inhibits the reaction [Phenobarbital results in increased expression of CYP2B6 mRNA] Progesterone results in increased expression of CYP2B10 mRNA Progesterone results in decreased expression of CYP2B10 mRNA Progesterone results in increased expression of CYP2B6 mRNA
|
CTD |
PMID:7771797 PMID:11075820 PMID:21768169 PMID:22837389 |
|
NCBI chr 1:90,780,468...90,859,852
|
|
| G
|
Cyp2c11
|
cytochrome P450, subfamily 2, polypeptide 11
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of CYP2C18 mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr 1:246,175,216...246,211,445
Ensembl chr 1:246,174,711...246,211,853
|
|
| G
|
Cyp2c6
|
cytochrome P450, family 2, subfamily C, polypeptide 6
|
increases hydroxylation
|
ISO
|
CYP2C19 protein results in increased hydroxylation of Progesterone
|
CTD |
PMID:18957504 |
|
NCBI chr 1:247,879,058...247,916,804
Ensembl chr 1:247,879,078...247,916,798
|
|
| G
|
Cyp2c79
|
cytochrome P450, family 2, subfamily c, polypeptide 79
|
increases expression
|
ISO
|
Progesterone results in increased expression of CYP2C8 mRNA
|
CTD |
PMID:22837389 |
|
|
|
| G
|
Cyp2e1
|
cytochrome P450, family 2, subfamily e, polypeptide 1
|
affects expression multiple interactions
|
ISO EXP
|
Progesterone affects the expression of CYP2E1 mRNA Progesterone promotes the reaction [Benzene results in decreased activity of CYP2E1 protein]
|
CTD |
PMID:17251523 PMID:18407866 |
|
NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:205,267,505...205,293,495
|
|
| G
|
Cyp2g1
|
cytochrome P450, family 2, subfamily g, polypeptide 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of CYP2G1 mRNA
|
CTD |
PMID:19693291 |
|
NCBI chr 1:91,273,309...91,284,499
Ensembl chr 1:91,272,680...91,284,498
|
|
| G
|
Cyp3a2
|
cytochrome P450, family 3, subfamily a, polypeptide 2
|
increases expression increases hydroxylation multiple interactions
|
ISO
|
Progesterone results in increased expression of CYP3A4 mRNA CYP3A4 protein results in increased hydroxylation of Progesterone Progesterone promotes the reaction [CYP3A4 protein results in increased oxidation of 7-benzyloxy-4-trifluoromethylcoumarin]
|
CTD |
PMID:18957504 PMID:19299527 PMID:22837389 |
|
NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857
|
|
| G
|
Cyp3a23-3a1
|
cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1
|
increases expression
|
EXP
|
Progesterone results in increased expression of CYP3A23-3A1 mRNA
|
CTD |
PMID:10707959 |
|
NCBI chr12:14,369,950...14,398,803
Ensembl chr12:14,368,266...14,398,813
|
|
| G
|
Cyp3a9
|
cytochrome P450, family 3, subfamily a, polypeptide 9
|
increases expression
|
ISO
|
Progesterone results in increased expression of CYP3A5 mRNA
|
CTD |
PMID:22837389 |
|
NCBI chr12:21,919,955...21,960,160
Ensembl chr12:21,919,940...21,960,154
|
|
| G
|
Cyp46a1
|
cytochrome P450, family 46, subfamily a, polypeptide 1
|
increases hydroxylation
|
ISO
|
CYP46A1 protein results in increased hydroxylation of Progesterone
|
CTD |
PMID:14640697 |
|
NCBI chr 6:133,011,948...133,039,167
Ensembl chr 6:133,011,989...133,041,971
|
|
| G
|
Cyp4b1
|
cytochrome P450, family 4, subfamily b, polypeptide 1
|
multiple interactions increases expression
|
ISO
|
[Progesterone co-treated with Estradiol] results in increased expression of CYP4B1 mRNA Progesterone results in increased expression of CYP4B1 mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr 5:134,375,807...134,413,635
Ensembl chr 5:134,375,807...134,393,116
|
|
| G
|
Cyp51
|
cytochrome P450, family 51
|
increases expression
|
ISO
|
Progesterone results in increased expression of CYP51A1 mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr 4:30,991,693...31,010,147
Ensembl chr 4:30,991,613...31,010,450
|
|
| G
|
Dab1
|
DAB adaptor protein 1
|
increases expression
|
ISO
|
Progesterone results in increased expression of DAB1 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 5:118,392,953...119,513,625
Ensembl chr 5:124,369,415...124,742,584
|
|
| G
|
Dach1
|
dachshund family transcription factor 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of DACH1 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr15:80,936,063...81,317,746
Ensembl chr15:80,936,063...81,317,627
|
|
| G
|
Dact1
|
dishevelled-binding antagonist of beta-catenin 1
|
decreases expression multiple interactions
|
ISO
|
Progesterone results in decreased expression of DACT1 mRNA [Estradiol co-treated with Progesterone] results in decreased expression of DACT1 mRNA; [Progesterone co-treated with Estradiol] results in decreased expression of DACT1 mRNA
|
CTD |
PMID:17404688 PMID:20660070 |
|
NCBI chr 6:95,526,645...95,538,625
Ensembl chr 6:95,526,690...95,551,053
|
|
| G
|
Dap3
|
death associated protein 3
|
affects expression
|
ISO
|
Progesterone affects the expression of DAP3 mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr 2:174,319,341...174,347,489
Ensembl chr 2:176,617,155...176,644,270
|
|
| G
|
Dbi
|
diazepam binding inhibitor
|
affects expression
|
ISO
|
Progesterone affects the expression of DBI mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr13:33,794,231...33,802,632
Ensembl chr13:33,759,845...33,821,450
|
|
| G
|
Dbn1
|
drebrin 1
|
multiple interactions decreases expression
|
ISO EXP
|
[Progesterone co-treated with Estradiol] results in decreased expression of DBN1 mRNA Progesterone results in decreased expression of DBN1 mRNA
|
CTD |
PMID:17404688 PMID:20726854 |
|
NCBI chr17:9,150,608...9,164,982
Ensembl chr17:9,155,787...9,170,122
|
|
| G
|
Dbndd2
|
dysbindin domain containing 2
|
increases expression
|
ISO
|
Progesterone results in increased expression of DBNDD2 mRNA
|
CTD |
PMID:21795739 |
|
NCBI chr 3:153,216,300...153,220,651
|
|
| G
|
Dbnl
|
drebrin-like
|
affects expression
|
ISO
|
Progesterone affects the expression of DBNL mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr14:80,666,115...80,681,155
Ensembl chr14:84,880,142...84,897,133
|
|
| G
|
Dbp
|
D-box binding PAR bZIP transcription factor
|
affects expression decreases expression
|
ISO EXP
|
Progesterone affects the expression of DBP mRNA Progesterone results in decreased expression of DBP mRNA
|
CTD |
PMID:17251523 PMID:20726854 |
|
NCBI chr 1:105,312,256...105,317,205
Ensembl chr 1:105,312,108...105,317,205
|
|
| G
|
Dcaf12
|
DDB1 and CUL4 associated factor 12
|
affects expression
|
ISO
|
Progesterone affects the expression of DCAF12 mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr 5:61,256,353...61,278,155
Ensembl chr 5:61,256,353...61,278,119
|
|
| G
|
Dcbld2
|
discoidin, CUB and LCCL domain containing 2
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of DCBLD2 mRNA
|
CTD |
PMID:21795739 |
|
NCBI chr11:55,594,691...55,649,113
Ensembl chr11:55,594,691...55,649,085
|
|
| G
|
Dchs1
|
dachsous cadherin-related 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of DCHS1 mRNA; [Progesterone co-treated with Estradiol] results in decreased expression of DCHS1 mRNA
|
CTD |
PMID:17404688 PMID:20660070 |
|
NCBI chr 1:160,104,931...160,138,958
Ensembl chr 1:169,516,762...169,536,639
|
|
| G
|
Dclk1
|
doublecortin-like kinase 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of DCLK1 mRNA
|
CTD |
PMID:19693291 |
|
NCBI chr 2:141,567,215...141,861,088
Ensembl chr 2:141,571,983...141,861,090
|
|
| G
|
Dcxr
|
dicarbonyl and L-xylulose reductase
|
increases expression
|
EXP
|
Progesterone results in increased expression of DCXR mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr10:106,504,730...106,506,619
|
|
| G
|
Ddah1
|
dimethylarginine dimethylaminohydrolase 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of DDAH1 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 2:237,327,812...237,460,624
Ensembl chr 2:237,327,766...237,460,626
|
|
| G
|
Ddah2
|
DDAH family member 2, ADMA-independent
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of DDAH2 mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr20:3,761,460...3,764,718
Ensembl chr20:3,766,120...3,769,183
|
|
| G
|
Ddit3
|
DNA-damage inducible transcript 3
|
increases expression
|
ISO
|
Progesterone results in increased expression of DDIT3 mRNA; Progesterone results in increased expression of DDIT3 protein
|
CTD |
PMID:18037150 PMID:21525004 |
|
NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:65,005,501...65,006,509
|
|
| G
|
Ddit4
|
DNA-damage-inducible transcript 4
|
increases expression
|
ISO
|
Progesterone results in increased expression of DDIT4 mRNA
|
CTD |
PMID:18037150 PMID:21795739 |
|
NCBI chr20:28,434,938...28,437,037
Ensembl chr20:28,434,944...28,437,037
|
|
| G
|
Ddt
|
D-dopachrome tautomerase
|
increases expression
|
EXP
|
Progesterone results in increased expression of DDT mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr20:12,883,025...12,886,121
|
|
| G
|
Ddx21
|
DExD-box helicase 21
|
affects expression
|
ISO
|
Progesterone affects the expression of DDX21 mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr20:30,534,319...30,554,513
Ensembl chr20:31,077,045...31,097,238
|
|
| G
|
Ddx39a
|
DExD-box helicase 39A
|
decreases expression
|
EXP
|
Progesterone results in decreased expression of DDX39A mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr19:41,323,465...41,331,413
Ensembl chr19:41,322,836...41,332,306
|
|
| G
|
Ddx43
|
DEAD-box helicase 43
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of DDX43 mRNA
|
CTD |
PMID:21540246 |
|
NCBI chr 8:88,135,255...88,172,872
Ensembl chr 8:88,135,882...88,164,749
|
|
| G
|
Ddx6
|
DEAD-box helicase 6
|
affects expression
|
ISO
|
Progesterone affects the expression of DDX6 mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr 8:53,827,661...53,864,538
Ensembl chr 8:53,827,835...53,860,977
|
|
| G
|
Defb1
|
defensin beta 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of DEFB1 mRNA [Progesterone co-treated with bazedoxifene] results in increased expression of DEFB1 mRNA; [Progesterone co-treated with Estradiol] results in increased expression of DEFB1 mRNA; [Progesterone co-treated with Lasofoxifene] results in increased expression of DEFB1 mRNA; [Progesterone co-treated with Raloxifene Hydrochloride] results in increased expression of DEFB1 mRNA
|
CTD |
PMID:18367319 PMID:20660070 |
|
NCBI chr16:77,001,326...77,016,068
Ensembl chr16:77,001,326...77,016,068
|
|
| G
|
Defb5
|
defensin beta 5
|
multiple interactions increases expression
|
ISO
|
Lipopolysaccharides inhibits the reaction [Progesterone results in increased expression of DEFB4A mRNA]
|
CTD |
PMID:19819163 |
|
NCBI chr16:70,612,985...70,615,389
Ensembl chr16:77,315,424...77,317,828
|
|
| G
|
Dek
|
DEK proto-oncogene
|
increases expression
|
ISO
|
Progesterone results in increased expression of DEK protein
|
CTD |
PMID:23071688 |
|
NCBI chr17:17,786,989...17,809,096
Ensembl chr17:17,787,139...17,810,122
|
|
| G
|
Dennd1c
|
DENN domain containing 1C
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of DENND1C mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 9:1,904,040...1,916,329
Ensembl chr 9:1,991,039...2,003,151
|
|
| G
|
Dennd2a
|
DENN domain containing 2A
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of DENND2A mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr 4:69,199,814...69,299,128
Ensembl chr 4:69,199,814...69,298,984
|
|
| G
|
Dennd2d
|
DENN domain containing 2D
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of DENND2D mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 2:193,973,231...193,992,275
Ensembl chr 2:196,661,345...196,682,397
|
|
| G
|
Depdc1
|
DEP domain containing 1
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of DEPDC1 mRNA
|
CTD |
PMID:21795739 |
|
NCBI chr 2:251,343,250...251,376,709
Ensembl chr 2:251,343,281...251,376,709
|
|
| G
|
Depdc1b
|
DEP domain containing 1B
|
increases expression
|
ISO
|
Progesterone results in increased expression of DEPDC1B mRNA
|
CTD |
PMID:21540246 |
|
NCBI chr 2:41,605,686...41,697,207
Ensembl chr 2:41,624,922...41,697,202
|
|
| G
|
Depp1
|
DEPP autophagy regulator 1
|
multiple interactions increases expression
|
ISO
|
Mifepristone inhibits the reaction [Progesterone results in increased expression of DEPP1 mRNA]
|
CTD |
PMID:16123073 PMID:18070364 PMID:20864642 |
|
NCBI chr 4:149,910,794...149,913,013
Ensembl chr 4:151,581,502...151,586,233
|
|
| G
|
Deptor
|
DEP domain containing MTOR-interacting protein
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of DEPTOR mRNA
|
CTD |
PMID:23541542 |
|
NCBI chr 7:88,404,745...88,574,065
Ensembl chr 7:88,404,620...88,574,041
|
|
| G
|
Des
|
desmin
|
decreases expression multiple interactions increases expression
|
ISO EXP
|
Progesterone results in decreased expression of DES mRNA [Progesterone co-treated with Estradiol] results in decreased expression of DES mRNA Progesterone results in increased expression of DES mRNA [Estradiol co-treated with Progesterone] results in increased expression of DES mRNA
|
CTD |
PMID:18070364 PMID:18692832 PMID:19089455 PMID:20726854 |
|
NCBI chr 9:76,850,979...76,858,695
Ensembl chr 9:84,298,447...84,307,347
|
|
| G
|
Dgkb
|
diacylglycerol kinase, beta
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of DGKB mRNA
|
CTD |
PMID:21795739 |
|
NCBI chr 6:60,368,101...61,124,420
Ensembl chr 6:60,368,519...61,124,420
|
|
| G
|
Dgkd
|
diacylglycerol kinase, delta
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of DGKD mRNA
|
CTD |
PMID:21540246 |
|
NCBI chr 9:88,516,686...88,607,349
Ensembl chr 9:95,964,148...96,055,160
|
|
| G
|
Dhcr7
|
7-dehydrocholesterol reductase
|
increases expression
|
ISO
|
Progesterone results in increased expression of DHCR7 mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr 1:208,444,434...208,460,408
Ensembl chr 1:208,444,434...208,461,382
|
|
| G
|
Dhrs3
|
dehydrogenase/reductase 3
|
multiple interactions increases expression
|
ISO
|
7-propyl spirolactone inhibits the reaction [[Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of DHRS3 protein]; [Estradiol co-treated with Progesterone] results in decreased expression of DHRS3 mRNA; [Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with Estradiol] results in increased expression of DHRS3 mRNA; [Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of DHRS3 protein; Aldosterone promotes the reaction [[Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of DHRS3 protein]; Mifepristone promotes the reaction [Progesterone affects the expression of DHRS3 mRNA]; NR3C2 protein promotes the reaction [[Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with Estradiol] results in increased expression of DHRS3 mRNA] Progesterone results in increased expression of DHRS3 mRNA
|
CTD |
PMID:20660070 PMID:21540246 PMID:22414680 PMID:23275455 |
|
NCBI chr 5:162,031,853...162,065,655
Ensembl chr 5:162,031,386...162,065,653
|
|
| G
|
Dhx15
|
DEAH-box helicase 15
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of DHX15 mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr14:62,999,886...63,037,829
Ensembl chr14:62,999,877...63,037,828
|
|
| G
|
Diaph1
|
diaphanous-related formin 1
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of DIAPH1 mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr18:29,920,889...30,020,280
Ensembl chr18:29,920,889...30,020,280
|
|
| G
|
Diaph2
|
diaphanous-related formin 2
|
increases expression
|
ISO
|
Progesterone results in increased expression of DIAPH2 mRNA
|
CTD |
PMID:20864642 |
|
NCBI chr X:92,395,189...93,234,521
Ensembl chr X:96,700,726...97,528,080
|
|
| G
|
Diaph3
|
diaphanous-related formin 3
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of DIAPH3 mRNA
|
CTD |
PMID:21795739 |
|
NCBI chr15:62,543,375...63,013,060
Ensembl chr15:68,951,989...69,421,552
|
|
| G
|
Dicer1
|
dicer 1 ribonuclease III
|
increases expression
|
ISO
|
Progesterone results in increased expression of DICER1 mRNA
|
CTD |
PMID:20852728 |
|
NCBI chr 6:129,392,298...129,457,252
Ensembl chr 6:129,396,014...129,457,252
|
|
| G
|
Dio2
|
iodothyronine deiodinase 2
|
multiple interactions decreases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of DIO2 mRNA; [Progesterone co-treated with Estradiol] results in decreased expression of DIO2 mRNA Progesterone results in decreased expression of DIO2 mRNA
|
CTD |
PMID:17404688 PMID:20660070 |
|
NCBI chr 6:109,665,523...109,679,809
Ensembl chr 6:115,396,308...115,410,594
|
|
| G
|
Dkk1
|
dickkopf WNT signaling pathway inhibitor 1
|
multiple interactions increases expression affects response to substance
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of DKK1 mRNA; [Progesterone co-treated with Estradiol] results in increased expression of DKK1 mRNA; Mifepristone inhibits the reaction [Progesterone results in increased expression of DKK1 mRNA]; Mifepristone inhibits the reaction [Progesterone results in increased expression of DKK1 protein] Progesterone results in increased expression of DKK1 mRNA; Progesterone results in increased expression of DKK1 protein DKK1 protein affects the susceptibility to Progesterone
|
CTD |
PMID:16449346 PMID:17404688 PMID:20660070 PMID:20864642 PMID:21546446 PMID:21795739 More...
|
|
NCBI chr 1:228,381,521...228,385,202
Ensembl chr 1:237,794,969...237,798,650
|
|
| G
|
Dkk3
|
dickkopf WNT signaling pathway inhibitor 3
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of DKK3 mRNA
|
CTD |
PMID:21273126 |
|
NCBI chr 1:175,672,834...175,715,867
Ensembl chr 1:175,672,834...175,715,186
|
|
| G
|
Dlc1
|
DLC1 Rho GTPase activating protein
|
multiple interactions increases expression
|
ISO
|
Mifepristone inhibits the reaction [Progesterone results in increased expression of DLC1 mRNA]
|
CTD |
PMID:15674352 |
|
NCBI chr16:61,954,177...62,374,819
Ensembl chr16:61,995,001...62,374,819
|
|
| G
|
Dld
|
dihydrolipoamide dehydrogenase
|
increases abundance
|
EXP
|
DLD protein results in increased abundance of Progesterone
|
CTD |
PMID:25981801 |
|
NCBI chr 6:53,631,686...53,655,059
Ensembl chr 6:53,619,631...53,652,354
|
|
| G
|
Dleu7
|
deleted in lymphocytic leukemia, 7
|
increases expression
|
ISO
|
Progesterone results in increased expression of DLEU7 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr15:40,655,563...40,671,759
Ensembl chr15:40,655,563...40,671,759
|
|
| G
|
Dlg5
|
discs large MAGUK scaffold protein 5
|
multiple interactions increases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of DLG5 mRNA Progesterone results in increased expression of DLG5 mRNA
|
CTD |
PMID:18497975 PMID:20660070 |
|
NCBI chr15:75,786...209,735
Ensembl chr15:125,290...237,332
|
|
| G
|
Dlgap1
|
DLG associated protein 1
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of DLGAP1 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 9:117,304,144...118,173,463
Ensembl chr 9:117,614,061...118,173,463
|
|
| G
|
Dlgap5
|
DLG associated protein 5
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of DLGAP5 mRNA
|
CTD |
PMID:21795739 |
|
NCBI chr15:23,113,678...23,144,281
Ensembl chr15:23,113,678...23,144,176
|
|
| G
|
Dlx2
|
distal-less homeobox 2
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of DLX2 mRNA
|
CTD |
PMID:21795739 |
|
NCBI chr 3:76,777,912...76,781,255
Ensembl chr 3:76,777,912...76,781,255
|
|
| G
|
Dlx4
|
distal-less homeobox 4
|
increases expression
|
ISO
|
Progesterone results in increased expression of DLX4 mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr10:80,085,037...80,090,434
Ensembl chr10:80,582,303...80,587,294
|
|
| G
|
Dlx5
|
distal-less homeobox 5
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of DLX5 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 4:35,965,579...35,969,973
Ensembl chr 4:35,965,579...35,969,845
|
|
| G
|
Dmac2l
|
distal membrane arm assembly component 2 like
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of DMAC2L mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr 6:93,941,605...93,959,932
Ensembl chr 6:93,941,690...93,960,662
|
|
| G
|
Dmbt1
|
deleted in malignant brain tumors 1
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of DMBT1 mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr 1:185,617,469...185,696,476
Ensembl chr 1:195,047,713...195,126,704
|
|
| G
|
Dmd
|
dystrophin
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of DMD mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr X:47,272,324...49,504,219
Ensembl chr X:51,070,273...53,437,835
|
|
| G
|
Dmp1
|
dentin matrix acidic phosphoprotein 1
|
increases expression
|
ISO
|
Progesterone results in increased expression of DMP1 mRNA
|
CTD |
PMID:19000923 |
|
NCBI chr14:5,833,111...5,867,154
Ensembl chr14:5,833,111...5,843,993
|
|
| G
|
Dmpk
|
DM1 protein kinase
|
affects expression
|
ISO
|
Progesterone affects the expression of DMPK mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr 1:87,858,294...87,868,624
Ensembl chr 1:87,858,316...87,868,910
|
|
| G
|
Dnaaf2
|
dynein, axonemal, assembly factor 2
|
increases expression
|
ISO
|
Progesterone results in increased expression of DNAAF2 mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr 6:87,661,101...87,670,267
Ensembl chr 6:93,397,164...93,406,323
|
|
| G
|
Dnajb1
|
DnaJ heat shock protein family (Hsp40) member B1
|
increases expression
|
ISO
|
Progesterone results in increased expression of DNAJB1 mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr19:41,427,453...41,431,141
Ensembl chr19:41,427,453...41,431,416
|
|
| G
|
Dnajb11
|
DnaJ heat shock protein family (Hsp40) member B11
|
affects expression
|
ISO
|
Progesterone affects the expression of DNAJB11 mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr11:91,656,334...91,672,800
Ensembl chr11:91,656,335...91,672,800
|
|
| G
|
Dnajb9
|
DnaJ heat shock protein family (Hsp40) member B9
|
increases expression
|
ISO
|
Progesterone results in increased expression of DNAJB9 mRNA
|
CTD |
PMID:18037150 PMID:18070364 |
|
NCBI chr 6:66,997,842...67,007,371
Ensembl chr 6:66,997,842...67,009,344
|
|
| G
|
Dnajc15
|
DnaJ heat shock protein family (Hsp40) member C15
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of DNAJC15 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr15:53,182,060...53,249,675
Ensembl chr15:59,594,314...59,658,987
|
|
| G
|
Dnajc8
|
DnaJ heat shock protein family (Hsp40) member C8
|
affects expression
|
ISO
|
Progesterone affects the expression of DNAJC8 mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr 5:144,745,055...144,763,106
Ensembl chr 5:150,026,286...150,047,117
|
|
| G
|
Dnajc9
|
DnaJ heat shock protein family (Hsp40) member C9
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of DNAJC9 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr15:3,970,843...4,003,009
Ensembl chr15:3,970,114...3,977,304
|
|
| G
|
Dner
|
delta/notch-like EGF repeat containing
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of DNER mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 9:85,586,985...85,902,461
Ensembl chr 9:93,035,108...93,350,568
|
|
| G
|
Dnm3
|
dynamin 3
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of DNM3 mRNA
|
CTD |
PMID:21795739 |
|
NCBI chr13:74,359,043...74,838,135
Ensembl chr13:76,892,171...77,371,350
|
|
| G
|
Dnmbp
|
dynamin binding protein
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of DNMBP mRNA
|
CTD |
PMID:19693291 |
|
NCBI chr 1:242,736,189...242,829,431
Ensembl chr 1:252,685,406...252,778,688
|
|
| G
|
Dnttip1
|
deoxynucleotidyltransferase, terminal, interacting protein 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of DNTTIP1 mRNA
|
CTD |
PMID:18556351 |
|
NCBI chr 3:173,901,070...173,924,742
Ensembl chr 3:173,900,945...173,925,098
|
|
| G
|
Doc2b
|
double C2 domain beta
|
increases expression
|
ISO
|
Progesterone results in increased expression of DOC2B mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr10:61,126,295...61,151,533
Ensembl chr10:61,126,295...61,151,533
|
|
| G
|
Dock4
|
dedicator of cytokinesis 4
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of DOCK4 mRNA
|
CTD |
PMID:21795739 |
|
NCBI chr 6:63,240,050...63,629,772
Ensembl chr 6:63,240,136...63,629,772
|
|
| G
|
Dpep1
|
dipeptidase 1
|
increases expression
|
EXP
|
Progesterone results in increased expression of DPEP1 mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr19:68,118,270...68,143,781
Ensembl chr19:68,118,453...68,143,775
|
|
| G
|
Dpp4
|
dipeptidylpeptidase 4
|
multiple interactions increases expression
|
ISO
|
[Progesterone co-treated with Estradiol] results in increased expression of DPP4 mRNA Progesterone results in increased expression of DPP4 mRNA
|
CTD |
PMID:17404688 PMID:21540246 PMID:21795739 |
|
NCBI chr 3:67,370,794...67,452,422
Ensembl chr 3:67,370,804...67,452,422
|
|
| G
|
Dpp6
|
dipeptidyl peptidase like 6
|
increases expression
|
EXP
|
Progesterone results in increased expression of DPP6 mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr 4:7,589,386...8,508,666
Ensembl chr 4:8,324,843...9,242,209
|
|
| G
|
Dpp7
|
dipeptidylpeptidase 7
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of DPP7 mRNA
|
CTD |
PMID:18556351 |
|
NCBI chr 3:28,563,240...28,567,492
Ensembl chr 3:28,563,240...28,567,492
|
|
| G
|
Dpt
|
dermatopontin
|
increases expression
|
ISO
|
Progesterone results in increased expression of DPT mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr13:79,656,341...79,684,759
Ensembl chr13:79,655,985...79,684,758
|
|
| G
|
Drd4
|
dopamine receptor D4
|
increases expression
|
ISO
|
Progesterone results in increased expression of DRD4 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 1:205,825,937...205,829,124
Ensembl chr 1:205,826,049...205,830,458
|
|
| G
|
Dsp
|
desmoplakin
|
multiple interactions decreases expression
|
ISO
|
NCOA2 protein affects the reaction [Progesterone results in decreased expression of DSP mRNA]
|
CTD |
PMID:17556502 PMID:22238285 |
|
NCBI chr17:26,829,153...26,877,419
Ensembl chr17:26,829,153...26,877,121
|
|
| G
|
Dst
|
dystonin
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of DST mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr 9:43,631,716...44,025,535
Ensembl chr 9:43,631,517...44,025,533
|
|
| G
|
Dtl
|
denticleless E3 ubiquitin protein ligase homolog
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of DTL mRNA
|
CTD |
PMID:21795739 |
|
NCBI chr13:105,646,908...105,685,921
Ensembl chr13:105,646,908...105,686,174
|
|
| G
|
Duox1
|
dual oxidase 1
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of DUOX1 mRNA
|
CTD |
PMID:21540246 |
|
NCBI chr 3:129,714,125...129,749,186
Ensembl chr 3:129,714,149...129,749,187
|
|
| G
|
Dus1l
|
dihydrouridine synthase 1-like
|
increases expression
|
EXP
|
Progesterone results in increased expression of DUS1L mRNA
|
CTD |
PMID:16376865 |
|
NCBI chr10:106,055,519...106,062,656
Ensembl chr10:106,553,238...106,561,285
|
|
| G
|
Dus3l
|
dihydrouridine synthase 3-like
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of DUS3L mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr 9:1,680,619...1,685,784
Ensembl chr 9:1,675,819...1,686,367
|
|
| G
|
Dusp1
|
dual specificity phosphatase 1
|
multiple interactions increases expression
|
ISO
|
[Progesterone co-treated with Estradiol] results in increased expression of DUSP1 mRNA Progesterone results in increased expression of DUSP1 mRNA
|
CTD |
PMID:17404688 PMID:21795739 |
|
NCBI chr10:17,184,853...17,187,646
Ensembl chr10:17,184,823...17,187,644
|
|
| G
|
Dusp22
|
dual specificity phosphatase 22
|
increases expression
|
ISO
|
Progesterone results in increased expression of DUSP22 mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr17:33,780,980...33,831,241
Ensembl chr17:33,989,637...34,039,895
|
|
| G
|
Dusp26
|
dual specificity phosphatase 26
|
increases expression
|
ISO
|
Progesterone results in increased expression of DUSP26 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr16:67,744,830...67,752,673
Ensembl chr16:67,744,842...67,752,101
|
|
| G
|
Dusp5
|
dual specificity phosphatase 5
|
increases expression
|
ISO
|
Progesterone results in increased expression of DUSP5 mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr 1:262,543,774...262,557,201
Ensembl chr 1:262,543,738...262,562,417
|
|
| G
|
Dusp6
|
dual specificity phosphatase 6
|
increases expression decreases expression multiple interactions
|
ISO
|
Progesterone results in increased expression of DUSP6 mRNA Progesterone results in decreased expression of DUSP6 mRNA [Estradiol co-treated with Progesterone] results in decreased expression of DUSP6 mRNA
|
CTD |
PMID:18037150 PMID:20660070 PMID:20864642 |
|
NCBI chr 7:35,979,502...35,983,834
Ensembl chr 7:35,977,921...35,983,833
|
|
| G
|
Dxo
|
decapping exoribonuclease
|
multiple interactions increases expression
|
ISO
|
[Progesterone co-treated with Estradiol] results in increased expression of DXO mRNA Progesterone results in increased expression of DXO mRNA
|
CTD |
PMID:18692832 |
|
NCBI chr20:3,997,953...4,000,115
Ensembl chr20:3,997,955...4,000,037
|
|
| G
|
Dynlrb1
|
dynein light chain roadblock-type 1
|
affects expression
|
ISO
|
Progesterone affects the expression of DYNLRB1 mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr 3:143,742,427...143,764,227
Ensembl chr 3:164,202,953...164,224,409
|
|
| G
|
Dyrk2
|
dual specificity tyrosine phosphorylation regulated kinase 2
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of DYRK2 mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr 7:54,348,724...54,381,363
Ensembl chr 7:56,235,276...56,265,942
|
|
| G
|
E2f1
|
E2F transcription factor 1
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of E2F1 mRNA
|
CTD |
PMID:16966611 |
|
NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:163,524,739...163,535,563
|
|
| G
|
E2f8
|
E2F transcription factor 8
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of E2F8 mRNA
|
CTD |
PMID:21795739 |
|
NCBI chr 1:107,701,985...107,720,538
Ensembl chr 1:107,701,985...107,720,009
|
|
| G
|
Eaf2
|
ELL associated factor 2
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of EAF2 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr11:77,465,585...77,509,993
Ensembl chr11:77,406,020...77,509,993
|
|
| G
|
Ebi3
|
Epstein-Barr virus induced 3
|
increases expression multiple interactions
|
ISO
|
Progesterone results in increased expression of EBI3 mRNA TGFB1 protein promotes the reaction [Progesterone results in increased expression of EBI3 mRNA]
|
CTD |
PMID:21768398 |
|
NCBI chr 9:861,441...874,731
Ensembl chr 9:870,792...874,973
|
|
| G
|
Ebp
|
EBP, cholestenol delta-isomerase
|
increases expression
|
ISO
|
Progesterone results in increased expression of EBP mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr X:16,971,372...16,977,782
Ensembl chr X:16,971,405...16,977,781
|
|
| G
|
Ece2
|
endothelin-converting enzyme 2
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of ECE2 mRNA
|
CTD |
PMID:21453500 |
|
NCBI chr11:93,767,559...93,782,896
Ensembl chr11:93,767,559...93,793,292
|
|
| G
|
Ech1
|
enoyl-CoA hydratase 1
|
increases expression
|
EXP
|
Progesterone results in increased expression of ECH1 mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr 1:93,241,076...93,248,314
Ensembl chr 1:93,241,734...93,248,440
|
|
| G
|
Echdc2
|
enoyl CoA hydratase domain containing 2
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of ECHDC2 mRNA
|
CTD |
PMID:21540246 |
|
NCBI chr 5:128,144,241...128,163,611
Ensembl chr 5:128,144,425...128,163,610
|
|
| G
|
Echs1
|
enoyl-CoA hydratase, short chain 1
|
increases expression
|
EXP
|
Progesterone results in increased expression of ECHS1 mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr 1:204,324,679...204,333,506
Ensembl chr 1:204,324,682...204,333,506
|
|
| G
|
Ecm1
|
extracellular matrix protein 1
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of ECM1 mRNA
|
CTD |
PMID:20226447 |
|
NCBI chr 2:185,976,439...185,981,656
Ensembl chr 2:185,976,440...185,981,606
|
|
| G
|
Edn1
|
endothelin 1
|
multiple interactions increases expression decreases expression
|
ISO EXP
|
Progesterone inhibits the reaction [Estradiol results in increased expression of EDN1 mRNA]; Progesterone inhibits the reaction [Estradiol results in increased secretion of EDN1 protein] Progesterone results in increased expression of EDN1 mRNA Progesterone results in decreased expression of EDN1 mRNA
|
CTD |
PMID:20726854 PMID:21795739 PMID:22238285 |
|
NCBI chr17:22,660,799...22,666,687
Ensembl chr17:22,660,799...22,666,687
|
|
| G
|
Edn3
|
endothelin 3
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of EDN3 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 3:183,980,458...184,004,958
Ensembl chr 3:183,980,668...184,005,329
|
|
| G
|
Ednra
|
endothelin receptor type A
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of EDNRA mRNA
|
CTD |
PMID:21795739 |
|
NCBI chr19:47,137,360...47,207,961
Ensembl chr19:47,137,771...47,201,284
|
|
| G
|
Ednrb
|
endothelin receptor type B
|
multiple interactions increases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of EDNRB mRNA Progesterone results in increased expression of EDNRB mRNA
|
CTD |
PMID:20660070 PMID:21540246 |
|
NCBI chr15:87,055,490...87,086,765
Ensembl chr15:87,057,691...87,086,765
|
|
| G
|
Eef2k
|
eukaryotic elongation factor-2 kinase
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of EEF2K mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 1:184,824,420...184,888,048
Ensembl chr 1:184,824,420...184,888,048
|
|
| G
|
Efemp1
|
EGF containing fibulin extracellular matrix protein 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of EFEMP1 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr14:106,811,769...106,890,961
Ensembl chr14:106,802,304...106,892,808
|
|
| G
|
Efhd1
|
EF-hand domain family, member D1
|
increases expression
|
ISO
|
Progesterone results in increased expression of EFHD1 mRNA
|
CTD |
PMID:20864642 |
|
NCBI chr 9:95,386,155...95,432,800
Ensembl chr 9:95,386,169...95,432,798
|
|
| G
|
Efna1
|
ephrin A1
|
increases expression
|
ISO
|
Progesterone results in increased expression of EFNA1 mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr 2:174,681,676...174,689,061
Ensembl chr 2:176,979,434...176,988,726
|
|
| G
|
Efnb2
|
ephrin B2
|
multiple interactions decreases expression
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of EFNB2 mRNA Progesterone results in decreased expression of EFNB2 mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr16:80,783,389...80,827,420
Ensembl chr16:87,485,198...87,529,208
|
|
| G
|
Efs
|
embryonal Fyn-associated substrate
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of EFS mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr15:32,362,401...32,374,490
Ensembl chr15:32,361,843...32,371,743
|
|
| G
|
Egf
|
epidermal growth factor
|
multiple interactions increases expression
|
ISO EXP
|
Mifepristone inhibits the reaction [Progesterone promotes the reaction [EGF protein results in increased phosphorylation of MAPK1 protein]]; Mifepristone inhibits the reaction [Progesterone promotes the reaction [EGF protein results in increased phosphorylation of MAPK3 protein]]; Progesterone promotes the reaction [EGF protein affects the localization of FOS protein]; Progesterone promotes the reaction [EGF protein results in increased expression of FOS mRNA]; Progesterone promotes the reaction [EGF protein results in increased expression of FOS protein]; Progesterone promotes the reaction [EGF protein results in increased phosphorylation of EGFR protein]; Progesterone promotes the reaction [EGF protein results in increased phosphorylation of MAPK1 protein]; Progesterone promotes the reaction [EGF protein results in increased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [Progesterone promotes the reaction [EGF protein results in increased phosphorylation of MAPK1 protein]]; U 0126 inhibits the reaction [Progesterone promotes the reaction [EGF protein results in increased phosphorylation of MAPK3 protein]] Progesterone results in increased expression of EGF mRNA
|
CTD |
PMID:16175315 PMID:18591650 |
|
NCBI chr 2:220,893,660...220,976,331
Ensembl chr 2:220,893,660...220,976,297
|
|
| G
|
Egfl6
|
EGF-like-domain, multiple 6
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of EGFL6 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr X:31,515,752...31,573,699
Ensembl chr X:31,515,767...31,574,632
|
|
| G
|
Egfr
|
epidermal growth factor receptor
|
multiple interactions increases expression
|
ISO EXP
|
[Progesterone co-treated with Estradiol] results in increased expression of EGFR mRNA; [RTKI cpd results in decreased activity of EGFR protein] inhibits the reaction [FSHB protein results in increased chemical synthesis of Progesterone]; Progesterone promotes the reaction [EGF protein results in increased phosphorylation of EGFR protein] [Estrogens co-treated with Progesterone] results in increased expression of EGFR mRNA; [Estrogens co-treated with Progesterone] results in increased expression of EGFR protein Progesterone results in increased expression of EGFR mRNA Estradiol promotes the reaction [Progesterone inhibits the reaction [perfluorooctanoic acid results in decreased expression of EGFR protein]]; Progesterone inhibits the reaction [perfluorooctanoic acid results in decreased expression of EGFR protein]; Progesterone promotes the reaction [Estradiol inhibits the reaction [perfluorooctanoic acid results in decreased expression of EGFR protein]] Progesterone results in increased expression of EGFR protein
|
CTD |
PMID:16175315 PMID:18591650 PMID:18692832 PMID:21258428 PMID:21520325 PMID:22414604 More...
|
|
NCBI chr14:95,378,626...95,551,358
Ensembl chr14:95,378,626...95,551,358
|
|
| G
|
Egln3
|
egl-9 family hypoxia-inducible factor 3
|
increases expression
|
EXP
|
Progesterone results in increased expression of EGLN3 mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr 6:77,385,549...77,411,015
Ensembl chr 6:77,385,549...77,411,015
|
|
| G
|
Egr1
|
early growth response 1
|
multiple interactions decreases expression increases expression affects expression
|
ISO EXP
|
[Progesterone co-treated with Estradiol] results in decreased expression of EGR1 mRNA Mifepristone inhibits the reaction [Progesterone inhibits the reaction [bisphenol A results in increased expression of EGR1 mRNA]]; Mifepristone inhibits the reaction [Progesterone inhibits the reaction [Estradiol results in increased expression of EGR1 mRNA]]; Progesterone inhibits the reaction [bisphenol A results in increased expression of EGR1 mRNA]; Progesterone inhibits the reaction [Estradiol results in increased expression of EGR1 mRNA] Progesterone results in decreased expression of EGR1 mRNA Progesterone results in increased expression of EGR1 mRNA Progesterone affects the expression of EGR1 mRNA
|
CTD |
PMID:17404688 PMID:20726854 PMID:21795739 PMID:23461915 PMID:25461906 |
|
NCBI chr18:26,737,078...26,740,877
Ensembl chr18:26,736,838...26,740,843
|
|
| G
|
Egr2
|
early growth response 2
|
increases expression multiple interactions
|
EXP ISO
|
Progesterone results in increased expression of EGR2 mRNA; Progesterone results in increased expression of EGR2 protein [Estradiol co-treated with Progesterone] results in decreased expression of EGR2 mRNA
|
CTD |
PMID:17478888 PMID:20660070 |
|
NCBI chr20:21,050,149...21,055,201
Ensembl chr20:21,050,149...21,057,748
|
|
| G
|
Egr3
|
early growth response 3
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of EGR3 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr15:51,560,482...51,565,778
Ensembl chr15:51,560,344...51,565,712
|
|
| G
|
Ehbp1
|
EH domain binding protein 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of EHBP1 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr14:96,093,327...96,380,502
Ensembl chr14:100,294,585...100,546,579
|
|
| G
|
Ehd1
|
EH-domain containing 1
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of EHD1 mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr 1:213,009,113...213,031,488
Ensembl chr 1:213,008,049...213,031,485
|
|
| G
|
Ehd2
|
EH-domain containing 2
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of EHD2 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 1:85,767,757...85,786,974
Ensembl chr 1:85,768,667...85,786,943
|
|
| G
|
Ehf
|
ets homologous factor
|
multiple interactions decreases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of EHF mRNA Progesterone results in decreased expression of EHF mRNA
|
CTD |
PMID:20660070 PMID:22238285 |
|
NCBI chr 3:110,094,770...110,134,991
Ensembl chr 3:110,096,756...110,134,928
|
|
| G
|
Eif1
|
eukaryotic translation initiation factor 1
|
increases expression
|
ISO
|
Progesterone results in increased expression of EIF1 mRNA
|
CTD |
PMID:21795739 |
|
NCBI chr10:85,246,751...85,248,842
Ensembl chr 5:25,895,968...25,896,654 Ensembl chr10:25,895,968...25,896,654
|
|
| G
|
Eif2s3
|
eukaryotic translation initiation factor 2 subunit gamma
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in increased expression of EIF2S3 mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr X:58,916,513...58,939,923
Ensembl chr X:62,910,293...62,934,489
|
|
| G
|
Eif4ebp1
|
eukaryotic translation initiation factor 4E binding protein 1
|
multiple interactions
|
EXP
|
[Estradiol co-treated with Progesterone co-treated with Methylnitrosourea] results in increased phosphorylation of EIF4EBP1 protein
|
CTD |
PMID:22465879 |
|
NCBI chr16:71,495,457...71,508,845
Ensembl chr16:71,487,930...71,508,874
|
|
| G
|
Eif4ebp2
|
eukaryotic translation initiation factor 4E binding protein 2
|
affects expression
|
ISO
|
Progesterone affects the expression of EIF4EBP2 mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr20:29,379,444...29,400,110
Ensembl chr20:29,922,260...29,942,922
|
|
| G
|
Eif4g3
|
eukaryotic translation initiation factor 4 gamma, 3
|
affects expression
|
ISO
|
Progesterone affects the expression of EIF4G3 mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr 5:150,197,410...150,418,862
Ensembl chr 5:155,481,378...155,702,194
|
|
| G
|
Eif5
|
eukaryotic translation initiation factor 5
|
increases expression
|
ISO
|
Progesterone results in increased expression of EIF5 mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr 6:136,410,333...136,418,827
Ensembl chr 6:136,407,440...136,418,821
|
|
| G
|
Elf3
|
E74 like ETS transcription factor 3
|
increases expression
|
ISO
|
Progesterone results in increased expression of ELF3 mRNA
|
CTD |
PMID:18497975 |
|
NCBI chr13:49,242,265...49,247,102
Ensembl chr13:49,242,267...49,247,380
|
|
| G
|
Ell3
|
elongation factor for RNA polymerase II 3
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of ELL3 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 3:128,866,755...128,870,896
Ensembl chr 3:128,864,777...128,870,852
|
|
| G
|
Eloa
|
elongin A
|
increases expression
|
EXP
|
Progesterone results in increased expression of ELOA mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr 5:148,231,600...148,246,760
Ensembl chr 5:153,515,066...153,530,916
|
|
| G
|
Elovl1
|
ELOVL fatty acid elongase 1
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of ELOVL1 mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr 5:137,246,781...137,251,351
Ensembl chr 5:137,246,849...137,251,352
|
|
| G
|
Elovl6
|
ELOVL fatty acid elongase 6
|
increases expression
|
ISO EXP
|
Progesterone results in increased expression of ELOVL6 mRNA Progesterone results in increased expression of ELOVL6 protein
|
CTD |
PMID:18070364 PMID:23180365 |
|
NCBI chr 2:220,738,095...220,845,528
Ensembl chr 2:220,738,064...220,845,549
|
|
| G
|
Elovl7
|
ELOVL fatty acid elongase 7
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of ELOVL7 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 2:41,522,695...41,592,021
Ensembl chr 2:41,522,738...41,592,020
|
|
| G
|
Emb
|
embigin
|
decreases expression multiple interactions
|
ISO
|
Progesterone results in decreased expression of EMB mRNA NCOA2 protein affects the reaction [Progesterone results in decreased expression of EMB mRNA]
|
CTD |
PMID:17556502 |
|
NCBI chr 2:50,803,468...50,858,001
Ensembl chr 2:50,801,973...50,862,920
|
|
| G
|
Emp2
|
epithelial membrane protein 2
|
increases expression
|
ISO
|
Progesterone results in increased expression of EMP2 mRNA
|
CTD |
PMID:20864642 |
|
NCBI chr10:5,866,869...5,901,533
Ensembl chr10:5,866,922...5,901,532
|
|
| G
|
Enc1
|
ectodermal-neural cortex 1
|
multiple interactions decreases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of ENC1 mRNA; [Progesterone co-treated with Estradiol] results in decreased expression of ENC1 mRNA Progesterone results in decreased expression of ENC1 mRNA
|
CTD |
PMID:17404688 PMID:20660070 |
|
NCBI chr 2:30,285,274...30,297,194
Ensembl chr 2:30,283,736...30,315,721
|
|
| G
|
Eng
|
endoglin
|
multiple interactions increases expression
|
ISO
|
Mifepristone inhibits the reaction [Progesterone results in increased expression of ENG mRNA]
|
CTD |
PMID:20431248 |
|
NCBI chr 3:36,332,190...36,370,324
Ensembl chr 3:36,326,202...36,370,933
|
|
| G
|
Enpep
|
glutamyl aminopeptidase
|
increases expression
|
ISO
|
Progesterone results in increased expression of ENPEP mRNA
|
CTD |
PMID:17404688 PMID:20864642 PMID:21540246 |
|
NCBI chr 2:220,456,258...220,526,218
Ensembl chr 2:220,456,278...220,526,218
|
|
| G
|
Enpp1
|
ectonucleotide pyrophosphatase/phosphodiesterase 1
|
increases expression
|
ISO
|
Progesterone results in increased expression of ENPP1 mRNA
|
CTD |
PMID:20864642 |
|
NCBI chr 1:22,518,051...22,583,044
Ensembl chr 1:22,518,069...22,583,044
|
|
| G
|
Enpp2
|
ectonucleotide pyrophosphatase/phosphodiesterase 2
|
affects expression
|
ISO
|
Progesterone affects the expression of ENPP2 mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr 7:88,092,140...88,214,758
Ensembl chr 7:88,092,140...88,214,957
|
|
| G
|
Enpp3
|
ectonucleotide pyrophosphatase/phosphodiesterase 3
|
increases expression
|
ISO
|
Progesterone results in increased expression of ENPP3 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 1:20,563,700...20,635,044
Ensembl chr 1:22,382,964...22,454,314
|
|
| G
|
Enpp4
|
ectonucleotide pyrophosphatase/phosphodiesterase 4
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of ENPP4 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 9:16,888,923...16,898,860
Ensembl chr 9:24,360,272...24,396,152
|
|
| G
|
Entpd8
|
ectonucleoside triphosphate diphosphohydrolase 8
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of ENTPD8 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 3:28,283,392...28,295,686
Ensembl chr 3:28,285,777...28,293,686
|
|
| G
|
Entrep1
|
endosomal transmembrane epsin interactor 1
|
increases expression
|
ISO
|
Progesterone results in increased expression of ENTREP1 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 1:231,018,987...231,073,474
Ensembl chr 1:231,018,987...231,102,708
|
|
| G
|
Epb41l4a
|
erythrocyte membrane protein band 4.1 like 4A
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of EPB41L4A mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr18:25,680,169...25,890,998
Ensembl chr18:25,680,171...25,888,498
|
|
| G
|
Epb41l4b
|
erythrocyte membrane protein band 4.1 like 4B
|
multiple interactions decreases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of EPB41L4B mRNA Progesterone results in decreased expression of EPB41L4B mRNA
|
CTD |
PMID:20660070 PMID:22238285 |
|
NCBI chr 5:76,486,886...76,647,752
Ensembl chr 5:76,486,902...76,647,752
|
|
| G
|
Epb41l5
|
erythrocyte membrane protein band 4.1 like 5
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of EPB41L5 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr13:33,221,705...33,321,400
Ensembl chr13:33,223,589...33,321,133
|
|
| G
|
Epha3
|
Eph receptor A3
|
increases expression
|
ISO
|
Progesterone results in increased expression of EPHA3 mRNA
|
CTD |
PMID:21795739 |
|
NCBI chr11:14,585,041...14,920,721
Ensembl chr11:14,586,727...14,920,425
|
|
| G
|
Epha6
|
Eph receptor A6
|
decreases expression
|
EXP
|
Progesterone results in decreased expression of EPHA6 mRNA
|
CTD |
PMID:21770760 |
|
NCBI chr11:39,757,501...40,708,901
Ensembl chr11:53,226,954...54,166,987
|
|
| G
|
Epha7
|
Eph receptor A7
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of EPHA7 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 5:47,771,776...47,925,189
Ensembl chr 5:47,771,865...47,925,058
|
|
| G
|
Epha8
|
Eph receptor A8
|
increases expression
|
ISO
|
Progesterone results in increased expression of EPHA8 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 5:149,166,107...149,193,515
Ensembl chr 5:154,449,566...154,476,966
|
|
| G
|
Erbb4
|
erb-b2 receptor tyrosine kinase 4
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of ERBB4 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 9:69,523,733...70,596,743
Ensembl chr 9:76,973,227...78,045,772
|
|
| G
|
Erbin
|
erbb2 interacting protein
|
increases expression
|
ISO
|
Progesterone results in increased expression of ERBIN mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr 2:34,926,962...35,028,440
Ensembl chr 2:36,660,399...36,762,153
|
|
| G
|
Erc2
|
ELKS/RAB6-interacting/CAST family member 2
|
increases expression
|
ISO
|
Progesterone results in increased expression of ERC2 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr16:2,819,399...3,680,258
Ensembl chr16:2,819,512...3,680,258
|
|
| G
|
Erp27
|
endoplasmic reticulum protein 27
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of ERP27 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 4:171,535,845...171,552,848
Ensembl chr 4:171,535,847...171,553,072
|
|
| G
|
Errfi1
|
ERBB receptor feedback inhibitor 1
|
affects expression increases expression
|
ISO
|
Progesterone affects the expression of ERRFI1 mRNA Progesterone results in increased expression of ERRFI1 mRNA
|
CTD |
PMID:17251523 PMID:20864642 PMID:21795739 |
|
NCBI chr 5:166,606,841...166,620,124
Ensembl chr 5:166,606,834...166,620,432
|
|
| G
|
Esr1
|
estrogen receptor 1
|
decreases expression increases activity decreases activity multiple interactions
|
ISO EXP
|
Progesterone results in decreased expression of ESR1 mRNA Progesterone results in increased activity of ESR1 protein Progesterone results in decreased activity of ESR1 protein ESR1 protein promotes the reaction [[Estradiol co-treated with Progesterone] results in increased expression of IHH mRNA]; ESR1 protein promotes the reaction [[Estradiol co-treated with Progesterone] results in increased expression of LIF mRNA]; Progesterone inhibits the reaction [ESR1 protein promotes the reaction [Estradiol results in increased expression of LPL mRNA]] Progesterone results in decreased expression of ESR1 mRNA; Progesterone results in decreased expression of ESR1 mRNA alternative form; Progesterone results in decreased expression of ESR1 protein ESR1 protein affects the reaction [Progesterone results in increased expression of GREB1 mRNA]; ESR1 protein affects the reaction [Progesterone results in increased expression of SGK1 mRNA]; Fulvestrant inhibits the reaction [Progesterone results in increased activity of ESR1 protein] [Estradiol co-treated with Progesterone] results in decreased expression of ESR1 mRNA; [Estradiol co-treated with Progesterone] results in decreased expression of ESR1 mRNA alternative form; [Estradiol co-treated with Progesterone] results in increased expression of ESR1 mRNA; bisphenol A inhibits the reaction [[Estradiol co-treated with Progesterone] results in increased expression of ESR1 protein]; Diethylstilbestrol inhibits the reaction [[Estradiol co-treated with Progesterone] results in increased expression of ESR1 protein]; Progesterone inhibits the reaction [Estradiol results in increased expression of ESR1 mRNA]
|
CTD |
PMID:16002535 PMID:17974624 PMID:18037150 PMID:18653720 PMID:19094096 PMID:21277368 PMID:22562034 PMID:25012808 PMID:25210133 PMID:33405908 More...
|
|
NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:43,644,392...43,900,354
|
|
| G
|
Esr2
|
estrogen receptor 2
|
increases expression decreases expression multiple interactions affects binding
|
ISO EXP
|
Progesterone metabolite results in increased expression of ESR2 mRNA Progesterone results in decreased expression of ESR2 mRNA [Estradiol co-treated with Progesterone] results in decreased expression of ESR2 mRNA; Progesterone inhibits the reaction [Estradiol results in increased expression of ESR2 mRNA] Progesterone binds to ESR2 protein ESR2 affects the reaction [[Estradiol co-treated with Progesterone] results in increased expression of OXT mRNA]; Progesterone inhibits the reaction [ESR2 protein promotes the reaction [Estradiol results in increased expression of LPL mRNA]]
|
CTD |
PMID:12834440 PMID:17683929 PMID:17974624 PMID:19094096 PMID:19913605 PMID:21277368 More...
|
|
NCBI chr 6:100,589,553...100,645,240
Ensembl chr 6:100,545,206...100,644,709
|
|
| G
|
Esrra
|
estrogen related receptor, alpha
|
increases expression
|
ISO
|
Progesterone results in increased expression of ESRRA mRNA
|
CTD |
PMID:15968320 |
|
NCBI chr 1:213,533,309...213,543,432
Ensembl chr 1:213,533,310...213,543,811
|
|
| G
|
Etl4
|
enhancer trap locus 4
|
increases expression
|
ISO
|
Progesterone results in increased expression of KIAA1217 mRNA
|
CTD |
PMID:20864642 |
|
NCBI chr17:82,841,075...83,304,868
Ensembl chr17:87,403,819...88,213,158
|
|
| G
|
Etv1
|
ETS variant transcription factor 1
|
increases expression multiple interactions
|
ISO
|
Progesterone results in increased expression of ETV1 mRNA [Estradiol co-treated with Progesterone] results in decreased expression of ETV1 mRNA
|
CTD |
PMID:18070364 PMID:20660070 |
|
NCBI chr 6:61,316,836...61,408,985
Ensembl chr 6:61,317,429...61,408,959
|
|
| G
|
Etv5
|
ETS variant transcription factor 5
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of ETV5 mRNA
|
CTD |
PMID:20864642 |
|
NCBI chr11:92,113,171...92,170,758
Ensembl chr11:92,113,224...92,170,767
|
|
| G
|
Evi2a
|
ecotropic viral integration site 2A
|
increases expression multiple interactions
|
ISO
|
Progesterone results in increased expression of EVI2A mRNA [Estradiol co-treated with Progesterone] results in decreased expression of EVI2A mRNA
|
CTD |
PMID:18070364 PMID:20660070 |
|
NCBI chr10:64,983,727...64,987,627
Ensembl chr10:64,983,705...64,999,516
|
|
| G
|
Exo1
|
exonuclease 1
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of EXO1 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr13:87,809,725...87,834,654
Ensembl chr13:90,342,018...90,366,861
|
|
| G
|
Ezh2
|
enhancer of zeste 2 polycomb repressive complex 2 subunit
|
increases expression
|
ISO
|
Progesterone results in increased expression of EZH2 mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr 4:77,624,223...77,698,598
Ensembl chr 4:77,624,223...77,687,183
|
|
| G
|
F10
|
coagulation factor X
|
increases expression
|
ISO
|
Progesterone results in increased expression of F10 mRNA
|
CTD |
PMID:18497975 |
|
NCBI chr16:83,170,973...83,190,280
Ensembl chr16:83,170,977...83,190,280
|
|
| G
|
F13a1
|
coagulation factor XIII A1 chain
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of F13A1 mRNA; [Progesterone co-treated with Estradiol] results in decreased expression of F13A1 mRNA
|
CTD |
PMID:17404688 PMID:20660070 |
|
NCBI chr17:28,021,197...28,197,960
Ensembl chr17:28,020,845...28,197,948
|
|
| G
|
F2
|
coagulation factor II, thrombin
|
multiple interactions
|
ISO
|
[Hirudins binds to and results in decreased activity of F2 protein] promotes the reaction [CGB3 protein results in increased chemical synthesis of Progesterone] [Hirudins binds to and results in decreased activity of F2 protein] which results in increased chemical synthesis of Progesterone
|
CTD |
PMID:22207716 |
|
NCBI chr 3:98,051,958...98,065,246
Ensembl chr 3:98,051,960...98,065,246
|
|
| G
|
F2r
|
coagulation factor II (thrombin) receptor
|
affects expression increases expression multiple interactions
|
ISO EXP
|
Progesterone affects the expression of F2R mRNA Progesterone results in increased expression of F2R mRNA [N3-cyclopropyl-7-((4-(1-methylethyl)phenyl)methyl)-7H-pyrrolo(3, 2-f)quinazoline-1,3-diamine binds to and results in decreased activity of F2R protein] which results in increased chemical synthesis of Progesterone [C186 65 binds to and results in increased activity of F2R protein] inhibits the reaction [CGB3 protein results in increased chemical synthesis of Progesterone]; [N3-cyclopropyl-7-((4-(1-methylethyl)phenyl)methyl)-7H-pyrrolo(3, 2-f)quinazoline-1,3-diamine binds to and results in decreased activity of F2R protein] promotes the reaction [CGB3 protein results in increased chemical synthesis of Progesterone]
|
CTD |
PMID:11733402 PMID:17251523 PMID:21770760 PMID:22207716 |
|
NCBI chr 2:26,869,343...26,885,856
Ensembl chr 2:28,604,066...28,620,579
|
|
| G
|
F2rl1
|
F2R like trypsin receptor 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of F2RL1 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 2:28,507,003...28,519,954
Ensembl chr 2:28,507,003...28,519,954
|
|
| G
|
F2rl2
|
coagulation factor II (thrombin) receptor-like 2
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of F2RL2 mRNA
|
CTD |
PMID:20864642 |
|
NCBI chr 2:28,706,766...28,711,808
Ensembl chr 2:28,706,501...28,712,473
|
|
| G
|
F2rl3
|
F2R like thrombin or trypsin receptor 3
|
multiple interactions
|
ISO
|
[GYPGKF-NH(2) binds to and results in increased activity of F2RL3 protein] inhibits the reaction [CGB3 protein results in increased chemical synthesis of Progesterone]
|
CTD |
PMID:22207716 |
|
NCBI chr16:17,151,516...17,153,509
Ensembl chr16:17,151,516...17,153,823
|
|
| G
|
F3
|
coagulation factor III, tissue factor
|
multiple interactions increases expression
|
ISO EXP
|
[Estradiol co-treated with Progesterone] results in increased expression of F3 mRNA; Mifepristone inhibits the reaction [Progesterone results in increased expression of F3 protein] Progesterone results in increased expression of F3 mRNA Progesterone results in increased expression of F3 mRNA; Progesterone results in increased expression of F3 protein
|
CTD |
PMID:15562024 PMID:20660070 PMID:20726854 PMID:21795739 |
|
NCBI chr 2:212,511,675...212,523,375
Ensembl chr 2:212,511,680...212,523,369
|
|
| G
|
Faah
|
fatty acid amide hydrolase
|
increases expression increases activity
|
ISO
|
Progesterone results in increased expression of FAAH mRNA; Progesterone results in increased expression of FAAH protein Progesterone results in increased activity of FAAH protein
|
CTD |
PMID:16154199 |
|
NCBI chr 5:134,716,545...134,735,396
Ensembl chr 5:134,716,545...134,735,396
|
|
| G
|
Fabp3
|
fatty acid binding protein 3
|
increases expression
|
EXP
|
Progesterone results in increased expression of FABP3 mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr 5:147,936,027...147,942,870
Ensembl chr 5:147,936,119...147,942,881
|
|
| G
|
Fabp4
|
fatty acid binding protein 4
|
increases expression
|
ISO EXP
|
Progesterone results in increased expression of FABP4 mRNA
|
CTD |
PMID:15713686 PMID:21770760 |
|
NCBI chr 2:93,488,251...93,492,961
Ensembl chr 2:93,488,271...93,492,972
|
|
| G
|
Fabp5
|
fatty acid binding protein 5
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of FABP5 mRNA
|
CTD |
PMID:19693291 |
|
NCBI chr 2:93,672,451...93,676,186
Ensembl chr 2:93,672,458...93,676,127
|
|
| G
|
Fadd
|
Fas associated via death domain
|
increases expression
|
ISO
|
Progesterone results in increased expression of FADD mRNA
|
CTD |
PMID:21549006 |
|
NCBI chr 1:209,169,245...209,175,423
Ensembl chr 1:209,169,318...209,174,976
|
|
| G
|
Fads1
|
fatty acid desaturase 1
|
increases expression
|
ISO
|
Progesterone results in increased expression of FADS1 mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr 1:216,252,605...216,267,618
Ensembl chr 1:216,252,602...216,267,615
|
|
| G
|
Fads2
|
fatty acid desaturase 2
|
increases expression
|
ISO
|
Progesterone results in increased expression of FADS2 mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr 1:216,132,277...216,172,190
Ensembl chr 1:216,133,676...216,172,066
|
|
| G
|
Fads3
|
fatty acid desaturase 3
|
increases expression
|
ISO
|
Progesterone results in increased expression of FADS3 mRNA
|
CTD |
PMID:21795739 |
|
NCBI chr 1:216,110,547...216,127,431
Ensembl chr 1:216,110,201...216,141,758
|
|
| G
|
Faim
|
Fas apoptotic inhibitory molecule
|
multiple interactions increases expression
|
ISO
|
[Progesterone co-treated with Estradiol] results in increased expression of FAIM mRNA Progesterone results in increased expression of FAIM mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr 8:99,543,877...99,569,499
Ensembl chr 8:108,423,221...108,440,151
|
|
| G
|
Fam107a
|
family with sequence similarity 107, member A
|
increases expression
|
ISO
|
Progesterone results in increased expression of FAM107A mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr15:19,038,726...19,060,644
Ensembl chr15:19,038,616...19,065,219
|
|
| G
|
Fam110c
|
family with sequence similarity 110, member C
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of FAM110C mRNA
|
CTD |
PMID:21540246 |
|
NCBI chr 6:53,366,013...53,372,270
Ensembl chr 6:53,352,870...53,401,117
|
|
| G
|
Fam171b
|
family with sequence similarity 171, member B
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of FAM171B mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 3:89,337,566...89,392,973
Ensembl chr 3:89,337,661...89,392,971
|
|
| G
|
Fam181b
|
family with sequence similarity 181, member B
|
increases expression
|
ISO
|
Progesterone results in increased expression of FAM181B mRNA
|
CTD |
PMID:21540246 |
|
NCBI chr 1:156,578,821...156,580,318
Ensembl chr 1:156,491,094...156,595,845
|
|
| G
|
Fam43a
|
family with sequence similarity 43, member A
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of FAM43A mRNA
|
CTD |
PMID:20864642 |
|
NCBI chr11:83,633,165...83,636,313
Ensembl chr11:83,633,154...83,695,297
|
|
| G
|
Fam83g
|
family with sequence similarity 83, member G
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of FAM83G mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr10:46,363,029...46,388,030
Ensembl chr10:46,862,369...46,886,277
|
|
| G
|
Fanci
|
FA complementation group I
|
increases expression
|
ISO
|
Progesterone results in increased expression of FANCI mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr 1:133,327,264...133,383,661
Ensembl chr 1:142,736,653...142,792,999
|
|
| G
|
Fat2
|
FAT atypical cadherin 2
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of FAT2 mRNA
|
CTD |
PMID:18037150 PMID:22238285 |
|
NCBI chr10:39,864,765...39,957,027
Ensembl chr10:39,864,766...39,956,902
|
|
| G
|
Faxdc2
|
fatty acid hydroxylase domain containing 2
|
increases expression
|
ISO
|
Progesterone results in increased expression of FAXDC2 mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr10:42,245,808...42,271,679
Ensembl chr10:42,747,524...42,781,458
|
|
| G
|
Fbln1
|
fibulin 1
|
increases expression
|
ISO
|
Progesterone results in increased expression of FBLN1 mRNA
|
CTD |
PMID:15774544 |
|
NCBI chr 7:118,190,347...118,269,965
Ensembl chr 7:118,190,478...118,269,965
|
|
| G
|
Fbln2
|
fibulin 2
|
increases expression
|
ISO
|
Progesterone results in increased expression of FBLN2 mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr 4:125,261,464...125,321,030
Ensembl chr 4:125,261,607...125,321,029
|
|
| G
|
Fbln5
|
fibulin 5
|
increases expression
|
ISO
|
Progesterone results in increased expression of FBLN5 mRNA
|
CTD |
PMID:21795739 |
|
NCBI chr 6:126,664,100...126,742,847
Ensembl chr 6:126,664,100...126,746,296
|
|
| G
|
Fbn2
|
fibrillin 2
|
increases expression
|
EXP
|
Progesterone results in increased expression of FBN2 mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr18:53,696,197...53,901,992
Ensembl chr18:53,697,708...53,902,191
|
|
| G
|
Fbxl7
|
F-box and leucine-rich repeat protein 7
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of FBXL7 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 2:78,870,236...79,239,697
Ensembl chr 2:78,871,287...79,239,697
|
|
| G
|
Fbxo11
|
F-box protein 11
|
increases expression
|
ISO
|
Progesterone results in increased expression of FBXO11 mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr 6:12,240,348...12,316,223
Ensembl chr 6:12,239,801...12,316,221
|
|
| G
|
Fbxo32
|
F-box protein 32
|
multiple interactions
|
ISO
|
[Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with Estradiol] results in increased expression of FBXO32 mRNA; NR3C2 protein promotes the reaction [[Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with Estradiol] results in increased expression of FBXO32 mRNA]
|
CTD |
PMID:23275455 |
|
NCBI chr 7:91,620,925...91,654,491
Ensembl chr 7:91,620,925...91,654,491
|
|
| G
|
Fcgr3a
|
Fc gamma receptor 3A
|
increases expression
|
ISO
|
Progesterone results in increased expression of FCGR3A mRNA
|
CTD |
PMID:21540246 |
|
NCBI chr13:85,782,636...85,792,656
Ensembl chr13:85,782,490...85,792,651
|
|
| G
|
Fcsk
|
fucose kinase
|
affects response to substance
|
ISO
|
FCSK gene SNP affects the susceptibility to Progesterone
|
CTD |
PMID:25622337 |
|
NCBI chr19:38,849,130...38,874,497
Ensembl chr19:55,739,842...55,800,496
|
|
| G
|
Fdft1
|
farnesyl diphosphate farnesyl transferase 1
|
increases expression
|
ISO
|
Progesterone results in increased expression of FDFT1 mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr15:41,588,114...41,616,168
Ensembl chr15:41,588,117...41,616,168
|
|
| G
|
Fdps
|
farnesyl diphosphate synthase
|
increases expression affects expression
|
ISO
|
Progesterone results in increased expression of FDPS mRNA Progesterone affects the expression of FDPS mRNA
|
CTD |
PMID:17251523 PMID:18070364 |
|
NCBI chr 2:176,795,192...176,804,816
Ensembl chr 2:176,795,192...176,807,136
|
|
| G
|
Fen1
|
flap structure-specific endonuclease 1
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of FEN1 mRNA
|
CTD |
PMID:16966611 |
|
NCBI chr 1:216,270,016...216,274,873
Ensembl chr 1:216,269,163...216,275,016
|
|
| G
|
Fermt1
|
FERM domain containing kindlin 1
|
decreases expression multiple interactions
|
ISO
|
Progesterone results in decreased expression of FERMT1 mRNA [Estradiol co-treated with Progesterone] results in decreased expression of FERMT1 mRNA; [Progesterone co-treated with Estradiol] results in decreased expression of FERMT1 mRNA
|
CTD |
PMID:17404688 PMID:20660070 |
|
NCBI chr 3:120,171,301...120,213,555
Ensembl chr 3:140,624,434...140,666,419
|
|
| G
|
Fermt2
|
FERM domain containing kindlin 2
|
increases expression
|
ISO
|
Progesterone results in increased expression of FERMT2 mRNA
|
CTD |
PMID:20864642 |
|
NCBI chr15:18,682,927...18,751,959
Ensembl chr15:21,162,605...21,258,115
|
|
| G
|
Fga
|
fibrinogen alpha chain
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in increased expression of FGA mRNA
|
CTD |
PMID:17404688 PMID:18692832 |
|
NCBI chr 2:168,374,120...168,381,523
Ensembl chr 2:170,672,012...170,679,577
|
|
| G
|
Fgb
|
fibrinogen beta chain
|
increases expression
|
ISO
|
Progesterone results in increased expression of FGB mRNA
|
CTD |
PMID:21540246 |
|
NCBI chr 2:170,693,966...170,700,875
Ensembl chr 2:170,692,965...170,705,434
|
|
| G
|
Fgd4
|
FYVE, RhoGEF and PH domain containing 4
|
increases expression
|
ISO
|
Progesterone results in increased expression of FGD4 mRNA
|
CTD |
PMID:21795739 |
|
NCBI chr11:84,399,989...84,551,013
Ensembl chr11:97,904,182...98,055,190
|
|
| G
|
Fgf13
|
fibroblast growth factor 13
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in increased expression of FGF13 mRNA
|
CTD |
PMID:18692832 |
|
NCBI chr X:137,276,498...137,800,056
Ensembl chr X:142,312,391...142,423,536
|
|
| G
|
Fgf18
|
fibroblast growth factor 18
|
multiple interactions decreases expression
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of FGF18 mRNA Progesterone results in decreased expression of FGF18 mRNA
|
CTD |
PMID:17404688 PMID:18037150 |
|
NCBI chr10:18,210,240...18,241,929
Ensembl chr10:18,210,512...18,240,933
|
|
| G
|
Fgf2
|
fibroblast growth factor 2
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in increased expression of FGF2 mRNA
|
CTD |
PMID:18692832 |
|
NCBI chr 2:122,164,454...122,218,796
Ensembl chr 2:122,164,454...122,224,493
|
|
| G
|
Fgf4
|
fibroblast growth factor 4
|
decreases expression
|
EXP
|
Progesterone results in decreased expression of FGF4 mRNA
|
CTD |
PMID:21770760 |
|
NCBI chr 1:209,453,229...209,457,085
Ensembl chr 1:209,453,229...209,457,085
|
|
| G
|
Fgf9
|
fibroblast growth factor 9
|
multiple interactions decreases expression
|
ISO
|
[FGF9 protein co-treated with FSHB protein] affects the abundance of Progesterone; [Progesterone co-treated with Estradiol] results in decreased expression of FGF9 mRNA; FGF9 protein inhibits the reaction [[IGF1 protein co-treated with FSHB protein] results in increased abundance of Progesterone]; FGF9 protein inhibits the reaction [IGF1 protein promotes the reaction [Bucladesine results in increased abundance of Progesterone]]; FGF9 protein inhibits the reaction [IGF1 protein promotes the reaction [Colforsin results in increased abundance of Progesterone]]; FGF9 protein inhibits the reaction [IGF1 protein results in increased abundance of Progesterone]; FGF9 protein promotes the reaction [Bucladesine results in increased abundance of Progesterone] Progesterone results in decreased expression of FGF9 mRNA
|
CTD |
PMID:17404688 PMID:22238285 PMID:22798350 |
|
NCBI chr15:36,325,552...36,369,995
Ensembl chr15:36,325,599...36,367,926
|
|
| G
|
Fgfbp1
|
fibroblast growth factor binding protein 1
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of FGFBP1 mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr14:71,316,171...71,319,965
Ensembl chr14:71,317,065...71,320,309
|
|
| G
|
Fgfr2
|
fibroblast growth factor receptor 2
|
affects expression multiple interactions
|
ISO
|
Progesterone affects the expression of FGFR2 mRNA [Estradiol co-treated with Progesterone] results in decreased expression of FGFR2 mRNA
|
CTD |
PMID:17251523 PMID:20660070 |
|
NCBI chr 1:194,175,703...194,280,914
Ensembl chr 1:194,175,705...194,280,914
|
|
| G
|
Fgl1
|
fibrinogen-like 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of FGL1 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr16:57,824,127...57,854,413
Ensembl chr16:57,824,200...57,854,429
|
|
| G
|
Fgl2
|
fibrinogen-like 2
|
multiple interactions increases expression
|
ISO
|
[Progesterone co-treated with Estradiol] results in increased expression of FGL2 mRNA Progesterone results in increased expression of FGL2 mRNA
|
CTD |
PMID:17404688 PMID:22238285 |
|
NCBI chr 4:14,602,762...14,608,405
Ensembl chr 4:14,602,771...14,608,405
|
|
| G
|
Fh
|
fumarate hydratase
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of FH mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr13:90,056,565...90,082,450
Ensembl chr13:90,056,570...90,089,627
|
|
| G
|
Fhl2
|
four and a half LIM domains 2
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of FHL2 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 9:52,881,091...52,954,540
Ensembl chr 9:52,880,998...52,923,326
|
|
| G
|
Fhod3
|
formin homology 2 domain containing 3
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of FHOD3 mRNA
|
CTD |
PMID:20864642 |
|
NCBI chr18:16,267,830...16,700,508
Ensembl chr18:16,267,977...16,700,508
|
|
| G
|
Fibin
|
fin bud initiation factor homolog
|
increases expression
|
ISO
|
Progesterone results in increased expression of FIBIN mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 3:117,396,973...117,399,244
Ensembl chr 3:117,391,724...117,399,479
|
|
| G
|
Filip1l
|
filamin A interacting protein 1-like
|
increases expression
|
ISO
|
Progesterone results in increased expression of FILIP1L mRNA
|
CTD |
PMID:21540246 |
|
NCBI chr11:56,403,467...56,646,422
Ensembl chr11:56,410,582...56,646,402
|
|
| G
|
Fjx1
|
four-jointed box kinase 1
|
multiple interactions decreases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of FJX1 mRNA; [Progesterone co-treated with Estradiol] results in decreased expression of FJX1 mRNA Progesterone results in decreased expression of FJX1 mRNA
|
CTD |
PMID:17404688 PMID:20660070 PMID:20864642 |
|
NCBI chr 3:88,774,220...88,776,321
Ensembl chr 3:109,227,170...109,232,479
|
|
| G
|
Fkbp11
|
FKBP prolyl isomerase 11
|
affects expression
|
ISO
|
Progesterone affects the expression of FKBP11 mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr 7:131,750,828...131,757,784
Ensembl chr 7:131,750,672...131,770,123
|
|
| G
|
Fkbp5
|
FKBP prolyl isomerase 5
|
multiple interactions increases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of FKBP5 mRNA; [Progesterone co-treated with Estradiol] results in increased expression of FKBP5 mRNA; Arsenic inhibits the reaction [Progesterone results in increased expression of FKBP5 mRNA]
|
CTD |
PMID:17404688 PMID:18037150 PMID:19693291 PMID:20660070 PMID:20864642 PMID:21795739 PMID:33047385 More...
|
|
NCBI chr20:6,458,931...6,577,227
Ensembl chr20:6,458,940...6,543,118
|
|
| G
|
Flrt2
|
fibronectin leucine rich transmembrane protein 2
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of FLRT2 mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr 6:120,507,998...120,603,133
Ensembl chr 6:120,507,689...120,609,004
|
|
| G
|
Flt1
|
Fms related receptor tyrosine kinase 1
|
affects expression
|
ISO
|
Progesterone affects the expression of FLT1 mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr12:12,333,050...12,504,750
Ensembl chr12:12,333,430...12,504,750
|
|
| G
|
Fmn1
|
formin 1
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of FMN1 mRNA
|
CTD |
PMID:21795739 |
|
NCBI chr 3:100,101,103...100,485,652
Ensembl chr 3:120,555,431...120,933,124
|
|
| G
|
Fmo3
|
flavin containing dimethylaniline monoxygenase 3
|
increases expression
|
EXP
|
Progesterone results in increased expression of FMO3 mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr13:77,838,899...77,868,869
Ensembl chr13:77,842,602...77,861,256
|
|
| G
|
Fn1
|
fibronectin 1
|
decreases expression multiple interactions
|
ISO
|
Progesterone results in decreased expression of FN1 mRNA [Progesterone co-treated with Estradiol] results in decreased expression of FN1 mRNA
|
CTD |
PMID:18070364 PMID:20226447 |
|
NCBI chr 9:80,645,507...80,714,200
Ensembl chr 9:80,645,507...80,714,137
|
|
| G
|
Fndc1
|
fibronectin type III domain containing 1
|
multiple interactions decreases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of FNDC1 mRNA Progesterone results in decreased expression of FNDC1 mRNA
|
CTD |
PMID:20660070 PMID:22238285 |
|
NCBI chr 1:47,281,839...47,364,247
Ensembl chr 1:49,686,856...49,769,263
|
|
| G
|
Fndc3a
|
fibronectin type III domain containing 3a
|
increases expression
|
ISO
|
Progesterone results in increased expression of FNDC3A mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr15:47,689,909...47,867,354
Ensembl chr15:54,099,510...54,276,407
|
|
| G
|
Folr1
|
folate receptor alpha
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of FOLR1 mRNA; [Progesterone co-treated with Estradiol] results in decreased expression of FOLR1 mRNA
|
CTD |
PMID:18692832 PMID:20660070 |
|
NCBI chr 1:165,631,462...165,650,430
Ensembl chr 1:165,631,462...165,642,669
|
|
| G
|
Fos
|
Fos proto-oncogene, AP-1 transcription factor subunit
|
multiple interactions increases expression decreases expression
|
ISO EXP
|
[Estradiol co-treated with Progesterone] results in increased expression of FOS mRNA; [Progesterone co-treated with Estradiol] results in decreased expression of FOS mRNA; Progesterone promotes the reaction [EGF protein affects the localization of FOS protein]; Progesterone promotes the reaction [EGF protein results in increased expression of FOS mRNA]; Progesterone promotes the reaction [EGF protein results in increased expression of FOS protein] [Estrogens co-treated with Progesterone] results in increased expression of FOS protein [estradiol 3-benzoate co-treated with Progesterone] results in increased abundance of FOS protein; [Estradiol co-treated with Progesterone] results in increased expression of FOS mRNA Progesterone results in increased expression of FOS mRNA Progesterone results in decreased expression of FOS mRNA
|
CTD |
PMID:16175315 PMID:16376865 PMID:18556351 PMID:18692832 PMID:19847363 PMID:20660070 PMID:21258428 PMID:22577852 More...
|
|
NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598
|
|
| G
|
Fosb
|
FosB proto-oncogene, AP-1 transcription factor subunit
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of FOSB mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 1:88,082,324...88,089,506
Ensembl chr 1:88,082,127...88,089,477
|
|
| G
|
Fosl1
|
FOS like 1, AP-1 transcription factor subunit
|
increases expression
|
ISO
|
Progesterone results in increased expression of FOSL1 mRNA
|
CTD |
PMID:19000923 |
|
NCBI chr 1:212,183,885...212,192,391
Ensembl chr 1:212,183,833...212,192,391
|
|
| G
|
Foxa2
|
forkhead box A2
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of FOXA2 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 3:155,923,305...155,927,508
Ensembl chr 3:155,923,307...155,928,757
|
|
| G
|
Foxo1
|
forkhead box O1
|
multiple interactions increases expression
|
ISO
|
[Progesterone co-treated with Estradiol] inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime promotes the reaction [[NR1I3 protein co-treated with FOXO1 protein co-treated with HNF4A protein co-treated with NCOA1 protein] binds to CYP2C9 promoter]]; Progesterone inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime inhibits the reaction [FOXO1 protein binds to G6PC1 promoter]]; Progesterone inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime promotes the reaction [[NR1I3 protein co-treated with FOXO1 protein co-treated with HNF4A protein co-treated with NCOA1 protein] binds to CYP2C9 promoter]]; Progesterone promotes the reaction [Estradiol inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime inhibits the reaction [FOXO1 protein binds to G6PC1 promoter]]] Progesterone results in increased expression of FOXO1 mRNA; Progesterone results in increased expression of FOXO1A mRNA
|
CTD |
PMID:20864642 PMID:21768169 PMID:21795739 |
|
NCBI chr 2:138,462,974...138,541,420
Ensembl chr 2:138,462,697...138,541,419
|
|
| G
|
Foxp3
|
forkhead box P3
|
decreases expression multiple interactions
|
ISO
|
Progesterone results in decreased expression of FOXP3 mRNA [Progesterone co-treated with Estradiol] inhibits the reaction [Vaccines, Virus-Like Particle results in decreased expression of FOXP3 protein]; Progesterone inhibits the reaction [Vaccines, Virus-Like Particle results in decreased expression of FOXP3 protein] [Estradiol co-treated with Progesterone] results in decreased expression of FOXP3 mRNA
|
CTD |
PMID:19693291 PMID:20130130 |
|
NCBI chr X:17,580,380...17,601,181
Ensembl chr X:17,580,380...17,595,894
|
|
| G
|
Fpr1
|
formyl peptide receptor 1
|
affects expression
|
ISO
|
Progesterone affects the expression of FPR1 mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr 1:67,417,991...67,429,813
Ensembl chr 1:67,421,313...67,422,520
|
|
| G
|
Frmd3
|
FERM domain containing 3
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of FRMD3 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 5:87,764,755...88,031,091
Ensembl chr 5:92,810,736...93,077,325
|
|
| G
|
Frmd4a
|
FERM domain containing 4A
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of FRMD4A mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr17:73,667,787...74,258,487
Ensembl chr17:78,579,277...79,167,663
|
|
| G
|
Frmd6
|
FERM domain containing 6
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of FRMD6 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 6:89,345,983...89,419,579
Ensembl chr 6:95,081,985...95,155,560
|
|
| G
|
Fry
|
FRY microtubule binding protein
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of FRY mRNA
|
CTD |
PMID:20864642 |
|
NCBI chr12:9,530,360...9,773,391
Ensembl chr12:9,530,360...9,897,603
|
|
| G
|
Frzb
|
frizzled-related protein
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of FRZB mRNA
|
CTD |
PMID:19693291 |
|
NCBI chr 3:85,739,162...85,772,168
Ensembl chr 3:85,739,165...85,772,096
|
|
| G
|
Fscn1
|
fascin actin-bundling protein 1
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of FSCN1 mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr12:11,597,042...11,610,183
Ensembl chr12:16,710,601...16,723,734
|
|
| G
|
Fshb
|
follicle stimulating hormone subunit beta
|
multiple interactions increases abundance increases secretion increases chemical synthesis decreases expression increases expression
|
ISO EXP
|
1,3-bis(4-hydroxyphenyl)-4-methyl-5-(4-(2-piperidinylethoxy)phenol)-1H-pyrazole inhibits the reaction [TGFB1 protein promotes the reaction [FSHB protein results in increased abundance of Progesterone]]; [4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in decreased activity of [SMAD2 protein co-treated with SMAD3 protein]] promotes the reaction [FSHB protein results in increased chemical synthesis of Progesterone]; [6,7-dimethyl-2-(2E)-3-(1-methyl-2-phenyl-1H-pyrrolo(2,3-b)pyridin-3-yl-prop-2-enoyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride results in decreased activity of SMAD3 protein] inhibits the reaction [FSHB protein results in increased chemical synthesis of Progesterone]; [CGA protein co-treated with FSHB protein] results in increased abundance of Progesterone; [CGA protein co-treated with FSHB protein] results in increased secretion of Progesterone; [FGF9 protein co-treated with FSHB protein] affects the abundance of Progesterone; [FSHB protein co-treated with Testosterone] results in increased chemical synthesis of Progesterone; [IGF1 protein co-treated with FSHB protein] results in increased abundance of Progesterone; [RTKI cpd results in decreased activity of EGFR protein] inhibits the reaction [FSHB protein results in increased chemical synthesis of Progesterone]; Carbaryl inhibits the reaction [FSHB protein results in increased secretion of Progesterone]; FGF9 protein inhibits the reaction [[IGF1 protein co-treated with FSHB protein] results in increased abundance of Progesterone]; finrozole inhibits the reaction [FSHB protein results in increased secretion of Progesterone]; Fulvestrant inhibits the reaction [TGFB1 protein promotes the reaction [FSHB protein results in increased abundance of Progesterone]]; GDF9 protein inhibits the reaction [INHBA protein inhibits the reaction [FSHB protein results in increased secretion of Progesterone]]; INHA mutant form inhibits the reaction [FSHB protein results in increased secretion of Progesterone]; INHA mutant form inhibits the reaction [GDF9 protein inhibits the reaction [INHBA protein inhibits the reaction [FSHB protein results in increased secretion of Progesterone]]]; INHBA protein inhibits the reaction [FSHB protein results in increased secretion of Progesterone]; Lipopolysaccharides inhibits the reaction [FSHB protein results in increased abundance of Progesterone]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[FSHB protein co-treated with Testosterone] results in increased chemical synthesis of Progesterone]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [FSHB protein results in increased secretion of Progesterone]; PHB1 protein inhibits the reaction [FSHB protein results in increased secretion of Progesterone]; T-2 Toxin inhibits the reaction [FSHB protein results in increased secretion of Progesterone]; T0901317 inhibits the reaction [[CGA protein co-treated with FSHB protein] results in increased abundance of Progesterone]; TGFB1 protein promotes the reaction [FSHB protein results in increased abundance of Progesterone]; Trichlorfon inhibits the reaction [FSHB protein results in increased abundance of Progesterone]; U 0126 inhibits the reaction [Lipopolysaccharides inhibits the reaction [FSHB protein results in increased abundance of Progesterone]] NOG protein inhibits the reaction [Octreotide inhibits the reaction [FSHB protein results in increased abundance of Progesterone]]; NOG protein inhibits the reaction [pasireotide inhibits the reaction [FSHB protein results in increased abundance of Progesterone]] Progesterone results in decreased expression of FSHB protein 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane inhibits the reaction [FSHB protein results in increased abundance of Progesterone]; 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [[FSHB protein co-treated with TGFB1 protein] results in increased abundance of Progesterone]; [BMP15 protein results in decreased expression of STAR mRNA] inhibits the reaction [FSHB protein results in increased abundance of Progesterone]; [BMP2 protein results in decreased expression of STAR mRNA] inhibits the reaction [FSHB protein results in increased abundance of Progesterone]; [BMP4 protein results in decreased expression of STAR mRNA] inhibits the reaction [FSHB protein results in increased abundance of Progesterone]; [BMP6 protein results in decreased expression of STAR mRNA] inhibits the reaction [FSHB protein results in increased abundance of Progesterone]; [BMP7 protein results in decreased expression of STAR mRNA] inhibits the reaction [FSHB protein results in increased abundance of Progesterone]; [FSHB protein co-treated with CGB3 protein] inhibits the reaction [Puromycin Aminonucleoside results in decreased abundance of Progesterone]; [FSHB protein co-treated with TGFB1 protein] results in increased abundance of Progesterone; [FSHB protein results in increased expression of CYP11A1 mRNA] which results in increased abundance of Progesterone; [FSHB protein results in increased expression of CYP19A1 mRNA] which results in increased abundance of Progesterone; [FSHB protein results in increased expression of HSD3B2 mRNA] which results in increased abundance of Progesterone; [FSHB protein results in increased expression of STAR mRNA] which results in increased abundance of Progesterone; [Triclosan co-treated with FSHB protein] results in increased secretion of Progesterone; AG 538 inhibits the reaction [FSHB protein results in increased abundance of Progesterone]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide promotes the reaction [FSHB protein results in increased abundance of Progesterone]; Dihydrotestosterone inhibits the reaction [FSHB protein results in increased abundance of Progesterone]; GH1 protein inhibits the reaction [BMP4 protein inhibits the reaction [FSHB protein results in increased abundance of Progesterone]]; GH1 protein inhibits the reaction [BMP6 protein inhibits the reaction [FSHB protein results in increased abundance of Progesterone]]; GH1 protein inhibits the reaction [BMP7 protein inhibits the reaction [FSHB protein results in increased abundance of Progesterone]]; GH1 protein promotes the reaction [[FSHB protein results in increased expression of CYP11A1 mRNA] which results in increased abundance of Progesterone]; GH1 protein promotes the reaction [[FSHB protein results in increased expression of HSD3B2 mRNA] which results in increased abundance of Progesterone]; GH1 protein promotes the reaction [[FSHB protein results in increased expression of STAR mRNA] which results in increased abundance of Progesterone]; GH1 protein promotes the reaction [FSHB protein results in increased abundance of Progesterone]; IGF1 protein inhibits the reaction [BMP15 protein inhibits the reaction [FSHB protein results in increased abundance of Progesterone]]; IGF1 protein inhibits the reaction [BMP2 protein inhibits the reaction [FSHB protein results in increased abundance of Progesterone]]; IGF1 protein inhibits the reaction [BMP4 protein inhibits the reaction [FSHB protein results in increased abundance of Progesterone]]; IGF1 protein inhibits the reaction [BMP6 protein inhibits the reaction [FSHB protein results in increased abundance of Progesterone]]; IGF1 protein inhibits the reaction [BMP7 protein inhibits the reaction [FSHB protein results in increased abundance of Progesterone]]; IGF1 protein promotes the reaction [[FSHB protein results in increased expression of CYP11A1 mRNA] which results in increased abundance of Progesterone]; IGF1 protein promotes the reaction [[FSHB protein results in increased expression of CYP19A1 mRNA] which results in increased abundance of Progesterone]; IGF1 protein promotes the reaction [[FSHB protein results in increased expression of HSD3B2 mRNA] which results in increased abundance of Progesterone]; IGF1 protein promotes the reaction [[FSHB protein results in increased expression of STAR mRNA] which results in increased abundance of Progesterone]; IGF1 protein promotes the reaction [FSHB protein results in increased abundance of Progesterone]; INHBA protein inhibits the reaction [FSHB protein results in increased secretion of Progesterone]; Metformin inhibits the reaction [FSHB protein results in increased secretion of Progesterone]; Methoxychlor metabolite inhibits the reaction [FSHB protein results in increased abundance of Progesterone]; NOG protein promotes the reaction [GH1 protein promotes the reaction [FSHB protein results in increased abundance of Progesterone]]; Octreotide inhibits the reaction [FSHB protein results in increased abundance of Progesterone]; pasireotide inhibits the reaction [FSHB protein results in increased abundance of Progesterone]; pyrazolanthrone inhibits the reaction [FSHB protein results in increased abundance of Progesterone]; RARRES2 protein inhibits the reaction [FSHB protein results in increased abundance of Progesterone]; tyrphostin AG 1024 inhibits the reaction [FSHB protein results in increased abundance of Progesterone]; U 0126 inhibits the reaction [FSHB protein results in increased abundance of Progesterone] Progesterone results in increased expression of FSHB mRNA
|
CTD |
PMID:15781295 PMID:15967414 PMID:16413094 PMID:16574160 PMID:16675544 PMID:16737795 PMID:16760380 PMID:17099214 PMID:17329077 PMID:17954979 PMID:18325989 PMID:18511507 PMID:18535249 PMID:19081562 PMID:19228890 PMID:19336472 PMID:19729004 PMID:20660033 PMID:20926582 PMID:21520325 PMID:21826657 PMID:22067323 PMID:22798350 PMID:22948218 PMID:23137853 PMID:23254195 PMID:30447264 PMID:30951242 More...
|
|
NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:114,003,262...114,007,072
|
|
| G
|
Fst
|
follistatin
|
multiple interactions increases expression
|
ISO
|
FST protein inhibits the reaction [BMP6 protein inhibits the reaction [Colforsin results in increased secretion of Progesterone]]; FST protein inhibits the reaction [INHBA protein inhibits the reaction [Colforsin results in increased secretion of Progesterone]] [Estradiol co-treated with Progesterone co-treated with Corn Oil] results in increased expression of FST mRNA Progesterone results in increased expression of FST mRNA; Progesterone results in increased expression of FST mRNA alternative form
|
CTD |
PMID:18936084 PMID:22238285 PMID:22285243 PMID:32186404 |
|
NCBI chr 2:47,856,345...47,863,670
Ensembl chr 2:47,856,345...47,863,491
|
|
| G
|
Fxyd3
|
FXYD domain-containing ion transport regulator 3
|
increases expression
|
ISO
|
Progesterone results in increased expression of FXYD3 mRNA
|
CTD |
PMID:18497975 |
|
NCBI chr 1:86,305,531...86,312,455
Ensembl chr 1:95,432,919...95,439,702
|
|
| G
|
Fxyd4
|
FXYD domain-containing ion transport regulator 4
|
decreases expression increases expression
|
ISO
|
Progesterone results in decreased expression of FXYD4 mRNA Progesterone results in increased expression of FXYD4 mRNA
|
CTD |
PMID:21540246 PMID:22238285 |
|
NCBI chr 4:151,109,779...151,113,659
Ensembl chr 4:152,782,181...152,786,039
|
|
| G
|
Fxyd5
|
FXYD domain-containing ion transport regulator 5
|
decreases expression
|
EXP
|
Progesterone results in decreased expression of FXYD5 mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr 1:86,267,937...86,277,329
Ensembl chr 1:95,395,146...95,405,364
|
|
| G
|
Fxyd6
|
FXYD domain-containing ion transport regulator 6
|
decreases expression
|
EXP
|
Progesterone results in decreased expression of FXYD6 mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr 8:54,575,578...54,602,715
Ensembl chr 8:54,575,591...54,602,715
|
|
| G
|
Fzd10
|
frizzled class receptor 10
|
multiple interactions decreases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of FZD10 mRNA Progesterone results in decreased expression of FZD10 mRNA
|
CTD |
PMID:20660070 PMID:22238285 |
|
NCBI chr12:28,098,371...28,101,566
Ensembl chr12:33,734,364...33,741,646
|
|
| G
|
Fzd5
|
frizzled class receptor 5
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of FZD5 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 9:73,606,860...73,614,039
Ensembl chr 9:73,606,860...73,618,612
|
|
| G
|
Fzd7
|
frizzled class receptor 7
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of FZD7 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 9:68,425,538...68,428,357
Ensembl chr 9:68,411,259...68,432,585
|
|
| G
|
Fzr1
|
fizzy and cell division cycle 20 related 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of FZR1 protein; FZR1 mutant form inhibits the reaction [Progesterone affects the localization of CDKN1B protein]
|
CTD |
PMID:23029392 |
|
NCBI chr 7:8,982,765...8,994,689
Ensembl chr 7:8,989,769...8,995,199
|
|
| G
|
G0s2
|
G0/G1switch 2
|
increases expression affects expression multiple interactions
|
ISO
|
Progesterone results in increased expression of G0S2 mRNA Progesterone affects the expression of G0S2 mRNA [Estradiol co-treated with Progesterone] results in decreased expression of G0S2 mRNA; perfluorooctanoic acid inhibits the reaction [Progesterone affects the expression of G0S2 mRNA]; Progesterone inhibits the reaction [perfluorooctanoic acid inhibits the reaction [Progesterone affects the expression of G0S2 mRNA]]
|
CTD |
PMID:20660070 PMID:21795739 PMID:31896193 |
|
NCBI chr13:107,335,036...107,335,948
Ensembl chr13:107,335,036...107,336,293
|
|
| G
|
G6pc1
|
glucose-6-phosphatase catalytic subunit 1
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in decreased expression of G6PC1 mRNA]; [Progesterone co-treated with Estradiol] inhibits the reaction [Phenobarbital results in decreased expression of G6PC1 mRNA]; NR1I3 mutant form inhibits the reaction [Progesterone inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in decreased expression of G6PC1 mRNA]]; NR1I3 mutant form inhibits the reaction [Progesterone inhibits the reaction [Phenobarbital results in decreased expression of G6PC1 mRNA]]; Progesterone inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime inhibits the reaction [FOXO1 protein binds to G6PC1 promoter]]; Progesterone inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in decreased expression of G6PC1 mRNA]; Progesterone inhibits the reaction [Phenobarbital results in decreased expression of G6PC1 mRNA]; Progesterone promotes the reaction [Estradiol inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime inhibits the reaction [FOXO1 protein binds to G6PC1 promoter]]] 1,4-bis(2-(3,5-dichloropyridyloxy))benzene inhibits the reaction [[Progesterone co-treated with Estradiol] results in increased expression of G6PC1 mRNA]; [Progesterone co-treated with Estradiol] results in increased expression of G6PC1 mRNA
|
CTD |
PMID:21768169 |
|
NCBI chr10:86,807,659...86,819,023
Ensembl chr10:86,757,899...86,818,033
|
|
| G
|
Gabbr1
|
gamma-aminobutyric acid type B receptor subunit 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of GABBR1 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr20:1,469,779...1,499,352
Ensembl chr20:1,469,779...1,498,607
|
|
| G
|
Gabpa
|
GA binding protein transcription factor subunit alpha
|
multiple interactions
|
EXP
|
[Progesterone co-treated with Norepinephrine] results in increased expression of GABPA mRNA
|
CTD |
PMID:16954335 |
|
NCBI chr11:23,888,586...23,917,612
Ensembl chr11:37,375,084...37,404,059
|
|
| G
|
Gabra2
|
gamma-aminobutyric acid type A receptor subunit alpha 2
|
increases expression
|
ISO
|
Progesterone results in increased expression of GABRA2 mRNA
|
CTD |
PMID:16000229 |
|
NCBI chr14:37,451,218...37,587,458
Ensembl chr14:37,450,683...37,587,457
|
|
| G
|
Gabra4
|
gamma-aminobutyric acid type A receptor subunit alpha 4
|
affects expression multiple interactions affects response to substance
|
EXP
|
Progesterone affects the expression of GABRA4 protein [Progesterone co-treated with estradiol 3-benzoate] results in decreased expression of GABRA4 mRNA GABRA4 protein affects the susceptibility to Progesterone
|
CTD |
PMID:12522171 PMID:15834956 PMID:19394921 |
|
NCBI chr14:36,590,782...36,667,724
Ensembl chr14:36,944,388...37,021,648
|
|
| G
|
Gabra5
|
gamma-aminobutyric acid type A receptor subunit alpha 5
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of GABRA5 mRNA
|
CTD |
PMID:16000229 |
|
NCBI chr 1:108,268,728...108,381,670
Ensembl chr 1:117,404,494...117,516,635
|
|
| G
|
Gabrb1
|
gamma-aminobutyric acid type A receptor subunit beta1
|
affects expression
|
EXP
|
Progesterone affects the expression of GABRB1 protein
|
CTD |
PMID:15834956 |
|
NCBI chr14:36,434,339...36,917,920
Ensembl chr14:36,434,352...36,902,893
|
|
| G
|
Gabrd
|
gamma-aminobutyric acid type A receptor subunit delta
|
affects expression decreases expression multiple interactions
|
EXP
|
Progesterone affects the expression of GABRD mRNA; Progesterone affects the expression of GABRD protein; Progesterone metabolite affects the expression of GABRD mRNA Progesterone results in decreased expression of GABRD protein Finasteride inhibits the reaction [Progesterone affects the expression of GABRD mRNA]; Finasteride inhibits the reaction [Progesterone affects the expression of GABRD protein]
|
CTD |
PMID:15834956 PMID:16879715 PMID:16914187 |
|
NCBI chr 5:165,958,508...165,970,407
Ensembl chr 5:171,240,789...171,253,094
|
|
| G
|
Gabre
|
gamma-aminobutyric acid type A receptor subunit epsilon
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of GABRE mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr X:150,060,035...150,078,773
Ensembl chr X:155,102,083...155,120,735
|
|
| G
|
Gabrg3
|
gamma-aminobutyric acid type A receptor subunit gamma 3
|
increases expression
|
ISO
|
Progesterone results in increased expression of GABRG3 mRNA
|
CTD |
PMID:16000229 |
|
NCBI chr 1:116,763,332...117,386,770
Ensembl chr 1:116,763,129...117,382,536
|
|
| G
|
Gabrp
|
gamma-aminobutyric acid type A receptor subunit pi
|
multiple interactions decreases expression increases expression affects localization
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of GABRP mRNA; HOXA10 protein affects the reaction [Progesterone affects the localization of GABRP protein]; HOXA10 protein affects the reaction [Progesterone results in increased expression of GABRP mRNA] Progesterone results in decreased expression of GABRP mRNA
|
CTD |
PMID:20103740 PMID:20660070 PMID:22238285 |
|
NCBI chr10:18,647,243...18,673,806
Ensembl chr10:18,647,243...18,673,727
|
|
| G
|
Gadd45a
|
growth arrest and DNA-damage-inducible, alpha
|
increases expression multiple interactions
|
ISO EXP
|
Progesterone results in increased expression of GADD45A mRNA [Estradiol co-treated with Progesterone] results in decreased expression of GADD45A mRNA
|
CTD |
PMID:18037150 PMID:20660070 PMID:20726854 |
|
NCBI chr 4:97,484,497...97,486,799
Ensembl chr 4:97,484,502...97,486,807
|
|
| G
|
Gadd45g
|
growth arrest and DNA-damage-inducible, gamma
|
affects expression
|
ISO
|
Progesterone affects the expression of GADD45G mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr17:13,528,606...13,530,351
Ensembl chr17:13,528,610...13,530,369
|
|
| G
|
Gal
|
galanin and GMAP prepropeptide
|
multiple interactions
|
EXP
|
[Estradiol co-treated with Progesterone] results in increased expression of GAL mRNA; [Estrogens co-treated with Progesterone] results in increased expression of GAL mRNA; Dizocilpine Maleate inhibits the reaction [[Estradiol co-treated with Progesterone] results in increased expression of GAL mRNA]; Pentobarbital inhibits the reaction [[Estrogens co-treated with Progesterone] results in increased expression of GAL mRNA]; Phenoxybenzamine inhibits the reaction [[Estrogens co-treated with Progesterone] results in increased expression of GAL mRNA]
|
CTD |
PMID:7512492 PMID:8730651 |
|
NCBI chr 1:200,650,439...200,655,302
Ensembl chr 1:210,079,702...210,084,229
|
|
| G
|
Galk2
|
galactokinase 2
|
increases expression
|
ISO
|
Progesterone results in increased expression of GALK2 mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr 3:113,110,057...113,243,014
Ensembl chr 3:133,563,538...133,696,528
|
|
| G
|
Galm
|
galactose mutarotase
|
affects expression
|
ISO
|
Progesterone affects the expression of GALM mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr 6:20,589,775...20,641,516
Ensembl chr 6:20,589,776...20,644,417
|
|
| G
|
Galnt10
|
polypeptide N-acetylgalactosaminyltransferase 10
|
affects response to substance
|
ISO
|
GALNT10 gene SNP affects the susceptibility to Progesterone
|
CTD |
PMID:25622337 |
|
NCBI chr10:41,821,216...41,967,618
Ensembl chr10:42,322,161...42,468,087
|
|
| G
|
Gap43
|
growth associated protein 43
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of GAP43 mRNA Progesterone inhibits the reaction [VPS54 mutant form results in increased expression of GAP43 mRNA]
|
CTD |
PMID:17404688 PMID:19693665 |
|
NCBI chr11:71,882,131...71,975,799
Ensembl chr11:71,882,131...71,975,797
|
|
| G
|
Gapdh
|
glyceraldehyde-3-phosphate dehydrogenase
|
increases expression
|
EXP
|
Progesterone results in increased expression of GAPDH mRNA
|
CTD |
PMID:16376865 |
|
NCBI chr 4:159,648,592...159,653,436
Ensembl chr 4:159,648,592...159,653,377
|
|
| G
|
Gar1
|
GAR1 ribonucleoprotein
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of GAR1 mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr 2:221,049,471...221,056,749
Ensembl chr 2:221,049,473...221,056,749
|
|
| G
|
Gars1
|
glycyl-tRNA synthetase 1
|
increases expression
|
ISO
|
Progesterone results in increased expression of GARS1 mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr 4:85,484,939...85,542,876
Ensembl chr 4:85,493,753...85,542,876
|
|
| G
|
Gas1
|
growth arrest-specific 1
|
increases expression
|
ISO
|
Progesterone results in increased expression of GAS1 mRNA
|
CTD |
PMID:21540246 |
|
NCBI chr17:4,487,716...4,490,701
Ensembl chr17:4,484,283...4,497,657
|
|
| G
|
Gas2l3
|
growth arrest-specific 2 like 3
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of GAS2L3 mRNA
|
CTD |
PMID:21795739 |
|
NCBI chr 7:25,690,929...25,726,806
Ensembl chr 7:25,693,660...25,716,942
|
|
| G
|
Gas6
|
growth arrest specific 6
|
multiple interactions increases expression
|
ISO EXP
|
[Estradiol co-treated with Progesterone] results in increased expression of GAS6 mRNA Progesterone results in increased expression of GAS6 mRNA
|
CTD |
PMID:20660070 PMID:20726854 PMID:22238285 |
|
NCBI chr16:76,045,430...76,075,904
Ensembl chr16:82,747,345...82,778,088
|
|
| G
|
Gask1b
|
golgi associated kinase 1B
|
increases expression
|
ISO
|
Progesterone results in increased expression of GASK1B mRNA
|
CTD |
PMID:21795739 |
|
NCBI chr 2:165,047,689...165,112,479
Ensembl chr 2:167,345,809...167,410,603
|
|
| G
|
Gast
|
gastrin
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in increased expression of GAST mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr10:85,264,832...85,269,393
Ensembl chr10:85,765,216...85,767,880
|
|
| G
|
Gata2
|
GATA binding protein 2
|
multiple interactions
|
ISO
|
[Progesterone results in increased activity of PGR protein] which results in increased expression of GATA2 mRNA
|
CTD |
PMID:15845616 |
|
NCBI chr 4:122,211,501...122,225,058
Ensembl chr 4:122,211,829...122,225,055
|
|
| G
|
Gata4
|
GATA binding protein 4
|
decreases expression multiple interactions
|
ISO
|
Progesterone results in decreased expression of GATA4 mRNA Mifepristone inhibits the reaction [Progesterone results in decreased expression of GATA4 mRNA]
|
CTD |
PMID:27264040 PMID:31566189 |
|
NCBI chr15:41,635,572...41,707,252
Ensembl chr15:41,635,572...41,681,609
|
|
| G
|
Gata6
|
GATA binding protein 6
|
increases expression
|
ISO
|
Progesterone results in increased expression of GATA6 mRNA
|
CTD |
PMID:21540246 |
|
NCBI chr18:2,188,121...2,219,532
Ensembl chr18:2,458,253...2,492,322
|
|
| G
|
Gatm
|
glycine amidinotransferase
|
decreases expression
|
EXP ISO
|
Progesterone results in decreased expression of GATM mRNA
|
CTD |
PMID:20726854 PMID:22238285 |
|
NCBI chr 3:130,112,508...130,137,664
Ensembl chr 3:130,112,509...130,129,355
|
|
| G
|
Gbp2
|
guanylate binding protein 2
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of GBP2 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 2:234,005,727...234,021,812
Ensembl chr 2:234,008,590...234,021,810
|
|
| G
|
Gbp4
|
guanylate binding protein 4
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of GBP4 mRNA
|
CTD |
PMID:20864642 |
|
NCBI chr 2:233,978,163...233,992,124
Ensembl chr 2:233,978,486...233,992,120
|
|
| G
|
Gclc
|
glutamate-cysteine ligase, catalytic subunit
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of GCLC mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 8:87,510,251...87,548,896
Ensembl chr 8:87,510,463...87,548,893
|
|
| G
|
Gcnt1
|
glucosaminyl (N-acetyl) transferase 1
|
increases expression multiple interactions
|
EXP ISO
|
Progesterone results in increased expression of GCNT1 mRNA [Estradiol co-treated with Progesterone] results in decreased expression of GCNT1 mRNA
|
CTD |
PMID:20660070 PMID:20726854 PMID:20864642 PMID:21795739 |
|
NCBI chr 1:224,145,104...224,182,496
Ensembl chr 1:224,141,108...224,185,741
|
|
| G
|
Gcsam
|
germinal center-associated, signaling and motility
|
affects expression
|
ISO
|
Progesterone affects the expression of GCSAM mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr11:55,195,757...55,207,011
Ensembl chr11:68,660,438...68,669,584
|
|
| G
|
Gda
|
guanine deaminase
|
increases expression
|
EXP
|
Progesterone results in increased expression of GDA mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr 1:228,333,401...228,408,901
Ensembl chr 1:228,333,364...228,409,348
|
|
| G
|
Gdf15
|
growth differentiation factor 15
|
increases expression decreases expression multiple interactions
|
ISO EXP
|
Progesterone results in increased expression of GDF15 mRNA Progesterone results in decreased expression of GDF15 mRNA [Estradiol co-treated with Progesterone] results in decreased expression of GDF15 mRNA
|
CTD |
PMID:18037150 PMID:20660070 PMID:20726854 PMID:22238285 |
|
NCBI chr16:18,838,436...18,842,022
Ensembl chr16:18,838,436...18,842,022
|
|
| G
|
Gdf5
|
growth differentiation factor 5
|
increases expression
|
ISO
|
Progesterone results in increased expression of GDF5 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 3:164,914,401...164,918,593
Ensembl chr 3:164,914,401...164,918,593
|
|
| G
|
Gdf9
|
growth differentiation factor 9
|
multiple interactions
|
ISO
|
GDF9 protein inhibits the reaction [INHBA protein inhibits the reaction [FSHB protein results in increased secretion of Progesterone]]; GDF9 protein inhibits the reaction [INHBA protein results in decreased secretion of Progesterone]; INHA mutant form inhibits the reaction [GDF9 protein inhibits the reaction [INHBA protein inhibits the reaction [FSHB protein results in increased secretion of Progesterone]]]
|
CTD |
PMID:20660033 |
|
NCBI chr10:37,589,200...37,599,970
Ensembl chr10:38,089,878...38,100,797
|
|
| G
|
Gdnf
|
glial cell derived neurotrophic factor
|
increases expression
|
ISO
|
Progesterone results in increased expression of GDNF mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 2:58,621,327...58,647,242
Ensembl chr 2:58,621,327...58,647,240
|
|
| G
|
Gdpd2
|
glycerophosphodiester phosphodiesterase domain containing 2
|
increases expression
|
ISO
|
Progesterone results in increased expression of GDPD2 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr X:69,866,395...69,875,419
Ensembl chr X:69,866,799...69,875,414
|
|
| G
|
Gem
|
GTP binding protein overexpressed in skeletal muscle
|
multiple interactions increases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of GEM mRNA Progesterone results in increased expression of GEM mRNA
|
CTD |
PMID:20660070 PMID:22238285 |
|
NCBI chr 5:30,011,641...30,022,554
Ensembl chr 5:30,011,592...30,022,542
|
|
| G
|
Gemin6
|
gem (nuclear organelle) associated protein 6
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of GEMIN6 mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr 6:14,786,090...14,790,617
Ensembl chr 6:20,538,325...20,542,852
|
|
| G
|
Gfap
|
glial fibrillary acidic protein
|
multiple interactions increases expression decreases expression
|
ISO EXP
|
[Estradiol co-treated with Progesterone] promotes the reaction [Cuprizone results in increased expression of GFAP mRNA] Progesterone results in increased expression of GFAP mRNA Progesterone results in decreased expression of GFAP protein Finasteride inhibits the reaction [Progesterone results in increased expression of GFAP mRNA]
|
CTD |
PMID:19031445 PMID:19360904 PMID:21770760 PMID:23157231 |
|
NCBI chr10:88,352,987...88,361,661
Ensembl chr10:88,352,986...88,361,685
|
|
| G
|
Gfi1
|
growth factor independent 1 transcriptional repressor
|
increases expression multiple interactions
|
ISO
|
Progesterone results in increased expression of GFI1 mRNA TGFB1 protein promotes the reaction [Progesterone results in increased expression of GFI1 mRNA]
|
CTD |
PMID:21768398 |
|
NCBI chr14:2,185,489...2,204,191
Ensembl chr14:2,187,286...2,196,730
|
|
| G
|
Gfpt2
|
glutamine-fructose-6-phosphate transaminase 2
|
increases expression
|
ISO
|
Progesterone results in increased expression of GFPT2 mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr10:34,616,146...34,662,420
Ensembl chr10:34,615,370...34,662,419
|
|
| G
|
Gfra2
|
GDNF family receptor alpha 2
|
increases expression
|
ISO
|
Progesterone results in increased expression of GFRA2 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr15:52,351,499...52,443,369
Ensembl chr15:52,351,514...52,477,782
|
|
| G
|
Gga1
|
golgi associated, gamma adaptin ear containing, ARF binding protein 1
|
affects expression
|
ISO
|
Progesterone affects the expression of GGA1 mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr 7:110,436,071...110,451,790
Ensembl chr 7:112,315,449...112,332,249
|
|
| G
|
Ggt5
|
gamma-glutamyltransferase 5
|
increases expression affects expression
|
ISO
|
Progesterone results in increased expression of GGT5 mRNA Progesterone affects the expression of GGT5 mRNA
|
CTD |
PMID:17251523 PMID:21540246 |
|
NCBI chr20:13,042,694...13,070,960
Ensembl chr20:13,042,696...13,070,892
|
|
| G
|
Ggt6
|
gamma-glutamyl transferase 6
|
increases expression
|
ISO
|
Progesterone results in increased expression of GGT6 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr10:57,550,447...57,553,461
Ensembl chr10:57,550,492...57,553,460
|
|
| G
|
Ggta1
|
glycoprotein alpha-galactosyltransferase 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of GGTA1 mRNA; Mifepristone inhibits the reaction [Progesterone affects the expression of GGTA1 mRNA]
|
CTD |
PMID:20660070 PMID:22414680 |
|
NCBI chr 3:18,732,985...18,824,916
Ensembl chr 3:39,130,467...39,206,870
|
|
| G
|
Gh1
|
growth hormone 1
|
multiple interactions increases secretion
|
ISO EXP
|
[Progesterone co-treated with Estradiol] results in increased secretion of GH1 protein GH1 protein inhibits the reaction [BMP4 protein inhibits the reaction [FSHB protein results in increased abundance of Progesterone]]; GH1 protein inhibits the reaction [BMP6 protein inhibits the reaction [FSHB protein results in increased abundance of Progesterone]]; GH1 protein inhibits the reaction [BMP7 protein inhibits the reaction [FSHB protein results in increased abundance of Progesterone]]; GH1 protein promotes the reaction [[FSHB protein results in increased expression of CYP11A1 mRNA] which results in increased abundance of Progesterone]; GH1 protein promotes the reaction [[FSHB protein results in increased expression of HSD3B2 mRNA] which results in increased abundance of Progesterone]; GH1 protein promotes the reaction [[FSHB protein results in increased expression of STAR mRNA] which results in increased abundance of Progesterone]; GH1 protein promotes the reaction [FSHB protein results in increased abundance of Progesterone]; NOG protein promotes the reaction [GH1 protein promotes the reaction [FSHB protein results in increased abundance of Progesterone]] Progesterone results in increased secretion of GH1 protein
|
CTD |
PMID:15772906 PMID:22067323 |
|
NCBI chr10:91,727,883...91,729,860
Ensembl chr10:91,727,884...91,729,859
|
|
| G
|
Ghr
|
growth hormone receptor
|
increases expression
|
EXP
|
Progesterone results in increased expression of GHR mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr 2:54,269,066...54,532,595
Ensembl chr 2:54,270,206...54,532,331
|
|
| G
|
Gipc2
|
GIPC PDZ domain containing family, member 2
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of GIPC2 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 2:243,690,742...243,770,199
Ensembl chr 2:243,690,748...243,770,199
|
|
| G
|
Gja1
|
gap junction protein, alpha 1
|
increases expression decreases expression
|
EXP ISO
|
Progesterone results in increased expression of GJA1 mRNA Progesterone results in decreased expression of GJA1 protein
|
CTD |
PMID:20726854 PMID:21558462 |
|
NCBI chr20:36,302,490...36,315,010
Ensembl chr20:36,302,352...36,319,689
|
|
| G
|
Gja4
|
gap junction protein, alpha 4
|
multiple interactions increases expression decreases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of GJA4 mRNA; [Progesterone co-treated with Estradiol] results in decreased expression of GJA4 mRNA Progesterone results in increased expression of GJA4 mRNA Progesterone results in decreased expression of GJA4 mRNA
|
CTD |
PMID:17404688 PMID:18692832 PMID:20660070 |
|
NCBI chr 5:144,917,791...144,920,324
Ensembl chr 5:144,914,147...144,921,216
|
|
| G
|
Gja5
|
gap junction protein, alpha 5
|
increases expression
|
EXP
|
Progesterone results in increased expression of GJA5 mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr 2:184,602,407...184,621,952
Ensembl chr 2:187,234,674...187,318,512
|
|
| G
|
Gjb2
|
gap junction protein, beta 2
|
affects expression decreases expression multiple interactions
|
ISO
|
Progesterone affects the expression of GJB2 mRNA Progesterone results in decreased expression of GJB2 mRNA Progesterone results in decreased expression of GJB2 protein [Estradiol co-treated with Progesterone] results in increased expression of GJB2 mRNA
|
CTD |
PMID:17251523 PMID:20660070 PMID:21558462 PMID:22238285 |
|
NCBI chr15:35,375,977...35,393,817
Ensembl chr15:35,375,692...35,393,877
|
|
| G
|
Gjb3
|
gap junction protein, beta 3
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of GJB3 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 5:139,649,227...139,654,970
Ensembl chr 5:144,933,696...144,940,280
|
|
| G
|
Gjb6
|
gap junction protein, beta 6
|
affects expression decreases expression
|
ISO
|
Progesterone affects the expression of GJB6 mRNA Progesterone results in decreased expression of GJB6 mRNA
|
CTD |
PMID:17251523 PMID:22238285 |
|
NCBI chr15:31,284,561...31,294,552
Ensembl chr15:35,398,770...35,410,849
|
|
| G
|
Gk
|
glycerol kinase
|
increases expression
|
ISO
|
Progesterone results in increased expression of GK mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr X:54,106,708...54,189,940
Ensembl chr X:54,112,214...54,196,701
|
|
| G
|
Glb1l2
|
galactosidase, beta 1-like 2
|
increases expression
|
ISO
|
Progesterone results in increased expression of GLB1L2 mRNA
|
CTD |
PMID:20864642 |
|
NCBI chr 8:25,115,462...25,166,843
Ensembl chr 8:33,390,678...33,442,695
|
|
| G
|
Gldc
|
glycine decarboxylase
|
increases expression
|
ISO
|
Progesterone results in increased expression of GLDC mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 1:237,296,753...237,375,620
Ensembl chr 1:237,296,753...237,375,604
|
|
| G
|
Gli1
|
GLI family zinc finger 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of GLI1 mRNA
|
CTD |
PMID:22958837 |
|
NCBI chr 7:65,042,237...65,054,888
Ensembl chr 7:65,042,237...65,054,540
|
|
| G
|
Gli2
|
GLI family zinc finger 2
|
affects expression
|
ISO
|
Progesterone affects the expression of GLI2 mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr13:29,946,882...30,163,589
Ensembl chr13:32,499,678...32,716,418
|
|
| G
|
Glipr1
|
GLI pathogenesis-related 1
|
multiple interactions increases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of GLIPR1 mRNA Progesterone results in increased expression of GLIPR1 mRNA
|
CTD |
PMID:20660070 PMID:21540246 |
|
NCBI chr 7:49,373,579...49,399,190
Ensembl chr 7:49,373,581...49,384,640
|
|
| G
|
Glis2
|
GLIS family zinc finger 2
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of GLIS2 mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr10:11,457,594...11,484,948
Ensembl chr10:11,457,792...11,477,995
|
|
| G
|
Glt1d1
|
glycosyltransferase 1 domain containing 1
|
increases expression
|
ISO
|
Progesterone results in increased expression of GLT1D1 mRNA
|
CTD |
PMID:21540246 |
|
NCBI chr12:34,611,942...34,685,591
Ensembl chr12:34,612,643...34,685,468
|
|
| G
|
Gltp
|
glycolipid transfer protein
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of GLTP mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr12:41,907,168...41,927,321
Ensembl chr12:47,567,770...47,587,946
|
|
| G
|
Glul
|
glutamate-ammonia ligase
|
increases expression
|
EXP
|
Progesterone results in increased expression of GLUL mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr13:68,519,500...68,585,554
Ensembl chr13:68,576,067...68,585,520
|
|
| G
|
Glyat
|
glycine-N-acyltransferase
|
multiple interactions increases expression
|
ISO
|
[Progesterone co-treated with Estradiol] results in increased expression of GLYAT mRNA Progesterone results in increased expression of GLYAT mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr 1:219,128,798...219,149,615
Ensembl chr 1:219,128,811...219,150,774
|
|
| G
|
Gmnn
|
geminin, DNA replication inhibitor
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of GMNN mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr17:40,301,771...40,310,054
Ensembl chr17:40,729,824...40,738,068
|
|
| G
|
Gmpr
|
guanosine monophosphate reductase
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of GMPR mRNA
|
CTD |
PMID:21540246 |
|
NCBI chr17:19,357,992...19,395,807
Ensembl chr17:19,357,992...19,431,655
|
|
| G
|
Gna11
|
G protein subunit alpha 11
|
affects expression
|
ISO
|
Progesterone affects the expression of GNA11 mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr 7:8,814,285...8,828,628
Ensembl chr 7:8,814,327...8,830,558
|
|
| G
|
Gnai3
|
G protein subunit alpha i3
|
multiple interactions decreases expression
|
ISO
|
CAV3 mutant form inhibits the reaction [Progesterone results in decreased expression of GNAI3 protein]; Cholesterol inhibits the reaction [Progesterone results in decreased expression of GNAI3 protein]
|
CTD |
PMID:19221014 |
|
NCBI chr 2:198,430,920...198,468,874
|
|
| G
|
Gnao1
|
G protein subunit alpha o1
|
increases expression
|
EXP
|
Progesterone results in increased expression of GNAO1 mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr19:11,040,788...11,198,437
Ensembl chr19:11,040,788...11,198,437
|
|
| G
|
Gnas
|
GNAS complex locus
|
increases expression multiple interactions
|
EXP ISO
|
Progesterone results in increased expression of GNAS protein CAV3 mutant form inhibits the reaction [Progesterone results in increased expression of GNAS protein]; Cholesterol inhibits the reaction [Progesterone results in increased expression of GNAS protein]
|
CTD |
PMID:15469997 PMID:19221014 |
|
NCBI chr 3:183,489,648...183,554,570
Ensembl chr 3:183,503,243...183,554,536
|
|
| G
|
Gng11
|
G protein subunit gamma 11
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of GNG11 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 4:32,977,681...32,983,121
Ensembl chr 4:32,977,664...32,984,438
|
|
| G
|
Gng12
|
G protein subunit gamma 12
|
affects expression
|
ISO
|
Progesterone affects the expression of GNG12 mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr 4:96,011,118...96,134,767
Ensembl chr 4:97,340,472...97,464,476
|
|
| G
|
Gng2
|
G protein subunit gamma 2
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of GNG2 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr15:4,365,222...4,466,060
Ensembl chr15:4,365,135...4,466,059
|
|
| G
|
Gng4
|
G protein subunit gamma 4
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of GNG4 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr17:93,432,791...93,481,709
Ensembl chr17:93,433,195...93,481,709
|
|
| G
|
Gnl2
|
G protein nucleolar 2
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of GNL2 mRNA
|
CTD |
PMID:21453500 |
|
NCBI chr 5:137,293,141...137,318,528
Ensembl chr 5:142,577,731...142,603,178
|
|
| G
|
Gnrh1
|
gonadotropin releasing hormone 1
|
multiple interactions decreases abundance
|
ISO
|
[Progesterone co-treated with Estradiol] results in increased secretion of GNRH1 protein; Tamoxifen inhibits the reaction [[Progesterone co-treated with Estradiol] results in increased secretion of GNRH1 protein] GNRH1 protein results in decreased abundance of Progesterone
|
CTD |
PMID:10566683 PMID:19261682 |
|
NCBI chr15:46,147,878...46,152,086
Ensembl chr15:46,148,301...46,148,977 Ensembl chr15:46,148,301...46,148,977
|
|
| G
|
Gnrhr
|
gonadotropin releasing hormone receptor
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] inhibits the reaction [Triptorelin Pamoate affects the expression of GNRHR mRNA]; [Estradiol co-treated with Progesterone] results in decreased expression of GNRHR mRNA; Progesterone promotes the reaction [Triptorelin Pamoate affects the expression of GNRHR mRNA]
|
CTD |
PMID:17185802 |
|
NCBI chr14:21,856,871...21,874,861
|
|
| G
|
Got1
|
glutamic-oxaloacetic transaminase 1
|
increases expression multiple interactions
|
ISO EXP
|
Progesterone results in increased expression of GOT1 mRNA [Estradiol co-treated with Progesterone] results in increased expression of GOT1 mRNA
|
CTD |
PMID:18037150 PMID:20660070 PMID:20726854 |
|
NCBI chr 1:252,306,541...252,337,622
Ensembl chr 1:252,284,434...252,329,871
|
|
| G
|
Gp1bb
|
glycoprotein Ib platelet subunit beta
|
decreases expression
|
EXP
|
Progesterone results in decreased expression of GP1BB mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr11:95,882,561...95,883,738
|
|
| G
|
Gpaa1
|
glycosylphosphatidylinositol anchor attachment 1
|
affects expression
|
ISO
|
Progesterone affects the expression of GPAA1 mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr 7:109,932,556...109,936,139
Ensembl chr 7:109,932,544...109,936,138
|
|
| G
|
Gpd1
|
glycerol-3-phosphate dehydrogenase 1
|
affects expression
|
ISO
|
Progesterone affects the expression of GPD1 mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr 7:130,842,526...130,851,530
Ensembl chr 7:132,721,915...132,730,368
|
|
| G
|
Gpd1l
|
glycerol-3-phosphate dehydrogenase 1 like
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of GPD1L mRNA; [Progesterone co-treated with Estradiol] results in increased expression of GPD1L mRNA
|
CTD |
PMID:17404688 PMID:20660070 |
|
NCBI chr 8:114,591,103...114,620,771
Ensembl chr 8:123,466,667...123,498,908
|
|
| G
|
Gpd2
|
glycerol-3-phosphate dehydrogenase 2
|
increases expression
|
ISO
|
Progesterone results in increased expression of GPD2 mRNA
|
CTD |
PMID:19693291 |
|
NCBI chr 3:62,209,432...62,346,590
Ensembl chr 3:62,210,814...62,346,593
|
|
| G
|
Gpr149
|
G protein-coupled receptor 149
|
decreases expression
|
EXP
|
Progesterone results in decreased expression of GPR149 mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr 2:146,909,710...146,981,924
Ensembl chr 2:149,059,336...149,130,785
|
|
| G
|
Gpr155
|
G protein-coupled receptor 155
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of GPR155 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 3:78,623,931...78,677,803
Ensembl chr 3:78,607,976...78,677,803
|
|
| G
|
Gpr17
|
G protein-coupled receptor 17
|
decreases expression multiple interactions
|
ISO
|
Progesterone results in decreased expression of GPR17 mRNA [Progesterone co-treated with Estradiol] results in decreased expression of GPR17 mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr18:23,850,460...23,857,381
Ensembl chr18:23,850,107...23,857,702
|
|
| G
|
Gprc5a
|
G protein-coupled receptor, class C, group 5, member A
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of GPRC5A mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 4:167,903,542...167,922,276
Ensembl chr 4:169,634,748...169,653,625
|
|
| G
|
Gprc5b
|
G protein-coupled receptor, class C, group 5, member B
|
multiple interactions increases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of GPRC5B mRNA Progesterone results in increased expression of GPRC5B mRNA
|
CTD |
PMID:20660070 PMID:20864642 |
|
NCBI chr 1:182,748,247...182,772,711
Ensembl chr 1:182,748,247...182,772,757
|
|
| G
|
Gprc5c
|
G protein-coupled receptor, class C, group 5, member C
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of GPRC5C mRNA
|
CTD |
PMID:19693291 |
|
NCBI chr10:99,886,900...99,908,928
Ensembl chr10:100,383,631...100,426,962
|
|
| G
|
Gpt
|
glutamic--pyruvic transaminase
|
multiple interactions
|
EXP
|
[Progesterone co-treated with Estradiol] results in decreased activity of GPT protein
|
CTD |
PMID:15820610 |
|
NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:110,296,206...110,300,160
|
|
| G
|
Gpx2
|
glutathione peroxidase 2
|
multiple interactions affects expression decreases expression
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of GPX2 mRNA Progesterone affects the expression of GPX2 mRNA Progesterone results in decreased expression of GPX2 mRNA
|
CTD |
PMID:17251523 PMID:17404688 |
|
NCBI chr 6:101,226,745...101,230,033
Ensembl chr 6:101,226,745...101,230,862
|
|
| G
|
Gpx3
|
glutathione peroxidase 3
|
affects expression multiple interactions increases expression
|
ISO EXP
|
Progesterone affects the expression of GPX3 mRNA [Estradiol co-treated with Progesterone] results in increased expression of GPX3 mRNA Progesterone results in increased expression of GPX3 mRNA
|
CTD |
PMID:17251523 PMID:18556351 PMID:19693291 PMID:20726854 PMID:20864642 |
|
NCBI chr10:39,028,624...39,036,695
Ensembl chr10:39,529,448...39,537,405
|
|
| G
|
Grb10
|
growth factor receptor bound protein 10
|
increases expression
|
ISO
|
Progesterone results in increased expression of GRB10 mRNA
|
CTD |
PMID:21795739 |
|
NCBI chr14:90,708,653...90,816,399
Ensembl chr14:90,708,653...90,816,387
|
|
| G
|
Grb2
|
growth factor receptor bound protein 2
|
multiple interactions
|
EXP
|
[Estradiol co-treated with Progesterone co-treated with Methylnitrosourea] results in increased expression of GRB2 mRNA; [Estradiol co-treated with Progesterone co-treated with Methylnitrosourea] results in increased expression of GRB2 protein
|
CTD |
PMID:22465879 |
|
NCBI chr10:100,881,404...100,949,193
Ensembl chr10:101,380,356...101,448,138
|
|
| G
|
Greb1
|
growth regulating estrogen receptor binding 1
|
multiple interactions decreases expression increases expression
|
ISO
|
[Progesterone co-treated with Estradiol] results in increased expression of GREB1 mRNA; ESR1 protein affects the reaction [Progesterone results in increased expression of GREB1 mRNA]; Fulvestrant inhibits the reaction [Progesterone results in increased expression of GREB1 mRNA] Progesterone results in decreased expression of GREB1 mRNA
|
CTD |
PMID:17404688 PMID:20864642 PMID:22238285 PMID:33405908 |
|
NCBI chr 6:45,169,289...45,321,973
Ensembl chr 6:45,169,289...45,291,126
|
|
| G
|
Grem1
|
gremlin 1, DAN family BMP antagonist
|
multiple interactions decreases expression
|
ISO EXP
|
[Progesterone co-treated with Estradiol] results in decreased expression of GREM1 mRNA Progesterone results in decreased expression of GREM1 mRNA
|
CTD |
PMID:17404688 PMID:20726854 PMID:20864642 |
|
NCBI chr 3:100,512,317...100,524,001
Ensembl chr 3:120,966,623...120,979,089
|
|
| G
|
Grhl1
|
grainyhead-like transcription factor 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of GRHL1 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 6:46,935,947...46,986,126
Ensembl chr 6:46,935,967...46,980,264
|
|
| G
|
Grhl3
|
grainyhead-like transcription factor 3
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of GRHL3 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 5:153,057,760...153,089,890
Ensembl chr 5:153,057,760...153,089,890
|
|
| G
|
Gria1
|
glutamate ionotropic receptor AMPA type subunit 1
|
increases expression multiple interactions
|
ISO
|
Progesterone results in increased expression of GRIA1 mRNA [Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with Estradiol] results in decreased expression of GRIA1 mRNA; NR3C1 protein inhibits the reaction [[Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with Estradiol] results in decreased expression of GRIA1 mRNA]; NR3C2 protein promotes the reaction [[Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with Estradiol] results in decreased expression of GRIA1 mRNA]
|
CTD |
PMID:21795739 PMID:23275455 |
|
NCBI chr10:41,710,540...42,030,105
Ensembl chr10:41,711,080...42,030,309
|
|
| G
|
Grp
|
gastrin releasing peptide
|
increases expression
|
ISO
|
Progesterone results in increased expression of GRP mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr18:61,658,655...61,672,037
Ensembl chr18:61,658,250...61,672,037
|
|
| G
|
Grpel1
|
GrpE-like 1, mitochondrial
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of GRPEL1 mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr14:74,292,023...74,298,243
Ensembl chr14:78,517,052...78,522,861
|
|
| G
|
Grwd1
|
glutamate-rich WD repeat containing 1
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of GRWD1 mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr 1:96,301,260...96,306,962
Ensembl chr 1:105,437,709...105,443,825
|
|
| G
|
Gsdme
|
gasdermin E
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of GSDME mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 4:80,590,344...80,651,943
Ensembl chr 4:80,588,614...80,641,525
|
|
| G
|
Gsk3b
|
glycogen synthase kinase 3 beta
|
multiple interactions decreases expression decreases phosphorylation increases phosphorylation
|
ISO EXP
|
Mifepristone inhibits the reaction [Progesterone results in increased phosphorylation of GSK3B protein] Progesterone results in decreased expression of GSK3B mRNA; Progesterone results in decreased expression of GSK3B protein Progesterone results in decreased phosphorylation of GSK3B protein Estradiol inhibits the reaction [Progesterone results in decreased expression of GSK3B mRNA] Progesterone inhibits the reaction [Estradiol results in increased phosphorylation of GSK3B protein]
|
CTD |
PMID:15845746 PMID:16882987 PMID:17170212 PMID:17443805 |
|
NCBI chr11:76,004,502...76,154,665
Ensembl chr11:76,009,507...76,153,249
|
|
| G
|
Gsn
|
gelsolin
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of GSN mRNA
|
CTD |
PMID:18556351 |
|
NCBI chr 3:18,585,166...18,638,404
Ensembl chr 3:38,982,671...39,035,850
|
|
| G
|
Gsta1
|
glutathione S-transferase alpha 1
|
increases chemical synthesis increases expression
|
ISO EXP
|
GSTA1 protein results in increased chemical synthesis of Progesterone Progesterone results in increased expression of GSTA1 mRNA
|
CTD |
PMID:20726854 PMID:23650189 |
|
NCBI chr 9:31,199,887...31,216,606
Ensembl chr 9:31,199,888...31,211,528
|
|
| G
|
Gsta2
|
glutathione S-transferase alpha 2
|
multiple interactions increases expression
|
EXP
|
[Progesterone co-treated with Estradiol] affects the expression of GSTA2 mRNA Progesterone results in increased expression of GSTA2 mRNA
|
CTD |
PMID:11502894 PMID:24777823 |
|
NCBI chr 8:88,064,829...88,077,168
Ensembl chr 8:88,064,616...88,077,092
|
|
| G
|
Gstk1
|
glutathione S-transferase kappa 1
|
increases expression
|
EXP
|
Progesterone results in increased expression of GSTK1 mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr 4:71,118,979...71,123,298
Ensembl chr 4:72,085,531...72,089,927
|
|
| G
|
Gstm2
|
glutathione S-transferase mu 2
|
affects expression
|
ISO
|
Progesterone affects the expression of GSTM2 mRNA; Progesterone affects the expression of GSTM5 mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr 2:198,312,179...198,316,962
|
|
| G
|
Gsto1
|
glutathione S-transferase omega 1
|
increases expression
|
ISO
|
Progesterone results in increased expression of GSTO1 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 1:256,662,377...256,672,515
Ensembl chr 1:256,662,531...256,676,167
|
|
| G
|
Gstt1
|
glutathione S-transferase theta 1
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of GSTT1 mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr20:12,856,068...12,873,020
Ensembl chr20:12,856,083...12,873,019
|
|
| G
|
Gstt2
|
glutathione S-transferase theta 2
|
increases expression
|
EXP
|
Progesterone results in increased expression of GSTT2 mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr20:12,819,617...12,823,288
Ensembl chr20:12,818,540...12,822,718
|
|
| G
|
Gsx1
|
GS homeobox 1
|
increases expression
|
ISO
|
Progesterone results in increased expression of GSX1 mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr12:7,880,663...7,882,947
Ensembl chr12:12,994,588...12,996,874
|
|
| G
|
Gtf2ird1
|
GTF2I repeat domain containing 1
|
increases expression
|
ISO
|
Progesterone results in increased expression of GTF2IRD1 mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr12:22,254,113...22,361,052
Ensembl chr12:27,890,675...27,997,494
|
|
| G
|
Gtse1
|
G-2 and S-phase expressed 1
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of GTSE1 mRNA
|
CTD |
PMID:21795739 |
|
NCBI chr 7:116,949,997...116,966,826
Ensembl chr 7:118,829,903...118,846,661
|
|
| G
|
Guca2b
|
guanylate cyclase activator 2B
|
affects expression
|
ISO
|
Progesterone affects the expression of GUCA2B mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr 5:138,532,160...138,534,210
Ensembl chr 5:138,532,178...138,534,235
|
|
| G
|
Gucy1a1
|
guanylate cyclase 1 soluble subunit alpha 1
|
decreases expression
|
EXP
|
Progesterone results in decreased expression of GUCY1A1 mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr 2:169,716,684...169,780,360
Ensembl chr 2:169,716,709...169,779,737
|
|
| G
|
Gyg1
|
glycogenin 1
|
increases expression
|
EXP
|
Progesterone results in increased expression of GYG1 mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr 2:104,540,927...104,583,038
Ensembl chr 2:104,540,533...104,582,818
|
|
| G
|
Gzmb
|
granzyme B
|
affects expression increases expression
|
ISO EXP
|
Progesterone affects the expression of GZMB mRNA Progesterone results in increased expression of GZMB mRNA
|
CTD |
PMID:17251523 PMID:21770760 |
|
NCBI chr15:34,459,007...34,462,469
Ensembl chr15:34,459,007...34,462,469
|
|
| G
|
H19
|
H19 imprinted maternally expressed transcript
|
affects expression
|
ISO
|
Progesterone affects the expression of H19 mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr 1:197,730,698...197,733,374
|
|
| G
|
H1f2
|
H1.2 linker histone, cluster member
|
increases expression multiple interactions
|
ISO
|
Progesterone results in increased expression of H1F2 mRNA [Progesterone co-treated with Estradiol] results in increased expression of H1-2 mRNA
|
CTD |
PMID:17404688 PMID:22238285 |
|
NCBI chr17:41,818,962...41,820,453
Ensembl chr17:41,779,051...41,822,317
|
|
| G
|
H1f5
|
H1.5 linker histone, cluster member
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of H1F5 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr17:47,421,875...47,422,905
Ensembl chr17:47,421,843...47,477,387
|
|
| G
|
H2ac18
|
H2A clustered histone 18
|
increases expression
|
ISO
|
Progesterone results in increased expression of H2AC18 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 2:183,808,398...183,808,992
|
|
| G
|
H2az1
|
H2A.Z variant histone 1
|
decreases expression
|
EXP
|
Progesterone results in decreased expression of H2AZ1 mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr 2:229,026,464...229,031,411
Ensembl chr 2:229,028,843...229,031,411
|
|
| G
|
H2az2
|
H2A.Z variant histone 2
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of H2AZ2 mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr14:81,293,304...81,312,209
Ensembl chr14:85,507,228...85,526,207 Ensembl chr16:85,507,228...85,526,207
|
|
| G
|
H2bc14
|
H2B clustered histone 14
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in increased expression of H2BC5 mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr17:42,792,887...42,793,268
|
|
| G
|
H2bc4
|
H2B clustered histone 4
|
increases expression
|
ISO
|
Progesterone results in increased expression of H2BC4 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr17:47,388,085...47,392,349
Ensembl chr17:47,404,375...47,419,020
|
|
| G
|
H2bc9
|
H2B clustered histone 9
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in increased expression of H2BC9 mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr17:42,470,593...42,478,590
|
|
| G
|
Habp2
|
hyaluronan binding protein 2
|
multiple interactions increases expression
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of HABP2 mRNA Progesterone results in increased expression of HABP2 mRNA
|
CTD |
PMID:17404688 PMID:21540246 |
|
NCBI chr 1:255,315,870...255,350,161
Ensembl chr 1:265,303,172...265,355,374
|
|
| G
|
Hacd1
|
3-hydroxyacyl-CoA dehydratase 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of HACD1 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr17:81,992,284...82,014,676
Ensembl chr17:81,992,292...82,014,592
|
|
| G
|
Hacd4
|
3-hydroxyacyl-CoA dehydratase 4
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of HACD4 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 5:107,935,514...107,961,271
Ensembl chr 5:107,934,937...107,962,836
|
|
| G
|
Hadh
|
hydroxyacyl-CoA dehydrogenase
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of HADH mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 2:222,462,049...222,504,446
Ensembl chr 2:222,462,049...222,504,446
|
|
| G
|
Hand2
|
heart and neural crest derivatives expressed 2
|
multiple interactions increases expression
|
ISO
|
[Progesterone co-treated with Estradiol] results in increased expression of HAND2 mRNA Progesterone results in increased expression of HAND2 mRNA [Estradiol co-treated with Progesterone] results in increased expression of HAND2 protein; [Progesterone co-treated with S-Adenosylmethionine] results in increased methylation of HAND2 promoter; S-Adenosylmethionine inhibits the reaction [Progesterone results in increased expression of HAND2 mRNA]
|
CTD |
PMID:17404688 PMID:18070364 PMID:20864642 PMID:25210133 PMID:30892605 |
|
NCBI chr16:32,917,448...32,920,791
Ensembl chr16:37,928,145...37,931,488
|
|
| G
|
Hapln1
|
hyaluronan and proteoglycan link protein 1
|
decreases expression increases expression
|
ISO
|
Progesterone results in decreased expression of HAPLN1 mRNA Progesterone results in increased expression of HAPLN1 mRNA
|
CTD |
PMID:21540246 PMID:21795739 |
|
NCBI chr 2:22,366,967...22,431,709
Ensembl chr 2:22,366,967...22,429,098
|
|
| G
|
Has1
|
hyaluronan synthase 1
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of HAS1 mRNA
|
CTD |
PMID:20226447 |
|
NCBI chr 1:67,366,460...67,378,686
Ensembl chr 1:67,366,460...67,378,444
|
|
| G
|
Has3
|
hyaluronan synthase 3
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of HAS3 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr19:34,768,421...34,782,170
|
|
| G
|
Hba-a1
|
hemoglobin alpha, adult chain 1
|
affects expression
|
ISO
|
Progesterone affects the expression of HBA-A1 mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr10:15,337,265...15,338,121
Ensembl chr10:15,841,763...15,842,603
|
|
| G
|
Hba-a2
|
hemoglobin alpha, adult chain 2
|
multiple interactions increases expression
|
ISO
|
[Progesterone co-treated with Estradiol] results in increased expression of HBA1 mRNA Progesterone results in increased expression of HBA1 mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr10:15,828,291...15,829,138
Ensembl chr10:15,828,377...15,829,141
|
|
| G
|
Hba-a3
|
hemoglobin alpha, adult chain 3
|
multiple interactions increases expression
|
ISO
|
[Progesterone co-treated with Estradiol] results in increased expression of HBA2 mRNA Progesterone results in increased expression of HBA2 mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr10:15,816,099...15,816,943
Ensembl chr10:15,816,096...15,817,167
|
|
| G
|
Hbb
|
hemoglobin subunit beta
|
multiple interactions affects expression increases expression
|
ISO
|
[Progesterone co-treated with Estradiol] results in increased expression of HBB mRNA Progesterone affects the expression of HBB-B1 mRNA Progesterone results in increased expression of HBB mRNA
|
CTD |
PMID:17251523 PMID:17404688 PMID:18070364 |
|
NCBI chr 1:167,662,310...167,663,721
Ensembl chr 1:167,630,245...167,663,873
|
|
| G
|
Hbb-b1
|
hemoglobin, beta adult major chain
|
multiple interactions increases expression
|
ISO
|
[Progesterone co-treated with Estradiol] results in increased expression of HBD mRNA Progesterone results in increased expression of HBD mRNA
|
CTD |
PMID:17404688 PMID:18070364 |
|
NCBI chr 1:158,224,175...158,231,675
|
|
| G
|
Hbb-b2
|
hemoglobin, beta adult minor chain
|
affects expression
|
ISO
|
Progesterone affects the expression of HBB-B2 mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr 1:158,243,696...158,245,076
|
|
| G
|
Hbg1
|
hemoglobin subunit gamma 1
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in increased expression of HBG1 mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr 1:158,271,871...158,273,426
Ensembl chr 1:167,683,760...167,706,139
|
|
| G
|
Hbp1
|
HMG-box transcription factor 1
|
increases expression multiple interactions
|
ISO
|
Progesterone results in increased expression of HBP1 mRNA [Estradiol co-treated with Progesterone] results in increased expression of HBP1 mRNA
|
CTD |
PMID:18070364 PMID:18556351 |
|
NCBI chr 6:48,529,633...48,555,775
Ensembl chr 6:54,256,864...54,283,366
|
|
| G
|
Hbs1l
|
HBS1-like translational GTPase
|
increases expression
|
ISO
|
Progesterone results in increased expression of HBS1L mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr 1:16,092,529...16,170,082
Ensembl chr 1:17,912,070...17,989,646
|
|
| G
|
Hcls1
|
hematopoietic cell specific Lyn substrate 1
|
increases expression
|
ISO
|
Progesterone results in increased expression of HCLS1 mRNA
|
CTD |
PMID:21540246 |
|
NCBI chr11:77,322,873...77,346,333
Ensembl chr11:77,322,873...77,346,387
|
|
| G
|
Hcrt
|
hypocretin neuropeptide precursor
|
decreases secretion
|
EXP
|
HCRT protein results in decreased secretion of Progesterone
|
CTD |
PMID:22749989 |
|
NCBI chr10:85,689,979...85,691,214
Ensembl chr10:86,189,775...86,191,524
|
|
| G
|
Hdac1
|
histone deacetylase 1
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of HDAC1 mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr 5:147,138,328...147,165,387
Ensembl chr 5:147,138,156...147,165,387
|
|
| G
|
Hdc
|
histidine decarboxylase
|
affects expression
|
ISO
|
Progesterone affects the expression of HDC; Progesterone affects the expression of HDC mRNA
|
CTD |
PMID:16794005 PMID:17251523 |
|
NCBI chr 3:134,300,628...134,318,704
Ensembl chr 3:134,300,632...134,318,711
|
|
| G
|
Heg1
|
heart development protein with EGF-like domains 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of HEG1 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr11:67,006,954...67,095,020
Ensembl chr11:80,512,096...80,600,092
|
|
| G
|
Hells
|
helicase, lymphoid specific
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of HELLS mRNA
|
CTD |
PMID:16966611 PMID:21795739 PMID:22238285 |
|
NCBI chr 1:246,113,580...246,159,230
Ensembl chr 1:246,114,096...246,159,228
|
|
| G
|
Heph
|
hephaestin
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of HEPH mRNA
|
CTD |
PMID:19693291 |
|
NCBI chr X:61,151,131...61,402,980
Ensembl chr X:65,305,773...65,412,453
|
|
| G
|
Herpud1
|
homocysteine inducible ER protein with ubiquitin like domain 1
|
increases expression
|
ISO
|
Progesterone results in increased expression of HERPUD1 mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr19:10,604,360...10,624,168
Ensembl chr19:10,604,362...10,624,081
|
|
| G
|
Hes1
|
hes family bHLH transcription factor 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of HES1 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr11:84,210,632...84,213,045
Ensembl chr11:84,210,633...84,213,061
|
|
| G
|
Hes5
|
hes family bHLH transcription factor 5
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of HES5 mRNA
|
CTD |
PMID:21540246 |
|
NCBI chr 5:170,804,511...170,807,988
Ensembl chr 5:170,803,940...170,806,021
|
|
| G
|
Hgd
|
homogentisate 1, 2-dioxygenase
|
multiple interactions decreases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of HGD mRNA Progesterone results in decreased expression of HGD mRNA
|
CTD |
PMID:20660070 PMID:21540246 |
|
NCBI chr11:76,592,202...76,643,776
Ensembl chr11:76,592,204...76,643,767
|
|
| G
|
Hgf
|
hepatocyte growth factor
|
multiple interactions increases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of HGF mRNA; [Progesterone co-treated with Estradiol] results in decreased expression of HGF mRNA Progesterone results in increased expression of HGF mRNA
|
CTD |
PMID:17404688 PMID:20660070 PMID:22238285 |
|
NCBI chr 4:19,628,902...19,700,467
Ensembl chr 4:19,632,267...19,700,851
|
|
| G
|
Hibadh
|
3-hydroxyisobutyrate dehydrogenase
|
increases expression
|
EXP
|
Progesterone results in increased expression of HIBADH mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr 4:82,979,759...83,077,819
Ensembl chr 4:82,979,765...83,111,242
|
|
| G
|
Hibch
|
3-hydroxyisobutyryl-CoA hydrolase
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of HIBCH mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 9:56,082,082...56,161,796
Ensembl chr 9:56,082,091...56,161,886
|
|
| G
|
Hic1
|
HIC ZBTB transcriptional repressor 1
|
multiple interactions increases expression
|
ISO
|
[Progesterone co-treated with TGFB1 protein] results in increased expression of HIC1 mRNA Progesterone results in increased expression of HIC1 mRNA
|
CTD |
PMID:21768398 |
|
NCBI chr10:60,512,855...60,517,812
Ensembl chr10:60,500,565...60,523,448
|
|
| G
|
Hif1a
|
hypoxia inducible factor 1 subunit alpha
|
increases expression
|
ISO
|
Progesterone results in increased expression of HIF1A
|
CTD |
PMID:15845616 |
|
NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:98,359,910...98,405,323
|
|
| G
|
Hip1r
|
huntingtin interacting protein 1 related
|
affects expression
|
ISO
|
Progesterone affects the expression of HIP1R mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr12:38,251,085...38,279,756
Ensembl chr12:38,251,086...38,279,654
|
|
| G
|
Hipk2
|
homeodomain interacting protein kinase 2
|
decreases expression multiple interactions
|
ISO
|
Progesterone results in decreased expression of HIPK2 mRNA [Estradiol co-treated with Progesterone] results in decreased expression of HIPK2 mRNA
|
CTD |
PMID:18070364 PMID:20660070 |
|
NCBI chr 4:67,439,327...67,619,223
Ensembl chr 4:68,369,099...68,586,108
|
|
| G
|
Hjurp
|
Holliday junction recognition protein
|
increases expression
|
ISO
|
Progesterone results in increased expression of HJURP mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr 9:96,301,183...96,315,587
Ensembl chr 9:96,302,530...96,315,657
|
|
| G
|
Hmcn1
|
hemicentin 1
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of HMCN1 mRNA
|
CTD |
PMID:21795739 |
|
NCBI chr13:65,165,532...65,634,681
Ensembl chr13:65,165,532...65,634,519
|
|
| G
|
Hmga1
|
high mobility group AT-hook 1
|
multiple interactions decreases expression
|
ISO
|
4-(2-aminoethyl)benzenesulfonylfluoride inhibits the reaction [[Estradiol co-treated with Progesterone] results in decreased expression of HMGA1 mRNA]; [Estradiol co-treated with Progesterone] results in decreased expression of HMGA1 mRNA; N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide inhibits the reaction [[Estradiol co-treated with Progesterone] results in decreased expression of HMGA1 mRNA]; pepstatin inhibits the reaction [[Estradiol co-treated with Progesterone] results in decreased expression of HMGA1 mRNA] Progesterone results in decreased expression of HMGA1 mRNA
|
CTD |
PMID:17404688 PMID:20660070 PMID:22238285 |
|
NCBI chr20:5,611,088...5,618,755
Ensembl chr20:5,613,471...5,620,593
|
|
| G
|
Hmga2
|
high mobility group AT-hook 2
|
multiple interactions decreases expression
|
ISO
|
NCOA2 protein affects the reaction [Progesterone results in decreased expression of HMGA2 mRNA]
|
CTD |
PMID:17556502 |
|
NCBI chr 7:55,877,145...55,998,813
Ensembl chr 7:57,765,675...57,880,341
|
|
| G
|
Hmgb1
|
high mobility group box 1
|
multiple interactions
|
ISO
|
Progesterone inhibits the reaction [[Lipopolysaccharides co-treated with HMGB1 protein] results in increased expression of CCL2 protein]; Progesterone inhibits the reaction [[Lipopolysaccharides co-treated with HMGB1 protein] results in increased expression of CXCL8 protein]; Progesterone inhibits the reaction [[Lipopolysaccharides co-treated with HMGB1 protein] results in increased expression of IL6 protein]; Progesterone inhibits the reaction [[Lipopolysaccharides co-treated with HMGB1 protein] results in increased expression of TLR4 mRNA]
|
CTD |
PMID:22014880 |
|
NCBI chr12:11,009,236...11,015,941
Ensembl chr16:39,039,050...39,041,327 Ensembl chr12:39,039,050...39,041,327
|
|
| G
|
Hmgb2
|
high mobility group box 2
|
increases expression decreases expression
|
ISO EXP
|
Progesterone results in increased expression of HMGB2 mRNA Progesterone results in decreased expression of HMGB2 mRNA
|
CTD |
PMID:18070364 PMID:20726854 |
|
NCBI chr16:37,721,374...37,723,950
Ensembl chr16:37,721,379...37,723,860
|
|
| G
|
Hmgcl
|
3-hydroxy-3-methylglutaryl-CoA lyase
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of HMGCL mRNA
|
CTD |
PMID:18556351 |
|
NCBI chr 5:153,461,738...153,475,552
Ensembl chr 5:153,461,769...153,475,604
|
|
| G
|
Hmgcr
|
3-hydroxy-3-methylglutaryl-CoA reductase
|
increases expression
|
ISO
|
Progesterone results in increased expression of HMGCR mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr 2:29,732,163...29,754,276
Ensembl chr 2:29,720,553...29,754,533
|
|
| G
|
Hmgcs1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1
|
increases expression
|
ISO
|
Progesterone results in increased expression of HMGCS1 mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr 2:53,379,457...53,399,807
Ensembl chr 2:53,382,643...53,399,802
|
|
| G
|
Hmgcs2
|
3-hydroxy-3-methylglutaryl-CoA synthase 2
|
increases expression
|
EXP
|
Progesterone results in increased expression of HMGCS2 mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr 2:188,564,348...188,590,872
Ensembl chr 2:188,547,767...188,592,242
|
|
| G
|
Hmgn3
|
high mobility group nucleosomal binding domain 3
|
increases expression
|
ISO
|
Progesterone results in increased expression of HMGN3 mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr 8:84,022,493...84,059,329
|
|
| G
|
Hmmr
|
hyaluronan-mediated motility receptor
|
increases expression decreases expression
|
ISO
|
Progesterone results in increased expression of HMMR mRNA Progesterone results in decreased expression of HMMR mRNA
|
CTD |
PMID:18070364 PMID:21795739 |
|
NCBI chr10:25,635,249...25,665,389
Ensembl chr10:25,635,915...25,665,390
|
|
| G
|
Hmox1
|
heme oxygenase 1
|
multiple interactions increases expression affects expression
|
ISO EXP
|
[Progesterone co-treated with Estradiol] results in decreased expression of HMOX1 mRNA Progesterone results in increased expression of HMOX1 mRNA HMOX1 protein inhibits the reaction [POMC protein results in increased abundance of Progesterone] Progesterone affects the expression of HMOX1 mRNA
|
CTD |
PMID:17251523 PMID:17404688 PMID:18070364 PMID:19489000 PMID:21770760 |
|
NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818
|
|
| G
|
Hnf4a
|
hepatocyte nuclear factor 4, alpha
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime promotes the reaction [[NR1I3 protein co-treated with FOXO1 protein co-treated with HNF4A protein co-treated with NCOA1 protein] binds to CYP2C9 promoter]]; Progesterone inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime inhibits the reaction [HNF4A protein binds to PCK1 promoter]]; Progesterone inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime promotes the reaction [[NR1I3 protein co-treated with FOXO1 protein co-treated with HNF4A protein co-treated with NCOA1 protein] binds to CYP2C9 promoter]]; Progesterone promotes the reaction [Estradiol inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime inhibits the reaction [HNF4A protein binds to PCK1 promoter]]]
|
CTD |
PMID:21768169 |
|
NCBI chr 3:172,606,220...172,667,758
Ensembl chr 3:172,606,220...172,667,758
|
|
| G
|
Hnrnpab
|
heterogeneous nuclear ribonucleoprotein A/B
|
decreases expression
|
EXP
|
Progesterone results in decreased expression of HNRNPAB mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr10:36,358,004...36,363,898
Ensembl chr10:36,358,006...36,364,307
|
|
| G
|
Hnrnph1
|
heterogeneous nuclear ribonucleoprotein H1
|
decreases expression
|
EXP
|
Progesterone results in decreased expression of HNRNPH1 mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr10:35,187,412...35,203,909
Ensembl chr10:35,193,890...35,203,906
|
|
| G
|
Homer2
|
homer scaffold protein 2
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of HOMER2 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 1:135,558,977...135,659,780
Ensembl chr 1:144,976,436...145,068,997
|
|
| G
|
Homer3
|
homer scaffold protein 3
|
decreases expression multiple interactions
|
ISO
|
Progesterone results in decreased expression of HOMER3 mRNA [Estradiol co-treated with Progesterone] results in decreased expression of HOMER3 mRNA
|
CTD |
PMID:19693291 PMID:20660070 |
|
NCBI chr16:19,132,177...19,142,739
Ensembl chr16:19,165,482...19,176,640
|
|
| G
|
Hopx
|
HOP homeobox
|
affects expression increases expression
|
ISO EXP
|
Progesterone affects the expression of HOPX mRNA Progesterone results in increased expression of HOPX mRNA
|
CTD |
PMID:17251523 PMID:20726854 |
|
NCBI chr14:31,410,235...31,437,189
Ensembl chr14:31,410,221...31,437,188
|
|
| G
|
Hoxa10
|
homeobox A10
|
decreases expression increases expression multiple interactions
|
ISO EXP
|
Progesterone results in decreased expression of HOXA10 mRNA Progesterone results in increased expression of HOXA10 [Estradiol co-treated with Progesterone] results in increased expression of HOXA10 mRNA; [Estradiol co-treated with Progesterone] results in increased expression of HOXA10 protein [Progesterone co-treated with Estrogens] results in decreased expression of HOXA10 mRNA; Copper promotes the reaction [[Progesterone co-treated with Estrogens] results in decreased expression of HOXA10 mRNA]; HOXA10 protein affects the reaction [Progesterone affects the localization of GABRP protein]; HOXA10 protein affects the reaction [Progesterone results in increased expression of GABRP mRNA]
|
CTD |
PMID:15845616 PMID:18037150 PMID:18653720 PMID:20103740 PMID:32004626 |
|
NCBI chr 4:81,331,591...81,340,878
Ensembl chr 4:82,662,204...82,665,922
|
|
| G
|
Hoxa11
|
homeobox A11
|
multiple interactions
|
ISO EXP
|
[Progesterone co-treated with Estradiol] results in decreased expression of HOXA11 mRNA [Estradiol co-treated with Progesterone co-treated with Corn Oil] results in increased expression of HOXA11 mRNA [Estradiol co-treated with Progesterone] results in increased expression of HOXA11 mRNA
|
CTD |
PMID:17404688 PMID:18653720 PMID:32186404 |
|
NCBI chr 4:81,342,527...81,346,189
Ensembl chr 4:82,673,140...82,676,844
|
|
| G
|
Hoxa11-as
|
HOXA11 antisense RNA
|
increases expression
|
ISO
|
Progesterone results in increased expression of HOXA11OS mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 4:81,346,416...81,350,190
Ensembl chr 4:82,677,028...82,680,791
|
|
| G
|
Hp
|
haptoglobin
|
affects expression multiple interactions
|
ISO
|
Progesterone affects the expression of HP mRNA [Estradiol co-treated with Progesterone] results in increased expression of HP mRNA
|
CTD |
PMID:17251523 PMID:20660070 |
|
NCBI chr19:54,449,151...54,453,701
Ensembl chr19:54,446,217...54,467,518
|
|
| G
|
Hras
|
HRas proto-oncogene, GTPase
|
increases expression
|
ISO
|
Progesterone results in increased expression of HRAS mRNA
|
CTD |
PMID:21549006 |
|
NCBI chr 1:205,712,625...205,729,406
Ensembl chr 1:205,725,975...205,729,590
|
|
| G
|
Hrk
|
harakiri, BCL2 interacting protein
|
increases expression
|
ISO
|
Progesterone results in increased expression of HRK mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr12:38,387,484...38,409,652
Ensembl chr12:44,048,402...44,070,561
|
|
| G
|
Hs3st3b1
|
heparan sulfate-glucosamine 3-sulfotransferase 3B1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of HS3ST3B1 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr10:49,060,693...49,093,185
Ensembl chr10:49,060,693...49,093,185
|
|
| G
|
Hs6st1
|
heparan sulfate 6-O-sulfotransferase 1
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of HS6ST1 mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr 9:45,779,402...45,818,583
Ensembl chr 9:45,779,019...45,818,582
|
|
| G
|
Hs6st2
|
heparan sulfate 6-O-sulfotransferase 2
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of HS6ST2 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr X:135,887,224...136,182,388
Ensembl chr X:135,888,472...136,182,353
|
|
| G
|
Hsd11b1
|
hydroxysteroid 11-beta dehydrogenase 1
|
affects expression multiple interactions increases expression
|
EXP ISO
|
Progesterone affects the expression of HSD11B1 mRNA; Progesterone affects the expression of HSD11B1 protein 4'-cyanobiphenyl-4-sulfonic acid (6-aminopyridin-2-yl)amide inhibits the reaction [[Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of HSD11B1 mRNA]; [Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with Estradiol] results in increased expression of HSD11B1 protein; [Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of HSD11B1 mRNA; Hydrocortisone promotes the reaction [[Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of HSD11B1 mRNA]; Progesterone inhibits the reaction [HSD11B1 protein results in increased reduction of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] Progesterone results in increased expression of HSD11B1 mRNA
|
CTD |
PMID:19208548 PMID:20726854 PMID:21795739 PMID:23275455 PMID:28257955 |
|
NCBI chr13:107,277,526...107,327,462
Ensembl chr13:107,257,239...107,327,432
|
|
| G
|
Hsd11b2
|
hydroxysteroid 11-beta dehydrogenase 2
|
multiple interactions decreases expression increases expression decreases activity
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of HSD11B2 mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Progesterone results in increased expression of HSD11B2 mRNA]; Masoprocol inhibits the reaction [Progesterone results in decreased activity of HSD11B2 protein]; Mifepristone inhibits the reaction [Progesterone results in decreased activity of HSD11B2 protein]; Mifepristone inhibits the reaction [Progesterone results in decreased expression of HSD11B2 mRNA]; Mifepristone inhibits the reaction [Progesterone results in decreased expression of HSD11B2 protein] Progesterone results in decreased expression of HSD11B2 mRNA; Progesterone results in decreased expression of HSD11B2 protein
|
CTD |
PMID:15857753 PMID:18032417 PMID:18070364 PMID:20660070 PMID:21540246 |
|
NCBI chr19:50,307,569...50,312,812
Ensembl chr19:50,307,569...50,312,812
|
|
| G
|
Hsd17b10
|
hydroxysteroid (17-beta) dehydrogenase 10
|
multiple interactions
|
ISO
|
[Progesterone co-treated with NAD] binds to HSD17B10 protein
|
CTD |
PMID:25526675 |
|
NCBI chr X:24,568,551...24,571,012
Ensembl chr X:24,568,551...24,574,681
|
|
| G
|
Hsd17b11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
increases expression
|
ISO
|
Progesterone results in increased expression of HSD17B11 mRNA
|
CTD |
PMID:18070364 PMID:20864642 |
|
NCBI chr14:5,997,893...6,047,816
Ensembl chr14:5,997,906...6,047,811
|
|
| G
|
Hsd17b2
|
hydroxysteroid (17-beta) dehydrogenase 2
|
multiple interactions decreases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of HSD17B2 mRNA; [Progesterone co-treated with Estradiol] results in increased expression of HSD17B2 mRNA Progesterone results in decreased expression of HSD17B2 mRNA; Progesterone results in decreased expression of HSD17B2 protein
|
CTD |
PMID:17404688 PMID:20660070 PMID:23183084 |
|
NCBI chr19:45,753,576...45,825,203
Ensembl chr19:62,662,098...62,733,943
|
|
| G
|
Hsd3b1
|
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
|
affects metabolic processing multiple interactions increases expression increases chemical synthesis
|
EXP ISO
|
HSD3B1 protein affects the metabolism of Progesterone [HSD3B2 protein results in increased metabolism of Pregnenolone] which results in increased abundance of Progesterone Progesterone results in increased expression of HSD3B1 protein HSD3B1 protein results in increased chemical synthesis of Progesterone
|
CTD |
PMID:15261307 PMID:16054388 PMID:21558439 PMID:31771930 |
|
NCBI chr 2:188,858,574...188,864,694
|
|
| G
|
Hsd3b2
|
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
|
multiple interactions
|
ISO EXP
|
[galaxolide results in decreased expression of [HSD3B2 co-treated with CYP21A2]] which results in decreased chemical synthesis of Progesterone [FSHB protein results in increased expression of HSD3B2 mRNA] which results in increased abundance of Progesterone; GH1 protein promotes the reaction [[FSHB protein results in increased expression of HSD3B2 mRNA] which results in increased abundance of Progesterone]; IGF1 protein promotes the reaction [[FSHB protein results in increased expression of HSD3B2 mRNA] which results in increased abundance of Progesterone]
|
CTD |
PMID:22067323 PMID:23084589 |
|
NCBI chr 2:186,095,897...186,105,354
Ensembl chr 2:188,784,614...188,790,569
|
|
| G
|
Hsp90aa1
|
heat shock protein 90 alpha family class A member 1
|
affects expression
|
ISO
|
Progesterone affects the expression of HSP90AA1 mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr 6:135,523,604...135,529,687
Ensembl chr 6:135,523,616...135,528,499
|
|
| G
|
Hsp90b1
|
heat shock protein 90 beta family member 1
|
affects expression
|
ISO
|
Progesterone affects the expression of HSP90B1 mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr 7:22,997,962...23,012,293
Ensembl chr 7:22,997,962...23,012,293
|
|
| G
|
Hspa1a
|
heat shock protein family A (Hsp70) member 1A
|
affects expression increases expression
|
EXP ISO
|
Progesterone affects the expression of HSPA1A protein Progesterone results in increased expression of HSPA1A mRNA
|
CTD |
PMID:16797538 PMID:21549006 |
|
NCBI chr20:3,875,411...3,877,866
Ensembl chr20:3,855,780...3,877,979
|
|
| G
|
Hspa1b
|
heat shock protein family A (Hsp70) member 1B
|
increases expression affects expression
|
ISO
|
Progesterone results in increased expression of HSPA1B mRNA Progesterone affects the expression of HSPA1B mRNA
|
CTD |
PMID:17251523 PMID:18037150 |
|
NCBI chr20:3,859,756...3,863,800
Ensembl chr20:3,855,780...3,877,979
|
|
| G
|
Hspa4
|
heat shock protein family A (Hsp70) member 4
|
increases expression
|
EXP
|
Progesterone results in increased expression of HSPA4 mRNA
|
CTD |
PMID:16376865 |
|
NCBI chr10:37,908,866...37,951,994
Ensembl chr10:37,908,866...37,949,835
|
|
| G
|
Hspa4l
|
heat shock protein family A (Hsp70) member 4 like
|
affects expression
|
ISO
|
Progesterone affects the expression of HSPA4L mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr 2:125,668,346...125,726,404
Ensembl chr 2:125,668,236...125,720,986
|
|
| G
|
Hspa5
|
heat shock protein family A (Hsp70) member 5
|
affects expression
|
ISO
|
Progesterone affects the expression of HSPA5 mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr 3:38,453,016...38,457,475
Ensembl chr 3:38,453,041...38,458,790
|
|
| G
|
Hspa6l-ps1
|
heat shock protein family A (Hsp70) member 6 like, pseudogene 1
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in increased expression of HSPA6 mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr13:83,273,176...83,274,317
|
|
| G
|
Hspa8
|
heat shock protein family A (Hsp70) member 8
|
multiple interactions
|
EXP
|
[estradiol 3-benzoate co-treated with Progesterone] results in increased expression of HSPA8 mRNA; Progesterone promotes the reaction [estradiol 3-benzoate results in increased expression of HSPA8 mRNA]
|
CTD |
PMID:9990085 |
|
NCBI chr 8:50,080,514...50,084,376
Ensembl chr 8:50,080,199...50,084,372
|
|
| G
|
Hspb1
|
heat shock protein family B (small) member 1
|
increases expression
|
EXP
|
Progesterone results in increased expression of HSPB1 mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr12:26,430,640...26,432,301
Ensembl chr12:26,430,640...26,432,301
|
|
| G
|
Hspb6
|
heat shock protein family B (small) member 6
|
increases expression
|
EXP
|
Progesterone results in increased expression of HSPB6 mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr 1:85,806,898...85,809,072
Ensembl chr 1:94,933,543...94,936,512
|
|
| G
|
Hspb8
|
heat shock protein family B (small) member 8
|
increases expression multiple interactions
|
EXP ISO
|
Progesterone results in increased expression of HSPB8 mRNA [Estradiol co-treated with Progesterone] results in increased expression of HSPB8 mRNA
|
CTD |
PMID:20660070 PMID:20726854 |
|
NCBI chr12:45,835,899...45,866,449
Ensembl chr12:45,837,066...45,851,937
|
|
| G
|
Htr2a
|
5-hydroxytryptamine receptor 2A
|
increases expression
|
ISO EXP
|
Progesterone results in increased expression of HTR2A mRNA
|
CTD |
PMID:20726854 PMID:21540246 |
|
NCBI chr15:56,360,647...56,428,703
Ensembl chr15:56,359,596...56,431,619
|
|
| G
|
Htr2b
|
5-hydroxytryptamine receptor 2B
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of HTR2B mRNA
|
CTD |
PMID:21795739 |
|
NCBI chr 9:94,184,442...94,206,851
Ensembl chr 9:94,190,109...94,204,087
|
|
| G
|
Hyal2
|
hyaluronidase 2
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of HYAL2 mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr 8:108,241,895...108,246,853
Ensembl chr 8:117,121,787...117,125,493
|
|
| G
|
Hyou1
|
hypoxia up-regulated 1
|
increases expression
|
ISO
|
Progesterone results in increased expression of HYOU1 mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr 8:53,602,882...53,614,998
Ensembl chr 8:53,602,604...53,614,997
|
|
| G
|
Icam1
|
intercellular adhesion molecule 1
|
multiple interactions decreases expression
|
ISO EXP
|
[Estradiol co-treated with Progesterone] results in decreased expression of ICAM1 protein; [Progesterone co-treated with Estradiol] results in increased expression of ICAM1 mRNA; Mifepristone inhibits the reaction [Progesterone inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 protein]]; MPO gene polymorphism affects the reaction [[Estradiol co-treated with Progesterone] results in decreased expression of ICAM1 protein]; Org 31710 inhibits the reaction [Progesterone inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 protein]]; Progesterone inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 protein] [Progesterone co-treated with Halothane] results in increased expression of ICAM1 mRNA; gadolinium chloride inhibits the reaction [[Progesterone co-treated with Halothane] results in increased expression of ICAM1 mRNA]; Mifepristone inhibits the reaction [Progesterone promotes the reaction [Halothane results in increased expression of ICAM1 mRNA]]; Progesterone promotes the reaction [Halothane results in increased expression of ICAM1 mRNA]; U 0126 inhibits the reaction [[Progesterone co-treated with Halothane] results in increased expression of ICAM1 mRNA] Progesterone results in decreased expression of ICAM1 mRNA; Progesterone results in decreased expression of ICAM1 protein
|
CTD |
PMID:15358673 PMID:17868700 PMID:20226447 PMID:21242819 PMID:21501669 PMID:22157104 PMID:22903158 More...
|
|
NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:27,829,161...27,841,617
|
|
| G
|
Icmt
|
isoprenylcysteine carboxyl methyltransferase
|
affects expression
|
ISO
|
Progesterone affects the expression of ICMT mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr 5:162,804,368...162,811,129
Ensembl chr 5:168,086,057...168,093,094
|
|
| G
|
Id1
|
inhibitor of DNA binding 1
|
increases expression decreases expression
|
ISO
|
Progesterone results in increased expression of ID1 mRNA Progesterone results in decreased expression of ID1 mRNA Progesterone results in decreased expression of ID1 protein
|
CTD |
PMID:18037150 PMID:18045962 PMID:22238285 |
|
NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:161,671,538...161,672,685
|
|
| G
|
Id2
|
inhibitor of DNA binding 2
|
increases expression multiple interactions
|
ISO
|
Progesterone results in increased expression of ID2 mRNA [Estradiol co-treated with Progesterone] results in decreased expression of ID2 mRNA
|
CTD |
PMID:18037150 PMID:20660070 |
|
NCBI chr 6:47,469,162...47,470,995
Ensembl chr 6:47,457,554...47,472,961
|
|
| G
|
Id3
|
inhibitor of DNA binding 3
|
increases expression
|
ISO
|
Progesterone results in increased expression of ID3 mRNA
|
CTD |
PMID:18037150 PMID:20864642 |
|
NCBI chr 5:153,656,253...153,657,860
Ensembl chr 5:153,630,498...153,657,856
|
|
| G
|
Id4
|
inhibitor of DNA binding 4
|
multiple interactions increases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of ID4 mRNA Progesterone results in increased expression of ID4 mRNA
|
CTD |
PMID:20660070 PMID:20864642 |
|
NCBI chr17:16,595,724...16,598,293
Ensembl chr17:16,595,724...16,598,492
|
|
| G
|
Idh1
|
isocitrate dehydrogenase (NADP(+)) 1
|
increases expression multiple interactions
|
ISO
|
Progesterone results in increased expression of IDH1 mRNA [Estradiol co-treated with Progesterone] results in increased expression of IDH1 mRNA
|
CTD |
PMID:18070364 PMID:20660070 |
|
NCBI chr 9:74,027,887...74,057,442
Ensembl chr 9:74,027,892...74,049,555
|
|
| G
|
Idi1
|
isopentenyl-diphosphate delta isomerase 1
|
increases expression
|
ISO
|
Progesterone results in increased expression of IDI1 mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr17:66,539,761...66,547,524
Ensembl chr17:66,539,763...66,547,524
|
|
| G
|
Ier3
|
immediate early response 3
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of IER3 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr20:2,933,173...2,934,377
Ensembl chr20:2,933,174...2,934,377
|
|
| G
|
Ier5l
|
immediate early response 5-like
|
increases expression
|
ISO
|
Progesterone results in increased expression of IER5L mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr 3:34,141,866...34,143,457
Ensembl chr 3:34,139,672...34,144,452
|
|
| G
|
Ifi44l
|
interferon-induced protein 44-like
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in increased expression of IFI44L mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr 2:240,668,742...240,706,425
Ensembl chr 2:243,328,723...243,366,404
|
|
| G
|
Ifit3
|
interferon-induced protein with tetratricopeptide repeats 3
|
multiple interactions increases expression
|
ISO
|
[Progesterone co-treated with TGFB1 protein] results in increased expression of IFIT3 mRNA Progesterone results in increased expression of IFIT3 mRNA
|
CTD |
PMID:21768398 |
|
NCBI chr 1:241,527,326...241,532,469
Ensembl chr 1:241,526,880...241,532,521
|
|
| G
|
Ifitm1
|
interferon induced transmembrane protein 1
|
increases expression
|
EXP
|
Progesterone results in increased expression of IFITM1 mRNA
|
CTD |
PMID:21770760 |
|
NCBI chr 1:196,067,163...196,069,169
Ensembl chr 1:205,496,807...205,498,776
|
|
| G
|
Ifitm2
|
interferon induced transmembrane protein 2
|
increases expression
|
EXP
|
Progesterone results in increased expression of IFITM2 mRNA
|
CTD |
PMID:21770760 |
|
NCBI chr 1:196,051,539...196,052,719
|
|
| G
|
Ifnar2
|
interferon alpha and beta receptor subunit 2
|
increases expression
|
ISO
|
Progesterone results in increased expression of IFNAR2 mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr11:44,099,574...44,131,941
Ensembl chr11:44,099,753...44,131,937
|
|
| G
|
Ifnb1
|
interferon beta 1
|
multiple interactions
|
ISO
|
Progesterone inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of IFNB1 mRNA]; Progesterone inhibits the reaction [Poly I-C results in increased expression of IFNB1 mRNA]
|
CTD |
PMID:22546503 |
|
NCBI chr 5:108,066,650...108,067,487
Ensembl chr 5:108,066,650...108,067,487
|
|
| G
|
Ifng
|
interferon gamma
|
increases expression multiple interactions
|
ISO
|
Progesterone results in increased expression of IFNG protein [Progesterone co-treated with Estradiol] inhibits the reaction [Vaccines, Virus-Like Particle results in increased expression of IFNG protein]; Progesterone inhibits the reaction [Vaccines, Virus-Like Particle results in increased expression of IFNG protein] Progesterone inhibits the reaction [[IFNG protein co-treated with TNF protein] results in increased abundance of Nitric Oxide]
|
CTD |
PMID:11063824 PMID:15804489 PMID:20130130 |
|
NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216
|
|
| G
|
Ifngr1
|
interferon gamma receptor 1
|
decreases expression increases expression
|
ISO
|
Progesterone results in decreased expression of IFNGR1 mRNA Progesterone results in increased expression of IFNGR1 mRNA
|
CTD |
PMID:18692832 PMID:21540246 |
|
NCBI chr 1:16,152,811...16,171,439
Ensembl chr 1:16,152,879...16,171,437
|
|
| G
|
Ifrd1
|
interferon-related developmental regulator 1
|
increases expression
|
ISO
|
Progesterone results in increased expression of IFRD1 mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr 6:62,996,560...63,044,996
Ensembl chr 6:62,996,562...63,016,131
|
|
| G
|
Ift70a2
|
intraflagellar transport 70A2
|
increases expression
|
ISO
|
Progesterone results in increased expression of IFT70A mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr 3:60,899,193...60,901,634
Ensembl chr 3:81,307,245...81,320,093
|
|
| G
|
Ift74
|
intraflagellar transport 74
|
increases expression
|
ISO
|
Progesterone results in increased expression of IFT74 mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr 5:109,460,372...109,563,839
Ensembl chr 5:114,593,397...114,679,581
|
|
| G
|
Igf1
|
insulin-like growth factor 1
|
multiple interactions increases abundance increases expression affects expression increases secretion
|
ISO EXP
|
[Estradiol co-treated with Progesterone] results in increased secretion of IGF1 protein; [IGF1 protein co-treated with FSHB protein] results in increased abundance of Progesterone; ADIPOQ protein promotes the reaction [IGF1 protein results in increased abundance of Progesterone]; FGF9 protein inhibits the reaction [[IGF1 protein co-treated with FSHB protein] results in increased abundance of Progesterone]; FGF9 protein inhibits the reaction [IGF1 protein promotes the reaction [Bucladesine results in increased abundance of Progesterone]]; FGF9 protein inhibits the reaction [IGF1 protein promotes the reaction [Colforsin results in increased abundance of Progesterone]]; FGF9 protein inhibits the reaction [IGF1 protein results in increased abundance of Progesterone]; IGF1 protein promotes the reaction [Bucladesine results in increased abundance of Progesterone]; IGF1 protein promotes the reaction [Colforsin results in increased abundance of Progesterone]; Mifepristone inhibits the reaction [[Estradiol co-treated with Progesterone] results in increased secretion of IGF1 protein]; Mifepristone inhibits the reaction [Progesterone results in increased secretion of IGF1 protein]; NAMPT protein promotes the reaction [IGF1 protein results in increased abundance of Progesterone]; Tamoxifen inhibits the reaction [[Estradiol co-treated with Progesterone] results in increased secretion of IGF1 protein] IGF1 protein inhibits the reaction [BMP15 protein inhibits the reaction [FSHB protein results in increased abundance of Progesterone]]; IGF1 protein inhibits the reaction [BMP2 protein inhibits the reaction [FSHB protein results in increased abundance of Progesterone]]; IGF1 protein inhibits the reaction [BMP4 protein inhibits the reaction [FSHB protein results in increased abundance of Progesterone]]; IGF1 protein inhibits the reaction [BMP6 protein inhibits the reaction [FSHB protein results in increased abundance of Progesterone]]; IGF1 protein inhibits the reaction [BMP7 protein inhibits the reaction [FSHB protein results in increased abundance of Progesterone]]; IGF1 protein promotes the reaction [[FSHB protein results in increased expression of CYP11A1 mRNA] which results in increased abundance of Progesterone]; IGF1 protein promotes the reaction [[FSHB protein results in increased expression of CYP19A1 mRNA] which results in increased abundance of Progesterone]; IGF1 protein promotes the reaction [[FSHB protein results in increased expression of HSD3B2 mRNA] which results in increased abundance of Progesterone]; IGF1 protein promotes the reaction [[FSHB protein results in increased expression of STAR mRNA] which results in increased abundance of Progesterone]; IGF1 protein promotes the reaction [FSHB protein results in increased abundance of Progesterone]; RETN protein promotes the reaction [IGF1 protein results in increased abundance of Progesterone] Progesterone results in increased expression of IGF1 mRNA [Estradiol co-treated with Progesterone] promotes the reaction [Cuprizone results in increased expression of IGF1 mRNA]; Estradiol promotes the reaction [Progesterone results in increased expression of IGF1 mRNA]; IGF1 protein affects the susceptibility to [Progesterone co-treated with Estrogens]; IGF1 protein inhibits the reaction [[Progesterone co-treated with Estrogens] results in increased expression of IGFBP3 mRNA]; IGF1 protein inhibits the reaction [[Progesterone co-treated with Estrogens] results in increased expression of RBP1 mRNA]; IGF1 protein inhibits the reaction [[Progesterone co-treated with Estrogens] results in increased expression of TGFB1 mRNA]; IGF1 protein inhibits the reaction [[Progesterone co-treated with Estrogens] results in increased expression of TRP53 mRNA]; Progesterone promotes the reaction [Estradiol results in increased expression of IGF1 mRNA] Progesterone affects the expression of IGF1 mRNA
|
CTD |
PMID:8390853 PMID:15809018 PMID:17251523 PMID:18562952 PMID:19031445 PMID:19081562 PMID:19853640 PMID:20726854 PMID:20864642 PMID:21239528 PMID:21770760 PMID:22067323 PMID:22798350 PMID:23315983 More...
|
|
NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:24,130,137...24,246,764
|
|
| G
|
Igf1r
|
insulin-like growth factor 1 receptor
|
decreases expression increases expression multiple interactions
|
ISO EXP
|
Progesterone results in decreased expression of IGF1R mRNA Progesterone results in increased expression of IGF1R mRNA [Estradiol co-treated with Progesterone co-treated with Methylnitrosourea] results in increased expression of IGF1R mRNA; [Estradiol co-treated with Progesterone co-treated with Methylnitrosourea] results in increased expression of IGF1R protein
|
CTD |
PMID:18070364 PMID:19853640 PMID:22465879 |
|
NCBI chr 1:121,549,831...121,838,548
Ensembl chr 1:130,959,997...131,248,664
|
|
| G
|
Igf2
|
insulin-like growth factor 2
|
increases expression
|
ISO
|
Progesterone results in increased expression of IGF2 mRNA
|
CTD |
PMID:18497975 |
|
NCBI chr 1:207,243,873...207,261,263
Ensembl chr 1:207,243,873...207,260,667
|
|
| G
|
Igfbp1
|
insulin-like growth factor binding protein 1
|
affects expression increases secretion increases expression multiple interactions
|
ISO
|
Progesterone affects the expression of IGFBP1 mRNA; Progesterone affects the expression of IGFBP1 protein Progesterone results in increased secretion of IGFBP1 protein Progesterone results in increased expression of IGFBP1 mRNA 4'-cyanobiphenyl-4-sulfonic acid (6-aminopyridin-2-yl)amide inhibits the reaction [Progesterone promotes the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of IGFBP1 mRNA]]; [Cyclic AMP co-treated with Estradiol co-treated with Progesterone] results in increased expression of IGFBP1 mRNA; [Estradiol co-treated with Progesterone] results in increased expression of IGFBP1 mRNA; [Estradiol co-treated with Progesterone] results in increased secretion of IGFBP1 protein; [Progesterone co-treated with bisphenol A] results in increased expression of IGFBP1 mRNA; [Progesterone co-treated with Estradiol] results in increased expression of IGFBP1 mRNA; [Progesterone co-treated with Triclosan] results in increased expression of IGFBP1 mRNA; BMP7 protein inhibits the reaction [[Estradiol co-treated with Progesterone] results in increased expression of IGFBP1 mRNA]; BMP7 protein inhibits the reaction [[Estradiol co-treated with Progesterone] results in increased secretion of IGFBP1 protein]; Hydrocortisone promotes the reaction [Progesterone promotes the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of IGFBP1 mRNA]]; Mifepristone inhibits the reaction [Progesterone results in increased secretion of IGFBP1 protein]; Progesterone inhibits the reaction [Estradiol results in increased expression of IGFBP1 protein]; Progesterone promotes the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of IGFBP1 mRNA]; Progesterone promotes the reaction [Triclosan results in increased secretion of IGFBP1 protein]
|
CTD |
PMID:15501902 PMID:17404688 PMID:17484513 PMID:18815356 PMID:20085912 PMID:20864642 PMID:23275455 PMID:26604029 PMID:32446389 More...
|
|
NCBI chr14:86,261,277...86,266,344
Ensembl chr14:86,261,277...86,266,344
|
|
| G
|
Igfbp2
|
insulin-like growth factor binding protein 2
|
multiple interactions increases expression increases secretion decreases expression
|
ISO EXP
|
[Estradiol co-treated with Progesterone] results in increased secretion of IGFBP2 protein Progesterone results in increased expression of IGFBP2 mRNA Progesterone results in increased secretion of IGFBP2 protein Progesterone results in decreased expression of IGFBP2 mRNA
|
CTD |
PMID:15809018 PMID:18070364 PMID:19853640 |
|
NCBI chr 9:74,415,574...74,442,945
Ensembl chr 9:81,864,783...81,892,171
|
|
| G
|
Igfbp3
|
insulin-like growth factor binding protein 3
|
multiple interactions increases expression affects expression decreases secretion decreases expression
|
ISO EXP
|
[Estradiol co-treated with Progesterone] results in decreased expression of IGFBP3 mRNA; [Estradiol co-treated with Progesterone] results in decreased secretion of IGFBP3 protein; [Progesterone affects the activity of PGR protein alternative form] which affects the expression of IGFBP3 mRNA; [Progesterone co-treated with Estradiol] results in decreased expression of IGFBP3 mRNA Progesterone results in increased expression of IGFBP3 mRNA [Progesterone co-treated with Estrogens] results in increased expression of IGFBP3 mRNA; IGF1 protein inhibits the reaction [[Progesterone co-treated with Estrogens] results in increased expression of IGFBP3 mRNA] Progesterone affects the expression of IGFBP3; Progesterone affects the expression of IGFBP3 mRNA Progesterone results in decreased secretion of IGFBP3 protein Progesterone results in decreased expression of IGFBP3 mRNA
|
CTD |
PMID:15178747 PMID:15809018 PMID:15866122 PMID:17251523 PMID:17404688 PMID:18070364 PMID:18562952 PMID:19341330 PMID:20660070 PMID:20726854 PMID:22238285 More...
|
|
NCBI chr14:86,270,208...86,277,944
Ensembl chr14:86,270,208...86,277,944
|
|
| G
|
Igfbp4
|
insulin-like growth factor binding protein 4
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of IGFBP4 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr10:84,491,471...84,503,487
Ensembl chr10:84,485,775...84,503,473
|
|
| G
|
Igfbp5
|
insulin-like growth factor binding protein 5
|
multiple interactions decreases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of IGFBP5 mRNA Progesterone results in decreased expression of IGFBP5 mRNA
|
CTD |
PMID:18070364 PMID:20660070 PMID:20864642 |
|
NCBI chr 9:81,901,605...81,914,187
Ensembl chr 9:81,897,616...81,914,390
|
|
| G
|
Igfbp6
|
insulin-like growth factor binding protein 6
|
decreases expression increases expression
|
ISO EXP
|
Progesterone results in decreased expression of IGFBP6 mRNA Progesterone results in increased expression of IGFBP6 mRNA
|
CTD |
PMID:19853640 PMID:20864642 PMID:22238285 |
|
NCBI chr 7:135,154,919...135,159,550
Ensembl chr 7:135,154,685...135,159,795
|
|
| G
|
Igkc
|
immunoglobulin kappa constant
|
increases expression multiple interactions
|
ISO
|
Progesterone results in increased expression of IGKC mRNA [Estradiol co-treated with Progesterone] results in decreased expression of IGKC mRNA
|
CTD |
PMID:17404688 PMID:20660070 |
|
|
|
| G
|
Ihh
|
Indian hedgehog signaling molecule
|
affects expression multiple interactions increases expression
|
ISO
|
Progesterone affects the expression of IHH [Estradiol co-treated with Progesterone co-treated with Corn Oil] results in increased expression of IHH mRNA; [Estradiol co-treated with Progesterone] results in increased expression of IHH mRNA; ESR1 protein promotes the reaction [[Estradiol co-treated with Progesterone] results in increased expression of IHH mRNA] [Estradiol co-treated with Progesterone] results in decreased expression of IHH mRNA Progesterone results in increased expression of IHH; Progesterone results in increased expression of IHH mRNA
|
CTD |
PMID:16794005 PMID:20232216 PMID:20660070 PMID:22238285 PMID:22958837 PMID:25210133 PMID:32186404 More...
|
|
NCBI chr 9:83,952,986...83,959,203
Ensembl chr 9:83,952,986...83,959,203
|
|
| G
|
Ikbkb
|
inhibitor of nuclear factor kappa B kinase subunit beta
|
increases expression
|
ISO
|
Progesterone results in increased expression of IKBKB mRNA
|
CTD |
PMID:21549006 |
|
NCBI chr16:69,319,487...69,373,251
Ensembl chr16:76,022,008...76,081,911
|
|
| G
|
Ikbkg
|
inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of IKBKG mRNA
|
CTD |
PMID:18556351 |
|
NCBI chr X:157,358,279...157,397,563
Ensembl chr X:157,367,639...157,392,757
|
|
| G
|
Il10
|
interleukin 10
|
decreases expression increases expression multiple interactions
|
ISO
|
Progesterone results in decreased expression of IL10 protein Progesterone results in increased expression of IL10 mRNA [Progesterone co-treated with Estradiol] promotes the reaction [Vaccines, Virus-Like Particle results in increased expression of IL10 protein]; Progesterone promotes the reaction [Vaccines, Virus-Like Particle results in increased expression of IL10 protein] Progesterone results in increased expression of IL10 protein
|
CTD |
PMID:15804489 PMID:20130130 PMID:21856019 PMID:22615136 |
|
NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580
|
|
| G
|
Il11
|
interleukin 11
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased secretion of IL11 protein; IL11 protein promotes the reaction [[Estradiol co-treated with Progesterone] results in increased secretion of PRL protein]; IL11 protein promotes the reaction [INHBA protein promotes the reaction [[Estradiol co-treated with Progesterone] results in increased secretion of PRL protein]]; INHBA protein promotes the reaction [IL11 protein promotes the reaction [[Estradiol co-treated with Progesterone] results in increased secretion of PRL protein]]
|
CTD |
PMID:20074812 |
|
NCBI chr 1:78,098,622...78,104,915
Ensembl chr 1:78,096,930...78,104,915
|
|
| G
|
Il12a
|
interleukin 12A
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of IL12A mRNA [Progesterone co-treated with Estradiol] inhibits the reaction [Vaccines, Virus-Like Particle results in increased expression of [IL12A protein binds to IL12B protein]]; Progesterone inhibits the reaction [Vaccines, Virus-Like Particle results in increased expression of [IL12A protein binds to IL12B protein]]; Progesterone results in increased expression of [IL12A protein binds to IL12B protein]
|
CTD |
PMID:19693291 PMID:20130130 |
|
NCBI chr 2:155,275,734...155,282,997
Ensembl chr 2:155,275,625...155,282,997
|
|
| G
|
Il12b
|
interleukin 12B
|
multiple interactions
|
ISO
|
Progesterone inhibits the reaction [[Lipopolysaccharides co-treated with IL4 protein] results in increased expression of IL12B mRNA]; Progesterone inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA] [Progesterone co-treated with Estradiol] inhibits the reaction [Vaccines, Virus-Like Particle results in increased expression of [IL12A protein binds to IL12B protein]]; Progesterone inhibits the reaction [Vaccines, Virus-Like Particle results in increased expression of [IL12A protein binds to IL12B protein]]; Progesterone results in increased expression of [IL12A protein binds to IL12B protein]
|
CTD |
PMID:20130130 PMID:21977998 |
|
NCBI chr10:29,390,300...29,405,194
Ensembl chr10:29,389,905...29,405,194
|
|
| G
|
Il13ra1
|
interleukin 13 receptor subunit alpha 1
|
decreases expression increases expression
|
ISO EXP
|
Progesterone results in decreased expression of IL13RA1 mRNA Progesterone results in increased expression of IL13RA1 mRNA
|
CTD |
PMID:21770760 PMID:21795739 |
|
NCBI chr X:120,213,670...120,294,777
Ensembl chr X:120,214,075...120,274,461
|
|
| G
|
Il13ra2
|
interleukin 13 receptor subunit alpha 2
|
multiple interactions decreases expression
|
ISO
|
4-(2-aminoethyl)benzenesulfonylfluoride inhibits the reaction [[Estradiol co-treated with Progesterone] results in decreased expression of IL13RA2 mRNA]; [Estradiol co-treated with Progesterone] results in decreased expression of IL13RA2 mRNA; N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide inhibits the reaction [[Estradiol co-treated with Progesterone] results in decreased expression of IL13RA2 mRNA]; U 0126 promotes the reaction [[Estradiol co-treated with Progesterone] results in decreased expression of IL13RA2 mRNA] Progesterone results in decreased expression of IL13RA2 mRNA
|
CTD |
PMID:20660070 PMID:20864642 |
|
NCBI chr X:115,814,620...115,886,080
Ensembl chr X:115,814,622...115,841,455
|
|
| G
|
Il15
|
interleukin 15
|
multiple interactions increases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of IL15 mRNA; [Progesterone co-treated with Estradiol] results in increased expression of IL15 mRNA Progesterone results in increased expression of IL15 mRNA
|
CTD |
PMID:17404688 PMID:18692832 PMID:20660070 |
|
NCBI chr19:25,640,025...25,706,818
Ensembl chr19:42,545,346...42,611,348
|
|
| G
|
Il15ra
|
interleukin 15 receptor subunit alpha
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in increased expression of IL15RA mRNA
|
CTD |
PMID:18692832 |
|
NCBI chr17:71,712,141...71,742,072
Ensembl chr17:71,712,141...71,742,149
|
|
| G
|
Il17a
|
interleukin 17A
|
multiple interactions
|
ISO
|
Mifepristone inhibits the reaction [Progesterone promotes the reaction [Halothane results in increased expression of IL17A protein]]; Progesterone promotes the reaction [Budesonide inhibits the reaction [Ozone results in increased expression of IL17A protein]]; Progesterone promotes the reaction [Halothane results in increased expression of IL17A protein]
|
CTD |
PMID:21501669 PMID:28279894 |
|
NCBI chr 9:30,640,844...30,644,331
Ensembl chr 9:30,640,844...30,644,331
|
|
| G
|
Il17rb
|
interleukin 17 receptor B
|
multiple interactions decreases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of IL17RB mRNA Progesterone results in decreased expression of IL17RB mRNA
|
CTD |
PMID:20660070 PMID:21273126 |
|
NCBI chr16:5,186,961...5,200,657
Ensembl chr16:5,186,961...5,200,694
|
|
| G
|
Il17rd
|
interleukin 17 receptor D
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of IL17RD mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr16:2,235,172...2,489,827
Ensembl chr16:2,235,169...2,301,850
|
|
| G
|
Il17re
|
interleukin 17 receptor E
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of IL17RE mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 4:148,160,384...148,173,830
Ensembl chr 4:148,159,475...148,173,827
|
|
| G
|
Il18
|
interleukin 18
|
multiple interactions
|
ISO
|
[fulvestrant co-treated with Mifepristone] inhibits the reaction [[Progesterone co-treated with Estrogens] inhibits the reaction [Lipopolysaccharides results in increased expression of IL18 mRNA]]; [Progesterone co-treated with Estrogens] inhibits the reaction [Lipopolysaccharides results in increased expression of IL18 mRNA]; Progesterone inhibits the reaction [Lipopolysaccharides results in increased expression of IL18 mRNA]
|
CTD |
PMID:17850464 |
|
NCBI chr 8:59,802,072...59,829,275
Ensembl chr 8:59,809,592...59,831,286
|
|
| G
|
Il18r1
|
interleukin 18 receptor 1
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of IL18R1 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 9:50,223,274...50,257,370
Ensembl chr 9:50,223,200...50,257,367
|
|
| G
|
Il1b
|
interleukin 1 beta
|
multiple interactions decreases expression increases expression decreases activity affects expression
|
ISO EXP
|
[[IL6 protein co-treated with IL1B protein co-treated with TNF protein] affects the susceptibility to [Testosterone co-treated with Estradiol co-treated with Progesterone]] which affects the abundance of Lipids; [[IL6 protein co-treated with IL1B protein co-treated with TNF protein] affects the susceptibility to [Testosterone co-treated with Estradiol co-treated with Progesterone]] which affects the abundance of Reactive Oxygen Species; [[IL6 protein co-treated with IL1B protein co-treated with TNF protein] affects the susceptibility to [Testosterone co-treated with Estradiol co-treated with Progesterone]] which affects the expression of ALB protein; [[Testosterone co-treated with Estradiol co-treated with Progesterone] affects the susceptibility to [IL6 protein co-treated with IL1B protein co-treated with TNF protein]] which affects the abundance of Lipids; [[Testosterone co-treated with Estradiol co-treated with Progesterone] affects the susceptibility to [IL6 protein co-treated with IL1B protein co-treated with TNF protein]] which affects the abundance of Reactive Oxygen Species; [[Testosterone co-treated with Estradiol co-treated with Progesterone] affects the susceptibility to [IL6 protein co-treated with IL1B protein co-treated with TNF protein]] which affects the expression of ALB protein; [Estrogens co-treated with Progesterone co-treated with IL1B protein] results in increased expression of MMP14 mRNA; [Estrogens co-treated with Progesterone co-treated with IL1B protein] results in increased expression of MMP3 mRNA; [IL6 protein co-treated with IL1B protein co-treated with TNF protein] affects the susceptibility to [Testosterone co-treated with Estradiol co-treated with Progesterone]; [Progesterone co-treated with IL1B protein] results in increased expression of INHBA mRNA; [Progesterone co-treated with IL1B protein] results in increased secretion of [INHBA protein binds to INHBA protein]; [Testosterone co-treated with Estradiol co-treated with Progesterone] affects the susceptibility to [IL6 protein co-treated with IL1B protein co-treated with TNF protein]; Progesterone inhibits the reaction [IL1B protein results in increased degradation of NFKBIA protein]; Progesterone inhibits the reaction [IL1B protein results in increased expression of MMP1 protein modified form]; Progesterone inhibits the reaction [IL1B protein results in increased expression of MMP2 protein modified form]; Progesterone inhibits the reaction [IL1B protein results in increased expression of MMP3 protein modified form]; Progesterone inhibits the reaction [IL1B protein results in increased expression of MMP9 protein modified form]; Progesterone inhibits the reaction [Vaccines, Virus-Like Particle results in increased expression of IL1B protein] Progesterone results in decreased expression of IL1B mRNA Progesterone results in increased expression of IL1B mRNA; Progesterone results in increased expression of IL1B protein Progesterone results in decreased activity of IL1B protein Mifepristone inhibits the reaction [Progesterone promotes the reaction [Halothane results in increased expression of IL1B mRNA]]; Progesterone promotes the reaction [Halothane results in increased expression of IL1B mRNA] Progesterone results in decreased expression of IL1B protein Progesterone affects the expression of IL1B mRNA
|
CTD |
PMID:17251523 PMID:17437195 PMID:17636213 PMID:17868700 PMID:18570937 PMID:20130130 PMID:20621171 PMID:21501669 PMID:21540246 PMID:21549006 PMID:22219637 PMID:22615136 More...
|
|
NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
|
|
| G
|
Il1r1
|
interleukin 1 receptor type 1
|
increases expression
|
ISO EXP
|
Progesterone results in increased expression of IL1R1 mRNA
|
CTD |
PMID:20726854 PMID:20864642 PMID:21795739 |
|
NCBI chr 9:50,000,558...50,076,579
Ensembl chr 9:50,000,566...50,076,579
|
|
| G
|
Il1r2
|
interleukin 1 receptor type 2
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of IL1R2 mRNA
|
CTD |
PMID:19693291 |
|
NCBI chr 9:42,384,280...42,424,726
Ensembl chr 9:49,877,266...49,920,374
|
|
| G
|
Il1rl1
|
interleukin 1 receptor-like 1
|
increases expression multiple interactions decreases expression
|
ISO EXP
|
Progesterone results in increased expression of IL1RL1 mRNA [Progesterone co-treated with Estradiol] results in increased expression of IL1RL1 mRNA Progesterone results in decreased expression of IL1RL1 mRNA
|
CTD |
PMID:17404688 PMID:18692832 PMID:19000923 PMID:20726854 |
|
NCBI chr 9:50,157,326...50,222,888
Ensembl chr 9:50,204,551...50,222,891
|
|
| G
|
Il1rn
|
interleukin 1 receptor antagonist
|
increases expression
|
EXP
|
Progesterone results in increased expression of IL1RN mRNA
|
CTD |
PMID:21770760 |
|
NCBI chr 3:27,509,836...27,525,738
Ensembl chr 3:27,509,798...27,525,732
|
|
| G
|
Il2
|
interleukin 2
|
multiple interactions
|
ISO
|
Progesterone promotes the reaction [IL2 protein results in increased phosphorylation of STAT5A protein]; Progesterone promotes the reaction [IL2 protein results in increased phosphorylation of STAT5B protein]
|
CTD |
PMID:21768398 |
|
NCBI chr 2:121,932,968...121,937,672
Ensembl chr 2:121,932,968...121,937,672
|
|
| G
|
Il20ra
|
interleukin 20 receptor subunit alpha
|
multiple interactions increases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of IL20RA mRNA; [Progesterone co-treated with Estradiol] results in increased expression of IL20RA mRNA Progesterone results in increased expression of IL20RA mRNA
|
CTD |
PMID:17404688 PMID:20660070 |
|
NCBI chr 1:16,243,683...16,313,229
Ensembl chr 1:16,243,801...16,313,221
|
|
| G
|
Il24
|
interleukin 24
|
multiple interactions decreases expression
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of IL24 mRNA Progesterone results in decreased expression of IL24 mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr13:44,905,362...44,910,760
Ensembl chr13:44,905,363...44,910,760
|
|
| G
|
Il2rb
|
interleukin 2 receptor subunit beta
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of IL2RB mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr 7:110,033,341...110,048,054
Ensembl chr 7:111,913,828...111,928,537
|
|
| G
|
Il33
|
interleukin 33
|
multiple interactions increases expression decreases expression
|
ISO EXP
|
[Estradiol co-treated with Progesterone] results in decreased expression of IL33 mRNA; [Progesterone co-treated with Estradiol] results in decreased expression of IL33 mRNA Progesterone results in increased expression of IL33 mRNA Progesterone results in decreased expression of IL33 mRNA
|
CTD |
PMID:17404688 PMID:20660070 PMID:21770760 |
|
NCBI chr 1:237,115,478...237,149,897
Ensembl chr 1:237,115,572...237,150,901
|
|
| G
|
Il36a
|
interleukin 36, alpha
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of IL36A mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 3:27,395,146...27,399,695
Ensembl chr 3:27,395,146...27,399,695
|
|
| G
|
Il4
|
interleukin 4
|
decreases expression increases expression multiple interactions
|
ISO
|
Progesterone results in decreased expression of IL4 protein Progesterone results in increased expression of IL4 mRNA Progesterone inhibits the reaction [[Lipopolysaccharides co-treated with IL4 protein] results in increased expression of ARG1 mRNA]; Progesterone inhibits the reaction [[Lipopolysaccharides co-treated with IL4 protein] results in increased expression of IL12B mRNA]; Progesterone inhibits the reaction [[Lipopolysaccharides co-treated with IL4 protein] results in increased expression of NOS2 mRNA]; Progesterone inhibits the reaction [IL4 protein results in increased expression of ARG1 mRNA]; Progesterone inhibits the reaction [IL4 protein results in increased expression of MRC1 mRNA]; Progesterone inhibits the reaction [IL4 protein results in increased expression of RETNLA mRNA]; Progesterone promotes the reaction [[IL4 protein co-treated with Lipopolysaccharides] results in increased expression of CHIL3 mRNA]; Progesterone promotes the reaction [[IL4 protein co-treated with Lipopolysaccharides] results in increased expression of RETNLA mRNA]; Progesterone promotes the reaction [IL4 protein results in increased expression of CHIL3 mRNA]
|
CTD |
PMID:15804489 PMID:21977998 PMID:22615136 |
|
NCBI chr10:38,272,003...38,277,549
Ensembl chr10:38,272,003...38,277,549
|
|
| G
|
Il4r
|
interleukin 4 receptor
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of IL4R mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 1:189,545,739...189,570,639
Ensembl chr 1:189,544,988...189,570,636
|
|
| G
|
Il6
|
interleukin 6
|
decreases secretion multiple interactions increases expression decreases expression affects expression
|
ISO EXP
|
Progesterone results in decreased secretion of IL6 protein [Estradiol co-treated with Progesterone] results in decreased expression of IL6 mRNA; [Estradiol co-treated with Progesterone] results in decreased expression of IL6 protein Progesterone results in increased expression of IL6 mRNA Mifepristone inhibits the reaction [Progesterone promotes the reaction [Halothane results in increased expression of IL6 mRNA]]; MIR155 mRNA inhibits the reaction [Progesterone inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of IL6 protein]]; Progesterone inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of IL6 protein]; Progesterone promotes the reaction [Budesonide inhibits the reaction [Ozone results in increased expression of IL6 protein]]; Progesterone promotes the reaction [Halothane results in increased expression of IL6 mRNA] Progesterone results in decreased expression of IL6 protein Progesterone affects the expression of IL6 mRNA [[IL6 protein co-treated with IL1B protein co-treated with TNF protein] affects the susceptibility to [Testosterone co-treated with Estradiol co-treated with Progesterone]] which affects the abundance of Lipids; [[IL6 protein co-treated with IL1B protein co-treated with TNF protein] affects the susceptibility to [Testosterone co-treated with Estradiol co-treated with Progesterone]] which affects the abundance of Reactive Oxygen Species; [[IL6 protein co-treated with IL1B protein co-treated with TNF protein] affects the susceptibility to [Testosterone co-treated with Estradiol co-treated with Progesterone]] which affects the expression of ALB protein; [[Testosterone co-treated with Estradiol co-treated with Progesterone] affects the susceptibility to [IL6 protein co-treated with IL1B protein co-treated with TNF protein]] which affects the abundance of Lipids; [[Testosterone co-treated with Estradiol co-treated with Progesterone] affects the susceptibility to [IL6 protein co-treated with IL1B protein co-treated with TNF protein]] which affects the abundance of Reactive Oxygen Species; [[Testosterone co-treated with Estradiol co-treated with Progesterone] affects the susceptibility to [IL6 protein co-treated with IL1B protein co-treated with TNF protein]] which affects the expression of ALB protein; [IL6 protein co-treated with IL1B protein co-treated with TNF protein] affects the susceptibility to [Testosterone co-treated with Estradiol co-treated with Progesterone]; [Proteoglycans co-treated with Progesterone] inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; [Proteoglycans co-treated with Progesterone] inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]; [Testosterone co-treated with Estradiol co-treated with Progesterone] affects the susceptibility to [IL6 protein co-treated with IL1B protein co-treated with TNF protein]; Progesterone inhibits the reaction [[Lipopolysaccharides co-treated with HMGB1 protein] results in increased expression of IL6 protein]; Progesterone inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein]; Progesterone inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL6 mRNA]; Progesterone inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL6 protein]; Progesterone inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; Progesterone inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]; Progesterone inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]
|
CTD |
PMID:15804489 PMID:16134523 PMID:17000234 PMID:17251523 PMID:20621171 PMID:21277368 PMID:21501669 PMID:21768398 PMID:21795739 PMID:22014880 PMID:22122352 PMID:22314502 PMID:22546503 PMID:28279894 More...
|
|
NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
|
|
| G
|
Il6r
|
interleukin 6 receptor
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of IL6R mRNA; Progesterone results in decreased expression of IL6R protein
|
CTD |
PMID:21768398 |
|
NCBI chr 2:177,582,020...177,646,705
Ensembl chr 2:177,582,164...177,645,221
|
|
| G
|
Il6st
|
interleukin 6 cytokine family signal transducer
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in increased expression of IL6ST mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr 2:45,798,872...45,839,501
Ensembl chr 2:45,799,380...45,843,182
|
|
| G
|
Il7r
|
interleukin 7 receptor
|
decreases expression increases expression
|
ISO EXP
|
Progesterone results in decreased expression of IL7R mRNA Progesterone results in increased expression of IL7R mRNA
|
CTD |
PMID:21770760 PMID:21795739 |
|
NCBI chr 2:60,179,561...60,204,937
Ensembl chr 2:60,181,382...60,211,027
|
|
| G
|
Impa2
|
inositol monophosphatase 2
|
increases expression
|
ISO
|
Progesterone results in increased expression of IMPA2 mRNA
|
CTD |
PMID:20864642 PMID:21540246 PMID:21795739 |
|
NCBI chr18:60,834,206...60,867,575
Ensembl chr18:63,104,083...63,137,543
|
|
| G
|
Inha
|
inhibin subunit alpha
|
multiple interactions increases expression decreases abundance
|
ISO EXP
|
INHA mutant form inhibits the reaction [FSHB protein results in increased secretion of Progesterone]; INHA mutant form inhibits the reaction [GDF9 protein inhibits the reaction [INHBA protein inhibits the reaction [FSHB protein results in increased secretion of Progesterone]]] Progesterone results in increased expression of INHA mRNA INHA protein results in decreased abundance of Progesterone
|
CTD |
PMID:18992787 PMID:20660033 PMID:22285243 |
|
NCBI chr 9:76,994,465...76,997,366
Ensembl chr 9:84,443,109...84,446,009
|
|
| G
|
Inhba
|
inhibin subunit beta A
|
multiple interactions increases expression decreases expression decreases secretion
|
ISO EXP
|
4-(2-aminoethyl)benzenesulfonylfluoride inhibits the reaction [[Estradiol co-treated with Progesterone] results in decreased expression of INHBA mRNA]; [Estradiol co-treated with Progesterone] results in decreased expression of INHBA mRNA; [Progesterone co-treated with IL1B protein] results in increased expression of INHBA mRNA; [Progesterone co-treated with IL1B protein] results in increased secretion of [INHBA protein binds to INHBA protein]; FST protein inhibits the reaction [INHBA protein inhibits the reaction [Colforsin results in increased secretion of Progesterone]]; GDF9 protein inhibits the reaction [INHBA protein inhibits the reaction [FSHB protein results in increased secretion of Progesterone]]; GDF9 protein inhibits the reaction [INHBA protein results in decreased secretion of Progesterone]; IL11 protein promotes the reaction [INHBA protein promotes the reaction [[Estradiol co-treated with Progesterone] results in increased secretion of PRL protein]]; INHA mutant form inhibits the reaction [GDF9 protein inhibits the reaction [INHBA protein inhibits the reaction [FSHB protein results in increased secretion of Progesterone]]]; INHBA protein inhibits the reaction [Colforsin results in increased secretion of Progesterone]; INHBA protein inhibits the reaction [FSHB protein results in increased secretion of Progesterone]; INHBA protein promotes the reaction [[Estradiol co-treated with Progesterone] results in increased secretion of PRL protein]; INHBA protein promotes the reaction [IL11 protein promotes the reaction [[Estradiol co-treated with Progesterone] results in increased secretion of PRL protein]]; N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide inhibits the reaction [[Estradiol co-treated with Progesterone] results in decreased expression of INHBA mRNA]; pepstatin inhibits the reaction [[Estradiol co-treated with Progesterone] results in decreased expression of INHBA mRNA]; Progesterone results in increased secretion of [INHBA protein binds to INHBA protein] Progesterone results in increased expression of INHBA mRNA Progesterone results in decreased expression of INHBA mRNA
|
CTD |
PMID:17636213 PMID:17954979 PMID:18070364 PMID:18936084 PMID:20074812 PMID:20660033 PMID:20660070 PMID:22285243 More...
|
|
NCBI chr17:49,091,635...49,111,573
Ensembl chr17:53,791,444...53,804,508
|
|
| G
|
Inhbb
|
inhibin subunit beta B
|
increases expression
|
ISO
|
Progesterone results in increased expression of INHBB mRNA
|
CTD |
PMID:21795739 |
|
NCBI chr13:33,083,671...33,089,373
Ensembl chr13:33,083,671...33,089,609
|
|
| G
|
Inmt
|
indolethylamine N-methyltransferase
|
affects expression increases expression
|
ISO
|
Progesterone affects the expression of INMT mRNA Progesterone results in increased expression of INMT mRNA
|
CTD |
PMID:17251523 PMID:22238285 |
|
NCBI chr 4:85,648,459...85,652,755
Ensembl chr 4:85,648,459...85,652,755
|
|
| G
|
Inpp4b
|
inositol polyphosphate-4-phosphatase type II B
|
multiple interactions decreases expression
|
ISO
|
Progesterone inhibits the reaction [Estradiol results in increased expression of INPP4B mRNA] Progesterone results in decreased expression of INPP4B mRNA
|
CTD |
PMID:20864642 PMID:21795739 |
|
NCBI chr19:42,824,710...43,575,039
Ensembl chr19:42,829,871...43,185,091
|
|
| G
|
Ins1
|
insulin 1
|
multiple interactions
|
ISO
|
1,4-bis(2-(3,5-dichloropyridyloxy))benzene inhibits the reaction [[Progesterone co-treated with Estradiol] results in increased expression of INS1 protein]; [Progesterone co-treated with Estradiol] results in increased expression of INS1 protein; Progesterone inhibits the reaction [INS1 protein results in increased transport of Glucose]
|
CTD |
PMID:18615583 PMID:21768169 |
|
NCBI chr 1:261,186,119...261,186,686
Ensembl chr 1:261,186,119...261,186,682
|
|
| G
|
Ins2
|
insulin 2
|
decreases expression
|
EXP
|
Progesterone results in decreased expression of INS2 mRNA
|
CTD |
PMID:21770760 |
|
NCBI chr 1:207,272,738...207,421,998
Ensembl chr 1:207,272,742...207,273,805
|
|
| G
|
Insig1
|
insulin induced gene 1
|
increases expression
|
ISO
|
Progesterone results in increased expression of INSIG1 mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr 4:8,049,339...8,057,812
Ensembl chr 4:8,049,556...8,057,778
|
|
| G
|
Insr
|
insulin receptor
|
decreases phosphorylation increases expression multiple interactions
|
EXP ISO
|
Progesterone results in decreased phosphorylation of INSR protein Progesterone results in increased expression of INSR mRNA Progesterone affects the reaction [Streptozocin affects the expression of INSR protein]
|
CTD |
PMID:17068109 PMID:20864642 |
|
NCBI chr12:5,991,135...6,129,275
Ensembl chr12:5,981,835...6,128,803
|
|
| G
|
Insyn1
|
inhibitory synaptic factor 1
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of INSYN1 mRNA
|
CTD |
PMID:21540246 |
|
NCBI chr 8:58,904,153...58,914,850
Ensembl chr 8:67,799,304...67,814,536
|
|
| G
|
Ipo4
|
importin 4
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of IPO4 mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr15:29,117,365...29,127,382
Ensembl chr15:33,087,321...33,097,241
|
|
| G
|
Iqgap2
|
IQ motif containing GTPase activating protein 2
|
increases expression
|
ISO
|
Progesterone results in increased expression of IQGAP2 mRNA
|
CTD |
PMID:21795739 |
|
NCBI chr 2:28,629,558...28,904,649
Ensembl chr 2:28,629,558...28,904,649
|
|
| G
|
Iqgap3
|
IQ motif containing GTPase activating protein 3
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of IQGAP3 mRNA
|
CTD |
PMID:21795739 |
|
NCBI chr 2:175,840,001...175,881,799
Ensembl chr 2:175,839,949...175,881,797
|
|
| G
|
Irak1
|
interleukin-1 receptor-associated kinase 1
|
increases expression
|
ISO
|
Progesterone results in increased expression of IRAK1 mRNA
|
CTD |
PMID:17701593 |
|
NCBI chr X:151,768,621...151,778,521
Ensembl chr X:156,920,081...156,929,825
|
|
| G
|
Irak2
|
interleukin-1 receptor-associated kinase 2
|
increases expression
|
ISO
|
Progesterone results in increased expression of IRAK2 protein Progesterone results in increased expression of IRAK2 mRNA
|
CTD |
PMID:17701593 PMID:21549006 |
|
NCBI chr 4:148,341,704...148,398,211
Ensembl chr 4:148,341,719...148,398,210
|
|
| G
|
Irak3
|
interleukin-1 receptor-associated kinase 3
|
increases expression
|
ISO
|
Progesterone results in increased expression of IRAK3 mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr 7:57,538,522...57,600,166
Ensembl chr 7:57,539,557...57,598,706
|
|
| G
|
Irak4
|
interleukin-1 receptor-associated kinase 4
|
increases expression
|
ISO
|
Progesterone results in increased expression of IRAK4 protein
|
CTD |
PMID:17701593 |
|
NCBI chr 7:127,561,777...127,588,762
Ensembl chr 7:127,561,717...127,597,109
|
|
| G
|
Irf1
|
interferon regulatory factor 1
|
increases expression
|
ISO
|
Progesterone results in increased expression of IRF1 mRNA
|
CTD |
PMID:21549006 |
|
NCBI chr10:38,417,935...38,424,946
Ensembl chr10:38,417,148...38,424,947
|
|
| G
|
Irf6
|
interferon regulatory factor 6
|
increases expression
|
ISO
|
Progesterone results in increased expression of IRF6 mRNA
|
CTD |
PMID:20864642 |
|
NCBI chr13:104,672,179...104,691,386
Ensembl chr13:107,200,731...107,220,049
|
|
| G
|
Irs1
|
insulin receptor substrate 1
|
decreases phosphorylation increases phosphorylation
|
ISO
|
Progesterone results in decreased phosphorylation of IRS1 protein Progesterone results in increased phosphorylation of IRS1 protein
|
CTD |
PMID:15604210 PMID:15949379 |
|
NCBI chr 9:91,001,137...91,053,959
Ensembl chr 9:90,993,519...91,054,538
|
|
| G
|
Irs2
|
insulin receptor substrate 2
|
multiple interactions increases expression increases phosphorylation
|
ISO
|
[Progesterone co-treated with Estradiol] results in increased expression of IRS2 mRNA; Estradiol promotes the reaction [Progesterone results in increased expression of IRS2 mRNA]; Estradiol promotes the reaction [Progesterone results in increased expression of IRS2 protein]; Estradiol promotes the reaction [Progesterone results in increased phosphorylation of IRS2 protein] Progesterone results in increased expression of IRS2 mRNA; Progesterone results in increased expression of IRS2 protein
|
CTD |
PMID:15949379 PMID:17404688 PMID:20864642 PMID:21795739 |
|
NCBI chr16:85,190,310...85,214,543
Ensembl chr16:85,190,111...85,214,543
|
|
| G
|
Irs3
|
insulin receptor substrate 3
|
increases expression
|
EXP
|
Progesterone results in increased expression of IRS3 mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr12:19,053,148...19,055,286
Ensembl chr12:24,689,909...24,692,068
|
|
| G
|
Irx2
|
iroquois homeobox 2
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of IRX2 mRNA
|
CTD |
PMID:18556351 |
|
NCBI chr 1:32,489,512...32,494,930
Ensembl chr 1:32,489,512...32,494,930
|
|
| G
|
Irx4
|
iroquois homeobox 4
|
multiple interactions increases expression
|
ISO
|
[Progesterone co-treated with Estradiol] results in increased expression of IRX4 mRNA Progesterone results in increased expression of IRX4 mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr 1:30,030,561...30,039,549
Ensembl chr 1:31,859,101...31,868,089
|
|
| G
|
Isg20
|
interferon stimulated exonuclease gene 20
|
affects expression
|
ISO
|
Progesterone affects the expression of ISG20 mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr 1:142,234,729...142,246,403
Ensembl chr 1:142,236,137...142,246,401
|
|
| G
|
Ism1
|
isthmin 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of ISM1 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 3:127,023,296...127,102,228
Ensembl chr 3:147,475,533...147,555,908
|
|
| G
|
Isoc1
|
isochorismatase domain containing 1
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of ISOC1 mRNA
|
CTD |
PMID:20864642 |
|
NCBI chr18:54,356,757...54,377,170
Ensembl chr18:54,356,734...54,377,170
|
|
| G
|
Itga1
|
integrin subunit alpha 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of ITGA1 protein; PGR protein affects the reaction [[Estradiol co-treated with Progesterone] results in increased expression of ITGA1]; resveratrol inhibits the reaction [[Estradiol co-treated with Progesterone] results in increased expression of ITGA1 protein]; resveratrol inhibits the reaction [PGR protein affects the reaction [[Estradiol co-treated with Progesterone] results in increased expression of ITGA1]]
|
CTD |
PMID:11507064 |
|
NCBI chr 2:46,646,125...46,812,237
Ensembl chr 2:48,386,249...48,545,284
|
|
| G
|
Itga10
|
integrin subunit alpha 10
|
increases expression
|
ISO
|
Progesterone results in increased expression of ITGA10 mRNA
|
CTD |
PMID:20864642 PMID:21795739 |
|
NCBI chr 2:186,871,711...186,891,012
Ensembl chr 2:186,871,711...186,891,012
|
|
| G
|
Itga2
|
integrin subunit alpha 2
|
multiple interactions decreases expression
|
ISO EXP
|
[Estradiol co-treated with Progesterone] results in decreased expression of ITGA2 mRNA Mifepristone inhibits the reaction [Progesterone results in decreased expression of ITGA2 protein]
|
CTD |
PMID:20660070 PMID:20959644 |
|
NCBI chr 2:48,253,412...48,354,509
Ensembl chr 2:48,253,412...48,354,509
|
|
| G
|
Itga3
|
integrin subunit alpha 3
|
multiple interactions increases expression
|
ISO
|
[Progesterone co-treated with Estradiol] results in increased expression of ITGA3 mRNA Progesterone results in increased expression of ITGA3 mRNA
|
CTD |
PMID:20226447 |
|
NCBI chr10:80,486,998...80,522,548
Ensembl chr10:80,486,999...80,518,901
|
|
| G
|
Itga4
|
integrin subunit alpha 4
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of ITGA4 mRNA
|
CTD |
PMID:21795739 |
|
NCBI chr 3:84,569,487...84,646,276
Ensembl chr 3:84,560,369...84,641,039
|
|
| G
|
Itga5
|
integrin subunit alpha 5
|
multiple interactions increases expression
|
ISO
|
[Progesterone co-treated with Estradiol] results in increased expression of ITGA5 mRNA Progesterone results in increased expression of ITGA5 mRNA
|
CTD |
PMID:20226447 PMID:21795739 |
|
NCBI chr 7:136,358,097...136,381,305
Ensembl chr 7:136,358,097...136,381,305
|
|
| G
|
Itga6
|
integrin subunit alpha 6
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of ITGA6 mRNA
|
CTD |
PMID:20226447 |
|
NCBI chr 3:77,012,168...77,097,076
Ensembl chr 3:77,017,766...77,097,076
|
|
| G
|
Itga7
|
integrin subunit alpha 7
|
increases expression
|
ISO
|
Progesterone results in increased expression of ITGA7 mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr 7:1,944,447...1,973,347
Ensembl chr 7:1,944,460...1,973,339
|
|
| G
|
Itga8
|
integrin subunit alpha 8
|
multiple interactions increases expression
|
ISO EXP
|
[Progesterone co-treated with Estradiol] results in decreased expression of ITGA8 mRNA Progesterone results in increased expression of ITGA8 mRNA
|
CTD |
PMID:20226447 PMID:20726854 |
|
NCBI chr17:80,213,139...80,410,633
Ensembl chr17:80,213,143...80,410,633
|
|
| G
|
Itgam
|
integrin subunit alpha M
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of ITGAM protein
|
CTD |
PMID:21558462 |
|
NCBI chr 1:192,089,496...192,139,947
Ensembl chr 1:192,089,542...192,139,943
|
|
| G
|
Itgb1
|
integrin subunit beta 1
|
increases expression
|
EXP
|
Progesterone results in increased expression of ITGB1 mRNA
|
CTD |
PMID:21770760 |
|
NCBI chr19:73,602,277...73,650,271
Ensembl chr19:73,602,126...73,650,269
|
|
| G
|
Itgb1bp1
|
integrin subunit beta 1 binding protein 1
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of ITGB1BP1 mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr 6:46,549,994...46,564,735
Ensembl chr 6:46,549,999...46,564,398
|
|
| G
|
Itgb2
|
integrin subunit beta 2
|
affects expression increases expression multiple interactions
|
ISO
|
Progesterone affects the expression of ITGB2 mRNA Progesterone results in increased expression of ITGB2 mRNA [Progesterone co-treated with Estradiol] results in increased expression of ITGB2 mRNA
|
CTD |
PMID:17251523 PMID:20226447 PMID:21540246 |
|
NCBI chr20:11,061,009...11,097,242
Ensembl chr20:11,058,492...11,097,182
|
|
| G
|
Itgb3
|
integrin subunit beta 3
|
multiple interactions decreases expression increases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of ITGB3 mRNA; [Progesterone co-treated with Estradiol] results in decreased expression of ITGB3 mRNA; [Progesterone co-treated with Estradiol] results in increased expression of ITGB3 mRNA Progesterone results in decreased expression of ITGB3 mRNA Progesterone results in increased expression of ITGB3 mRNA
|
CTD |
PMID:16403803 PMID:17404688 PMID:20226447 PMID:20660070 |
|
NCBI chr10:90,009,927...90,067,787
Ensembl chr10:90,009,900...90,067,800
|
|
| G
|
Itgb4
|
integrin subunit beta 4
|
multiple interactions increases expression
|
ISO
|
[Progesterone affects the activity of PGR protein alternative form] which affects the expression of ITGB4 mRNA; [Progesterone co-treated with Estradiol] results in decreased expression of ITGB4 mRNA; [Progesterone co-treated with Estradiol] results in increased expression of ITGB4 mRNA Progesterone results in increased expression of ITGB4 mRNA
|
CTD |
PMID:15866122 PMID:20226447 |
|
NCBI chr10:101,705,592...101,741,933
Ensembl chr10:101,705,587...101,741,932
|
|
| G
|
Itgb6
|
integrin subunit beta 6
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of ITGB6 mRNA; [Progesterone co-treated with Estradiol] results in decreased expression of ITGB6 mRNA
|
CTD |
PMID:17404688 PMID:20660070 |
|
NCBI chr 3:65,454,964...65,579,179
Ensembl chr 3:65,456,713...65,530,333
|
|
| G
|
Itgb8
|
integrin subunit beta 8
|
multiple interactions affects expression
|
ISO
|
perfluorooctanoic acid inhibits the reaction [Progesterone affects the expression of ITGB8 mRNA]; Progesterone inhibits the reaction [perfluorooctanoic acid inhibits the reaction [Progesterone affects the expression of ITGB8 mRNA]]
|
CTD |
PMID:31896193 |
|
NCBI chr 6:146,267,982...146,351,245
Ensembl chr 6:146,165,484...146,351,245
|
|
| G
|
Itgbl1
|
integrin subunit beta like 1
|
multiple interactions increases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of ITGBL1 mRNA; [Progesterone co-treated with Estradiol] results in increased expression of ITGBL1 mRNA; Progesterone inhibits the reaction [Estradiol results in decreased expression of ITGBL1 mRNA] Progesterone results in increased expression of ITGBL1 mRNA
|
CTD |
PMID:17404688 PMID:20660070 PMID:21795739 |
|
NCBI chr15:107,186,792...107,448,335
Ensembl chr15:107,186,689...107,451,098
|
|
| G
|
Itm2a
|
integral membrane protein 2A
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of ITM2A mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr X:72,486,383...72,492,344
Ensembl chr X:76,559,181...76,565,437
|
|
| G
|
Itm2c
|
integral membrane protein 2C
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of ITM2C mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr 9:86,545,927...86,559,745
Ensembl chr 9:93,993,895...94,007,704
|
|
| G
|
Itpr1
|
inositol 1,4,5-trisphosphate receptor, type 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of ITPR1 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 4:142,743,401...143,066,505
Ensembl chr 4:142,743,334...143,066,504
|
|
| G
|
Ivd
|
isovaleryl-CoA dehydrogenase
|
increases expression
|
EXP
|
Progesterone results in increased expression of IVD mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr 3:126,305,584...126,326,016
Ensembl chr 3:126,305,364...126,328,160
|
|
| G
|
Ivns1abp
|
influenza virus NS1A binding protein
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of IVNS1ABP mRNA
|
CTD |
PMID:21795739 |
|
NCBI chr13:65,977,069...65,996,685
Ensembl chr13:65,977,045...65,997,547
|
|
| G
|
Jade1
|
jade family PHD finger 1
|
increases expression
|
ISO
|
Progesterone results in increased expression of JADE1 mRNA
|
CTD |
PMID:20864642 PMID:21795739 |
|
NCBI chr 2:126,471,124...126,524,252
Ensembl chr 2:126,471,124...126,524,252
|
|
| G
|
Jak2
|
Janus kinase 2
|
increases expression
|
ISO
|
Progesterone results in increased expression of JAK2 mRNA
|
CTD |
PMID:20864642 |
|
NCBI chr 1:236,408,905...236,468,769
Ensembl chr 1:236,408,662...236,468,762
|
|
| G
|
Jam2
|
junctional adhesion molecule 2
|
increases expression
|
ISO
|
Progesterone results in increased expression of JAM2 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr11:37,316,287...37,366,517
Ensembl chr11:37,317,511...37,367,510
|
|
| G
|
Jchain
|
joining chain of multimeric IgA and IgM
|
affects expression
|
ISO
|
Progesterone affects the expression of JCHAIN mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr14:19,822,976...19,831,072
Ensembl chr14:19,822,976...19,838,307
|
|
| G
|
Jdp2
|
Jun dimerization protein 2
|
increases expression multiple interactions
|
ISO
|
Progesterone results in increased expression of JDP2 mRNA [Estradiol co-treated with Progesterone] results in increased expression of JDP2 mRNA
|
CTD |
PMID:18037150 PMID:18556351 |
|
NCBI chr 6:110,988,927...111,033,392
Ensembl chr 6:110,992,806...111,033,392
|
|
| G
|
Jmy
|
junction mediating and regulatory protein, p53 cofactor
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of JMY mRNA
|
CTD |
PMID:21795739 |
|
NCBI chr 2:24,662,104...24,730,955
Ensembl chr 2:26,409,969...26,465,649
|
|
| G
|
Jun
|
Jun proto-oncogene, AP-1 transcription factor subunit
|
multiple interactions increases expression decreases expression
|
EXP ISO
|
[Estrogens co-treated with Progesterone] results in increased phosphorylation of JUN protein; Progesterone promotes the reaction [Hydrogen Peroxide results in increased activity of JUN protein] Progesterone results in increased expression of JUN mRNA Progesterone results in decreased expression of JUN mRNA
|
CTD |
PMID:16284289 PMID:17170212 PMID:21258428 PMID:21549006 |
|
NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:114,973,151...115,013,285
|
|
| G
|
Jund
|
JunD proto-oncogene, AP-1 transcription factor subunit
|
increases expression
|
ISO
|
Progesterone results in increased expression of JUND mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr16:18,768,093...18,769,771
Ensembl chr16:18,764,985...18,782,148
|
|
| G
|
Jup
|
junction plakoglobin
|
affects expression multiple interactions
|
ISO
|
Progesterone affects the expression of JUP mRNA [Estradiol co-treated with Progesterone] results in decreased expression of JUP mRNA
|
CTD |
PMID:17251523 PMID:20660070 |
|
NCBI chr10:85,800,812...85,827,881
Ensembl chr10:85,800,814...85,827,429
|
|
| G
|
Kansl1l
|
KAT8 regulatory NSL complex subunit 1-like
|
increases expression
|
ISO
|
Progesterone results in increased expression of KANSL1L mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr 9:75,660,865...75,766,730
Ensembl chr 9:75,661,233...75,766,745
|
|
| G
|
Kazald1
|
Kazal-type serine peptidase inhibitor domain 1
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of KAZALD1 mRNA
|
CTD |
PMID:21540246 |
|
NCBI chr 1:253,888,639...253,892,211
Ensembl chr 1:253,888,783...253,892,305
|
|
| G
|
Kazn
|
kazrin, periplakin interacting protein
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of KAZN mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 5:159,675,803...160,666,084
Ensembl chr 5:159,675,803...160,664,154
|
|
| G
|
Kbtbd11
|
kelch repeat and BTB domain containing 11
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in increased expression of KBTBD11 mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr16:81,318,596...81,340,334
Ensembl chr16:81,313,093...81,340,390
|
|
| G
|
Kcna5
|
potassium voltage-gated channel subfamily A member 5
|
decreases activity
|
ISO
|
Progesterone results in decreased activity of KCNA5 protein
|
CTD |
PMID:18068743 |
|
NCBI chr 4:159,354,689...159,358,173
Ensembl chr 4:160,996,950...161,044,408
|
|
| G
|
Kcnd2
|
potassium voltage-gated channel subfamily D member 2
|
multiple interactions increases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of KCND2 mRNA Progesterone results in increased expression of KCND2 mRNA
|
CTD |
PMID:20660070 PMID:22238285 |
|
NCBI chr 4:49,775,812...50,277,746
Ensembl chr 4:50,742,839...51,243,522
|
|
| G
|
Kcnd3
|
potassium voltage-gated channel subfamily D member 3
|
increases expression
|
ISO
|
Progesterone results in increased expression of KCND3 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 2:195,626,316...195,843,690
Ensembl chr 2:195,626,316...195,843,690
|
|
| G
|
Kcne1
|
potassium voltage-gated channel subfamily E regulatory subunit 1
|
increases expression
|
EXP
|
Progesterone results in increased expression of KCNE1 mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr11:45,066,875...45,080,024
Ensembl chr11:45,064,162...45,081,247
|
|
| G
|
Kcne3
|
potassium voltage-gated channel subfamily E regulatory subunit 3
|
multiple interactions decreases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of KCNE3 mRNA Progesterone results in decreased expression of KCNE3 mRNA
|
CTD |
PMID:20660070 PMID:22238285 |
|
NCBI chr 1:163,936,035...163,942,998
Ensembl chr 1:163,935,991...163,950,162
|
|
| G
|
Kcne4
|
potassium voltage-gated channel subfamily E regulatory subunit 4
|
multiple interactions increases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of KCNE4 mRNA Progesterone results in increased expression of KCNE4 mRNA
|
CTD |
PMID:20660070 PMID:21795739 |
|
NCBI chr 9:87,674,264...87,699,088
Ensembl chr 9:87,650,462...87,704,131
|
|
| G
|
Kcng1
|
potassium voltage-gated channel modifier subfamily G member 1
|
multiple interactions increases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of KCNG1 mRNA; [Progesterone co-treated with Estradiol] results in increased expression of KCNG1 mRNA Progesterone results in increased expression of KCNG1 mRNA
|
CTD |
PMID:17404688 PMID:20660070 PMID:21795739 |
|
NCBI chr 3:156,960,717...156,992,877
Ensembl chr 3:177,392,031...177,411,507
|
|
| G
|
Kcnh2
|
potassium voltage-gated channel subfamily H member 2
|
multiple interactions
|
EXP
|
2-Hydroxypropyl-beta-cyclodextrin inhibits the reaction [Progesterone results in decreased localization of KCNH2 protein]; E 4031 inhibits the reaction [Progesterone results in decreased localization of KCNH2 protein]; Progesterone results in decreased glycosylation of and results in decreased localization of and results in decreased activity of KCNH2 protein
|
CTD |
PMID:21525004 |
|
NCBI chr 4:11,719,357...11,751,424
Ensembl chr 4:11,692,980...11,751,421
|
|
| G
|
Kcnip4
|
potassium voltage-gated channel interacting protein 4
|
increases expression
|
ISO
|
Progesterone results in increased expression of KCNIP4 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr14:65,593,297...66,743,994
Ensembl chr14:65,593,366...66,743,993
|
|
| G
|
Kcnj13
|
potassium inwardly-rectifying channel, subfamily J, member 13
|
decreases expression
|
EXP
|
Progesterone results in decreased expression of KCNJ13 mRNA
|
CTD |
PMID:21770760 |
|
NCBI chr 9:95,509,228...95,528,400
Ensembl chr 9:95,510,877...95,520,817
|
|
| G
|
Kcnj16
|
potassium inwardly-rectifying channel, subfamily J, member 16
|
increases expression
|
ISO
|
Progesterone results in increased expression of KCNJ16 mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr10:96,489,329...96,520,745
Ensembl chr10:96,460,331...96,566,075
|
|
| G
|
Kcnj8
|
potassium inwardly-rectifying channel, subfamily J, member 8
|
multiple interactions increases expression
|
ISO
|
[Progesterone co-treated with Estradiol] results in increased expression of KCNJ8 mRNA Progesterone results in increased expression of KCNJ8 mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr 4:177,240,692...177,246,548
Ensembl chr 4:177,239,908...177,246,531
|
|
| G
|
Kcnk3
|
potassium two pore domain channel subfamily K member 3
|
decreases expression increases expression
|
ISO EXP
|
Progesterone results in decreased expression of KCNK3 mRNA Progesterone results in increased expression of KCNK3 mRNA
|
CTD |
PMID:18070364 PMID:20726854 |
|
NCBI chr 6:31,483,129...31,519,061
Ensembl chr 6:31,483,140...31,519,061
|
|
| G
|
Kcnk6
|
potassium two pore domain channel subfamily K member 6
|
increases expression
|
ISO
|
Progesterone results in increased expression of KCNK6 mRNA
|
CTD |
PMID:20864642 |
|
NCBI chr 1:93,652,888...93,661,419
|
|
| G
|
Kcnma1
|
potassium calcium-activated channel subfamily M alpha 1
|
multiple interactions increases expression decreases activity
|
ISO EXP
|
[Estradiol co-treated with Progesterone] results in increased expression of KCNMA1 mRNA; Progesterone inhibits the reaction [Estradiol results in increased activity of KCNMA1 protein] Progesterone results in increased expression of KCNMA1 mRNA; Progesterone results in increased expression of KCNMA1 protein Progesterone results in decreased activity of KCNMA1 protein Progesterone results in increased expression of KCNMA1 mRNA; Progesterone results in increased expression of KCNMA1 mRNA alternative form
|
CTD |
PMID:16102753 PMID:18068743 PMID:20660070 PMID:21795739 |
|
NCBI chr15:351,065...1,057,117
Ensembl chr15:351,659...1,057,117
|
|
| G
|
Kcnmb2
|
potassium calcium-activated channel subfamily M regulatory beta subunit 2
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of KCNMB2 mRNA
|
CTD |
PMID:21795739 |
|
NCBI chr 2:114,670,027...114,975,374
Ensembl chr 2:116,599,387...116,903,854
|
|
| G
|
Kcnn4
|
potassium calcium-activated channel subfamily N member 4
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of KCNN4 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 1:89,084,306...89,102,279
Ensembl chr 1:89,086,814...89,102,275
|
|
| G
|
Kcns3
|
potassium voltage-gated channel, modifier subfamily S, member 3
|
increases expression
|
ISO
|
Progesterone results in increased expression of KCNS3 mRNA
|
CTD |
PMID:21795739 |
|
NCBI chr 6:33,808,314...33,865,018
Ensembl chr 6:39,523,777...39,618,848
|
|
| G
|
Kcnt2
|
potassium sodium-activated channel subfamily T member 2
|
increases expression
|
ISO
|
Progesterone results in increased expression of KCNT2 mRNA
|
CTD |
PMID:21795739 |
|
NCBI chr13:54,214,831...54,609,889
Ensembl chr13:54,215,307...54,607,924
|
|
| G
|
Kctd12
|
potassium channel tetramerization domain containing 12
|
increases expression
|
ISO
|
Progesterone results in increased expression of KCTD12 mRNA
|
CTD |
PMID:21795739 PMID:22238285 |
|
NCBI chr15:86,214,786...86,220,725
Ensembl chr15:86,214,840...86,224,539
|
|
| G
|
Kdm4a
|
lysine demethylase 4A
|
increases expression
|
ISO
|
Progesterone results in increased expression of KDM4A mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr 5:131,672,754...131,719,534
Ensembl chr 5:136,958,178...137,004,951
|
|
| G
|
Kdr
|
kinase insert domain receptor
|
increases expression
|
EXP ISO
|
Progesterone results in increased expression of KDR mRNA
|
CTD |
PMID:18692832 PMID:20726854 |
|
NCBI chr14:32,572,031...32,615,204
Ensembl chr14:32,572,049...32,615,192
|
|
| G
|
Kdsr
|
3-ketodihydrosphingosine reductase
|
increases expression
|
ISO
|
Progesterone results in increased expression of KDSR mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr13:23,374,101...23,408,779
Ensembl chr13:23,376,779...23,408,897
|
|
| G
|
Khdrbs1
|
KH RNA binding domain containing, signal transduction associated 1
|
affects expression
|
ISO
|
Progesterone affects the expression of KHDRBS1 mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr 5:147,337,048...147,374,604
Ensembl chr 5:147,347,904...147,373,448
|
|
| G
|
Kif13b
|
kinesin family member 13B
|
increases expression
|
ISO
|
Progesterone results in increased expression of KIF13B mRNA
|
CTD |
PMID:21795739 |
|
NCBI chr15:43,084,059...43,241,719
Ensembl chr15:43,080,910...43,241,719
|
|
| G
|
Kif14
|
kinesin family member 14
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of KIF14 mRNA
|
CTD |
PMID:21795739 |
|
NCBI chr13:50,478,646...50,542,256
Ensembl chr13:50,478,721...50,542,248
|
|
| G
|
Kif20a
|
kinesin family member 20A
|
increases expression decreases expression
|
ISO
|
Progesterone results in increased expression of KIF20A mRNA Progesterone results in decreased expression of KIF20A mRNA
|
CTD |
PMID:18070364 PMID:21795739 |
|
NCBI chr18:26,504,422...26,512,908
Ensembl chr18:26,504,072...26,512,909
|
|
| G
|
Kif4a
|
kinesin family member 4A
|
increases expression decreases expression
|
ISO
|
Progesterone results in increased expression of KIF4A mRNA Progesterone results in decreased expression of KIF4A mRNA
|
CTD |
PMID:18070364 PMID:21795739 |
|
NCBI chr X:69,761,803...69,864,335
Ensembl chr X:69,761,883...69,864,335
|
|
| G
|
Kiss1
|
KiSS-1 metastasis-suppressor
|
multiple interactions increases abundance
|
EXP
|
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [KISS1 protein results in increased abundance of Progesterone]; KISS1 protein promotes the reaction [CGB3 protein results in increased abundance of Progesterone]
|
CTD |
PMID:23312234 |
|
NCBI chr13:44,775,106...44,780,707
Ensembl chr13:47,327,004...47,332,906
|
|
| G
|
Kiz
|
kizuna centrosomal protein
|
increases expression
|
ISO
|
Progesterone results in increased expression of KIZ mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr 3:154,730,873...154,838,410
Ensembl chr 3:154,730,634...154,838,410
|
|
| G
|
Klf10
|
KLF transcription factor 10
|
decreases expression
|
ISO EXP
|
Progesterone results in decreased expression of KLF10 mRNA
|
CTD |
PMID:18037150 PMID:20726854 |
|
NCBI chr 7:71,352,612...71,358,680
Ensembl chr 7:71,350,573...71,358,948
|
|
| G
|
Klf15
|
KLF transcription factor 15
|
increases expression
|
EXP
|
Progesterone results in increased expression of KLF15 mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr 4:124,522,652...124,535,613
Ensembl chr 4:124,522,909...124,542,373
|
|
| G
|
Klf4
|
KLF transcription factor 4
|
multiple interactions
|
ISO
|
Progesterone promotes the reaction [Estradiol results in increased expression of KLF4 mRNA]
|
CTD |
PMID:21795739 |
|
NCBI chr 5:75,074,107...75,079,182
Ensembl chr 5:75,074,236...75,078,592
|
|
| G
|
Klf5
|
KLF transcription factor 5
|
increases expression multiple interactions affects expression
|
ISO
|
Progesterone results in increased expression of KLF5 mRNA perfluorooctanoic acid inhibits the reaction [Progesterone affects the expression of KLF5 mRNA]; Progesterone inhibits the reaction [perfluorooctanoic acid inhibits the reaction [Progesterone affects the expression of KLF5 mRNA]]
|
CTD |
PMID:18037150 PMID:18070364 PMID:31896193 |
|
NCBI chr15:82,472,081...82,487,267
Ensembl chr15:82,472,065...82,487,262
|
|
| G
|
Klf6
|
KLF transcription factor 6
|
increases expression
|
ISO
|
Progesterone results in increased expression of KLF6 mRNA
|
CTD |
PMID:18070364 PMID:20864642 PMID:21795739 |
|
NCBI chr17:69,449,483...69,458,478
Ensembl chr17:69,441,493...69,498,601
|
|
| G
|
Klf9
|
KLF transcription factor 9
|
increases expression
|
EXP
|
Progesterone results in increased expression of KLF9 mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr 1:230,126,646...230,151,641
Ensembl chr 1:230,126,646...230,151,641
|
|
| G
|
Klhl14
|
kelch-like family member 14
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of KLHL14 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr18:12,804,253...12,917,828
Ensembl chr18:13,079,159...13,193,557
|
|
| G
|
Klhl24
|
kelch-like family member 24
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of KLHL24 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr11:94,348,024...94,382,085
Ensembl chr11:94,351,157...94,382,050
|
|
| G
|
Klhl29
|
kelch-like family member 29
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of KLHL29 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 6:33,805,922...34,110,055
Ensembl chr 6:33,805,922...34,110,055
|
|
| G
|
Klhl31
|
kelch-like family member 31
|
multiple interactions decreases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of KLHL31 mRNA Progesterone results in decreased expression of KLHL31 mRNA
|
CTD |
PMID:20660070 PMID:22238285 |
|
NCBI chr 8:87,395,878...87,419,236
Ensembl chr 8:87,395,869...87,419,258
|
|
| G
|
Klk10
|
kallikrein related-peptidase 10
|
multiple interactions
|
ISO
|
[Estrogens co-treated with Progesterone] results in increased expression of KLK10 mRNA
|
CTD |
PMID:20686372 |
|
NCBI chr 1:103,371,638...103,375,918
Ensembl chr 1:103,371,638...103,375,918
|
|
| G
|
Klk11
|
kallikrein related-peptidase 11
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of KLK11 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 1:94,228,741...94,233,281
Ensembl chr 1:103,365,290...103,369,830
|
|
| G
|
Klk5
|
kallikrein related-peptidase 5
|
multiple interactions
|
ISO
|
[Progesterone results in increased activity of PGR protein] which results in increased expression of KLK5 mRNA
|
CTD |
PMID:15845616 |
|
NCBI chr 1:94,296,574...94,304,768
Ensembl chr 1:103,433,065...103,441,305
|
|
| G
|
Klk6
|
kallikrein related-peptidase 6
|
multiple interactions
|
ISO
|
[Progesterone results in increased activity of PGR protein] which results in increased expression of KLK6 mRNA
|
CTD |
PMID:15845616 |
|
NCBI chr 1:94,278,863...94,286,136
Ensembl chr 1:103,416,886...103,422,690
|
|
| G
|
Klrb1a
|
killer cell lectin like receptor B1A
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of KLRB1 mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr 4:163,576,672...163,590,201
Ensembl chr 4:163,576,672...163,619,374
|
|
| G
|
Klrc3
|
killer cell lectin like receptor C3
|
multiple interactions increases expression
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of KLRC3 mRNA Progesterone results in increased expression of KLRC3 mRNA
|
CTD |
PMID:17404688 PMID:21540246 |
|
NCBI chr 4:163,105,081...163,112,737
Ensembl chr 4:164,791,128...164,798,758
|
|
| G
|
Kng1
|
kininogen 1
|
increases expression
|
EXP
|
Progesterone results in increased expression of KNG1 mRNA
|
CTD |
PMID:21770760 |
|
NCBI chr11:91,317,354...91,340,148
Ensembl chr11:91,317,355...91,340,148
|
|
| G
|
Knl1
|
kinetochore scaffold 1
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of KNL1 mRNA
|
CTD |
PMID:21795739 |
|
NCBI chr 3:126,483,498...126,545,774
Ensembl chr 3:126,483,544...126,545,774
|
|
| G
|
Krt12
|
keratin 12
|
increases expression
|
ISO
|
Progesterone results in increased expression of KRT12 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr10:84,370,803...84,378,103
Ensembl chr10:84,866,965...84,874,265
|
|
| G
|
Krt15
|
keratin 15
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of KRT15 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr10:85,567,197...85,571,014
Ensembl chr10:85,567,202...85,571,142
|
|
| G
|
Krt17
|
keratin 17
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of KRT17 mRNA
|
CTD |
PMID:18037150 PMID:22238285 |
|
NCBI chr10:85,178,673...85,183,392
Ensembl chr10:85,679,070...85,683,787
|
|
| G
|
Krt18
|
keratin 18
|
multiple interactions decreases expression
|
ISO
|
NCOA2 protein affects the reaction [Progesterone results in decreased expression of KRT18 mRNA]
|
CTD |
PMID:17556502 PMID:21795739 |
|
NCBI chr 7:133,157,486...133,161,162
Ensembl chr 7:135,035,982...135,039,848 Ensembl chr10:135,035,982...135,039,848
|
|
| G
|
Krt23
|
keratin 23
|
multiple interactions decreases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of KRT23 mRNA; [Progesterone co-treated with Estradiol] results in decreased expression of KRT23 mRNA Progesterone results in decreased expression of KRT23 mRNA
|
CTD |
PMID:17404688 PMID:20660070 PMID:21540246 |
|
NCBI chr10:84,930,603...84,946,929
Ensembl chr10:84,930,603...84,946,929
|
|
| G
|
Krt34
|
keratin 34
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of KRT34 mRNA
|
CTD |
PMID:20864642 |
|
NCBI chr10:84,969,988...84,974,098
Ensembl chr10:85,470,391...85,474,501
|
|
| G
|
Krt7
|
keratin 7
|
increases expression
|
ISO
|
Progesterone results in increased expression of KRT7 mRNA
|
CTD |
PMID:18497975 |
|
NCBI chr 7:134,407,626...134,423,787
Ensembl chr 7:134,407,584...134,423,786
|
|
| G
|
Krt8
|
keratin 8
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of KRT8 mRNA
|
CTD |
PMID:21540246 |
|
NCBI chr 7:135,002,886...135,010,339
Ensembl chr 7:135,002,894...135,010,403
|
|
| G
|
Krt86
|
keratin 86
|
increases expression
|
ISO
|
Progesterone results in increased expression of KRT86 mRNA
|
CTD |
PMID:21540246 |
|
NCBI chr 7:132,591,489...132,598,142
Ensembl chr 7:134,470,224...134,476,873
|
|
| G
|
Krtcap3
|
keratinocyte associated protein 3
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of KRTCAP3 mRNA
|
CTD |
PMID:21540246 |
|
NCBI chr 6:30,840,906...30,842,500
Ensembl chr 6:30,840,906...30,842,475
|
|
| G
|
Kynu
|
kynureninase
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of KYNU mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 3:27,778,646...27,929,470
Ensembl chr 3:48,188,182...48,339,014
|
|
| G
|
L1cam
|
L1 cell adhesion molecule
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of L1CAM mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr X:156,748,597...156,775,116
Ensembl chr X:156,748,597...156,775,077
|
|
| G
|
L2hgdh
|
L-2-hydroxyglutarate dehydrogenase
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of L2HGDH mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 6:93,900,427...93,941,534
Ensembl chr 6:93,900,427...93,941,534
|
|
| G
|
Lama2
|
laminin subunit alpha 2
|
increases expression
|
ISO
|
Progesterone results in increased expression of LAMA2 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 1:19,492,126...20,140,056
Ensembl chr 1:19,244,599...20,140,056
|
|
| G
|
Lama3
|
laminin subunit alpha 3
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of LAMA3 mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr18:3,797,898...4,033,021
Ensembl chr18:3,797,939...4,026,449
|
|
| G
|
Lama4
|
laminin subunit alpha 4
|
multiple interactions increases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of LAMA4 mRNA Progesterone results in increased expression of LAMA4 mRNA
|
CTD |
PMID:20660070 PMID:21540246 |
|
NCBI chr20:42,392,268...42,533,347
Ensembl chr20:43,946,898...44,087,972
|
|
| G
|
Lamb3
|
laminin subunit beta 3
|
multiple interactions increases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of LAMB3 mRNA; [Progesterone co-treated with Estradiol] results in increased expression of LAMB3 mRNA Progesterone results in increased expression of LAMB3 mRNA
|
CTD |
PMID:20226447 PMID:20660070 |
|
NCBI chr13:107,362,514...107,404,081
Ensembl chr13:107,322,526...107,404,081
|
|
| G
|
Lamc1
|
laminin subunit gamma 1
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in increased expression of LAMC1 mRNA
|
CTD |
PMID:20226447 |
|
NCBI chr13:67,924,872...68,051,986
Ensembl chr13:67,924,872...68,051,986
|
|
| G
|
Lamc2
|
laminin subunit gamma 2
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of LAMC2 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr13:67,835,199...67,894,694
Ensembl chr13:67,835,199...67,895,102
|
|
| G
|
Lamc3
|
laminin subunit gamma 3
|
increases expression
|
ISO
|
Progesterone results in increased expression of LAMC3 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 3:15,165,220...15,226,697
Ensembl chr 3:35,562,713...35,624,460
|
|
| G
|
Large2
|
LARGE xylosyl- and glucuronyltransferase 2
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of LARGE2 mRNA
|
CTD |
PMID:21540246 |
|
NCBI chr 3:98,791,543...98,800,251
Ensembl chr 3:98,791,543...98,797,782
|
|
| G
|
Larp4
|
La ribonucleoprotein 4
|
increases expression
|
ISO
|
Progesterone results in increased expression of LARP4 mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr 7:131,104,470...131,152,692
Ensembl chr 7:132,980,385...133,029,633
|
|
| G
|
Lbp
|
lipopolysaccharide binding protein
|
increases expression
|
ISO
|
Progesterone results in increased expression of LBP mRNA
|
CTD |
PMID:21540246 |
|
NCBI chr 3:167,373,786...167,400,941
Ensembl chr 3:167,373,924...167,401,518
|
|
| G
|
Lce3e
|
late cornified envelope 3E
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of LCE3B mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 2:178,578,488...178,579,661
Ensembl chr 2:181,274,092...181,275,265
|
|
| G
|
Lck
|
LCK proto-oncogene, Src family tyrosine kinase
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of LCK mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr 5:147,172,642...147,201,267
Ensembl chr 5:147,172,642...147,201,267
|
|
| G
|
Lcn2
|
lipocalin 2
|
affects expression
|
ISO
|
Progesterone affects the expression of LCN2 mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr 3:36,078,432...36,081,851
Ensembl chr 3:36,078,436...36,081,842
|
|
| G
|
Lcp1
|
lymphocyte cytosolic protein 1
|
increases expression
|
ISO
|
Progesterone results in increased expression of LCP1 mRNA
|
CTD |
PMID:20864642 PMID:21540246 |
|
NCBI chr15:56,846,375...56,954,090
Ensembl chr15:56,847,433...56,954,092
|
|
| G
|
Lct
|
lactase
|
increases expression
|
ISO
|
Progesterone results in increased expression of LCT mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr13:42,334,347...42,376,872
Ensembl chr13:42,334,347...42,376,872
|
|
| G
|
Ldb2
|
LIM domain binding 2
|
decreases expression increases expression multiple interactions
|
ISO
|
Progesterone results in decreased expression of LDB2 mRNA Progesterone results in increased expression of LDB2 mRNA NCOA2 protein affects the reaction [Progesterone results in decreased expression of LDB2 mRNA]
|
CTD |
PMID:17556502 PMID:22238285 |
|
NCBI chr14:70,489,243...70,810,573
Ensembl chr14:70,489,620...70,810,574
|
|
| G
|
Ldha
|
lactate dehydrogenase A
|
decreases expression increases expression
|
ISO EXP
|
Progesterone results in decreased expression of LDHA mRNA Progesterone results in increased expression of LDHA mRNA
|
CTD |
PMID:18037150 PMID:21770760 |
|
NCBI chr 1:106,508,092...106,517,512
Ensembl chr 1:106,502,182...106,517,521
|
|
| G
|
Ldhb
|
lactate dehydrogenase B
|
increases expression
|
EXP
|
Progesterone results in increased expression of LDHB mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr 4:177,159,389...177,177,408
Ensembl chr 4:177,159,392...177,177,408
|
|
| G
|
Ldlr
|
low density lipoprotein receptor
|
affects expression increases expression
|
ISO EXP
|
Progesterone affects the expression of LDLR mRNA Progesterone results in increased expression of LDLR mRNA
|
CTD |
PMID:17170212 PMID:17251523 PMID:18037150 PMID:18070364 |
|
NCBI chr 8:28,546,191...28,569,075
Ensembl chr 8:28,546,146...28,570,675
|
|
| G
|
Ldlrad4
|
low density lipoprotein receptor class A domain containing 4
|
increases expression
|
ISO
|
Progesterone results in increased expression of LDLRAD4 mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr18:61,519,253...61,848,403
Ensembl chr18:63,790,440...64,113,064
|
|
| G
|
Lefty1
|
left right determination factor 1
|
increases expression multiple interactions
|
ISO
|
Progesterone results in increased expression of LEFTY1 mRNA [Progesterone co-treated with Triclosan] results in increased expression of LEFTY1 mRNA
|
CTD |
PMID:26604029 |
|
NCBI chr13:95,188,091...95,191,488
Ensembl chr13:95,188,091...95,191,488
|
|
| G
|
Lemd1
|
LEM domain containing 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of LEMD1 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr13:43,631,705...43,697,765
Ensembl chr13:46,218,085...46,250,562
|
|
| G
|
Lep
|
leptin
|
decreases secretion multiple interactions increases expression
|
ISO
|
Progesterone results in decreased secretion of LEP protein LEP protein inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased chemical synthesis of Progesterone]; LEPR protein affects the reaction [LEP protein inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased chemical synthesis of Progesterone]] Progesterone results in increased expression of LEP mRNA
|
CTD |
PMID:15713686 PMID:16048798 PMID:19849856 |
|
NCBI chr 4:58,626,529...58,640,663
Ensembl chr 4:58,626,523...58,640,661
|
|
| G
|
Lepr
|
leptin receptor
|
multiple interactions
|
ISO
|
LEPR protein affects the reaction [LEP protein inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased chemical synthesis of Progesterone]]
|
CTD |
PMID:19849856 |
|
NCBI chr 5:121,409,735...121,593,201
Ensembl chr 5:121,474,099...121,591,215
|
|
| G
|
Lfng
|
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of LFNG mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr12:19,144,474...19,152,951
Ensembl chr12:19,124,662...19,152,918
|
|
| G
|
Lgals1
|
galectin 1
|
affects metabolic processing
|
ISO
|
LGALS1 protein affects the metabolism of Progesterone
|
CTD |
PMID:17242467 |
|
NCBI chr 7:112,365,695...112,368,801
Ensembl chr 7:112,361,850...112,368,800
|
|
| G
|
Lgals3
|
galectin 3
|
affects metabolic processing multiple interactions
|
ISO
|
LGALS3 protein affects the metabolism of Progesterone [Estradiol co-treated with Progesterone] results in decreased expression of LGALS3 mRNA
|
CTD |
PMID:17242467 PMID:20660070 |
|
NCBI chr15:23,099,795...23,111,731
Ensembl chr15:23,086,841...23,111,737
|
|
| G
|
Lgals8
|
galectin 8
|
increases expression
|
ISO
|
Progesterone results in increased expression of LGALS8 mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr17:58,024,652...58,052,764
Ensembl chr17:62,719,828...62,744,482
|
|
| G
|
Lgalsl
|
galectin-like
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of LGALSL mRNA
|
CTD |
PMID:20864642 |
|
NCBI chr14:99,198,340...99,205,846
Ensembl chr14:99,198,339...99,206,487
|
|
| G
|
Lgi1
|
leucine-rich, glioma inactivated 1
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of LGI1 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 1:236,043,269...236,084,617
Ensembl chr 1:245,455,599...245,499,095
|
|
| G
|
Lgr5
|
leucine rich repeat containing G protein coupled receptor 5
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of LGR5 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 7:52,973,151...53,107,964
Ensembl chr 7:52,974,332...53,108,163
|
|
| G
|
Lhb
|
luteinizing hormone subunit beta
|
multiple interactions increases chemical synthesis increases abundance increases secretion decreases abundance
|
EXP ISO
|
2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane inhibits the reaction [CGB3 protein results in increased chemical synthesis of Progesterone]; 7-Ala-angiotensin (1-7) inhibits the reaction [LHB protein results in increased secretion of Progesterone]; [Estradiol co-treated with Progesterone] results in decreased secretion of LHB protein; [Estradiol co-treated with Progesterone] results in increased expression of LHB protein; [FSHB protein co-treated with CGB3 protein] inhibits the reaction [Puromycin Aminonucleoside results in decreased abundance of Progesterone]; Atrazine inhibits the reaction [[estradiol 3-benzoate co-treated with Progesterone] results in increased secretion of LHB protein]; KISS1 protein promotes the reaction [CGB3 protein results in increased abundance of Progesterone]; nociceptin (1-13) amide inhibits the reaction [PNOC protein inhibits the reaction [[Estradiol co-treated with Progesterone] results in increased expression of LHB protein]]; PNOC protein inhibits the reaction [[Estradiol co-treated with Progesterone] results in increased expression of LHB protein] LHB protein results in increased abundance of Progesterone LHB protein results in decreased abundance of Progesterone [estradiol 3-benzoate co-treated with Progesterone] results in increased abundance of LHB protein; mono-(2-ethylhexyl)phthalate inhibits the reaction [LHB protein results in increased secretion of Progesterone]; Reactive Oxygen Species promotes the reaction [LHB protein results in increased abundance of Progesterone] [LHB protein affects the secretion of Cyclic AMP] which results in increased secretion of Progesterone; ADCYAP1R1 protein promotes the reaction [LHB protein results in increased abundance of Progesterone]; DDT inhibits the reaction [LHB protein results in increased secretion of Progesterone]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [LHB protein results in increased secretion of Progesterone]
|
CTD |
PMID:15056801 PMID:15525572 PMID:15967414 PMID:16574160 PMID:17640482 PMID:19215433 PMID:19926922 PMID:21220312 PMID:21664964 PMID:22247282 PMID:22577852 PMID:23071612 PMID:23312234 PMID:23433069 PMID:33638691 PMID:34627990 More...
|
|
NCBI chr 1:105,037,457...105,038,446
Ensembl chr 1:105,037,457...105,038,445
|
|
| G
|
Lhfpl6
|
LHFPL tetraspan subfamily member 6
|
increases expression
|
ISO
|
Progesterone results in increased expression of LHFPL6 mRNA
|
CTD |
PMID:20864642 PMID:21540246 |
|
NCBI chr 2:137,126,485...137,324,442
Ensembl chr 2:139,276,789...139,474,737
|
|
| G
|
Lif
|
LIF, interleukin 6 family cytokine
|
affects expression multiple interactions increases expression affects response to substance
|
ISO
|
Progesterone affects the expression of LIF; Progesterone affects the expression of LIF mRNA [Estradiol co-treated with Progesterone] results in increased expression of LIF mRNA; [NR5A1 protein co-treated with LIF protein co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with Tretinoin] results in increased abundance of Progesterone; [Progesterone co-treated with Estradiol] affects the expression of LIF; ESR1 protein promotes the reaction [[Estradiol co-treated with Progesterone] results in increased expression of LIF mRNA]; LIF protein affects the reaction [Progesterone inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased abundance of Nitric Oxide]] [Estradiol co-treated with Progesterone] results in decreased expression of LIF mRNA Progesterone results in increased expression of LIF mRNA LIF protein affects the susceptibility to Progesterone
|
CTD |
PMID:15639816 PMID:17307916 PMID:20660070 PMID:21610156 PMID:23407384 PMID:23409146 PMID:25210133 More...
|
|
NCBI chr14:83,354,602...83,364,053
Ensembl chr14:83,358,164...83,364,053
|
|
| G
|
Lifr
|
LIF receptor subunit alpha
|
increases expression
|
EXP
|
Progesterone results in increased expression of LIFR mRNA
|
CTD |
PMID:21770760 |
|
NCBI chr 2:57,951,787...58,020,357
Ensembl chr 2:57,952,975...58,020,364
|
|
| G
|
Lig1
|
DNA ligase 1
|
decreases expression
|
ISO EXP
|
Progesterone results in decreased expression of LIG1 mRNA
|
CTD |
PMID:16966611 PMID:20726854 |
|
NCBI chr 1:83,243,043...83,281,707
Ensembl chr 1:83,219,545...83,281,708
|
|
| G
|
Lima1
|
LIM domain and actin binding 1
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of LIMA1 mRNA
|
CTD |
PMID:18037150 PMID:20864642 |
|
NCBI chr 7:132,780,556...132,880,343
Ensembl chr 7:132,780,556...132,880,386
|
|
| G
|
Lin7b
|
lin-7 homolog B, crumbs cell polarity complex component
|
increases expression
|
ISO
|
Progesterone results in increased expression of LIN7B mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 1:104,983,368...104,986,795
Ensembl chr 1:104,982,771...104,986,078
|
|
| G
|
Lipa
|
lipase A, lysosomal acid type
|
increases expression
|
EXP
|
Progesterone results in increased expression of LIPA mRNA
|
CTD |
PMID:21770760 |
|
NCBI chr 1:241,437,524...241,470,936
Ensembl chr 1:241,437,524...241,470,740
|
|
| G
|
Lipg
|
lipase G, endothelial type
|
increases expression
|
ISO
|
Progesterone results in increased expression of LIPG mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr18:70,790,077...70,811,259
Ensembl chr18:70,790,077...70,812,260
|
|
| G
|
Lmcd1
|
LIM and cysteine-rich domains 1
|
increases expression multiple interactions
|
ISO
|
Progesterone results in increased expression of LMCD1 mRNA [Estradiol co-treated with Progesterone] results in increased expression of LMCD1 mRNA
|
CTD |
PMID:17404688 PMID:20660070 PMID:21795739 |
|
NCBI chr 4:146,948,993...147,007,878
Ensembl chr 4:146,948,958...147,007,875
|
|
| G
|
Lmnb1
|
lamin B1
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of LMNB1 mRNA
|
CTD |
PMID:21795739 |
|
NCBI chr18:52,373,939...52,413,284
Ensembl chr18:52,373,757...52,413,283
|
|
| G
|
Lmo4
|
LIM domain only 4
|
increases expression
|
ISO
|
Progesterone results in increased expression of LMO4 mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr 2:235,924,574...235,941,609
Ensembl chr 2:235,924,403...235,941,275
|
|
| G
|
Lmod1
|
leiomodin 1
|
increases expression
|
ISO
|
Progesterone results in increased expression of LMOD1 mRNA
|
CTD |
PMID:20864642 |
|
NCBI chr13:46,754,048...46,796,186
Ensembl chr13:49,305,830...49,348,116
|
|
| G
|
Lox
|
lysyl oxidase
|
increases expression
|
ISO
|
Progesterone results in increased expression of LOX mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr18:48,162,889...48,175,640
Ensembl chr18:48,165,688...48,239,810
|
|
| G
|
Loxl2
|
lysyl oxidase-like 2
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of LOXL2 mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr15:51,091,547...51,182,843
Ensembl chr15:51,069,997...51,182,842
|
|
| G
|
Loxl4
|
lysyl oxidase-like 4
|
multiple interactions decreases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of LOXL4 mRNA; [Estradiol co-treated with Progesterone] results in increased expression of LOXL4 mRNA; Progesterone inhibits the reaction [Estradiol results in increased expression of LOXL4 mRNA] Progesterone results in decreased expression of LOXL4 mRNA
|
CTD |
PMID:20660070 PMID:20864642 PMID:21795739 |
|
NCBI chr 1:251,345,445...251,365,640
Ensembl chr 1:251,347,238...251,365,577
|
|
| G
|
Lpar1
|
lysophosphatidic acid receptor 1
|
increases expression
|
EXP
|
Progesterone results in increased expression of LPAR1 mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr 5:78,024,139...78,147,071
Ensembl chr 5:78,024,139...78,142,188
|
|
| G
|
Lpar3
|
lysophosphatidic acid receptor 3
|
increases expression multiple interactions
|
ISO
|
Progesterone results in increased expression of LPAR3 mRNA Estrogens inhibits the reaction [Progesterone results in increased expression of LPAR3 mRNA]; Mifepristone inhibits the reaction [Progesterone results in increased expression of LPAR3 mRNA]
|
CTD |
PMID:16815476 PMID:17404688 |
|
NCBI chr 2:237,785,371...237,854,199
Ensembl chr 2:237,787,766...237,854,197
|
|
| G
|
Lpcat3
|
lysophosphatidylcholine acyltransferase 3
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of LPCAT3 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 4:159,154,690...159,196,176
Ensembl chr 4:159,154,158...159,196,358
|
|
| G
|
Lpin1
|
lipin 1
|
increases expression
|
ISO
|
Progesterone results in increased expression of LPIN1 mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr 6:45,039,110...45,145,845
Ensembl chr 6:45,041,522...45,145,991
|
|
| G
|
Lpl
|
lipoprotein lipase
|
affects expression increases expression multiple interactions decreases expression
|
ISO EXP
|
Progesterone affects the expression of LPL mRNA Progesterone results in increased expression of LPL mRNA Progesterone inhibits the reaction [Dexamethasone results in increased activity of LPL protein] Progesterone results in decreased expression of LPL mRNA Progesterone inhibits the reaction [ESR1 protein promotes the reaction [Estradiol results in increased expression of LPL mRNA]]; Progesterone inhibits the reaction [ESR2 protein promotes the reaction [Estradiol results in increased expression of LPL mRNA]]; Progesterone inhibits the reaction [Estradiol results in increased expression of LPL mRNA]
|
CTD |
PMID:12906939 PMID:17251523 PMID:17974624 PMID:20726854 |
|
NCBI chr16:25,596,205...25,621,928
Ensembl chr16:25,596,211...25,622,107
|
|
| G
|
Lrig1
|
leucine-rich repeats and immunoglobulin-like domains 1
|
increases expression
|
ISO
|
Progesterone results in increased expression of LRIG1 mRNA
|
CTD |
PMID:20864642 |
|
NCBI chr 4:128,687,723...128,788,219
Ensembl chr 4:128,687,723...128,788,219
|
|
| G
|
Lrp2
|
LDL receptor related protein 2
|
affects expression
|
ISO
|
Progesterone affects the expression of LRP2 mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr 3:74,597,148...74,754,535
Ensembl chr 3:74,597,148...74,754,535
|
|
| G
|
Lrp4
|
LDL receptor related protein 4
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of LRP4 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 3:77,429,600...77,483,593
Ensembl chr 3:97,885,400...97,939,370
|
|
| G
|
Lrp8
|
LDL receptor related protein 8
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of LRP8 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 5:127,792,236...127,864,207
Ensembl chr 5:127,792,299...127,864,207
|
|
| G
|
Lrrc1
|
leucine rich repeat containing 1
|
increases expression decreases expression multiple interactions
|
ISO
|
Progesterone results in increased expression of LRRC1 mRNA Progesterone results in decreased expression of LRRC1 mRNA [Estradiol co-treated with Progesterone] results in increased expression of LRRC1 mRNA
|
CTD |
PMID:17404688 PMID:20660070 PMID:21540246 |
|
NCBI chr 8:78,239,897...78,407,347
Ensembl chr 8:87,119,975...87,286,853
|
|
| G
|
Lrrc17
|
leucine rich repeat containing 17
|
multiple interactions decreases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of LRRC17 mRNA Progesterone results in decreased expression of LRRC17 mRNA
|
CTD |
PMID:20660070 PMID:21795739 |
|
NCBI chr 4:14,393,632...14,424,048
Ensembl chr 4:14,393,640...14,424,048
|
|
| G
|
Lrrc32
|
leucine rich repeat containing 32
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of LRRC32 mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr 1:162,196,995...162,209,563
Ensembl chr 1:162,197,653...162,209,563
|
|
| G
|
Lrrc36
|
leucine rich repeat containing 36
|
increases expression
|
ISO
|
Progesterone results in increased expression of LRRC36 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr19:50,201,944...50,252,338
Ensembl chr19:50,201,987...50,252,338
|
|
| G
|
Lrrc8c
|
leucine rich repeat containing 8 VRAC subunit C
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of LRRC8C mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr14:4,528,721...4,621,259
Ensembl chr14:4,531,823...4,620,049
|
|
| G
|
Lrrc8d
|
leucine rich repeat containing 8 VRAC subunit D
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of LRRC8D mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr14:4,335,114...4,411,549
Ensembl chr14:4,332,130...4,445,639
|
|
| G
|
Lrrn1
|
leucine rich repeat neuronal 1
|
multiple interactions increases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of LRRN1 mRNA Progesterone results in increased expression of LRRN1 mRNA
|
CTD |
PMID:20660070 PMID:22238285 |
|
NCBI chr 4:142,032,805...142,072,320
Ensembl chr 4:142,032,041...142,074,760
|
|
| G
|
Lrrtm1
|
leucine rich repeat transmembrane neuronal 1
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of LRRTM1 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 4:111,246,213...111,295,638
Ensembl chr 4:111,235,054...111,276,818
|
|
| G
|
Lsr
|
lipolysis stimulated lipoprotein receptor
|
multiple interactions decreases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of LSR mRNA Progesterone results in decreased expression of LSR mRNA
|
CTD |
PMID:18556351 PMID:22238285 |
|
NCBI chr 1:95,313,830...95,329,471
Ensembl chr 1:95,313,033...95,329,354
|
|
| G
|
Lss
|
lanosterol synthase
|
increases expression multiple interactions
|
ISO
|
Progesterone results in increased expression of LSS mRNA [Estradiol co-treated with Progesterone] results in increased expression of LSS mRNA
|
CTD |
PMID:18070364 PMID:20660070 |
|
NCBI chr20:12,090,641...12,118,230
Ensembl chr20:12,073,543...12,118,253
|
|
| G
|
Lta
|
lymphotoxin alpha
|
increases expression
|
ISO
|
Progesterone results in increased expression of LTA mRNA
|
CTD |
PMID:21549006 |
|
NCBI chr20:3,622,291...3,625,852
Ensembl chr20:3,623,527...3,625,533
|
|
| G
|
Ltb
|
lymphotoxin beta
|
increases expression
|
ISO
|
Progesterone results in increased expression of LTB mRNA
|
CTD |
PMID:22615136 |
|
NCBI chr20:3,632,209...3,634,054
Ensembl chr20:3,632,210...3,634,054
|
|
| G
|
Ltbp1
|
latent transforming growth factor beta binding protein 1
|
multiple interactions increases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of LTBP1 mRNA; [Progesterone co-treated with Estradiol] results in increased expression of LTBP1 mRNA Progesterone results in increased expression of LTBP1 mRNA
|
CTD |
PMID:17404688 PMID:20660070 PMID:21795739 |
|
NCBI chr 6:20,029,629...20,425,339
Ensembl chr 6:25,781,638...26,454,036
|
|
| G
|
Ltf
|
lactotransferrin
|
affects expression
|
ISO
|
Progesterone affects the expression of LTF mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr 8:110,999,948...111,022,795
Ensembl chr 8:119,878,344...119,901,189
|
|
| G
|
Lum
|
lumican
|
increases expression
|
ISO
|
Progesterone results in increased expression of LUM mRNA
|
CTD |
PMID:21540246 |
|
NCBI chr 7:34,245,323...34,252,510
Ensembl chr 7:34,245,360...34,252,508
|
|
| G
|
Lxn
|
latexin
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of LXN mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr 2:154,037,604...154,043,473
Ensembl chr 2:154,037,292...154,043,488
|
|
| G
|
Ly6e
|
lymphocyte antigen 6 family member E
|
multiple interactions decreases expression
|
ISO
|
Mifepristone inhibits the reaction [Progesterone results in decreased expression of LY6E mRNA]
|
CTD |
PMID:27264040 PMID:31566189 |
|
NCBI chr 7:108,815,970...108,820,444
Ensembl chr 7:108,816,887...108,820,443
|
|
| G
|
Ly86
|
lymphocyte antigen 86
|
increases expression
|
ISO
|
Progesterone results in increased expression of LY86 mRNA
|
CTD |
PMID:21549006 |
|
NCBI chr17:27,621,313...27,705,336
Ensembl chr17:27,621,313...27,692,743
|
|
| G
|
Lypd1
|
Ly6/Plaur domain containing 1
|
multiple interactions increases expression
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of LYPD1 mRNA Progesterone results in increased expression of LYPD1 mRNA
|
CTD |
PMID:17404688 PMID:22238285 |
|
NCBI chr13:39,874,937...39,922,385
Ensembl chr13:39,879,096...39,922,338
|
|
| G
|
Lypd2
|
Ly6/Plaur domain containing 2
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of LYPD2 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 7:106,617,561...106,619,598
Ensembl chr 7:108,506,545...108,508,582
|
|
| G
|
Lyset
|
lysosomal enzyme trafficking factor
|
increases expression
|
ISO
|
Progesterone results in increased expression of LYSET mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr 6:121,884,577...121,886,319
Ensembl chr 6:127,649,450...127,652,661
|
|
| G
|
Lyz2
|
lysozyme 2
|
multiple interactions affects expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of LYZ mRNA Progesterone affects the expression of LYZ mRNA
|
CTD |
PMID:17251523 PMID:20660070 |
|
NCBI chr 7:54,792,715...54,798,060
Ensembl chr 7:54,792,716...54,798,011
|
|
| G
|
Lztfl1
|
leucine zipper transcription factor-like 1
|
multiple interactions increases expression
|
ISO
|
[Progesterone co-treated with TGFB1 protein] results in increased expression of LZTFL1 mRNA Progesterone results in increased expression of LZTFL1 mRNA
|
CTD |
PMID:21768398 |
|
NCBI chr 8:123,344,085...123,360,245
Ensembl chr 8:132,222,342...132,237,684
|
|
| G
|
Macc1
|
MET transcriptional regulator MACC1
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of MACC1 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 6:146,495,544...146,574,254
Ensembl chr 6:146,495,861...146,574,260
|
|
| G
|
Mad2l1
|
mitotic arrest deficient 2 like 1
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of MAD2L1 mRNA
|
CTD |
PMID:16966611 |
|
NCBI chr 4:97,236,419...97,247,603
Ensembl chr 4:97,236,503...97,243,222
|
|
| G
|
Maf
|
MAF bZIP transcription factor
|
increases expression multiple interactions
|
ISO
|
Progesterone results in increased expression of MAF mRNA [Estradiol co-treated with Progesterone] results in increased expression of MAF mRNA
|
CTD |
PMID:17404688 PMID:20660070 |
|
NCBI chr19:60,259,200...60,622,145
Ensembl chr19:60,269,541...60,621,378
|
|
| G
|
Mafb
|
MAF bZIP transcription factor B
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of MAFB mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 3:169,417,890...169,419,810
Ensembl chr 3:169,416,945...169,419,975
|
|
| G
|
Mal
|
mal, T-cell differentiation protein
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of MAL mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 3:135,317,664...135,341,423
Ensembl chr 3:135,317,664...135,341,423
|
|
| G
|
Mal2
|
mal, T-cell differentiation protein 2
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of MAL2 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 7:87,790,239...87,823,219
Ensembl chr 7:87,790,239...87,850,403
|
|
| G
|
Mamdc2
|
MAM domain containing 2
|
increases expression
|
ISO
|
Progesterone results in increased expression of MAMDC2 mRNA
|
CTD |
PMID:21795739 |
|
NCBI chr 1:220,863,959...221,016,493
Ensembl chr 1:230,290,499...230,442,711
|
|
| G
|
Man2b2
|
mannosidase, alpha, class 2B, member 2
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of MAN2B2 mRNA
|
CTD |
PMID:21540246 |
|
NCBI chr14:73,969,079...73,994,089
Ensembl chr14:78,193,725...78,227,724
|
|
| G
|
Manf
|
mesencephalic astrocyte-derived neurotrophic factor
|
affects expression increases expression
|
ISO
|
Progesterone affects the expression of MANF mRNA Progesterone results in increased expression of MANF mRNA
|
CTD |
PMID:17251523 PMID:18037150 |
|
NCBI chr 8:116,427,053...116,430,259
Ensembl chr 8:116,427,048...116,429,910
|
|
| G
|
Maoa
|
monoamine oxidase A
|
multiple interactions increases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of MAOA mRNA; [Progesterone co-treated with Estradiol] results in increased expression of MAOA mRNA Progesterone results in increased expression of MAOA mRNA
|
CTD |
PMID:17404688 PMID:20660070 PMID:20864642 |
|
NCBI chr X:8,615,239...8,681,372
Ensembl chr X:8,615,239...8,682,631
|
|
| G
|
Maob
|
monoamine oxidase B
|
multiple interactions increases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of MAOB mRNA; [Progesterone co-treated with Estradiol] results in increased expression of MAOB mRNA Progesterone results in increased expression of MAOB mRNA
|
CTD |
PMID:17404688 PMID:20660070 PMID:20864642 PMID:22238285 |
|
NCBI chr X:8,490,405...8,594,065
Ensembl chr X:8,490,344...8,594,375
|
|
| G
|
Map1b
|
microtubule-associated protein 1B
|
increases expression
|
EXP
|
Progesterone results in increased expression of MAP1B mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr 2:32,551,423...32,644,471
Ensembl chr 2:32,551,423...32,657,094
|
|
| G
|
Map2
|
microtubule-associated protein 2
|
increases expression decreases expression
|
ISO EXP
|
Progesterone results in increased expression of MAP2 mRNA Progesterone results in decreased expression of MAP2 mRNA Progesterone results in increased expression of MAP2 protein
|
CTD |
PMID:16054770 PMID:18037150 PMID:21795739 |
|
NCBI chr 9:75,173,038...75,431,606
Ensembl chr 9:75,288,262...75,428,459
|
|
| G
|
Map2k6
|
mitogen-activated protein kinase kinase 6
|
multiple interactions increases expression
|
ISO
|
[Progesterone co-treated with Estradiol] results in increased expression of MAP2K6 mRNA Progesterone results in increased expression of MAP2K6 mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr10:95,872,747...95,987,747
Ensembl chr10:95,872,546...95,987,721
|
|
| G
|
Map3k4
|
mitogen activated protein kinase kinase kinase 4
|
increases expression multiple interactions
|
ISO
|
Progesterone results in increased expression of MAP3K4 mRNA [Progesterone co-treated with Estradiol] results in increased expression of MAP3K4 mRNA
|
CTD |
PMID:18692832 PMID:20864642 |
|
NCBI chr 1:50,977,870...51,067,117
Ensembl chr 1:50,979,586...51,067,117
|
|
| G
|
Map3k7cl
|
MAP3K7 C-terminal like
|
multiple interactions decreases expression
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of MAP3K7CL mRNA Progesterone results in decreased expression of MAP3K7CL mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr11:40,276,839...40,321,848
Ensembl chr11:40,277,688...40,321,847
|
|
| G
|
Map3k8
|
mitogen-activated protein kinase kinase kinase 8
|
increases expression
|
ISO
|
Progesterone results in increased expression of MAP3K8 mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr17:58,078,175...58,098,455
Ensembl chr17:58,078,320...58,098,452
|
|
| G
|
Map4k4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of MAP4K4 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 9:49,696,573...49,822,353
Ensembl chr 9:49,696,700...49,822,353
|
|
| G
|
Map7
|
microtubule-associated protein 7
|
increases expression
|
ISO
|
Progesterone results in increased expression of MAP7 mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr 1:14,910,433...15,037,574
Ensembl chr 1:16,730,075...16,857,170
|
|
| G
|
Mapk1
|
mitogen activated protein kinase 1
|
multiple interactions increases phosphorylation decreases phosphorylation
|
ISO EXP
|
Mifepristone inhibits the reaction [Progesterone promotes the reaction [EGF protein results in increased phosphorylation of MAPK1 protein]]; Mifepristone inhibits the reaction [Progesterone promotes the reaction [Estradiol results in increased phosphorylation of MAPK1 protein]]; Progesterone promotes the reaction [EGF protein results in increased phosphorylation of MAPK1 protein]; Progesterone promotes the reaction [Estradiol results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [Progesterone promotes the reaction [EGF protein results in increased phosphorylation of MAPK1 protein]] Progesterone results in increased phosphorylation of MAPK1 protein [Progesterone co-treated with Halothane] results in increased phosphorylation of MAPK1 protein; U 0126 inhibits the reaction [[Progesterone co-treated with Halothane] results in increased phosphorylation of MAPK1 protein] [Estradiol co-treated with Progesterone co-treated with Methylnitrosourea] results in increased phosphorylation of MAPK1 protein; [Progesterone co-treated with Estrogens] results in increased phosphorylation of MAPK1 protein; Progesterone promotes the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK1 protein] Progesterone results in decreased phosphorylation of MAPK1 protein
|
CTD |
PMID:15358673 PMID:16175315 PMID:16284289 PMID:17492661 PMID:21258428 PMID:22157104 PMID:22345431 PMID:22465879 More...
|
|
NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825
|
|
| G
|
Mapk14
|
mitogen activated protein kinase 14
|
multiple interactions
|
EXP ISO
|
Progesterone promotes the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK14 protein] Progesterone inhibits the reaction [Ozone results in increased phosphorylation of MAPK14 protein]
|
CTD |
PMID:16284289 PMID:28279894 |
|
NCBI chr20:6,751,288...6,812,294
Ensembl chr20:6,751,357...6,812,294
|
|
| G
|
Mapk3
|
mitogen activated protein kinase 3
|
multiple interactions increases phosphorylation decreases phosphorylation
|
ISO EXP
|
Mifepristone inhibits the reaction [Progesterone promotes the reaction [EGF protein results in increased phosphorylation of MAPK3 protein]]; Mifepristone inhibits the reaction [Progesterone promotes the reaction [Estradiol results in increased phosphorylation of MAPK3 protein]]; Progesterone promotes the reaction [EGF protein results in increased phosphorylation of MAPK3 protein]; Progesterone promotes the reaction [Estradiol results in increased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [Progesterone promotes the reaction [EGF protein results in increased phosphorylation of MAPK3 protein]] Progesterone results in increased phosphorylation of MAPK3 protein [Progesterone co-treated with Halothane] results in increased phosphorylation of MAPK3 protein; U 0126 inhibits the reaction [[Progesterone co-treated with Halothane] results in increased phosphorylation of MAPK3 protein] [Estradiol co-treated with Progesterone co-treated with Methylnitrosourea] results in increased phosphorylation of MAPK3 protein; [Progesterone co-treated with Estrogens] results in increased phosphorylation of MAPK3 protein; Progesterone promotes the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK3 protein] Progesterone results in decreased phosphorylation of MAPK3 protein
|
CTD |
PMID:15358673 PMID:16175315 PMID:16284289 PMID:17492661 PMID:21258428 PMID:22157104 PMID:22345431 PMID:22465879 More...
|
|
NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411
|
|
| G
|
Mapk8
|
mitogen-activated protein kinase 8
|
multiple interactions
|
EXP
|
Progesterone promotes the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein]
|
CTD |
PMID:16284289 |
|
NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,645,198...8,728,427
|
|
| G
|
Mapk9
|
mitogen-activated protein kinase 9
|
increases expression
|
EXP
|
Progesterone results in increased expression of MAPK9 mRNA
|
CTD |
PMID:17170212 |
|
NCBI chr10:34,670,750...34,711,972
Ensembl chr10:34,670,756...34,712,228
|
|
| G
|
Mapt
|
microtubule-associated protein tau
|
increases phosphorylation decreases expression
|
EXP
|
Progesterone results in increased phosphorylation of MAPT protein Progesterone results in decreased expression of MAPT protein
|
CTD |
PMID:17443805 |
|
NCBI chr10:89,638,618...89,736,108
Ensembl chr10:89,638,599...89,736,108
|
|
| G
|
Marcks
|
myristoylated alanine rich protein kinase C substrate
|
multiple interactions decreases expression
|
ISO EXP
|
[Estradiol co-treated with Progesterone] results in decreased expression of MARCKS mRNA; [Progesterone co-treated with Estradiol] results in decreased expression of MARCKS mRNA Progesterone results in decreased expression of MARCKS mRNA
|
CTD |
PMID:17404688 PMID:20660070 PMID:20726854 |
|
NCBI chr20:42,240,185...42,245,882
Ensembl chr20:42,240,185...42,245,882
|
|
| G
|
Marcksl1
|
MARCKS-like 1
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of MARCKSL1 mRNA
|
CTD |
PMID:21795739 |
|
NCBI chr 5:141,851,491...141,853,814
Ensembl chr 5:147,134,514...147,138,417
|
|
| G
|
Mars1
|
methionyl-tRNA synthetase 1
|
increases expression
|
ISO
|
Progesterone results in increased expression of MARS1 mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr 7:65,006,456...65,023,880
Ensembl chr 7:64,998,544...65,023,753
|
|
| G
|
Mat2a
|
methionine adenosyltransferase 2A
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of MAT2A mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr 4:106,048,043...106,053,612
Ensembl chr 4:106,038,254...106,053,645
|
|
| G
|
Matcap2
|
microtubule associated tyrosine carboxypeptidase 2
|
increases expression
|
ISO
|
Progesterone results in increased expression of MATCAP2 mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr 8:20,921,637...20,971,076
Ensembl chr 8:29,196,927...29,247,058
|
|
| G
|
Matk
|
megakaryocyte-associated tyrosine kinase
|
increases expression
|
ISO
|
Progesterone results in increased expression of MATK mRNA; Progesterone results in increased expression of MATK protein
|
CTD |
PMID:17492661 |
|
NCBI chr 7:9,107,711...9,116,864
Ensembl chr 7:9,107,722...9,112,746
|
|
| G
|
Matn2
|
matrilin 2
|
multiple interactions increases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of MATN2 mRNA Progesterone results in increased expression of MATN2 mRNA
|
CTD |
PMID:20660070 PMID:21795739 |
|
NCBI chr 7:67,380,140...67,529,767
Ensembl chr 7:67,380,168...67,530,153
|
|
| G
|
Matn4
|
matrilin 4
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of MATN4 mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr 3:173,539,966...173,554,984
Ensembl chr 3:173,539,966...173,554,984
|
|
| G
|
Mboat1
|
membrane bound O-acyltransferase domain containing 1
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of MBOAT1 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr17:34,540,032...34,653,705
Ensembl chr17:34,540,041...34,653,698
|
|
| G
|
Mbp
|
myelin basic protein
|
multiple interactions
|
ISO EXP
|
[Progesterone co-treated with Estradiol] inhibits the reaction [Cuprizone results in decreased expression of MBP mRNA] Progesterone inhibits the reaction [Streptozocin results in decreased expression of MBP mRNA]
|
CTD |
PMID:19031445 PMID:20349157 |
|
NCBI chr18:78,130,652...78,241,174
Ensembl chr18:78,130,325...78,241,174
|
|
| G
|
Mc2r
|
melanocortin 2 receptor
|
multiple interactions increases secretion
|
EXP
|
MC2R protein promotes the reaction [PRL protein results in increased secretion of Progesterone]; PRL protein promotes the reaction [MC2R protein results in increased secretion of Progesterone]
|
CTD |
PMID:18609294 |
|
NCBI chr18:62,001,980...62,015,567
Ensembl chr18:64,277,360...64,291,881
|
|
| G
|
Mc4r
|
melanocortin 4 receptor
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of MC4R mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr18:60,419,832...60,421,719
|
|
| G
|
Mcm2
|
minichromosome maintenance complex component 2
|
multiple interactions decreases expression
|
ISO
|
[Progesterone co-treated with Estradiol] affects the localization of MCM2 protein; [Progesterone co-treated with Estradiol] results in decreased expression of MCM2 protein Progesterone results in decreased expression of MCM2 mRNA
|
CTD |
PMID:16966611 |
|
NCBI chr 4:122,903,679...122,918,205
Ensembl chr 4:122,903,682...122,918,094
|
|
| G
|
Mcm3
|
minichromosome maintenance complex component 3
|
multiple interactions decreases expression affects localization
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of MCM3 protein; Estradiol promotes the reaction [Progesterone affects the localization of MCM3 protein] Progesterone results in decreased expression of MCM3 mRNA
|
CTD |
PMID:16966611 |
|
NCBI chr 9:30,715,602...30,733,746
Ensembl chr 9:30,715,602...30,733,746
|
|
| G
|
Mcm4
|
minichromosome maintenance complex component 4
|
multiple interactions decreases expression
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of MCM4 protein Progesterone results in decreased expression of MCM4 mRNA
|
CTD |
PMID:16966611 |
|
NCBI chr11:98,762,599...98,776,300
Ensembl chr11:98,762,634...98,776,536
|
|
| G
|
Mcm5
|
minichromosome maintenance complex component 5
|
affects expression decreases expression
|
ISO
|
Progesterone affects the expression of MCM5 mRNA Progesterone results in decreased expression of MCM5 mRNA
|
CTD |
PMID:16966611 PMID:17251523 PMID:21795739 |
|
NCBI chr19:13,488,813...13,510,131
Ensembl chr19:13,488,813...13,517,758
|
|
| G
|
Mcm6
|
minichromosome maintenance complex component 6
|
multiple interactions decreases expression affects localization
|
ISO EXP
|
Estradiol inhibits the reaction [Progesterone affects the localization of MCM6 protein] Progesterone results in decreased expression of MCM6 mRNA
|
CTD |
PMID:16966611 PMID:20726854 |
|
NCBI chr13:42,379,161...42,404,352
Ensembl chr13:42,379,162...42,465,467
|
|
| G
|
Mcm7
|
minichromosome maintenance complex component 7
|
multiple interactions affects localization
|
ISO
|
Estradiol inhibits the reaction [Progesterone affects the localization of MCM7 protein]
|
CTD |
PMID:16966611 |
|
NCBI chr12:17,042,207...17,049,470
Ensembl chr12:22,155,921...22,163,771
|
|
| G
|
Mcub
|
mitochondrial calcium uniporter dominant negative subunit beta
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of MCUB mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 2:221,153,525...221,223,814
Ensembl chr 2:221,153,525...221,223,814
|
|
| G
|
Mdm1
|
Mdm1 nuclear protein
|
increases expression
|
ISO
|
Progesterone results in increased expression of MDM1 mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr 7:55,615,459...55,651,889
Ensembl chr 7:55,615,608...55,651,888
|
|
| G
|
Mdn1
|
midasin AAA ATPase 1
|
affects expression
|
ISO
|
Progesterone affects the expression of MDN1 mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr 5:47,055,435...47,190,426
Ensembl chr 5:51,851,809...51,982,688
|
|
| G
|
Meak7
|
MTOR associated protein, eak-7 homolog
|
increases expression
|
ISO
|
Progesterone results in increased expression of MEAK7 mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr19:47,813,899...47,836,830
Ensembl chr19:64,722,528...64,751,330
|
|
| G
|
Med27
|
mediator complex subunit 27
|
affects expression
|
ISO
|
Progesterone affects the expression of MED27 mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr 3:12,629,593...12,803,340
Ensembl chr 3:33,027,525...33,201,240
|
|
| G
|
Medag
|
mesenteric estrogen-dependent adipogenesis
|
increases expression
|
ISO
|
Progesterone results in increased expression of MEDAG mRNA
|
CTD |
PMID:21795739 |
|
NCBI chr12:5,613,191...5,634,583
Ensembl chr12:10,649,526...10,692,756
|
|
| G
|
Megf10
|
multiple EGF-like domains 10
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of MEGF10 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr18:50,605,231...50,755,441
Ensembl chr18:52,847,781...52,950,675
|
|
| G
|
Meig1
|
meiosis/spermiogenesis associated 1
|
increases expression
|
ISO
|
Progesterone results in increased expression of MEIG1 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr17:79,718,630...79,737,604
Ensembl chr17:79,723,811...79,737,533
|
|
| G
|
Meltf
|
melanotransferrin
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of MELTF mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr11:68,884,446...68,906,300
Ensembl chr11:82,389,420...82,411,270
|
|
| G
|
Metap2
|
methionyl aminopeptidase 2
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of METAP2 mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr 7:30,299,433...30,327,477
Ensembl chr 7:30,299,433...30,327,521
|
|
| G
|
Mex3a
|
mex-3 RNA binding family member A
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of MEX3A mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 2:173,990,098...173,999,567
Ensembl chr 2:176,287,900...176,297,369
|
|
| G
|
Mfap2
|
microfibril associated protein 2
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of MFAP2 mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr 5:158,595,121...158,603,283
Ensembl chr 5:158,597,512...158,610,656
|
|
| G
|
Mfap4
|
microfibril associated protein 4
|
increases expression
|
ISO
|
Progesterone results in increased expression of MFAP4 mRNA
|
CTD |
PMID:21540246 |
|
NCBI chr10:46,666,552...46,669,613
Ensembl chr10:46,655,722...46,669,740
|
|
| G
|
Mfap5
|
microfibril associated protein 5
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of MFAP5 mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr 4:155,727,925...155,750,458
Ensembl chr 4:157,395,597...157,422,448
|
|
| G
|
Mfng
|
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
|
increases expression
|
ISO
|
Progesterone results in increased expression of MFNG mRNA
|
CTD |
PMID:21540246 |
|
NCBI chr 7:112,191,288...112,209,129
Ensembl chr 7:112,161,071...112,209,129
|
|
| G
|
Mgat3
|
beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of MGAT3 mRNA
|
CTD |
PMID:19693291 |
|
NCBI chr 7:113,614,011...113,640,201
Ensembl chr 7:113,598,059...113,643,481
|
|
| G
|
Mgp
|
matrix Gla protein
|
decreases expression increases expression
|
ISO
|
Progesterone results in decreased expression of MGP mRNA Progesterone results in increased expression of MGP mRNA
|
CTD |
PMID:18070364 PMID:21795739 |
|
NCBI chr 4:169,766,290...169,769,612
Ensembl chr 4:171,497,471...171,500,859
|
|
| G
|
Mgst1
|
microsomal glutathione S-transferase 1
|
multiple interactions increases expression
|
ISO EXP
|
[Estradiol co-treated with Progesterone] results in increased expression of MGST1 mRNA Progesterone results in increased expression of MGST1 mRNA
|
CTD |
PMID:20660070 PMID:20726854 |
|
NCBI chr 4:172,760,930...172,776,157
Ensembl chr 4:172,760,886...172,776,875
|
|
| G
|
Mia
|
MIA SH3 domain containing
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of MIA mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 1:82,473,677...82,476,378
Ensembl chr 1:91,601,327...91,603,019
|
|
| G
|
Mical2
|
microtubule associated monooxygenase, calponin and LIM domain containing 2
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of MICAL2 mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr 1:175,780,441...175,965,157
Ensembl chr 1:175,825,596...175,905,155
|
|
| G
|
Mid1
|
midline 1
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of MID1 mRNA
|
CTD |
PMID:21795739 |
|
NCBI chr X:24,116,674...24,491,205
Ensembl chr X:27,681,867...27,906,105
|
|
| G
|
Mir100
|
microRNA 100
|
decreases expression multiple interactions
|
ISO
|
Progesterone results in decreased expression of MIR100 mRNA [Estradiol co-treated with Progesterone] results in decreased expression of MIR100 mRNA
|
CTD |
PMID:22950660 PMID:30328349 |
|
NCBI chr 8:41,901,225...41,901,304
Ensembl chr 8:50,798,295...50,798,374
|
|
| G
|
Mir106b
|
microRNA 106b
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of MIR106B mRNA
|
CTD |
PMID:22950660 |
|
NCBI chr12:17,043,344...17,043,425
|
|
| G
|
Mir10a
|
microRNA 10a
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of MIR10A mRNA
|
CTD |
PMID:30328349 |
|
NCBI chr10:81,283,171...81,283,280
Ensembl chr10:81,779,709...81,779,818
|
|
| G
|
Mir122
|
microRNA 122
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of MIR122 mRNA
|
CTD |
PMID:22950660 |
|
NCBI chr18:58,758,703...58,758,787
|
|
| G
|
Mir128-2
|
microRNA 128-2
|
increases expression
|
ISO
|
Progesterone results in increased expression of MIR128-2 mRNA
|
CTD |
PMID:22950660 |
|
NCBI chr 8:112,085,467...112,085,550
|
|
| G
|
Mir134
|
microRNA 134
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of MIR134 mRNA
|
CTD |
PMID:22950660 |
|
NCBI chr 6:128,748,908...128,748,980
|
|
| G
|
Mir135b
|
microRNA 135b
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of MIR135B mRNA
|
CTD |
PMID:22950660 |
|
NCBI chr13:43,638,857...43,638,953
Ensembl chr13:46,191,018...46,191,114
|
|
| G
|
Mir142
|
microRNA 142
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of MIR142 mRNA
|
CTD |
PMID:22950660 |
|
NCBI chr10:72,557,864...72,557,950
Ensembl chr10:73,055,097...73,055,207
|
|
| G
|
Mir144
|
microRNA 144
|
decreases expression multiple interactions
|
ISO
|
Progesterone results in decreased expression of MIR144 mRNA [Progesterone co-treated with Estradiol] results in increased expression of MIR144 mRNA
|
CTD |
PMID:22950660 |
|
NCBI chr10:63,459,397...63,459,479
Ensembl chr10:63,459,397...63,459,479
|
|
| G
|
Mir145
|
microRNA 145
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of MIR145 mRNA
|
CTD |
PMID:30328349 |
|
NCBI chr18:57,369,983...57,370,070
|
|
| G
|
Mir146a
|
microRNA 146a
|
decreases expression multiple interactions
|
ISO
|
Progesterone results in decreased expression of MIR146A mRNA Progesterone promotes the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of MIR146 mRNA]
|
CTD |
PMID:22546503 PMID:22950660 |
|
NCBI chr10:27,848,516...27,848,610
|
|
| G
|
Mir146b
|
microRNA 146b
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of MIR146B mRNA
|
CTD |
PMID:22950660 |
|
NCBI chr 1:245,203,438...245,203,525
Ensembl chr 1:255,144,860...255,144,947
|
|
| G
|
Mir148a
|
microRNA 148a
|
decreases expression multiple interactions
|
ISO
|
Progesterone results in decreased expression of MIR148A mRNA [Estradiol co-treated with Progesterone] results in decreased expression of MIR148A mRNA
|
CTD |
PMID:30328349 |
|
NCBI chr 4:80,333,762...80,333,858
|
|
| G
|
Mir148b
|
microRNA 148b
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of MIR148B mRNA
|
CTD |
PMID:30328349 |
|
NCBI chr 7:134,421,398...134,421,494
Ensembl chr 7:136,299,870...136,299,966
|
|
| G
|
Mir151
|
microRNA 151
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of MIR151A mRNA
|
CTD |
PMID:30328349 |
|
NCBI chr 7:105,172,377...105,172,473
|
|
| G
|
Mir151b
|
microRNA 151b
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of MIR151B mRNA
|
CTD |
PMID:30328349 |
|
NCBI chr 7:105,172,377...105,172,496
Ensembl chr 7:107,061,380...107,061,499
|
|
| G
|
Mir155
|
microRNA 155
|
multiple interactions increases expression
|
ISO
|
[Progesterone co-treated with Estradiol] results in increased expression of MIR155 mRNA MIR155 mRNA inhibits the reaction [Progesterone inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of IL6 protein]]; MIR155 mRNA inhibits the reaction [Progesterone inhibits the reaction [Poly I-C results in increased expression of MIR155 mRNA]]; Progesterone inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of MIR155 mRNA]; Progesterone inhibits the reaction [Poly I-C results in increased expression of MIR155 mRNA] Progesterone results in increased expression of MIR155 mRNA
|
CTD |
PMID:22546503 PMID:22950660 |
|
NCBI chr11:37,261,114...37,261,178
Ensembl chr11:37,261,114...37,261,178
|
|
| G
|
Mir155hg
|
Mir155 host gene
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of BIC mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr11:23,773,468...23,775,697
|
|
| G
|
Mir15b
|
microRNA 15b
|
decreases expression increases expression
|
ISO
|
Progesterone results in decreased expression of MIR15B mRNA Progesterone results in increased expression of MIR15B mRNA
|
CTD |
PMID:22950660 PMID:30328349 |
|
NCBI chr 2:153,245,200...153,245,297
Ensembl chr 2:155,555,178...155,555,275
|
|
| G
|
Mir181c
|
microRNA 181c
|
increases expression
|
ISO
|
Progesterone results in increased expression of MIR181C mRNA
|
CTD |
PMID:22950660 |
|
NCBI chr19:23,983,523...23,983,628
Ensembl chr19:40,888,291...40,888,396
|
|
| G
|
Mir181d
|
microRNA 181d
|
increases expression multiple interactions
|
ISO
|
Progesterone results in increased expression of MIR181D mRNA [Estradiol co-treated with Progesterone] results in decreased expression of MIR181D mRNA
|
CTD |
PMID:22950660 PMID:30328349 |
|
NCBI chr19:23,983,706...23,983,788
Ensembl chr19:40,888,474...40,888,556
|
|
| G
|
Mir186
|
microRNA 186
|
increases expression decreases expression
|
ISO
|
Progesterone results in increased expression of MIR186 mRNA Progesterone results in decreased expression of MIR186 mRNA
|
CTD |
PMID:22950660 PMID:30328349 |
|
NCBI chr 2:246,582,806...246,582,891
Ensembl chr 2:249,241,650...249,241,735
|
|
| G
|
Mir191
|
microRNA 191
|
increases expression
|
ISO
|
Progesterone results in increased expression of MIR191 mRNA
|
CTD |
PMID:22950660 |
|
NCBI chr 8:109,264,098...109,264,188
|
|
| G
|
Mir195
|
microRNA 195
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of MIR195 mRNA
|
CTD |
PMID:22950660 |
|
NCBI chr10:54,951,838...54,951,924
Ensembl chr10:55,450,495...55,450,581
|
|
| G
|
Mir196b
|
microRNA 196b
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of MIR196B mRNA
|
CTD |
PMID:22950660 |
|
NCBI chr 4:81,330,487...81,330,571
|
|
| G
|
Mir202
|
microRNA 202
|
increases expression
|
ISO
|
Progesterone results in increased expression of MIR202 mRNA
|
CTD |
PMID:22950660 |
|
NCBI chr 1:194,754,730...194,754,801
|
|
| G
|
Mir204
|
microRNA 204
|
increases expression
|
ISO
|
Progesterone results in increased expression of MIR204 mRNA
|
CTD |
PMID:22950660 |
|
NCBI chr 1:229,743,461...229,743,570
Ensembl chr 1:229,743,461...229,743,570
|
|
| G
|
Mir206
|
microRNA 206
|
increases expression
|
ISO
|
Progesterone results in increased expression of MIR206 mRNA
|
CTD |
PMID:22950660 |
|
NCBI chr 9:23,094,249...23,094,332
Ensembl chr 9:30,590,697...30,590,780
|
|
| G
|
Mir20b
|
microRNA 20b
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of MIR20B mRNA
|
CTD |
PMID:22950660 PMID:30328349 |
|
NCBI chr X:132,422,211...132,422,282
|
|
| G
|
Mir21
|
microRNA 21
|
increases expression
|
ISO
|
Progesterone results in increased expression of MIR21 mRNA
|
CTD |
PMID:30328349 |
|
NCBI chr10:71,902,600...71,902,691
|
|
| G
|
Mir22
|
microRNA 22
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of MIR22 mRNA
|
CTD |
PMID:30328349 |
|
NCBI chr10:60,805,331...60,805,425
Ensembl chr10:60,805,331...60,805,425
|
|
| G
|
Mir221
|
microRNA 221
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of MIR221 mRNA
|
CTD |
PMID:22950660 |
|
NCBI chr X:3,429,465...3,429,573
Ensembl chr X:6,023,182...6,023,290
|
|
| G
|
Mir23a
|
microRNA 23a
|
increases expression
|
ISO
|
Progesterone results in increased expression of MIR23A mRNA
|
CTD |
PMID:30328349 |
|
NCBI chr19:23,954,997...23,955,071
|
|
| G
|
Mir23b
|
microRNA 23b
|
increases expression
|
ISO
|
Progesterone results in increased expression of MIR23B mRNA
|
CTD |
PMID:30328349 |
|
NCBI chr17:1,813,667...1,813,763
|
|
| G
|
Mir25
|
microRNA 25
|
increases expression
|
ISO
|
Progesterone results in increased expression of MIR25 mRNA
|
CTD |
PMID:22950660 |
|
NCBI chr12:17,042,932...17,043,015
|
|
| G
|
Mir26b
|
microRNA 26b
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in increased expression of MIR26B mRNA
|
CTD |
PMID:22950660 |
|
NCBI chr 9:75,976,596...75,976,680
Ensembl chr 9:83,425,709...83,425,793
|
|
| G
|
Mir27a
|
microRNA 27a
|
multiple interactions decreases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of MIR27A mRNA Progesterone results in decreased expression of MIR27A mRNA
|
CTD |
PMID:30328349 |
|
NCBI chr19:23,954,831...23,954,917
|
|
| G
|
Mir27b
|
microRNA 27b
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of MIR27B mRNA
|
CTD |
PMID:30328349 |
|
NCBI chr17:1,819,147...1,819,243
|
|
| G
|
Mir296
|
microRNA 296
|
increases expression
|
ISO
|
Progesterone results in increased expression of MIR296 mRNA
|
CTD |
PMID:22950660 |
|
NCBI chr 3:163,051,838...163,051,915
|
|
| G
|
Mir299a
|
microRNA 299B
|
increases expression
|
ISO
|
Progesterone results in increased expression of MIR299 mRNA
|
CTD |
PMID:22950660 |
|
NCBI chr 6:128,723,635...128,723,752
|
|
| G
|
Mir29a
|
microRNA 29a
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of MIR29A mRNA
|
CTD |
PMID:30328349 |
|
NCBI chr 4:59,650,608...59,650,695
|
|
| G
|
Mir30d
|
microRNA 30d
|
increases expression
|
ISO
|
Progesterone results in increased expression of MIR30D mRNA
|
CTD |
PMID:22950660 |
|
NCBI chr 7:100,136,391...100,136,472
|
|
| G
|
Mir30e
|
microRNA 30e
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of MIR30E mRNA
|
CTD |
PMID:22950660 |
|
NCBI chr 5:134,352,232...134,352,323
Ensembl chr 5:139,637,450...139,637,541
|
|
| G
|
Mir320a
|
microRNA 320a
|
increases expression
|
ISO
|
Progesterone results in increased expression of MIR320A mRNA
|
CTD |
PMID:30328349 |
|
NCBI chr15:45,516,392...45,516,473
Ensembl chr15:51,926,088...51,926,169
|
|
| G
|
Mir322
|
microRNA 322
|
multiple interactions decreases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of MIR424 mRNA Progesterone results in decreased expression of MIR424 mRNA
|
CTD |
PMID:30328349 |
|
NCBI chr X:132,806,594...132,806,688
|
|
| G
|
Mir328
|
microRNA 328
|
increases expression
|
ISO
|
Progesterone results in increased expression of MIR328 mRNA
|
CTD |
PMID:22950660 |
|
NCBI chr19:33,184,766...33,184,849
|
|
| G
|
Mir337
|
microRNA 337
|
increases expression
|
ISO
|
Progesterone results in increased expression of MIR337 mRNA
|
CTD |
PMID:22950660 |
|
NCBI chr 6:128,538,903...128,538,999
Ensembl chr 6:134,321,141...134,321,237
|
|
| G
|
Mir345
|
microRNA 345
|
increases expression
|
ISO
|
Progesterone results in increased expression of MIR345 mRNA
|
CTD |
PMID:22950660 |
|
NCBI chr 6:127,754,027...127,754,122
Ensembl chr 6:133,518,403...133,518,498
|
|
| G
|
Mir346
|
microRNA 346
|
multiple interactions increases expression
|
ISO
|
[Progesterone co-treated with Estradiol] results in increased expression of MIR346 mRNA Progesterone results in increased expression of MIR346 mRNA
|
CTD |
PMID:22950660 |
|
NCBI chr16:10,218,118...10,218,215
Ensembl chr16:10,224,300...10,224,397
|
|
| G
|
Mir34b
|
microRNA 34b
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of MIR34B mRNA
|
CTD |
PMID:22950660 |
|
NCBI chr 8:60,306,609...60,306,692
|
|
| G
|
Mir361
|
microRNA 361
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of MIR361 mRNA
|
CTD |
PMID:30328349 |
|
NCBI chr X:78,246,206...78,246,275
|
|
| G
|
Mir363
|
microRNA 363
|
increases expression
|
ISO
|
Progesterone results in increased expression of MIR363 mRNA
|
CTD |
PMID:22950660 |
|
NCBI chr X:132,421,791...132,421,877
|
|
| G
|
Mir411
|
microRNA 411
|
decreases expression multiple interactions
|
ISO
|
Progesterone results in decreased expression of MIR411 mRNA [Progesterone co-treated with Estradiol] results in decreased expression of MIR411 mRNA
|
CTD |
PMID:22950660 |
|
NCBI chr 6:128,723,189...128,723,264
Ensembl chr 6:134,544,589...134,544,684
|
|
| G
|
Mir412
|
microRNA 412
|
increases expression
|
ISO
|
Progesterone results in increased expression of MIR412 mRNA
|
CTD |
PMID:22950660 |
|
NCBI chr 6:128,757,932...128,758,001
Ensembl chr 6:134,579,331...134,579,410
|
|
| G
|
Mir423
|
microRNA 423
|
multiple interactions increases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of MIR423 mRNA Progesterone results in increased expression of MIR423 mRNA
|
CTD |
PMID:30328349 |
|
NCBI chr10:61,914,142...61,914,220
|
|
| G
|
Mir425
|
microRNA 425
|
increases expression decreases expression
|
ISO
|
Progesterone results in increased expression of MIR425 mRNA Progesterone results in decreased expression of MIR425 mRNA
|
CTD |
PMID:22950660 PMID:30328349 |
|
NCBI chr 8:118,143,084...118,143,166
Ensembl chr 8:118,143,084...118,143,166
|
|
| G
|
Mir448
|
microRNA 448
|
increases expression
|
ISO
|
Progesterone results in increased expression of MIR448 mRNA
|
CTD |
PMID:22950660 |
|
NCBI chr X:115,641,955...115,642,066
Ensembl chr X:115,641,955...115,642,066
|
|
| G
|
Mir449a
|
microRNA 449a
|
multiple interactions decreases expression
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of MIR449A mRNA Progesterone results in decreased expression of MIR449A mRNA
|
CTD |
PMID:22950660 |
|
NCBI chr 2:44,670,714...44,670,804
Ensembl chr 2:46,403,910...46,404,000
|
|
| G
|
Mir455
|
microRNA 455
|
multiple interactions decreases expression
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of MIR455 mRNA Progesterone results in decreased expression of MIR455 mRNA
|
CTD |
PMID:22950660 |
|
NCBI chr 5:76,689,313...76,689,390
Ensembl chr 5:81,704,834...81,704,911
|
|
| G
|
Mir486
|
microRNA 486
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of MIR486-1 mRNA
|
CTD |
PMID:22950660 |
|
|
|
| G
|
Mir500
|
microRNA 500
|
multiple interactions increases expression
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of MIR502 mRNA Progesterone results in increased expression of MIR502 mRNA
|
CTD |
PMID:22950660 |
|
NCBI chr X:15,258,778...15,258,857
Ensembl chr X:17,930,637...17,930,728
|
|
| G
|
Mir503
|
microRNA 503
|
multiple interactions increases expression
|
ISO
|
[Progesterone co-treated with Estradiol] results in increased expression of MIR503 mRNA Progesterone results in increased expression of MIR503 mRNA
|
CTD |
PMID:22950660 |
|
NCBI chr X:132,806,303...132,806,373
|
|
| G
|
Mir504
|
microRNA 504
|
increases expression
|
ISO
|
Progesterone results in increased expression of MIR504 mRNA
|
CTD |
PMID:22950660 |
|
NCBI chr X:137,318,540...137,318,616
|
|
| G
|
Mir542
|
microRNA 542
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of MIR542 mRNA
|
CTD |
PMID:22950660 |
|
NCBI chr X:132,802,623...132,802,701
|
|
| G
|
Mir592
|
microRNA 592
|
increases expression
|
ISO
|
Progesterone results in increased expression of MIR592 mRNA
|
CTD |
PMID:22950660 |
|
NCBI chr 4:56,505,280...56,505,375
|
|
| G
|
Mir632
|
microRNA 632
|
increases expression
|
ISO
|
Progesterone results in increased expression of MIR632 mRNA
|
CTD |
PMID:22950660 |
|
NCBI chr10:65,385,757...65,385,834
Ensembl chr10:65,883,580...65,883,657
|
|
| G
|
Mir671
|
microRNA 671
|
increases expression
|
ISO
|
Progesterone results in increased expression of MIR671 mRNA
|
CTD |
PMID:22950660 |
|
NCBI chr 4:10,580,747...10,580,827
|
|
| G
|
Mir675
|
microRNA 675
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of MIR675 mRNA
|
CTD |
PMID:22950660 |
|
NCBI chr 1:207,161,752...207,161,835
|
|
| G
|
Mir876
|
microRNA 876
|
increases expression multiple interactions
|
ISO
|
Progesterone results in increased expression of MIR876 mRNA [Progesterone co-treated with Estradiol] results in increased expression of MIR876 mRNA
|
CTD |
PMID:22950660 |
|
NCBI chr 5:51,337,191...51,337,269
|
|
| G
|
Mir92b
|
microRNA 92b
|
increases expression
|
ISO
|
Progesterone results in increased expression of MIR92B mRNA
|
CTD |
PMID:22950660 |
|
NCBI chr 2:174,633,890...174,633,972
|
|
| G
|
Mir93
|
microRNA 93
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of MIR93 mRNA
|
CTD |
PMID:22950660 |
|
NCBI chr12:22,156,844...22,156,930
|
|
| G
|
Mir99a
|
microRNA 99a
|
multiple interactions decreases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of MIR99A mRNA; [Progesterone co-treated with Estradiol] results in decreased expression of MIR99A mRNA Progesterone results in decreased expression of MIR99A mRNA
|
CTD |
PMID:22950660 PMID:30328349 |
|
NCBI chr11:16,200,443...16,200,523
Ensembl chr11:29,687,392...29,687,472
|
|
| G
|
Mir99b
|
microRNA 99b
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of MIR99B mRNA
|
CTD |
PMID:30328349 |
|
NCBI chr 1:58,677,015...58,677,084
Ensembl chr 1:67,350,060...67,350,139
|
|
| G
|
Mirlet7b
|
microRNA let-7b
|
increases expression
|
ISO
|
Progesterone results in increased expression of MIRLET7B mRNA
|
CTD |
PMID:30328349 |
|
NCBI chr 7:116,804,186...116,804,270
Ensembl chr 7:118,684,038...118,684,122
|
|
| G
|
Mirlet7c1
|
microRNA let-7c-1
|
increases expression
|
ISO
|
Progesterone results in increased expression of MIRLET7C mRNA
|
CTD |
PMID:30328349 |
|
NCBI chr11:16,201,163...16,201,256
Ensembl chr11:29,688,107...29,688,214
|
|
| G
|
Mirlet7d
|
microRNA let-7d
|
increases expression
|
ISO
|
Progesterone results in increased expression of MIRLET7D mRNA
|
CTD |
PMID:30328349 |
|
NCBI chr17:16,115,893...16,115,990
Ensembl chr17:16,322,260...16,322,357
|
|
| G
|
Mirlet7i
|
microRNA let-7i
|
increases expression
|
ISO
|
Progesterone results in increased expression of MIRLET7I mRNA
|
CTD |
PMID:30328349 |
|
NCBI chr 7:58,642,485...58,642,569
|
|
| G
|
Mitf
|
melanocyte inducing transcription factor
|
increases expression
|
ISO
|
Progesterone results in increased expression of MITF mRNA
|
CTD |
PMID:20864642 |
|
NCBI chr 4:131,965,676...132,177,790
Ensembl chr 4:131,965,714...132,177,790
|
|
| G
|
Mki67
|
marker of proliferation Ki-67
|
increases expression multiple interactions affects expression decreases expression
|
ISO EXP
|
Progesterone results in increased expression of MKI67 mRNA Copper promotes the reaction [[Progesterone co-treated with Estrogens] results in decreased expression of MKI67 protein]; Lead inhibits the reaction [[Progesterone co-treated with Estrogens] results in decreased expression of MKI67 protein] [Estrogens co-treated with Progesterone] results in increased expression of MKI67 protein Progesterone affects the expression of MKI67 mRNA; Progesterone affects the expression of MKI67 protein Progesterone results in decreased expression of MKI67 mRNA Lithium Chloride inhibits the reaction [Progesterone inhibits the reaction [Estradiol results in increased expression of MKI67 protein]]; Progesterone inhibits the reaction [Estradiol results in increased expression of MKI67 protein]
|
CTD |
PMID:15845746 PMID:16800253 PMID:16888808 PMID:16966611 PMID:17251523 PMID:22238285 PMID:32004626 More...
|
|
NCBI chr 1:199,926,150...199,952,847
Ensembl chr 1:199,926,150...199,952,593
|
|
| G
|
Mknk2
|
MAPK interacting serine/threonine kinase 2
|
increases expression
|
ISO
|
Progesterone results in increased expression of MKNK2 mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr 7:9,039,771...9,050,832
Ensembl chr 7:9,690,421...9,701,529
|
|
| G
|
Mllt11
|
MLLT11, transcription factor 7 cofactor
|
increases expression
|
ISO
|
Progesterone results in increased expression of MLLT11 mRNA
|
CTD |
PMID:21540246 |
|
NCBI chr 2:182,795,790...182,804,960
Ensembl chr 2:185,484,793...185,493,961
|
|
| G
|
Mlph
|
melanophilin
|
increases expression
|
ISO
|
Progesterone results in increased expression of MLPH mRNA
|
CTD |
PMID:21540246 |
|
NCBI chr 9:98,955,036...98,990,566
Ensembl chr 9:98,955,141...98,990,556
|
|
| G
|
Mmd
|
monocyte to macrophage differentiation-associated
|
increases expression
|
ISO
|
Progesterone results in increased expression of MMD mRNA
|
CTD |
PMID:20864642 |
|
NCBI chr10:75,570,366...75,598,610
Ensembl chr10:75,570,397...75,598,609
|
|
| G
|
Mme
|
membrane metallo-endopeptidase
|
decreases expression increases expression affects expression
|
ISO
|
Progesterone results in decreased expression of MME mRNA Progesterone results in increased expression of MME mRNA Progesterone affects the expression of MME mRNA
|
CTD |
PMID:17251523 PMID:18070364 PMID:21795739 |
|
NCBI chr 2:149,806,826...149,957,381
Ensembl chr 2:149,872,291...149,953,463
|
|
| G
|
Mmp1
|
matrix metallopeptidase 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of MMP1 mRNA; [Progesterone co-treated with Estradiol] results in decreased expression of MMP1 mRNA; Progesterone inhibits the reaction [IL1B protein results in increased expression of MMP1 protein modified form]
|
CTD |
PMID:17404688 PMID:20660070 PMID:22219637 |
|
NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:12,943,453...12,963,964
|
|
| G
|
Mmp10
|
matrix metallopeptidase 10
|
multiple interactions increases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of MMP10 mRNA; [Progesterone co-treated with Estradiol] results in increased expression of MMP10 mRNA Progesterone results in increased expression of MMP10 mRNA
|
CTD |
PMID:20226447 PMID:20660070 |
|
NCBI chr 8:12,974,707...12,982,613
Ensembl chr 8:12,974,707...12,982,613
|
|
| G
|
Mmp11
|
matrix metallopeptidase 11
|
multiple interactions decreases expression affects expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of MMP11 mRNA; [Progesterone co-treated with Estradiol] results in decreased expression of MMP11 mRNA; [Progesterone co-treated with Estradiol] results in increased expression of MMP11 mRNA; Progesterone inhibits the reaction [Estradiol results in increased expression of MMP11 mRNA] Progesterone results in decreased expression of MMP11 mRNA Progesterone affects the expression of MMP11 mRNA
|
CTD |
PMID:17251523 PMID:17404688 PMID:20226447 PMID:20660070 PMID:20864642 PMID:21795739 More...
|
|
NCBI chr20:12,730,284...12,739,067
Ensembl chr20:12,730,277...12,739,290
|
|
| G
|
Mmp12
|
matrix metallopeptidase 12
|
affects expression
|
ISO
|
Progesterone affects the expression of MMP12 mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr 8:4,581,785...4,591,687
Ensembl chr 8:12,866,641...12,884,478
|
|
| G
|
Mmp13
|
matrix metallopeptidase 13
|
multiple interactions
|
ISO
|
Progesterone inhibits the reaction [Estradiol results in increased expression of MMP13 mRNA]
|
CTD |
PMID:19416213 |
|
NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:12,782,813...12,793,105
|
|
| G
|
Mmp14
|
matrix metallopeptidase 14
|
multiple interactions increases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of MMP14 protein; [Estrogens co-treated with Progesterone co-treated with IL1B protein] results in increased expression of MMP14 mRNA; [Progesterone co-treated with Estradiol] results in decreased expression of MMP14 mRNA; Estradiol inhibits the reaction [Progesterone results in increased expression of MMP14 mRNA]
|
CTD |
PMID:17404688 PMID:18570937 PMID:18692832 PMID:18829229 PMID:26604029 |
|
NCBI chr15:31,857,824...31,867,049
Ensembl chr15:31,857,546...31,869,893
|
|
| G
|
Mmp16
|
matrix metallopeptidase 16
|
multiple interactions decreases expression
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of MMP16 mRNA Progesterone results in decreased expression of MMP16 mRNA
|
CTD |
PMID:20226447 |
|
NCBI chr 5:36,109,265...36,353,252
Ensembl chr 5:36,109,265...36,353,252
|
|
| G
|
Mmp2
|
matrix metallopeptidase 2
|
decreases expression multiple interactions
|
ISO
|
Progesterone results in decreased expression of MMP2 mRNA [Estradiol co-treated with Progesterone] results in increased expression of and results in increased activity of MMP2 protein; Progesterone inhibits the reaction [IL1B protein results in increased expression of MMP2 protein modified form]
|
CTD |
PMID:18070364 PMID:18829229 PMID:22219637 |
|
NCBI chr19:30,327,643...30,355,856
Ensembl chr19:30,327,643...30,355,856
|
|
| G
|
Mmp27
|
matrix metallopeptidase 27
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of MMP27 mRNA; [Progesterone co-treated with Estradiol] results in decreased expression of MMP27 mRNA
|
CTD |
PMID:17404688 PMID:20660070 |
|
NCBI chr 8:13,030,752...13,040,671
Ensembl chr 8:13,030,746...13,040,671
|
|
| G
|
Mmp3
|
matrix metallopeptidase 3
|
multiple interactions decreases expression decreases secretion
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased secretion of MMP3 protein; [Estrogens co-treated with Progesterone co-treated with IL1B protein] results in increased expression of MMP3 mRNA; [Progesterone co-treated with Estradiol] results in decreased expression of MMP3 mRNA; Progesterone inhibits the reaction [IL1B protein results in increased expression of MMP3 protein modified form]; Tetrachlorodibenzodioxin inhibits the reaction [Progesterone results in decreased secretion of MMP3 protein]; Triclosan inhibits the reaction [Progesterone results in decreased expression of MMP3 mRNA] Mifepristone inhibits the reaction [Progesterone results in decreased expression of MMP3 mRNA]; Progesterone inhibits the reaction [Estradiol results in increased expression of MMP3 mRNA]
|
CTD |
PMID:16009159 PMID:17404688 PMID:18570937 PMID:19416213 PMID:22219637 PMID:26604029 PMID:27264040 More...
|
|
NCBI chr 8:12,925,267...12,938,828
Ensembl chr 8:12,925,280...12,938,826
|
|
| G
|
Mmp7
|
matrix metallopeptidase 7
|
multiple interactions decreases expression affects expression decreases secretion
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of MMP7 mRNA; [Estradiol co-treated with Progesterone] results in decreased secretion of MMP7 protein; Tetrachlorodibenzodioxin inhibits the reaction [Progesterone results in decreased secretion of MMP7 protein] Progesterone results in decreased expression of MMP7 mRNA Progesterone affects the expression of MMP7 mRNA
|
CTD |
PMID:16009159 PMID:17251523 PMID:20660070 PMID:22238285 |
|
NCBI chr 8:4,848,186...4,855,908
Ensembl chr 8:13,133,043...13,140,755
|
|
| G
|
Mmp8
|
matrix metallopeptidase 8
|
increases expression
|
EXP
|
Progesterone results in increased expression of MMP8 mRNA
|
CTD |
PMID:21770760 |
|
NCBI chr 8:4,724,009...4,733,864
Ensembl chr 8:13,008,890...13,018,729
|
|
| G
|
Mmp9
|
matrix metallopeptidase 9
|
multiple interactions increases expression
|
ISO EXP
|
[Progesterone co-treated with Estradiol] results in decreased expression of MMP9 mRNA; [Progesterone co-treated with Estradiol] results in increased expression of MMP9 mRNA; [Progesterone co-treated with Triclosan] results in increased expression of MMP9 mRNA; Progesterone inhibits the reaction [IL1B protein results in increased expression of MMP9 protein modified form] Progesterone results in increased expression of MMP9 mRNA Progesterone inhibits the reaction [Estradiol results in increased expression of MMP9 mRNA]
|
CTD |
PMID:17404688 PMID:19416213 PMID:20226447 PMID:21770760 PMID:22219637 PMID:26604029 More...
|
|
NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442
|
|
| G
|
Mmrn1
|
multimerin 1
|
increases expression
|
ISO
|
Progesterone results in increased expression of MMRN1 mRNA
|
CTD |
PMID:21540246 |
|
NCBI chr 4:89,875,408...89,950,814
Ensembl chr 4:91,233,240...91,280,861
|
|
| G
|
Mob3b
|
MOB kinase activator 3B
|
increases expression
|
ISO
|
Progesterone results in increased expression of MOB3B mRNA
|
CTD |
PMID:20864642 |
|
NCBI chr 5:54,342,509...54,534,164
Ensembl chr 5:54,338,056...54,454,678
|
|
| G
|
Mogat1
|
monoacylglycerol O-acyltransferase 1
|
multiple interactions decreases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of MOGAT1 mRNA Progesterone results in decreased expression of MOGAT1 mRNA
|
CTD |
PMID:19693291 PMID:22238285 |
|
NCBI chr 9:87,429,427...87,436,977
Ensembl chr 9:87,405,119...87,436,977
|
|
| G
|
Mogat2
|
monoacylglycerol O-acyltransferase 2
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of MOGAT2 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 1:153,521,813...153,545,756
Ensembl chr 1:162,933,966...162,957,896
|
|
| G
|
Mok
|
MOK protein kinase
|
increases expression
|
ISO
|
Progesterone results in increased expression of MOK mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 6:135,645,018...135,675,894
Ensembl chr 6:135,645,018...135,676,174
|
|
| G
|
Mon2
|
MON2 homolog, regulator of endosome-to-Golgi trafficking
|
increases expression
|
ISO
|
Progesterone results in increased expression of MON2 mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr 7:58,649,378...58,728,102
Ensembl chr 7:60,534,772...60,613,467
|
|
| G
|
Mpc1
|
mitochondrial pyruvate carrier 1
|
increases expression
|
EXP
|
Progesterone results in increased expression of MPC1 mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr 1:54,985,305...54,996,979
Ensembl chr 1:54,985,301...54,997,064
|
|
| G
|
Mpo
|
myeloperoxidase
|
multiple interactions
|
ISO
|
MPO gene polymorphism affects the reaction [[Estradiol co-treated with Progesterone] results in decreased expression of ICAM1 protein]
|
CTD |
PMID:21242819 |
|
NCBI chr10:72,594,883...72,608,862
Ensembl chr10:73,092,400...73,102,056
|
|
| G
|
Mpp1
|
MAGUK p55 scaffold protein 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of MPP1 mRNA
|
CTD |
PMID:20660070 |
|
|
|
| G
|
Mpz
|
myelin protein zero
|
increases expression multiple interactions
|
EXP
|
Progesterone results in increased expression of MPZ mRNA Progesterone inhibits the reaction [Streptozocin results in decreased expression of MPZ mRNA]
|
CTD |
PMID:16787508 PMID:17187935 |
|
NCBI chr13:86,103,290...86,109,156
Ensembl chr13:86,103,290...86,109,155
|
|
| G
|
Mpzl2
|
myelin protein zero-like 2
|
increases expression decreases expression multiple interactions
|
ISO
|
Progesterone results in increased expression of MPZL2 mRNA Progesterone results in decreased expression of MPZL2 mRNA NCOA2 protein affects the reaction [Progesterone results in decreased expression of MPZL2 mRNA]
|
CTD |
PMID:17404688 PMID:17556502 PMID:21540246 |
|
NCBI chr 8:54,244,920...54,256,064
Ensembl chr 8:54,243,556...54,256,074
|
|
| G
|
Mrap
|
melanocortin 2 receptor accessory protein
|
affects expression
|
ISO
|
Progesterone affects the expression of MRAP mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr11:29,991,974...30,003,024
Ensembl chr11:43,478,001...43,489,118
|
|
| G
|
Mras
|
muscle RAS oncogene homolog
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of MRAS mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 8:99,944,036...100,006,771
Ensembl chr 8:108,823,374...108,875,911
|
|
| G
|
Mrc1
|
mannose receptor, C type 1
|
multiple interactions
|
ISO
|
Progesterone inhibits the reaction [IL4 protein results in increased expression of MRC1 mRNA]
|
CTD |
PMID:21977998 |
|
NCBI chr17:82,157,725...82,239,411
Ensembl chr17:82,157,705...82,239,410
|
|
| G
|
Mrpl27
|
mitochondrial ribosomal protein L27
|
decreases expression multiple interactions
|
ISO
|
Progesterone results in decreased expression of MRPL27 mRNA [Estradiol co-treated with Progesterone] results in decreased expression of MRPL27 mRNA
|
CTD |
PMID:18037150 PMID:21453500 |
|
NCBI chr10:79,595,459...79,601,242
Ensembl chr10:80,092,324...80,098,085
|
|
| G
|
Mrpl30
|
mitochondrial ribosomal protein L30
|
affects expression
|
ISO
|
Progesterone affects the expression of MRPL30 mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr 9:40,125,352...40,136,189
Ensembl chr 9:47,621,227...47,633,484
|
|
| G
|
Mrpl49
|
mitochondrial ribosomal protein L49
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of MRPL49 mRNA
|
CTD |
PMID:21453500 |
|
NCBI chr 1:212,775,357...212,779,364
Ensembl chr 1:212,775,357...212,779,888
|
|
| G
|
Mrps28
|
mitochondrial ribosomal protein S28
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of MRPS28 mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr 2:92,820,676...92,951,302
Ensembl chr 2:94,762,904...94,766,152
|
|
| G
|
Mrps6
|
mitochondrial ribosomal protein S6
|
increases expression
|
ISO
|
Progesterone results in increased expression of MRPS6 mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr11:44,778,667...44,834,420
Ensembl chr11:44,781,554...44,834,962
|
|
| G
|
Mrto4
|
MRT4 homolog, ribosome maturation factor
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of MRTO4 mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr 5:151,601,780...151,608,533
Ensembl chr 5:156,884,985...156,891,738
|
|
| G
|
Msln
|
mesothelin
|
increases expression
|
ISO
|
Progesterone results in increased expression of MSLN mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr10:15,276,489...15,285,921
Ensembl chr10:15,275,659...15,282,153
|
|
| G
|
Msmo1
|
methylsterol monooxygenase 1
|
increases expression
|
ISO
|
Progesterone results in increased expression of MSMO1 mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr16:29,747,113...29,764,360
Ensembl chr16:29,747,137...29,764,445
|
|
| G
|
Mstn
|
myostatin
|
multiple interactions decreases expression
|
EXP
|
estradiol 3-benzoate promotes the reaction [Progesterone results in decreased expression of MSTN mRNA]
|
CTD |
PMID:18845635 |
|
NCBI chr 9:48,452,533...48,458,933
Ensembl chr 9:55,944,513...55,950,913
|
|
| G
|
Msx2
|
msh homeobox 2
|
multiple interactions decreases expression increases expression
|
ISO
|
[Estrogens co-treated with Progesterone] results in increased expression of MSX2 mRNA Progesterone results in decreased expression of MSX2 mRNA Progesterone results in increased expression of MSX2 mRNA
|
CTD |
PMID:17546050 PMID:22238285 |
|
NCBI chr17:11,097,214...11,102,879
Ensembl chr17:11,102,247...11,107,945
|
|
| G
|
Mt-atp8
|
mitochondrially encoded ATP synthase membrane subunit 8
|
increases expression
|
EXP
|
Progesterone results in increased expression of ATP8 mRNA
|
CTD |
PMID:21770760 |
|
NCBI chr MT:7,758...7,961
Ensembl chr MT:7,743...7,946
|
|
| G
|
Mt1-ps3
|
metallothionein 1, pseudogene 3
|
increases expression
|
ISO
|
Progesterone results in increased expression of MT1E mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr17:74,786,652...74,787,040
Ensembl chr17:79,695,809...79,696,200
|
|
| G
|
Mt1a
|
metallothionein 1A
|
increases expression affects expression
|
EXP ISO
|
Progesterone results in increased expression of MT1A mRNA Progesterone affects the expression of MT1 mRNA
|
CTD |
PMID:17251523 PMID:18037150 PMID:20726854 |
|
NCBI chr19:10,831,959...10,832,975
Ensembl chr17:79,695,809...79,696,200 Ensembl chr X:79,695,809...79,696,200 Ensembl chr19:79,695,809...79,696,200
|
|
| G
|
Mt2
|
metallothionein 2
|
increases expression affects expression
|
ISO
|
Progesterone results in increased expression of MT2A mRNA Progesterone results in increased expression of MT2 mRNA Progesterone affects the expression of MT2 mRNA
|
CTD |
PMID:17251523 PMID:18037150 PMID:21795739 PMID:22238285 |
|
NCBI chr19:10,837,934...10,838,708
Ensembl chr19:10,837,927...10,838,709
|
|
| G
|
Mta1
|
metastasis associated 1
|
increases expression
|
ISO
|
Progesterone results in increased expression of MTA1 mRNA
|
CTD |
PMID:16888808 |
|
NCBI chr 6:137,999,845...138,038,696
Ensembl chr 6:137,999,915...138,038,696
|
|
| G
|
Mtarc1
|
mitochondrial amidoxime reducing component 1
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of MTARC1 mRNA
|
CTD |
PMID:21540246 |
|
NCBI chr13:96,324,377...96,362,677
Ensembl chr13:98,871,289...98,894,252
|
|
| G
|
Mtf2
|
metal response element binding transcription factor 2
|
increases expression
|
ISO
|
Progesterone results in increased expression of MTF2 mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr14:1,639,256...1,683,513
Ensembl chr14:1,783,627...1,828,414
|
|
| G
|
Mthfd2
|
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
|
increases expression affects expression
|
ISO
|
Progesterone results in increased expression of MTHFD2 mRNA Progesterone affects the expression of MTHFD2 mRNA
|
CTD |
PMID:17251523 PMID:18037150 |
|
NCBI chr 4:117,368,833...117,380,350
Ensembl chr 4:117,368,835...117,380,350
|
|
| G
|
Mtor
|
mechanistic target of rapamycin kinase
|
decreases expression multiple interactions
|
ISO EXP
|
Progesterone results in decreased expression of MTOR mRNA [Estradiol co-treated with Progesterone co-treated with Methylnitrosourea] results in increased phosphorylation of MTOR protein
|
CTD |
PMID:22465879 PMID:23541542 |
|
NCBI chr 5:164,167,985...164,277,438
Ensembl chr 5:164,167,928...164,277,435
|
|
| G
|
Mtr
|
5-methyltetrahydrofolate-homocysteine methyltransferase
|
increases expression
|
ISO
|
Progesterone results in increased expression of MTR mRNA
|
CTD |
PMID:20864642 |
|
NCBI chr17:62,911,705...62,996,544
Ensembl chr17:62,911,771...62,996,541
|
|
| G
|
Mtus1
|
microtubule associated scaffold protein 1
|
increases expression
|
EXP
|
Progesterone results in increased expression of MTUS1 mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr16:57,905,991...58,051,466
Ensembl chr16:57,906,128...58,051,474
|
|
| G
|
Mtx1
|
Metaxin 1
|
affects expression
|
ISO
|
Progesterone affects the expression of MTX1 mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr 2:174,615,460...174,621,383
Ensembl chr 2:176,913,225...176,918,824
|
|
| G
|
Muc1
|
mucin 1, cell surface associated
|
affects expression
|
ISO
|
Progesterone affects the expression of MUC1 protein
|
CTD |
PMID:15971251 |
|
NCBI chr 2:174,635,989...174,640,738
Ensembl chr 2:176,933,047...176,938,491
|
|
| G
|
Muc20
|
mucin 20, cell surface associated
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of MUC20 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr11:81,492,844...81,506,571
Ensembl chr11:81,492,891...81,506,571
|
|
| G
|
Muc4
|
mucin 4, cell surface associated
|
multiple interactions decreases expression
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of MUC4 mRNA Progesterone results in decreased expression of MUC4 mRNA
|
CTD |
PMID:17404688 PMID:22238285 |
|
NCBI chr11:81,513,321...81,575,200
|
|
| G
|
Muc5b
|
mucin 5B, oligomeric mucus/gel-forming
|
increases expression
|
ISO
|
Progesterone results in increased expression of MUC5B mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr 1:196,916,861...196,948,830
Ensembl chr 1:206,346,400...206,378,367
|
|
| G
|
Mvk
|
mevalonate kinase
|
increases expression
|
ISO
|
Progesterone results in increased expression of MVK mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr12:47,802,002...47,819,503
Ensembl chr12:47,802,002...47,819,503
|
|
| G
|
Myadm
|
myeloid-associated differentiation marker
|
increases expression
|
ISO
|
Progesterone results in increased expression of MYADM mRNA
|
CTD |
PMID:21795739 |
|
NCBI chr 1:65,864,180...65,874,701
Ensembl chr 1:74,775,698...74,789,710
|
|
| G
|
Myb
|
MYB proto-oncogene, transcription factor
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of MYB mRNA
|
CTD |
PMID:16966611 PMID:18497975 PMID:22238285 |
|
NCBI chr 1:15,939,771...15,973,367
Ensembl chr 1:17,759,309...17,792,547
|
|
| G
|
Mybl1
|
MYB proto-oncogene like 1
|
increases expression multiple interactions
|
ISO
|
Progesterone results in increased expression of MYBL1 mRNA Fulvestrant inhibits the reaction [Progesterone results in increased expression of MYBL1 mRNA]
|
CTD |
PMID:33405908 |
|
NCBI chr 5:14,365,768...14,401,012
Ensembl chr 5:14,365,768...14,399,588
|
|
| G
|
Mybl2
|
MYB proto-oncogene like 2
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of MYBL2 mRNA
|
CTD |
PMID:16966611 |
|
NCBI chr 3:151,705,254...151,733,714
Ensembl chr 3:172,116,550...172,153,221
|
|
| G
|
Mybpc1
|
myosin binding protein C1
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of MYBPC1 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 7:22,930,350...23,015,981
Ensembl chr 7:24,817,561...24,903,544
|
|
| G
|
Mybpc2
|
myosin binding protein C2
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of MYBPC2 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 1:104,130,642...104,154,101
Ensembl chr 1:104,131,323...104,154,101
|
|
| G
|
Myc
|
MYC proto-oncogene, bHLH transcription factor
|
decreases expression increases expression multiple interactions
|
ISO
|
Progesterone results in decreased expression of MYC protein Progesterone results in increased expression of MYC mRNA; Progesterone results in increased expression of MYC protein [5-(4-ethylbenzylidene)-2-thioxothiazolidin-4-one results in decreased activity of MYC protein] inhibits the reaction [Progesterone results in increased expression of RRM2 mRNA]; [Estradiol co-treated with Progesterone] results in increased expression of MYC mRNA; MYC protein promotes the reaction [Progesterone results in increased expression of RRM2 mRNA]; Progesterone promotes the reaction [Estradiol results in increased expression of MYC mRNA]
|
CTD |
PMID:8390853 PMID:18045962 PMID:18556351 PMID:19847363 PMID:21795739 PMID:22403396 More...
|
|
NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:95,483,105...95,488,028
|
|
| G
|
Mycl
|
MYCL proto-oncogene, bHLH transcription factor
|
affects expression
|
ISO
|
Progesterone affects the expression of MYCL mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr 5:140,559,843...140,566,704
Ensembl chr 5:140,560,152...140,566,699
|
|
| G
|
Mycn
|
MYCN proto-oncogene, bHLH transcription factor
|
multiple interactions decreases expression
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of MYCN mRNA Progesterone results in decreased expression of MYCN mRNA
|
CTD |
PMID:17404688 PMID:22238285 |
|
NCBI chr 6:41,446,683...41,452,584
Ensembl chr 6:41,446,684...41,452,508
|
|
| G
|
Myd88
|
MYD88, innate immune signal transduction adaptor
|
increases expression
|
ISO
|
Progesterone results in increased expression of MYD88 mRNA
|
CTD |
PMID:21549006 |
|
NCBI chr 8:127,952,161...127,956,230
Ensembl chr 8:127,952,161...127,956,230
|
|
| G
|
Myh1
|
myosin heavy chain 1
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of MYH1 mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr10:52,384,810...52,408,698
Ensembl chr10:52,384,908...52,409,047
|
|
| G
|
Myh10
|
myosin heavy chain 10
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of MYH10 mRNA
|
CTD |
PMID:21795739 |
|
NCBI chr10:53,393,901...53,525,174
Ensembl chr10:53,893,166...54,024,036
|
|
| G
|
Myh11
|
myosin heavy chain 11
|
increases expression
|
EXP
|
Progesterone results in increased expression of MYH11 mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr10:743,364...838,459
Ensembl chr10:1,263,194...1,345,678
|
|
| G
|
Myh3
|
myosin heavy chain 3
|
decreases expression
|
EXP
|
Progesterone results in decreased expression of MYH3 mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr10:51,770,177...51,793,994
Ensembl chr10:52,269,185...52,293,000
|
|
| G
|
Myh6
|
myosin heavy chain 6
|
increases expression
|
EXP ISO
|
Progesterone results in increased expression of MYH6 mRNA
|
CTD |
PMID:20726854 PMID:22238285 |
|
NCBI chr15:32,388,102...32,413,663
Ensembl chr15:32,387,487...32,411,333
|
|
| G
|
Myh7
|
myosin heavy chain 7
|
increases expression
|
EXP
|
Progesterone results in increased expression of MYH7 mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr15:32,416,525...32,439,851
Ensembl chr15:32,416,527...32,438,194
|
|
| G
|
Myl1
|
myosin, light chain 1
|
increases expression
|
EXP
|
Progesterone results in increased expression of MYL1 mRNA
|
CTD |
PMID:20726854 |
|
Ensembl chr 9:75,887,227...75,907,971
|
|
| G
|
Myl6b
|
myosin light chain 6B
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of MYL6B mRNA
|
CTD |
PMID:21795739 |
|
NCBI chr X:40,572,012...40,572,991
|
|
| G
|
Myl9
|
myosin light chain 9
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of MYL9 mRNA
|
CTD |
PMID:18037150 PMID:18070364 |
|
NCBI chr 3:165,742,020...165,748,409
Ensembl chr 3:165,742,046...165,748,410
|
|
| G
|
Mylip
|
myosin regulatory light chain interacting protein
|
increases expression decreases expression
|
ISO
|
Progesterone results in increased expression of MYLIP mRNA Progesterone results in decreased expression of MYLIP mRNA
|
CTD |
PMID:18037150 PMID:21795739 |
|
NCBI chr17:19,492,826...19,514,490
Ensembl chr17:19,492,826...19,514,471
|
|
| G
|
Mylk
|
myosin light chain kinase
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of MYLK mRNA; [Progesterone co-treated with Estradiol] results in decreased expression of MYLK mRNA
|
CTD |
PMID:17404688 PMID:20660070 |
|
NCBI chr11:65,783,008...66,030,239
Ensembl chr11:79,288,243...79,535,659
|
|
| G
|
Mylk3
|
myosin light chain kinase 3
|
multiple interactions decreases expression
|
ISO
|
Mifepristone inhibits the reaction [Progesterone results in decreased expression of MYLK3 mRNA]
|
CTD |
PMID:27264040 PMID:31566189 |
|
NCBI chr19:37,858,298...37,916,805
Ensembl chr19:37,865,141...37,915,827
|
|
| G
|
Myo16
|
myosin XVI
|
increases expression
|
ISO
|
Progesterone results in increased expression of MYO16 mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr16:85,586,428...86,066,537
Ensembl chr16:85,586,429...85,973,879
|
|
| G
|
Myo1b
|
myosin Ib
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of MYO1B mRNA
|
CTD |
PMID:20864642 |
|
NCBI chr 9:57,182,059...57,344,335
Ensembl chr 9:57,181,987...57,344,328
|
|
| G
|
Myocd
|
myocardin
|
increases expression
|
ISO
|
Progesterone results in increased expression of MYOCD mRNA
|
CTD |
PMID:20864642 |
|
NCBI chr10:50,332,356...50,426,819
Ensembl chr10:50,332,356...50,426,819
|
|
| G
|
Myof
|
myoferlin
|
decreases expression multiple interactions
|
ISO
|
Progesterone results in decreased expression of MYOF mRNA [Estradiol co-treated with Progesterone] results in increased expression of MYOF mRNA
|
CTD |
PMID:18037150 PMID:20660070 |
|
NCBI chr 1:245,086,109...245,234,768
Ensembl chr 1:245,086,109...245,234,768
|
|
| G
|
Myrip
|
myosin VIIA and Rab interacting protein
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of MYRIP mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 8:128,895,371...129,062,420
Ensembl chr 8:128,895,371...129,062,420
|
|
| G
|
Naaa
|
N-acylethanolamine acid amidase
|
increases expression multiple interactions
|
ISO
|
Progesterone results in increased expression of NAAA mRNA [Estradiol co-treated with Progesterone] results in increased expression of NAAA mRNA
|
CTD |
PMID:17404688 PMID:20660070 |
|
NCBI chr14:16,061,599...16,080,703
Ensembl chr14:16,061,583...16,080,702
|
|
| G
|
Nacc2
|
NACC family member 2
|
affects expression increases expression
|
ISO
|
Progesterone affects the expression of NACC2 mRNA Progesterone results in increased expression of NACC2 mRNA
|
CTD |
PMID:17251523 PMID:22238285 |
|
NCBI chr 3:8,879,952...8,946,660
Ensembl chr 3:29,281,190...29,344,840
|
|
| G
|
Nalcn
|
sodium leak channel, non-selective
|
increases expression
|
ISO
|
Progesterone results in increased expression of NALCN mRNA
|
CTD |
PMID:21795739 |
|
NCBI chr15:100,398,583...100,741,243
Ensembl chr15:106,805,209...107,147,858
|
|
| G
|
Nalf1
|
NALCN channel auxiliary factor 1
|
increases expression
|
ISO
|
Progesterone results in increased expression of NALF1 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr16:79,713,577...80,236,295
Ensembl chr16:86,415,488...86,938,150
|
|
| G
|
Nampt
|
nicotinamide phosphoribosyltransferase
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] promotes the reaction [Estriol results in increased expression of NAMPT mRNA] NAMPT protein promotes the reaction [IGF1 protein results in increased abundance of Progesterone]
|
CTD |
PMID:20004694 PMID:23315983 |
|
NCBI chr 6:55,152,756...55,189,547
Ensembl chr 6:55,151,926...55,189,544
|
|
| G
|
Nanos1
|
nanos C2HC-type zinc finger 1
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of NANOS1 mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr 1:269,883,713...269,887,611
Ensembl chr 1:269,883,536...269,895,417
|
|
| G
|
Napsa
|
napsin A aspartic peptidase
|
affects expression
|
ISO
|
Progesterone affects the expression of NAPSA mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr 1:104,200,967...104,213,603
Ensembl chr 1:104,200,960...104,213,608
|
|
| G
|
Nat1
|
N-acetyltransferase 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of NAT1 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr16:26,984,882...27,005,194
Ensembl chr16:26,982,625...26,986,527
|
|
| G
|
Nav3
|
neuron navigator 3
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of NAV3 mRNA
|
CTD |
PMID:20864642 |
|
NCBI chr 7:46,938,577...47,726,839
Ensembl chr 7:46,940,670...47,504,893
|
|
| G
|
Ncapg
|
non-SMC condensin I complex, subunit G
|
increases expression decreases expression
|
ISO
|
Progesterone results in increased expression of NCAPG mRNA Progesterone results in decreased expression of NCAPG mRNA
|
CTD |
PMID:18070364 PMID:21795739 |
|
NCBI chr14:69,616,473...69,645,445
Ensembl chr14:69,616,473...69,645,445
|
|
| G
|
Ncf2
|
neutrophil cytosolic factor 2
|
increases expression multiple interactions
|
ISO
|
Progesterone results in increased expression of NCF2 mRNA Estradiol inhibits the reaction [Progesterone results in increased expression of NCF2 mRNA]
|
CTD |
PMID:16195479 |
|
NCBI chr13:67,505,492...67,536,015
Ensembl chr13:67,505,375...67,536,149
|
|
| G
|
Nck1
|
NCK adaptor protein 1
|
increases expression
|
EXP
|
Progesterone results in increased expression of NCK1 mRNA
|
CTD |
PMID:21770760 |
|
NCBI chr 8:101,018,610...101,079,237
Ensembl chr 8:109,897,724...109,958,247
|
|
| G
|
Ncmap
|
noncompact myelin associated protein
|
multiple interactions decreases expression
|
ISO
|
Mifepristone promotes the reaction [Progesterone affects the expression of NCMAP mRNA] Progesterone results in decreased expression of NCMAP mRNA
|
CTD |
PMID:22238285 PMID:22414680 |
|
NCBI chr 5:152,893,173...152,921,175
Ensembl chr 5:152,894,316...152,902,414
|
|
| G
|
Ncoa1
|
nuclear receptor coactivator 1
|
increases expression multiple interactions
|
ISO
|
Progesterone results in increased expression of NCOA1 protein [Progesterone co-treated with Estradiol] inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime promotes the reaction [[NR1I3 protein co-treated with FOXO1 protein co-treated with HNF4A protein co-treated with NCOA1 protein] binds to CYP2C9 promoter]]; Progesterone inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime promotes the reaction [[NR1I3 protein co-treated with FOXO1 protein co-treated with HNF4A protein co-treated with NCOA1 protein] binds to CYP2C9 promoter]]
|
CTD |
PMID:17556502 PMID:21768169 |
|
NCBI chr 6:32,952,090...33,229,829
Ensembl chr 6:32,952,090...33,195,924
|
|
| G
|
Ncoa2
|
nuclear receptor coactivator 2
|
multiple interactions increases expression
|
ISO
|
NCOA2 protein affects the reaction [Progesterone results in decreased expression of BMP2 mRNA]; NCOA2 protein affects the reaction [Progesterone results in decreased expression of BMP5 mRNA]; NCOA2 protein affects the reaction [Progesterone results in decreased expression of CALB1 mRNA]; NCOA2 protein affects the reaction [Progesterone results in decreased expression of CDKL1 mRNA]; NCOA2 protein affects the reaction [Progesterone results in decreased expression of CLMN mRNA]; NCOA2 protein affects the reaction [Progesterone results in decreased expression of DSP mRNA]; NCOA2 protein affects the reaction [Progesterone results in decreased expression of EMB mRNA]; NCOA2 protein affects the reaction [Progesterone results in decreased expression of HMGA2 mRNA]; NCOA2 protein affects the reaction [Progesterone results in decreased expression of KRT18 mRNA]; NCOA2 protein affects the reaction [Progesterone results in decreased expression of LDB2 mRNA]; NCOA2 protein affects the reaction [Progesterone results in decreased expression of MPZL2 mRNA]; NCOA2 protein affects the reaction [Progesterone results in decreased expression of POF1B mRNA]; NCOA2 protein affects the reaction [Progesterone results in decreased expression of RHPN2 mRNA]; NCOA2 protein affects the reaction [Progesterone results in decreased expression of S100G mRNA]; NCOA2 protein affects the reaction [Progesterone results in decreased expression of SLC44A3 mRNA]; NCOA2 protein affects the reaction [Progesterone results in decreased expression of SOX7 mRNA]; NCOA2 protein affects the reaction [Progesterone results in decreased expression of TJP3 mRNA]; NCOA2 protein affects the reaction [Progesterone results in decreased expression of TSPAN8 mRNA]; NCOA2 protein affects the reaction [Progesterone results in decreased expression of WNT7A mRNA]; NCOA2 protein affects the reaction [Progesterone results in increased expression of ATP2C2 mRNA]; NCOA2 protein affects the reaction [Progesterone results in increased expression of CLDN23 mRNA]; NCOA2 protein affects the reaction [Progesterone results in increased expression of SLCO5A1 mRNA]; NCOA2 protein affects the reaction [Progesterone results in increased expression of TTR mRNA]; NCOA2 protein affects the reaction [Progesterone results in increased expression of TUBB2A mRNA] Progesterone results in increased expression of NCOA2 protein
|
CTD |
PMID:17556502 |
|
NCBI chr 5:5,835,642...6,069,693
Ensembl chr 5:10,618,722...10,852,776
|
|
| G
|
Ncoa4
|
nuclear receptor coactivator 4
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of NCOA4 mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr16:7,389,222...7,409,564
Ensembl chr16:7,401,802...7,415,840
|
|
| G
|
Ncr2
|
natural cytotoxicity triggering receptor 2
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in increased expression of NCR2 mRNA
|
CTD |
PMID:18692832 |
|
NCBI chr 9:12,777,195...12,828,437
|
|
| G
|
Ndc80
|
NDC80 kinetochore complex component
|
increases expression
|
ISO
|
Progesterone results in increased expression of NDC80 mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr 9:118,853,806...118,887,582
Ensembl chr 9:118,853,806...118,887,568
|
|
| G
|
Ndp
|
norrin cystine knot growth factor NDP
|
multiple interactions increases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of NDP mRNA; [Progesterone co-treated with Estradiol] results in increased expression of NDP mRNA Progesterone results in increased expression of NDP mRNA
|
CTD |
PMID:17404688 PMID:20660070 PMID:22238285 |
|
NCBI chr X:5,796,487...5,820,934
Ensembl chr X:8,379,569...8,406,802
|
|
| G
|
Ndrg1
|
N-myc downstream regulated 1
|
increases expression
|
ISO
|
Progesterone results in increased expression of NDRG1 mRNA
|
CTD |
PMID:21795739 |
|
NCBI chr 7:98,684,487...98,725,869
Ensembl chr 7:100,573,523...100,614,913
|
|
| G
|
Ndrg2
|
NDRG family member 2
|
decreases expression increases expression
|
ISO EXP
|
Progesterone results in decreased expression of NDRG2 mRNA Progesterone results in increased expression of NDRG2 mRNA
|
CTD |
PMID:20726854 PMID:21540246 |
|
NCBI chr15:27,074,481...27,087,376
Ensembl chr15:27,074,481...27,083,125
|
|
| G
|
Ndrg4
|
NDRG family member 4
|
increases expression
|
EXP
|
Progesterone results in increased expression of NDRG4 mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr19:9,351,408...9,387,398
Ensembl chr19:9,357,470...9,392,972
|
|
| G
|
Ndufb7
|
NADH:ubiquinone oxidoreductase subunit B7
|
increases expression
|
ISO
|
Progesterone results in increased expression of NDUFB7 mRNA
|
CTD |
PMID:38992643 |
|
NCBI chr19:41,472,953...41,477,291
Ensembl chr19:41,472,953...41,477,291
|
|
| G
|
Nebl
|
nebulette
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of NEBL mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr17:85,022,953...85,374,848
Ensembl chr17:85,022,963...85,374,172
|
|
| G
|
Nefh
|
neurofilament heavy chain
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of NEFH mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr14:84,044,428...84,054,413
Ensembl chr14:84,044,023...84,054,417
|
|
| G
|
Nefm
|
neurofilament medium chain
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of NEFM mRNA
|
CTD |
PMID:20864642 |
|
NCBI chr15:46,535,857...46,541,161
Ensembl chr15:46,535,517...46,541,163
|
|
| G
|
Negr1
|
neuronal growth regulator 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of NEGR1 mRNA
|
CTD |
PMID:21453500 |
|
NCBI chr 2:245,624,460...246,359,605
Ensembl chr 2:248,283,353...249,018,410
|
|
| G
|
Nek2
|
NIMA-related kinase 2
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of NEK2 mRNA
|
CTD |
PMID:21795739 |
|
NCBI chr13:105,936,809...105,950,054
Ensembl chr13:105,936,788...105,950,056
|
|
| G
|
Nell2
|
neural EGFL like 2
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of NELL2 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 7:128,222,333...128,542,127
Ensembl chr 7:128,078,103...128,651,917
|
|
| G
|
Neo1
|
neogenin 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of NEO1 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 8:59,273,860...59,426,486
Ensembl chr 8:68,169,716...68,322,152
|
|
| G
|
Nes
|
nestin
|
decreases expression
|
ISO EXP
|
Progesterone results in decreased expression of NES mRNA
|
CTD |
PMID:20726854 PMID:21795739 |
|
NCBI chr 2:175,735,715...175,745,631
Ensembl chr 2:175,736,551...175,746,228
|
|
| G
|
Neu3
|
neuraminidase 3
|
increases expression
|
EXP
|
Progesterone results in increased expression of NEU3 mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr 1:163,549,834...163,560,997
Ensembl chr 1:163,549,738...163,561,049
|
|
| G
|
Nexn
|
nexilin (F actin binding protein)
|
increases expression
|
EXP
|
Progesterone results in increased expression of NEXN mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr 2:241,186,783...241,218,315
Ensembl chr 2:243,846,433...243,887,114
|
|
| G
|
Nfat5
|
nuclear factor of activated T-cells 5
|
decreases expression
|
EXP
|
Progesterone results in decreased expression of NFAT5 mRNA
|
CTD |
PMID:21371490 |
|
NCBI chr19:52,108,982...52,196,418
Ensembl chr19:52,109,483...52,196,418
|
|
| G
|
Nfe2l2
|
NFE2 like bZIP transcription factor 2
|
affects expression
|
EXP
|
Progesterone affects the expression of NFE2L2 mRNA
|
CTD |
PMID:24777823 |
|
NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090
|
|
| G
|
Nfib
|
nuclear factor I/B
|
multiple interactions increases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of NFIB mRNA; [Progesterone co-treated with Estradiol] results in increased expression of NFIB mRNA Progesterone results in increased expression of NFIB mRNA
|
CTD |
PMID:17404688 PMID:20660070 |
|
NCBI chr 5:101,805,168...102,020,618
Ensembl chr 5:101,805,168...102,019,945
|
|
| G
|
Nfic
|
nuclear factor I/C
|
affects expression
|
ISO
|
Progesterone affects the expression of NFIC mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr 7:8,278,210...8,309,936
Ensembl chr 7:8,904,117...8,963,409
|
|
| G
|
Nfil3
|
nuclear factor, interleukin 3 regulated
|
increases expression
|
ISO
|
Progesterone results in increased expression of NFIL3 mRNA
|
CTD |
PMID:20864642 PMID:21795739 |
|
NCBI chr17:12,432,376...12,447,605
Ensembl chr17:12,432,198...12,450,826
|
|
| G
|
Nfix
|
nuclear factor I X
|
affects expression
|
ISO
|
Progesterone affects the expression of NFIX mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr19:40,259,873...40,356,966
Ensembl chr19:40,260,084...40,353,092
|
|
| G
|
Nfkb1
|
nuclear factor kappa B subunit 1
|
multiple interactions
|
ISO
|
Mifepristone inhibits the reaction [Progesterone inhibits the reaction [[Estradiol co-treated with TNF protein] results in increased activity of NFKB1 protein]]; Progesterone inhibits the reaction [[Estradiol co-treated with TNF protein] results in increased activity of NFKB1 protein]
|
CTD |
PMID:15866594 |
|
NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:226,689,745...226,783,088
|
|
| G
|
Nfkb2
|
nuclear factor kappa B subunit 2
|
increases expression
|
ISO
|
Progesterone results in increased expression of NFKB2 mRNA
|
CTD |
PMID:21549006 |
|
NCBI chr 1:255,106,010...255,114,649
Ensembl chr 1:255,107,374...255,114,637
|
|
| G
|
Nfkbia
|
NFKB inhibitor alpha
|
multiple interactions increases expression
|
ISO EXP
|
Progesterone inhibits the reaction [IL1B protein results in increased degradation of NFKBIA protein] Progesterone results in increased expression of NFKBIA mRNA Progesterone promotes the reaction [Hydrogen Peroxide results in increased degradation of NFKBIA protein]
|
CTD |
PMID:16284289 PMID:17437195 PMID:18037150 PMID:21795739 |
|
NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:78,593,847...78,597,072
|
|
| G
|
Nfkbil1
|
NFKB inhibitor like 1
|
increases expression
|
ISO
|
Progesterone results in increased expression of NFKBIL1 mRNA
|
CTD |
PMID:21549006 |
|
NCBI chr20:3,595,319...3,610,295
Ensembl chr20:3,595,284...3,610,294
|
|
| G
|
Nfkbiz
|
NFKB inhibitor zeta
|
increases expression
|
ISO
|
Progesterone results in increased expression of NFKBIZ mRNA
|
CTD |
PMID:21795739 |
|
NCBI chr11:58,251,720...58,279,767
Ensembl chr11:58,251,721...58,279,767
|
|
| G
|
Nfxl1
|
nuclear transcription factor, X-box binding-like 1
|
increases expression
|
ISO
|
Progesterone results in increased expression of NFXL1 mRNA
|
CTD |
PMID:21795739 |
|
NCBI chr14:35,626,086...35,667,505
Ensembl chr14:35,980,057...36,023,281
|
|
| G
|
Ngf
|
nerve growth factor
|
multiple interactions
|
EXP
|
[Estradiol co-treated with Progesterone] results in decreased expression of NGF mRNA; [VIP protein results in increased secretion of Progesterone] which results in decreased expression of NGF mRNA; Progesterone inhibits the reaction [Estradiol results in increased expression of NGF protein]
|
CTD |
PMID:15570173 PMID:20150881 PMID:21277368 |
|
NCBI chr 2:192,589,580...192,642,971
Ensembl chr 2:192,589,582...192,643,834
|
|
| G
|
Ngly1
|
N-glycanase 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of NGLY1 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr15:9,153,738...9,210,228
Ensembl chr15:11,584,475...11,635,328
|
|
| G
|
Nherf1
|
NHERF family PDZ scaffold protein 1
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of NHERF1 mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr10:100,902,165...100,919,265
Ensembl chr10:100,901,227...100,919,579
|
|
| G
|
Niban1
|
niban apoptosis regulator 1
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of NIBAN1 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr13:66,224,219...66,377,728
Ensembl chr13:66,224,021...66,377,724
|
|
| G
|
Nid1
|
nidogen 1
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of NID1 mRNA
|
CTD |
PMID:19693291 |
|
NCBI chr17:93,069,013...93,142,416
Ensembl chr17:93,069,278...93,142,386
|
|
| G
|
Nit1
|
nitrilase 1
|
affects expression
|
ISO
|
Progesterone affects the expression of NIT1 mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr13:86,302,334...86,305,770
Ensembl chr13:86,298,387...86,305,770
|
|
| G
|
Nkg7
|
natural killer cell granule protein 7
|
increases expression
|
ISO
|
Progesterone results in increased expression of NKG7 mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr 1:102,981,497...102,982,564
Ensembl chr 1:102,981,450...102,982,562
|
|
| G
|
Nlrp5
|
NLR family, pyrin domain containing 5
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of NLRP5 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 1:67,778,037...67,810,941
Ensembl chr 1:76,810,108...77,077,580
|
|
| G
|
Nmb
|
neuromedin B
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of NMB mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr 1:144,278,678...144,290,523
Ensembl chr 1:144,278,453...144,281,422
|
|
| G
|
Nme2
|
NME/NM23 nucleoside diphosphate kinase 2
|
increases expression multiple interactions
|
ISO
|
Progesterone results in increased expression of NME2 mRNA Mifepristone inhibits the reaction [Progesterone results in increased expression of NME2 mRNA]
|
CTD |
PMID:15674352 |
|
NCBI chr10:79,394,999...79,400,418
Ensembl chr20:11,179,066...11,179,497 Ensembl chr10:11,179,066...11,179,497
|
|
| G
|
Nmt1
|
N-myristoyltransferase 1
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of NMT1 mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr10:87,988,826...88,025,405
Ensembl chr10:88,488,990...88,522,729
|
|
| G
|
Nmu
|
neuromedin U
|
increases abundance
|
EXP
|
NMU protein results in increased abundance of Progesterone
|
CTD |
PMID:23423171 |
|
NCBI chr14:31,844,564...31,872,196
Ensembl chr14:32,198,943...32,226,632
|
|
| G
|
Nodal
|
nodal growth differentiation factor
|
decreases expression
|
EXP
|
Progesterone results in decreased expression of NODAL mRNA
|
CTD |
PMID:21770760 |
|
NCBI chr20:29,911,258...29,919,659
Ensembl chr20:29,911,258...29,919,659
|
|
| G
|
Nog
|
noggin
|
multiple interactions
|
ISO EXP
|
NOG protein inhibits the reaction [BMP2 protein results in decreased abundance of Progesterone]; Progesterone promotes the reaction [Estradiol results in increased expression of NOG mRNA] NOG protein promotes the reaction [GH1 protein promotes the reaction [FSHB protein results in increased abundance of Progesterone]] NOG protein inhibits the reaction [Octreotide inhibits the reaction [FSHB protein results in increased abundance of Progesterone]]; NOG protein inhibits the reaction [pasireotide inhibits the reaction [FSHB protein results in increased abundance of Progesterone]]
|
CTD |
PMID:20639315 PMID:21795739 PMID:22067323 PMID:23137853 |
|
NCBI chr10:74,625,874...74,627,501
Ensembl chr10:74,625,875...74,628,103
|
|
| G
|
Nop56
|
NOP56 ribonucleoprotein
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of NOP56 mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr 3:137,926,187...137,934,971
Ensembl chr 3:137,929,646...137,934,959
|
|
| G
|
Nos1
|
nitric oxide synthase 1
|
multiple interactions decreases expression
|
EXP ISO
|
[Progesterone co-treated with estradiol 3-benzoate] results in increased expression of NOS1 protein Progesterone results in decreased expression of NOS1 protein
|
CTD |
PMID:15347845 PMID:22486171 |
|
NCBI chr12:44,276,011...44,456,371
Ensembl chr12:44,287,614...44,371,837
|
|
| G
|
Nos2
|
nitric oxide synthase 2
|
multiple interactions decreases expression affects response to substance increases expression
|
ISO EXP
|
Mifepristone inhibits the reaction [Progesterone results in increased expression of NOS2 mRNA]; Mifepristone inhibits the reaction [Progesterone results in increased expression of NOS2 protein] Progesterone results in decreased expression of NOS2 mRNA [VIP protein results in increased secretion of Progesterone] which results in decreased expression of NOS2 protein Progesterone inhibits the reaction [[Lipopolysaccharides co-treated with IL4 protein] results in increased expression of NOS2 mRNA]; Progesterone inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; Progesterone inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] NOS2 protein affects the susceptibility to Progesterone Progesterone results in increased expression of NOS2 mRNA; Progesterone results in increased expression of NOS2 protein
|
CTD |
PMID:11063824 PMID:15869954 PMID:16399999 PMID:18710710 PMID:20150881 PMID:21977998 More...
|
|
NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880
|
|
| G
|
Nos3
|
nitric oxide synthase 3
|
multiple interactions decreases expression increases expression increases activity increases phosphorylation
|
ISO EXP
|
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Progesterone promotes the reaction [Estradiol results in increased activity of NOS3 protein]]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Progesterone results in increased activity of NOS3 protein]; Mifepristone inhibits the reaction [Progesterone promotes the reaction [Estradiol results in increased activity of NOS3 protein]]; Mifepristone inhibits the reaction [Progesterone results in increased expression of and results in increased phosphorylation of NOS3 protein]; Mifepristone inhibits the reaction [Progesterone results in increased expression of NOS3 mRNA]; Mifepristone inhibits the reaction [Progesterone results in increased expression of NOS3 protein]; Org 31710 inhibits the reaction [Progesterone results in increased expression of NOS3 protein]; Org 31710 inhibits the reaction [Progesterone results in increased phosphorylation of NOS3 protein]; Progesterone promotes the reaction [Estradiol results in increased activity of NOS3 protein]; Progesterone results in increased expression of and results in increased phosphorylation of NOS3 protein; U 0126 inhibits the reaction [Progesterone results in increased phosphorylation of NOS3 protein]; Wortmannin inhibits the reaction [Progesterone promotes the reaction [Estradiol results in increased activity of NOS3 protein]]; Wortmannin inhibits the reaction [Progesterone results in increased activity of NOS3 protein]; Wortmannin inhibits the reaction [Progesterone results in increased phosphorylation of NOS3 protein] Progesterone results in decreased expression of NOS3 protein Progesterone results in increased expression of NOS3 mRNA; Progesterone results in increased expression of NOS3 protein
|
CTD |
PMID:15358673 PMID:18710710 PMID:21558462 |
|
NCBI chr 4:11,686,088...11,706,604
Ensembl chr 4:11,686,268...11,706,664
|
|
| G
|
Notch1
|
notch receptor 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of NOTCH1 mRNA
|
CTD |
PMID:19693291 |
|
NCBI chr 3:29,676,040...29,721,613
Ensembl chr 3:29,676,171...29,721,613
|
|
| G
|
Notch2
|
notch receptor 2
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of NOTCH2 mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr 2:188,299,336...188,432,823
Ensembl chr 2:188,299,336...188,432,823
|
|
| G
|
Nox3
|
NADPH oxidase 3
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of NOX3 mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr 1:44,238,012...44,302,851
Ensembl chr 1:46,642,564...46,708,109
|
|
| G
|
Noxa1
|
NADPH oxidase activator 1
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of NOXA1 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 3:28,293,643...28,309,828
Ensembl chr 3:28,293,658...28,304,022
|
|
| G
|
Npas2
|
neuronal PAS domain protein 2
|
increases expression
|
ISO
|
Progesterone results in increased expression of NPAS2 mRNA
|
CTD |
PMID:21795739 |
|
NCBI chr 9:48,959,225...49,138,036
Ensembl chr 9:48,959,148...49,138,037
|
|
| G
|
Npc1
|
NPC intracellular cholesterol transporter 1
|
multiple interactions
|
ISO
|
Progesterone inhibits the reaction [NPC1 protein results in increased secretion of Cholesterol]; Progesterone inhibits the reaction [NPC1 protein results in increased secretion of Daunorubicin]
|
CTD |
PMID:16174794 |
|
NCBI chr18:3,654,237...3,699,853
Ensembl chr18:3,654,237...3,699,800
|
|
| G
|
Npl
|
N-acetylneuraminate pyruvate lyase
|
affects expression
|
ISO
|
Progesterone affects the expression of NPL mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr13:68,205,602...68,247,940
Ensembl chr13:68,205,603...68,247,999
|
|
| G
|
Npm3
|
nucleophosmin/nucleoplasmin, 3
|
affects expression
|
ISO
|
Progesterone affects the expression of NPM3 mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr 1:254,544,664...254,546,649
Ensembl chr 1:254,544,664...254,546,649
|
|
| G
|
Nppa
|
natriuretic peptide A
|
increases expression multiple interactions
|
EXP ISO
|
Progesterone results in increased expression of NPPA mRNA [Progesterone co-treated with Estradiol] results in increased expression of NPPA mRNA
|
CTD |
PMID:18692832 PMID:20726854 |
|
NCBI chr 5:163,712,184...163,713,493
Ensembl chr 5:163,712,184...163,713,493
|
|
| G
|
Nppb
|
natriuretic peptide B
|
increases expression
|
EXP
|
Progesterone results in increased expression of NPPB mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr 5:163,699,955...163,701,314
Ensembl chr 5:163,699,839...163,701,310
|
|
| G
|
Nppc
|
natriuretic peptide C
|
multiple interactions increases expression
|
ISO
|
Progesterone inhibits the reaction [Estradiol results in increased expression of NPPC protein] Progesterone results in increased expression of NPPC mRNA
|
CTD |
PMID:9435603 PMID:22238285 |
|
NCBI chr 9:94,767,986...94,772,186
Ensembl chr 9:94,767,986...94,772,186
|
|
| G
|
Npr3
|
natriuretic peptide receptor 3
|
increases expression
|
ISO
|
Progesterone results in increased expression of NPR3 mRNA
|
CTD |
PMID:20864642 |
|
NCBI chr 2:62,592,557...62,660,497
Ensembl chr 2:62,597,668...62,660,066
|
|
| G
|
Nptx2
|
neuronal pentraxin 2
|
multiple interactions increases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of NPTX2 mRNA; [Progesterone co-treated with Estradiol] results in increased expression of NPTX2 mRNA Progesterone results in increased expression of NPTX2 mRNA
|
CTD |
PMID:17404688 PMID:20660070 |
|
NCBI chr12:10,037,435...10,048,345
Ensembl chr12:15,151,136...15,162,045
|
|
| G
|
Npy
|
neuropeptide Y
|
increases expression decreases expression increases secretion
|
ISO EXP
|
Progesterone results in increased expression of NPY mRNA Progesterone results in decreased expression of NPY mRNA NPY protein results in increased secretion of Progesterone
|
CTD |
PMID:18070364 PMID:20150881 PMID:22238285 |
|
NCBI chr 4:80,212,111...80,219,310
Ensembl chr 4:80,212,111...80,219,310
|
|
| G
|
Npy1r
|
neuropeptide Y receptor Y1
|
increases expression
|
ISO
|
Progesterone results in increased expression of NPY1R mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr16:27,804,416...27,814,070
Ensembl chr16:27,804,416...27,813,387
|
|
| G
|
Nqo1
|
NAD(P)H quinone dehydrogenase 1
|
multiple interactions increases expression
|
EXP
|
Dicumarol inhibits the reaction [Progesterone results in increased activity of NQO1 protein]; Progesterone results in increased expression of and results in increased activity of NQO1 protein Progesterone results in increased expression of NQO1 mRNA
|
CTD |
PMID:20726854 PMID:21770760 PMID:21947872 |
|
NCBI chr19:52,205,374...52,220,267
Ensembl chr19:52,205,314...52,220,260
|
|
| G
|
Nr0b1
|
nuclear receptor subfamily 0, group B, member 1
|
multiple interactions
|
ISO
|
[[NR0B1 protein binds to STAR promoter] which results in decreased expression of STAR mRNA] which results in decreased abundance of Progesterone; NR0B1 protein inhibits the reaction [[Bucladesine results in increased expression of STAR protein] which results in increased abundance of Progesterone]; NR0B1 protein inhibits the reaction [[Tetradecanoylphorbol Acetate results in increased expression of STAR protein] which results in increased abundance of Progesterone]
|
CTD |
PMID:18787026 |
|
NCBI chr X:50,756,886...50,761,014
Ensembl chr X:54,707,639...54,712,083
|
|
| G
|
Nr1d1
|
nuclear receptor subfamily 1, group D, member 1
|
increases expression
|
EXP
|
Progesterone results in increased expression of NR1D1 mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr10:84,224,599...84,231,812
Ensembl chr10:84,224,540...84,231,812
|
|
| G
|
Nr1d2
|
nuclear receptor subfamily 1, group D, member 2
|
affects expression
|
ISO
|
Progesterone affects the expression of NR1D2 mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr15:9,955,034...9,981,329
Ensembl chr15:9,954,906...9,981,330
|
|
| G
|
Nr1i2
|
nuclear receptor subfamily 1, group I, member 2
|
multiple interactions increases activity
|
ISO EXP
|
[Progesterone co-treated with NR1I2 protein] results in increased expression of UGT1A1 mRNA; Progesterone binds to and results in increased activity of NR1I2 protein Progesterone metabolite results in increased activity of NR1I2 protein Progesterone results in increased activity of NR1I2 protein
|
CTD |
PMID:14613717 PMID:15650019 PMID:15846226 PMID:16054614 PMID:18098064 |
|
NCBI chr11:75,965,717...76,006,733
Ensembl chr11:75,965,632...76,002,380
|
|
| G
|
Nr1i3
|
nuclear receptor subfamily 1, group I, member 3
|
multiple interactions decreases activity
|
ISO
|
Estradiol inhibits the reaction [Progesterone results in decreased activity of NR1I3 protein]; Estrone inhibits the reaction [Progesterone results in decreased activity of NR1I3 protein] [Estradiol co-treated with Progesterone] inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased activity of NR1I3 protein]; [Progesterone co-treated with Estradiol] inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime promotes the reaction [[NR1I3 protein co-treated with FOXO1 protein co-treated with HNF4A protein co-treated with NCOA1 protein] binds to CYP2C9 promoter]]; [Progesterone co-treated with Estradiol] inhibits the reaction [Phenobarbital results in increased activity of NR1I3 protein]; NR1I3 mutant form inhibits the reaction [Progesterone inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in decreased expression of G6PC1 mRNA]]; NR1I3 mutant form inhibits the reaction [Progesterone inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in decreased expression of SREBF1 mRNA]]; NR1I3 mutant form inhibits the reaction [Progesterone inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of CYP2B6 mRNA]]; NR1I3 mutant form inhibits the reaction [Progesterone inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of CYP2C9 mRNA]]; NR1I3 mutant form inhibits the reaction [Progesterone inhibits the reaction [Phenobarbital results in decreased expression of G6PC1 mRNA]]; NR1I3 mutant form inhibits the reaction [Progesterone inhibits the reaction [Phenobarbital results in decreased expression of SREBF1 mRNA]]; NR1I3 mutant form inhibits the reaction [Progesterone inhibits the reaction [Phenobarbital results in increased expression of CYP2B6 mRNA]]; NR1I3 mutant form inhibits the reaction [Progesterone inhibits the reaction [Phenobarbital results in increased expression of CYP2C9 mRNA]]; Progesterone inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime promotes the reaction [[NR1I3 protein co-treated with FOXO1 protein co-treated with HNF4A protein co-treated with NCOA1 protein] binds to CYP2C9 promoter]]; Progesterone inhibits the reaction [Phenobarbital results in increased activity of NR1I3 protein]
|
CTD |
PMID:11075820 PMID:21768169 |
|
NCBI chr13:83,632,940...83,638,193
Ensembl chr13:86,165,349...86,170,370
|
|
| G
|
Nr2c2
|
nuclear receptor subfamily 2, group C, member 2
|
increases expression
|
ISO
|
Progesterone results in increased expression of NR2C2 mRNA
|
CTD |
PMID:21549006 |
|
NCBI chr 4:126,167,350...126,223,942
Ensembl chr 4:126,168,085...126,223,942
|
|
| G
|
Nr3c1
|
nuclear receptor subfamily 3, group C, member 1
|
multiple interactions increases expression affects binding affects expression increases phosphorylation
|
ISO EXP
|
[Hydrocortisone co-treated with Progesterone] results in increased expression of NR3C1 mRNA; [Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with Estradiol] results in decreased expression of NR3C1 protein; [Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in decreased expression of NR3C1 mRNA; NR3C1 protein inhibits the reaction [[Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with Estradiol] results in decreased expression of GRIA1 mRNA]; NR3C1 protein inhibits the reaction [[Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with Estradiol] results in increased expression of ZNF486 mRNA]; NR3C1 protein promotes the reaction [[Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with Estradiol] results in increased expression of WNT4 mRNA]; Progesterone binds to and results in increased activity of NR3C1 protein Progesterone results in increased expression of NR3C1 mRNA NR3C1 protein binds to Progesterone Progesterone affects the expression of NR3C1 mRNA Progesterone binds to NR3C1 protein Progesterone binds to and results in increased activity of NR3C1 protein; Progesterone inhibits the reaction [Ozone results in decreased expression of NR3C1 protein] Progesterone results in increased phosphorylation of NR3C1 protein
|
CTD |
PMID:1597467 PMID:16507850 PMID:17509631 PMID:18060946 PMID:18483179 PMID:19208548 PMID:23275455 PMID:25056680 PMID:28279894 More...
|
|
NCBI chr18:31,522,783...31,644,508
Ensembl chr18:31,522,783...31,643,843
|
|
| G
|
Nr3c2
|
nuclear receptor subfamily 3, group C, member 2
|
affects binding multiple interactions increases activity
|
EXP ISO
|
Progesterone binds to NR3C2 protein [Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with Estradiol] results in increased expression of NR3C2 protein; [Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of NR3C2 mRNA; NR3C2 protein promotes the reaction [[Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with Estradiol] results in decreased expression of GRIA1 mRNA]; NR3C2 protein promotes the reaction [[Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with Estradiol] results in increased expression of DHRS3 mRNA]; NR3C2 protein promotes the reaction [[Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with Estradiol] results in increased expression of FBXO32 mRNA] Progesterone results in increased activity of NR3C2 protein
|
CTD |
PMID:14667981 PMID:15362971 PMID:23275455 |
|
NCBI chr19:47,619,853...47,964,089
Ensembl chr19:47,619,853...47,964,078
|
|
| G
|
Nr4a1
|
nuclear receptor subfamily 4, group A, member 1
|
increases expression multiple interactions
|
ISO
|
Progesterone results in increased expression of NR4A1 mRNA NR4A1 protein mutant form inhibits the reaction [bisphenol A results in increased abundance of Progesterone]; NR4A1 protein promotes the reaction [bisphenol A diglycidyl ether affects the abundance of Progesterone]; NR4A1 protein promotes the reaction [bisphenol A results in increased abundance of Progesterone]
|
CTD |
PMID:12021184 PMID:18037150 PMID:18525235 |
|
NCBI chr 7:134,247,153...134,268,044
Ensembl chr 7:134,247,192...134,268,041
|
|
| G
|
Nr5a1
|
nuclear receptor subfamily 5, group A, member 1
|
multiple interactions increases abundance
|
ISO
|
[NR5A1 protein co-treated with 20-hydroxycholesterol co-treated with Tretinoin co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased abundance of Progesterone; [NR5A1 protein co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased abundance of Progesterone; [NR5A1 protein co-treated with LIF protein co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with Tretinoin] results in increased abundance of Progesterone NR5A1 protein results in increased abundance of Progesterone
|
CTD |
PMID:20045459 PMID:21610156 |
|
NCBI chr 3:22,464,786...22,486,328
Ensembl chr 3:42,875,221...42,896,046
|
|
| G
|
Nr5a2
|
nuclear receptor subfamily 5, group A, member 2
|
decreases abundance increases abundance
|
ISO
|
NR5A2 gene mutant form results in decreased abundance of Progesterone NR5A2 protein results in increased abundance of Progesterone
|
CTD |
PMID:17409375 PMID:18628394 |
|
NCBI chr13:50,865,253...50,985,107
Ensembl chr13:50,867,920...50,984,938
|
|
| G
|
Nrg1
|
neuregulin 1
|
multiple interactions
|
ISO
|
NRG1 protein promotes the reaction [AREG protein results in increased abundance of Progesterone]
|
CTD |
PMID:21047912 |
|
NCBI chr16:65,954,084...67,007,484
Ensembl chr16:65,953,865...66,999,849
|
|
| G
|
Nrp1
|
neuropilin 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of NRP1 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr19:73,256,557...73,411,705
Ensembl chr19:73,256,557...73,411,702
|
|
| G
|
Nrxn3
|
neurexin 3
|
multiple interactions decreases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of NRXN3 mRNA Progesterone results in decreased expression of NRXN3 mRNA
|
CTD |
PMID:20660070 PMID:21540246 |
|
NCBI chr 6:107,641,760...109,272,849
Ensembl chr 6:113,443,524...115,002,540
|
|
| G
|
Nsdhl
|
NAD(P) dependent 3-beta-hydroxysteroid dehydrogenase NSDHL
|
increases expression
|
ISO
|
Progesterone results in increased expression of NSDHL mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr X:155,817,301...155,848,224
Ensembl chr X:155,817,340...155,848,220
|
|
| G
|
Nsg1
|
neuronal vesicle trafficking associated 1
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in increased expression of NSG1 mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr14:76,861,079...76,882,822
Ensembl chr14:76,860,746...76,883,390
|
|
| G
|
Nt5c3b
|
5'-nucleotidase, cytosolic IIIB
|
affects expression
|
ISO
|
Progesterone affects the expression of NT5C3B mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr10:85,358,483...85,376,340
Ensembl chr10:85,862,512...85,875,992
|
|
| G
|
Nt5e
|
5' nucleotidase, ecto
|
increases expression decreases expression
|
EXP ISO
|
Progesterone results in increased expression of NT5E mRNA Progesterone results in decreased expression of NT5E mRNA
|
CTD |
PMID:20726854 PMID:20864642 |
|
NCBI chr 8:89,271,046...89,314,918
Ensembl chr 8:98,150,900...98,195,645
|
|
| G
|
Ntf3
|
neurotrophin 3
|
multiple interactions
|
EXP
|
Progesterone inhibits the reaction [Estradiol results in increased expression of NTF3 protein]
|
CTD |
PMID:15570173 |
|
NCBI chr 4:160,601,161...160,670,623
Ensembl chr 4:160,600,770...160,676,349
|
|
| G
|
Ntm
|
neurotrimin
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of NTM mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr 8:27,376,582...28,366,604
Ensembl chr 8:35,635,640...36,624,807
|
|
| G
|
Ntng1
|
netrin G1
|
increases expression
|
ISO
|
Progesterone results in increased expression of NTNG1 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 2:197,462,785...197,827,681
Ensembl chr 2:200,151,979...200,515,031
|
|
| G
|
Ntrk1
|
neurotrophic receptor tyrosine kinase 1
|
multiple interactions
|
EXP
|
[VIP protein results in increased secretion of Progesterone] which results in decreased expression of NTRK1 mRNA
|
CTD |
PMID:20150881 |
|
NCBI chr 2:175,534,844...175,551,664
Ensembl chr 2:175,534,844...175,551,787
|
|
| G
|
Ntrk3
|
neurotrophic receptor tyrosine kinase 3
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of NTRK3 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 1:141,526,192...141,913,575
Ensembl chr 1:141,542,569...141,913,004
|
|
| G
|
Nts
|
neurotensin
|
multiple interactions
|
ISO
|
Progesterone inhibits the reaction [Estradiol results in increased expression of NTS mRNA]
|
CTD |
PMID:21795739 |
|
NCBI chr 7:39,451,484...39,460,888
Ensembl chr 7:39,451,073...39,460,961
|
|
| G
|
Nudt6
|
nudix hydrolase 6
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of NUDT6 mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr 2:122,218,031...122,234,488
Ensembl chr 2:122,217,861...122,234,344
|
|
| G
|
Nuf2
|
NUF2 component of NDC80 kinetochore complex
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of NUF2 mRNA
|
CTD |
PMID:21795739 |
|
NCBI chr13:84,226,448...84,290,957
Ensembl chr13:84,226,509...84,255,598
|
|
| G
|
Numa1
|
nuclear mitotic apparatus protein 1
|
increases expression
|
ISO
|
Progesterone results in increased expression of NUMA1 mRNA
|
CTD |
PMID:18497975 |
|
NCBI chr 1:156,297,907...156,372,855
Ensembl chr 1:165,709,905...165,784,848
|
|
| G
|
Nup153
|
nucleoporin 153
|
decreases expression
|
EXP
|
Progesterone results in decreased expression of NUP153 mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr17:18,178,434...18,231,109
Ensembl chr17:18,178,456...18,231,109
|
|
| G
|
Nup160
|
nucleoporin 160
|
increases expression
|
ISO
|
Progesterone results in increased expression of NUP160 mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr 3:76,665,786...76,729,296
Ensembl chr 3:97,121,628...97,180,720
|
|
| G
|
Nup54
|
nucleoporin 54
|
increases expression
|
ISO
|
Progesterone results in increased expression of NUP54 mRNA
|
CTD |
PMID:19000923 |
|
NCBI chr14:15,617,630...15,636,029
Ensembl chr14:15,901,991...15,920,334
|
|
| G
|
Nusap1
|
nucleolar and spindle associated protein 1
|
increases expression decreases expression
|
ISO
|
Progesterone results in increased expression of NUSAP1 mRNA Progesterone results in decreased expression of NUSAP1 mRNA
|
CTD |
PMID:18070364 PMID:21795739 |
|
NCBI chr 3:127,057,220...127,092,779
Ensembl chr 3:127,057,265...127,087,237
|
|
| G
|
Oas1a
|
2'-5' oligoadenylate synthetase 1A
|
multiple interactions increases expression
|
ISO
|
TGFB1 protein promotes the reaction [Progesterone results in increased expression of OAS1 mRNA]
|
CTD |
PMID:21768398 |
|
NCBI chr12:41,330,423...41,341,130
Ensembl chr12:41,285,211...41,341,128
|
|
| G
|
Ociad2
|
OCIA domain containing 2
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of OCIAD2 mRNA
|
CTD |
PMID:21540246 |
|
NCBI chr14:35,225,291...35,243,306
Ensembl chr14:35,225,255...35,243,311
|
|
| G
|
Ocln
|
occludin
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of OCLN mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 2:33,391,303...33,442,207
Ensembl chr 2:33,391,303...33,430,411
|
|
| G
|
Odc1
|
ornithine decarboxylase 1
|
decreases expression increases expression
|
ISO EXP
|
Progesterone results in decreased expression of ODC1 mRNA Progesterone results in increased expression of ODC1 mRNA
|
CTD |
PMID:18037150 PMID:21770760 |
|
NCBI chr 6:46,058,439...46,065,148
Ensembl chr 6:46,058,463...46,065,146
|
|
| G
|
Ogfod1
|
2-oxoglutarate and iron-dependent oxygenase domain containing 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of OGFOD1 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr19:10,945,031...10,974,602
Ensembl chr19:10,950,060...10,980,519
|
|
| G
|
Ogt
|
O-linked N-acetylglucosamine (GlcNAc) transferase
|
decreases expression increases expression
|
ISO
|
Progesterone results in decreased expression of OGT mRNA Progesterone results in increased expression of OGT mRNA
|
CTD |
PMID:18037150 PMID:18070364 |
|
NCBI chr X:70,811,317...70,856,123
Ensembl chr X:70,811,319...70,856,123
|
|
| G
|
Olah
|
oleoyl-ACP hydrolase
|
increases expression
|
ISO
|
Progesterone results in increased expression of OLAH mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr17:79,786,441...79,811,692
Ensembl chr17:79,786,832...79,811,688
|
|
| G
|
Olfm1
|
olfactomedin 1
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of OLFM1 mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr 3:31,918,512...31,956,261
Ensembl chr 3:31,918,573...31,956,260
|
|
| G
|
Olfml1
|
olfactomedin-like 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of OLFML1 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 1:161,478,129...161,502,541
Ensembl chr 1:170,889,980...170,915,762
|
|
| G
|
Olfml2b
|
olfactomedin-like 2B
|
increases expression
|
ISO
|
Progesterone results in increased expression of OLFML2B mRNA
|
CTD |
PMID:20864642 |
|
NCBI chr13:85,402,151...85,439,342
Ensembl chr13:85,402,169...85,439,342
|
|
| G
|
Olfml3
|
olfactomedin-like 3
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of OLFML3 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 2:191,244,221...191,247,050
Ensembl chr 2:193,932,665...193,935,494
|
|
| G
|
Olr1
|
oxidized low density lipoprotein receptor 1
|
decreases expression
|
EXP
|
Progesterone results in decreased expression of OLR1 mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr 4:162,926,436...162,949,057
Ensembl chr 4:164,612,463...164,634,598
|
|
| G
|
Omd
|
osteomodulin
|
increases expression
|
ISO EXP
|
Progesterone results in increased expression of OMD mRNA
|
CTD |
PMID:20726854 PMID:20864642 PMID:21795739 |
|
NCBI chr17:15,266,646...15,274,870
Ensembl chr17:15,266,646...15,274,870
|
|
| G
|
Oplah
|
5-oxoprolinase (ATP-hydrolysing)
|
increases expression
|
EXP
|
Progesterone results in increased expression of OPLAH mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr 7:109,892,136...109,932,403
Ensembl chr 7:109,891,405...109,915,979
|
|
| G
|
Opn3
|
opsin 3
|
increases expression
|
ISO
|
Progesterone results in increased expression of OPN3 mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr13:87,589,333...87,619,847
Ensembl chr13:90,121,560...90,152,076
|
|
| G
|
Oprk1
|
opioid receptor, kappa 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of OPRK1 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 5:13,860,016...13,877,823
Ensembl chr 5:18,657,871...18,675,671
|
|
| G
|
Orai2
|
ORAI calcium release-activated calcium modulator 2
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of ORAI2 mRNA
|
CTD |
PMID:21540246 |
|
NCBI chr12:26,136,922...26,157,041
Ensembl chr12:26,132,193...26,157,041
|
|
| G
|
Orc2
|
origin recognition complex, subunit 2
|
increases expression
|
ISO
|
Progesterone results in increased expression of ORC2 mRNA
|
CTD |
PMID:18497975 |
|
NCBI chr 9:60,001,631...60,038,301
Ensembl chr 9:67,496,825...67,526,649
|
|
| G
|
Orc4
|
origin recognition complex, subunit 4
|
increases expression
|
ISO
|
Progesterone results in increased expression of ORC4 mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr 3:33,290,844...33,334,022
Ensembl chr 3:53,703,615...53,742,264
|
|
| G
|
Orm1
|
orosomucoid 1
|
multiple interactions increases expression affects expression decreases expression affects binding
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of ORM1 mRNA; Progesterone inhibits the reaction [Warfarin binds to ORM1 protein alternative form] Progesterone results in increased expression of ORM1 mRNA Progesterone affects the expression of ORM1 mRNA Progesterone results in decreased expression of ORM1 mRNA Progesterone binds to ORM1 protein; Progesterone binds to ORM1 protein alternative form
|
CTD |
PMID:8946472 PMID:16901474 PMID:17251523 PMID:17404688 PMID:19000923 |
|
NCBI chr 5:76,766,637...76,776,149
Ensembl chr 5:81,788,395...81,791,667
|
|
| G
|
Osbpl11
|
oxysterol binding protein-like 11
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of OSBPL11 mRNA; [Progesterone co-treated with Estradiol] results in increased expression of OSBPL11 mRNA
|
CTD |
PMID:17404688 PMID:20660070 |
|
NCBI chr11:67,533,669...67,616,795
Ensembl chr11:81,038,985...81,101,299
|
|
| G
|
Osr1
|
odd-skipped related transcription factor 1
|
increases expression
|
ISO
|
Progesterone results in increased expression of OSR1 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 6:38,088,688...38,100,010
Ensembl chr 6:38,093,011...38,100,021
|
|
| G
|
Osr2
|
odd-skipped related transcription factor 2
|
increases expression multiple interactions
|
ISO
|
Progesterone results in increased expression of OSR2 mRNA Progesterone inhibits the reaction [Estradiol results in increased expression of OSR2 mRNA]
|
CTD |
PMID:20864642 PMID:21795739 |
|
NCBI chr 7:66,487,841...66,495,003
Ensembl chr 7:68,373,049...68,380,805
|
|
| G
|
Otub1
|
OTU deubiquitinase, ubiquitin aldehyde binding 1
|
affects expression
|
ISO
|
Progesterone affects the expression of OTUB1 mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr 1:213,816,400...213,824,679
Ensembl chr 1:213,816,400...213,824,679
|
|
| G
|
Otulinl
|
OTU deubiquitinase with linear linkage specificity like
|
multiple interactions increases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of OTULINL mRNA Progesterone results in increased expression of OTULINL mRNA
|
CTD |
PMID:18070364 PMID:20660070 PMID:21795739 |
|
NCBI chr 2:80,136,411...80,164,290
Ensembl chr 2:80,139,262...80,166,962
|
|
| G
|
Ovol1
|
ovo like transcriptional repressor 1
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of OVOL1 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 1:212,284,601...212,296,106
Ensembl chr 1:212,284,605...212,296,106
|
|
| G
|
Oxt
|
oxytocin/neurophysin I prepropeptide
|
multiple interactions
|
EXP ISO
|
Progesterone inhibits the reaction [Estradiol results in increased expression of OXT mRNA] [Estradiol co-treated with Progesterone] results in increased expression of OXT mRNA; ESR2 affects the reaction [[Estradiol co-treated with Progesterone] results in increased expression of OXT mRNA]
|
CTD |
PMID:12834440 PMID:17400809 |
|
NCBI chr 3:138,235,754...138,236,594
Ensembl chr 3:138,235,754...138,236,594
|
|
| G
|
Oxtr
|
oxytocin receptor
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of OXTR mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr 4:147,154,374...147,171,723
Ensembl chr 4:147,154,374...147,170,750
|
|
| G
|
P2rx3
|
purinergic receptor P2X 3
|
multiple interactions decreases activity
|
EXP
|
Mifepristone inhibits the reaction [Progesterone results in decreased activity of P2RX3 protein]
|
CTD |
PMID:21178388 |
|
NCBI chr 3:90,487,506...90,531,315
Ensembl chr 3:90,487,506...90,531,794
|
|
| G
|
P2ry14
|
purinergic receptor P2Y14
|
multiple interactions increases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of P2RY14 mRNA; [Progesterone co-treated with Estradiol] results in increased expression of P2RY14 mRNA Progesterone inhibits the reaction [Estradiol results in increased expression of P2RY14 mRNA] Progesterone results in increased expression of P2RY14 mRNA
|
CTD |
PMID:17404688 PMID:18367319 PMID:20660070 PMID:20864642 |
|
NCBI chr 2:143,372,697...143,413,213
Ensembl chr 2:145,516,390...145,564,788
|
|
| G
|
P3h2
|
prolyl 3-hydroxylase 2
|
increases expression multiple interactions
|
ISO
|
Progesterone results in increased expression of P3H2 mRNA [Estradiol co-treated with Progesterone] results in increased expression of P3H2 mRNA
|
CTD |
PMID:20660070 PMID:21540246 |
|
NCBI chr11:88,139,086...88,280,221
Ensembl chr11:88,139,078...88,281,203
|
|
| G
|
P4ha2
|
prolyl 4-hydroxylase subunit alpha 2
|
affects expression
|
ISO
|
Progesterone affects the expression of P4HA2 mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr10:38,743,894...38,772,741
Ensembl chr10:38,743,894...38,772,993
|
|
| G
|
Padi2
|
peptidyl arginine deiminase 2
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of PADI2 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 5:158,492,087...158,534,662
Ensembl chr 5:158,492,066...158,534,662
|
|
| G
|
Paep
|
progestagen associated endometrial protein
|
multiple interactions increases metabolic processing increases abundance
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of PAEP mRNA; [Estradiol co-treated with Progesterone] results in increased expression of PAEP mRNA PAEP protein modified form results in increased metabolism of Progesterone PAEP protein modified form results in increased abundance of Progesterone; PAEP protein results in increased abundance of Progesterone
|
CTD |
PMID:15852231 PMID:17649829 PMID:20660070 PMID:23029392 |
|
NCBI chr 3:8,531,136...8,534,430
|
|
| G
|
Pag1
|
phosphoprotein membrane anchor with glycosphingolipid microdomains 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of PAG1 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 2:93,842,747...93,984,314
Ensembl chr 2:93,964,594...93,977,227
|
|
| G
|
Pak1ip1
|
PAK1 interacting protein 1
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of PAK1IP1 mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr17:23,742,217...23,753,325
Ensembl chr17:23,939,509...23,959,055
|
|
| G
|
Palmd
|
palmdelphin
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of PALMD mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 2:204,889,526...204,941,355
Ensembl chr 2:207,574,249...207,626,239
|
|
| G
|
Pappa
|
pappalysin
|
multiple interactions increases expression decreases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of PAPPA mRNA; PAPPA protein affects the reaction [CGB3 protein results in increased abundance of Progesterone] Progesterone results in increased expression of PAPPA mRNA Progesterone results in decreased expression of PAPPA mRNA
|
CTD |
PMID:18497975 PMID:20130263 PMID:20660070 PMID:21273126 PMID:21795739 |
|
NCBI chr 5:83,513,358...83,751,364
Ensembl chr 5:83,513,358...83,751,361
|
|
| G
|
Papss2
|
3'-phosphoadenosine 5'-phosphosulfate synthase 2
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of PAPSS2 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 1:239,867,597...239,952,614
Ensembl chr 1:239,867,574...239,952,616
|
|
| G
|
Parm1
|
prostate androgen-regulated mucin-like protein 1
|
increases expression
|
EXP
|
Progesterone results in increased expression of PARM1 mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr14:16,752,541...16,861,570
Ensembl chr14:16,752,541...16,881,138
|
|
| G
|
Patz1
|
POZ (BTB) and AT hook containing zinc finger 1
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of PATZ1 mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr14:82,378,226...82,396,679
Ensembl chr14:82,377,697...82,396,686
|
|
| G
|
Pax5
|
paired box 5
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in increased expression of PAX5 mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr 5:63,554,784...63,741,380
Ensembl chr 5:63,560,722...63,739,987
|
|
| G
|
Pbk
|
PDZ binding kinase
|
increases expression decreases expression
|
ISO
|
Progesterone results in increased expression of PBK mRNA Progesterone results in decreased expression of PBK mRNA
|
CTD |
PMID:18070364 PMID:21795739 |
|
NCBI chr15:44,198,506...44,209,572
Ensembl chr15:44,198,544...44,209,570
|
|
| G
|
Pbx1
|
PBX homeobox 1
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of PBX1 mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr13:80,278,766...80,588,563
Ensembl chr13:82,812,131...83,121,066
|
|
| G
|
Pcbp3
|
poly(rC) binding protein 3
|
increases expression
|
ISO
|
Progesterone results in increased expression of PCBP3 mRNA
|
CTD |
PMID:20864642 |
|
NCBI chr20:11,635,579...11,877,721
Ensembl chr20:11,677,751...11,877,722
|
|
| G
|
Pcca
|
propionyl-CoA carboxylase subunit alpha
|
decreases expression increases expression
|
ISO EXP
|
Progesterone results in decreased expression of PCCA mRNA Progesterone results in increased expression of PCCA mRNA
|
CTD |
PMID:20726854 PMID:21540246 |
|
NCBI chr15:106,034,586...106,374,908
Ensembl chr15:106,034,610...106,374,908
|
|
| G
|
Pcdh18
|
protocadherin 18
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of PCDH18 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 2:135,982,929...135,996,917
Ensembl chr 2:135,983,144...135,996,826
|
|
| G
|
Pcdh7
|
protocadherin 7
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of PCDH7 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr14:56,684,817...57,114,976
Ensembl chr14:56,687,725...57,112,665
|
|
| G
|
Pcdh9
|
protocadherin 9
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of PCDH9 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr15:69,340,108...70,237,531
Ensembl chr15:75,749,278...76,645,302
|
|
| G
|
Pcdhga1
|
protocadherin gamma subfamily A, 1
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of PCDHGA1 mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr18:29,487,404...29,667,865
|
|
| G
|
Pcdhga11
|
protocadherin gamma subfamily A, 11
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of PCDHGA11 mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr18:29,583,373...29,667,865
|
|
| G
|
Pcdhga3
|
protocadherin gamma subfamily A, 3
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of PCDHGA3 mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr18:29,499,148...29,667,865
|
|
| G
|
Pcdhgc3
|
protocadherin gamma subfamily C, 3
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of PCDHGC3 mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr18:29,633,016...29,667,865
|
|
| G
|
Pcgf2
|
polycomb group ring finger 2
|
affects expression
|
ISO
|
Progesterone affects the expression of PCGF2 mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr10:82,682,563...82,694,563
Ensembl chr10:83,179,916...83,183,999
|
|
| G
|
Pck1
|
phosphoenolpyruvate carboxykinase 1
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in decreased expression of PCK1 mRNA]; [Progesterone co-treated with Estradiol] inhibits the reaction [Phenobarbital results in decreased expression of PCK1 mRNA]; Progesterone inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime inhibits the reaction [HNF4A protein binds to PCK1 promoter]]; Progesterone inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in decreased expression of PCK1 mRNA]; Progesterone inhibits the reaction [Phenobarbital results in decreased expression of PCK1 mRNA]; Progesterone promotes the reaction [Estradiol inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime inhibits the reaction [HNF4A protein binds to PCK1 promoter]]] 1,4-bis(2-(3,5-dichloropyridyloxy))benzene inhibits the reaction [[Progesterone co-treated with Estradiol] results in increased expression of PCK1 mRNA]; [Progesterone co-treated with Estradiol] results in increased expression of PCK1 mRNA
|
CTD |
PMID:21768169 |
|
NCBI chr 3:182,348,572...182,354,521
Ensembl chr 3:182,348,572...182,354,561
|
|
| G
|
Pck2
|
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
|
increases expression
|
ISO
|
Progesterone results in increased expression of PCK2 mRNA
|
CTD |
PMID:21795739 |
|
NCBI chr15:32,997,853...33,006,691
Ensembl chr15:32,997,834...33,016,864
|
|
| G
|
Pclaf
|
PCNA clamp associated factor
|
increases expression decreases expression
|
ISO
|
Progesterone results in increased expression of PCLAF mRNA Progesterone results in decreased expression of PCLAF mRNA
|
CTD |
PMID:18070364 PMID:21795739 |
|
NCBI chr 8:75,311,028...75,328,108
Ensembl chr 8:75,315,707...75,328,106
|
|
| G
|
Pcna
|
proliferating cell nuclear antigen
|
multiple interactions decreases expression increases expression
|
ISO EXP
|
Estradiol promotes the reaction [Progesterone inhibits the reaction [perfluorooctanoic acid results in decreased expression of PCNA protein]]; Lithium Chloride inhibits the reaction [Progesterone inhibits the reaction [Estradiol results in increased expression of PCNA protein]]; Progesterone inhibits the reaction [Estradiol results in increased expression of PCNA protein]; Progesterone inhibits the reaction [perfluorooctanoic acid results in decreased expression of PCNA protein]; Progesterone promotes the reaction [Estradiol inhibits the reaction [perfluorooctanoic acid results in decreased expression of PCNA protein]] [Progesterone co-treated with Estrogens] results in increased expression of PCNA protein Progesterone results in decreased expression of PCNA mRNA Progesterone results in increased expression of PCNA mRNA
|
CTD |
PMID:15845746 PMID:16966611 PMID:19847363 PMID:20726854 PMID:21258428 PMID:22414604 More...
|
|
NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:139,951,941...139,955,901
|
|
| G
|
Pcsk5
|
proprotein convertase subtilisin/kexin type 5
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of PCSK5 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 1:224,263,823...224,694,350
Ensembl chr 1:224,264,678...224,694,347
|
|
| G
|
Pcsk6
|
proprotein convertase subtilisin/kexin type 6
|
multiple interactions increases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of PCSK6 mRNA; [Progesterone co-treated with Estradiol] results in increased expression of PCSK6 mRNA Progesterone results in increased expression of PCSK6 mRNA
|
CTD |
PMID:17404688 PMID:18070364 PMID:20660070 |
|
NCBI chr 1:119,428,978...119,627,626
Ensembl chr 1:128,839,232...129,052,128
|
|
| G
|
Pdap1
|
PDGFA associated protein 1
|
increases expression
|
ISO
|
Progesterone results in increased expression of PDAP1 mRNA
|
CTD |
PMID:16888808 |
|
NCBI chr12:14,584,414...14,594,641
Ensembl chr12:14,584,398...14,594,641
|
|
| G
|
Pdcd4
|
programmed cell death 4
|
increases expression
|
ISO
|
Progesterone results in increased expression of PDCD4 mRNA
|
CTD |
PMID:18497975 |
|
NCBI chr 1:262,912,659...262,949,581
Ensembl chr 1:262,926,656...262,950,189
|
|
| G
|
Pdcl3
|
phosducin-like 3
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of PDCL3 mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr 9:48,730,083...48,738,554
Ensembl chr 9:48,723,767...48,739,529
|
|
| G
|
Pde1c
|
phosphodiesterase 1C
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of PDE1C mRNA
|
CTD |
PMID:21795739 |
|
NCBI chr 4:85,300,858...85,777,948
Ensembl chr 4:86,626,282...87,193,259
|
|
| G
|
Pde4b
|
phosphodiesterase 4B
|
decreases expression increases expression
|
ISO
|
Progesterone results in decreased expression of PDE4B mRNA Progesterone results in increased expression of PDE4B mRNA
|
CTD |
PMID:18497975 PMID:21795739 |
|
NCBI chr 5:122,028,956...122,598,267
Ensembl chr 5:122,135,174...122,598,267
|
|
| G
|
Pde4dip
|
phosphodiesterase 4D interacting protein
|
increases expression
|
EXP
|
Progesterone results in increased expression of PDE4DIP mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr 2:187,982,002...188,178,937
Ensembl chr 2:187,981,878...188,178,869
|
|
| G
|
Pde9a
|
phosphodiesterase 9A
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of PDE9A mRNA
|
CTD |
PMID:21540246 |
|
NCBI chr20:9,471,136...9,564,286
Ensembl chr20:9,471,167...9,564,286
|
|
| G
|
Pdgfa
|
platelet derived growth factor subunit A
|
multiple interactions increases expression
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of PDGFA mRNA Progesterone results in increased expression of PDGFA mRNA
|
CTD |
PMID:16888808 PMID:17404688 |
|
NCBI chr12:15,645,549...15,667,056
Ensembl chr12:20,754,208...20,780,322
|
|
| G
|
Pdgfb
|
platelet derived growth factor subunit B
|
multiple interactions decreases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of PDGFB mRNA; [Progesterone co-treated with Estradiol] results in decreased expression of PDGFB mRNA Progesterone results in decreased expression of PDGFB mRNA
|
CTD |
PMID:17404688 PMID:20660070 |
|
NCBI chr 7:113,419,882...113,438,343
Ensembl chr 7:113,420,710...113,438,343
|
|
| G
|
Pdgfra
|
platelet derived growth factor receptor alpha
|
multiple interactions increases expression
|
ISO
|
[Progesterone results in increased secretion of [VEGFA protein binds to VEGFA protein]] which results in increased phosphorylation of PDGFRA protein; Progesterone promotes the reaction [Imatinib Mesylate results in decreased expression of PDGFRA protein modified form]; Progesterone promotes the reaction [Imatinib Mesylate results in decreased expression of PDGFRA protein] Progesterone results in increased expression of PDGFRA mRNA [Estradiol co-treated with Progesterone co-treated with Cuprizone] results in increased expression of PDGFRA mRNA
|
CTD |
PMID:16888808 PMID:17614352 PMID:19031445 PMID:22238285 |
|
NCBI chr14:33,360,027...33,408,604
Ensembl chr14:33,360,028...33,408,516
|
|
| G
|
Pdgfrb
|
platelet derived growth factor receptor beta
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in increased expression of PDGFRB mRNA
|
CTD |
PMID:18692832 |
|
NCBI chr18:56,770,348...56,809,228
Ensembl chr18:56,770,348...56,809,233
|
|
| G
|
Pdia3
|
protein disulfide isomerase family A, member 3
|
affects expression
|
ISO
|
Progesterone affects the expression of PDIA3 mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr 3:128,841,781...128,865,733
Ensembl chr 3:128,841,917...128,867,327
|
|
| G
|
Pdia4
|
protein disulfide isomerase family A, member 4
|
affects expression
|
ISO
|
Progesterone affects the expression of PDIA4 mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr 4:76,803,198...76,822,245
Ensembl chr 4:78,134,144...78,153,191
|
|
| G
|
Pdia6
|
protein disulfide isomerase family A, member 6
|
affects expression
|
ISO
|
Progesterone affects the expression of PDIA6 mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr 6:45,791,704...45,808,947
Ensembl chr 6:45,791,678...45,810,091
|
|
| G
|
Pdk2
|
pyruvate dehydrogenase kinase 2
|
increases expression
|
EXP
|
Progesterone results in increased expression of PDK2 mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr10:80,469,388...80,483,988
Ensembl chr10:80,469,389...80,484,355
|
|
| G
|
Pdlim1
|
PDZ and LIM domain 1
|
decreases expression increases expression
|
ISO
|
Progesterone results in decreased expression of PDLIM1 mRNA Progesterone results in increased expression of PDLIM1 mRNA
|
CTD |
PMID:18070364 PMID:21795739 |
|
NCBI chr 1:248,991,818...249,040,409
Ensembl chr 1:248,991,818...249,047,379
|
|
| G
|
Pdlim3
|
PDZ and LIM domain 3
|
increases expression
|
ISO
|
Progesterone results in increased expression of PDLIM3 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr16:46,352,460...46,383,680
Ensembl chr16:53,085,020...53,116,217
|
|
| G
|
Pdlim7
|
PDZ and LIM domain 7
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of PDLIM7 mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr17:9,129,603...9,144,956
Ensembl chr17:9,129,525...9,144,956
|
|
| G
|
Pdp1
|
pyruvate dehydrogenase phosphatase catalytic subunit 1
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of PDP1 mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr 5:30,245,699...30,252,494
Ensembl chr 5:30,242,704...30,253,960
|
|
| G
|
Pdpk1
|
3-phosphoinositide dependent protein kinase-1
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of PDPK1 mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr10:13,105,435...13,182,664
Ensembl chr10:13,610,063...13,679,181
|
|
| G
|
Pdpn
|
podoplanin
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of PDPN mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 5:160,884,995...160,919,112
Ensembl chr 5:160,884,993...160,925,637
|
|
| G
|
Pds5a
|
PDS5 cohesin associated factor A
|
increases expression
|
ISO
|
Progesterone results in increased expression of PDS5A mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr14:42,551,653...42,651,074
Ensembl chr14:42,905,328...43,004,740
|
|
| G
|
Pdzd2
|
PDZ domain containing 2
|
multiple interactions increases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of PDZD2 mRNA; [Progesterone co-treated with Estradiol] results in increased expression of PDZD2 mRNA Progesterone results in increased expression of PDZD2 mRNA
|
CTD |
PMID:17404688 PMID:20660070 |
|
NCBI chr 2:61,384,614...61,770,516
Ensembl chr 2:63,111,650...63,497,478
|
|
| G
|
Pecam1
|
platelet and endothelial cell adhesion molecule 1
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of PECAM1 mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr10:91,590,521...91,652,279
Ensembl chr10:92,090,235...92,151,839
|
|
| G
|
Peg10
|
paternally expressed 10
|
decreases expression increases expression
|
ISO
|
Progesterone results in decreased expression of PEG10 mRNA Progesterone results in increased expression of PEG10 mRNA
|
CTD |
PMID:18070364 PMID:21795739 |
|
NCBI chr 4:32,842,441...32,855,639
Ensembl chr 4:33,817,190...33,819,166 Ensembl chr 4:33,817,190...33,819,166
|
|
| G
|
Pelo
|
pelota mRNA surveillance and ribosome rescue factor
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of PELO mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 2:46,797,853...46,799,621
Ensembl chr 2:48,530,907...48,532,761
|
|
| G
|
Pemt
|
phosphatidylethanolamine N-methyltransferase
|
multiple interactions increases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of PEMT mRNA Progesterone results in increased expression of PEMT mRNA
|
CTD |
PMID:20660070 PMID:20864642 |
|
NCBI chr10:45,275,434...45,349,651
Ensembl chr10:45,275,412...45,420,037
|
|
| G
|
Penk
|
proenkephalin
|
affects expression multiple interactions
|
ISO
|
Progesterone affects the expression of PENK mRNA [Estradiol co-treated with Progesterone] results in decreased expression of PENK mRNA
|
CTD |
PMID:17251523 PMID:19693291 |
|
NCBI chr 5:21,981,381...21,987,074
Ensembl chr 5:21,981,382...21,986,705
|
|
| G
|
Per1
|
period circadian regulator 1
|
increases expression multiple interactions
|
EXP ISO
|
Progesterone results in increased expression of PER1 mRNA; Progesterone results in increased expression of PER1 protein Mifepristone inhibits the reaction [Progesterone results in increased expression of PER1 mRNA]
|
CTD |
PMID:17761890 PMID:18037150 PMID:20096720 PMID:21795739 |
|
NCBI chr10:54,299,002...54,313,804
Ensembl chr10:54,302,641...54,314,211
|
|
| G
|
Per2
|
period circadian regulator 2
|
decreases expression multiple interactions increases expression
|
EXP ISO
|
Progesterone results in decreased expression of PER2 mRNA [Progesterone co-treated with Estradiol] results in increased expression of PER2 mRNA Progesterone results in increased expression of PER2 mRNA
|
CTD |
PMID:20096720 PMID:20726854 |
|
NCBI chr 9:99,454,828...99,497,069
Ensembl chr 9:99,454,830...99,496,993
|
|
| G
|
Per3
|
period circadian regulator 3
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of PER3 mRNA
|
CTD |
PMID:21795739 |
|
NCBI chr 5:166,740,914...166,778,243
Ensembl chr 5:166,743,050...166,777,999
|
|
| G
|
Pfas
|
phosphoribosylformylglycinamidine synthase
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of PFAS mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr10:54,189,157...54,210,685
Ensembl chr10:54,189,157...54,207,272
|
|
| G
|
Pfkm
|
phosphofructokinase, muscle
|
increases expression
|
EXP
|
Progesterone results in increased expression of PFKM mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr 7:129,221,679...129,259,192
Ensembl chr 7:131,100,753...131,138,248
|
|
| G
|
Pfn2
|
profilin 2
|
decreases expression
|
EXP
|
Progesterone results in decreased expression of PFN2 mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr 2:142,067,102...142,072,938
Ensembl chr 2:144,205,636...144,222,936
|
|
| G
|
Pgap1
|
post-GPI attachment to proteins inositol deacylase 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of PGAP1 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 9:55,975,574...56,044,325
Ensembl chr 9:63,470,024...63,538,772
|
|
| G
|
Pgbd5
|
piggyBac transposable element derived 5
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in increased expression of PGBD5 mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr19:69,234,171...69,299,315
Ensembl chr19:69,234,171...69,299,560
|
|
| G
|
Pglyrp1
|
peptidoglycan recognition protein 1
|
affects expression increases expression
|
ISO
|
Progesterone affects the expression of PGLYRP1 mRNA Progesterone results in increased expression of PGLYRP1 mRNA
|
CTD |
PMID:17251523 PMID:21549006 |
|
NCBI chr 1:78,531,815...78,537,001
Ensembl chr 1:87,651,271...87,665,048
|
|
| G
|
Pgm2l1
|
phosphoglucomutase 2-like 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of PGM2L1 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 1:154,571,410...154,620,901
Ensembl chr 1:163,983,917...164,033,027
|
|
| G
|
Pgm3
|
phosphoglucomutase 3
|
increases expression
|
ISO
|
Progesterone results in increased expression of PGM3 mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr 8:96,398,331...96,416,045
Ensembl chr 8:96,398,269...96,416,021
|
|
| G
|
Pgr
|
progesterone receptor
|
multiple interactions increases activity increases expression affects expression affects localization decreases expression affects binding
|
ISO EXP
|
1-hydroxypyrene inhibits the reaction [Progesterone binds to PGR protein]; 2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene inhibits the reaction [Progesterone binds to PGR protein]; 2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene inhibits the reaction [Progesterone results in increased expression of PGR protein]; 4-hydroxy-2',3',4'-5'-tetrachlorobiphenyl inhibits the reaction [Progesterone binds to PGR protein]; 4-hydroxy-2',4',6'-trichlorobiphenyl inhibits the reaction [Progesterone binds to PGR protein]; 6-hydroxychrysene inhibits the reaction [Progesterone binds to PGR protein]; [8-Bromo Cyclic Adenosine Monophosphate co-treated with Progesterone co-treated with Estradiol] affects the expression of and affects the phosphorylation of PGR protein; [Progesterone affects the activity of PGR protein alternative form] which affects the expression of AREG mRNA; [Progesterone affects the activity of PGR protein alternative form] which affects the expression of IGFBP3 mRNA; [Progesterone affects the activity of PGR protein alternative form] which affects the expression of ITGB4 mRNA; [Progesterone affects the activity of PGR protein alternative form] which affects the expression of MT1L mRNA; [Progesterone co-treated with 1-hydroxypyrene] results in decreased expression of PGR mRNA; [Progesterone co-treated with 4-hydroxy-2',3',4'-5'-tetrachlorobiphenyl] results in decreased expression of PGR mRNA; [Progesterone co-treated with 4-hydroxy-2',4',6'-trichlorobiphenyl] results in decreased expression of PGR mRNA; [Progesterone co-treated with 6-hydroxychrysene] results in decreased expression of PGR mRNA; [Progesterone co-treated with Endosulfan] results in decreased expression of PGR mRNA; [Progesterone co-treated with Hexachlorocyclohexane] results in decreased expression of PGR mRNA; alachlor inhibits the reaction [Progesterone binds to PGR protein]; Aldicarb inhibits the reaction [Progesterone results in increased activity of PGR protein]; Aldrin inhibits the reaction [Progesterone binds to PGR protein]; Apigenin inhibits the reaction [Progesterone binds to PGR protein]; bendiocarb inhibits the reaction [Progesterone results in increased activity of PGR protein]; biochanin A inhibits the reaction [Progesterone binds to PGR protein]; bisphenol A inhibits the reaction [Progesterone binds to PGR protein]; bisphenol AF inhibits the reaction [Progesterone binds to PGR protein]; bisphenol B inhibits the reaction [Progesterone binds to PGR protein]; bisphenol Z inhibits the reaction [Progesterone binds to PGR protein]; Butylated Hydroxyanisole inhibits the reaction [Progesterone binds to PGR protein]; Carbaryl inhibits the reaction [Progesterone results in increased activity of PGR protein]; Chlordecone inhibits the reaction [Progesterone binds to PGR protein]; Chlorpyrifos inhibits the reaction [Progesterone binds to PGR protein]; Chlorpyrifos metabolite inhibits the reaction [Progesterone binds to PGR protein]; Coal Ash inhibits the reaction [Progesterone results in increased activity of PGR protein]; DDT inhibits the reaction [Progesterone binds to PGR protein]; DDT inhibits the reaction [Progesterone results in increased expression of PGR protein]; Dichlorodiphenyl Dichloroethylene inhibits the reaction [Progesterone binds to PGR protein]; Dichlorodiphenyl Dichloroethylene inhibits the reaction [Progesterone results in increased expression of PGR protein]; Endosulfan inhibits the reaction [Progesterone binds to PGR protein]; Endosulfan inhibits the reaction [Progesterone results in increased expression of PGR protein]; Estradiol promotes the reaction [Progesterone binds to PGR protein]; fenvalerate inhibits the reaction [Progesterone results in increased expression of PGR protein]; Hexachlorocyclohexane inhibits the reaction [Progesterone binds to PGR protein]; Industrial Waste inhibits the reaction [Progesterone results in increased expression of PGR protein]; kaempferol inhibits the reaction [Progesterone binds to PGR protein]; Methomyl inhibits the reaction [Progesterone results in increased activity of PGR protein]; Methoxychlor inhibits the reaction [Progesterone binds to PGR protein]; Mifepristone inhibits the reaction [Progesterone results in increased expression of PGR protein]; Mifepristone promotes the reaction [Progesterone affects the expression of PGR mRNA]; Mitotane inhibits the reaction [Progesterone binds to PGR protein]; nonachlor inhibits the reaction [Progesterone binds to PGR protein]; nonylphenol inhibits the reaction [Progesterone binds to PGR protein]; nonylphenol inhibits the reaction [Progesterone results in increased expression of PGR protein]; O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate inhibits the reaction [Progesterone binds to PGR protein]; o,p'-DDT inhibits the reaction [Progesterone binds to PGR protein]; o,p'-DDT inhibits the reaction [Progesterone results in increased expression of PGR protein]; oxamyl inhibits the reaction [Progesterone results in increased activity of PGR protein]; Particulate Matter inhibits the reaction [Progesterone results in increased activity of PGR protein]; Permethrin inhibits the reaction [Progesterone results in increased expression of PGR protein]; Pesticides inhibits the reaction [Progesterone results in increased expression of PGR mRNA]; PGR protein affects the reaction [[Estradiol co-treated with Progesterone] results in increased expression of ITGA1]; PGR protein affects the reaction [Progesterone results in increased expression of TRIM22 mRNA]; phthalic acid analog inhibits the reaction [Progesterone binds to PGR protein]; Progesterone binds to and results in increased activity of PGR protein; Progesterone inhibits the reaction [Estradiol results in increased expression of PGR mRNA]; Progesterone promotes the reaction [PGR protein results in increased expression of CXCL14 mRNA]; Propoxur inhibits the reaction [Progesterone results in increased activity of PGR protein]; Resveratrol inhibits the reaction [PGR protein affects the reaction [[Estradiol co-treated with Progesterone] results in increased expression of ITGA1]]; Soil Pollutants inhibits the reaction [Progesterone results in increased expression of PGR mRNA]; Soot inhibits the reaction [Progesterone results in increased activity of PGR protein]; Toxaphene inhibits the reaction [Progesterone binds to PGR protein]; Vehicle Emissions inhibits the reaction [Progesterone results in increased activity of PGR protein]; vinclozolin inhibits the reaction [Progesterone binds to PGR protein]; vinclozolin inhibits the reaction [Progesterone results in increased expression of PGR protein]; zearalenol promotes the reaction [Progesterone binds to and results in increased activity of PGR protein]; Zearalenone inhibits the reaction [Progesterone binds to and results in increased activity of PGR protein]; ZNF366 protein inhibits the reaction [Progesterone results in increased activity of PGR protein] Progesterone results in increased expression of PGR mRNA; Progesterone results in increased expression of PGR protein; Progesterone results in increased expression of PGR protein alternative form [Estradiol co-treated with Progesterone] affects the expression of PGR protein; [lipopolysaccharide, E coli O55-B5 co-treated with Progesterone] results in decreased expression of PGR protein alternative form; [Progesterone results in increased activity of PGR protein] which results in decreased expression of RBP4 mRNA; [Progesterone results in increased activity of PGR protein] which results in increased expression of ADH5 mRNA; [Progesterone results in increased activity of PGR protein] which results in increased expression of ALDH1A1 mRNA; [Progesterone results in increased activity of PGR protein] which results in increased expression of CITED2 mRNA; [Progesterone results in increased activity of PGR protein] which results in increased expression of CYP26A1 mRNA; [Progesterone results in increased activity of PGR protein] which results in increased expression of GATA2 mRNA; [Progesterone results in increased activity of PGR protein] which results in increased expression of KLK5 mRNA; [Progesterone results in increased activity of PGR protein] which results in increased expression of KLK6 mRNA; [Progesterone results in increased activity of PGR protein] which results in increased expression of RBP1 mRNA; bisphenol A inhibits the reaction [Progesterone results in increased expression of PGR mRNA]; Mifepristone inhibits the reaction [Progesterone results in increased expression of PGR mRNA]; Mifepristone inhibits the reaction [Progesterone results in increased expression of PGR protein]; octylphenol inhibits the reaction [Progesterone results in increased expression of PGR mRNA]; PGR gene mutant form inhibits the reaction [Progesterone results in increased expression of CCNG1 mRNA]; PGR protein affects the reaction [Progesterone results in decreased expression of BMP2 mRNA]; PGR protein affects the reaction [Progesterone results in decreased expression of BMP5 mRNA]; PGR protein affects the reaction [Progesterone results in decreased expression of WIF1 mRNA] Progesterone affects the localization of PGR protein Progesterone results in decreased expression of PGR mRNA; Progesterone results in decreased expression of PGR protein alternative form Progesterone binds to PGR protein; Progesterone binds to PGR protein alternative form [Estradiol co-treated with Progesterone] results in increased expression of PGR mRNA; [Estrogens co-treated with Progesterone] results in increased phosphorylation of PGR protein; [Ethinyl Estradiol co-treated with Progesterone] results in increased expression of PGR protein; [Mifepristone binds to and results in decreased activity of PGR protein] which results in decreased susceptibility to Progesterone; [Progesterone co-treated with Estradiol] affects the expression of PGR mRNA; Atrazine inhibits the reaction [Progesterone binds to PGR protein]; Diethylstilbestrol inhibits the reaction [[Estradiol co-treated with Progesterone] results in increased expression of PGR protein]; Estradiol promotes the reaction [Progesterone binds to PGR protein]; Mifepristone inhibits the reaction [Progesterone results in increased expression of PGR mRNA]; o,p'-DDT promotes the reaction [Progesterone binds to PGR protein]; RNF4 protein promotes the reaction [Progesterone results in increased activity of PGR protein]; Simazine inhibits the reaction [Progesterone binds to PGR protein]; Ursodeoxycholic Acid inhibits the reaction [[Ethinyl Estradiol co-treated with Progesterone] results in increased expression of PGR protein]
|
CTD |
PMID:1544902 PMID:4375319 PMID:7414049 PMID:8812239 PMID:9126867 PMID:9144411 PMID:9710597 PMID:10888668 PMID:11507064 PMID:14579009 PMID:14728856 PMID:15189034 PMID:15661853 PMID:15806153 PMID:15845616 PMID:15866122 PMID:16198674 PMID:16284289 PMID:16326432 PMID:17251523 PMID:17556502 PMID:18060946 PMID:18262749 PMID:18653720 PMID:19903701 PMID:20008677 PMID:20726854 PMID:21258428 PMID:21795739 PMID:21803136 PMID:22238285 PMID:22414680 PMID:23183084 PMID:23275455 PMID:23409146 PMID:24777823 PMID:25210133 PMID:27264040 PMID:29248852 PMID:31195007 PMID:31566189 PMID:31889325 PMID:33728745 PMID:37009741 More...
|
|
NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:14,354,398...14,413,271
|
|
| G
|
Pgrmc1
|
progesterone receptor membrane component 1
|
affects binding
|
EXP
|
Progesterone binds to PGRMC1 protein
|
CTD |
PMID:15934950 |
|
NCBI chr X:120,698,610...120,706,805
Ensembl chr X:120,698,610...120,706,805
|
|
| G
|
Phactr3
|
phosphatase and actin regulator 3
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of PHACTR3 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 3:165,205,247...165,423,692
Ensembl chr 3:185,582,796...185,801,822
|
|
| G
|
Phb1
|
prohibitin 1
|
multiple interactions
|
ISO
|
PHB1 protein inhibits the reaction [FSHB protein results in increased secretion of Progesterone]
|
CTD |
PMID:23254195 |
|
NCBI chr10:80,605,268...80,618,043
Ensembl chr10:81,102,028...81,116,233
|
|
| G
|
Phf7
|
PHD finger protein 7
|
affects expression
|
ISO
|
Progesterone affects the expression of PHF7 mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr16:6,439,968...6,452,671
Ensembl chr16:6,439,970...6,452,671
|
|
| G
|
Phlda1
|
pleckstrin homology-like domain, family A, member 1
|
increases expression multiple interactions
|
ISO
|
Progesterone results in increased expression of PHLDA1 mRNA [Estradiol co-treated with Progesterone] results in increased expression of PHLDA1 mRNA [Estradiol co-treated with Progesterone] results in decreased expression of PHLDA1 mRNA
|
CTD |
PMID:18556351 PMID:20660070 PMID:21795739 |
|
NCBI chr 7:48,853,690...48,855,894
Ensembl chr 7:48,853,260...48,857,542
|
|
| G
|
Phlda2
|
pleckstrin homology-like domain, family A, member 2
|
increases expression
|
ISO
|
Progesterone results in increased expression of PHLDA2 mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr 1:208,126,302...208,127,241
Ensembl chr 1:208,126,302...208,127,920
|
|
| G
|
Phox2a
|
paired-like homeobox 2a
|
increases expression
|
EXP
|
Progesterone results in increased expression of PHOX2A mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr 1:156,178,754...156,183,118
Ensembl chr 1:165,590,757...165,595,122
|
|
| G
|
Phyh
|
phytanoyl-CoA 2-hydroxylase
|
increases expression
|
EXP
|
Progesterone results in increased expression of PHYH mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr17:78,238,747...78,255,645
Ensembl chr17:78,238,747...78,255,645
|
|
| G
|
Pi15
|
peptidase inhibitor 15
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of PI15 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 5:6,178,427...6,206,548
Ensembl chr 5:6,174,963...6,247,841
|
|
| G
|
Pibf1
|
progesterone immunomodulatory binding factor 1
|
increases expression
|
ISO
|
Progesterone results in increased expression of PIBF1 mRNA; Progesterone results in increased expression of PIBF1 protein
|
CTD |
PMID:17701593 |
|
NCBI chr15:82,258,243...82,427,546
Ensembl chr15:82,258,468...82,427,548
|
|
| G
|
Pid1
|
phosphotyrosine interaction domain containing 1
|
multiple interactions increases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of PID1 mRNA; [Progesterone co-treated with Estradiol] results in increased expression of PID1 mRNA Progesterone results in increased expression of PID1 mRNA
|
CTD |
PMID:17404688 PMID:20660070 |
|
NCBI chr 9:92,732,471...92,951,168
Ensembl chr 9:92,734,214...92,750,070
|
|
| G
|
Piezo2
|
piezo-type mechanosensitive ion channel component 2
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of PIEZO2 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr18:58,738,734...59,115,252
Ensembl chr18:58,738,740...59,115,215
|
|
| G
|
Pik3r3
|
phosphoinositide-3-kinase regulatory subunit 3
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of PIK3R3 mRNA
|
CTD |
PMID:21795739 |
|
NCBI chr 5:134,936,790...135,009,303
Ensembl chr 5:134,934,857...135,007,762
|
|
| G
|
Pim1
|
Pim-1 proto-oncogene, serine/threonine kinase
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of PIM1 mRNA; Mifepristone promotes the reaction [Progesterone affects the expression of PIM1 mRNA]
|
CTD |
PMID:20660070 PMID:22414680 |
|
NCBI chr20:7,554,921...7,559,174
Ensembl chr20:7,556,113...7,561,764
|
|
| G
|
Pim3
|
Pim-3 proto-oncogene, serine/threonine kinase
|
increases expression
|
EXP
|
Progesterone results in increased expression of PIM3 mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr 7:119,953,377...119,956,587
Ensembl chr 7:121,832,742...121,836,259
|
|
| G
|
Pip5k1b
|
phosphatidylinositol-4-phosphate 5-kinase type 1 beta
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of PIP5K1B mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 1:231,331,836...231,610,092
Ensembl chr 1:231,340,606...231,496,812
|
|
| G
|
Pitpnb
|
phosphatidylinositol transfer protein, beta
|
affects expression
|
ISO
|
Progesterone affects the expression of PITPNB mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr12:45,249,308...45,298,388
Ensembl chr12:50,909,143...50,958,140
|
|
| G
|
Pkd1
|
polycystin 1, transient receptor potential channel interacting
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of PKD1 mRNA
|
CTD |
PMID:19693291 |
|
NCBI chr10:14,077,733...14,125,682
Ensembl chr10:14,078,679...14,125,681
|
|
| G
|
Pkhd1l1
|
PKHD1 like 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of PKHD1L1 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 7:77,505,063...77,679,994
Ensembl chr 7:77,505,152...77,679,994
|
|
| G
|
Pkia
|
cAMP-dependent protein kinase inhibitor alpha
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of PKIA mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr 2:94,398,869...94,473,638
Ensembl chr 2:96,306,184...96,321,262
|
|
| G
|
Pkm
|
pyruvate kinase M1/2
|
affects expression
|
ISO
|
Progesterone affects the expression of PKM mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr 8:68,949,731...68,975,394
Ensembl chr 8:68,948,815...68,975,396
|
|
| G
|
Pla2g10
|
phospholipase A2, group X
|
affects expression
|
ISO
|
Progesterone affects the expression of PLA2G10 mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr10:2,104,927...2,117,998
Ensembl chr10:2,104,927...2,116,172
|
|
| G
|
Pla2g4a
|
phospholipase A2 group 4A
|
increases expression
|
ISO
|
Progesterone results in increased expression of PLA2G4A mRNA
|
CTD |
PMID:18070364 |
|
NCBI chr13:64,427,921...64,572,352
Ensembl chr13:64,427,916...64,589,641
|
|
| G
|
Pla2g5
|
phospholipase A2, group V
|
increases expression decreases expression
|
EXP ISO
|
Progesterone results in increased expression of PLA2G5 mRNA Progesterone results in decreased expression of PLA2G5 mRNA
|
CTD |
PMID:20726854 PMID:22238285 |
|
NCBI chr 5:156,324,628...156,393,065
Ensembl chr 5:156,324,629...156,381,926
|
|
| G
|
Pla2g7
|
phospholipase A2 group VII
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of PLA2G7 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 9:24,859,491...24,901,747
Ensembl chr 9:24,859,502...24,901,747
|
|
| G
|
Plaat3
|
phospholipase A and acyltransferase 3
|
increases expression
|
EXP
|
Progesterone results in increased expression of PLAAT3 mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr 1:204,782,608...204,816,397
Ensembl chr 1:214,211,791...214,246,763
|
|
| G
|
Plac8
|
placenta associated 8
|
increases expression
|
ISO
|
Progesterone results in increased expression of PLAC8 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr14:9,356,950...9,378,586
Ensembl chr14:9,356,972...9,378,572
|
|
| G
|
Plat
|
plasminogen activator, tissue type
|
increases expression decreases expression
|
ISO
|
Progesterone results in increased expression of PLAT mRNA Progesterone results in decreased expression of PLAT mRNA
|
CTD |
PMID:21795739 PMID:22238285 |
|
NCBI chr16:75,943,061...76,022,037
Ensembl chr16:75,943,064...75,967,696
|
|
| G
|
Plau
|
plasminogen activator, urokinase
|
multiple interactions decreases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of PLAU mRNA; [Progesterone co-treated with Estradiol] results in decreased expression of PLAU mRNA Progesterone results in decreased expression of PLAU mRNA
|
CTD |
PMID:17404688 PMID:18070364 PMID:20660070 |
|
NCBI chr15:3,505,485...3,511,987
Ensembl chr15:3,505,487...3,512,030
|
|
| G
|
Plaur
|
plasminogen activator, urokinase receptor
|
increases expression multiple interactions
|
EXP ISO
|
Progesterone results in increased expression of PLAUR mRNA; Progesterone results in increased expression of PLAUR protein [Estradiol co-treated with Progesterone] results in decreased expression of PLAUR mRNA
|
CTD |
PMID:17170212 PMID:20660070 |
|
NCBI chr 1:89,181,363...89,196,308
Ensembl chr 1:89,178,453...89,198,130
|
|
| G
|
Plcb1
|
phospholipase C beta 1
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of PLCB1 mRNA
|
CTD |
PMID:20864642 |
|
NCBI chr 3:142,512,765...143,224,042
Ensembl chr 3:142,513,033...143,225,646
|
|
| G
|
Plcb4
|
phospholipase C, beta 4
|
increases expression
|
ISO
|
Progesterone results in increased expression of PLCB4 mRNA
|
CTD |
PMID:22238285 |
|
NCBI chr 3:143,405,721...143,775,129
Ensembl chr 3:143,405,950...143,775,113
|
|
| G
|
Plce1
|
phospholipase C, epsilon 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of PLCE1 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 1:245,655,855...245,964,966
Ensembl chr 1:245,657,080...245,963,828
|
|
| G
|
Plch1
|
phospholipase C, eta 1
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of PLCH1 mRNA
|
CTD |
PMID:21795739 |
|
NCBI chr 2:150,298,547...150,514,120
Ensembl chr 2:150,299,075...150,464,019
|
|
| G
|
Pld1
|
phospholipase D1
|
multiple interactions decreases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of PLD1 mRNA Progesterone results in decreased expression of PLD1 mRNA
|
CTD |
PMID:19693291 |
|
NCBI chr 2:112,777,820...112,975,857
Ensembl chr 2:112,777,951...112,976,245
|
|
| G
|
Plec
|
plectin
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of PLEC mRNA
|
CTD |
PMID:18037150 PMID:18070364 |
|
NCBI chr 7:109,768,447...109,829,798
Ensembl chr 7:109,768,447...109,828,089
|
|
| G
|
Plek2
|
pleckstrin 2
|
multiple interactions decreases expression
|
ISO
|
[Progesterone co-treated with Estradiol] results in decreased expression of PLEK2 mRNA Progesterone results in decreased expression of PLEK2 mRNA
|
CTD |
PMID:17404688 |
|
NCBI chr 6:103,434,156...103,452,457
Ensembl chr 6:103,434,156...103,452,371
|
|
| G
|
Plekha7
|
pleckstrin homology domain containing A7
|
increases expression
|
ISO
|
Progesterone results in increased expression of PLEKHA7 mRNA
|
CTD |
PMID:21795739 |
|
NCBI chr 1:170,364,524...170,547,843
Ensembl chr 1:179,799,040...179,982,281
|
|
| G
|
Plekho1
|
pleckstrin homology domain containing O1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of PLEKHO1 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 2:186,233,435...186,242,114
Ensembl chr 2:186,233,452...186,241,354
|
|
| G
|
Plk2
|
polo-like kinase 2
|
multiple interactions decreases expression
|
ISO EXP
|
[Estradiol co-treated with Progesterone] results in decreased expression of PLK2 mRNA Progesterone results in decreased expression of PLK2 mRNA
|
CTD |
PMID:20660070 PMID:20726854 |
|
NCBI chr 2:43,702,536...43,708,305
Ensembl chr 2:43,701,865...43,708,296
|
|
| G
|
Plk4
|
polo-like kinase 4
|
affects expression
|
ISO
|
Progesterone affects the expression of PLK4 mRNA
|
CTD |
PMID:17251523 |
|
NCBI chr 2:125,730,480...125,748,894
Ensembl chr 2:125,730,460...125,748,892
|
|
| G
|
Pllp
|
plasmolipin
|
multiple interactions increases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of PLLP mRNA Progesterone results in increased expression of PLLP mRNA
|
CTD |
PMID:20660070 PMID:22238285 |
|
NCBI chr19:10,321,080...10,341,869
Ensembl chr19:10,321,080...10,342,226
|
|
| G
|
Pln
|
phospholamban
|
increases expression multiple interactions
|
EXP
|
Progesterone results in increased expression of PLN mRNA Mifepristone inhibits the reaction [Progesterone inhibits the reaction [bisphenol A results in increased phosphorylation of PLN protein]]; Pertussis Toxin inhibits the reaction [Progesterone inhibits the reaction [bisphenol A results in increased phosphorylation of PLN protein]]; Progesterone inhibits the reaction [bisphenol A results in increased phosphorylation of PLN protein]; wortmannin inhibits the reaction [Progesterone inhibits the reaction [bisphenol A results in increased phosphorylation of PLN protein]]
|
CTD |
PMID:16376865 PMID:28324061 |
|
NCBI chr20:33,166,512...33,182,241
Ensembl chr20:33,172,494...33,182,241
|
|
| G
|
Plod2
|
procollagen lysine, 2-oxoglutarate 5-dioxygenase 2
|
increases expression
|
EXP
|
Progesterone results in increased expression of PLOD2 mRNA
|
CTD |
PMID:21770760 |
|
NCBI chr 8:101,964,318...102,047,022
Ensembl chr 8:101,964,318...102,047,022
|
|
| G
|
Plp1
|
proteolipid protein 1
|
multiple interactions
|
ISO
|
[Progesterone co-treated with Estradiol] inhibits the reaction [Cuprizone results in decreased expression of PLP1 mRNA]
|
CTD |
PMID:19031445 |
|
NCBI chr X:104,933,921...104,993,317
Ensembl chr X:104,975,780...104,993,314
|
|
| G
|
Plpp3
|
phospholipid phosphatase 3
|
increases expression
|
ISO
|
Progesterone results in increased expression of PLPP3 mRNA
|
CTD |
PMID:20864642 |
|
NCBI chr 5:125,156,000...125,231,119
Ensembl chr 5:125,155,945...125,235,667
|
|
| G
|
Plscr4
|
phospholipid scramblase 4
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of PLSCR4 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 8:92,987,290...93,026,056
Ensembl chr 8:101,866,888...101,905,831
|
|
| G
|
Plxdc1
|
plexin domain containing 1
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of PLXDC1 mRNA
|
CTD |
PMID:21795739 |
|
NCBI chr10:83,418,837...83,478,451
Ensembl chr10:83,418,837...83,478,755
|
|
| G
|
Plxnc1
|
plexin C1
|
increases expression
|
ISO
|
Progesterone results in increased expression of PLXNC1 mRNA
|
CTD |
PMID:20864642 |
|
NCBI chr 7:29,390,038...29,543,985
Ensembl chr 7:31,276,978...31,431,092
|
|
| G
|
Pmaip1
|
phorbol-12-myristate-13-acetate-induced protein 1
|
multiple interactions decreases expression
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of PMAIP1 mRNA Progesterone results in decreased expression of PMAIP1 mRNA
|
CTD |
PMID:20660070 PMID:22238285 |
|
NCBI chr18:62,255,970...62,262,384
Ensembl chr18:62,255,598...62,262,382
|
|
| G
|
Pmepa1
|
prostate transmembrane protein, androgen induced 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of PMEPA1 mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 3:182,430,193...182,478,649
Ensembl chr 3:182,430,193...182,478,649
|
|
| G
|
Pmp22
|
peripheral myelin protein 22
|
multiple interactions increases expression
|
EXP
|
Progesterone inhibits the reaction [Streptozocin results in decreased expression of PMP22 mRNA] Progesterone results in increased expression of PMP22 mRNA
|
CTD |
PMID:16787508 PMID:17187935 |
|
NCBI chr10:48,294,932...48,324,941
Ensembl chr10:48,297,437...48,324,940
|
|
| G
|
Pnliprp1
|
pancreatic lipase-related protein 1
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in increased expression of PNLIPRP1 mRNA
|
CTD |
PMID:19693291 |
|
NCBI chr 1:267,854,027...267,869,654
Ensembl chr 1:267,854,027...267,869,654
|
|
| G
|
Pnma8a
|
PNMA family member 8A
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of PNMA8A mRNA
|
CTD |
PMID:20660070 |
|
NCBI chr 1:77,629,272...77,643,156
Ensembl chr 1:86,756,168...86,815,182
|
|
| G
|
Pnoc
|
prepronociceptin
|
multiple interactions
|
EXP
|
nociceptin (1-13) amide inhibits the reaction [PNOC protein inhibits the reaction [[Estradiol co-treated with Progesterone] results in increased expression of LHB protein]]; PNOC protein inhibits the reaction [[Estradiol co-treated with Progesterone] results in increased expression of LHB protein]
|
CTD |
PMID:17640482 |
|
NCBI chr15:43,800,240...43,827,841
Ensembl chr15:43,800,246...43,827,470
|
|
| G
|
Pnrc2
|
proline-rich nuclear receptor coactivator 2
|
multiple interactions
|
ISO
|
[Estradiol co-treated with Progesterone] results in decreased expression of PNRC2 mRNA
|
CTD |
PMID:21453500 |
|
NCBI chr 5:148,103,966...148,106,950
Ensembl chr 5:153,378,863...153,390,748
|
|
| G
|
Podxl
|
podocalyxin-like
|
increases expression
|
EXP
|
Progesterone results in increased expression of PODXL mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr 4:61,102,434...61,149,131
Ensembl chr 4:61,102,419...61,149,789
|
|
| G
|
Pof1b
|
POF1B, actin binding protein
|
multiple interactions decreases expression
|
ISO
|
NCOA2 protein affects the reaction [Progesterone results in decreased expression of POF1B mRNA]
|
CTD |
PMID:17556502 |
|
NCBI chr X:81,875,348...81,942,046
Ensembl chr X:81,875,348...81,941,906
|
|
| G
|
Pofut1
|
protein O-fucosyltransferase 1
|
decreases expression
|
ISO
|
Progesterone results in decreased expression of POFUT1 mRNA
|
CTD |
PMID:18037150 |
|
NCBI chr 3:162,168,855...162,195,798
Ensembl chr 3:162,168,606...162,195,018
|
|
| G
|
Pold1
|
DNA polymerase delta 1, catalytic subunit
|
decreases expression
|
EXP
|
Progesterone results in decreased expression of POLD1 mRNA
|
CTD |
PMID:20726854 |
|
NCBI chr 1:95,025,462...95,041,559
Ensembl chr 1:104,162,016...104,172,982
|
|
| G
|
Pole4
|
DNA pol |